Danio rerio

34 known processes

lgi1a

leucine-rich, glioma inactivated 1a

(Aliases: zgc:65886,fb78h12,LGIa,wu:fb78h12)

lgi1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 353 0.260
Mouse
neuron development GO:0048666 262 0.235
Mouse
signal transduction GO:0007165 455 0.234
larval development GO:0002164 2 0.174
regulation of multicellular organismal development GO:2000026 223 0.172
central nervous system development GO:0007417 387 0.169
organelle organization GO:0006996 227 0.168
brain development GO:0007420 293 0.160
cell projection organization GO:0030030 284 0.159
head development GO:0060322 303 0.140
generation of neurons GO:0048699 385 0.132
Mouse
organic substance biosynthetic process GO:1901576 289 0.132
cellular aromatic compound metabolic process GO:0006725 295 0.125
regulation of multicellular organismal process GO:0051239 277 0.118
regulation of developmental process GO:0050793 247 0.114
regulation of gene expression GO:0010468 265 0.092
embryo development ending in birth or egg hatching GO:0009792 271 0.088
cell projection morphogenesis GO:0048858 244 0.085
action potential GO:0001508 19 0.080
response to chemical GO:0042221 320 0.078
regulation of rna biosynthetic process GO:2001141 213 0.076
aromatic compound biosynthetic process GO:0019438 217 0.074
regulation of synapse assembly GO:0051963 3 0.073
regulation of dendrite development GO:0050773 3 0.069
regulation of nucleic acid templated transcription GO:1903506 213 0.068
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
transmembrane transport GO:0055085 120 0.064
regulation of nitrogen compound metabolic process GO:0051171 251 0.061
single organism localization GO:1902578 225 0.061
multicellular organismal signaling GO:0035637 22 0.059
cell part morphogenesis GO:0032990 246 0.058
neuronal action potential GO:0019228 18 0.056
nucleobase containing compound metabolic process GO:0006139 274 0.056
growth GO:0040007 174 0.056
locomotion GO:0040011 313 0.055
cellular biosynthetic process GO:0044249 286 0.055
establishment of localization GO:0051234 244 0.053
regulation of synapse organization GO:0050807 3 0.053
ion transport GO:0006811 114 0.050
regulation of biological quality GO:0065008 263 0.050
regulation of multicellular organism growth GO:0040014 4 0.049
transcription from rna polymerase ii promoter GO:0006366 80 0.048
regulation of cell substrate adhesion GO:0010810 1 0.048
positive regulation of developmental process GO:0051094 50 0.047
system process GO:0003008 185 0.047
embryonic organ development GO:0048568 381 0.047
regulation of cellular component organization GO:0051128 86 0.046
transcription dna templated GO:0006351 181 0.045
response to abiotic stimulus GO:0009628 122 0.045
gene expression GO:0010467 252 0.044
rna biosynthetic process GO:0032774 181 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.044
retina development in camera type eye GO:0060041 146 0.043
transmission of nerve impulse GO:0019226 19 0.043
cell matrix adhesion GO:0007160 4 0.043
axon development GO:0061564 166 0.043
cellular nitrogen compound metabolic process GO:0034641 290 0.042
hormone transport GO:0009914 2 0.041
ensheathment of neurons GO:0007272 18 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.041
synaptic growth at neuromuscular junction GO:0051124 2 0.040
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
regulation of gtp catabolic process GO:0033124 2 0.040
multicellular organism growth GO:0035264 4 0.040
guanosine containing compound metabolic process GO:1901068 4 0.040
wnt signaling pathway GO:0016055 80 0.039
heterocycle metabolic process GO:0046483 290 0.038
oxoacid metabolic process GO:0043436 31 0.038
negative regulation of biological process GO:0048519 304 0.037
response to external stimulus GO:0009605 264 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
nitrogen compound metabolic process GO:0006807 319 0.035
camera type eye development GO:0043010 222 0.034
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
negative regulation of cellular process GO:0048523 283 0.033
regulation of nucleotide catabolic process GO:0030811 2 0.032
heterocycle biosynthetic process GO:0018130 215 0.032
peripheral nervous system neuron differentiation GO:0048934 28 0.032
regulation of cell matrix adhesion GO:0001952 1 0.032
retina morphogenesis in camera type eye GO:0060042 79 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
myelination in peripheral nervous system GO:0022011 4 0.031
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
stem cell proliferation GO:0072089 4 0.030
regulation of cell differentiation GO:0045595 142 0.030
brain morphogenesis GO:0048854 18 0.030
Zebrafish
taxis GO:0042330 109 0.030
phagocytosis GO:0006909 3 0.030
regulation of transcription dna templated GO:0006355 213 0.029
