Danio rerio

58 known processes

leo1

Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

(Aliases: zgc:77374,MGC77374)

leo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 271 0.840
larval development GO:0002164 2 0.759
Worm
nitrogen compound metabolic process GO:0006807 319 0.610
chordate embryonic development GO:0043009 271 0.478
regulation of multicellular organismal development GO:2000026 223 0.465
regulation of metabolic process GO:0019222 359 0.401
rna metabolic process GO:0016070 219 0.321
transport GO:0006810 220 0.314
Worm
regulation of cellular metabolic process GO:0031323 320 0.307
regulation of primary metabolic process GO:0080090 311 0.273
regulation of multicellular organismal process GO:0051239 277 0.273
Worm
immune system process GO:0002376 241 0.268
heart development GO:0007507 313 0.254
signal transduction GO:0007165 455 0.248
cellular macromolecule metabolic process GO:0044260 391 0.245
locomotion GO:0040011 313 0.244
Worm
establishment of localization GO:0051234 244 0.225
Worm
central nervous system development GO:0007417 387 0.218
alternative mrna splicing via spliceosome GO:0000380 1 0.216
negative regulation of cellular process GO:0048523 283 0.206
nucleobase containing compound metabolic process GO:0006139 274 0.205
meiotic nuclear division GO:0007126 4 0.201
multicellular organism growth GO:0035264 4 0.196
Worm
cell surface receptor signaling pathway GO:0007166 325 0.187
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.175
heterocycle metabolic process GO:0046483 290 0.174
synaptic growth at neuromuscular junction GO:0051124 2 0.171
cellular nitrogen compound metabolic process GO:0034641 290 0.167
regulation of macromolecule metabolic process GO:0060255 317 0.160
regulation of developmental process GO:0050793 247 0.159
Worm
organic cyclic compound metabolic process GO:1901360 301 0.153
lipid storage GO:0019915 1 0.143
organelle organization GO:0006996 227 0.142
negative regulation of metabolic process GO:0009892 86 0.139
hematopoietic or lymphoid organ development GO:0048534 191 0.127
cellular component movement GO:0006928 335 0.127
gene expression GO:0010467 252 0.127
blood vessel morphogenesis GO:0048514 216 0.125
aging GO:0007568 2 0.124
regulation of meiotic cell cycle GO:0051445 1 0.124
macromolecule biosynthetic process GO:0009059 227 0.121
regulation of rna metabolic process GO:0051252 224 0.120
regulation of signal transduction GO:0009966 225 0.117
mitotic cell cycle GO:0000278 64 0.116
maintenance of location GO:0051235 4 0.112
establishment of protein localization to organelle GO:0072594 4 0.112
regulation of nitrogen compound metabolic process GO:0051171 251 0.112
organic cyclic compound biosynthetic process GO:1901362 223 0.111
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.107
growth GO:0040007 174 0.107
Worm
regulation of signaling GO:0023051 235 0.104
modification dependent macromolecule catabolic process GO:0043632 3 0.104
stem cell proliferation GO:0072089 4 0.104
intracellular signal transduction GO:0035556 85 0.100
negative regulation of cellular metabolic process GO:0031324 77 0.098
positive regulation of biological process GO:0048518 253 0.097
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.096
neuron development GO:0048666 262 0.095
regulation of multicellular organism growth GO:0040014 4 0.094
Worm
organic substance biosynthetic process GO:1901576 289 0.094
cellular aromatic compound metabolic process GO:0006725 295 0.094
regulation of cellular biosynthetic process GO:0031326 245 0.093
vasculature development GO:0001944 278 0.092
regulation of synapse organization GO:0050807 3 0.092
hemopoiesis GO:0030097 183 0.091
aromatic compound biosynthetic process GO:0019438 217 0.091
positive regulation of metabolic process GO:0009893 108 0.088
regulation of biological quality GO:0065008 263 0.086
positive regulation of catabolic process GO:0009896 4 0.084
cell migration GO:0016477 237 0.082
negative regulation of biological process GO:0048519 304 0.081
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.080
heterocycle biosynthetic process GO:0018130 215 0.079
rna biosynthetic process GO:0032774 181 0.079
positive regulation of cellular process GO:0048522 201 0.078
digestive tract morphogenesis GO:0048546 231 0.076
positive regulation of cellular metabolic process GO:0031325 94 0.076
regulation of mrna processing GO:0050684 3 0.076
