Danio rerio

40 known processes

lrrc10

leucine rich repeat containing 10

lrrc10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.264
embryonic organ morphogenesis GO:0048562 274 0.217
muscle tissue development GO:0060537 110 0.217
Mouse
cardiac muscle tissue development GO:0048738 48 0.209
Mouse
striated muscle tissue development GO:0014706 110 0.194
Mouse
heart contraction GO:0060047 71 0.181
regulation of muscle contraction GO:0006937 3 0.148
sodium ion transmembrane transport GO:0035725 21 0.140
heart morphogenesis GO:0003007 156 0.134
determination of bilateral symmetry GO:0009855 204 0.132
embryonic organ development GO:0048568 381 0.126
cardiac muscle cell differentiation GO:0055007 30 0.123
Mouse
system process GO:0003008 185 0.120
heart looping GO:0001947 94 0.114
sodium ion transport GO:0006814 24 0.113
cardiac cell development GO:0055006 21 0.103
Mouse
cellular component morphogenesis GO:0032989 336 0.099
specification of symmetry GO:0009799 204 0.096
regulation of multicellular organismal process GO:0051239 277 0.095
blood circulation GO:0008015 87 0.095
cellular component assembly involved in morphogenesis GO:0010927 107 0.094
regulation of blood circulation GO:1903522 32 0.092
cardiac muscle cell development GO:0055013 20 0.092
Mouse
cardiac conduction GO:0061337 3 0.092
actin filament based movement GO:0030048 1 0.091
single organism organelle organization GO:1902589 199 0.084
transmembrane transport GO:0055085 120 0.083
regulation of heart contraction GO:0008016 32 0.082
muscle cell differentiation GO:0042692 139 0.081
Mouse
heart process GO:0003015 71 0.078
striated muscle cell differentiation GO:0051146 129 0.078
Mouse
larval development GO:0002164 2 0.077
head development GO:0060322 303 0.072
muscle structure development GO:0061061 196 0.070
Mouse
organelle assembly GO:0070925 110 0.069
cation transmembrane transport GO:0098655 65 0.069
circulatory system process GO:0003013 87 0.066
calcium ion import GO:0070509 4 0.066
striated muscle cell development GO:0055002 108 0.065
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.063
morphogenesis of an epithelium GO:0002009 333 0.061
tube morphogenesis GO:0035239 349 0.058
positive regulation of blood circulation GO:1903524 2 0.055
transport GO:0006810 220 0.054
organelle organization GO:0006996 227 0.053
ventricular cardiac muscle tissue development GO:0003229 3 0.052
cellular component biogenesis GO:0044085 178 0.051
cardiac myofibril assembly GO:0055003 9 0.049
brain development GO:0007420 293 0.048
cellular component assembly GO:0022607 170 0.047
sensory organ development GO:0007423 393 0.046
embryonic heart tube development GO:0035050 133 0.046
determination of heart left right asymmetry GO:0061371 117 0.045
myofibril assembly GO:0030239 48 0.045
inorganic ion transmembrane transport GO:0098660 57 0.045
monovalent inorganic cation transport GO:0015672 42 0.044
neuron differentiation GO:0030182 353 0.044
sarcomere organization GO:0045214 26 0.043
cardiocyte differentiation GO:0035051 44 0.041
Mouse
positive regulation of heart contraction GO:0045823 2 0.040
regulation of multicellular organismal development GO:2000026 223 0.040
regulation of epithelial cell proliferation GO:0050678 3 0.040
cation transport GO:0006812 81 0.040
regulation of synaptic plasticity GO:0048167 1 0.039
aging GO:0007568 2 0.039
regulation of blood pressure GO:0008217 1 0.039
determination of left right symmetry GO:0007368 179 0.038
regulation of heart rate GO:0002027 5 0.037
positive regulation of cellular component biogenesis GO:0044089 3 0.036
ion transport GO:0006811 114 0.035
regulation of nucleoside metabolic process GO:0009118 2 0.035
inorganic cation transmembrane transport GO:0098662 50 0.035
regulation of neural precursor cell proliferation GO:2000177 3 0.035
heterocycle metabolic process GO:0046483 290 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.034
maintenance of location GO:0051235 4 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
single organism localization GO:1902578 225 0.034
regulation of biological quality GO:0065008 263 0.033
regulation of membrane repolarization GO:0060306 1 0.033
muscle cell development GO:0055001 115 0.033
Mouse
actomyosin structure organization GO:0031032 53 0.033
regulation of tube size GO:0035150 2 0.033
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.033
meiotic nuclear division GO:0007126 4 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
central nervous system development GO:0007417 387 0.032
lipid storage GO:0019915 1 0.032
cytoskeleton organization GO:0007010 96 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
positive regulation of catabolic process GO:0009896 4 0.030
stem cell proliferation GO:0072089 4 0.030
single organism metabolic process GO:0044710 217 0.030
regulation of response to stimulus GO:0048583 269 0.030
positive regulation of transport GO:0051050 2 0.030
locomotion GO:0040011 313 0.029
positive regulation of cell cycle GO:0045787 3 0.029
actin cytoskeleton organization GO:0030036 63 0.029
regulation of system process GO:0044057 40 0.029
regulation of developmental process GO:0050793 247 0.029
regulation of sodium ion transport GO:0002028 2 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.027
blood vessel development GO:0001568 246 0.027
muscle contraction GO:0006936 18 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
nucleic acid metabolic process GO:0090304 244 0.026
