Danio rerio

34 known processes

lingo1b

leucine rich repeat and Ig domain containing 1b

(Aliases: zgc:92338,lingo1)

lingo1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
astrocyte differentiation GO:0048708 1 0.514
generation of neurons GO:0048699 385 0.415
regionalization GO:0003002 274 0.412
sensory organ development GO:0007423 393 0.250
embryonic organ development GO:0048568 381 0.235
camera type eye development GO:0043010 222 0.226
regulation of cell differentiation GO:0045595 142 0.221
Mouse
forebrain development GO:0030900 96 0.208
central nervous system development GO:0007417 387 0.188
Mouse
positive regulation of cell cycle GO:0045787 3 0.168
regulation of nervous system development GO:0051960 90 0.152
Mouse
positive regulation of biological process GO:0048518 253 0.147
regulation of multicellular organismal development GO:2000026 223 0.135
Mouse
stem cell differentiation GO:0048863 117 0.133
neuron projection development GO:0031175 180 0.133
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.133
axon ensheathment in central nervous system GO:0032291 2 0.126
negative regulation of biological process GO:0048519 304 0.121
Mouse
eye development GO:0001654 277 0.114
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.111
regulation of oligodendrocyte differentiation GO:0048713 1 0.109
Mouse
neuron differentiation GO:0030182 353 0.107
cell projection morphogenesis GO:0048858 244 0.102
camera type eye morphogenesis GO:0048593 108 0.096
ameboidal type cell migration GO:0001667 143 0.096
inner ear development GO:0048839 126 0.096
oligodendrocyte differentiation GO:0048709 23 0.095
Mouse
primary neural tube formation GO:0014020 1 0.093
ear development GO:0043583 127 0.092
brain development GO:0007420 293 0.092
regulation of gtp catabolic process GO:0033124 2 0.090
regulation of neuron projection development GO:0010975 40 0.090
regulation of membrane potential GO:0042391 23 0.088
regulation of purine nucleotide catabolic process GO:0033121 2 0.081
cell surface receptor signaling pathway GO:0007166 325 0.081
signal transduction GO:0007165 455 0.081
Mouse
positive regulation of cell differentiation GO:0045597 30 0.080
regulation of cellular amino acid metabolic process GO:0006521 0 0.080
action potential GO:0001508 19 0.076
morphogenesis of embryonic epithelium GO:0016331 30 0.075
forebrain cell migration GO:0021885 1 0.074
head development GO:0060322 303 0.071
convergent extension GO:0060026 118 0.071
regulation of neurogenesis GO:0050767 87 0.070
Mouse
glial cell differentiation GO:0010001 42 0.069
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.067
larval development GO:0002164 2 0.065
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.065
eye morphogenesis GO:0048592 144 0.064
regulation of response to stimulus GO:0048583 269 0.062
organelle localization GO:0051640 49 0.061
enzyme linked receptor protein signaling pathway GO:0007167 106 0.061
regulation of cell development GO:0060284 100 0.061
Mouse
sensory organ morphogenesis GO:0090596 200 0.060
gtp catabolic process GO:0006184 2 0.060
determination of heart left right asymmetry GO:0061371 117 0.060
positive regulation of cell communication GO:0010647 56 0.059
central nervous system myelination GO:0022010 2 0.057
convergent extension involved in organogenesis GO:0060029 10 0.057
developmental growth involved in morphogenesis GO:0060560 86 0.057
regulation of developmental process GO:0050793 247 0.056
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.055
liver development GO:0001889 96 0.054
positive regulation of cellular catabolic process GO:0031331 3 0.053
regulation of metabolic process GO:0019222 359 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
Mouse
erk1 and erk2 cascade GO:0070371 4 0.050
cell fate specification GO:0001708 68 0.050
cell substrate adhesion GO:0031589 4 0.049
ectodermal placode development GO:0071696 37 0.048
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.048
embryonic organ morphogenesis GO:0048562 274 0.047
mesenchymal cell development GO:0014031 78 0.047
retina development in camera type eye GO:0060041 146 0.047
mesenchyme development GO:0060485 127 0.046
single organism metabolic process GO:0044710 217 0.046
negative regulation of cellular catabolic process GO:0031330 3 0.045
cell proliferation in hindbrain GO:0021534 4 0.045
cognition GO:0050890 1 0.045
regulation of glial cell differentiation GO:0045685 4 0.045
Mouse
positive regulation of response to stimulus GO:0048584 80 0.045
organic substance biosynthetic process GO:1901576 289 0.045
diencephalon development GO:0021536 58 0.044
skeletal system development GO:0001501 181 0.044
cell part morphogenesis GO:0032990 246 0.043
positive regulation of rac protein signal transduction GO:0035022 1 0.043
