Danio rerio

18 known processes

mapk1

mitogen-activated protein kinase 1

(Aliases: zERK2)

mapk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptidyl serine phosphorylation GO:0018105 1 0.987
Human Mouse Rat Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.920
Yeast Rat
gene expression GO:0010467 252 0.909
Yeast Rat
regulation of macromolecule metabolic process GO:0060255 317 0.900
Human Yeast Rat
cellular biosynthetic process GO:0044249 286 0.878
Yeast Rat
regulation of biosynthetic process GO:0009889 250 0.865
Yeast Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.848
Yeast Rat
regulation of gene expression GO:0010468 265 0.847
Yeast Rat
regulation of macromolecule biosynthetic process GO:0010556 225 0.801
Yeast Rat
regulation of metabolic process GO:0019222 359 0.801
Human Yeast Rat Fly
regulation of transcription dna templated GO:0006355 213 0.793
Yeast Rat
response to oxidative stress GO:0006979 11 0.773
Fly
larval development GO:0002164 2 0.759
Worm
chordate embryonic development GO:0043009 271 0.723
Zebrafish Mouse
adherens junction organization GO:0034332 4 0.719
Fly
digestive system development GO:0055123 289 0.714
digestive tract morphogenesis GO:0048546 231 0.713
regulation of response to stimulus GO:0048583 269 0.712
Yeast Mouse Fly
signal transduction GO:0007165 455 0.705
Human Yeast Mouse Rat Worm Fly
heterocycle biosynthetic process GO:0018130 215 0.698
Yeast Rat
nucleic acid templated transcription GO:0097659 181 0.697
Yeast Rat
nucleobase containing compound metabolic process GO:0006139 274 0.696
Yeast Mouse Rat
nucleic acid metabolic process GO:0090304 244 0.693
Yeast Rat
cell migration GO:0016477 237 0.686
Rat
nucleocytoplasmic transport GO:0006913 4 0.680
Yeast Rat
single organism transport GO:0044765 206 0.677
Yeast Rat
regulation of cellular biosynthetic process GO:0031326 245 0.677
Yeast Rat
cell motility GO:0048870 244 0.647
Rat
head development GO:0060322 303 0.626
Zebrafish
ameboidal type cell migration GO:0001667 143 0.615
cellular macromolecule metabolic process GO:0044260 391 0.612
Human Yeast Mouse Rat Worm Fly
mesodermal cell migration GO:0008078 12 0.607
gastrulation GO:0007369 208 0.591
organic cyclic compound biosynthetic process GO:1901362 223 0.591
Yeast Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.589
Yeast Rat
positive regulation of gene expression GO:0010628 71 0.588
Rat
cell migration involved in gastrulation GO:0042074 79 0.575
regulation of meiotic cell cycle GO:0051445 1 0.575
Worm
macromolecule biosynthetic process GO:0009059 227 0.571
Yeast Rat
tube morphogenesis GO:0035239 349 0.558
determination of left right symmetry GO:0007368 179 0.548
determination of bilateral symmetry GO:0009855 204 0.546
homeostatic process GO:0042592 142 0.537
positive regulation of rna metabolic process GO:0051254 59 0.527
Rat
regulation of primary metabolic process GO:0080090 311 0.522
Human Yeast Rat
embryonic heart tube development GO:0035050 133 0.512
adherens junction maintenance GO:0034334 2 0.511
Fly
rna metabolic process GO:0016070 219 0.506
Yeast Rat
response to drug GO:0042493 3 0.505
Fly
aging GO:0007568 2 0.505
Worm
regulation of rna metabolic process GO:0051252 224 0.504
Yeast Rat
cellular component maintenance GO:0043954 3 0.502
Fly
convergent extension involved in gastrulation GO:0060027 71 0.499
central nervous system neuron axonogenesis GO:0021955 18 0.495
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.483
Yeast Rat
organic substance biosynthetic process GO:1901576 289 0.482
Yeast Rat
digestive tract development GO:0048565 265 0.474
regulation of rna biosynthetic process GO:2001141 213 0.473
Yeast Rat
localization of cell GO:0051674 244 0.452
Rat
positive regulation of metabolic process GO:0009893 108 0.450
Human Rat Fly
eye development GO:0001654 277 0.447
Zebrafish
transcription dna templated GO:0006351 181 0.445
Yeast Rat
nuclear transport GO:0051169 4 0.434
Yeast Rat
blood vessel development GO:0001568 246 0.430
Mouse
response to abiotic stimulus GO:0009628 122 0.414
response to other organism GO:0051707 97 0.412
Mouse
rna biosynthetic process GO:0032774 181 0.409
