Danio rerio

74 known processes

lhx2b

LIM homeobox 2b

(Aliases: lhx2,zgc:152707,bel,MGC152707)

lhx2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retinal ganglion cell axon guidance GO:0031290 35 1.000
anterior posterior axon guidance GO:0033564 5 1.000
neuron projection guidance GO:0097485 86 0.999
diencephalon development GO:0021536 58 0.999
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.999
forebrain neuron development GO:0021884 7 0.999
cell part morphogenesis GO:0032990 246 0.998
neuron differentiation GO:0030182 353 0.997
generation of neurons GO:0048699 385 0.995
neuron development GO:0048666 262 0.993
neuron projection morphogenesis GO:0048812 161 0.993
forebrain development GO:0030900 96 0.991
cell morphogenesis involved in differentiation GO:0000904 195 0.989
neuron projection development GO:0031175 180 0.989
axon extension GO:0048675 45 0.988
Zebrafish Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.988
chemotaxis GO:0006935 104 0.986
negative regulation of axon guidance GO:1902668 1 0.986
axon development GO:0061564 166 0.984
positive regulation of cellular process GO:0048522 201 0.981
Mouse
central nervous system neuron differentiation GO:0021953 74 0.980
Zebrafish
neuron recognition GO:0008038 18 0.980
axon guidance GO:0007411 86 0.972
camera type eye morphogenesis GO:0048593 108 0.970
Zebrafish
cell projection morphogenesis GO:0048858 244 0.970
embryonic camera type eye development GO:0031076 29 0.970
Zebrafish
regulation of axonogenesis GO:0050770 32 0.969
taxis GO:0042330 109 0.950
negative regulation of axon extension GO:0030517 7 0.947
axonogenesis GO:0007409 152 0.941
pronephric glomerulus development GO:0039021 13 0.939
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.935
mesoderm development GO:0007498 88 0.921
Mouse
embryonic camera type eye morphogenesis GO:0048596 19 0.919
Zebrafish
eye morphogenesis GO:0048592 144 0.917
Zebrafish
regulation of developmental process GO:0050793 247 0.910
cell morphogenesis GO:0000902 289 0.907
head development GO:0060322 303 0.902
forebrain cell migration GO:0021885 1 0.899
regulation of axon extension GO:0030516 24 0.898
sensory organ morphogenesis GO:0090596 200 0.891
Zebrafish
forebrain generation of neurons GO:0021872 14 0.875
regulation of axon guidance GO:1902667 8 0.870
regulation of neuron differentiation GO:0045664 56 0.867
developmental cell growth GO:0048588 52 0.859
Zebrafish Mouse
commissural neuron axon guidance GO:0071679 3 0.852
olfactory bulb development GO:0021772 4 0.848
Mouse
cellular component morphogenesis GO:0032989 336 0.844
regulation of cell differentiation GO:0045595 142 0.837
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.824
Mouse
axon midline choice point recognition GO:0016199 4 0.822
cell fate commitment GO:0045165 99 0.822
Zebrafish
cellular component movement GO:0006928 335 0.811
regulation of organ growth GO:0046620 3 0.806
pronephros development GO:0048793 69 0.803
Zebrafish
regulation of cell morphogenesis GO:0022604 42 0.798
embryonic organ morphogenesis GO:0048562 274 0.794
Zebrafish
camera type eye development GO:0043010 222 0.790
transcription dna templated GO:0006351 181 0.787
Mouse
biosynthetic process GO:0009058 294 0.779
Mouse
habenula development GO:0021986 9 0.765
gland development GO:0048732 143 0.761
sensory organ development GO:0007423 393 0.758
system process GO:0003008 185 0.756
Zebrafish
optic nerve development GO:0021554 15 0.745
cellular biosynthetic process GO:0044249 286 0.744
Mouse
negative regulation of axonogenesis GO:0050771 7 0.741
central nervous system neuron development GO:0021954 29 0.730
brain morphogenesis GO:0048854 18 0.724
glial cell migration GO:0008347 3 0.720
neuron projection extension GO:1990138 45 0.720
Zebrafish Mouse
ventral spinal cord development GO:0021517 35 0.718
Zebrafish