response to drug GO:0042493 3 0.043
neuromuscular process controlling balance GO:0050885 3 0.043
cardioblast migration GO:0003260 7 0.042
cell migration to the midline involved in heart development GO:0003318 12 0.042
carboxylic acid metabolic process GO:0019752 22 0.042
cell morphogenesis involved in differentiation GO:0000904 195 0.041
positive regulation of secretion by cell GO:1903532 1 0.041
amine metabolic process GO:0009308 2 0.041
cellular amino acid metabolic process GO:0006520 7 0.040
cell migration involved in heart formation GO:0060974 10 0.040
vasculogenesis GO:0001570 41 0.040
cellular component morphogenesis GO:0032989 336 0.040
blood vessel morphogenesis GO:0048514 216 0.040
tube morphogenesis GO:0035239 349 0.038
forebrain neuron fate commitment GO:0021877 1 0.038
axon ensheathment GO:0008366 18 0.038
cell migration involved in heart development GO:0060973 22 0.038
phagocytosis GO:0006909 3 0.037
vasculature development GO:0001944 278 0.037
brain morphogenesis GO:0048854 18 0.037
hindbrain development GO:0030902 91 0.036
cellular amine metabolic process GO:0044106 2 0.036
erythrocyte differentiation GO:0030218 54 0.035
cell morphogenesis GO:0000902 289 0.035
startle response GO:0001964 4 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.035
developmental cell growth GO:0048588 52 0.035
positive regulation of developmental process GO:0051094 50 0.034
regulation of axonogenesis GO:0050770 32 0.034
positive regulation of transport GO:0051050 2 0.034
single organism transport GO:0044765 206 0.034
endocrine process GO:0050886 2 0.034
positive regulation of secretion GO:0051047 1 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
positive regulation of metabolic process GO:0009893 108 0.033
mesenchymal cell differentiation GO:0048762 87 0.033
axon development GO:0061564 166 0.033
Zebrafish
mitotic cell cycle process GO:1903047 48 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.032
stem cell proliferation GO:0072089 4 0.032
axon extension GO:0048675 45 0.032
outflow tract morphogenesis GO:0003151 1 0.032
ectodermal placode morphogenesis GO:0071697 32 0.031
Zebrafish
axon guidance GO:0007411 86 0.031
skeletal system morphogenesis GO:0048705 102 0.030
blood vessel development GO:0001568 246 0.030
cellular macromolecule metabolic process GO:0044260 391 0.030
neuronal action potential GO:0019228 18 0.029
multicellular organism growth GO:0035264 4 0.029
gliogenesis GO:0042063 45 0.029
Mouse
apoptotic process GO:0006915 116 0.029
response to ketone GO:1901654 1 0.029
cell proliferation in forebrain GO:0021846 3 0.029
regeneration GO:0031099 91 0.029
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.029
cellular ketone metabolic process GO:0042180 11 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
gene expression GO:0010467 252 0.028
cellular biosynthetic process GO:0044249 286 0.028
positive regulation of cellular process GO:0048522 201 0.027
embryonic skeletal system development GO:0048706 97 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
oxoacid metabolic process GO:0043436 31 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
nephron epithelium morphogenesis GO:0072088 1 0.027
maintenance of location GO:0051235 4 0.027
heart development GO:0007507 313 0.027
specification of axis polarity GO:0065001 4 0.027
axonogenesis GO:0007409 152 0.026
cytoskeleton organization GO:0007010 96 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
heart morphogenesis GO:0003007 156 0.026
neuron projection morphogenesis GO:0048812 161 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
specification of symmetry GO:0009799 204 0.026
commissural neuron axon guidance GO:0071679 3 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
regulation of signaling GO:0023051 235 0.025
cell fate commitment GO:0045165 99 0.025
locomotion GO:0040011 313 0.025
digestive tract development GO:0048565 265 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.025
positive regulation of cell substrate adhesion GO:0010811 1 0.025
neuron development GO:0048666 262 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
locomotor rhythm GO:0045475 3 0.025
g1 s transition of mitotic cell cycle GO:0000082 1 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
positive regulation of catabolic process GO:0009896 4 0.024
stem cell development GO:0048864 82 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
mitotic cell cycle embryonic GO:0045448 2 0.023
adult behavior GO:0030534 2 0.023
hemopoiesis GO:0030097 183 0.023
neural crest cell development GO:0014032 62 0.023
regulation of wnt signaling pathway GO:0030111 53 0.023
anterior posterior axis specification GO:0009948 20 0.023
peripheral nervous system development GO:0007422 55 0.023