Yeast Rat
vasculature development GO:0001944 278 0.406
Mouse
regulation of protein binding GO:0043393 3 0.402
regulation of synapse assembly GO:0051963 3 0.400
nitrogen compound metabolic process GO:0006807 319 0.398
Yeast Mouse Rat
regulation of transport GO:0051049 45 0.393
Yeast
positive regulation of cellular metabolic process GO:0031325 94 0.392
Human Rat Fly
positive regulation of biological process GO:0048518 253 0.391
Human Yeast Mouse Rat Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.390
Worm Fly
multicellular organism growth GO:0035264 4 0.387
regulation of establishment of protein localization GO:0070201 4 0.377
Yeast
regulation of multicellular organismal development GO:2000026 223 0.376
Worm Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.375
Fly
ion homeostasis GO:0050801 41 0.375
nucleobase containing compound biosynthetic process GO:0034654 205 0.374
Yeast Rat
determination of heart left right asymmetry GO:0061371 117 0.371
cell surface receptor signaling pathway GO:0007166 325 0.370
Human Yeast Mouse Fly
biosynthetic process GO:0009058 294 0.369
Yeast Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.366
Yeast Rat
single organism metabolic process GO:0044710 217 0.365
Human Yeast Mouse Rat Worm Fly
phosphate containing compound metabolic process GO:0006796 108 0.360
Human Yeast Mouse Rat Worm Fly
neuron development GO:0048666 262 0.359
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.357
regulation of cellular metabolic process GO:0031323 320 0.354
Human Yeast Rat Fly
heart development GO:0007507 313 0.353
positive regulation of multicellular organismal process GO:0051240 52 0.352
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.348
Zebrafish
hemopoiesis GO:0030097 183 0.347
phosphorylation GO:0016310 69 0.345
Human Yeast Mouse Rat Worm Fly
nuclear export GO:0051168 1 0.344
Yeast
regulation of nucleic acid templated transcription GO:1903506 213 0.344
Yeast Rat
regulation of dna replication GO:0006275 3 0.340
heart morphogenesis GO:0003007 156 0.338
regulation of protein transport GO:0051223 3 0.337
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.336
Yeast Mouse Rat
specification of symmetry GO:0009799 204 0.326
regulation of vesicle mediated transport GO:0060627 9 0.323
response to organic substance GO:0010033 153 0.321
Human Yeast Mouse Rat Fly
regulation of dna templated transcription in response to stress GO:0043620 0 0.321
cellular component movement GO:0006928 335 0.320
Rat
regulation of signal transduction GO:0009966 225 0.318
Yeast Fly
establishment of localization GO:0051234 244 0.314
Yeast Rat
cell junction organization GO:0034330 11 0.304
Fly
regulation of developmental process GO:0050793 247 0.304
Mouse Worm Fly
negative regulation of autophagy GO:0010507 1 0.304
Fly
aromatic compound biosynthetic process GO:0019438 217 0.297
Yeast Rat
neural tube development GO:0021915 62 0.295
establishment of protein localization to organelle GO:0072594 4 0.294
Rat
locomotion GO:0040011 313 0.292
Rat
negative regulation of response to stimulus GO:0048585 104 0.291
Yeast Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.291
Yeast Mouse Rat
single organism localization GO:1902578 225 0.286
Yeast Rat
peptidyl serine modification GO:0018209 2 0.284
Human Mouse Rat Worm
central nervous system projection neuron axonogenesis GO:0021952 15 0.283
Zebrafish
wnt signaling pathway GO:0016055 80 0.279
response to biotic stimulus GO:0009607 97 0.270
Mouse
locomotor rhythm GO:0045475 3 0.270
negative regulation of cellular process GO:0048523 283 0.269
Yeast Mouse Worm Fly
histone phosphorylation GO:0016572 2 0.259
cellular localization GO:0051641 97 0.253
Yeast Rat
regulation of cell communication GO:0010646 232 0.253
Yeast Fly
epithelial tube morphogenesis GO:0060562 148 0.251
protein phosphorylation GO:0006468 47 0.250
Human Yeast Mouse Rat Worm Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.248
positive regulation of cellular process GO:0048522 201 0.248
Human Rat Worm Fly
regulation of synapse organization GO:0050807 3 0.246
protein import GO:0017038 3 0.244