immune system development GO:0002520 191 0.075
sensory organ development GO:0007423 393 0.074
biosynthetic process GO:0009058 294 0.073
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.072
stem cell division GO:0017145 1 0.071
digestive system development GO:0055123 289 0.070
cellular protein catabolic process GO:0044257 4 0.069
response to drug GO:0042493 3 0.068
pigmentation GO:0043473 85 0.067
response to chemical GO:0042221 320 0.067
developmental growth GO:0048589 166 0.067
Worm
regulation of response to stimulus GO:0048583 269 0.066
reproduction GO:0000003 40 0.066
Worm
small gtpase mediated signal transduction GO:0007264 8 0.066
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.065
regulation of cell cycle GO:0051726 52 0.064
single organism metabolic process GO:0044710 217 0.064
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.064
regulation of rna biosynthetic process GO:2001141 213 0.064
blood vessel development GO:0001568 246 0.064
single organism reproductive process GO:0044702 40 0.063
Worm
transcription dna templated GO:0006351 181 0.062
regulation of mrna splicing via spliceosome GO:0048024 3 0.061
digestive tract development GO:0048565 265 0.059
positive regulation of signaling GO:0023056 56 0.058
protein metabolic process GO:0019538 183 0.058
regulation of protein ubiquitination GO:0031396 3 0.058
localization of cell GO:0051674 244 0.058
negative regulation of gene expression GO:0010629 65 0.058
regulation of biosynthetic process GO:0009889 250 0.055
positive regulation of biosynthetic process GO:0009891 68 0.055
positive regulation of response to stimulus GO:0048584 80 0.054
locomotory behavior GO:0007626 34 0.054
cell motility GO:0048870 244 0.054
nucleic acid metabolic process GO:0090304 244 0.054
transcription from rna polymerase ii promoter GO:0006366 80 0.054
positive regulation of nucleic acid templated transcription GO:1903508 57 0.053
positive regulation of signal transduction GO:0009967 56 0.053
positive regulation of cell cycle GO:0045787 3 0.052
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.052
tube morphogenesis GO:0035239 349 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
regulation of epithelial cell proliferation GO:0050678 3 0.050
cellular protein modification process GO:0006464 100 0.049
cellular biosynthetic process GO:0044249 286 0.049
meiotic chromosome segregation GO:0045132 3 0.049
neural crest cell development GO:0014032 62 0.049
nucleobase containing compound biosynthetic process GO:0034654 205 0.048
brain development GO:0007420 293 0.048
positive regulation of cellular biosynthetic process GO:0031328 68 0.048
single organism organelle organization GO:1902589 199 0.047
wnt signaling pathway GO:0016055 80 0.046
er to golgi vesicle mediated transport GO:0006888 1 0.045
positive regulation of developmental process GO:0051094 50 0.045
Worm
positive regulation of macromolecule metabolic process GO:0010604 93 0.045
single organism transport GO:0044765 206 0.043
organic acid metabolic process GO:0006082 31 0.042
positive regulation of cellular catabolic process GO:0031331 3 0.041
positive regulation of synapse assembly GO:0051965 1 0.041
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.040
regulation of synapse assembly GO:0051963 3 0.040
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.040
gastrulation GO:0007369 208 0.040
heart morphogenesis GO:0003007 156 0.040
developmental process involved in reproduction GO:0003006 27 0.038
Worm
cellular amine metabolic process GO:0044106 2 0.038
nucleic acid templated transcription GO:0097659 181 0.038
ras protein signal transduction GO:0007265 7 0.037
positive regulation of cell communication GO:0010647 56 0.037
cell proliferation GO:0008283 80 0.037
generation of neurons GO:0048699 385 0.037
cytokinesis GO:0000910 3 0.037
system process GO:0003008 185 0.036
regulation of gene expression GO:0010468 265 0.036
positive regulation of multicellular organismal process GO:0051240 52 0.036
Worm
protein import GO:0017038 3 0.036
macromolecule localization GO:0033036 54 0.035
neuroblast proliferation GO:0007405 2 0.035
myeloid cell differentiation GO:0030099 86 0.035
protein localization to nucleus GO:0034504 3 0.035
organonitrogen compound metabolic process GO:1901564 74 0.034
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.034
response to wounding GO:0009611 116 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
