Danio rerio

0 known processes

lonp2

lon peptidase 2, peroxisomal

(Aliases: zgc:92557,wu:fc51e03)

lonp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 3 0.160
Human
negative regulation of protein complex assembly GO:0031333 1 0.158
lipid catabolic process GO:0016042 4 0.135
Human
regulation of protein complex assembly GO:0043254 3 0.100
cellular protein catabolic process GO:0044257 4 0.083
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.075
response to topologically incorrect protein GO:0035966 2 0.072
fatty acid catabolic process GO:0009062 1 0.066
Human
aging GO:0007568 2 0.063
ubiquitin dependent protein catabolic process GO:0006511 3 0.057
modification dependent macromolecule catabolic process GO:0043632 3 0.053
organic acid metabolic process GO:0006082 31 0.047
Human
organic acid catabolic process GO:0016054 3 0.045
Human
cell morphogenesis GO:0000902 289 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.044
modification dependent protein catabolic process GO:0019941 3 0.043
proteasomal protein catabolic process GO:0010498 2 0.043
cell projection organization GO:0030030 284 0.042
organelle organization GO:0006996 227 0.042
Human
lipid storage GO:0019915 1 0.042
carboxylic acid metabolic process GO:0019752 22 0.042
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.041
regulation of binding GO:0051098 3 0.039
negative regulation of biological process GO:0048519 304 0.039
centrosome organization GO:0051297 1 0.037
response to unfolded protein GO:0006986 2 0.037
sensory perception of chemical stimulus GO:0007606 3 0.036
regulation of stem cell proliferation GO:0072091 2 0.036
regulation of synapse organization GO:0050807 3 0.036
oxoacid metabolic process GO:0043436 31 0.035
Human
regulation of synapse assembly GO:0051963 3 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.034
maintenance of location GO:0051235 4 0.033
neuron differentiation GO:0030182 353 0.033
lipid oxidation GO:0034440 1 0.033
Human
response to organic substance GO:0010033 153 0.032
response to chemical GO:0042221 320 0.032
regulation of biological quality GO:0065008 263 0.032
cellular response to external stimulus GO:0071496 2 0.032
protein polyubiquitination GO:0000209 4 0.032
secondary metabolic process GO:0019748 3 0.032
generation of neurons GO:0048699 385 0.031
amine metabolic process GO:0009308 2 0.031
sensory perception of smell GO:0007608 2 0.031
cellular lipid catabolic process GO:0044242 3 0.031
Human
lateral inhibition GO:0046331 1 0.030
response to transition metal nanoparticle GO:1990267 28 0.029
microtubule organizing center organization GO:0031023 1 0.029
positive regulation of transport GO:0051050 2 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.029
adult behavior GO:0030534 2 0.028
er nucleus signaling pathway GO:0006984 2 0.027
protein import GO:0017038 3 0.027
multicellular organism growth GO:0035264 4 0.027
cell projection morphogenesis GO:0048858 244 0.027
cognition GO:0050890 1 0.026
alcohol biosynthetic process GO:0046165 2 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
establishment of localization GO:0051234 244 0.026
Human
regulation of oocyte development GO:0060281 3 0.026
negative regulation of protein kinase activity GO:0006469 4 0.025
cellular lipid metabolic process GO:0044255 36 0.025
Human
fatty acid oxidation GO:0019395 1 0.025
Human
toxin metabolic process GO:0009404 1 0.025
monocarboxylic acid catabolic process GO:0072329 3 0.025
Human
negative regulation of protein phosphorylation GO:0001933 4 0.025
synaptic vesicle transport GO:0048489 1 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
protein metabolic process GO:0019538 183 0.024
Human
embryonic limb morphogenesis GO:0030326 2 0.023
cellular ketone metabolic process GO:0042180 11 0.023
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
phagocytosis GO:0006909 3 0.023
positive regulation of blood circulation GO:1903524 2 0.022
regulation of response to extracellular stimulus GO:0032104 1 0.022
positive regulation of catabolic process GO:0009896 4 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cellular component biogenesis GO:0044085 178 0.022
cellular response to topologically incorrect protein GO:0035967 2 0.022
regulation of blood vessel size GO:0050880 2 0.021
neuron projection morphogenesis GO:0048812 161 0.021
stem cell proliferation GO:0072089 4 0.021
nucleic acid metabolic process GO:0090304 244 0.021
negative regulation of kinase activity GO:0033673 4 0.021
negative regulation of cellular catabolic process GO:0031330 3 0.021
synaptic vesicle localization GO:0097479 1 0.021
positive regulation of cell cycle GO:0045787 3 0.021
cellular component morphogenesis GO:0032989 336 0.021
stem cell maintenance GO:0019827 4 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
response to alkaloid GO:0043279 2 0.021
regulation of metal ion transport GO:0010959 4 0.021
centrosome cycle GO:0007098 1 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
neurotransmitter transport GO:0006836 2 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
Human
post embryonic organ development GO:0048569 4 0.020
cell part morphogenesis GO:0032990 246 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