Rat
negative regulation of signal transduction GO:0009968 94 0.243
Yeast
negative regulation of multicellular organismal process GO:0051241 69 0.241
Worm
positive regulation of transport GO:0051050 2 0.240
Yeast
embryonic heart tube morphogenesis GO:0003143 108 0.239
hematopoietic or lymphoid organ development GO:0048534 191 0.237
response to reactive oxygen species GO:0000302 5 0.236
Fly
regulation of signaling GO:0023051 235 0.235
Yeast Fly
negative regulation of biological process GO:0048519 304 0.235
Yeast Mouse Worm Fly
sensory organ morphogenesis GO:0090596 200 0.230
peptidyl threonine phosphorylation GO:0018107 1 0.227
Human Mouse
regulation of cell motility GO:2000145 46 0.226
Rat
protein targeting to nucleus GO:0044744 3 0.226
Rat
regulation of binding GO:0051098 3 0.226
positive regulation of nucleic acid templated transcription GO:1903508 57 0.224
Rat
organic substance transport GO:0071702 58 0.217
Yeast Rat
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.217
Rat
multi organism process GO:0051704 134 0.216
Yeast Mouse Worm
convergent extension GO:0060026 118 0.213
enzyme linked receptor protein signaling pathway GO:0007167 106 0.212
Human Fly
central nervous system development GO:0007417 387 0.205
Zebrafish
heterocycle metabolic process GO:0046483 290 0.201
Yeast Mouse Rat
response to endogenous stimulus GO:0009719 83 0.197
Human Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.195
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.194
Human Rat
transcription from rna polymerase ii promoter GO:0006366 80 0.192
regulation of localization GO:0032879 104 0.192
Yeast Rat
cellular component assembly GO:0022607 170 0.188
regulation of anatomical structure morphogenesis GO:0022603 130 0.183
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.183
response to stress GO:0006950 263 0.181
Mouse Worm Fly
regulation of metal ion transport GO:0010959 4 0.180
metal ion transport GO:0030001 58 0.178
cellular response to lipopolysaccharide GO:0071222 3 0.173
Mouse
morphogenesis of an epithelium GO:0002009 333 0.173
bmp signaling pathway GO:0030509 52 0.172
cell junction maintenance GO:0034331 2 0.170
Fly
regulation of receptor mediated endocytosis GO:0048259 4 0.169
anterior posterior pattern specification GO:0009952 152 0.169
regulation of wound healing GO:0061041 2 0.169
Fly
angiogenesis GO:0001525 158 0.169
maintenance of location GO:0051235 4 0.168
signal transduction by phosphorylation GO:0023014 18 0.168
Human Yeast Mouse Rat Worm Fly
type b pancreatic cell proliferation GO:0044342 1 0.163
regulation of protein complex assembly GO:0043254 3 0.163
stem cell maintenance GO:0019827 4 0.161
synaptic growth at neuromuscular junction GO:0051124 2 0.161
nuclear migration GO:0007097 3 0.160
regulation of cytoplasmic transport GO:1903649 4 0.160
Yeast
positive regulation of cell communication GO:0010647 56 0.156
Fly
dorsal convergence GO:0060030 14 0.155
cell projection organization GO:0030030 284 0.153
Zebrafish
defense response GO:0006952 47 0.151
regulation of nervous system development GO:0051960 90 0.151
Fly
positive regulation of developmental process GO:0051094 50 0.150
Fly
cell substrate adhesion GO:0031589 4 0.149
cellular aromatic compound metabolic process GO:0006725 295 0.148
Yeast Mouse Rat
positive regulation of biosynthetic process GO:0009891 68 0.148
Rat
single organism organelle organization GO:1902589 199 0.147
Fly
response to nitrogen compound GO:1901698 19 0.146
Mouse
regulation of biological quality GO:0065008 263 0.144
organelle localization GO:0051640 49 0.144
negative regulation of cellular biosynthetic process GO:0031327 55 0.142
cellular component biogenesis GO:0044085 178 0.141
oocyte maturation GO:0001556 4 0.140
Worm
regulation of intracellular signal transduction GO:1902531 57 0.139
Yeast Fly
regulation of multicellular organism growth GO:0040014 4 0.138
regulation of bmp signaling pathway GO:0030510 39 0.137
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.135
autophagy GO:0006914 4 0.133
Fly
oxoacid metabolic process GO:0043436 31 0.131
cell cycle process GO:0022402 53 0.130
