Danio rerio

34 known processes

lum

lumican

(Aliases: zgc:86661)

lum biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.430
immune system process GO:0002376 241 0.194
rna biosynthetic process GO:0032774 181 0.181
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.175
Mouse
larval development GO:0002164 2 0.171
regulation of rna biosynthetic process GO:2001141 213 0.170
Mouse
regulation of gene expression GO:0010468 265 0.164
Mouse
sensory organ development GO:0007423 393 0.161
neuron differentiation GO:0030182 353 0.156
gene expression GO:0010467 252 0.156
Mouse
cell substrate adhesion GO:0031589 4 0.153
regulation of establishment of protein localization GO:0070201 4 0.145
nitrogen compound metabolic process GO:0006807 319 0.137
Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.135
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.133
Mouse
signal transduction GO:0007165 455 0.131
response to drug GO:0042493 3 0.123
generation of neurons GO:0048699 385 0.120
morphogenesis of an epithelium GO:0002009 333 0.118
Zebrafish
rna metabolic process GO:0016070 219 0.117
Mouse
aging GO:0007568 2 0.116
myotube differentiation GO:0014902 45 0.115
nucleobase containing compound biosynthetic process GO:0034654 205 0.114
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.112
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.111
Mouse
positive regulation of programmed cell death GO:0043068 29 0.105
muscle cell differentiation GO:0042692 139 0.105
regulation of biosynthetic process GO:0009889 250 0.102
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.100
nucleic acid metabolic process GO:0090304 244 0.100
Mouse
neuron development GO:0048666 262 0.095
regulation of signaling GO:0023051 235 0.094
vasculature development GO:0001944 278 0.091
specification of symmetry GO:0009799 204 0.088
skeletal muscle organ development GO:0060538 78 0.087
programmed cell death GO:0012501 119 0.087
digestive tract morphogenesis GO:0048546 231 0.086
single organism metabolic process GO:0044710 217 0.086
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.084
Mouse
multicellular organismal signaling GO:0035637 22 0.082
aromatic compound biosynthetic process GO:0019438 217 0.081
Mouse
cell matrix adhesion GO:0007160 4 0.081
regulation of developmental process GO:0050793 247 0.080
regulation of cell substrate adhesion GO:0010810 1 0.079
regulation of stem cell proliferation GO:0072091 2 0.079
regulation of cellular biosynthetic process GO:0031326 245 0.076
Mouse
positive regulation of biological process GO:0048518 253 0.076
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.076
Mouse
regulation of protein transport GO:0051223 3 0.075
digestive tract development GO:0048565 265 0.074
regulation of metabolic process GO:0019222 359 0.072
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.070
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.069
Mouse
blood vessel development GO:0001568 246 0.067
regulation of signal transduction GO:0009966 225 0.065
embryonic organ morphogenesis GO:0048562 274 0.065
organic acid metabolic process GO:0006082 31 0.065
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.064
meiotic nuclear division GO:0007126 4 0.063
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
Mouse
regulation of response to stimulus GO:0048583 269 0.062
regulation of apoptotic process GO:0042981 98 0.061
heterocycle metabolic process GO:0046483 290 0.061
Mouse
negative regulation of biological process GO:0048519 304 0.060
response to external stimulus GO:0009605 264 0.059
stem cell proliferation GO:0072089 4 0.059
regulation of multicellular organismal process GO:0051239 277 0.059
cellular aromatic compound metabolic process GO:0006725 295 0.059
Mouse
cellular component morphogenesis GO:0032989 336 0.058
cellular response to extracellular stimulus GO:0031668 2 0.057
cellular biosynthetic process GO:0044249 286 0.057
Mouse
cellular amine metabolic process GO:0044106 2 0.057
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.057
nucleic acid templated transcription GO:0097659 181 0.056
Mouse
death GO:0016265 121 0.055
cognition GO:0050890 1 0.055
positive regulation of cell adhesion GO:0045785 1 0.054
hemopoiesis GO:0030097 183 0.054
positive regulation of transport GO:0051050 2 0.054
muscle fiber development GO:0048747 52 0.052
digestive system development GO:0055123 289 0.052
immune system development GO:0002520 191 0.051
positive regulation of cellular component biogenesis GO:0044089 3 0.051
protein metabolic process GO:0019538 183 0.050
Zebrafish
taxis GO:0042330 109 0.050
peptidyl serine phosphorylation GO:0018105 1 0.050
cellular component assembly GO:0022607 170 0.049
growth GO:0040007 174 0.049
Zebrafish
oxoacid metabolic process GO:0043436 31 0.049
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.049
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.049
Mouse
cell projection morphogenesis GO:0048858 244 0.048
cellular amino acid metabolic process GO:0006520 7 0.048
cell proliferation GO:0008283 80 0.048
negative regulation of macromolecule metabolic process GO:0010605 76 0.048