posterior lateral line neuromast development GO:0048919 20 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
embryonic cranial skeleton morphogenesis GO:0048701 90 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
negative regulation of catabolic process GO:0009895 3 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
proximal distal pattern formation GO:0009954 1 0.022
negative regulation of nervous system development GO:0051961 22 0.022
Mouse
regulation of biosynthetic process GO:0009889 250 0.022
transport GO:0006810 220 0.022
positive regulation of ras protein signal transduction GO:0046579 1 0.022
regulation of cell migration GO:0030334 40 0.021
negative regulation of axon guidance GO:1902668 1 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
synaptic target recognition GO:0008039 1 0.021
homeostatic process GO:0042592 142 0.021
forebrain regionalization GO:0021871 4 0.021
regulation of cell death GO:0010941 103 0.020
phosphorus metabolic process GO:0006793 109 0.020
regulation of cell communication GO:0010646 232 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
canonical wnt signaling pathway GO:0060070 48 0.020
gtp metabolic process GO:0046039 4 0.020
ensheathment of neurons GO:0007272 18 0.020
regulation of rac protein signal transduction GO:0035020 1 0.020
peptide transport GO:0015833 1 0.020
neural crest cell differentiation GO:0014033 72 0.019
negative regulation of gliogenesis GO:0014014 1 0.019
Mouse
regulation of protein complex assembly GO:0043254 3 0.019
regulation of hormone secretion GO:0046883 2 0.019
embryonic heart tube development GO:0035050 133 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.019
cell matrix adhesion GO:0007160 4 0.019
regulation of gtpase activity GO:0043087 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
cell death GO:0008219 121 0.019
epithelial cell differentiation GO:0030855 116 0.019
negative regulation of developmental process GO:0051093 65 0.019
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
positive regulation of cell matrix adhesion GO:0001954 1 0.019
neuron projection extension GO:1990138 45 0.019
immune system process GO:0002376 241 0.018
negative regulation of wnt signaling pathway GO:0030178 30 0.018
oligodendrocyte development GO:0014003 7 0.018
cell migration GO:0016477 237 0.018
epidermal cell differentiation GO:0009913 36 0.018
positive regulation of signal transduction GO:0009967 56 0.018
trigeminal nerve development GO:0021559 3 0.018
regulation of cellular component movement GO:0051270 55 0.018
cytokinesis GO:0000910 3 0.018
regulation of circadian rhythm GO:0042752 4 0.018
gastrulation GO:0007369 208 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
establishment of localization GO:0051234 244 0.017
olfactory bulb development GO:0021772 4 0.017
lipid catabolic process GO:0016042 4 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.017
cellular component biogenesis GO:0044085 178 0.017
immune system development GO:0002520 191 0.017
response to axon injury GO:0048678 14 0.017
Zebrafish
mrna polyadenylation GO:0006378 2 0.017
calcium ion transport into cytosol GO:0060402 3 0.017
hormone secretion GO:0046879 2 0.017
pituitary gland development GO:0021983 16 0.017
segmentation GO:0035282 97 0.017
phagocytosis engulfment GO:0006911 1 0.017
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.016
wnt signaling pathway GO:0016055 80 0.016
regulation of cell projection organization GO:0031344 44 0.016
single organism organelle organization GO:1902589 199 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of catalytic activity GO:0050790 55 0.016
death GO:0016265 121 0.016
multicellular organismal signaling GO:0035637 22 0.016
ear morphogenesis GO:0042471 64 0.016
cellular protein modification process GO:0006464 100 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.016
programmed cell death GO:0012501 119 0.016
cell projection organization GO:0030030 284 0.016
Zebrafish Mouse
protein import GO:0017038 3 0.016
cell proliferation in midbrain GO:0033278 4 0.016
regulation of cell cycle GO:0051726 52 0.016
urogenital system development GO:0001655 97 0.016
regulation of gene expression GO:0010468 265 0.016
neural tube formation GO:0001841 16 0.016
regulation of jak stat cascade GO:0046425 3 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.015
organic acid metabolic process GO:0006082 31 0.015
transcription dna templated GO:0006351 181 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
purine nucleotide metabolic process GO:0006163 27 0.015
metencephalon development GO:0022037 27 0.015
lateral line system development GO:0048925 76 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
Mouse
gland development GO:0048732 143 0.015
localization of cell GO:0051674 244 0.015