Yeast Worm Fly
transport GO:0006810 220 0.129
Yeast Rat
cation transport GO:0006812 81 0.128
meiotic nuclear division GO:0007126 4 0.127
establishment of localization in cell GO:0051649 77 0.124
Yeast Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.123
negative regulation of wnt signaling pathway GO:0030178 30 0.122
cellular carbohydrate metabolic process GO:0044262 4 0.122
intracellular signal transduction GO:0035556 85 0.122
Human Yeast Mouse Rat Worm Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.121
Rat
regulation of reproductive process GO:2000241 4 0.121
positive regulation of cellular amine metabolic process GO:0033240 0 0.121
negative regulation of cell communication GO:0010648 96 0.121
Yeast Fly
protein modification process GO:0036211 100 0.120
Human Yeast Mouse Rat Worm Fly
protein localization to nucleus GO:0034504 3 0.120
Rat
chemical homeostasis GO:0048878 49 0.119
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.119
positive regulation of striated muscle tissue development GO:0045844 1 0.118
nucleoside phosphate biosynthetic process GO:1901293 21 0.117
immune response GO:0006955 28 0.117
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.116
Rat
cellular amine metabolic process GO:0044106 2 0.116
response to organic cyclic compound GO:0014070 51 0.114
Mouse Rat
positive regulation of response to stimulus GO:0048584 80 0.114
Mouse Fly
negative regulation of mapk cascade GO:0043409 4 0.114
Yeast
positive regulation of secretion by cell GO:1903532 1 0.114
lipid storage GO:0019915 1 0.114
cytoskeleton organization GO:0007010 96 0.113
negative regulation of signaling GO:0023057 96 0.112
Yeast
long chain fatty acid metabolic process GO:0001676 1 0.111
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.111
immune system process GO:0002376 241 0.110
Mouse
positive regulation of cell cycle GO:0045787 3 0.109
Worm
regulation of phosphorus metabolic process GO:0051174 43 0.108
Human Yeast Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.108
peptidyl threonine modification GO:0018210 1 0.108
Human Mouse
protein metabolic process GO:0019538 183 0.107
Human Yeast Mouse Rat Worm Fly
negative regulation of synapse assembly GO:0051964 2 0.107
regulation of nucleocytoplasmic transport GO:0046822 2 0.106
Yeast
cell adhesion GO:0007155 40 0.106
cellular response to growth factor stimulus GO:0071363 39 0.105
sensory organ development GO:0007423 393 0.104
Zebrafish
phagocytosis GO:0006909 3 0.104
liver development GO:0001889 96 0.103
glucose import GO:0046323 2 0.103
cellular response to stress GO:0033554 62 0.102
Mouse Fly
positive regulation of cell adhesion GO:0045785 1 0.100
ion transport GO:0006811 114 0.098
heart looping GO:0001947 94 0.098
brain development GO:0007420 293 0.098
Zebrafish
calcium ion transport GO:0006816 18 0.097
mesoderm development GO:0007498 88 0.097
organophosphate biosynthetic process GO:0090407 23 0.097
protein import into nucleus GO:0006606 3 0.097
Rat
regulation of organ morphogenesis GO:2000027 35 0.097
regionalization GO:0003002 274 0.096
Fly
growth GO:0040007 174 0.096
Yeast
g protein coupled receptor signaling pathway GO:0007186 74 0.096
Yeast
negative regulation of protein kinase activity GO:0006469 4 0.096
response to chemical GO:0042221 320 0.096
Human Yeast Mouse Rat Fly
cell cycle arrest GO:0007050 1 0.095
Yeast
carboxylic acid metabolic process GO:0019752 22 0.094
positive regulation of histone modification GO:0031058 1 0.093
regulation of erk1 and erk2 cascade GO:0070372 4 0.092
Fly
cell fate specification GO:0001708 68 0.092
regulation of cell differentiation GO:0045595 142 0.090
Mouse Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.090
biological adhesion GO:0022610 40 0.089
regulation of cellular amine metabolic process GO:0033238 0 0.089
cellular protein modification process GO:0006464 100 0.089
Human Yeast Mouse Rat Worm Fly
response to lipid GO:0033993 60 0.088
Mouse Rat
response to glucocorticoid GO:0051384 1 0.088
regulation of growth GO:0040008 42 0.088
regulation of response to nutrient levels GO:0032107 1 0.088
Fly