cellular ketone metabolic process GO:0042180 11 0.048
cell death GO:0008219 121 0.047
regulation of multicellular organismal development GO:2000026 223 0.047
striated muscle cell differentiation GO:0051146 129 0.047
cell migration GO:0016477 237 0.047
heart development GO:0007507 313 0.047
cell motility GO:0048870 244 0.047
negative regulation of metabolic process GO:0009892 86 0.045
cell fate commitment GO:0045165 99 0.045
negative regulation of protein phosphorylation GO:0001933 4 0.045
apoptotic process GO:0006915 116 0.044
determination of heart left right asymmetry GO:0061371 117 0.044
amine metabolic process GO:0009308 2 0.043
positive regulation of gene expression GO:0010628 71 0.043
Mouse
neuron projection morphogenesis GO:0048812 161 0.043
regulation of transcription dna templated GO:0006355 213 0.043
Mouse
transcription dna templated GO:0006351 181 0.042
Mouse
nuclear transport GO:0051169 4 0.042
regulation of cellular metabolic process GO:0031323 320 0.042
Mouse
response to stress GO:0006950 263 0.041
tube morphogenesis GO:0035239 349 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.040
response to ketone GO:1901654 1 0.039
regulation of cell communication GO:0010646 232 0.039
regulation of cytoplasmic transport GO:1903649 4 0.039
hematopoietic or lymphoid organ development GO:0048534 191 0.038
skeletal muscle tissue development GO:0007519 67 0.038
embryonic heart tube morphogenesis GO:0003143 108 0.038
determination of bilateral symmetry GO:0009855 204 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
Mouse
peptidyl serine modification GO:0018209 2 0.038
muscle cell development GO:0055001 115 0.038
cellular component biogenesis GO:0044085 178 0.037
homeostatic process GO:0042592 142 0.037
phagocytosis GO:0006909 3 0.036
gastrulation GO:0007369 208 0.036
autophagy GO:0006914 4 0.036
response to light stimulus GO:0009416 46 0.036
small gtpase mediated signal transduction GO:0007264 8 0.036
positive regulation of cell substrate adhesion GO:0010811 1 0.035
positive regulation of cellular process GO:0048522 201 0.035
Mouse
muscle structure development GO:0061061 196 0.035
cellular response to external stimulus GO:0071496 2 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
muscle organ development GO:0007517 101 0.035
urogenital system development GO:0001655 97 0.034
gland development GO:0048732 143 0.034
regulation of programmed cell death GO:0043067 101 0.034
regulation of cell differentiation GO:0045595 142 0.033
glial cell migration GO:0008347 3 0.033
muscle tissue development GO:0060537 110 0.033
heart morphogenesis GO:0003007 156 0.033
transmission of nerve impulse GO:0019226 19 0.033
organic substance biosynthetic process GO:1901576 289 0.033
Mouse
cellular component movement GO:0006928 335 0.033
positive regulation of cell death GO:0010942 29 0.032
regulation of protein targeting GO:1903533 2 0.032
brain development GO:0007420 293 0.032
multicellular organism growth GO:0035264 4 0.032
cell projection organization GO:0030030 284 0.031
blood vessel morphogenesis GO:0048514 216 0.031
positive regulation of leukocyte migration GO:0002687 2 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
regulation of epithelial cell proliferation GO:0050678 3 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
neuronal action potential GO:0019228 18 0.031
macromolecule biosynthetic process GO:0009059 227 0.030
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
stem cell maintenance GO:0019827 4 0.030
negative regulation of cell communication GO:0010648 96 0.030
system process GO:0003008 185 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
Mouse
epithelial tube morphogenesis GO:0060562 148 0.029
myelination GO:0042552 18 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.029
myotube cell development GO:0014904 35 0.029
neurological system process GO:0050877 62 0.029
negative regulation of protein transport GO:0051224 3 0.029
regulation of neurogenesis GO:0050767 87 0.028
biosynthetic process GO:0009058 294 0.028
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
eye development GO:0001654 277 0.027
developmental growth GO:0048589 166 0.027
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.027
response to carbohydrate GO:0009743 3 0.026
regulation of cell cycle GO:0051726 52 0.026
lipid storage GO:0019915 1 0.026
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
positive regulation of wound healing GO:0090303 1 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
cellular protein metabolic process GO:0044267 129 0.025
skeletal system morphogenesis GO:0048705 102 0.025
regulation of nervous system development GO:0051960 90 0.025
regulation of dendrite development GO:0050773 3 0.024
cellular protein modification process GO:0006464 100 0.024
response to abiotic stimulus GO:0009628 122 0.024
germ line stem cell maintenance GO:0030718 2 0.024
establishment of protein localization to plasma membrane GO:0090002 1 0.024
negative regulation of signaling GO:0023057 96 0.024
small molecule metabolic process GO:0044281 77 0.024
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.024
Zebrafish Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.023
