Danio rerio

18 known processes

lgals2b

lectin, galactoside-binding, soluble, 2b

(Aliases: MGC66283,Drgal1-L3,lgals1l3,zgc:66283)

lgals2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of wound healing GO:0061041 2 0.286
Zebrafish
monovalent inorganic cation transport GO:0015672 42 0.206
regulation of metal ion transport GO:0010959 4 0.170
striated muscle cell development GO:0055002 108 0.160
Zebrafish
establishment of endothelial barrier GO:0061028 3 0.146
blood vessel morphogenesis GO:0048514 216 0.142
regulation of sodium ion transport GO:0002028 2 0.126
cellular response to xenobiotic stimulus GO:0071466 35 0.125
striated muscle tissue development GO:0014706 110 0.119
Zebrafish
positive regulation of wound healing GO:0090303 1 0.111
Zebrafish
blood vessel development GO:0001568 246 0.101
sensory organ development GO:0007423 393 0.095
response to nutrient GO:0007584 3 0.094
metal ion transport GO:0030001 58 0.088
cell motility GO:0048870 244 0.084
response to stress GO:0006950 263 0.080
Zebrafish
cellular component movement GO:0006928 335 0.080
response to wounding GO:0009611 116 0.078
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.075
maintenance of location GO:0051235 4 0.073
vasculature development GO:0001944 278 0.072
skeletal muscle fiber development GO:0048741 35 0.071
Zebrafish
skeletal muscle organ development GO:0060538 78 0.070
Zebrafish
oxoacid metabolic process GO:0043436 31 0.070
establishment of localization GO:0051234 244 0.069
myotube cell development GO:0014904 35 0.069
Zebrafish
angiogenesis GO:0001525 158 0.069
response to xenobiotic stimulus GO:0009410 45 0.065
muscle fiber development GO:0048747 52 0.064
Zebrafish
positive regulation of transport GO:0051050 2 0.062
intestinal cholesterol absorption GO:0030299 2 0.061
sodium ion transport GO:0006814 24 0.061
aging GO:0007568 2 0.059
cellular modified amino acid metabolic process GO:0006575 3 0.058
cellular amino acid metabolic process GO:0006520 7 0.057
single organism localization GO:1902578 225 0.055
response to transition metal nanoparticle GO:1990267 28 0.054
epiboly GO:0090504 41 0.054
carboxylic acid metabolic process GO:0019752 22 0.054
larval development GO:0002164 2 0.053
xenobiotic metabolic process GO:0006805 4 0.051
neuromast development GO:0048884 46 0.051
heart looping GO:0001947 94 0.051
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.051
Human
stem cell maintenance GO:0019827 4 0.050
digestive tract morphogenesis GO:0048546 231 0.049
wound healing GO:0042060 90 0.048
Zebrafish
response to chemical GO:0042221 320 0.048
muscle structure development GO:0061061 196 0.048
Zebrafish Mouse
regulation of tube size GO:0035150 2 0.047
organic acid metabolic process GO:0006082 31 0.047
lipid digestion GO:0044241 3 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.046
neural crest cell development GO:0014032 62 0.046
lipid storage GO:0019915 1 0.045
system process GO:0003008 185 0.044
muscle tissue development GO:0060537 110 0.044
Zebrafish
regulation of muscle contraction GO:0006937 3 0.044
regulation of blood vessel size GO:0050880 2 0.042
transport GO:0006810 220 0.042
multicellular organism growth GO:0035264 4 0.042
secondary metabolic process GO:0019748 3 0.042
cellular amine metabolic process GO:0044106 2 0.041
digestive system development GO:0055123 289 0.041
single organism metabolic process GO:0044710 217 0.040
regulation of multicellular organism growth GO:0040014 4 0.039
morphogenesis of an epithelial sheet GO:0002011 49 0.038
gastrulation with mouth forming second GO:0001702 44 0.037
response to vitamin GO:0033273 3 0.037
muscle cell differentiation GO:0042692 139 0.037
Zebrafish Mouse
sprouting angiogenesis GO:0002040 53 0.036
striated muscle cell differentiation GO:0051146 129 0.036
Zebrafish
regulation of biological quality GO:0065008 263 0.035
epithelial cell development GO:0002064 42 0.035
gastrulation GO:0007369 208 0.035
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.034
adherens junction organization GO:0034332 4 0.034
response to glucocorticoid GO:0051384 1 0.034
adult behavior GO:0030534 2 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.034
lateral line system development GO:0048925 76 0.033
lipid catabolic process GO:0016042 4 0.033
regulation of localization GO:0032879 104 0.033
mesenchyme development GO:0060485 127 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
determination of left right symmetry GO:0007368 179 0.033
brain development GO:0007420 293 0.032
organic cyclic compound metabolic process GO:1901360 301 0.032
generation of neurons GO:0048699 385 0.032
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.032
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
embryonic heart tube morphogenesis GO:0003143 108 0.031
muscle organ development GO:0007517 101 0.031
Zebrafish
tube morphogenesis GO:0035239 349 0.031
one carbon compound transport GO:0019755 14 0.031
cell aging GO:0007569 2 0.030
cellular component morphogenesis GO:0032989 336 0.030
muscle cell development GO:0055001 115 0.030
Zebrafish
response to vitamin b3 GO:0033552 2 0.030
small molecule metabolic process GO:0044281 77 0.030
urogenital system development GO:0001655 97 0.029