regulation of protein localization to nucleus GO:1900180 2 0.086
cellular response to chemical stimulus GO:0070887 157 0.086
Yeast Mouse Rat Fly
regulation of autophagy GO:0010506 3 0.085
Fly
regulation of cellular component organization GO:0051128 86 0.084
multi organism reproductive process GO:0044703 36 0.084
Yeast Worm
blood vessel morphogenesis GO:0048514 216 0.084
cellular response to oxidative stress GO:0034599 5 0.083
Fly
intracellular transport GO:0046907 32 0.083
Yeast Rat
death GO:0016265 121 0.082
Worm
negative regulation of biosynthetic process GO:0009890 55 0.082
regulation of dendrite development GO:0050773 3 0.082
regulation of intracellular protein transport GO:0033157 3 0.082
Yeast
embryonic organ development GO:0048568 381 0.080
Mouse
positive regulation of muscle cell differentiation GO:0051149 1 0.080
forebrain development GO:0030900 96 0.079
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.079
positive regulation of signaling GO:0023056 56 0.078
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.078
neurological system process GO:0050877 62 0.078
Rat
regulation of response to oxidative stress GO:1902882 2 0.077
cellular response to biotic stimulus GO:0071216 3 0.077
Mouse
regulation of protein polymerization GO:0032271 2 0.076
olfactory lobe development GO:0021988 4 0.076
single organism nuclear import GO:1902593 3 0.076
Rat
immune system development GO:0002520 191 0.075
positive regulation of muscle organ development GO:0048636 1 0.075
regulation of protein phosphorylation GO:0001932 18 0.074
Human
negative regulation of protein kinase b signaling GO:0051898 2 0.074
regulation of mrna processing GO:0050684 3 0.074
single organism cellular localization GO:1902580 46 0.073
Rat
regulation of wnt signaling pathway GO:0030111 53 0.073
photoreceptor cell differentiation GO:0046530 55 0.073
Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.073
Yeast
ras protein signal transduction GO:0007265 7 0.072
Worm Fly
negative regulation of catabolic process GO:0009895 3 0.072
Fly
limbic system development GO:0021761 16 0.072
regulation of cell substrate adhesion GO:0010810 1 0.071
cell cycle GO:0007049 93 0.071
Yeast Worm Fly
cellular ketone metabolic process GO:0042180 11 0.070
response to external stimulus GO:0009605 264 0.070
Mouse Fly
sensory perception GO:0007600 39 0.070
Rat
response to wounding GO:0009611 116 0.069
Fly
single organism biosynthetic process GO:0044711 71 0.068
cell substrate adherens junction assembly GO:0007045 1 0.068
positive regulation of muscle tissue development GO:1901863 1 0.068
negative regulation of protein phosphorylation GO:0001933 4 0.068
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.067
axonogenesis GO:0007409 152 0.067
Zebrafish
regulation of canonical wnt signaling pathway GO:0060828 34 0.067
cell cell signaling GO:0007267 52 0.067
Fly
regulation of protein metabolic process GO:0051246 56 0.066
Human Rat
nuclear import GO:0051170 3 0.066
Rat
regulation of endocytosis GO:0030100 7 0.066
eye morphogenesis GO:0048592 144 0.066
single organism intracellular transport GO:1902582 25 0.066
Yeast Rat
regulation of developmental growth GO:0048638 38 0.066
negative regulation of metabolic process GO:0009892 86 0.066
Yeast Fly
cell morphogenesis GO:0000902 289 0.065
Zebrafish
regulation of glucose transport GO:0010827 1 0.065
generation of neurons GO:0048699 385 0.065
Zebrafish Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.065
Human Fly
positive regulation of cell differentiation GO:0045597 30 0.064
Fly
organelle assembly GO:0070925 110 0.064
cellular lipid metabolic process GO:0044255 36 0.064
behavior GO:0007610 74 0.063
Fly
cell cell junction organization GO:0045216 10 0.063
Fly
regulation of ion transport GO:0043269 22 0.063
metal ion homeostasis GO:0055065 26 0.062
cellular response to external stimulus GO:0071496 2 0.062
Fly
actin polymerization or depolymerization GO:0008154 2 0.062
maternal determination of anterior posterior axis embryo GO:0008358 4 0.061
cartilage development GO:0051216 96 0.061
positive regulation of translation GO:0045727 1 0.061
Rat