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.023
Mouse
transport GO:0006810 220 0.023
phosphorylation GO:0016310 69 0.023
lateral inhibition GO:0046331 1 0.023
cellular response to nutrient levels GO:0031669 2 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.023
adult behavior GO:0030534 2 0.023
response to chemical GO:0042221 320 0.023
Rat
regulation of reproductive process GO:2000241 4 0.022
cellular response to reactive oxygen species GO:0034614 2 0.022
regulation of dna replication GO:0006275 3 0.022
organelle organization GO:0006996 227 0.022
negative regulation of apoptotic process GO:0043066 55 0.021
regulation of cell matrix adhesion GO:0001952 1 0.021
regulation of calcium ion transport GO:0051924 2 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
positive regulation of cytokine production GO:0001819 2 0.021
regulation of cell activation GO:0050865 1 0.021
maintenance of location GO:0051235 4 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
negative regulation of cell death GO:0060548 60 0.021
positive regulation of metabolic process GO:0009893 108 0.021
Mouse
mesenchymal cell proliferation GO:0010463 1 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.020
locomotion GO:0040011 313 0.020
negative regulation of kinase activity GO:0033673 4 0.020
localization of cell GO:0051674 244 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
Mouse
response to hexose GO:0009746 3 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
cellular response to topologically incorrect protein GO:0035967 2 0.020
response to uv GO:0009411 3 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.020
negative regulation of gene expression GO:0010629 65 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of cell death GO:0010941 103 0.019
negative regulation of cytokine production GO:0001818 1 0.019
positive regulation of stem cell proliferation GO:2000648 1 0.019
regulation of rna metabolic process GO:0051252 224 0.019
Mouse
protein dephosphorylation GO:0006470 3 0.019
action potential GO:0001508 19 0.019
myeloid cell differentiation GO:0030099 86 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
protein localization to nucleus GO:0034504 3 0.019
axon development GO:0061564 166 0.018
response to nutrient GO:0007584 3 0.018
heart process GO:0003015 71 0.018
protein homooligomerization GO:0051260 3 0.018
ameboidal type cell migration GO:0001667 143 0.018
granulocyte migration GO:0097530 11 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
regulation of cell proliferation GO:0042127 37 0.018
regulation of synapse organization GO:0050807 3 0.018
cell adhesion GO:0007155 40 0.018
leukocyte migration GO:0050900 15 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
Mouse
cell cycle GO:0007049 93 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
multi organism process GO:0051704 134 0.017
chemotaxis GO:0006935 104 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
regulation of protein metabolic process GO:0051246 56 0.017
single organism localization GO:1902578 225 0.017
regulation of protein complex assembly GO:0043254 3 0.017
response to monosaccharide GO:0034284 3 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of cellular component organization GO:0051128 86 0.017
ras protein signal transduction GO:0007265 7 0.017
neuron projection development GO:0031175 180 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
regulation of cytokine production GO:0001817 3 0.017
homeostasis of number of cells GO:0048872 62 0.017
gtp metabolic process GO:0046039 4 0.017
biological adhesion GO:0022610 40 0.017
regulation of metal ion transport GO:0010959 4 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
organelle assembly GO:0070925 110 0.017
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.016
negative regulation of signal transduction GO:0009968 94 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
skeletal muscle fiber development GO:0048741 35 0.016
locomotor rhythm GO:0045475 3 0.016
axon extension GO:0048675 45 0.016
protein targeting to nucleus GO:0044744 3 0.016
axonogenesis GO:0007409 152 0.016
regulation of rho protein signal transduction GO:0035023 2 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
striated muscle tissue development GO:0014706 110 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.015
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of biological quality GO:0065008 263 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
adherens junction organization GO:0034332 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of membrane potential GO:0042391 23 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
camera type eye development GO:0043010 222 0.015
regulation of proteolysis GO:0030162 24 0.015
peptidyl threonine modification GO:0018210 1 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
Mouse
positive regulation of map kinase activity GO:0043406 3 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
positive regulation of cellular component movement GO:0051272 11 0.015
response to glucose GO:0009749 3 0.015
regulation of molecular function GO:0065009 70 0.015
