Danio rerio

0 known processes

map3k4

mitogen activated protein kinase kinase kinase 4

(Aliases: wu:fc83c01,cb135,mekk4,wu:fa02f11)

map3k4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process GO:0009889 250 0.368
signal transduction GO:0007165 455 0.352
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.350
Fly
larval development GO:0002164 2 0.297
nitrogen compound metabolic process GO:0006807 319 0.294
Fly
single organism localization GO:1902578 225 0.288
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.252
regulation of signal transduction GO:0009966 225 0.244
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.231
Human Mouse Fly
protein metabolic process GO:0019538 183 0.214
Human Mouse Fly
nuclear transport GO:0051169 4 0.204
negative regulation of cellular process GO:0048523 283 0.197
Fly
generation of neurons GO:0048699 385 0.197
regulation of cell communication GO:0010646 232 0.185
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.179
cell migration GO:0016477 237 0.178
response to external stimulus GO:0009605 264 0.173
cell surface receptor signaling pathway GO:0007166 325 0.173
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.171
Fly
positive regulation of signaling GO:0023056 56 0.161
Human Mouse Fly
phosphorus metabolic process GO:0006793 109 0.158
Human Mouse Fly
regulation of response to stimulus GO:0048583 269 0.157
Human Mouse Fly
axon development GO:0061564 166 0.156
neuron differentiation GO:0030182 353 0.149
regulation of nitrogen compound metabolic process GO:0051171 251 0.147
Fly
positive regulation of metabolic process GO:0009893 108 0.140
Human Mouse Fly
cellular protein modification process GO:0006464 100 0.137
Human Mouse Fly
gene expression GO:0010467 252 0.137
Mouse
single organism metabolic process GO:0044710 217 0.125
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.122
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.122
protein modification process GO:0036211 100 0.120
Human Mouse Fly
localization of cell GO:0051674 244 0.120
negative regulation of biological process GO:0048519 304 0.118
Fly
axonogenesis GO:0007409 152 0.117
modification dependent protein catabolic process GO:0019941 3 0.115
cell projection organization GO:0030030 284 0.111
single organism organelle organization GO:1902589 199 0.110
cellular protein metabolic process GO:0044267 129 0.110
Human Mouse Fly
protein polyubiquitination GO:0000209 4 0.107
digestive system development GO:0055123 289 0.107
negative regulation of response to stimulus GO:0048585 104 0.105
cellular protein catabolic process GO:0044257 4 0.105
cellular macromolecule biosynthetic process GO:0034645 224 0.105
negative regulation of signal transduction GO:0009968 94 0.105
cell projection morphogenesis GO:0048858 244 0.104
regulation of neurogenesis GO:0050767 87 0.104
nucleocytoplasmic transport GO:0006913 4 0.102
cellular aromatic compound metabolic process GO:0006725 295 0.097
Fly
rna biosynthetic process GO:0032774 181 0.097
cellular nitrogen compound metabolic process GO:0034641 290 0.097
Fly
positive regulation of map kinase activity GO:0043406 3 0.094
Human Mouse Fly
neuroblast proliferation GO:0007405 2 0.091
adult behavior GO:0030534 2 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.090
positive regulation of biological process GO:0048518 253 0.090
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.089
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.088
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.088
Human Mouse Fly
regulation of developmental process GO:0050793 247 0.086
regulation of signaling GO:0023051 235 0.086
Human Mouse Fly
regionalization GO:0003002 274 0.084
protein heterooligomerization GO:0051291 1 0.083
heterocycle metabolic process GO:0046483 290 0.080
Fly
establishment of localization GO:0051234 244 0.078
Fly
negative regulation of collateral sprouting GO:0048671 2 0.078
regulation of neuron projection development GO:0010975 40 0.078
regulation of cellular metabolic process GO:0031323 320 0.077
Human Mouse Fly
establishment of localization in cell GO:0051649 77 0.076
single organism transport GO:0044765 206 0.076
Fly
cell motility GO:0048870 244 0.076
ubiquitin dependent protein catabolic process GO:0006511 3 0.075
nucleobase containing compound metabolic process GO:0006139 274 0.072
Fly
regulation of metabolic process GO:0019222 359 0.072
Human Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.072
Human Mouse Fly
