Danio rerio

0 known processes

mapk6

mitogen-activated protein kinase 6

(Aliases: erk3,si:ch211-235f12.1,p97mapk)

mapk6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptidyl serine modification GO:0018209 2 0.530
extrinsic apoptotic signaling pathway GO:0097191 3 0.495
protein localization to nucleus GO:0034504 3 0.474
cellular macromolecule metabolic process GO:0044260 391 0.428
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.387
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.367
digestive tract morphogenesis GO:0048546 231 0.363
protein import into nucleus GO:0006606 3 0.355
signal transduction GO:0007165 455 0.330
Mouse
gastrulation GO:0007369 208 0.318
peptidyl serine phosphorylation GO:0018105 1 0.311
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.305
head development GO:0060322 303 0.304
regulation of primary metabolic process GO:0080090 311 0.290
cell fate commitment GO:0045165 99 0.278
nuclear transport GO:0051169 4 0.277
positive regulation of cellular process GO:0048522 201 0.272
regulation of protein localization to nucleus GO:1900180 2 0.263
transcription dna templated GO:0006351 181 0.260
tube morphogenesis GO:0035239 349 0.252
regulation of dna templated transcription in response to stress GO:0043620 0 0.252
protein modification process GO:0036211 100 0.250
Mouse
sequestering of calcium ion GO:0051208 3 0.241
cellular biosynthetic process GO:0044249 286 0.240
regulation of cellular metabolic process GO:0031323 320 0.235
phosphate containing compound metabolic process GO:0006796 108 0.234
Mouse
regulation of protein transport GO:0051223 3 0.231
nitrogen compound metabolic process GO:0006807 319 0.231
regulation of dna replication GO:0006275 3 0.224
regulation of nitrogen compound metabolic process GO:0051171 251 0.224
single organism metabolic process GO:0044710 217 0.216
Mouse
regulation of biosynthetic process GO:0009889 250 0.215
nucleic acid metabolic process GO:0090304 244 0.200
digestive system development GO:0055123 289 0.197
aromatic compound biosynthetic process GO:0019438 217 0.190
digestive tract development GO:0048565 265 0.189
organic cyclic compound biosynthetic process GO:1901362 223 0.189
cell migration involved in gastrulation GO:0042074 79 0.188
heart development GO:0007507 313 0.187
regulation of response to oxidative stress GO:1902882 2 0.187
regulation of cellular amine metabolic process GO:0033238 0 0.186
regulation of signaling GO:0023051 235 0.185
biosynthetic process GO:0009058 294 0.183
cell substrate adhesion GO:0031589 4 0.181
regulation of protein binding GO:0043393 3 0.181
adherens junction organization GO:0034332 4 0.180
neuron development GO:0048666 262 0.179
cellular macromolecule biosynthetic process GO:0034645 224 0.179
nucleobase containing compound biosynthetic process GO:0034654 205 0.173
regulation of cellular ketone metabolic process GO:0010565 7 0.173
cellular component movement GO:0006928 335 0.170
organic substance biosynthetic process GO:1901576 289 0.169
single organism nuclear import GO:1902593 3 0.167
phosphorylation GO:0016310 69 0.163
Mouse
heterocycle biosynthetic process GO:0018130 215 0.163
protein targeting to nucleus GO:0044744 3 0.161
cellular amine metabolic process GO:0044106 2 0.161
organic cyclic compound metabolic process GO:1901360 301 0.157
single organism organelle organization GO:1902589 199 0.156
cellular aromatic compound metabolic process GO:0006725 295 0.155
cellular nitrogen compound biosynthetic process GO:0044271 218 0.153
phosphorus metabolic process GO:0006793 109 0.150
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.150
cell death in response to oxidative stress GO:0036473 2 0.149
regulation of intracellular protein transport GO:0033157 3 0.148
regulation of metabolic process GO:0019222 359 0.147
cell matrix adhesion GO:0007160 4 0.144
regulation of biological quality GO:0065008 263 0.144
regulation of transcription dna templated GO:0006355 213 0.143
neuron differentiation GO:0030182 353 0.142
cell surface receptor signaling pathway GO:0007166 325 0.139
response to drug GO:0042493 3 0.138
cellular response to reactive oxygen species GO:0034614 2 0.136
regulation of establishment of protein localization GO:0070201 4 0.133
regulation of macromolecule biosynthetic process GO:0010556 225 0.127
cellular protein metabolic process GO:0044267 129 0.127
Mouse
regulation of signal transduction GO:0009966 225 0.127
regulation of response to stimulus GO:0048583 269 0.127
regulation of protein import into nucleus GO:0042306 2 0.126
negative regulation of biological process GO:0048519 304 0.125
cellular protein modification process GO:0006464 100 0.125
Mouse
