Danio rerio

0 known processes

litaf

lipopolysaccharide-induced TNF factor

(Aliases: id:ibd5018,wu:fb12g04,zgc:91882)

litaf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism transport GO:0044765 206 0.162
Mouse
regulation of metabolic process GO:0019222 359 0.161
regulation of multicellular organismal process GO:0051239 277 0.129
Mouse
cell projection organization GO:0030030 284 0.121
cellular macromolecule metabolic process GO:0044260 391 0.116
positive regulation of biological process GO:0048518 253 0.116
Human
regulation of macromolecule metabolic process GO:0060255 317 0.111
nuclear transport GO:0051169 4 0.098
Mouse
establishment of protein localization to organelle GO:0072594 4 0.096
Mouse
signal transduction GO:0007165 455 0.096
Human Mouse
establishment of localization GO:0051234 244 0.093
Mouse
macromolecule biosynthetic process GO:0009059 227 0.087
i kappab kinase nf kappab signaling GO:0007249 4 0.087
Human Mouse
regulation of cell communication GO:0010646 232 0.080
Human Mouse
regulation of signal transduction GO:0009966 225 0.074
Human Mouse
regulation of signaling GO:0023051 235 0.073
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.073
Human Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.072
Mouse
protein targeting to nucleus GO:0044744 3 0.066
Mouse
positive regulation of cellular process GO:0048522 201 0.064
Human
transport GO:0006810 220 0.064
Mouse
regulation of cellular metabolic process GO:0031323 320 0.063
positive regulation of signaling GO:0023056 56 0.062
Human
maintenance of location GO:0051235 4 0.062
negative regulation of cellular process GO:0048523 283 0.058
Mouse
single organism metabolic process GO:0044710 217 0.057
lipid storage GO:0019915 1 0.052
response to stress GO:0006950 263 0.051
nuclear import GO:0051170 3 0.051
Mouse
organic substance transport GO:0071702 58 0.051
Mouse
negative regulation of protein localization to nucleus GO:1900181 2 0.050
Mouse
regulation of gene expression GO:0010468 265 0.050
immune system process GO:0002376 241 0.050
regulation of localization GO:0032879 104 0.049
Mouse
response to chemical GO:0042221 320 0.049
Mouse
positive regulation of signal transduction GO:0009967 56 0.048
Human
intracellular signal transduction GO:0035556 85 0.046
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.045
cell surface receptor signaling pathway GO:0007166 325 0.044
regulation of multicellular organismal development GO:2000026 223 0.043
regulation of response to stimulus GO:0048583 269 0.043
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.041
positive regulation of response to stimulus GO:0048584 80 0.041
Human
regulation of transmembrane transporter activity GO:0022898 2 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
cellular response to starvation GO:0009267 1 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
cellular response to chemical stimulus GO:0070887 157 0.039
Mouse
cell proliferation GO:0008283 80 0.039
reactive nitrogen species metabolic process GO:2001057 0 0.038
positive regulation of transport GO:0051050 2 0.038
aging GO:0007568 2 0.038
gtp metabolic process GO:0046039 4 0.038
regulation of cytokine production GO:0001817 3 0.037
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.037
protein localization to nucleus GO:0034504 3 0.037
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.037
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.037
regulation of nucleotide catabolic process GO:0030811 2 0.036
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.035
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.034
organelle organization GO:0006996 227 0.034
positive regulation of gene expression GO:0010628 71 0.034
response to wounding GO:0009611 116 0.034
protein import into nucleus GO:0006606 3 0.033
Mouse
regulation of reproductive process GO:2000241 4 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.033
wound healing GO:0042060 90 0.032
organic substance biosynthetic process GO:1901576 289 0.032
positive regulation of metabolic process GO:0009893 108 0.032
heterocycle metabolic process GO:0046483 290 0.032
regulation of neurotransmitter secretion GO:0046928 1 0.032
endosome to lysosome transport GO:0008333 1 0.031
response to carbohydrate GO:0009743 3 0.031
negative regulation of protein import into nucleus GO:0042308 2 0.031
Mouse
larval development GO:0002164 2 0.031
neuron differentiation GO:0030182 353 0.031
positive regulation of gtpase activity GO:0043547 1 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.030
b cell differentiation GO:0030183 1 0.030
positive regulation of biosynthetic process GO:0009891 68 0.030
positive regulation of cell killing GO:0031343 2 0.030
lytic vacuole organization GO:0080171 1 0.030
biosynthetic process GO:0009058 294 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
regulation of anatomical structure morphogenesis GO:0022603 130 0.030
leukocyte mediated cytotoxicity GO:0001909 1 0.029
regulation of primary metabolic process GO:0080090 311 0.029
calcium ion transport into cytosol GO:0060402 3 0.029
chordate embryonic development GO:0043009 271 0.028
negative regulation of protein transport GO:0051224 3 0.027
Mouse
cell morphogenesis GO:0000902 289 0.027
leukocyte proliferation GO:0070661 1 0.027
cell part morphogenesis GO:0032990 246 0.027
organic acid metabolic process GO:0006082 31 0.027
axon development GO:0061564 166 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.027
