Danio rerio

20 known processes

lman1

lectin, mannose-binding, 1

(Aliases: wu:fc54c09,wu:fi36e01)

lman1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lipid storage GO:0019915 1 0.246
response to chemical GO:0042221 320 0.154
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
response to organic substance GO:0010033 153 0.098
maintenance of location GO:0051235 4 0.093
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.092
regulation of organ growth GO:0046620 3 0.075
regulation of metabolic process GO:0019222 359 0.074
protein targeting to membrane GO:0006612 1 0.074
gtp metabolic process GO:0046039 4 0.072
negative regulation of biological process GO:0048519 304 0.070
proteasomal protein catabolic process GO:0010498 2 0.067
cellular response to endogenous stimulus GO:0071495 68 0.067
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.066
cellular biosynthetic process GO:0044249 286 0.065
cellular response to topologically incorrect protein GO:0035967 2 0.065
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.062
central nervous system development GO:0007417 387 0.060
negative regulation of cellular catabolic process GO:0031330 3 0.059
multicellular organism growth GO:0035264 4 0.059
larval development GO:0002164 2 0.055
negative regulation of catabolic process GO:0009895 3 0.053
protein n linked glycosylation GO:0006487 1 0.052
signal transduction GO:0007165 455 0.052
cellular response to organic substance GO:0071310 105 0.051
regulation of multicellular organism growth GO:0040014 4 0.050
gene expression GO:0010467 252 0.049
regulation of protein ubiquitination GO:0031396 3 0.046
chordate embryonic development GO:0043009 271 0.045
modification dependent protein catabolic process GO:0019941 3 0.044
cellular protein catabolic process GO:0044257 4 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.043
specification of symmetry GO:0009799 204 0.043
regulation of biological quality GO:0065008 263 0.042
ubiquitin dependent protein catabolic process GO:0006511 3 0.041
embryonic organ development GO:0048568 381 0.040
brain development GO:0007420 293 0.040
cellular protein metabolic process GO:0044267 129 0.039
positive regulation of gene expression GO:0010628 71 0.037
modification dependent macromolecule catabolic process GO:0043632 3 0.037
heart looping GO:0001947 94 0.036
response to endogenous stimulus GO:0009719 83 0.036
single organism localization GO:1902578 225 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
embryonic heart tube morphogenesis GO:0003143 108 0.034
positive regulation of biological process GO:0048518 253 0.034
carbohydrate metabolic process GO:0005975 12 0.034
endoplasmic reticulum unfolded protein response GO:0030968 2 0.033
adult behavior GO:0030534 2 0.033
determination of left right symmetry GO:0007368 179 0.033
regulation of multicellular organismal process GO:0051239 277 0.032
amine metabolic process GO:0009308 2 0.032
organic cyclic compound metabolic process GO:1901360 301 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
cell cycle GO:0007049 93 0.031
regulation of primary metabolic process GO:0080090 311 0.030
biosynthetic process GO:0009058 294 0.029
response to unfolded protein GO:0006986 2 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
positive regulation of transcription dna templated GO:0045893 57 0.028
protein import GO:0017038 3 0.028
single organism transport GO:0044765 206 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
negative regulation of purine nucleotide metabolic process GO:1900543 7 0.026
positive regulation of biosynthetic process GO:0009891 68 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.026
response to topologically incorrect protein GO:0035966 2 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.026
response to external biotic stimulus GO:0043207 97 0.026
regulation of biosynthetic process GO:0009889 250 0.026
organic substance biosynthetic process GO:1901576 289 0.026
response to external stimulus GO:0009605 264 0.025
negative regulation of metabolic process GO:0009892 86 0.025
programmed cell death GO:0012501 119 0.025
hormone transport GO:0009914 2 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
er nucleus signaling pathway GO:0006984 2 0.024
regulation of gtpase activity GO:0043087 2 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
locomotion GO:0040011 313 0.024
regulation of signal transduction GO:0009966 225 0.023
growth GO:0040007 174 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
golgi vesicle transport GO:0048193 3 0.023
regulation of developmental process GO:0050793 247 0.023
cell surface receptor signaling pathway GO:0007166 325 0.022
head development GO:0060322 303 0.022
regulation of response to stimulus GO:0048583 269 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
cell death GO:0008219 121 0.022
