Danio rerio

34 known processes

lingo1b

leucine rich repeat and Ig domain containing 1b

(Aliases: zgc:92338,lingo1)

lingo1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
astrocyte differentiation GO:0048708 1 0.514
generation of neurons GO:0048699 385 0.415
regionalization GO:0003002 274 0.412
sensory organ development GO:0007423 393 0.250
embryonic organ development GO:0048568 381 0.235
camera type eye development GO:0043010 222 0.226
regulation of cell differentiation GO:0045595 142 0.221
Mouse
forebrain development GO:0030900 96 0.208
central nervous system development GO:0007417 387 0.188
Mouse
positive regulation of cell cycle GO:0045787 3 0.168
regulation of nervous system development GO:0051960 90 0.152
Mouse
positive regulation of biological process GO:0048518 253 0.147
regulation of multicellular organismal development GO:2000026 223 0.135
Mouse
stem cell differentiation GO:0048863 117 0.133
neuron projection development GO:0031175 180 0.133
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.133
axon ensheathment in central nervous system GO:0032291 2 0.126
negative regulation of biological process GO:0048519 304 0.121
Mouse
eye development GO:0001654 277 0.114
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.111
regulation of oligodendrocyte differentiation GO:0048713 1 0.109
Mouse
neuron differentiation GO:0030182 353 0.107
cell projection morphogenesis GO:0048858 244 0.102
camera type eye morphogenesis GO:0048593 108 0.096
ameboidal type cell migration GO:0001667 143 0.096
inner ear development GO:0048839 126 0.096
oligodendrocyte differentiation GO:0048709 23 0.095
Mouse
primary neural tube formation GO:0014020 1 0.093
ear development GO:0043583 127 0.092
brain development GO:0007420 293 0.092
regulation of gtp catabolic process GO:0033124 2 0.090
regulation of neuron projection development GO:0010975 40 0.090
regulation of membrane potential GO:0042391 23 0.088
regulation of purine nucleotide catabolic process GO:0033121 2 0.081
cell surface receptor signaling pathway GO:0007166 325 0.081
signal transduction GO:0007165 455 0.081
Mouse
positive regulation of cell differentiation GO:0045597 30 0.080
regulation of cellular amino acid metabolic process GO:0006521 0 0.080
action potential GO:0001508 19 0.076
morphogenesis of embryonic epithelium GO:0016331 30 0.075
forebrain cell migration GO:0021885 1 0.074
head development GO:0060322 303 0.071
convergent extension GO:0060026 118 0.071
regulation of neurogenesis GO:0050767 87 0.070
Mouse
glial cell differentiation GO:0010001 42 0.069
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.067
larval development GO:0002164 2 0.065
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.065
eye morphogenesis GO:0048592 144 0.064
regulation of response to stimulus GO:0048583 269 0.062
organelle localization GO:0051640 49 0.061
enzyme linked receptor protein signaling pathway GO:0007167 106 0.061
regulation of cell development GO:0060284 100 0.061
Mouse
sensory organ morphogenesis GO:0090596 200 0.060
gtp catabolic process GO:0006184 2 0.060
determination of heart left right asymmetry GO:0061371 117 0.060
positive regulation of cell communication GO:0010647 56 0.059
central nervous system myelination GO:0022010 2 0.057
convergent extension involved in organogenesis GO:0060029 10 0.057
developmental growth involved in morphogenesis GO:0060560 86 0.057
regulation of developmental process GO:0050793 247 0.056
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.055
liver development GO:0001889 96 0.054
positive regulation of cellular catabolic process GO:0031331 3 0.053
regulation of metabolic process GO:0019222 359 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
Mouse
erk1 and erk2 cascade GO:0070371 4 0.050
cell fate specification GO:0001708 68 0.050
cell substrate adhesion GO:0031589 4 0.049
ectodermal placode development GO:0071696 37 0.048
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.048
embryonic organ morphogenesis GO:0048562 274 0.047
mesenchymal cell development GO:0014031 78 0.047
retina development in camera type eye GO:0060041 146 0.047
mesenchyme development GO:0060485 127 0.046
single organism metabolic process GO:0044710 217 0.046
negative regulation of cellular catabolic process GO:0031330 3 0.045
cell proliferation in hindbrain GO:0021534 4 0.045
cognition GO:0050890 1 0.045
regulation of glial cell differentiation GO:0045685 4 0.045
Mouse
positive regulation of response to stimulus GO:0048584 80 0.045
organic substance biosynthetic process GO:1901576 289 0.045
diencephalon development GO:0021536 58 0.044
skeletal system development GO:0001501 181 0.044
cell part morphogenesis GO:0032990 246 0.043
positive regulation of rac protein signal transduction GO:0035022 1 0.043
