Danio rerio

38 known processes

lft1

lefty1

(Aliases: antivin,atv,xx:tdsubc_2b12,cb73,ik:tdsubc_2b12)

lft1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid metabolic process GO:0090304 244 0.998
Mouse
digestive tract morphogenesis GO:0048546 231 0.994
Mouse
nucleic acid templated transcription GO:0097659 181 0.990
Mouse
diencephalon development GO:0021536 58 0.990
regulation of nodal signaling pathway GO:1900107 4 0.988
Mouse
tube morphogenesis GO:0035239 349 0.980
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.977
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.974
Mouse
regionalization GO:0003002 274 0.972
digestive system development GO:0055123 289 0.968
Mouse
regulation of signaling GO:0023051 235 0.966
Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.965
regulation of cellular metabolic process GO:0031323 320 0.965
Mouse
regulation of transcription dna templated GO:0006355 213 0.962
Mouse
gene expression GO:0010467 252 0.960
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.949
Mouse
regulation of biosynthetic process GO:0009889 250 0.944
Mouse
regulation of multicellular organismal development GO:2000026 223 0.944
regulation of nucleic acid templated transcription GO:1903506 213 0.939
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.938
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.930
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.928
Mouse
regulation of primary metabolic process GO:0080090 311 0.922
Mouse
notochord development GO:0030903 54 0.921
regulation of developmental process GO:0050793 247 0.919
heart jogging GO:0003146 40 0.919
transcription dna templated GO:0006351 181 0.917
Mouse
heart field specification GO:0003128 1 0.917
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.916
Mouse
organic substance biosynthetic process GO:1901576 289 0.914
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.913
Mouse
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.910
regulation of rna metabolic process GO:0051252 224 0.898
Mouse
specification of symmetry GO:0009799 204 0.896
regulation of cell communication GO:0010646 232 0.895
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.895
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.892
Mouse
macromolecule biosynthetic process GO:0009059 227 0.890
Mouse
determination of left right asymmetry in diencephalon GO:0035462 4 0.889
morphogenesis of an epithelium GO:0002009 333 0.881
hindbrain development GO:0030902 91 0.877
negative regulation of cellular process GO:0048523 283 0.874
Mouse
head development GO:0060322 303 0.867
gastrulation GO:0007369 208 0.867
Mouse
notochord morphogenesis GO:0048570 17 0.863
regulation of gene expression GO:0010468 265 0.860
Mouse
determination of left right asymmetry in nervous system GO:0035545 4 0.857
transcription from rna polymerase ii promoter GO:0006366 80 0.848
Mouse
signal transduction GO:0007165 455 0.844
Mouse
rna biosynthetic process GO:0032774 181 0.843
Mouse
response to chemical GO:0042221 320 0.842
Mouse
bmp signaling pathway GO:0030509 52 0.841
heterocycle biosynthetic process GO:0018130 215 0.834
Mouse
cell morphogenesis GO:0000902 289 0.828
cellular macromolecule biosynthetic process GO:0034645 224 0.824
Mouse
regulation of signal transduction GO:0009966 225 0.822
Mouse
embryonic organ development GO:0048568 381 0.820
cell surface receptor signaling pathway GO:0007166 325 0.819
Mouse
regulation of heart morphogenesis GO:2000826 17 0.814
regulation of metabolic process GO:0019222 359 0.807
Mouse
ear morphogenesis GO:0042471 64 0.799
eye development GO:0001654 277 0.789
organic cyclic compound metabolic process GO:1901360 301 0.784
Mouse
determination of heart left right asymmetry GO:0061371 117 0.784
negative regulation of protein complex assembly GO:0031333 1 0.780
Mouse
generation of neurons GO:0048699 385 0.776
segmentation GO:0035282 97 0.774
positive regulation of rna metabolic process GO:0051254 59 0.771
positive regulation of biosynthetic process GO:0009891 68 0.763
heterocycle metabolic process GO:0046483 290 0.761
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.743
Mouse
cellular component movement GO:0006928 335 0.742
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.739
Mouse
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.733
mesoderm development GO:0007498 88 0.731
heart development GO:0007507 313 0.722
positive regulation of biological process GO:0048518 253 0.720