nucleus localization GO:0051647 8 0.061
cellular protein metabolic process GO:0044267 129 0.061
Human Yeast Mouse Rat Worm Fly
sphingolipid biosynthetic process GO:0030148 2 0.061
protein secretion GO:0009306 1 0.061
response to metal ion GO:0010038 34 0.060
Fly
renal system development GO:0072001 94 0.060
regulation of establishment of planar polarity GO:0090175 4 0.060
positive regulation of oocyte development GO:0060282 1 0.060
regulation of response to external stimulus GO:0032101 31 0.059
Fly
connective tissue development GO:0061448 99 0.059
apical junction assembly GO:0043297 1 0.058
camera type eye development GO:0043010 222 0.058
positive regulation of chromosome organization GO:2001252 1 0.057
synapse organization GO:0050808 21 0.057
synapse assembly GO:0007416 9 0.057
regulation of neuron differentiation GO:0045664 56 0.056
Fly
convergent extension involved in axis elongation GO:0060028 26 0.056
rhythmic process GO:0048511 21 0.056
cellular response to organic substance GO:0071310 105 0.056
Yeast Mouse Rat
response to oxygen containing compound GO:1901700 55 0.056
Mouse Fly
cellular amino acid metabolic process GO:0006520 7 0.056
regulation of synaptic plasticity GO:0048167 1 0.056
skeletal system development GO:0001501 181 0.055
response to external biotic stimulus GO:0043207 97 0.055
Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.055
cortical cytoskeleton organization GO:0030865 1 0.055
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.055
positive regulation of striated muscle cell differentiation GO:0051155 1 0.054
phosphorus metabolic process GO:0006793 109 0.054
Human Yeast Mouse Rat Worm Fly
neuroblast proliferation GO:0007405 2 0.054
cellular response to molecule of bacterial origin GO:0071219 3 0.053
Mouse
response to mechanical stimulus GO:0009612 24 0.053
cellular response to oxygen containing compound GO:1901701 20 0.053
Mouse Fly
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.052
response to growth factor GO:0070848 39 0.052
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.052
olfactory bulb development GO:0021772 4 0.052
determination of dorsal ventral asymmetry GO:0048262 34 0.052
carbohydrate homeostasis GO:0033500 1 0.052
regulation of cellular ketone metabolic process GO:0010565 7 0.052
cellular response to starvation GO:0009267 1 0.052
Fly
regulation of cell cycle GO:0051726 52 0.052
Yeast Worm
positive regulation of cellular biosynthetic process GO:0031328 68 0.051
Rat
negative regulation of dna replication GO:0008156 2 0.051
rna processing GO:0006396 25 0.051
positive regulation of dna metabolic process GO:0051054 1 0.051
regulation of heart contraction GO:0008016 32 0.051
regulation of calcium ion transport GO:0051924 2 0.051
positive regulation of signal transduction GO:0009967 56 0.051
Fly
membrane lipid biosynthetic process GO:0046467 2 0.051
cell substrate junction assembly GO:0007044 2 0.051
circadian rhythm GO:0007623 19 0.051
pancreas development GO:0031016 84 0.051
negative regulation of apoptotic process GO:0043066 55 0.050
cellular response to decreased oxygen levels GO:0036294 1 0.050
negative regulation of cell differentiation GO:0045596 46 0.049
Mouse
urogenital system development GO:0001655 97 0.048
regulation of neurological system process GO:0031644 2 0.048
neuron differentiation GO:0030182 353 0.048
Zebrafish Fly
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.048
Fly
divalent inorganic cation homeostasis GO:0072507 22 0.048
regulation of immune system process GO:0002682 34 0.048
Mouse
regulation of oocyte development GO:0060281 3 0.048
embryo development ending in birth or egg hatching GO:0009792 271 0.048
Zebrafish Mouse Worm
organic acid metabolic process GO:0006082 31 0.047
regulation of sodium ion transport GO:0002028 2 0.047
negative regulation of dna metabolic process GO:0051053 4 0.047
protein autophosphorylation GO:0046777 5 0.047
Yeast
oocyte anterior posterior axis specification GO:0007314 4 0.047
specification of axis polarity GO:0065001 4 0.047
extrinsic apoptotic signaling pathway GO:0097191 3 0.046
microtubule cytoskeleton organization GO:0000226 33 0.046