positive regulation of ras protein signal transduction GO:0046579 1 0.033
stem cell differentiation GO:0048863 117 0.033
morphogenesis of an epithelium GO:0002009 333 0.033
regulation of stem cell proliferation GO:0072091 2 0.033
skeletal system morphogenesis GO:0048705 102 0.033
positive regulation of gene expression GO:0010628 71 0.033
positive regulation of transcription dna templated GO:0045893 57 0.033
positive regulation of rna biosynthetic process GO:1902680 57 0.033
regulation of neural precursor cell proliferation GO:2000177 3 0.032
central nervous system neuron development GO:0021954 29 0.032
negative regulation of neural precursor cell proliferation GO:2000178 1 0.032
mesenchymal cell differentiation GO:0048762 87 0.032
positive regulation of cell death GO:0010942 29 0.032
single organism nuclear import GO:1902593 3 0.032
embryonic skeletal system development GO:0048706 97 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
negative regulation of synapse assembly GO:0051964 2 0.030
nuclear import GO:0051170 3 0.030
oligodendrocyte differentiation GO:0048709 23 0.030
positive regulation of transport GO:0051050 2 0.030
rna splicing GO:0008380 16 0.030
protein import into nucleus GO:0006606 3 0.029
regulation of transcription dna templated GO:0006355 213 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.029
embryonic skeletal system morphogenesis GO:0048704 93 0.029
tissue remodeling GO:0048771 4 0.029
compound eye development GO:0048749 2 0.028
amine metabolic process GO:0009308 2 0.028
nuclear transport GO:0051169 4 0.028
regulation of cell proliferation GO:0042127 37 0.028
regulation of epidermis development GO:0045682 2 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
regulation of cell division GO:0051302 12 0.027
regulation of rac protein signal transduction GO:0035020 1 0.027
regulation of protein catabolic process GO:0042176 1 0.027
regulation of cellular component organization GO:0051128 86 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
synapse assembly GO:0007416 9 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.026
regulation of apoptotic process GO:0042981 98 0.026
transmission of nerve impulse GO:0019226 19 0.026
response to organic substance GO:0010033 153 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
regulation of erk1 and erk2 cascade GO:0070372 4 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
endocytosis GO:0006897 16 0.026
Worm
multi organism process GO:0051704 134 0.026
positive regulation of chromosome organization GO:2001252 1 0.026
mitotic cell cycle process GO:1903047 48 0.025
head development GO:0060322 303 0.025
positive regulation of rna metabolic process GO:0051254 59 0.025
mitotic nuclear division GO:0007067 18 0.025
apoptotic process GO:0006915 116 0.025
embryonic heart tube development GO:0035050 133 0.025
chemosensory behavior GO:0007635 1 0.025
regulation of tube size GO:0035150 2 0.025
regulation of nervous system development GO:0051960 90 0.024
regulation of binding GO:0051098 3 0.024
hepaticobiliary system development GO:0061008 98 0.024
oocyte anterior posterior axis specification GO:0007314 4 0.024
regulation of circadian rhythm GO:0042752 4 0.024
cell cycle GO:0007049 93 0.024
organelle fission GO:0048285 23 0.024
regulation of cellular response to oxidative stress GO:1900407 2 0.024
regulation of rho protein signal transduction GO:0035023 2 0.023
eye development GO:0001654 277 0.023
striated muscle tissue development GO:0014706 110 0.023
single fertilization GO:0007338 3 0.023
cellular component morphogenesis GO:0032989 336 0.023
regulation of oocyte development GO:0060281 3 0.023
angiogenesis GO:0001525 158 0.023
nuclear division GO:0000280 23 0.023
single organism localization GO:1902578 225 0.023
intracellular mrna localization GO:0008298 1 0.023
regulation of developmental growth GO:0048638 38 0.023
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
response to external stimulus GO:0009605 264 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
camera type eye development GO:0043010 222 0.022
regulation of localization GO:0032879 104 0.022
mesenchyme development GO:0060485 127 0.022
skeletal muscle organ development GO:0060538 78 0.022
death GO:0016265 121 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
mrna splicing via spliceosome GO:0000398 10 0.021
macromolecule modification GO:0043412 111 0.021
negative regulation of molecular function GO:0044092 23 0.021