cell migration involved in gastrulation GO:0042074 79 0.701
Mouse
determination of left right symmetry GO:0007368 179 0.693
bmp signaling pathway involved in heart development GO:0061312 15 0.689
digestive tract development GO:0048565 265 0.687
Mouse
floor plate formation GO:0021508 12 0.686
regulation of macromolecule metabolic process GO:0060255 317 0.685
Mouse
muscle cell differentiation GO:0042692 139 0.681
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.678
Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.666
heart formation GO:0060914 13 0.665
Zebrafish
cell fate specification GO:0001708 68 0.664
anterior posterior pattern specification GO:0009952 152 0.664
Mouse
convergent extension involved in gastrulation GO:0060027 71 0.660
cell migration GO:0016477 237 0.658
Mouse
heart morphogenesis GO:0003007 156 0.658
Zebrafish Mouse
blood vessel development GO:0001568 246 0.657
brain development GO:0007420 293 0.656
cellular aromatic compound metabolic process GO:0006725 295 0.654
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.647
Mouse
cellular biosynthetic process GO:0044249 286 0.639
Mouse
embryonic hemopoiesis GO:0035162 53 0.626
cell projection organization GO:0030030 284 0.626
specification of organ position GO:0010159 3 0.620
determination of bilateral symmetry GO:0009855 204 0.602
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.600
Mouse
cardiocyte differentiation GO:0035051 44 0.591
blood vessel morphogenesis GO:0048514 216 0.586
optic placode formation GO:0001743 4 0.575
biosynthetic process GO:0009058 294 0.572
Mouse
negative regulation of biological process GO:0048519 304 0.566
Mouse
positive regulation of gene expression GO:0010628 71 0.564
positive regulation of cellular process GO:0048522 201 0.557
neuron differentiation GO:0030182 353 0.555
convergent extension GO:0060026 118 0.544
dorsal ventral pattern formation GO:0009953 125 0.544
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.542
negative regulation of nodal signaling pathway GO:1900108 4 0.529
Mouse
vasculature development GO:0001944 278 0.527
formation of primary germ layer GO:0001704 62 0.525
notochord formation GO:0014028 6 0.522
rna metabolic process GO:0016070 219 0.508
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.508
cellular nitrogen compound metabolic process GO:0034641 290 0.507
Mouse
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.503
cell differentiation in spinal cord GO:0021515 40 0.501
neural plate pattern specification GO:0060896 12 0.501
central nervous system neuron differentiation GO:0021953 74 0.496
neuron development GO:0048666 262 0.495
negative regulation of mesodermal cell fate specification GO:0042662 3 0.492
negative regulation of activin receptor signaling pathway GO:0032926 5 0.475
Mouse
cardioblast migration GO:0003260 7 0.473
liver development GO:0001889 96 0.470
negative regulation of cell communication GO:0010648 96 0.460
Mouse
taxis GO:0042330 109 0.457
endoderm formation GO:0001706 29 0.450
central nervous system development GO:0007417 387 0.445
negative regulation of response to stimulus GO:0048585 104 0.441
Mouse
optic placode formation involved in camera type eye formation GO:0046619 3 0.432
locomotion GO:0040011 313 0.432
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.428
endodermal cell fate specification GO:0001714 17 0.424
muscle structure development GO:0061061 196 0.421
inner ear development GO:0048839 126 0.413
regulation of cardiac muscle tissue development GO:0055024 1 0.406
embryonic heart tube development GO:0035050 133 0.406
sensory organ development GO:0007423 393 0.406
wnt signaling pathway GO:0016055 80 0.402
establishment of protein localization to organelle GO:0072594 4 0.402
gall bladder development GO:0061010 1 0.401
ameboidal type cell migration GO:0001667 143 0.398
Mouse
growth GO:0040007 174 0.395
regulation of anatomical structure morphogenesis GO:0022603 130 0.395
positive regulation of rna biosynthetic process GO:1902680 57 0.393
neuron projection development GO:0031175 180 0.393
hematopoietic or lymphoid organ development GO:0048534 191 0.392
larval development GO:0002164 2 0.380
spemann organizer formation GO:0060061 10 0.358
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.358
camera type eye morphogenesis GO:0048593 108 0.357
gastrulation with mouth forming second GO:0001702 44 0.355
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.352
axial mesodermal cell fate specification GO:0048327 3 0.350