myotube differentiation GO:0014902 45 0.029
Zebrafish
purine nucleoside monophosphate catabolic process GO:0009128 4 0.029
zinc ion homeostasis GO:0055069 1 0.029
intestinal absorption GO:0050892 2 0.029
carbon dioxide transport GO:0015670 3 0.028
head development GO:0060322 303 0.028
positive regulation of epithelial cell migration GO:0010634 2 0.028
mesenchymal cell development GO:0014031 78 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
Zebrafish
central nervous system development GO:0007417 387 0.026
regulation of response to stress GO:0080134 36 0.026
Zebrafish
peptidyl serine modification GO:0018209 2 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
organelle fusion GO:0048284 3 0.026
regionalization GO:0003002 274 0.026
growth GO:0040007 174 0.025
response to external biotic stimulus GO:0043207 97 0.025
endothelial cell development GO:0001885 12 0.025
regulation of autophagy GO:0010506 3 0.025
response to cadmium ion GO:0046686 14 0.025
gas transport GO:0015669 3 0.025
i kappab kinase nf kappab signaling GO:0007249 4 0.025
Human
epithelial tube morphogenesis GO:0060562 148 0.024
sensory perception of chemical stimulus GO:0007606 3 0.024
organelle organization GO:0006996 227 0.024
heterocycle metabolic process GO:0046483 290 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
ion transmembrane transport GO:0034220 91 0.024
cell migration GO:0016477 237 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
alpha amino acid metabolic process GO:1901605 3 0.023
ameboidal type cell migration GO:0001667 143 0.023
cellular ketone metabolic process GO:0042180 11 0.023
response to external stimulus GO:0009605 264 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
amine metabolic process GO:0009308 2 0.023
zinc ion transport GO:0006829 2 0.023
positive regulation of cell cycle GO:0045787 3 0.023
atp catabolic process GO:0006200 4 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
phagocytosis GO:0006909 3 0.022
cellular biosynthetic process GO:0044249 286 0.022
regulation of response to stimulus GO:0048583 269 0.022
Human Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.021
endocardial cushion morphogenesis GO:0003203 3 0.021
regulation of ion transport GO:0043269 22 0.021
cation transport GO:0006812 81 0.020
digestive tract development GO:0048565 265 0.020
ion transport GO:0006811 114 0.020
smooth muscle contraction GO:0006939 2 0.020
membrane fusion GO:0061025 2 0.020
transmembrane transport GO:0055085 120 0.020
regulation of binding GO:0051098 3 0.020
cellular response to methanol GO:0071405 4 0.020
tissue regeneration GO:0042246 74 0.020
fat soluble vitamin metabolic process GO:0006775 4 0.019
cell substrate adhesion GO:0031589 4 0.019
negative regulation of biological process GO:0048519 304 0.019
heart development GO:0007507 313 0.019
immune system process GO:0002376 241 0.019
Mouse
blood circulation GO:0008015 87 0.019
oocyte maturation GO:0001556 4 0.019
endocardial cushion formation GO:0003272 2 0.019
response to amphetamine GO:0001975 1 0.018
regulation of cell activation GO:0050865 1 0.018
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
embryonic organ development GO:0048568 381 0.018
organic acid catabolic process GO:0016054 3 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
eye development GO:0001654 277 0.018
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.018
meiotic cell cycle process GO:1903046 3 0.018
response to amine GO:0014075 1 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
Human
epithelial cell differentiation GO:0030855 116 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
localization of cell GO:0051674 244 0.017
skeletal muscle tissue development GO:0007519 67 0.017
Zebrafish
regulation of neurogenesis GO:0050767 87 0.017
Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
glial cell migration GO:0008347 3 0.017
somitogenesis GO:0001756 87 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
response to organic cyclic compound GO:0014070 51 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
single organism membrane fusion GO:0044801 2 0.016
circulatory system process GO:0003013 87 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
plasma membrane repair GO:0001778 2 0.016
aromatic compound biosynthetic process GO:0019438 217 0.015
sensory system development GO:0048880 76 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
response to other organism GO:0051707 97 0.015
leukocyte differentiation GO:0002521 25 0.015
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
lipid oxidation GO:0034440 1 0.015
mesenchymal cell differentiation GO:0048762 87 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
embryonic heart tube development GO:0035050 133 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
cellular hormone metabolic process GO:0034754 19 0.015
locomotion GO:0040011 313 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
photoreceptor cell differentiation GO:0046530 55 0.015
sensory organ morphogenesis GO:0090596 200 0.015
stem cell differentiation GO:0048863 117 0.015
embryonic organ morphogenesis GO:0048562 274 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
defense response to bacterium GO:0042742 22 0.014