actin filament based process GO:0030029 64 0.026
regulation of stem cell proliferation GO:0072091 2 0.026
cell projection morphogenesis GO:0048858 244 0.026
neuron development GO:0048666 262 0.025
signal transduction GO:0007165 455 0.025
cell part morphogenesis GO:0032990 246 0.024
amine metabolic process GO:0009308 2 0.024
cell morphogenesis GO:0000902 289 0.024
aorta morphogenesis GO:0035909 3 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.024
tissue remodeling GO:0048771 4 0.023
chemosensory behavior GO:0007635 1 0.023
establishment of localization GO:0051234 244 0.023
single organism transport GO:0044765 206 0.023
neuron projection morphogenesis GO:0048812 161 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
gtp catabolic process GO:0006184 2 0.023
meiotic cell cycle process GO:1903046 3 0.023
actin mediated cell contraction GO:0070252 1 0.023
regulation of signaling GO:0023051 235 0.022
negative regulation of neural precursor cell proliferation GO:2000178 1 0.022
response to alkaloid GO:0043279 2 0.022
regulation of gene expression GO:0010468 265 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
multicellular organismal signaling GO:0035637 22 0.022
cell projection organization GO:0030030 284 0.022
blood vessel morphogenesis GO:0048514 216 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
membrane repolarization GO:0086009 2 0.021
striated muscle contraction GO:0006941 12 0.020
spermatid differentiation GO:0048515 2 0.020
transcription dna templated GO:0006351 181 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
cytosolic calcium ion transport GO:0060401 3 0.020
muscle organ development GO:0007517 101 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
rna metabolic process GO:0016070 219 0.020
photoreceptor cell fate commitment GO:0046552 1 0.020
cytokinesis GO:0000910 3 0.019
gene expression GO:0010467 252 0.019
nucleic acid templated transcription GO:0097659 181 0.019
cellular amine metabolic process GO:0044106 2 0.019
neurotransmitter transport GO:0006836 2 0.019
response to topologically incorrect protein GO:0035966 2 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
ion transmembrane transport GO:0034220 91 0.019
regulation of protein transport GO:0051223 3 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
ventricular cardiac myofibril assembly GO:0055005 4 0.019
organonitrogen compound metabolic process GO:1901564 74 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
protein dephosphorylation GO:0006470 3 0.018
calcium ion transport into cytosol GO:0060402 3 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
response to stress GO:0006950 263 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of apoptotic process GO:0042981 98 0.018
gtp metabolic process GO:0046039 4 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
positive regulation of biological process GO:0048518 253 0.018
organic acid metabolic process GO:0006082 31 0.018
sensory perception of pain GO:0019233 1 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of striated muscle contraction GO:0006942 2 0.018
regulation of synapse assembly GO:0051963 3 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
regulation of metal ion transport GO:0010959 4 0.017
regulation of metabolic process GO:0019222 359 0.017
digestive tract development GO:0048565 265 0.017
sleep GO:0030431 1 0.017
organic substance biosynthetic process GO:1901576 289 0.017
cellular component movement GO:0006928 335 0.017
dna templated transcription initiation GO:0006352 1 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
smooth muscle contraction GO:0006939 2 0.017
adherens junction organization GO:0034332 4 0.017
negative regulation of signaling GO:0023057 96 0.017
regulation of cell communication GO:0010646 232 0.017
cellular macromolecule metabolic process GO:0044260 391 0.016
protein metabolic process GO:0019538 183 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
compound eye development GO:0048749 2 0.016
regulation of neurogenesis GO:0050767 87 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
rna biosynthetic process GO:0032774 181 0.016
regulation of protein complex assembly GO:0043254 3 0.016
muscle system process GO:0003012 20 0.016
neurological system process GO:0050877 62 0.015
multi organism process GO:0051704 134 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
amino acid transport GO:0006865 2 0.015
stem cell maintenance GO:0019827 4 0.015
protein import GO:0017038 3 0.015
regulation of actin filament based movement GO:1903115 1 0.015
negative regulation of cell communication GO:0010648 96 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
adult behavior GO:0030534 2 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
lipid catabolic process GO:0016042 4 0.014
negative regulation of biological process GO:0048519 304 0.014
metal ion transport GO:0030001 58 0.014
nuclear import GO:0051170 3 0.014
regulation of cardiac muscle contraction GO:0055117 2 0.014
vasculature development GO:0001944 278 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of transport GO:0051049 45 0.014
atrial cardiac myofibril assembly GO:0055004 2 0.014
neurotransmitter secretion GO:0007269 2 0.014
axon guidance GO:0007411 86 0.014
angiogenesis GO:0001525 158 0.014
apoptotic process GO:0006915 116 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
sensory organ morphogenesis GO:0090596 200 0.014
action potential GO:0001508 19 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