dopaminergic neuron differentiation GO:0071542 14 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
axis specification GO:0009798 43 0.015
otic vesicle development GO:0071599 42 0.014
determination of left right symmetry GO:0007368 179 0.014
small molecule metabolic process GO:0044281 77 0.014
entrainment of circadian clock GO:0009649 2 0.014
cellular component movement GO:0006928 335 0.014
axon midline choice point recognition GO:0016199 4 0.014
sympathetic nervous system development GO:0048485 3 0.014
regulation of mechanoreceptor differentiation GO:0045631 1 0.014
neuron remodeling GO:0016322 1 0.014
regulation of transporter activity GO:0032409 2 0.014
tyrosine phosphorylation of stat protein GO:0007260 1 0.014
sensory system development GO:0048880 76 0.014
regulation of reproductive process GO:2000241 4 0.014
negative regulation of cell development GO:0010721 26 0.014
Mouse
regulation of signal transduction GO:0009966 225 0.014
establishment of localization in cell GO:0051649 77 0.014
regulation of nucleotide metabolic process GO:0006140 17 0.014
regulation of dendrite development GO:0050773 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
response to monosaccharide GO:0034284 3 0.013
cellular component assembly GO:0022607 170 0.013
telencephalon development GO:0021537 14 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
central nervous system neuron development GO:0021954 29 0.013
Mouse
development of primary female sexual characteristics GO:0046545 4 0.013
response to carbohydrate GO:0009743 3 0.013
gabaergic neuron differentiation GO:0097154 2 0.013
somatic stem cell maintenance GO:0035019 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
inner ear receptor cell fate commitment GO:0060120 4 0.013
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.013
epithelial tube formation GO:0072175 19 0.013
neuroblast proliferation GO:0007405 2 0.013
regulation of purine nucleotide metabolic process GO:1900542 17 0.012
nucleic acid metabolic process GO:0090304 244 0.012
eye photoreceptor cell differentiation GO:0001754 45 0.012
developmental growth GO:0048589 166 0.012
rna biosynthetic process GO:0032774 181 0.012
glucose homeostasis GO:0042593 1 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
atp catabolic process GO:0006200 4 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of cell cycle g2 m phase transition GO:1902749 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.012
regulation of cell motility GO:2000145 46 0.012
carbohydrate homeostasis GO:0033500 1 0.012
fertilization GO:0009566 3 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
mechanoreceptor differentiation GO:0042490 37 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
extracellular structure organization GO:0043062 27 0.012
regulation of primary metabolic process GO:0080090 311 0.012
protein targeting to nucleus GO:0044744 3 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
nuclear export GO:0051168 1 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
positive regulation of cell development GO:0010720 25 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
regulation of neuron differentiation GO:0045664 56 0.011
dendrite guidance GO:0070983 0 0.011
inner ear morphogenesis GO:0042472 63 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
response to chemical GO:0042221 320 0.011
positive regulation of signaling GO:0023056 56 0.011
negative regulation of cellular process GO:0048523 283 0.011
Mouse
dorsal ventral pattern formation GO:0009953 125 0.011
stem cell maintenance GO:0019827 4 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
response to unfolded protein GO:0006986 2 0.011
myeloid cell differentiation GO:0030099 86 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cell adhesion GO:0007155 40 0.011
transmission of nerve impulse GO:0019226 19 0.011
neuron projection guidance GO:0097485 86 0.010
kidney development GO:0001822 92 0.010
olfactory lobe development GO:0021988 4 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
nuclear import GO:0051170 3 0.010
muscle cell differentiation GO:0042692 139 0.010
organism emergence from protective structure GO:0071684 4 0.010
response to amino acid GO:0043200 2 0.010
pons development GO:0021548 11 0.010
cell projection assembly GO:0030031 64 0.010
heart looping GO:0001947 94 0.010
negative regulation of gene expression GO:0010629 65 0.010
positive regulation of nervous system development GO:0051962 25 0.010
otic vesicle formation GO:0030916 27 0.010
nephron morphogenesis GO:0072028 2 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.010
response to organic substance GO:0010033 153 0.010

lingo1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.051
amyloidosis DOID:9120 0 0.051
acquired metabolic disease DOID:0060158 0 0.051