phagocytosis GO:0006909 3 0.070
Fly
regulation of rna biosynthetic process GO:2001141 213 0.068
rna metabolic process GO:0016070 219 0.068
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.068
head development GO:0060322 303 0.068
heart development GO:0007507 313 0.067
oocyte development GO:0048599 14 0.066
positive regulation of transport GO:0051050 2 0.065
protein localization to nucleus GO:0034504 3 0.065
aromatic compound biosynthetic process GO:0019438 217 0.064
brain development GO:0007420 293 0.063
regulation of biological quality GO:0065008 263 0.063
Fly
small molecule metabolic process GO:0044281 77 0.063
cell morphogenesis GO:0000902 289 0.063
biosynthetic process GO:0009058 294 0.063
heart morphogenesis GO:0003007 156 0.062
negative regulation of cell communication GO:0010648 96 0.061
regulation of cellular biosynthetic process GO:0031326 245 0.060
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.060
positive regulation of catalytic activity GO:0043085 25 0.060
Human Mouse Fly
multicellular organism growth GO:0035264 4 0.060
neuron projection development GO:0031175 180 0.059
regulation of nucleic acid templated transcription GO:1903506 213 0.059
epidermis development GO:0008544 48 0.059
regulation of transcription dna templated GO:0006355 213 0.058
regulation of multicellular organismal development GO:2000026 223 0.058
cell cycle GO:0007049 93 0.057
regulation of cell development GO:0060284 100 0.055
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.055
regulation of cell shape GO:0008360 1 0.054
cellular component biogenesis GO:0044085 178 0.054
Fly
organelle organization GO:0006996 227 0.054
Fly
phosphorylation GO:0016310 69 0.052
Human Mouse Fly
developmental growth GO:0048589 166 0.052
developmental growth involved in morphogenesis GO:0060560 86 0.052
regulation of protein metabolic process GO:0051246 56 0.051
Human Mouse Fly
convergent extension GO:0060026 118 0.051
regulation of meiotic cell cycle GO:0051445 1 0.051
aging GO:0007568 2 0.050
stem cell division GO:0017145 1 0.050
cellular component movement GO:0006928 335 0.050
negative regulation of signaling GO:0023057 96 0.049
positive regulation of catabolic process GO:0009896 4 0.049
activation of mapk activity GO:0000187 3 0.048
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.048
non canonical wnt signaling pathway GO:0035567 13 0.047
transport GO:0006810 220 0.047
Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.047
Human Mouse Fly
axon guidance GO:0007411 86 0.047
cellular ketone metabolic process GO:0042180 11 0.046
stem cell proliferation GO:0072089 4 0.046
cellular localization GO:0051641 97 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.046
modification dependent macromolecule catabolic process GO:0043632 3 0.046
negative chemotaxis GO:0050919 1 0.045
protein dephosphorylation GO:0006470 3 0.045
nuclear export GO:0051168 1 0.044
regulation of anatomical structure morphogenesis GO:0022603 130 0.043
regulation of establishment of protein localization GO:0070201 4 0.043
organelle localization GO:0051640 49 0.043
positive regulation of cell communication GO:0010647 56 0.043
Human Mouse Fly
cell migration in hindbrain GO:0021535 7 0.042
cellular amine metabolic process GO:0044106 2 0.042
locomotion GO:0040011 313 0.042
nuclear import GO:0051170 3 0.042
organic substance biosynthetic process GO:1901576 289 0.042
regulation of rna metabolic process GO:0051252 224 0.041
growth GO:0040007 174 0.041
regulation of protein transport GO:0051223 3 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.041
phosphate containing compound metabolic process GO:0006796 108 0.040
Human Mouse Fly
transcription dna templated GO:0006351 181 0.040
regulation of protein targeting GO:1903533 2 0.039
hindbrain development GO:0030902 91 0.039
peptidyl serine phosphorylation GO:0018105 1 0.039
regulation of synapse organization GO:0050807 3 0.039
regulation of intracellular protein transport GO:0033157 3 0.038
oxoacid metabolic process GO:0043436 31 0.038
cellular biosynthetic process GO:0044249 286 0.038
response to vitamin GO:0033273 3 0.038
stem cell maintenance GO:0019827 4 0.038
developmental cell growth GO:0048588 52 0.037
sensory neuron axon guidance GO:0097374 3 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
gastrulation GO:0007369 208 0.036
negative regulation of multicellular organismal process GO:0051241 69 0.036
sexual reproduction GO:0019953 36 0.036
cell part morphogenesis GO:0032990 246 0.036