regulation of metabolic process GO:0019222 359 0.014
single organism organelle organization GO:1902589 199 0.014
osteoclast development GO:0036035 1 0.014
peptide transport GO:0015833 1 0.014
autophagy GO:0006914 4 0.014
response to unfolded protein GO:0006986 2 0.014
neural crest cell migration GO:0001755 42 0.014
cell matrix adhesion GO:0007160 4 0.014
sulfur compound metabolic process GO:0006790 13 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
muscle system process GO:0003012 20 0.014
anterior posterior pattern specification GO:0009952 152 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
segmentation GO:0035282 97 0.014
regulation of blood pressure GO:0008217 1 0.014
regulation of transcription dna templated GO:0006355 213 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
peptide metabolic process GO:0006518 1 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
response to drug GO:0042493 3 0.013
somite development GO:0061053 96 0.013
neural crest cell differentiation GO:0014033 72 0.013
blood coagulation GO:0007596 12 0.013
oligopeptide transport GO:0006857 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
response to abiotic stimulus GO:0009628 122 0.013
lateral line development GO:0048882 66 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
regulation of mrna processing GO:0050684 3 0.013
response to inorganic substance GO:0010035 38 0.013
dsrna fragmentation GO:0031050 1 0.013
protein homooligomerization GO:0051260 3 0.012
chordate embryonic development GO:0043009 271 0.012
neurological system process GO:0050877 62 0.012
monocarboxylic acid catabolic process GO:0072329 3 0.012
regulation of blood coagulation GO:0030193 1 0.012
regulation of transport GO:0051049 45 0.012
cardiac atrium development GO:0003230 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
stem cell development GO:0048864 82 0.012
pronephros development GO:0048793 69 0.012
nuclear transport GO:0051169 4 0.012
adherens junction maintenance GO:0034334 2 0.012
heart morphogenesis GO:0003007 156 0.012
spinal cord development GO:0021510 46 0.012
regulation of response to wounding GO:1903034 11 0.012
Zebrafish
developmental growth GO:0048589 166 0.012
cognition GO:0050890 1 0.012
cell substrate junction assembly GO:0007044 2 0.012
oxidation reduction process GO:0055114 41 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
cell substrate adherens junction assembly GO:0007045 1 0.012
carboxylic acid catabolic process GO:0046395 3 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
cell morphogenesis GO:0000902 289 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
regulation of intracellular ph GO:0051453 1 0.011
fat soluble vitamin biosynthetic process GO:0042362 2 0.011
intracellular signal transduction GO:0035556 85 0.011
Human
cellular macromolecule metabolic process GO:0044260 391 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
zinc ion transmembrane transport GO:0071577 1 0.011
regulation of protein catabolic process GO:0042176 1 0.011
endothelium development GO:0003158 25 0.011
regulation of coagulation GO:0050818 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
single organism transport GO:0044765 206 0.011
germ line stem cell maintenance GO:0030718 2 0.011
cellular component disassembly GO:0022411 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
translational initiation GO:0006413 3 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
negative regulation of metabolic process GO:0009892 86 0.011
nucleic acid templated transcription GO:0097659 181 0.011
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.011
biosynthetic process GO:0009058 294 0.011
regulation of organ growth GO:0046620 3 0.011
sexual reproduction GO:0019953 36 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
multi organism process GO:0051704 134 0.011
nuclear import GO:0051170 3 0.011
response to mechanical stimulus GO:0009612 24 0.011
response to biotic stimulus GO:0009607 97 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regeneration GO:0031099 91 0.010
cellular response to nutrient levels GO:0031669 2 0.010
cellular aldehyde metabolic process GO:0006081 4 0.010
peripheral nervous system development GO:0007422 55 0.010
regulation of protein transport GO:0051223 3 0.010
phagocytosis engulfment GO:0006911 1 0.010
protein oligomerization GO:0051259 7 0.010
fatty acid catabolic process GO:0009062 1 0.010
response to corticosteroid GO:0031960 1 0.010
cellular response to unfolded protein GO:0034620 2 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
renal system development GO:0072001 94 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010
rna processing GO:0006396 25 0.010

lgals2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.102
cardiovascular system disease DOID:1287 0 0.034
musculoskeletal system disease DOID:17 0 0.024
muscular disease DOID:0080000 0 0.017
myopathy DOID:423 0 0.017
muscle tissue disease DOID:66 0 0.017
heart disease DOID:114 0 0.016
cardiomyopathy DOID:0050700 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.016
immune system disease DOID:2914 0 0.015
bone marrow disease DOID:4961 0 0.015
hematopoietic system disease DOID:74 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011