response to corticosteroid GO:0031960 1 0.015
protein secretion GO:0009306 1 0.015
regulation of cell migration GO:0030334 40 0.015
protein localization to plasma membrane GO:0072659 1 0.015
heart looping GO:0001947 94 0.015
negative regulation of ras protein signal transduction GO:0046580 1 0.015
striated muscle cell development GO:0055002 108 0.015
multicellular organismal macromolecule metabolic process GO:0044259 2 0.015
behavior GO:0007610 74 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
sensory organ morphogenesis GO:0090596 200 0.015
tissue remodeling GO:0048771 4 0.014
regulation of response to external stimulus GO:0032101 31 0.014
protein phosphorylation GO:0006468 47 0.014
cell part morphogenesis GO:0032990 246 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
cell morphogenesis GO:0000902 289 0.014
establishment of localization in cell GO:0051649 77 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
response to glucocorticoid GO:0051384 1 0.014
neuron projection extension GO:1990138 45 0.014
gtp catabolic process GO:0006184 2 0.014
mitochondrion organization GO:0007005 4 0.014
determination of left right symmetry GO:0007368 179 0.014
ensheathment of neurons GO:0007272 18 0.013
regulation of growth GO:0040008 42 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
head development GO:0060322 303 0.013
cell substrate junction assembly GO:0007044 2 0.013
positive regulation of apoptotic process GO:0043065 29 0.013
regulation of collagen metabolic process GO:0010712 2 0.013
regulation of organelle organization GO:0033043 29 0.013
spermatid differentiation GO:0048515 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
negative regulation of transcription dna templated GO:0045892 45 0.013
embryonic heart tube development GO:0035050 133 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
circulatory system process GO:0003013 87 0.013
glucose homeostasis GO:0042593 1 0.013
rho protein signal transduction GO:0007266 5 0.013
single organism biosynthetic process GO:0044711 71 0.013
nuclear import GO:0051170 3 0.013
regulation of bmp signaling pathway GO:0030510 39 0.013
positive regulation of leukocyte chemotaxis GO:0002690 1 0.013
liver development GO:0001889 96 0.013
membrane invagination GO:0010324 1 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
axon ensheathment GO:0008366 18 0.012
regulation of catalytic activity GO:0050790 55 0.012
skeletal system development GO:0001501 181 0.012
Zebrafish Rat
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
response to alcohol GO:0097305 14 0.012
establishment of localization GO:0051234 244 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
regulation of transport GO:0051049 45 0.012
meiotic cell cycle process GO:1903046 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
spermatid development GO:0007286 2 0.012
cellular respiration GO:0045333 3 0.012
myeloid leukocyte migration GO:0097529 12 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
single organism transport GO:0044765 206 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
cell projection assembly GO:0030031 64 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
Mouse
response to oxygen levels GO:0070482 25 0.011
response to alkaloid GO:0043279 2 0.011
positive regulation of cell activation GO:0050867 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
bmp signaling pathway GO:0030509 52 0.011
angiogenesis GO:0001525 158 0.011
apoptotic signaling pathway GO:0097190 23 0.011
negative regulation of dna replication GO:0008156 2 0.011
positive regulation of neutrophil migration GO:1902624 0 0.011
macromolecule modification GO:0043412 111 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
protein import GO:0017038 3 0.011
regulation of protein polymerization GO:0032271 2 0.011
gliogenesis GO:0042063 45 0.011
renal system development GO:0072001 94 0.011
response to vitamin GO:0033273 3 0.011
negative regulation of cellular process GO:0048523 283 0.011
protein acylation GO:0043543 3 0.011
negative regulation of developmental process GO:0051093 65 0.011
cellular response to starvation GO:0009267 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
heart contraction GO:0060047 71 0.011
regulation of cell development GO:0060284 100 0.011
stem cell differentiation GO:0048863 117 0.011
central nervous system development GO:0007417 387 0.011
lipid biosynthetic process GO:0008610 22 0.011
response to inorganic substance GO:0010035 38 0.011
positive regulation of cell migration GO:0030335 11 0.011
response to hydrogen peroxide GO:0042542 3 0.010
eye morphogenesis GO:0048592 144 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
regulation of gtpase activity GO:0043087 2 0.010
stem cell division GO:0017145 1 0.010
cell growth GO:0016049 57 0.010
positive regulation of multicellular organismal process GO:0051240 52 0.010
regulation of myotube differentiation GO:0010830 2 0.010
camera type eye morphogenesis GO:0048593 108 0.010
metal ion transport GO:0030001 58 0.010
myeloid cell homeostasis GO:0002262 56 0.010

lum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010