regulation of glucose import GO:0046324 1 0.035
positive regulation of jnk cascade GO:0046330 3 0.035
Human Mouse Fly
positive regulation of cell cycle GO:0045787 3 0.035
cell fate commitment GO:0045165 99 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
amine metabolic process GO:0009308 2 0.035
regulation of phosphate metabolic process GO:0019220 43 0.035
Human Mouse Fly
cellular response to organic substance GO:0071310 105 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.034
primary neural tube formation GO:0014020 1 0.034
neuron projection morphogenesis GO:0048812 161 0.034
atp catabolic process GO:0006200 4 0.034
intracellular signal transduction GO:0035556 85 0.033
Human Mouse Fly
protein import into nucleus GO:0006606 3 0.033
positive regulation of molecular function GO:0044093 33 0.033
Human Mouse Fly
response to carbohydrate GO:0009743 3 0.033
regulation of catalytic activity GO:0050790 55 0.033
Human Mouse Fly
regulation of stem cell differentiation GO:2000736 4 0.033
regulation of localization GO:0032879 104 0.033
regulation of cell differentiation GO:0045595 142 0.033
response to nutrient GO:0007584 3 0.033
response to organic substance GO:0010033 153 0.032
multi organism process GO:0051704 134 0.032
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
nucleic acid templated transcription GO:0097659 181 0.032
positive regulation of signal transduction GO:0009967 56 0.032
Human Mouse Fly
response to uv GO:0009411 3 0.032
Human
macromolecule biosynthetic process GO:0009059 227 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
regulation of cellular protein metabolic process GO:0032268 52 0.031
Human Mouse Fly
negative regulation of response to cytokine stimulus GO:0060761 2 0.030
skin development GO:0043588 54 0.030
maintenance of location GO:0051235 4 0.030
regulation of reproductive process GO:2000241 4 0.030
regulation of neuron differentiation GO:0045664 56 0.030
single organism cellular localization GO:1902580 46 0.030
response to chemical GO:0042221 320 0.030
Fly
axon cargo transport GO:0008088 2 0.029
positive regulation of stress activated mapk cascade GO:0032874 3 0.029
Human Mouse Fly
response to oxygen containing compound GO:1901700 55 0.029
regulation of nervous system development GO:0051960 90 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
regulation of intracellular signal transduction GO:1902531 57 0.027
Human Mouse Fly
spermatid development GO:0007286 2 0.027
apoptotic process GO:0006915 116 0.027
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
cell cell recognition GO:0009988 1 0.026
death GO:0016265 121 0.026
Fly
regulation of circadian rhythm GO:0042752 4 0.026
single organism nuclear import GO:1902593 3 0.026
protein phosphorylation GO:0006468 47 0.026
Human Mouse Fly
regulation of molecular function GO:0065009 70 0.026
Human Mouse Fly
regulation of dendrite morphogenesis GO:0048814 3 0.026
regulation of mitotic cell cycle embryonic GO:0009794 2 0.026
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
programmed cell death GO:0012501 119 0.025
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
cell substrate adhesion GO:0031589 4 0.025
negative regulation of gene expression GO:0010629 65 0.025
macromolecule modification GO:0043412 111 0.024
Human Mouse Fly
regulation of dendrite development GO:0050773 3 0.024
positive regulation of cellular process GO:0048522 201 0.024
Human Mouse Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
cytoskeleton organization GO:0007010 96 0.024
regulation of phosphorus metabolic process GO:0051174 43 0.023
Human Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
cellular component morphogenesis GO:0032989 336 0.023
neuron migration GO:0001764 22 0.023
negative regulation of ras protein signal transduction GO:0046580 1 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
lipid homeostasis GO:0055088 3 0.023
wnt signaling pathway GO:0016055 80 0.023
mitotic cell cycle GO:0000278 64 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.022
hypothalamus cell differentiation GO:0021979 4 0.022
regulation of transferase activity GO:0051338 16 0.022
Human Mouse Fly
cellular response to stress GO:0033554 62 0.022
Human Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
female sex differentiation GO:0046660 4 0.022
hemopoiesis GO:0030097 183 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
Human Mouse Fly
protein targeting to nucleus GO:0044744 3 0.021