vasculature development GO:0001944 278 0.019
cellular response to starvation GO:0009267 1 0.019
regulation of receptor activity GO:0010469 2 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
regulation of organ growth GO:0046620 3 0.019
transport GO:0006810 220 0.019
Human
regulation of cytokine production GO:0001817 3 0.018
cell substrate adhesion GO:0031589 4 0.018
regulation of dendrite development GO:0050773 3 0.018
golgi vesicle transport GO:0048193 3 0.018
protein homooligomerization GO:0051260 3 0.018
regulation of reproductive process GO:2000241 4 0.018
pole plasm assembly GO:0007315 4 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
protein modification process GO:0036211 100 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
protein polymerization GO:0051258 4 0.018
cytoplasm organization GO:0007028 4 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
regulation of protein binding GO:0043393 3 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
cellular response to unfolded protein GO:0034620 2 0.017
centrosome duplication GO:0051298 1 0.017
regulation of gene expression GO:0010468 265 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
regulation of intracellular ph GO:0051453 1 0.017
response to stress GO:0006950 263 0.017
regulation of establishment of protein localization GO:0070201 4 0.016
rna localization GO:0006403 4 0.016
cellular component maintenance GO:0043954 3 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
larval development GO:0002164 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
regulation of developmental process GO:0050793 247 0.016
small molecule metabolic process GO:0044281 77 0.016
Human
embryonic organ development GO:0048568 381 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
primary neural tube formation GO:0014020 1 0.016
immune system process GO:0002376 241 0.016
axonogenesis GO:0007409 152 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
protein targeting to membrane GO:0006612 1 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
protein acetylation GO:0006473 2 0.015
regulation of axonogenesis GO:0050770 32 0.015
adherens junction organization GO:0034332 4 0.015
organelle fusion GO:0048284 3 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
rna biosynthetic process GO:0032774 181 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
macroautophagy GO:0016236 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
cellular response to radiation GO:0071478 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
dna templated transcription elongation GO:0006354 3 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
transmembrane transport GO:0055085 120 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
cellular component movement GO:0006928 335 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
single organism metabolic process GO:0044710 217 0.014
Human
regulation of protein transport GO:0051223 3 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
cellular component assembly GO:0022607 170 0.014
rna metabolic process GO:0016070 219 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
intracellular mrna localization GO:0008298 1 0.014
sensory organ development GO:0007423 393 0.014
camera type eye development GO:0043010 222 0.014
cellular response to nutrient levels GO:0031669 2 0.014
eye development GO:0001654 277 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
developmental growth GO:0048589 166 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
response to corticosteroid GO:0031960 1 0.014
heterocycle metabolic process GO:0046483 290 0.014
regulation of cell development GO:0060284 100 0.014
negative regulation of cellular process GO:0048523 283 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
neuroblast proliferation GO:0007405 2 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
tube morphogenesis GO:0035239 349 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
negative regulation of cellular component organization GO:0051129 16 0.013
tube closure GO:0060606 1 0.013
autophagy GO:0006914 4 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of nervous system development GO:0051960 90 0.013
fatty acid beta oxidation GO:0006635 1 0.013
Human
organic cyclic compound metabolic process GO:1901360 301 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
growth GO:0040007 174 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
ion transport GO:0006811 114 0.013
post embryonic morphogenesis GO:0009886 4 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
cellular protein metabolic process GO:0044267 129 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.013
skeletal system development GO:0001501 181 0.013
regulation of transporter activity GO:0032409 2 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
negative regulation of catabolic process GO:0009895 3 0.013
central nervous system development GO:0007417 387 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
epithelial cell differentiation GO:0030855 116 0.013
positive regulation of secretion GO:0051047 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
dorsal ventral neural tube patterning GO:0021904 1 0.013
behavior GO:0007610 74 0.013