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.347
negative regulation of cellular biosynthetic process GO:0031327 55 0.347
Mouse
regulation of embryonic development GO:0045995 47 0.339
eye morphogenesis GO:0048592 144 0.335
t cell differentiation in thymus GO:0033077 6 0.334
cellular component morphogenesis GO:0032989 336 0.333
neural plate regionalization GO:0060897 10 0.332
bmp signaling pathway involved in heart jogging GO:0003303 14 0.331
regulation of mesoderm development GO:2000380 11 0.329
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.329
cardiac cell fate commitment GO:0060911 1 0.328
positive regulation of cellular metabolic process GO:0031325 94 0.327
multi organism process GO:0051704 134 0.326
chordate embryonic development GO:0043009 271 0.326
positive regulation of metabolic process GO:0009893 108 0.311
axial mesoderm formation GO:0048320 4 0.310
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.306
heart looping GO:0001947 94 0.305
sensory organ morphogenesis GO:0090596 200 0.295
morphogenesis of an epithelial sheet GO:0002011 49 0.294
vasculogenesis GO:0001570 41 0.292
epithelial tube morphogenesis GO:0060562 148 0.285
mesoderm formation GO:0001707 43 0.281
regulation of establishment of protein localization GO:0070201 4 0.275
striated muscle tissue development GO:0014706 110 0.274
female gonad development GO:0008585 4 0.269
anterior posterior axis specification embryo GO:0008595 5 0.262
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.259
photoreceptor cell differentiation GO:0046530 55 0.250
negative regulation of gene expression GO:0010629 65 0.249
Mouse
regulation of response to stimulus GO:0048583 269 0.248
Mouse
muscle tissue development GO:0060537 110 0.246
cell motility GO:0048870 244 0.241
Mouse
mesenchyme development GO:0060485 127 0.239
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.239
regulation of organ morphogenesis GO:2000027 35 0.236
cellular macromolecule metabolic process GO:0044260 391 0.233
Mouse
axial mesoderm structural organization GO:0048331 2 0.232
anterior posterior axis specification GO:0009948 20 0.231
Mouse
hepatic duct development GO:0061011 2 0.230
death GO:0016265 121 0.226
retina morphogenesis in camera type eye GO:0060042 79 0.225
cell fate commitment GO:0045165 99 0.223
hematopoietic progenitor cell differentiation GO:0002244 23 0.222
regulation of cell differentiation GO:0045595 142 0.220
camera type eye photoreceptor cell differentiation GO:0060219 19 0.219
atrial ventricular junction remodeling GO:0003294 2 0.215
lateral mesoderm development GO:0048368 23 0.210
heart valve formation GO:0003188 4 0.209
regulation of endodermal cell fate specification GO:0042663 15 0.209
mesoderm morphogenesis GO:0048332 51 0.208
specification of organ identity GO:0010092 2 0.208
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.208
striated muscle cell differentiation GO:0051146 129 0.207
cardiac chamber development GO:0003205 19 0.207
negative regulation of signal transduction GO:0009968 94 0.206
Mouse
gliogenesis GO:0042063 45 0.204
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.203
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.203
protein import GO:0017038 3 0.198
positive regulation of macromolecule metabolic process GO:0010604 93 0.198
positive regulation of muscle tissue development GO:1901863 1 0.196
blastoderm segmentation GO:0007350 6 0.196
angiogenesis GO:0001525 158 0.194
regulation of bmp signaling pathway GO:0030510 39 0.192
positive regulation of signaling GO:0023056 56 0.192
embryonic heart tube left right pattern formation GO:0060971 5 0.190
photoreceptor cell fate commitment GO:0046552 1 0.188
endodermal digestive tract morphogenesis GO:0061031 2 0.187
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.186
female sex differentiation GO:0046660 4 0.185
regulation of gastrulation GO:0010470 24 0.181
axis specification GO:0009798 43 0.180
Mouse
mesenchymal cell development GO:0014031 78 0.179
aging GO:0007568 2 0.178
endoderm development GO:0007492 49 0.178
pons development GO:0021548 11 0.176
determination of dorsal identity GO:0048263 13 0.175
gland development GO:0048732 143 0.173
embryonic eye morphogenesis GO:0048048 30 0.170
regulation of wnt signaling pathway GO:0030111 53 0.166
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.166
outflow tract morphogenesis GO:0003151 1 0.165
retina development in camera type eye GO:0060041 146 0.161
pancreas development GO:0031016 84 0.158