phagocytosis GO:0006909 3 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
Mouse
neuron development GO:0048666 262 0.026
positive regulation of transcription dna templated GO:0045893 57 0.026
regulation of cytoplasmic transport GO:1903649 4 0.025
Mouse
nucleocytoplasmic transport GO:0006913 4 0.025
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.025
cellular component biogenesis GO:0044085 178 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
Mouse
single organism nuclear import GO:1902593 3 0.025
Mouse
positive regulation of cell communication GO:0010647 56 0.025
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
positive regulation of secretion GO:0051047 1 0.024
cellular component morphogenesis GO:0032989 336 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of embryonic development GO:0045995 47 0.024
nucleic acid templated transcription GO:0097659 181 0.024
generation of neurons GO:0048699 385 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of transcription dna templated GO:0006355 213 0.023
immune response GO:0006955 28 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
negative regulation of intracellular protein transport GO:0090317 3 0.023
Mouse
meiotic nuclear division GO:0007126 4 0.023
developmental growth GO:0048589 166 0.023
positive regulation of neuron death GO:1901216 1 0.023
transcription dna templated GO:0006351 181 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.023
exocytosis GO:0006887 1 0.022
multicellular organism growth GO:0035264 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
rna localization GO:0006403 4 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
nucleic acid metabolic process GO:0090304 244 0.022
b cell activation GO:0042113 2 0.022
negative regulation of multicellular organismal process GO:0051241 69 0.022
positive regulation of immune effector process GO:0002699 3 0.022
regulation of rna metabolic process GO:0051252 224 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.021
positive regulation of epithelial cell differentiation GO:0030858 2 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
Mouse
homeostatic process GO:0042592 142 0.021
locomotion GO:0040011 313 0.021
negative regulation of biological process GO:0048519 304 0.021
Mouse
regulation of gtp catabolic process GO:0033124 2 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
mononuclear cell proliferation GO:0032943 1 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.021
regulation of response to cytokine stimulus GO:0060759 3 0.020
cellular protein catabolic process GO:0044257 4 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
actin filament based movement GO:0030048 1 0.020
negative regulation of signaling GO:0023057 96 0.020
Mouse
toll like receptor signaling pathway GO:0002224 4 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.020
Human
nitrogen compound metabolic process GO:0006807 319 0.020
membrane invagination GO:0010324 1 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
neuron projection development GO:0031175 180 0.020
lymphocyte proliferation GO:0046651 1 0.019
response to oxygen containing compound GO:1901700 55 0.019
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of cell maturation GO:1903429 1 0.019
positive regulation of rna biosynthetic process GO:1902680 57 0.019
positive regulation of secretion by cell GO:1903532 1 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
Mouse
response to organic substance GO:0010033 153 0.018
Mouse
cellular biosynthetic process GO:0044249 286 0.018
hemopoiesis GO:0030097 183 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of metal ion transport GO:0010959 4 0.018
positive regulation of multicellular organismal process GO:0051240 52 0.018
intestinal absorption GO:0050892 2 0.018
peptide transport GO:0015833 1 0.018
Mouse
superoxide metabolic process GO:0006801 2 0.018
b cell mediated immunity GO:0019724 3 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
homeostasis of number of cells within a tissue GO:0048873 4 0.017
synaptic transmission cholinergic GO:0007271 4 0.017
response to hexose GO:0009746 3 0.017
mitotic cytokinesis GO:0000281 3 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
regulation of apoptotic process GO:0042981 98 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
cytoplasm organization GO:0007028 4 0.016
cell death GO:0008219 121 0.016
response to monosaccharide GO:0034284 3 0.016
gtp catabolic process GO:0006184 2 0.016
gene expression GO:0010467 252 0.016
regulation of cell development GO:0060284 100 0.016
regulation of programmed cell death GO:0043067 101 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of sodium ion transport GO:0002028 2 0.016
cellular response to nutrient levels GO:0031669 2 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.015
single organism membrane fusion GO:0044801 2 0.015
positive regulation of rna metabolic process GO:0051254 59 0.015
axonogenesis GO:0007409 152 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
stem cell proliferation GO:0072089 4 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cell projection morphogenesis GO:0048858 244 0.015
positive regulation of immune response GO:0050778 11 0.015
death GO:0016265 121 0.015
regulation of intracellular ph GO:0051453 1 0.015
cytosolic calcium ion transport GO:0060401 3 0.015
cellular localization GO:0051641 97 0.015
