Danio rerio

31 known processes

m6pr

mannose-6-phosphate receptor (cation dependent)

(Aliases: MPR46,zgc:77757,wu:fj81h11)

m6pr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 313 0.217
larval development GO:0002164 2 0.151
localization of cell GO:0051674 244 0.150
immune system development GO:0002520 191 0.117
regulation of biological quality GO:0065008 263 0.090
chordate embryonic development GO:0043009 271 0.081
heart development GO:0007507 313 0.074
regulation of multicellular organism growth GO:0040014 4 0.071
meiosis i GO:0007127 1 0.070
modification dependent macromolecule catabolic process GO:0043632 3 0.066
cell motility GO:0048870 244 0.063
aging GO:0007568 2 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.055
brain development GO:0007420 293 0.055
maintenance of location GO:0051235 4 0.053
b cell differentiation GO:0030183 1 0.052
cellular component movement GO:0006928 335 0.050
cellular protein catabolic process GO:0044257 4 0.048
lipid storage GO:0019915 1 0.047
cellular response to nutrient levels GO:0031669 2 0.047
cellular macromolecule metabolic process GO:0044260 391 0.046
cell cycle g1 s phase transition GO:0044843 1 0.044
hemopoiesis GO:0030097 183 0.043
cell aging GO:0007569 2 0.040
negative regulation of biological process GO:0048519 304 0.039
positive regulation of transport GO:0051050 2 0.039
homeostatic process GO:0042592 142 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
cell migration GO:0016477 237 0.037
cell projection organization GO:0030030 284 0.037
convergent extension involved in organogenesis GO:0060029 10 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.036
establishment of localization GO:0051234 244 0.036
single organism intracellular transport GO:1902582 25 0.035
tube morphogenesis GO:0035239 349 0.035
positive regulation of cell cycle GO:0045787 3 0.034
cellular response to stress GO:0033554 62 0.033
proteasomal protein catabolic process GO:0010498 2 0.032
cellular response to external stimulus GO:0071496 2 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
single organism membrane fusion GO:0044801 2 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
meiotic spindle organization GO:0000212 1 0.029
central nervous system development GO:0007417 387 0.029
modification dependent protein catabolic process GO:0019941 3 0.028
signal transduction GO:0007165 455 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
protein modification process GO:0036211 100 0.027
gastrulation GO:0007369 208 0.027
mitochondrion organization GO:0007005 4 0.027
organic acid metabolic process GO:0006082 31 0.027
b cell activation GO:0042113 2 0.027
regulation of localization GO:0032879 104 0.027
multicellular organism growth GO:0035264 4 0.027
membrane fusion GO:0061025 2 0.027
positive regulation of map kinase activity GO:0043406 3 0.026
meiotic cell cycle process GO:1903046 3 0.026
transport GO:0006810 220 0.025
epithelial tube morphogenesis GO:0060562 148 0.024
myeloid cell development GO:0061515 32 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
single organism metabolic process GO:0044710 217 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
oxoacid metabolic process GO:0043436 31 0.023
forebrain cell migration GO:0021885 1 0.023
single organism localization GO:1902578 225 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
cellular response to oxygen levels GO:0071453 1 0.023
organelle fusion GO:0048284 3 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.022
head development GO:0060322 303 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
female meiotic division GO:0007143 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.020
heart looping GO:0001947 94 0.020
regulation of cell activation GO:0050865 1 0.020
cellular protein metabolic process GO:0044267 129 0.020
positive regulation of apoptotic process GO:0043065 29 0.020
macromolecule modification GO:0043412 111 0.020
embryonic organ development GO:0048568 381 0.020
single organism organelle organization GO:1902589 199 0.020
meiotic nuclear division GO:0007126 4 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
cellular response to dna damage stimulus GO:0006974 24 0.019
spindle assembly involved in meiosis GO:0090306 1 0.019
response to stress GO:0006950 263 0.019
single organism nuclear import GO:1902593 3 0.019
leukocyte homeostasis GO:0001776 2 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
heterocycle metabolic process GO:0046483 290 0.019
microtubule cytoskeleton organization GO:0000226 33 0.019
growth GO:0040007 174 0.019
convergent extension GO:0060026 118 0.018
developmental growth GO:0048589 166 0.018
regulation of membrane potential GO:0042391 23 0.018
regulation of metal ion transport GO:0010959 4 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
positive regulation of neuron death GO:1901216 1 0.017
response to chemical GO:0042221 320 0.017
behavior GO:0007610 74 0.017
exocytosis GO:0006887 1 0.017
cellular component morphogenesis GO:0032989 336 0.017
response to glucocorticoid GO:0051384 1 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
determination of heart left right asymmetry GO:0061371 117 0.016
heart morphogenesis GO:0003007 156 0.016
chemical homeostasis GO:0048878 49 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
hatching GO:0035188 4 0.016
adult behavior GO:0030534 2 0.016
regulation of protein transport GO:0051223 3 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of cell proliferation GO:0042127 37 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