chordate embryonic development GO:0043009 271 0.013
system process GO:0003008 185 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regionalization GO:0003002 274 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
gtp metabolic process GO:0046039 4 0.012
lipid metabolic process GO:0006629 52 0.012
Human
signal transduction GO:0007165 455 0.012
compound eye development GO:0048749 2 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
digestive system development GO:0055123 289 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
meiotic cell cycle process GO:1903046 3 0.012
germ line stem cell maintenance GO:0030718 2 0.012
nuclear migration GO:0007097 3 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
sensory organ morphogenesis GO:0090596 200 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
single organism transport GO:0044765 206 0.012
Human
digestive tract development GO:0048565 265 0.012
thermosensory behavior GO:0040040 1 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
somatic muscle development GO:0007525 4 0.012
regulation of cell maturation GO:1903429 1 0.012
neuron development GO:0048666 262 0.012
monocarboxylic acid metabolic process GO:0032787 17 0.012
Human
peptidyl lysine acetylation GO:0018394 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
response to uv GO:0009411 3 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
positive regulation of biological process GO:0048518 253 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
epidermal cell fate specification GO:0009957 4 0.012
cytokinesis GO:0000910 3 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
muscle structure development GO:0061061 196 0.011
regulation of rna metabolic process GO:0051252 224 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
cell growth GO:0016049 57 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
response to nutrient GO:0007584 3 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
cellular response to stress GO:0033554 62 0.011
negative regulation of cytokine production GO:0001818 1 0.011
receptor recycling GO:0001881 4 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Human
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
regulation of cell shape GO:0008360 1 0.011
monoamine transport GO:0015844 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
small molecule catabolic process GO:0044282 3 0.011
Human
regulation of transcription dna templated GO:0006355 213 0.011
cellular component disassembly GO:0022411 1 0.011
cellular respiration GO:0045333 3 0.011
response to glucocorticoid GO:0051384 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
single organism organelle organization GO:1902589 199 0.011
Human
cell junction maintenance GO:0034331 2 0.011
membrane fusion GO:0061025 2 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
eye morphogenesis GO:0048592 144 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of autophagy GO:0010506 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
meiotic nuclear division GO:0007126 4 0.011
regulation of cellular component organization GO:0051128 86 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
neuron projection development GO:0031175 180 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
adherens junction maintenance GO:0034334 2 0.011
stem cell division GO:0017145 1 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
response to vitamin GO:0033273 3 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
blood vessel development GO:0001568 246 0.010
aflatoxin metabolic process GO:0046222 1 0.010
nucleic acid transport GO:0050657 2 0.010
synaptic vesicle recycling GO:0036465 1 0.010
ion transmembrane transport GO:0034220 91 0.010
lymph vessel morphogenesis GO:0036303 25 0.010
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
hemopoiesis GO:0030097 183 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
response to abiotic stimulus GO:0009628 122 0.010
hormone secretion GO:0046879 2 0.010
brain development GO:0007420 293 0.010
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.010
homeostatic process GO:0042592 142 0.010
single organism membrane fusion GO:0044801 2 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of neurogenesis GO:0050767 87 0.010
regulation of sodium ion transport GO:0002028 2 0.010
keratinocyte differentiation GO:0030216 0 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
cellular amide metabolic process GO:0043603 4 0.010

lonp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.087
nervous system disease DOID:863 0 0.048
cardiovascular system disease DOID:1287 0 0.032
disease of metabolism DOID:0014667 0 0.025
musculoskeletal system disease DOID:17 0 0.022
inherited metabolic disorder DOID:655 0 0.018
muscular disease DOID:0080000 0 0.017
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
cancer DOID:162 0 0.016
muscle tissue disease DOID:66 0 0.015
myopathy DOID:423 0 0.015
immune system disease DOID:2914 0 0.014
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
lysosomal storage disease DOID:3211 0 0.013
central nervous system disease DOID:331 0 0.013
brain disease DOID:936 0 0.013
hematopoietic system disease DOID:74 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.011