response to drug GO:0042493 3 0.043
neuromuscular process controlling balance GO:0050885 3 0.043
cardioblast migration GO:0003260 7 0.042
cell migration to the midline involved in heart development GO:0003318 12 0.042
carboxylic acid metabolic process GO:0019752 22 0.042
cell morphogenesis involved in differentiation GO:0000904 195 0.041
positive regulation of secretion by cell GO:1903532 1 0.041
amine metabolic process GO:0009308 2 0.041
cellular amino acid metabolic process GO:0006520 7 0.040
cell migration involved in heart formation GO:0060974 10 0.040
vasculogenesis GO:0001570 41 0.040
cellular component morphogenesis GO:0032989 336 0.040
blood vessel morphogenesis GO:0048514 216 0.040
tube morphogenesis GO:0035239 349 0.038
forebrain neuron fate commitment GO:0021877 1 0.038
axon ensheathment GO:0008366 18 0.038
cell migration involved in heart development GO:0060973 22 0.038
phagocytosis GO:0006909 3 0.037
vasculature development GO:0001944 278 0.037
brain morphogenesis GO:0048854 18 0.037
hindbrain development GO:0030902 91 0.036
cellular amine metabolic process GO:0044106 2 0.036
erythrocyte differentiation GO:0030218 54 0.035
cell morphogenesis GO:0000902 289 0.035
startle response GO:0001964 4 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.035
developmental cell growth GO:0048588 52 0.035
positive regulation of developmental process GO:0051094 50 0.034
regulation of axonogenesis GO:0050770 32 0.034
positive regulation of transport GO:0051050 2 0.034
single organism transport GO:0044765 206 0.034
endocrine process GO:0050886 2 0.034
positive regulation of secretion GO:0051047 1 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
positive regulation of metabolic process GO:0009893 108 0.033
mesenchymal cell differentiation GO:0048762 87 0.033
axon development GO:0061564 166 0.033
Zebrafish
mitotic cell cycle process GO:1903047 48 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.032
stem cell proliferation GO:0072089 4 0.032
axon extension GO:0048675 45 0.032
outflow tract morphogenesis GO:0003151 1 0.032
ectodermal placode morphogenesis GO:0071697 32 0.031
Zebrafish
axon guidance GO:0007411 86 0.031
skeletal system morphogenesis GO:0048705 102 0.030
blood vessel development GO:0001568 246 0.030
cellular macromolecule metabolic process GO:0044260 391 0.030
neuronal action potential GO:0019228 18 0.029
multicellular organism growth GO:0035264 4 0.029
gliogenesis GO:0042063 45 0.029
Mouse
apoptotic process GO:0006915 116 0.029
response to ketone GO:1901654 1 0.029
cell proliferation in forebrain GO:0021846 3 0.029
regeneration GO:0031099 91 0.029
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.029
cellular ketone metabolic process GO:0042180 11 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
gene expression GO:0010467 252 0.028
cellular biosynthetic process GO:0044249 286 0.028
positive regulation of cellular process GO:0048522 201 0.027
embryonic skeletal system development GO:0048706 97 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
oxoacid metabolic process GO:0043436 31 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
nephron epithelium morphogenesis GO:0072088 1 0.027
maintenance of location GO:0051235 4 0.027
heart development GO:0007507 313 0.027
specification of axis polarity GO:0065001 4 0.027
axonogenesis GO:0007409 152 0.026
cytoskeleton organization GO:0007010 96 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
heart morphogenesis GO:0003007 156 0.026
neuron projection morphogenesis GO:0048812 161 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
specification of symmetry GO:0009799 204 0.026
commissural neuron axon guidance GO:0071679 3 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
regulation of signaling GO:0023051 235 0.025
cell fate commitment GO:0045165 99 0.025
locomotion GO:0040011 313 0.025
digestive tract development GO:0048565 265 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.025
positive regulation of cell substrate adhesion GO:0010811 1 0.025
neuron development GO:0048666 262 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
locomotor rhythm GO:0045475 3 0.025
g1 s transition of mitotic cell cycle GO:0000082 1 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
positive regulation of catabolic process GO:0009896 4 0.024
stem cell development GO:0048864 82 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
mitotic cell cycle embryonic GO:0045448 2 0.023
adult behavior GO:0030534 2 0.023
hemopoiesis GO:0030097 183 0.023
neural crest cell development GO:0014032 62 0.023
regulation of wnt signaling pathway GO:0030111 53 0.023
anterior posterior axis specification GO:0009948 20 0.023
peripheral nervous system development GO:0007422 55 0.023