tube morphogenesis GO:0035239 349 0.716
Zebrafish Mouse
morphogenesis of an epithelial sheet GO:0002011 49 0.715
Zebrafish
limbic system development GO:0021761 16 0.695
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.690
regulation of biosynthetic process GO:0009889 250 0.689
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.687
Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.684
cell projection organization GO:0030030 284 0.680
cell surface receptor signaling pathway GO:0007166 325 0.678
regulation of signal transduction GO:0009966 225 0.677
spinal cord development GO:0021510 46 0.676
Zebrafish
regulation of cell development GO:0060284 100 0.675
larval development GO:0002164 2 0.672
axon choice point recognition GO:0016198 5 0.665
growth GO:0040007 174 0.664
Zebrafish Mouse
regulation of synapse organization GO:0050807 3 0.660
regulation of multicellular organismal development GO:2000026 223 0.652
behavior GO:0007610 74 0.607
response to chemical GO:0042221 320 0.603
smoothened signaling pathway GO:0007224 30 0.597
negative regulation of chemotaxis GO:0050922 4 0.594
immune system development GO:0002520 191 0.590
aromatic compound biosynthetic process GO:0019438 217 0.582
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.574
auditory receptor cell differentiation GO:0042491 15 0.571
Zebrafish
urogenital system development GO:0001655 97 0.566
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.560
cardiocyte differentiation GO:0035051 44 0.557
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.555
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.546
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.544
Mouse
cell proliferation in forebrain GO:0021846 3 0.538
negative regulation of cell projection organization GO:0031345 9 0.535
post anal tail morphogenesis GO:0036342 19 0.534
heterocycle biosynthetic process GO:0018130 215 0.532
Mouse
brain development GO:0007420 293 0.529
embryonic camera type eye formation GO:0060900 10 0.528
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.527
Mouse
regulation of cell growth GO:0001558 29 0.527
cell recognition GO:0008037 19 0.522
glycosaminoglycan biosynthetic process GO:0006024 8 0.522
olfactory lobe development GO:0021988 4 0.515
Mouse
central nervous system development GO:0007417 387 0.510
regulation of synapse assembly GO:0051963 3 0.508
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.505
Zebrafish
type b pancreatic cell development GO:0003323 4 0.499
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.495
kidney development GO:0001822 92 0.491
Zebrafish
regulation of smoothened signaling pathway GO:0008589 18 0.488
regulation of nervous system development GO:0051960 90 0.484
semicircular canal development GO:0060872 24 0.484
Zebrafish
neural tube development GO:0021915 62 0.484
Zebrafish Mouse
hindbrain development GO:0030902 91 0.481
Zebrafish
regionalization GO:0003002 274 0.480
Zebrafish Mouse
synaptic target recognition GO:0008039 1 0.480
endocardium development GO:0003157 9 0.463
regulation of nucleic acid templated transcription GO:1903506 213 0.463
Mouse
thalamus development GO:0021794 6 0.462
morphogenesis of embryonic epithelium GO:0016331 30 0.448
Zebrafish Mouse
regulation of cell projection organization GO:0031344 44 0.440
negative regulation of cellular process GO:0048523 283 0.437
central nervous system projection neuron axonogenesis GO:0021952 15 0.432
response to wounding GO:0009611 116 0.431
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.422
forebrain regionalization GO:0021871 4 0.417
Mouse
motor neuron axon guidance GO:0008045 23 0.416
neuron fate commitment GO:0048663 26 0.413
Zebrafish
developmental growth GO:0048589 166 0.408
Zebrafish Mouse
localization of cell GO:0051674 244 0.407
regulation of metabolic process GO:0019222 359 0.405
renal system development GO:0072001 94 0.401