adherens junction maintenance GO:0034334 2 0.124
epithelial tube morphogenesis GO:0060562 148 0.124
establishment of protein localization to organelle GO:0072594 4 0.123
gene expression GO:0010467 252 0.122
nucleocytoplasmic transport GO:0006913 4 0.121
heterocycle metabolic process GO:0046483 290 0.120
cell migration GO:0016477 237 0.118
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.118
morphogenesis of an epithelium GO:0002009 333 0.117
intracellular signal transduction GO:0035556 85 0.115
Mouse
rna biosynthetic process GO:0032774 181 0.115
regulation of cytoplasmic transport GO:1903649 4 0.114
blood vessel development GO:0001568 246 0.112
amine metabolic process GO:0009308 2 0.111
regulation of gene expression GO:0010468 265 0.110
response to abiotic stimulus GO:0009628 122 0.110
aging GO:0007568 2 0.110
macromolecule modification GO:0043412 111 0.109
Mouse
cellular component biogenesis GO:0044085 178 0.109
protein import GO:0017038 3 0.108
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.108
regulation of nucleic acid templated transcription GO:1903506 213 0.108
regulation of binding GO:0051098 3 0.107
determination of dorsal ventral asymmetry GO:0048262 34 0.107
rna metabolic process GO:0016070 219 0.107
negative regulation of intracellular transport GO:0032387 3 0.105
response to chemical GO:0042221 320 0.104
regulation of multicellular organismal process GO:0051239 277 0.103
negative regulation of signaling GO:0023057 96 0.102
regulation of sequestering of calcium ion GO:0051282 4 0.102
regulation of protein targeting GO:1903533 2 0.102
cellular nitrogen compound metabolic process GO:0034641 290 0.100
ear development GO:0043583 127 0.100
brain development GO:0007420 293 0.100
negative regulation of autophagy GO:0010507 1 0.099
positive regulation of biological process GO:0048518 253 0.099
negative regulation of protein kinase activity GO:0006469 4 0.098
positive regulation of cellular amine metabolic process GO:0033240 0 0.098
oxoacid metabolic process GO:0043436 31 0.098
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.097
negative regulation of map kinase activity GO:0043407 2 0.097
convergent extension involved in gastrulation GO:0060027 71 0.096
negative regulation of cellular process GO:0048523 283 0.095
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.092
regulation of cellular biosynthetic process GO:0031326 245 0.091
response to metal ion GO:0010038 34 0.091
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.091
response to organic substance GO:0010033 153 0.090
protein phosphorylation GO:0006468 47 0.090
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.090
cellular ketone metabolic process GO:0042180 11 0.089
nucleobase containing compound metabolic process GO:0006139 274 0.087
negative regulation of response to stimulus GO:0048585 104 0.087
response to cadmium ion GO:0046686 14 0.087
regulation of developmental process GO:0050793 247 0.085
nucleic acid templated transcription GO:0097659 181 0.084
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.084
immune system process GO:0002376 241 0.083
muscle cell differentiation GO:0042692 139 0.083
regulation of rna metabolic process GO:0051252 224 0.082
urogenital system development GO:0001655 97 0.081
nitric oxide metabolic process GO:0046209 2 0.081
regulation of neurogenesis GO:0050767 87 0.080
lateral inhibition GO:0046331 1 0.080
determination of left right symmetry GO:0007368 179 0.080
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.079
cellular response to chemical stimulus GO:0070887 157 0.079
central nervous system development GO:0007417 387 0.078
chordate embryonic development GO:0043009 271 0.078
biological adhesion GO:0022610 40 0.078
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.078
regulation of autophagy GO:0010506 3 0.078
positive regulation of apoptotic signaling pathway GO:2001235 1 0.077
regulation of cell differentiation GO:0045595 142 0.077
protein metabolic process GO:0019538 183 0.077
Mouse
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.075
regulation of nucleocytoplasmic transport GO:0046822 2 0.075
pancreas development GO:0031016 84 0.075
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.074
vasculature development GO:0001944 278 0.074
regulation of meiotic cell cycle GO:0051445 1 0.074
determination of bilateral symmetry GO:0009855 204 0.073
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.073
nuclear import GO:0051170 3 0.073
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.073
regulation of multicellular organismal development GO:2000026 223 0.073
negative regulation of kinase activity GO:0033673 4 0.072