endocytosis GO:0006897 16 0.046
positive regulation of exocytosis GO:0045921 1 0.046
gastrulation with mouth forming second GO:0001702 44 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.045
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.045
posttranscriptional regulation of gene expression GO:0010608 14 0.045
Rat
canonical wnt signaling pathway GO:0060070 48 0.045
regulation of epithelial cell proliferation GO:0050678 3 0.045
somite development GO:0061053 96 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.045
negative regulation of epithelial cell proliferation GO:0050680 1 0.045
negative regulation of cellular metabolic process GO:0031324 77 0.045
Yeast Fly
cellular component morphogenesis GO:0032989 336 0.044
Zebrafish
striated muscle tissue development GO:0014706 110 0.044
cellular response to hypoxia GO:0071456 1 0.044
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.044
vesicle localization GO:0051648 27 0.044
ceramide biosynthetic process GO:0046513 1 0.044
epithelial cell migration GO:0010631 25 0.044
positive regulation of secretion GO:0051047 1 0.043
hormone transport GO:0009914 2 0.043
positive regulation of synapse assembly GO:0051965 1 0.043
glucose homeostasis GO:0042593 1 0.043
response to bacterium GO:0009617 58 0.043
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.043
Rat
phagocytosis engulfment GO:0006911 1 0.043
locomotory behavior GO:0007626 34 0.043
positive regulation of nervous system development GO:0051962 25 0.042
Fly
internal protein amino acid acetylation GO:0006475 2 0.042
meiotic cell cycle process GO:1903046 3 0.042
amine metabolic process GO:0009308 2 0.042
circadian sleep wake cycle GO:0042745 2 0.042
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.042
nucleotide biosynthetic process GO:0009165 21 0.042
cation homeostasis GO:0055080 33 0.041
cellular macromolecular complex assembly GO:0034622 24 0.041
negative regulation of translation GO:0017148 1 0.041
negative regulation of programmed cell death GO:0043069 58 0.040
ear development GO:0043583 127 0.040
cellular response to reactive oxygen species GO:0034614 2 0.040
Fly
muscle structure development GO:0061061 196 0.040
developmental growth GO:0048589 166 0.040
adult behavior GO:0030534 2 0.040
Fly
negative regulation of map kinase activity GO:0043407 2 0.040
mitotic nuclear division GO:0007067 18 0.040
Fly
germ line stem cell maintenance GO:0030718 2 0.040
reactive oxygen species metabolic process GO:0072593 6 0.039
synaptic transmission GO:0007268 35 0.039
Fly
sexual reproduction GO:0019953 36 0.039
Yeast Worm
cognition GO:0050890 1 0.039
response to fluid shear stress GO:0034405 2 0.039
renal tubule morphogenesis GO:0061333 1 0.039
positive regulation of transcription dna templated GO:0045893 57 0.039
Rat
forebrain cell migration GO:0021885 1 0.039
kidney development GO:0001822 92 0.039
regulation of cellular component movement GO:0051270 55 0.039
Rat
translation GO:0006412 5 0.039
Rat
stem cell proliferation GO:0072089 4 0.039
regulation of reactive oxygen species metabolic process GO:2000377 2 0.038
cellular response to endogenous stimulus GO:0071495 68 0.038
actin filament polymerization GO:0030041 2 0.038
regulation of response to stress GO:0080134 36 0.038
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.037
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.037
optic placode formation GO:0001743 4 0.037
cytoplasmic transport GO:0016482 11 0.037
Yeast Rat
reactive oxygen species biosynthetic process GO:1903409 1 0.037
cell aging GO:0007569 2 0.037
synaptic vesicle localization GO:0097479 1 0.036
regulation of cellular response to oxidative stress GO:1900407 2 0.036
positive regulation of chromatin modification GO:1903310 1 0.036
cell proliferation GO:0008283 80 0.036
Mouse Rat Fly
negative regulation of cell migration GO:0030336 17 0.036
response to dsrna GO:0043331 7 0.036
Mouse
cell part morphogenesis GO:0032990 246 0.036
Zebrafish
central nervous system neuron development GO:0021954 29 0.036
Zebrafish

mapk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.172