biosynthetic process GO:0009058 294 0.014
positive regulation of secretion GO:0051047 1 0.013
response to chemical GO:0042221 320 0.013
rna localization GO:0006403 4 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
fatty acid catabolic process GO:0009062 1 0.013
spermatid development GO:0007286 2 0.013
atrial cardiac muscle cell development GO:0055014 4 0.013
embryonic skeletal joint development GO:0072498 3 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
chordate embryonic development GO:0043009 271 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
cardiac chamber formation GO:0003207 4 0.013
regulation of cardiac muscle cell contraction GO:0086004 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
homeostatic process GO:0042592 142 0.013
eye development GO:0001654 277 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
ventricular cardiac muscle cell development GO:0055015 5 0.013
regulation of protein targeting GO:1903533 2 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
regulation of transporter activity GO:0032409 2 0.013
cell death GO:0008219 121 0.013
hormone secretion GO:0046879 2 0.013
protein targeting to nucleus GO:0044744 3 0.013
nuclear transport GO:0051169 4 0.013
programmed cell death GO:0012501 119 0.012
cognition GO:0050890 1 0.012
neuron projection development GO:0031175 180 0.012
cardiac muscle cell contraction GO:0086003 1 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
eye morphogenesis GO:0048592 144 0.012
renal system development GO:0072001 94 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
cellular biosynthetic process GO:0044249 286 0.012
regulation of cellular response to oxidative stress GO:1900407 2 0.012
small molecule catabolic process GO:0044282 3 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
exocytosis GO:0006887 1 0.012
gland development GO:0048732 143 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of cellular component organization GO:0051128 86 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
cell fate specification GO:0001708 68 0.012
autophagy GO:0006914 4 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
ventricular cardiac muscle cell differentiation GO:0055012 6 0.012
mitotic cell cycle embryonic GO:0045448 2 0.012
cellular response to oxygen levels GO:0071453 1 0.012
growth GO:0040007 174 0.012
regulation of protein catabolic process GO:0042176 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
developmental growth GO:0048589 166 0.011
regulation of epidermis development GO:0045682 2 0.011
hatching GO:0035188 4 0.011
meiotic chromosome segregation GO:0045132 3 0.011
leukocyte proliferation GO:0070661 1 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
notochord cell differentiation GO:0060034 18 0.011
pharyngeal muscle development GO:0043282 4 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
regulation of cell differentiation GO:0045595 142 0.011
cellular localization GO:0051641 97 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
notochord development GO:0030903 54 0.011
regulation of neurological system process GO:0031644 2 0.011
protein import into nucleus GO:0006606 3 0.011
skeletal muscle organ development GO:0060538 78 0.011
regulation of cell activation GO:0050865 1 0.011
startle response GO:0001964 4 0.011
kidney development GO:0001822 92 0.011
regulation of signal transduction GO:0009966 225 0.011
cellular response to external stimulus GO:0071496 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
cardiac muscle contraction GO:0060048 6 0.011
secondary metabolic process GO:0019748 3 0.011
mesenchyme development GO:0060485 127 0.011
protein heterooligomerization GO:0051291 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of protein localization to nucleus GO:1900180 2 0.010
protein secretion GO:0009306 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
cartilage development GO:0051216 96 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of ion transport GO:0043269 22 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
cell matrix adhesion GO:0007160 4 0.010
response to wounding GO:0009611 116 0.010
fin development GO:0033333 77 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
sodium ion import GO:0097369 3 0.010
tube closure GO:0060606 1 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
regulation of membrane potential GO:0042391 23 0.010
wnt signaling pathway GO:0016055 80 0.010
phosphorus metabolic process GO:0006793 109 0.010
mitotic cytokinesis GO:0000281 3 0.010
protein localization to nucleus GO:0034504 3 0.010
response to external stimulus GO:0009605 264 0.010
detection of mechanical stimulus GO:0050982 11 0.010
cilium assembly GO:0042384 58 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
endocrine process GO:0050886 2 0.010
intracellular signal transduction GO:0035556 85 0.010
pronephros morphogenesis GO:0072114 14 0.010
negative regulation of cellular process GO:0048523 283 0.010

lrrc10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.076
cardiovascular system disease DOID:1287 0 0.076
hypertrophic cardiomyopathy DOID:11984 0 0.057
myopathy DOID:423 0 0.057
muscular disease DOID:0080000 0 0.057
heart disease DOID:114 0 0.057
cardiomyopathy DOID:0050700 0 0.057
intrinsic cardiomyopathy DOID:0060036 0 0.057
musculoskeletal system disease DOID:17 0 0.057
muscle tissue disease DOID:66 0 0.057
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.011