regulation of cellular component organization GO:0051128 86 0.021
Fly
microtubule cytoskeleton organization GO:0000226 33 0.021
regulation of protein catabolic process GO:0042176 1 0.021
positive regulation of multicellular organismal process GO:0051240 52 0.021
lipid storage GO:0019915 1 0.021
response to stress GO:0006950 263 0.021
Human Mouse Fly
establishment of organelle localization GO:0051656 45 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
homeostatic process GO:0042592 142 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
organic acid metabolic process GO:0006082 31 0.020
ras protein signal transduction GO:0007265 7 0.020
immune system process GO:0002376 241 0.020
Fly
segmentation GO:0035282 97 0.020
neurotransmitter secretion GO:0007269 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
lamellipodium organization GO:0097581 1 0.020
regulation of wnt signaling pathway GO:0030111 53 0.019
cell proliferation GO:0008283 80 0.019
anatomical structure arrangement GO:0048532 2 0.019
organic substance transport GO:0071702 58 0.019
vascular endothelial growth factor signaling pathway GO:0038084 3 0.019
lamellipodium assembly GO:0030032 1 0.019
pancreas development GO:0031016 84 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
cellular response to starvation GO:0009267 1 0.019
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
negative regulation of protein complex assembly GO:0031333 1 0.018
gland development GO:0048732 143 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
Fly
meiotic nuclear division GO:0007126 4 0.017
gtp catabolic process GO:0006184 2 0.017
negative regulation of neuron projection regeneration GO:0070571 4 0.017
mapk cascade GO:0000165 18 0.017
Human Mouse Fly
digestive tract development GO:0048565 265 0.017
carbohydrate homeostasis GO:0033500 1 0.017
homeostasis of number of cells GO:0048872 62 0.017
circadian sleep wake cycle sleep GO:0050802 1 0.017
central nervous system development GO:0007417 387 0.017
regulation of proteolysis GO:0030162 24 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
establishment or maintenance of cell polarity GO:0007163 29 0.017
response to ketone GO:1901654 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
metencephalon development GO:0022037 27 0.016
regulation of glucose transport GO:0010827 1 0.016
negative regulation of translation GO:0017148 1 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
convergent extension involved in gastrulation GO:0060027 71 0.016
cell growth GO:0016049 57 0.016
rna 3 end processing GO:0031123 2 0.016
cellular component disassembly GO:0022411 1 0.016
dna templated transcription elongation GO:0006354 3 0.016
cell cycle process GO:0022402 53 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
chromosome organization GO:0051276 31 0.015
Fly
establishment of apical basal cell polarity GO:0035089 2 0.015
microtubule based movement GO:0007018 33 0.015
embryonic skeletal joint development GO:0072498 3 0.015
response to abiotic stimulus GO:0009628 122 0.015
Human Fly
positive regulation of developmental process GO:0051094 50 0.015
positive regulation of jun kinase activity GO:0043507 2 0.015
Human Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.015
female gonad development GO:0008585 4 0.015
regulation of protein polymerization GO:0032271 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.015
regulation of cell morphogenesis GO:0022604 42 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
catabolic process GO:0009056 32 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
protein polymerization GO:0051258 4 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.014
regulation of protein complex assembly GO:0043254 3 0.014
rna localization GO:0006403 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
establishment of mitotic spindle localization GO:0040001 12 0.014
autophagy GO:0006914 4 0.014
regulation of smoothened signaling pathway GO:0008589 18 0.014
negative regulation of dna recombination GO:0045910 2 0.014
chemotaxis GO:0006935 104 0.014
dna biosynthetic process GO:0071897 3 0.014
spermatid differentiation GO:0048515 2 0.014
metal ion transport GO:0030001 58 0.014
regulation of response to stress GO:0080134 36 0.014
Human Mouse Fly
tissue remodeling GO:0048771 4 0.014
cellular response to oxygen containing compound GO:1901701 20 0.014
anterior posterior pattern specification GO:0009952 152 0.013
polarized epithelial cell differentiation GO:0030859 4 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