macromolecule biosynthetic process GO:0009059 227 0.072
regulation of cellular response to oxidative stress GO:1900407 2 0.072
cellular response to organic substance GO:0071310 105 0.070
response to external stimulus GO:0009605 264 0.069
negative regulation of metabolic process GO:0009892 86 0.069
response to hydrogen peroxide GO:0042542 3 0.068
cellular response to external stimulus GO:0071496 2 0.068
wnt signaling pathway GO:0016055 80 0.067
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.066
establishment of localization GO:0051234 244 0.066
release of sequestered calcium ion into cytosol GO:0051209 3 0.066
carboxylic acid metabolic process GO:0019752 22 0.066
segmentation GO:0035282 97 0.066
regulation of protein complex assembly GO:0043254 3 0.066
regulation of protein catabolic process GO:0042176 1 0.066
dorsal convergence GO:0060030 14 0.065
ameboidal type cell migration GO:0001667 143 0.065
negative regulation of cytoplasmic transport GO:1903650 2 0.065
cellular amino acid metabolic process GO:0006520 7 0.065
organonitrogen compound metabolic process GO:1901564 74 0.065
response to superoxide GO:0000303 2 0.064
glycoprotein biosynthetic process GO:0009101 21 0.064
macromolecule glycosylation GO:0043413 9 0.064
mesodermal cell migration GO:0008078 12 0.063
positive regulation of cell cycle GO:0045787 3 0.063
single organism localization GO:1902578 225 0.063
embryonic heart tube morphogenesis GO:0003143 108 0.062
inner ear development GO:0048839 126 0.062
autophagy GO:0006914 4 0.061
generation of neurons GO:0048699 385 0.060
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.060
negative regulation of protein phosphorylation GO:0001933 4 0.060
response to hypoxia GO:0001666 25 0.060
regulation of multicellular organism growth GO:0040014 4 0.059
response to stress GO:0006950 263 0.059
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.058
maintenance of location GO:0051235 4 0.058
single organism cellular localization GO:1902580 46 0.057
larval development GO:0002164 2 0.057
cellular response to oxygen levels GO:0071453 1 0.057
regulation of phosphorus metabolic process GO:0051174 43 0.057
camera type eye development GO:0043010 222 0.057
liver development GO:0001889 96 0.056
cellular response to decreased oxygen levels GO:0036294 1 0.056
leukocyte proliferation GO:0070661 1 0.055
positive regulation of cellular component biogenesis GO:0044089 3 0.054
reactive nitrogen species metabolic process GO:2001057 0 0.054
locomotion GO:0040011 313 0.054
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.054
regionalization GO:0003002 274 0.054
positive regulation of macromolecule metabolic process GO:0010604 93 0.054
regulation of metal ion transport GO:0010959 4 0.053
cellular response to hypoxia GO:0071456 1 0.053
kidney development GO:0001822 92 0.053
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.053
multicellular organism growth GO:0035264 4 0.053
sensory organ development GO:0007423 393 0.053
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.053
detection of mechanical stimulus GO:0050982 11 0.053
growth GO:0040007 174 0.053
regulation of synapse assembly GO:0051963 3 0.052
carbohydrate derivative biosynthetic process GO:1901137 43 0.052
positive regulation of catabolic process GO:0009896 4 0.052
regulation of protein ubiquitination GO:0031396 3 0.051
negative regulation of response to cytokine stimulus GO:0060761 2 0.051
regulation of cell communication GO:0010646 232 0.051
regulation of anatomical structure morphogenesis GO:0022603 130 0.050
response to reactive oxygen species GO:0000302 5 0.050
response to endogenous stimulus GO:0009719 83 0.050
cellular response to growth factor stimulus GO:0071363 39 0.050
embryonic organ development GO:0048568 381 0.050
cell part morphogenesis GO:0032990 246 0.050
regulation of cellular protein metabolic process GO:0032268 52 0.050
negative regulation of dna replication GO:0008156 2 0.050
cell cycle process GO:0022402 53 0.050
muscle structure development GO:0061061 196 0.049
transcription from rna polymerase ii promoter GO:0006366 80 0.049
embryonic pattern specification GO:0009880 44 0.049
negative regulation of sequestering of calcium ion GO:0051283 4 0.049
response to biotic stimulus GO:0009607 97 0.049
calcium ion transport into cytosol GO:0060402 3 0.049
cellular component morphogenesis GO:0032989 336 0.049
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.048
positive regulation of metabolic process GO:0009893 108 0.048
meiotic nuclear division GO:0007126 4 0.048
organelle organization GO:0006996 227 0.047
negative regulation of protein localization to nucleus GO:1900181 2 0.047
peptidyl threonine phosphorylation GO:0018107 1 0.047