Zebrafish
post embryonic organ development GO:0048569 4 0.401
signal transduction GO:0007165 455 0.400
regulation of epithelial to mesenchymal transition GO:0010717 3 0.399
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.398
mesenchymal cell proliferation GO:0010463 1 0.397
cell differentiation in spinal cord GO:0021515 40 0.395
Zebrafish
retina development in camera type eye GO:0060041 146 0.393
Zebrafish Mouse
central nervous system neuron axonogenesis GO:0021955 18 0.389
cardioblast differentiation GO:0010002 9 0.387
response to external stimulus GO:0009605 264 0.387
pronephric glomerulus morphogenesis GO:0035775 6 0.384
Zebrafish
negative regulation of developmental growth GO:0048640 9 0.383
neuroblast proliferation GO:0007405 2 0.380
eye development GO:0001654 277 0.377
organic substance biosynthetic process GO:1901576 289 0.370
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.370
Zebrafish Mouse
regulation of axon extension involved in axon guidance GO:0048841 6 0.355
cell growth GO:0016049 57 0.354
Zebrafish Mouse
forebrain anterior posterior pattern specification GO:0021797 3 0.353
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.352
spinal cord motor neuron differentiation GO:0021522 26 0.350
Zebrafish
negative regulation of synapse assembly GO:0051964 2 0.349
regulation of cell communication GO:0010646 232 0.347
nucleic acid metabolic process GO:0090304 244 0.341
Mouse
regulation of extent of cell growth GO:0061387 29 0.339
cell motility GO:0048870 244 0.339
gabaergic neuron differentiation GO:0097154 2 0.337
Zebrafish
heparan sulfate proteoglycan biosynthetic process GO:0015012 5 0.336
negative regulation of multicellular organismal process GO:0051241 69 0.332
regulation of cellular component organization GO:0051128 86 0.331
forebrain neuron fate commitment GO:0021877 1 0.318
cell cell signaling involved in cell fate commitment GO:0045168 12 0.311
regulation of growth GO:0040008 42 0.309
regulation of signaling GO:0023051 235 0.307
heterocycle metabolic process GO:0046483 290 0.306
Mouse
transport GO:0006810 220 0.302
inner ear development GO:0048839 126 0.299
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.295
stem cell development GO:0048864 82 0.290
regulation of neurogenesis GO:0050767 87 0.287
digestive tract development GO:0048565 265 0.286
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.286
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.283
retina morphogenesis in camera type eye GO:0060042 79 0.281
regulation of neuron projection development GO:0010975 40 0.278
regulation of cell size GO:0008361 29 0.277
protein localization to nucleus GO:0034504 3 0.276
embryonic eye morphogenesis GO:0048048 30 0.276
Zebrafish
telencephalon development GO:0021537 14 0.275
cellular aromatic compound metabolic process GO:0006725 295 0.273
Mouse
regulation of organ morphogenesis GO:2000027 35 0.267
positive regulation of response to stimulus GO:0048584 80 0.264
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.263
auditory receptor cell fate determination GO:0042668 2 0.259
closure of optic fissure GO:0061386 6 0.257
Zebrafish
retina layer formation GO:0010842 24 0.257
regulation of anatomical structure morphogenesis GO:0022603 130 0.255
cell death GO:0008219 121 0.254
gastrulation GO:0007369 208 0.252
epithalamus development GO:0021538 10 0.252
single organismal cell cell adhesion GO:0016337 29 0.247
nitrogen compound metabolic process GO:0006807 319 0.246
Mouse
nephron development GO:0072006 31 0.244
Zebrafish
glomerulus development GO:0032835 27 0.240
Zebrafish
sensory neuron axon guidance GO:0097374 3 0.239
regulation of cellular component size GO:0032535 30 0.237
nerve development GO:0021675 45 0.235
neuron neuron synaptic transmission GO:0007270 1 0.230
hemopoiesis GO:0030097 183 0.230