posterior lateral line neuromast development GO:0048919 20 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
embryonic cranial skeleton morphogenesis GO:0048701 90 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
negative regulation of catabolic process GO:0009895 3 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
proximal distal pattern formation GO:0009954 1 0.022
negative regulation of nervous system development GO:0051961 22 0.022
Mouse
regulation of biosynthetic process GO:0009889 250 0.022
transport GO:0006810 220 0.022
positive regulation of ras protein signal transduction GO:0046579 1 0.022
regulation of cell migration GO:0030334 40 0.021
negative regulation of axon guidance GO:1902668 1 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
synaptic target recognition GO:0008039 1 0.021
homeostatic process GO:0042592 142 0.021
forebrain regionalization GO:0021871 4 0.021
regulation of cell death GO:0010941 103 0.020
phosphorus metabolic process GO:0006793 109 0.020
regulation of cell communication GO:0010646 232 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
canonical wnt signaling pathway GO:0060070 48 0.020
gtp metabolic process GO:0046039 4 0.020
ensheathment of neurons GO:0007272 18 0.020
regulation of rac protein signal transduction GO:0035020 1 0.020
peptide transport GO:0015833 1 0.020
neural crest cell differentiation GO:0014033 72 0.019
negative regulation of gliogenesis GO:0014014 1 0.019
Mouse
regulation of protein complex assembly GO:0043254 3 0.019
regulation of hormone secretion GO:0046883 2 0.019
embryonic heart tube development GO:0035050 133 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.019
cell matrix adhesion GO:0007160 4 0.019
regulation of gtpase activity GO:0043087 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
cell death GO:0008219 121 0.019
epithelial cell differentiation GO:0030855 116 0.019
negative regulation of developmental process GO:0051093 65 0.019
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
positive regulation of cell matrix adhesion GO:0001954 1 0.019
neuron projection extension GO:1990138 45 0.019
immune system process GO:0002376 241 0.018
negative regulation of wnt signaling pathway GO:0030178 30 0.018
oligodendrocyte development GO:0014003 7 0.018
cell migration GO:0016477 237 0.018
epidermal cell differentiation GO:0009913 36 0.018
positive regulation of signal transduction GO:0009967 56 0.018
trigeminal nerve development GO:0021559 3 0.018
regulation of cellular component movement GO:0051270 55 0.018
cytokinesis GO:0000910 3 0.018
regulation of circadian rhythm GO:0042752 4 0.018
gastrulation GO:0007369 208 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
establishment of localization GO:0051234 244 0.017
olfactory bulb development GO:0021772 4 0.017
lipid catabolic process GO:0016042 4 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.017
cellular component biogenesis GO:0044085 178 0.017
immune system development GO:0002520 191 0.017
response to axon injury GO:0048678 14 0.017
Zebrafish
mrna polyadenylation GO:0006378 2 0.017
calcium ion transport into cytosol GO:0060402 3 0.017
hormone secretion GO:0046879 2 0.017
pituitary gland development GO:0021983 16 0.017
segmentation GO:0035282 97 0.017
phagocytosis engulfment GO:0006911 1 0.017
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.016
wnt signaling pathway GO:0016055 80 0.016
regulation of cell projection organization GO:0031344 44 0.016
single organism organelle organization GO:1902589 199 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of catalytic activity GO:0050790 55 0.016
death GO:0016265 121 0.016
multicellular organismal signaling GO:0035637 22 0.016
ear morphogenesis GO:0042471 64 0.016
cellular protein modification process GO:0006464 100 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.016
programmed cell death GO:0012501 119 0.016
cell projection organization GO:0030030 284 0.016
Zebrafish Mouse
protein import GO:0017038 3 0.016
cell proliferation in midbrain GO:0033278 4 0.016
regulation of cell cycle GO:0051726 52 0.016
urogenital system development GO:0001655 97 0.016
regulation of gene expression GO:0010468 265 0.016
neural tube formation GO:0001841 16 0.016
regulation of jak stat cascade GO:0046425 3 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.015
organic acid metabolic process GO:0006082 31 0.015
transcription dna templated GO:0006351 181 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
purine nucleotide metabolic process GO:0006163 27 0.015
metencephalon development GO:0022037 27 0.015
lateral line system development GO:0048925 76 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
Mouse
gland development GO:0048732 143 0.015
localization of cell GO:0051674 244 0.015
dopaminergic neuron differentiation GO:0071542 14 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