angiogenesis GO:0001525 158 0.047
response to organic cyclic compound GO:0014070 51 0.047
regulation of intracellular signal transduction GO:1902531 57 0.046
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.046
cell projection morphogenesis GO:0048858 244 0.046
heart morphogenesis GO:0003007 156 0.046
regulation of protein metabolic process GO:0051246 56 0.045
regulation of cellular component organization GO:0051128 86 0.045
response to other organism GO:0051707 97 0.045
regulation of cell matrix adhesion GO:0001952 1 0.045
regulation of epithelial to mesenchymal transition GO:0010717 3 0.045
cell cell signaling GO:0007267 52 0.045
cellular localization GO:0051641 97 0.044
embryonic skeletal system development GO:0048706 97 0.044
cellular component assembly GO:0022607 170 0.044
developmental growth GO:0048589 166 0.044
anterior posterior pattern specification GO:0009952 152 0.043
negative regulation of hormone secretion GO:0046888 2 0.042
connective tissue development GO:0061448 99 0.042
cellular carbohydrate metabolic process GO:0044262 4 0.042
negative regulation of nuclear division GO:0051784 3 0.042
myeloid cell differentiation GO:0030099 86 0.041
organic acid metabolic process GO:0006082 31 0.041
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.041
negative regulation of cellular metabolic process GO:0031324 77 0.041
negative regulation of protein import into nucleus GO:0042308 2 0.041
regulation of synapse organization GO:0050807 3 0.041
regulation of reproductive process GO:2000241 4 0.041
regulation of phosphorylation GO:0042325 26 0.040
cell adhesion GO:0007155 40 0.040
erk1 and erk2 cascade GO:0070371 4 0.040
stem cell differentiation GO:0048863 117 0.040
regulation of cell substrate adhesion GO:0010810 1 0.040
regulation of cell cycle process GO:0010564 20 0.040
eye development GO:0001654 277 0.040
sequestering of metal ion GO:0051238 3 0.040
wound healing GO:0042060 90 0.039
response to inorganic substance GO:0010035 38 0.039
positive regulation of rna metabolic process GO:0051254 59 0.039
adult behavior GO:0030534 2 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.039
regulation of mrna processing GO:0050684 3 0.039
central nervous system neuron differentiation GO:0021953 74 0.039
response to growth factor GO:0070848 39 0.038
cell morphogenesis GO:0000902 289 0.038
small molecule metabolic process GO:0044281 77 0.038
cell motility GO:0048870 244 0.038
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.038
lateral line development GO:0048882 66 0.038
striated muscle cell differentiation GO:0051146 129 0.037
regulation of protein phosphorylation GO:0001932 18 0.037
cell growth GO:0016049 57 0.037
skeletal system development GO:0001501 181 0.037
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.037
negative regulation of mapk cascade GO:0043409 4 0.036
single organism biosynthetic process GO:0044711 71 0.036
regulation of wound healing GO:0061041 2 0.036
positive regulation of reproductive process GO:2000243 2 0.036
cellular response to lipopolysaccharide GO:0071222 3 0.036
regulation of bone mineralization GO:0030500 2 0.036
negative regulation of cell communication GO:0010648 96 0.036
negative regulation of cellular biosynthetic process GO:0031327 55 0.035
antimicrobial humoral response GO:0019730 2 0.035
negative regulation of cell fate commitment GO:0010454 13 0.035
positive regulation of cellular catabolic process GO:0031331 3 0.035
cellular response to nutrient levels GO:0031669 2 0.035
negative regulation of intracellular protein transport GO:0090317 3 0.035
response to fluid shear stress GO:0034405 2 0.035
protein localization GO:0008104 40 0.035
nephron tubule morphogenesis GO:0072078 1 0.035
dorsal ventral pattern formation GO:0009953 125 0.034
regulation of cell cycle GO:0051726 52 0.034
convergent extension GO:0060026 118 0.034
cell cycle GO:0007049 93 0.034
endocrine pancreas development GO:0031018 27 0.034
ossification GO:0001503 23 0.034
cellular response to xenobiotic stimulus GO:0071466 35 0.034
melanin metabolic process GO:0006582 2 0.034
response to oxygen levels GO:0070482 25 0.033
signal transduction by phosphorylation GO:0023014 18 0.033
Mouse
negative regulation of signal transduction GO:0009968 94 0.033
stem cell proliferation GO:0072089 4 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.033
regulation of neuron differentiation GO:0045664 56 0.033
secondary metabolic process GO:0019748 3 0.033
regulation of blood pressure GO:0008217 1 0.033
hepatocyte proliferation GO:0072574 2 0.032
positive regulation of epithelial cell differentiation GO:0030858 2 0.032
intracellular transport GO:0046907 32 0.032