positive regulation of cell cycle GO:0045787 3 0.228
hypothalamus development GO:0021854 14 0.228
stem cell proliferation GO:0072089 4 0.225
embryonic organ development GO:0048568 381 0.223
Zebrafish
artery development GO:0060840 22 0.217
axon extension involved in axon guidance GO:0048846 10 0.211
mesenchyme development GO:0060485 127 0.211
positive regulation of muscle organ development GO:0048636 1 0.211
pronephric nephron development GO:0039019 14 0.207
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.207
organic acid metabolic process GO:0006082 31 0.205
negative regulation of signaling GO:0023057 96 0.205
extrinsic apoptotic signaling pathway GO:0097191 3 0.205
mesenchyme morphogenesis GO:0072132 5 0.204
response to stress GO:0006950 263 0.201
atrial ventricular junction remodeling GO:0003294 2 0.201
epithelial tube morphogenesis GO:0060562 148 0.200
Mouse
germ cell migration GO:0008354 8 0.200
regulation of macromolecule metabolic process GO:0060255 317 0.197
pancreatic d cell development GO:0003324 1 0.196
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.194
Mouse
neural plate development GO:0001840 10 0.194
blood vessel development GO:0001568 246 0.193
negative chemotaxis GO:0050919 1 0.191
transmission of nerve impulse GO:0019226 19 0.191
forebrain morphogenesis GO:0048853 6 0.190
organelle organization GO:0006996 227 0.189
fourth ventricle development GO:0021592 8 0.189
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.188
Mouse
otolith development GO:0048840 32 0.187
Zebrafish
regulation of dendrite morphogenesis GO:0048814 3 0.181
regulation of multicellular organismal process GO:0051239 277 0.179
Zebrafish
developmental programmed cell death GO:0010623 4 0.178
regulation of heart growth GO:0060420 2 0.178
mesoderm formation GO:0001707 43 0.173
regulation of locomotion GO:0040012 55 0.173
heparan sulfate proteoglycan metabolic process GO:0030201 6 0.171
locomotion GO:0040011 313 0.171
protein metabolic process GO:0019538 183 0.170
apoptotic process GO:0006915 116 0.166
regulation of chemotaxis GO:0050920 18 0.163
rna biosynthetic process GO:0032774 181 0.163
Mouse
negative regulation of cellular component movement GO:0051271 18 0.162
olfactory placode development GO:0071698 12 0.158
embryonic limb morphogenesis GO:0030326 2 0.157
endocrine system development GO:0035270 65 0.157
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.156
Mouse
cell substrate adhesion GO:0031589 4 0.155
negative regulation of neuron projection development GO:0010977 9 0.154
tissue regeneration GO:0042246 74 0.150
digestive tract morphogenesis GO:0048546 231 0.149
regulation of dendrite development GO:0050773 3 0.149
stem cell maintenance GO:0019827 4 0.148
negative regulation of nervous system development GO:0051961 22 0.148
camera type eye photoreceptor cell differentiation GO:0060219 19 0.145
swimming behavior GO:0036269 8 0.144
positive regulation of gene expression GO:0010628 71 0.143
Mouse
regulation of neurological system process GO:0031644 2 0.143
auditory receptor cell fate commitment GO:0009912 4 0.141
phagocytosis GO:0006909 3 0.140
formation of primary germ layer GO:0001704 62 0.140
gastrulation with mouth forming second GO:0001702 44 0.140
nucleobase containing compound metabolic process GO:0006139 274 0.138
Mouse
positive regulation of map kinase activity GO:0043406 3 0.138
embryonic appendage morphogenesis GO:0035113 30 0.137
organic cyclic compound biosynthetic process GO:1901362 223 0.137
Mouse
cardiac cell fate commitment GO:0060911 1 0.137
negative regulation of cellular biosynthetic process GO:0031327 55 0.135
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.135
rhombomere development GO:0021546 19 0.133
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.131
hematopoietic or lymphoid organ development GO:0048534 191 0.130