regulation of mitochondrion organization GO:0010821 1 0.029
positive regulation of transport GO:0051050 2 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
response to drug GO:0042493 3 0.028
rna metabolic process GO:0016070 219 0.028
regulation of signal transduction GO:0009966 225 0.028
embryonic hemopoiesis GO:0035162 53 0.027
positive regulation of biological process GO:0048518 253 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
neuron projection morphogenesis GO:0048812 161 0.027
actin cytoskeleton organization GO:0030036 63 0.026
regulation of biosynthetic process GO:0009889 250 0.026
peripheral nervous system development GO:0007422 55 0.026
Mouse
anterior posterior pattern specification GO:0009952 152 0.026
homeostatic process GO:0042592 142 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
regulation of cell projection organization GO:0031344 44 0.026
organic acid metabolic process GO:0006082 31 0.025
regulation of fatty acid metabolic process GO:0019217 1 0.025
cytoskeleton organization GO:0007010 96 0.025
regulation of membrane potential GO:0042391 23 0.025
myotube differentiation GO:0014902 45 0.025
axonogenesis GO:0007409 152 0.025
meiotic nuclear division GO:0007126 4 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
single organism organelle organization GO:1902589 199 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
cell migration GO:0016477 237 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
mitochondrion organization GO:0007005 4 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
myelination GO:0042552 18 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
nucleic acid metabolic process GO:0090304 244 0.022
primitive hemopoiesis GO:0060215 27 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
camera type eye morphogenesis GO:0048593 108 0.022
negative regulation of metabolic process GO:0009892 86 0.022
positive regulation of multicellular organismal process GO:0051240 52 0.022
myeloid cell homeostasis GO:0002262 56 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.021
innervation GO:0060384 3 0.021
neuroblast proliferation GO:0007405 2 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
neuron projection development GO:0031175 180 0.021
regulation of signaling GO:0023051 235 0.021
localization of cell GO:0051674 244 0.021
axon guidance GO:0007411 86 0.021
olfactory bulb development GO:0021772 4 0.021
septum transversum development GO:0003343 4 0.021
guanosine containing compound catabolic process GO:1901069 2 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
cell motility GO:0048870 244 0.020
regulation of filopodium assembly GO:0051489 2 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
adherens junction organization GO:0034332 4 0.019
regulation of neurogenesis GO:0050767 87 0.019
gtp catabolic process GO:0006184 2 0.019
female sex differentiation GO:0046660 4 0.019
regulation of response to stimulus GO:0048583 269 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
peripheral nervous system neuron development GO:0048935 22 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
neurological system process GO:0050877 62 0.019
apoptotic process GO:0006915 116 0.018
aging GO:0007568 2 0.018
regulation of primary metabolic process GO:0080090 311 0.018
biosynthetic process GO:0009058 294 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
positive regulation of metabolic process GO:0009893 108 0.018
homeostasis of number of cells GO:0048872 62 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
cellular ketone metabolic process GO:0042180 11 0.018
macromolecule localization GO:0033036 54 0.018
regulation of dendrite morphogenesis GO:0048814 3 0.018
regulation of rna metabolic process GO:0051252 224 0.018
regulation of neuron projection development GO:0010975 40 0.018
small molecule metabolic process GO:0044281 77 0.018
actin filament based process GO:0030029 64 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.017
nuclear transport GO:0051169 4 0.017
regulation of cell morphogenesis GO:0022604 42 0.017
cellular component morphogenesis GO:0032989 336 0.017
myotube cell development GO:0014904 35 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
neuron projection regeneration GO:0031102 16 0.017
cellular component movement GO:0006928 335 0.017
positive regulation of gene expression GO:0010628 71 0.017
mitotic cell cycle embryonic GO:0045448 2 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
cellular component biogenesis GO:0044085 178 0.016
erythrocyte homeostasis GO:0034101 55 0.016
meiotic cell cycle process GO:1903046 3 0.016
regulation of metabolic process GO:0019222 359 0.016
pigmentation GO:0043473 85 0.016
cellular component assembly GO:0022607 170 0.016
regulation of cell development GO:0060284 100 0.016
response to vitamin GO:0033273 3 0.016
