Danio rerio

0 known processes

ldhd

lactate dehydrogenase D

(Aliases: zgc:55447,wu:fi36b04)

ldhd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.136
nitrogen compound metabolic process GO:0006807 319 0.130
organonitrogen compound metabolic process GO:1901564 74 0.102
nucleobase containing compound metabolic process GO:0006139 274 0.099
rna modification GO:0009451 2 0.080
response to stress GO:0006950 263 0.077
heterocycle metabolic process GO:0046483 290 0.076
cellular aromatic compound metabolic process GO:0006725 295 0.070
positive regulation of cellular catabolic process GO:0031331 3 0.065
cellular biosynthetic process GO:0044249 286 0.061
single organism metabolic process GO:0044710 217 0.061
gtp metabolic process GO:0046039 4 0.054
nuclear transport GO:0051169 4 0.053
rna metabolic process GO:0016070 219 0.051
regulation of metabolic process GO:0019222 359 0.051
establishment of protein localization to organelle GO:0072594 4 0.050
response to chemical GO:0042221 320 0.049
negative regulation of protein phosphorylation GO:0001933 4 0.046
organic cyclic compound metabolic process GO:1901360 301 0.046
guanosine containing compound metabolic process GO:1901068 4 0.045
regulation of gene expression GO:0010468 265 0.045
aging GO:0007568 2 0.044
regulation of cellular biosynthetic process GO:0031326 245 0.043
small molecule metabolic process GO:0044281 77 0.043
guanosine containing compound catabolic process GO:1901069 2 0.042
positive regulation of catabolic process GO:0009896 4 0.042
rna localization GO:0006403 4 0.041
organic substance biosynthetic process GO:1901576 289 0.041
ribonucleoside monophosphate catabolic process GO:0009158 4 0.040
regulation of cell communication GO:0010646 232 0.040
nucleobase containing small molecule metabolic process GO:0055086 32 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
purine nucleoside monophosphate catabolic process GO:0009128 4 0.038
purine nucleotide metabolic process GO:0006163 27 0.038
regulation of purine nucleotide catabolic process GO:0033121 2 0.037
autophagy GO:0006914 4 0.036
macroautophagy GO:0016236 1 0.036
positive regulation of transport GO:0051050 2 0.036
multicellular organism growth GO:0035264 4 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
nucleic acid metabolic process GO:0090304 244 0.034
larval development GO:0002164 2 0.034
biosynthetic process GO:0009058 294 0.034
g1 s transition of mitotic cell cycle GO:0000082 1 0.033
regulation of primary metabolic process GO:0080090 311 0.033
phagocytosis GO:0006909 3 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
gene expression GO:0010467 252 0.032
positive regulation of gtpase activity GO:0043547 1 0.031
carbohydrate derivative metabolic process GO:1901135 61 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
regulation of cytokine production GO:0001817 3 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.031
regulation of protein localization to nucleus GO:1900180 2 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
response to uv GO:0009411 3 0.031
cellular response to nutrient levels GO:0031669 2 0.030
cellular response to extracellular stimulus GO:0031668 2 0.030
atp catabolic process GO:0006200 4 0.030
regulation of organ growth GO:0046620 3 0.030
protein localization to nucleus GO:0034504 3 0.030
regulation of gtp catabolic process GO:0033124 2 0.030
homeostasis of number of cells GO:0048872 62 0.030
maintenance of location GO:0051235 4 0.030
cellular response to starvation GO:0009267 1 0.029
regulation of biosynthetic process GO:0009889 250 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
negative regulation of protein localization to nucleus GO:1900181 2 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.029
regulation of protein transport GO:0051223 3 0.029
nucleoside monophosphate catabolic process GO:0009125 4 0.029
negative regulation of protein kinase activity GO:0006469 4 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
response to organic substance GO:0010033 153 0.028
cellular response to external stimulus GO:0071496 2 0.028
positive regulation of jun kinase activity GO:0043507 2 0.028
developmental programmed cell death GO:0010623 4 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
gtp catabolic process GO:0006184 2 0.027
regulation of response to stimulus GO:0048583 269 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.026
meiotic nuclear division GO:0007126 4 0.026
regulation of meiotic cell cycle GO:0051445 1 0.026
negative chemotaxis GO:0050919 1 0.026
mitochondrion organization GO:0007005 4 0.026
response to drug GO:0042493 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
positive regulation of cell adhesion GO:0045785 1 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
membrane fusion GO:0061025 2 0.025
response to external stimulus GO:0009605 264 0.025
negative regulation of kinase activity GO:0033673 4 0.024
cell cycle g1 s phase transition GO:0044843 1 0.024
single organism membrane fusion GO:0044801 2 0.024
neuron differentiation GO:0030182 353 0.024
signal transduction GO:0007165 455 0.024
negative regulation of protein transport GO:0051224 3 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