indole containing compound metabolic process GO:0042430 2 0.130
patterning of blood vessels GO:0001569 15 0.128
regulation of developmental growth GO:0048638 38 0.127
optomotor response GO:0071632 1 0.127
hepatocyte proliferation GO:0072574 2 0.127
exocrine system development GO:0035272 28 0.126
Zebrafish
establishment of organelle localization GO:0051656 45 0.126
death GO:0016265 121 0.124
cell fate specification GO:0001708 68 0.123
Zebrafish
regulation of collateral sprouting in absence of injury GO:0048696 4 0.122
axonal fasciculation GO:0007413 11 0.121
regulation of stem cell proliferation GO:0072091 2 0.121
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.120
striated muscle tissue development GO:0014706 110 0.120
Zebrafish
cell proliferation in midbrain GO:0033278 4 0.119
regulation of protein import into nucleus GO:0042306 2 0.119
regulation of anatomical structure size GO:0090066 33 0.119
biological adhesion GO:0022610 40 0.119
ovulation cycle process GO:0022602 2 0.118
dendrite guidance GO:0070983 0 0.118
dendrite development GO:0016358 9 0.118
inner ear receptor cell fate commitment GO:0060120 4 0.118
apoptotic signaling pathway GO:0097190 23 0.117
regulation of cellular response to growth factor stimulus GO:0090287 35 0.117
odontogenesis of dentin containing tooth GO:0042475 1 0.117
muscle cell differentiation GO:0042692 139 0.116
Zebrafish
positive regulation of endothelial cell differentiation GO:0045603 2 0.115
heart looping GO:0001947 94 0.112
cilium morphogenesis GO:0060271 85 0.111
ventral spinal cord interneuron specification GO:0021521 3 0.111
formation of anatomical boundary GO:0048859 14 0.110
tube formation GO:0035148 25 0.109
Mouse
digestive system development GO:0055123 289 0.109
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.108
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.108
activation of mapk activity GO:0000187 3 0.107
angiogenesis GO:0001525 158 0.107
sequestering of metal ion GO:0051238 3 0.107
intracellular signal transduction GO:0035556 85 0.106
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.105
negative regulation of biological process GO:0048519 304 0.105
cell adhesion GO:0007155 40 0.105
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.105
cell proliferation in dorsal spinal cord GO:0010456 2 0.104
homeostatic process GO:0042592 142 0.104
odontogenesis GO:0042476 9 0.104
phosphate containing compound metabolic process GO:0006796 108 0.104
paraxial mesoderm morphogenesis GO:0048340 2 0.103
establishment of localization GO:0051234 244 0.102
muscle cell development GO:0055001 115 0.101
single organism nuclear import GO:1902593 3 0.100
lateral inhibition GO:0046331 1 0.099
catechol containing compound biosynthetic process GO:0009713 2 0.099
anatomical structure homeostasis GO:0060249 36 0.099
lateral line development GO:0048882 66 0.099
cranial nerve development GO:0021545 42 0.098
negative regulation of wnt signaling pathway GO:0030178 30 0.097
signal transduction in absence of ligand GO:0038034 1 0.096
positive regulation of signaling GO:0023056 56 0.096
canonical wnt signaling pathway GO:0060070 48 0.096
dorsal ventral axis specification GO:0009950 14 0.096
rna metabolic process GO:0016070 219 0.095
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.094
mechanoreceptor differentiation GO:0042490 37 0.093
Zebrafish
negative regulation of cell motility GO:2000146 17 0.092
cardiac muscle tissue development GO:0048738 48 0.091
Zebrafish
negative regulation of cell growth GO:0030308 7 0.091
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.090
cellular nitrogen compound metabolic process GO:0034641 290 0.090
Mouse
hypothalamus cell differentiation GO:0021979 4 0.089
mesenchymal cell development GO:0014031 78 0.089
dorsal ventral pattern formation GO:0009953 125 0.088
Mouse
somitogenesis GO:0001756 87 0.088