positive regulation of cellular biosynthetic process GO:0031328 68 0.022
nitrogen compound metabolic process GO:0006807 319 0.021
regulation of cell communication GO:0010646 232 0.021
cellular localization GO:0051641 97 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of gene expression GO:0010468 265 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
peptide transport GO:0015833 1 0.020
erythrocyte differentiation GO:0030218 54 0.020
aging GO:0007568 2 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
establishment of localization GO:0051234 244 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
positive regulation of transport GO:0051050 2 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
transcription dna templated GO:0006351 181 0.019
regulation of rna metabolic process GO:0051252 224 0.019
regulation of cell activation GO:0050865 1 0.019
regulation of transcription dna templated GO:0006355 213 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
renal absorption GO:0070293 1 0.018
response to stress GO:0006950 263 0.018
negative regulation of cellular process GO:0048523 283 0.018
protein glycosylation GO:0006486 9 0.018
response to biotic stimulus GO:0009607 97 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
single organism metabolic process GO:0044710 217 0.018
glycosylation GO:0070085 11 0.017
heart development GO:0007507 313 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
regulation of signaling GO:0023051 235 0.017
cellular response to unfolded protein GO:0034620 2 0.017
protein metabolic process GO:0019538 183 0.017
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of protein binding GO:0043393 3 0.016
response to vitamin b3 GO:0033552 2 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
embryonic heart tube development GO:0035050 133 0.016
positive regulation of translation GO:0045727 1 0.015
cellular response to organic cyclic compound GO:0071407 38 0.015
system process GO:0003008 185 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of hormone secretion GO:0046883 2 0.015
positive regulation of striated muscle cell differentiation GO:0051155 1 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.014
response to endoplasmic reticulum stress GO:0034976 6 0.014
apoptotic process GO:0006915 116 0.014
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
generation of neurons GO:0048699 385 0.014
immune system development GO:0002520 191 0.014
single organism carbohydrate metabolic process GO:0044723 12 0.014
macromolecule modification GO:0043412 111 0.014
macromolecule localization GO:0033036 54 0.014
rna biosynthetic process GO:0032774 181 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
exocytosis GO:0006887 1 0.013
gtp catabolic process GO:0006184 2 0.013
single organism organelle organization GO:1902589 199 0.013
regulation of blood vessel size GO:0050880 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of growth GO:0040008 42 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
organelle organization GO:0006996 227 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
regulation of reproductive process GO:2000241 4 0.013
b cell mediated immunity GO:0019724 3 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
cellular amine metabolic process GO:0044106 2 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
cell migration GO:0016477 237 0.012
cellular lipid catabolic process GO:0044242 3 0.012
germ line stem cell division GO:0042078 1 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
tube morphogenesis GO:0035239 349 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
glycerophospholipid biosynthetic process GO:0046474 1 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
positive regulation of catabolic process GO:0009896 4 0.011
establishment of localization in cell GO:0051649 77 0.011
cell growth GO:0016049 57 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
cellular response to starvation GO:0009267 1 0.011
cell motility GO:0048870 244 0.011
regulation of tube size GO:0035150 2 0.011
purine ribonucleotide metabolic process GO:0009150 27 0.011
positive regulation of secretion GO:0051047 1 0.011
primary neural tube formation GO:0014020 1 0.011
positive regulation of cell cycle GO:0045787 3 0.011
protein modification process GO:0036211 100 0.011
autophagy GO:0006914 4 0.011
transport GO:0006810 220 0.010
negative regulation of developmental process GO:0051093 65 0.010
cellular response to stress GO:0033554 62 0.010
positive regulation of multi organism process GO:0043902 3 0.010
response to other organism GO:0051707 97 0.010

lman1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.022
connective tissue disease DOID:65 0 0.021
musculoskeletal system disease DOID:17 0 0.021
bone disease DOID:0080001 0 0.013
bone development disease DOID:0080006 0 0.013
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010