positive regulation of nucleoside metabolic process GO:0045979 1 0.023
mitotic dna damage checkpoint GO:0044773 4 0.023
microtubule organizing center organization GO:0031023 1 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
regulation of biological quality GO:0065008 263 0.023
ribose phosphate metabolic process GO:0019693 27 0.023
regulation of rho protein signal transduction GO:0035023 2 0.023
rna export from nucleus GO:0006405 1 0.023
regulation of intracellular protein transport GO:0033157 3 0.022
cellular carbohydrate metabolic process GO:0044262 4 0.022
response to monosaccharide GO:0034284 3 0.022
embryonic organ development GO:0048568 381 0.022
cellular response to organic substance GO:0071310 105 0.022
regulation of autophagy GO:0010506 3 0.022
chordate embryonic development GO:0043009 271 0.022
rna transport GO:0050658 2 0.022
hormone transport GO:0009914 2 0.022
positive regulation of translation GO:0045727 1 0.021
purine containing compound metabolic process GO:0072521 29 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of reproductive process GO:2000241 4 0.021
stem cell maintenance GO:0019827 4 0.021
cellular component biogenesis GO:0044085 178 0.021
transport GO:0006810 220 0.021
positive regulation of nucleotide catabolic process GO:0030813 1 0.021
cellular response to radiation GO:0071478 4 0.021
protein import GO:0017038 3 0.021
response to nutrient GO:0007584 3 0.021
response to hexose GO:0009746 3 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
homeostatic process GO:0042592 142 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
meiotic cell cycle process GO:1903046 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
meiosis i GO:0007127 1 0.020
establishment of localization in cell GO:0051649 77 0.019
intracellular signal transduction GO:0035556 85 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
regulation of gtpase activity GO:0043087 2 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
single organism nuclear import GO:1902593 3 0.019
response to glucose GO:0009749 3 0.019
regulation of synapse organization GO:0050807 3 0.019
nucleic acid transport GO:0050657 2 0.019
cell proliferation GO:0008283 80 0.019
cellular localization GO:0051641 97 0.019
negative regulation of biological process GO:0048519 304 0.019
establishment of localization GO:0051234 244 0.019
positive regulation of secretion GO:0051047 1 0.018
cellular component disassembly GO:0022411 1 0.018
rho protein signal transduction GO:0007266 5 0.018
cellular respiration GO:0045333 3 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
cytokinesis GO:0000910 3 0.018
ras protein signal transduction GO:0007265 7 0.018
cell projection organization GO:0030030 284 0.017
thioester metabolic process GO:0035383 1 0.017
positive regulation of cellular process GO:0048522 201 0.017
negative regulation of metabolic process GO:0009892 86 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
establishment of rna localization GO:0051236 3 0.017
adult behavior GO:0030534 2 0.017
activation of mapk activity GO:0000187 3 0.017
regulation of blood pressure GO:0008217 1 0.017
protein targeting to nucleus GO:0044744 3 0.017
lipid oxidation GO:0034440 1 0.017
germ line stem cell maintenance GO:0030718 2 0.017
regulation of rna metabolic process GO:0051252 224 0.017
digestive system development GO:0055123 289 0.017
tube closure GO:0060606 1 0.017
regulation of dendrite development GO:0050773 3 0.016
double strand break repair GO:0006302 3 0.016
regulation of localization GO:0032879 104 0.016
adherens junction organization GO:0034332 4 0.016
cellular amide metabolic process GO:0043603 4 0.016
stem cell division GO:0017145 1 0.016
brain development GO:0007420 293 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
regulation of signaling GO:0023051 235 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
sister chromatid cohesion GO:0007062 2 0.016
tissue remodeling GO:0048771 4 0.016
protein modification by small protein removal GO:0070646 1 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
regulation of developmental process GO:0050793 247 0.016
carbohydrate homeostasis GO:0033500 1 0.016
amine metabolic process GO:0009308 2 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
response to glucocorticoid GO:0051384 1 0.016
cilium morphogenesis GO:0060271 85 0.015
lipid storage GO:0019915 1 0.015
digestive tract development GO:0048565 265 0.015
nucleobase containing compound transport GO:0015931 2 0.015
positive regulation of biological process GO:0048518 253 0.015
system process GO:0003008 185 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
organelle organization GO:0006996 227 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
regulation of dna replication GO:0006275 3 0.015
peptide metabolic process GO:0006518 1 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.015
nuclear import GO:0051170 3 0.015
cellular component morphogenesis GO:0032989 336 0.015
cellular amine metabolic process GO:0044106 2 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
nucleotide metabolic process GO:0009117 28 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
response to corticosteroid GO:0031960 1 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