regulation of system process GO:0044057 40 0.087
Zebrafish
regulation of localization GO:0032879 104 0.087
erk1 and erk2 cascade GO:0070371 4 0.086
cell cycle GO:0007049 93 0.086
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.086
phenol containing compound biosynthetic process GO:0046189 4 0.085
visual behavior GO:0007632 10 0.085
peripheral nervous system development GO:0007422 55 0.085
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.084
mucopolysaccharide metabolic process GO:1903510 2 0.084
protein import GO:0017038 3 0.084
proximal distal pattern formation GO:0009954 1 0.083
regulation of rna biosynthetic process GO:2001141 213 0.082
Mouse
regulation of rna metabolic process GO:0051252 224 0.081
Mouse
adenohypophysis development GO:0021984 15 0.081
convergent extension GO:0060026 118 0.080
catecholamine biosynthetic process GO:0042423 2 0.079
negative regulation of cellular component organization GO:0051129 16 0.079
organelle assembly GO:0070925 110 0.078
neuron fate specification GO:0048665 20 0.078
Zebrafish
cell migration GO:0016477 237 0.078
positive regulation of nucleic acid templated transcription GO:1903508 57 0.077
Mouse
outflow tract morphogenesis GO:0003151 1 0.076
regulation of mesenchymal cell proliferation GO:0010464 1 0.076
multicellular organismal reproductive process GO:0048609 35 0.075
regulation of canonical wnt signaling pathway GO:0060828 34 0.075
positive regulation of rac protein signal transduction GO:0035022 1 0.074
protein targeting to nucleus GO:0044744 3 0.074
neuron fate determination GO:0048664 2 0.073
regeneration GO:0031099 91 0.073
peripheral nervous system neuron development GO:0048935 22 0.073
Zebrafish
multi organism process GO:0051704 134 0.073
pancreatic d cell differentiation GO:0003311 2 0.072
Zebrafish
dopamine biosynthetic process GO:0042416 2 0.072
entrainment of circadian clock GO:0009649 2 0.072
diencephalon morphogenesis GO:0048852 5 0.071
neural crest cell development GO:0014032 62 0.071
positive regulation of macromolecule metabolic process GO:0010604 93 0.071
Mouse
pituitary gland development GO:0021983 16 0.070
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.070
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.070
Mouse
endocardium morphogenesis GO:0003160 4 0.070
embryonic skeletal system morphogenesis GO:0048704 93 0.070
neural retina development GO:0003407 49 0.069
blood vessel morphogenesis GO:0048514 216 0.067
positive regulation of cell death GO:0010942 29 0.067
optic placode formation involved in camera type eye formation GO:0046619 3 0.067
collateral sprouting in absence of injury GO:0048669 4 0.066
regulation of cytoplasmic transport GO:1903649 4 0.066
nucleocytoplasmic transport GO:0006913 4 0.065
pancreatic a cell development GO:0003322 2 0.065
Zebrafish
somatic stem cell maintenance GO:0035019 1 0.065
establishment of protein localization to organelle GO:0072594 4 0.065
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.065
positive regulation of rna biosynthetic process GO:1902680 57 0.065
Mouse
negative regulation of locomotion GO:0040013 18 0.064
regulation of wnt signaling pathway GO:0030111 53 0.063
developmental induction GO:0031128 10 0.063
positive regulation of bmp signaling pathway GO:0030513 10 0.062
dendrite morphogenesis GO:0048813 5 0.060
negative regulation of growth GO:0045926 10 0.060
regulation of cell fate commitment GO:0010453 22 0.059
single organism localization GO:1902578 225 0.058
ventral spinal cord interneuron fate commitment GO:0060579 3 0.058
endocardial cushion morphogenesis GO:0003203 3 0.058
response to fibroblast growth factor GO:0071774 22 0.058
neuron migration GO:0001764 22 0.058
ameboidal type cell migration GO:0001667 143 0.057
microtubule based process GO:0007017 60 0.056
positive regulation of transcription dna templated GO:0045893 57 0.056