mononuclear cell proliferation GO:0032943 1 0.155
positive regulation of jun kinase activity GO:0043507 2 0.153
regulation of multicellular organismal process GO:0051239 277 0.153
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.151
organ formation GO:0048645 17 0.151
Zebrafish
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.150
negative regulation of gastrulation GO:2000542 11 0.149
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.149
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.144
embryonic axis specification GO:0000578 12 0.143
heart growth GO:0060419 7 0.142
negative regulation of transcription dna templated GO:0045892 45 0.141
Mouse
cellular response to chemical stimulus GO:0070887 157 0.138
development of primary female sexual characteristics GO:0046545 4 0.137
camera type eye development GO:0043010 222 0.136
pectoral fin morphogenesis GO:0035138 29 0.136
nodal signaling pathway GO:0038092 7 0.134
Mouse
programmed cell death GO:0012501 119 0.133
heart contraction GO:0060047 71 0.131
neuron fate specification GO:0048665 20 0.126
nephron epithelium morphogenesis GO:0072088 1 0.126
stem cell differentiation GO:0048863 117 0.125
embryonic organ morphogenesis GO:0048562 274 0.125
cardiac atrium development GO:0003230 4 0.125
negative regulation of leukocyte differentiation GO:1902106 1 0.121
regulation of cell death GO:0010941 103 0.120
atrioventricular valve formation GO:0003190 3 0.119
cellular protein metabolic process GO:0044267 129 0.117
retinal ganglion cell axon guidance GO:0031290 35 0.115
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.114
sexual reproduction GO:0019953 36 0.113
pectoral fin development GO:0033339 50 0.113
hemopoiesis GO:0030097 183 0.112
glial cell differentiation GO:0010001 42 0.112
negative regulation of cell differentiation GO:0045596 46 0.110
regulation of binding GO:0051098 3 0.109
axon development GO:0061564 166 0.109
appendage morphogenesis GO:0035107 56 0.109
immune system process GO:0002376 241 0.108
neural tube development GO:0021915 62 0.106
floor plate morphogenesis GO:0033505 12 0.102
single organism nuclear import GO:1902593 3 0.102
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.101
response to external stimulus GO:0009605 264 0.101
pharyngeal muscle development GO:0043282 4 0.101
positive regulation of nucleic acid templated transcription GO:1903508 57 0.100
oligodendrocyte differentiation GO:0048709 23 0.100
somite development GO:0061053 96 0.098
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.097
inner ear morphogenesis GO:0042472 63 0.097
negative regulation of multicellular organismal process GO:0051241 69 0.096
establishment of localization GO:0051234 244 0.096
negative regulation of signaling GO:0023057 96 0.093
Mouse
ectoderm formation GO:0001705 2 0.093
ear development GO:0043583 127 0.092
cardiac chamber formation GO:0003207 4 0.092
determination of pancreatic left right asymmetry GO:0035469 11 0.091
negative regulation of macromolecule metabolic process GO:0010605 76 0.091
Mouse
endodermal cell differentiation GO:0035987 19 0.090
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.090
Mouse
atrioventricular valve morphogenesis GO:0003181 6 0.088
embryonic heart tube morphogenesis GO:0003143 108 0.088
pharynx development GO:0060465 5 0.088
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.088
regulation of protein targeting GO:1903533 2 0.087
hypothalamus development GO:0021854 14 0.087
embryonic foregut morphogenesis GO:0048617 1 0.087
negative regulation of rna metabolic process GO:0051253 48 0.087
Mouse
embryonic pattern specification GO:0009880 44 0.087
regulation of cellular response to growth factor stimulus GO:0090287 35 0.086
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.086
regulation of cellular component movement GO:0051270 55 0.085
cell maturation GO:0048469 23 0.085
cardiac atrium morphogenesis GO:0003209 2 0.084
forebrain regionalization GO:0021871 4 0.084
positive regulation of response to stimulus GO:0048584 80 0.083
single organism reproductive process GO:0044702 40 0.083
positive regulation of transport GO:0051050 2 0.082
atrioventricular valve development GO:0003171 11 0.082
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.082
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.082
neuron projection morphogenesis GO:0048812 161 0.081
lymphocyte proliferation GO:0046651 1 0.081
regulation of nucleocytoplasmic transport GO:0046822 2 0.080
epiboly GO:0090504 41 0.080