negative regulation of metabolic process GO:0009892 86 0.013
Fly
negative regulation of catabolic process GO:0009895 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
Fly
embryonic organ morphogenesis GO:0048562 274 0.013
response to hormone GO:0009725 48 0.013
regulation of cell projection organization GO:0031344 44 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
Human Mouse Fly
vasculature development GO:0001944 278 0.013
regulation of programmed cell death GO:0043067 101 0.012
regulation of phosphorylation GO:0042325 26 0.012
Human Mouse Fly
negative regulation of intracellular transport GO:0032387 3 0.012
sympathetic ganglion development GO:0061549 2 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
synaptic target recognition GO:0008039 1 0.012
regulation of kinase activity GO:0043549 15 0.012
Human Mouse Fly
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.012
smoothened signaling pathway GO:0007224 30 0.012
negative regulation of defense response GO:0031348 2 0.012
cellular macromolecule localization GO:0070727 21 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
response to endogenous stimulus GO:0009719 83 0.012
reproduction GO:0000003 40 0.012
cardiac cell fate commitment GO:0060911 1 0.012
mitochondrion organization GO:0007005 4 0.012
oogenesis GO:0048477 14 0.012
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.012
negative regulation of cellular component organization GO:0051129 16 0.012
Fly
neuron development GO:0048666 262 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of cell motility GO:2000145 46 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
viral process GO:0016032 1 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
muscle cell differentiation GO:0042692 139 0.011
lipid metabolic process GO:0006629 52 0.011
protein complex disassembly GO:0043241 1 0.011
regulation of mrna processing GO:0050684 3 0.011
regulation of protein phosphorylation GO:0001932 18 0.011
Human Mouse Fly
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
mrna 3 end processing GO:0031124 2 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
positive regulation of phosphate metabolic process GO:0045937 21 0.011
Human Mouse Fly
single organism reproductive process GO:0044702 40 0.011
Mouse
regulation of cytokine production GO:0001817 3 0.011
multicellular organism reproduction GO:0032504 35 0.011
dsrna fragmentation GO:0031050 1 0.011
regulation of translational initiation GO:0006446 1 0.011
meiosis i GO:0007127 1 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
cilium morphogenesis GO:0060271 85 0.011
angiogenesis GO:0001525 158 0.011
cellular response to external stimulus GO:0071496 2 0.011
cell recognition GO:0008037 19 0.011
germ line stem cell division GO:0042078 1 0.011
regulation of system process GO:0044057 40 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of phosphorus metabolic process GO:0010562 21 0.010
Human Mouse Fly
synaptic vesicle transport GO:0048489 1 0.010
positive regulation of intracellular signal transduction GO:1902533 15 0.010
Human Mouse Fly
proteasomal protein catabolic process GO:0010498 2 0.010
macromolecule localization GO:0033036 54 0.010
regulation of gtpase activity GO:0043087 2 0.010
rna processing GO:0006396 25 0.010
neural tube development GO:0021915 62 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
neural precursor cell proliferation GO:0061351 20 0.010
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.010
heart contraction GO:0060047 71 0.010
embryonic pattern specification GO:0009880 44 0.010
embryonic organ development GO:0048568 381 0.010
larval heart development GO:0007508 2 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
reproductive process GO:0022414 40 0.010
Mouse
positive regulation of cell adhesion GO:0045785 1 0.010
protein complex subunit organization GO:0071822 46 0.010
specification of symmetry GO:0009799 204 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
Fly
neuron projection regeneration GO:0031102 16 0.010
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
regulation of anatomical structure size GO:0090066 33 0.010
Fly
establishment of mitotic spindle orientation GO:0000132 10 0.010
cell aging GO:0007569 2 0.010
pons development GO:0021548 11 0.010

map3k4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.014
brain disease DOID:936 0 0.011
epilepsy syndrome DOID:1826 0 0.011
central nervous system disease DOID:331 0 0.011