pole plasm assembly GO:0007315 4 0.021
exocrine pancreas development GO:0031017 28 0.020
positive regulation of myeloid cell differentiation GO:0045639 2 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
cell division GO:0051301 20 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
embryonic hemopoiesis GO:0035162 53 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
stem cell maintenance GO:0019827 4 0.020
regulation of cell activation GO:0050865 1 0.020
regulation of endothelial cell proliferation GO:0001936 1 0.020
liver development GO:0001889 96 0.020
negative regulation of kinase activity GO:0033673 4 0.019
cellular component biogenesis GO:0044085 178 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
mesenchymal cell development GO:0014031 78 0.019
regulation of chromosome segregation GO:0051983 1 0.019
fertilization GO:0009566 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
vesicle localization GO:0051648 27 0.019
muscle tissue development GO:0060537 110 0.019
regulation of reproductive process GO:2000241 4 0.019
actomyosin structure organization GO:0031032 53 0.019
regulation of cell differentiation GO:0045595 142 0.019
cellular component assembly GO:0022607 170 0.019
actin filament based process GO:0030029 64 0.018
regulation of intracellular signal transduction GO:1902531 57 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regeneration GO:0031099 91 0.018
regulation of neurogenesis GO:0050767 87 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
cellular response to external stimulus GO:0071496 2 0.018
adult behavior GO:0030534 2 0.018
cellular ketone metabolic process GO:0042180 11 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
transmembrane transport GO:0055085 120 0.017
regulation of protein transport GO:0051223 3 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
protein modification process GO:0036211 100 0.017
neural crest cell differentiation GO:0014033 72 0.017
regulation of response to oxidative stress GO:1902882 2 0.017
positive regulation of cell division GO:0051781 2 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
reproductive process GO:0022414 40 0.017
Worm
cell cycle g2 m phase transition GO:0044839 4 0.017
response to stress GO:0006950 263 0.017
skeletal muscle tissue development GO:0007519 67 0.017
multicellular organismal signaling GO:0035637 22 0.017
neuron differentiation GO:0030182 353 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.016
reproductive structure development GO:0048608 5 0.016
Worm
regulation of embryonic development GO:0045995 47 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
behavior GO:0007610 74 0.016
meiotic cell cycle process GO:1903046 3 0.016
cellular localization GO:0051641 97 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
regulation of oxidative stress induced cell death GO:1903201 2 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
forebrain development GO:0030900 96 0.016
regulation of protein targeting GO:1903533 2 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
neuron projection regeneration GO:0031102 16 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cell death in response to oxidative stress GO:0036473 2 0.015
regulation of cell death GO:0010941 103 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
oxoacid metabolic process GO:0043436 31 0.015
gliogenesis GO:0042063 45 0.015
rna processing GO:0006396 25 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
programmed cell death GO:0012501 119 0.015
neurotransmitter transport GO:0006836 2 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
regionalization GO:0003002 274 0.015
gland development GO:0048732 143 0.015
regulation of protein metabolic process GO:0051246 56 0.015
germ cell development GO:0007281 22 0.015
epithelial cell differentiation GO:0030855 116 0.015
mechanosensory behavior GO:0007638 2 0.014
negative regulation of rna splicing GO:0033119 1 0.014
aorta development GO:0035904 4 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
protein acylation GO:0043543 3 0.014
regulation of autophagy GO:0010506 3 0.014
regulation of cell communication GO:0010646 232 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
axon development GO:0061564 166 0.014
viral process GO:0016032 1 0.014
phosphorus metabolic process GO:0006793 109 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