regulation of cardiac muscle cell differentiation GO:2000725 1 0.080
eye photoreceptor cell development GO:0042462 30 0.080
regeneration GO:0031099 91 0.080
leukocyte proliferation GO:0070661 1 0.079
pericardium morphogenesis GO:0003344 1 0.079
t cell activation GO:0042110 6 0.079
endodermal cell fate commitment GO:0001711 18 0.078
anterior head development GO:0097065 2 0.078
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.077
heart process GO:0003015 71 0.077
positive regulation of signal transduction GO:0009967 56 0.077
renal system development GO:0072001 94 0.076
somitogenesis GO:0001756 87 0.076
cartilage development GO:0051216 96 0.076
kidney development GO:0001822 92 0.075
stem cell maintenance GO:0019827 4 0.075
response to stress GO:0006950 263 0.074
cell death GO:0008219 121 0.074
protein targeting to nucleus GO:0044744 3 0.074
immune system development GO:0002520 191 0.073
positive regulation of muscle organ development GO:0048636 1 0.073
hepatocyte differentiation GO:0070365 1 0.071
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.071
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.070
Mouse
developmental growth GO:0048589 166 0.069
cell part morphogenesis GO:0032990 246 0.069
protein import into nucleus GO:0006606 3 0.069
somatic stem cell maintenance GO:0035019 1 0.068
response to other organism GO:0051707 97 0.068
regulation of cartilage development GO:0061035 7 0.068
mesodermal cell differentiation GO:0048333 21 0.068
negative regulation of metabolic process GO:0009892 86 0.067
Mouse
wnt signaling pathway involved in heart development GO:0003306 5 0.067
localization of cell GO:0051674 244 0.066
Mouse
radial glial cell differentiation GO:0060019 2 0.066
appendage development GO:0048736 80 0.066
cardiac muscle cell differentiation GO:0055007 30 0.066
regulation of cell proliferation GO:0042127 37 0.065
Mouse
limb bud formation GO:0060174 2 0.065
pharyngeal system development GO:0060037 18 0.065
regulation of canonical wnt signaling pathway GO:0060828 34 0.065
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.064
Mouse
neural tube patterning GO:0021532 33 0.064
intermediate mesoderm development GO:0048389 2 0.064
hepaticobiliary system development GO:0061008 98 0.064
regulation of protein import into nucleus GO:0042306 2 0.064
urogenital system development GO:0001655 97 0.064
oligodendrocyte cell fate specification GO:0021778 4 0.063
positive regulation of catabolic process GO:0009896 4 0.063
embryonic pectoral fin morphogenesis GO:0035118 24 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.063
Mouse
negative regulation of wnt signaling pathway GO:0030178 30 0.063
stem cell development GO:0048864 82 0.063
ectodermal placode formation GO:0060788 26 0.063
embryonic camera type eye formation GO:0060900 10 0.062
response to organic substance GO:0010033 153 0.062
Mouse
lipid storage GO:0019915 1 0.062
positive regulation of map kinase activity GO:0043406 3 0.061
tripartite regional subdivision GO:0007351 5 0.061
muscle cell development GO:0055001 115 0.061
axonogenesis GO:0007409 152 0.061
regulation of cell fate specification GO:0042659 20 0.061
blood circulation GO:0008015 87 0.061
cell morphogenesis involved in differentiation GO:0000904 195 0.060
cardiac conduction system development GO:0003161 1 0.060
nephron morphogenesis GO:0072028 2 0.060
cardiac chamber morphogenesis GO:0003206 12 0.059
chemotaxis GO:0006935 104 0.059
muscle organ development GO:0007517 101 0.059
cellular protein modification process GO:0006464 100 0.058
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.057
behavior GO:0007610 74 0.057
mesendoderm development GO:0048382 10 0.057
system process GO:0003008 185 0.057
metencephalon development GO:0022037 27 0.057
photoreceptor cell development GO:0042461 40 0.057
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.056
Mouse
regulation of neurogenesis GO:0050767 87 0.055
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.055
eye photoreceptor cell differentiation GO:0001754 45 0.055
protein localization to nucleus GO:0034504 3 0.055
thrombocyte differentiation GO:0002574 4 0.054
notochord cell differentiation GO:0060034 18 0.054
cardiac muscle cell development GO:0055013 20 0.054
regulation of protein transport GO:0051223 3 0.054
nuclear import GO:0051170 3 0.054
regulation of endodermal cell differentiation GO:1903224 15 0.054
neural crest cell migration GO:0001755 42 0.053
cell projection morphogenesis GO:0048858 244 0.053