spinal cord development GO:0021510 46 0.016
cellular localization GO:0051641 97 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
organic substance transport GO:0071702 58 0.015
primary neural tube formation GO:0014020 1 0.015
neuromast development GO:0048884 46 0.015
locomotor rhythm GO:0045475 3 0.015
immune system process GO:0002376 241 0.015
programmed cell death GO:0012501 119 0.015
protein acetylation GO:0006473 2 0.015
maintenance of location GO:0051235 4 0.015
regulation of gtpase activity GO:0043087 2 0.015
polarized epithelial cell differentiation GO:0030859 4 0.015
gtp metabolic process GO:0046039 4 0.015
myeloid cell differentiation GO:0030099 86 0.014
cellular protein modification process GO:0006464 100 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
positive regulation of neuron death GO:1901216 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
cell aging GO:0007569 2 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
embryonic heart tube development GO:0035050 133 0.014
chemotaxis GO:0006935 104 0.014
regulation of cytokine production GO:0001817 3 0.014
optic nerve development GO:0021554 15 0.014
cell substrate junction assembly GO:0007044 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
response to organic substance GO:0010033 153 0.013
regulation of binding GO:0051098 3 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
nucleic acid templated transcription GO:0097659 181 0.013
phosphorus metabolic process GO:0006793 109 0.013
nuclear migration GO:0007097 3 0.013
response to nutrient GO:0007584 3 0.013
autophagy GO:0006914 4 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
death GO:0016265 121 0.013
adherens junction assembly GO:0034333 1 0.013
establishment of localization in cell GO:0051649 77 0.013
morphogenesis of an epithelial fold GO:0060571 1 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
transport GO:0006810 220 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
regulation of nervous system development GO:0051960 90 0.012
response to wounding GO:0009611 116 0.012
regulation of localization GO:0032879 104 0.012
locomotory behavior GO:0007626 34 0.012
regulation of protein targeting GO:1903533 2 0.012
cell morphogenesis GO:0000902 289 0.012
response to amino acid GO:0043200 2 0.012
hormone secretion GO:0046879 2 0.012
positive regulation of catabolic process GO:0009896 4 0.012
neuron projection guidance GO:0097485 86 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
protein metabolic process GO:0019538 183 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
cell substrate adherens junction assembly GO:0007045 1 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
regulation of catalytic activity GO:0050790 55 0.012
skeletal muscle fiber development GO:0048741 35 0.012
sensory organ development GO:0007423 393 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of cell shape GO:0008360 1 0.012
pharyngeal muscle development GO:0043282 4 0.012
negative regulation of cell development GO:0010721 26 0.012
microtubule based movement GO:0007018 33 0.012
angiogenesis GO:0001525 158 0.011
developmental growth GO:0048589 166 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
ossification GO:0001503 23 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
photoreceptor cell fate commitment GO:0046552 1 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
proepicardium development GO:0003342 4 0.011
glial cell proliferation GO:0014009 4 0.011
Mouse
cell proliferation in hindbrain GO:0021534 4 0.011
cellular response to estrogen stimulus GO:0071391 24 0.011
regulation of cell activation GO:0050865 1 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
renal absorption GO:0070293 1 0.011
peptide transport GO:0015833 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
response to axon injury GO:0048678 14 0.011
protein localization GO:0008104 40 0.011
posttranscriptional regulation of gene expression GO:0010608 14 0.011
response to stress GO:0006950 263 0.011
amine metabolic process GO:0009308 2 0.011
photoreceptor cell fate specification GO:0043704 1 0.011
developmental maturation GO:0021700 34 0.011
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of protein transport GO:0051223 3 0.010
stem cell division GO:0017145 1 0.010
neural retina development GO:0003407 49 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
cardiac cell fate commitment GO:0060911 1 0.010
regulation of bone mineralization GO:0030500 2 0.010
nerve development GO:0021675 45 0.010
regulation of cell projection assembly GO:0060491 4 0.010
regulation of apoptotic process GO:0042981 98 0.010

lgi1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016
congenital nervous system abnormality DOID:2490 0 0.015
physical disorder DOID:0080015 0 0.015