centrosome duplication GO:0051298 1 0.014
regulation of cell cycle GO:0051726 52 0.014
xenobiotic metabolic process GO:0006805 4 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
primary neural tube formation GO:0014020 1 0.014
membrane lipid biosynthetic process GO:0046467 2 0.014
nuclear export GO:0051168 1 0.014
cellular response to stress GO:0033554 62 0.014
phosphorus metabolic process GO:0006793 109 0.014
regulation of apoptotic process GO:0042981 98 0.014
aromatic compound catabolic process GO:0019439 15 0.014
regulation of ras gtpase activity GO:0032318 2 0.014
b cell activation GO:0042113 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
protein secretion GO:0009306 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
regulation of multicellular organismal process GO:0051239 277 0.013
single organism organelle organization GO:1902589 199 0.013
cellular response to light stimulus GO:0071482 4 0.013
retina development in camera type eye GO:0060041 146 0.013
cellular component assembly GO:0022607 170 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
nucleobase containing compound catabolic process GO:0034655 15 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
phagocytosis engulfment GO:0006911 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
death GO:0016265 121 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
eye morphogenesis GO:0048592 144 0.013
negative regulation of cytokine production GO:0001818 1 0.013
centrosome organization GO:0051297 1 0.013
positive regulation of cell cycle GO:0045787 3 0.013
oxidative phosphorylation GO:0006119 1 0.013
cellular catabolic process GO:0044248 27 0.013
cellular nitrogen compound catabolic process GO:0044270 15 0.013
neurological system process GO:0050877 62 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
negative regulation of secretion GO:0051048 2 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
response to vitamin GO:0033273 3 0.013
apoptotic process involved in development GO:1902742 2 0.013
cell migration GO:0016477 237 0.012
regulation of cell shape GO:0008360 1 0.012
central nervous system development GO:0007417 387 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
protein complex disassembly GO:0043241 1 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
response to wounding GO:0009611 116 0.012
generation of neurons GO:0048699 385 0.012
regulation of protein complex assembly GO:0043254 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
macromolecular complex disassembly GO:0032984 1 0.012
organic acid metabolic process GO:0006082 31 0.012
recombinational repair GO:0000725 1 0.012
response to carbohydrate GO:0009743 3 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
cognition GO:0050890 1 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of cellular component organization GO:0051128 86 0.012
eye development GO:0001654 277 0.012
heart development GO:0007507 313 0.012
transcription dna templated GO:0006351 181 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
telomere organization GO:0032200 1 0.012
phosphorylation GO:0016310 69 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
meiotic chromosome segregation GO:0045132 3 0.011
cartilage development GO:0051216 96 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
protein stabilization GO:0050821 2 0.011
organic cyclic compound catabolic process GO:1901361 15 0.011
single organism biosynthetic process GO:0044711 71 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
negative regulation of defense response GO:0031348 2 0.011
gland development GO:0048732 143 0.011
peptidyl serine modification GO:0018209 2 0.011
mrna 3 end processing GO:0031124 2 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of protein targeting GO:1903533 2 0.011
response to ketone GO:1901654 1 0.011
glycosyl compound metabolic process GO:1901657 11 0.011
head development GO:0060322 303 0.011
fatty acid oxidation GO:0019395 1 0.011
tube morphogenesis GO:0035239 349 0.011
muscle structure development GO:0061061 196 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of inflammatory response GO:0050727 2 0.011
negative regulation of cellular process GO:0048523 283 0.011
mononuclear cell proliferation GO:0032943 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of dna recombination GO:0000018 2 0.011
negative regulation of translation GO:0017148 1 0.011
multi organism process GO:0051704 134 0.011
single organism localization GO:1902578 225 0.011
female sex differentiation GO:0046660 4 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
cell part morphogenesis GO:0032990 246 0.010
embryonic skeletal joint development GO:0072498 3 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
erythrocyte homeostasis GO:0034101 55 0.010
apoptotic process GO:0006915 116 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
regulation of protein catabolic process GO:0042176 1 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
organic substance catabolic process GO:1901575 28 0.010
myeloid cell homeostasis GO:0002262 56 0.010
oxoacid metabolic process GO:0043436 31 0.010

ldhd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.019
inherited metabolic disorder DOID:655 0 0.018