Mouse
regulation of multicellular organism growth GO:0040014 4 0.056
cellular nitrogen compound biosynthetic process GO:0044271 218 0.056
Mouse
embryonic heart tube formation GO:0003144 1 0.056
otolith morphogenesis GO:0032474 8 0.056
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.056
morphogenesis of an epithelium GO:0002009 333 0.055
Zebrafish Mouse
regulation of phospholipase activity GO:0010517 2 0.055
positive regulation of biological process GO:0048518 253 0.055
Mouse
multicellular organism growth GO:0035264 4 0.055
cellular protein modification process GO:0006464 100 0.054
smooth muscle tissue development GO:0048745 1 0.054
epithelial to mesenchymal transition GO:0001837 21 0.054
lamellipodium assembly GO:0030032 1 0.054
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.053
modification dependent protein catabolic process GO:0019941 3 0.053
heart jogging GO:0003146 40 0.053
skin morphogenesis GO:0043589 7 0.053
embryonic heart tube development GO:0035050 133 0.052
regulation of synapse structure and activity GO:0050803 5 0.052
negative regulation of developmental process GO:0051093 65 0.052
endocrine pancreas development GO:0031018 27 0.052
Zebrafish
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.052
regulation of endodermal cell fate specification GO:0042663 15 0.052
regulation of stem cell differentiation GO:2000736 4 0.052
lamellipodium organization GO:0097581 1 0.052
vasculature development GO:0001944 278 0.052
regulation of cell cycle GO:0051726 52 0.051
female gonad development GO:0008585 4 0.051
cellular ketone metabolic process GO:0042180 11 0.050
brain segmentation GO:0035284 6 0.050
cell proliferation in hindbrain GO:0021534 4 0.049
regulation of cell shape GO:0008360 1 0.049
fin morphogenesis GO:0033334 53 0.049
negative regulation of metabolic process GO:0009892 86 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
Mouse
striated muscle cell differentiation GO:0051146 129 0.048
Zebrafish
amine metabolic process GO:0009308 2 0.048
regulation of cardiac muscle tissue development GO:0055024 1 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.047
regulation of retinoic acid biosynthetic process GO:1900052 6 0.046
positive regulation of neuron apoptotic process GO:0043525 1 0.046
cilium organization GO:0044782 71 0.046
programmed cell death GO:0012501 119 0.045
muscle cell migration GO:0014812 4 0.045
ventricular system development GO:0021591 12 0.045
Zebrafish
regulation of cell death GO:0010941 103 0.045
positive regulation of cell adhesion GO:0045785 1 0.045
macromolecule modification GO:0043412 111 0.045
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
regulation of cell matrix adhesion GO:0001952 1 0.045
positive regulation of stem cell proliferation GO:2000648 1 0.044
negative regulation of cell differentiation GO:0045596 46 0.044
post embryonic organ morphogenesis GO:0048563 1 0.044
regulation of cell migration GO:0030334 40 0.043
positive regulation of programmed cell death GO:0043068 29 0.043
organic substance catabolic process GO:1901575 28 0.043
muscle structure development GO:0061061 196 0.043
Zebrafish
stem cell differentiation GO:0048863 117 0.042
neural precursor cell proliferation GO:0061351 20 0.042
negative regulation of intracellular transport GO:0032387 3 0.042
negative regulation of protein kinase activity GO:0006469 4 0.042
inner ear receptor cell development GO:0060119 20 0.042
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.042
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
Mouse
branchiomotor neuron axon guidance GO:0021785 1 0.041
paraxial mesoderm development GO:0048339 8 0.041
morphogenesis of a branching structure GO:0001763 21 0.040
bmp signaling pathway GO:0030509 52 0.040

lhx2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
endocrine system disease DOID:28 0 0.044