metal ion homeostasis GO:0055065 26 0.015
organism emergence from protective structure GO:0071684 4 0.015
programmed cell death GO:0012501 119 0.015
lymphocyte homeostasis GO:0002260 1 0.015
regulation of glial cell differentiation GO:0045685 4 0.015
regulation of cellular component organization GO:0051128 86 0.015
amine metabolic process GO:0009308 2 0.015
death GO:0016265 121 0.015
regulation of cell development GO:0060284 100 0.015
positive regulation of biological process GO:0048518 253 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
regionalization GO:0003002 274 0.014
nitric oxide metabolic process GO:0046209 2 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
pancreas development GO:0031016 84 0.014
nucleic acid metabolic process GO:0090304 244 0.014
ion homeostasis GO:0050801 41 0.014
regulation of exocytosis GO:0017157 1 0.014
myeloid cell homeostasis GO:0002262 56 0.014
activation of mapk activity GO:0000187 3 0.014
cytoskeleton organization GO:0007010 96 0.014
mononuclear cell proliferation GO:0032943 1 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
regulation of organ growth GO:0046620 3 0.014
immune system process GO:0002376 241 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
double strand break repair GO:0006302 3 0.013
regulation of cell death GO:0010941 103 0.013
hormone secretion GO:0046879 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of apoptotic process GO:0042981 98 0.013
digestive system development GO:0055123 289 0.013
glial cell migration GO:0008347 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
apoptotic process GO:0006915 116 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
specification of symmetry GO:0009799 204 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
mitotic cell cycle process GO:1903047 48 0.012
positive regulation of catabolic process GO:0009896 4 0.012
regulation of synapse assembly GO:0051963 3 0.012
peptide metabolic process GO:0006518 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
rna metabolic process GO:0016070 219 0.012
nuclear transport GO:0051169 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
small molecule metabolic process GO:0044281 77 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
lymphocyte proliferation GO:0046651 1 0.012
protein metabolic process GO:0019538 183 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
cell cycle arrest GO:0007050 1 0.012
organelle organization GO:0006996 227 0.012
gland development GO:0048732 143 0.012
autophagy GO:0006914 4 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
atp catabolic process GO:0006200 4 0.012
regulation of reproductive process GO:2000241 4 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
cellular amine metabolic process GO:0044106 2 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
compound eye development GO:0048749 2 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
response to hexose GO:0009746 3 0.011
cell morphogenesis GO:0000902 289 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
cation homeostasis GO:0055080 33 0.011
meiotic chromosome segregation GO:0045132 3 0.011
regulation of developmental process GO:0050793 247 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
rna biosynthetic process GO:0032774 181 0.011
biological adhesion GO:0022610 40 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
cell proliferation GO:0008283 80 0.011
response to corticosteroid GO:0031960 1 0.011
nuclear import GO:0051170 3 0.011
cellular protein modification process GO:0006464 100 0.011
sequestering of calcium ion GO:0051208 3 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
regulation of primary metabolic process GO:0080090 311 0.011
regulation of signal transduction GO:0009966 225 0.011
cell part morphogenesis GO:0032990 246 0.011
startle response GO:0001964 4 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
negative regulation of reproductive process GO:2000242 3 0.011
single organism reproductive process GO:0044702 40 0.011
cation transport GO:0006812 81 0.011
regulation of synapse organization GO:0050807 3 0.011
regulation of dendrite development GO:0050773 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of oocyte development GO:0060281 3 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of mitochondrion organization GO:0010821 1 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
cytokinesis GO:0000910 3 0.010
regulation of catalytic activity GO:0050790 55 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
neuron differentiation GO:0030182 353 0.010
mitotic cell cycle GO:0000278 64 0.010
system process GO:0003008 185 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
homeostasis of number of cells GO:0048872 62 0.010
cellular localization GO:0051641 97 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010

m6pr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.044
cancer DOID:162 0 0.037
organ system cancer DOID:0050686 0 0.037
gastrointestinal system cancer DOID:3119 0 0.036
muscle tissue disease DOID:66 0 0.018
disease of anatomical entity DOID:7 0 0.018
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
myopathy DOID:423 0 0.018
nervous system disease DOID:863 0 0.013
endocrine gland cancer DOID:170 0 0.011
heart disease DOID:114 0 0.011
cardiomyopathy DOID:0050700 0 0.011
cardiovascular system disease DOID:1287 0 0.011