forebrain development GO:0030900 96 0.052
protein metabolic process GO:0019538 183 0.052
mesodermal cell fate specification GO:0007501 12 0.051
erk1 and erk2 cascade GO:0070371 4 0.051
left right pattern formation GO:0060972 19 0.051
neurological system process GO:0050877 62 0.050
negative regulation of muscle tissue development GO:1901862 2 0.050
cell cell signaling GO:0007267 52 0.049
multi organism reproductive process GO:0044703 36 0.048
regulation of protein localization to nucleus GO:1900180 2 0.048
mediolateral intercalation GO:0060031 3 0.048
single organism transport GO:0044765 206 0.048
glial cell fate specification GO:0021780 4 0.048
negative regulation of embryonic development GO:0045992 11 0.048
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.048
foregut morphogenesis GO:0007440 4 0.048
ventricular cardiac muscle tissue development GO:0003229 3 0.047
regulation of apoptotic process GO:0042981 98 0.047
connective tissue development GO:0061448 99 0.047
positive regulation of cell communication GO:0010647 56 0.047
heart valve development GO:0003170 14 0.046
convergent extension involved in organogenesis GO:0060029 10 0.046
regulation of protein complex assembly GO:0043254 3 0.046
Mouse
regulation of transcription involved in cell fate commitment GO:0060850 1 0.046
developmental process involved in reproduction GO:0003006 27 0.045
oocyte maturation GO:0001556 4 0.045
regulation of skeletal muscle tissue development GO:0048641 4 0.045
maintenance of location GO:0051235 4 0.045
regulation of cell growth GO:0001558 29 0.045
semicircular canal development GO:0060872 24 0.045
fourth ventricle development GO:0021592 8 0.044
negative regulation of bmp signaling pathway GO:0030514 13 0.044
neural retina development GO:0003407 49 0.044
phosphate containing compound metabolic process GO:0006796 108 0.044
non canonical wnt signaling pathway GO:0035567 13 0.044
positive regulation of epithelial cell differentiation GO:0030858 2 0.044
developmental growth involved in morphogenesis GO:0060560 86 0.044
protein complex assembly GO:0006461 30 0.044
Mouse
regulation of muscle tissue development GO:1901861 6 0.043
embryonic digestive tract morphogenesis GO:0048557 3 0.043
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.043
positive regulation of striated muscle tissue development GO:0045844 1 0.042
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.042
Mouse
regulation of growth GO:0040008 42 0.042
positive regulation of translation GO:0045727 1 0.042
cellular response to organic substance GO:0071310 105 0.042
myeloid cell differentiation GO:0030099 86 0.041
cardiac muscle fiber development GO:0048739 3 0.041
regulation of anterior head development GO:2000742 2 0.041
cellular response to external stimulus GO:0071496 2 0.041
negative regulation of apoptotic process GO:0043066 55 0.041
regulation of translational initiation GO:0006446 1 0.041
ventral spinal cord development GO:0021517 35 0.040
dorsal ventral axis specification GO:0009950 14 0.040
t cell differentiation GO:0030217 6 0.039
chemical homeostasis GO:0048878 49 0.039
regulation of response to stress GO:0080134 36 0.039
hepatocyte proliferation GO:0072574 2 0.039
leukocyte activation GO:0045321 12 0.039
embryonic skeletal joint development GO:0072498 3 0.038
muscle fiber development GO:0048747 52 0.038
regulation of reproductive process GO:2000241 4 0.037
striated muscle cell development GO:0055002 108 0.037
ectodermal placode morphogenesis GO:0071697 32 0.037
limbic system development GO:0021761 16 0.037
dna metabolic process GO:0006259 27 0.037
endocrine pancreas development GO:0031018 27 0.037
negative regulation of axon regeneration GO:0048681 4 0.037
positive regulation of developmental process GO:0051094 50 0.037
endocardial cell differentiation GO:0060956 5 0.036
semicircular canal morphogenesis GO:0048752 18 0.036
negative regulation of cell fate specification GO:0009996 11 0.036
response to retinoic acid GO:0032526 6 0.036
Mouse
regulation of organ growth GO:0046620 3 0.036
cell migration to the midline involved in heart development GO:0003318 12 0.036
regulation of cellular component organization GO:0051128 86 0.036
Mouse
canonical wnt signaling pathway GO:0060070 48 0.035
negative regulation of endodermal cell fate specification GO:0042664 8 0.035
motor neuron axon guidance GO:0008045 23 0.035

lft1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.109
musculoskeletal system disease DOID:17 0 0.076