negative regulation of cell death GO:0060548 60 0.014
primary neural tube formation GO:0014020 1 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
mrna processing GO:0006397 14 0.013
regulation of bone remodeling GO:0046850 2 0.013
cellular response to starvation GO:0009267 1 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
mitotic metaphase plate congression GO:0007080 1 0.013
positive regulation of programmed cell death GO:0043068 29 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
gtp metabolic process GO:0046039 4 0.013
negative regulation of signal transduction GO:0009968 94 0.013
notch signaling pathway GO:0007219 35 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
regulation of notch signaling pathway GO:0008593 16 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
negative regulation of transcription dna templated GO:0045892 45 0.013
multi organism reproductive process GO:0044703 36 0.013
muscle structure development GO:0061061 196 0.013
anterior posterior pattern specification GO:0009952 152 0.013
tissue regeneration GO:0042246 74 0.013
positive regulation of protein metabolic process GO:0051247 23 0.013
regulation of rna splicing GO:0043484 8 0.013
histone deacetylation GO:0016575 2 0.013
wound healing GO:0042060 90 0.013
negative regulation of defense response GO:0031348 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
golgi vesicle transport GO:0048193 3 0.012
neuron projection development GO:0031175 180 0.012
sympathetic nervous system development GO:0048485 3 0.012
ear development GO:0043583 127 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.012
phagocytosis GO:0006909 3 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
cytoplasm organization GO:0007028 4 0.012
peripheral nervous system development GO:0007422 55 0.012
axonogenesis GO:0007409 152 0.012
regulation of protein binding GO:0043393 3 0.012
organic substance transport GO:0071702 58 0.012
cytoskeleton organization GO:0007010 96 0.012
modification of morphology or physiology of other organism GO:0035821 4 0.012
signal transduction by phosphorylation GO:0023014 18 0.012
negative regulation of leukocyte differentiation GO:1902106 1 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
cell death GO:0008219 121 0.012
neurological system process GO:0050877 62 0.011
positive regulation of multi organism process GO:0043902 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
autophagy GO:0006914 4 0.011
proteolysis GO:0006508 38 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
stem cell development GO:0048864 82 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
chromosome organization GO:0051276 31 0.011
skeletal system development GO:0001501 181 0.011
regulation of growth GO:0040008 42 0.011
Worm
negative regulation of cell communication GO:0010648 96 0.011
muscle organ development GO:0007517 101 0.011
sexual reproduction GO:0019953 36 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
response to uv GO:0009411 3 0.011
regulation of cell cycle process GO:0010564 20 0.011
regulation of mitotic cell cycle embryonic GO:0009794 2 0.011
positive regulation of neuron death GO:1901216 1 0.011
regulation of cytokine production GO:0001817 3 0.011
mrna metabolic process GO:0016071 20 0.011
regulation of cell shape GO:0008360 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
negative regulation of signaling GO:0023057 96 0.011
pancreas development GO:0031016 84 0.011
regulation of programmed cell death GO:0043067 101 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
chemotaxis GO:0006935 104 0.010
actin cytoskeleton organization GO:0030036 63 0.010
posttranscriptional gene silencing by rna GO:0035194 3 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
neurotransmitter secretion GO:0007269 2 0.010
response to abiotic stimulus GO:0009628 122 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
positive regulation of cell differentiation GO:0045597 30 0.010
catabolic process GO:0009056 32 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
embryonic organ development GO:0048568 381 0.010
cell projection morphogenesis GO:0048858 244 0.010

leo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.027
motor neuron disease DOID:231 0 0.027
neurodegenerative disease DOID:1289 0 0.027
amyotrophic lateral sclerosis DOID:332 0 0.027
central nervous system disease DOID:331 0 0.027
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011