axis specification GO:0009798 43 0.015
otic vesicle development GO:0071599 42 0.014
determination of left right symmetry GO:0007368 179 0.014
small molecule metabolic process GO:0044281 77 0.014
entrainment of circadian clock GO:0009649 2 0.014
cellular component movement GO:0006928 335 0.014
axon midline choice point recognition GO:0016199 4 0.014
sympathetic nervous system development GO:0048485 3 0.014
regulation of mechanoreceptor differentiation GO:0045631 1 0.014
neuron remodeling GO:0016322 1 0.014
regulation of transporter activity GO:0032409 2 0.014
tyrosine phosphorylation of stat protein GO:0007260 1 0.014
sensory system development GO:0048880 76 0.014
regulation of reproductive process GO:2000241 4 0.014
negative regulation of cell development GO:0010721 26 0.014
Mouse
regulation of signal transduction GO:0009966 225 0.014
establishment of localization in cell GO:0051649 77 0.014
regulation of nucleotide metabolic process GO:0006140 17 0.014
regulation of dendrite development GO:0050773 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
response to monosaccharide GO:0034284 3 0.013
cellular component assembly GO:0022607 170 0.013
telencephalon development GO:0021537 14 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
central nervous system neuron development GO:0021954 29 0.013
Mouse
development of primary female sexual characteristics GO:0046545 4 0.013
response to carbohydrate GO:0009743 3 0.013
gabaergic neuron differentiation GO:0097154 2 0.013
somatic stem cell maintenance GO:0035019 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
inner ear receptor cell fate commitment GO:0060120 4 0.013
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.013
epithelial tube formation GO:0072175 19 0.013
neuroblast proliferation GO:0007405 2 0.013
regulation of purine nucleotide metabolic process GO:1900542 17 0.012
nucleic acid metabolic process GO:0090304 244 0.012
eye photoreceptor cell differentiation GO:0001754 45 0.012
developmental growth GO:0048589 166 0.012
rna biosynthetic process GO:0032774 181 0.012
glucose homeostasis GO:0042593 1 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
atp catabolic process GO:0006200 4 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of cell cycle g2 m phase transition GO:1902749 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.012
regulation of cell motility GO:2000145 46 0.012
carbohydrate homeostasis GO:0033500 1 0.012
fertilization GO:0009566 3 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
mechanoreceptor differentiation GO:0042490 37 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
extracellular structure organization GO:0043062 27 0.012
regulation of primary metabolic process GO:0080090 311 0.012
protein targeting to nucleus GO:0044744 3 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
nuclear export GO:0051168 1 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
positive regulation of cell development GO:0010720 25 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
regulation of neuron differentiation GO:0045664 56 0.011
dendrite guidance GO:0070983 0 0.011
inner ear morphogenesis GO:0042472 63 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
response to chemical GO:0042221 320 0.011
positive regulation of signaling GO:0023056 56 0.011
negative regulation of cellular process GO:0048523 283 0.011
Mouse
dorsal ventral pattern formation GO:0009953 125 0.011
stem cell maintenance GO:0019827 4 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
response to unfolded protein GO:0006986 2 0.011
myeloid cell differentiation GO:0030099 86 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cell adhesion GO:0007155 40 0.011
transmission of nerve impulse GO:0019226 19 0.011
neuron projection guidance GO:0097485 86 0.010
kidney development GO:0001822 92 0.010
olfactory lobe development GO:0021988 4 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
nuclear import GO:0051170 3 0.010
muscle cell differentiation GO:0042692 139 0.010
organism emergence from protective structure GO:0071684 4 0.010
response to amino acid GO:0043200 2 0.010
pons development GO:0021548 11 0.010
cell projection assembly GO:0030031 64 0.010
heart looping GO:0001947 94 0.010
negative regulation of gene expression GO:0010629 65 0.010
positive regulation of nervous system development GO:0051962 25 0.010
otic vesicle formation GO:0030916 27 0.010
nephron morphogenesis GO:0072028 2 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.010
response to organic substance GO:0010033 153 0.010

lingo1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
amyloidosis DOID:9120 0 0.051
acquired metabolic disease DOID:0060158 0 0.051
disease of metabolism DOID:0014667 0 0.051