Mouse
release of sequestered calcium ion into cytosol GO:0051209 3 0.015
cellular response to external stimulus GO:0071496 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.015
response to drug GO:0042493 3 0.015
positive regulation of cytokine production GO:0001819 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
phagosome maturation GO:0090382 1 0.015
cell killing GO:0001906 2 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of biological quality GO:0065008 263 0.015
ion transport GO:0006811 114 0.014
regulation of protein transport GO:0051223 3 0.014
Mouse
smooth muscle contraction GO:0006939 2 0.014
septum transversum development GO:0003343 4 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
positive regulation of multi organism process GO:0043902 3 0.014
system process GO:0003008 185 0.014
response to nutrient GO:0007584 3 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of response to oxidative stress GO:1902882 2 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
response to glucose GO:0009749 3 0.014
cellular protein metabolic process GO:0044267 129 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
carbohydrate homeostasis GO:0033500 1 0.014
establishment of localization in cell GO:0051649 77 0.014
Mouse
lipid digestion GO:0044241 3 0.014
regulation of protein targeting GO:1903533 2 0.014
Mouse
membrane fusion GO:0061025 2 0.014
regulation of muscle contraction GO:0006937 3 0.013
neutrophil mediated immunity GO:0002446 1 0.013
response to external biotic stimulus GO:0043207 97 0.013
Mouse
sensory perception of chemical stimulus GO:0007606 3 0.013
regulation of locomotion GO:0040012 55 0.013
autophagy GO:0006914 4 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
sequestering of calcium ion GO:0051208 3 0.013
neuroblast proliferation GO:0007405 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
cytoskeleton organization GO:0007010 96 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
innate immune response GO:0045087 13 0.013
regulation of binding GO:0051098 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of oligodendrocyte differentiation GO:0048713 1 0.013
single organism localization GO:1902578 225 0.013
Mouse
regulation of cell differentiation GO:0045595 142 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
endosomal transport GO:0016197 2 0.013
immune effector process GO:0002252 23 0.013
rna metabolic process GO:0016070 219 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of lipid transport GO:0032368 4 0.013
regulation of cytokine biosynthetic process GO:0042035 1 0.013
hormone transport GO:0009914 2 0.012
cell growth GO:0016049 57 0.012
positive regulation of reproductive process GO:2000243 2 0.012
cellular response to organic substance GO:0071310 105 0.012
Mouse
receptor recycling GO:0001881 4 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
Mouse
positive regulation of gliogenesis GO:0014015 2 0.012
plasma membrane repair GO:0001778 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
angiogenesis GO:0001525 158 0.012
protein metabolic process GO:0019538 183 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of oocyte development GO:0060281 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
lipid homeostasis GO:0055088 3 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
cardiac conduction GO:0061337 3 0.012
regulation of protein catabolic process GO:0042176 1 0.011
response to external stimulus GO:0009605 264 0.011
Mouse
regulation of ph GO:0006885 3 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
positive regulation of catabolic process GO:0009896 4 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of gtpase activity GO:0043087 2 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
regulation of transporter activity GO:0032409 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
neurotransmitter transport GO:0006836 2 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
synaptic vesicle localization GO:0097479 1 0.011
response to amino acid GO:0043200 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
protein localization to plasma membrane GO:0072659 1 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
cell cell recognition GO:0009988 1 0.011
hormone secretion GO:0046879 2 0.011
anterior posterior pattern specification GO:0009952 152 0.011
cellular amide metabolic process GO:0043603 4 0.011
protein dephosphorylation GO:0006470 3 0.011
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.011
Mouse
regulation of calcium ion transport GO:0051924 2 0.010
apoptotic process GO:0006915 116 0.010
rna biosynthetic process GO:0032774 181 0.010
lipid catabolic process GO:0016042 4 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
single organism cellular localization GO:1902580 46 0.010
Mouse
reactive oxygen species metabolic process GO:0072593 6 0.010
actin mediated cell contraction GO:0070252 1 0.010
regulation of glycoprotein biosynthetic process GO:0010559 3 0.010
organism emergence from protective structure GO:0071684 4 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
growth GO:0040007 174 0.010
cellular catabolic process GO:0044248 27 0.010

litaf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.198
Human
immune system disease DOID:2914 0 0.047
primary immunodeficiency disease DOID:612 0 0.018
inherited metabolic disorder DOID:655 0 0.017
disease of metabolism DOID:0014667 0 0.017