protein polymerization GO:0051258 4 0.032
striated muscle tissue development GO:0014706 110 0.032
regulation of cell activation GO:0050865 1 0.032
glycosylation GO:0070085 11 0.032
negative regulation of catabolic process GO:0009895 3 0.032
positive regulation of cellular protein metabolic process GO:0032270 22 0.032
negative regulation of catalytic activity GO:0043086 21 0.031
regeneration GO:0031099 91 0.031
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.031
cytoskeleton organization GO:0007010 96 0.031
response to external biotic stimulus GO:0043207 97 0.031
response to oxygen radical GO:0000305 2 0.031
response to corticosteroid GO:0031960 1 0.030
hypothalamus development GO:0021854 14 0.030
positive regulation of cell adhesion GO:0045785 1 0.030
sensory organ morphogenesis GO:0090596 200 0.030
regulation of cyclase activity GO:0031279 12 0.030
positive regulation of transcription dna templated GO:0045893 57 0.030
mapk cascade GO:0000165 18 0.030
Mouse
hepaticobiliary system development GO:0061008 98 0.030
sprouting angiogenesis GO:0002040 53 0.030
somite development GO:0061053 96 0.030
regulation of wnt signaling pathway GO:0030111 53 0.030
cell junction maintenance GO:0034331 2 0.029
transport GO:0006810 220 0.029
bmp signaling pathway GO:0030509 52 0.029
regulation of erk1 and erk2 cascade GO:0070372 4 0.029
enzyme linked receptor protein signaling pathway GO:0007167 106 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
positive regulation of protein metabolic process GO:0051247 23 0.029
mononuclear cell proliferation GO:0032943 1 0.029
cellular protein localization GO:0034613 20 0.029
cell substrate junction assembly GO:0007044 2 0.029
primary neural tube formation GO:0014020 1 0.029
glycoprotein metabolic process GO:0009100 23 0.029
cellular response to starvation GO:0009267 1 0.029
positive regulation of nucleic acid templated transcription GO:1903508 57 0.029
regulation of nervous system development GO:0051960 90 0.029
response to oxygen containing compound GO:1901700 55 0.028
hindbrain development GO:0030902 91 0.028
positive regulation of transport GO:0051050 2 0.028
positive regulation of signal transduction GO:0009967 56 0.028
neuron projection development GO:0031175 180 0.028
negative regulation of secretion GO:0051048 2 0.028
somatic stem cell maintenance GO:0035019 1 0.028
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.028
gland development GO:0048732 143 0.028
cytosolic calcium ion transport GO:0060401 3 0.028
regulation of canonical wnt signaling pathway GO:0060828 34 0.028
localization of cell GO:0051674 244 0.028
centrosome organization GO:0051297 1 0.028
regulation of anterior head development GO:2000742 2 0.028
axonogenesis GO:0007409 152 0.028
negative regulation of mitosis GO:0045839 3 0.028
somatic muscle development GO:0007525 4 0.028
tissue regeneration GO:0042246 74 0.027
regulation of cellular component movement GO:0051270 55 0.027
nuclear division GO:0000280 23 0.027
regulation of dendrite development GO:0050773 3 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.026
tube closure GO:0060606 1 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
thrombocyte differentiation GO:0002574 4 0.026
positive regulation of striated muscle cell differentiation GO:0051155 1 0.026
positive regulation of wound healing GO:0090303 1 0.026
renal system development GO:0072001 94 0.026
organelle fission GO:0048285 23 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
regulation of protein polymerization GO:0032271 2 0.026
organelle assembly GO:0070925 110 0.026
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.026
lateral line system development GO:0048925 76 0.026
negative regulation of apoptotic signaling pathway GO:2001234 10 0.026
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
blood vessel morphogenesis GO:0048514 216 0.026
cell cell signaling involved in cell fate commitment GO:0045168 12 0.026
development of primary female sexual characteristics GO:0046545 4 0.026
phagocytosis GO:0006909 3 0.025
adherens junction assembly GO:0034333 1 0.025
positive regulation of gene expression GO:0010628 71 0.025
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.025
cellular calcium ion homeostasis GO:0006874 13 0.025
positive regulation of nervous system development GO:0051962 25 0.025
regulation of jun kinase activity GO:0043506 3 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
nitric oxide biosynthetic process GO:0006809 2 0.025
response to oxidative stress GO:0006979 11 0.025
cognition GO:0050890 1 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.025
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
positive regulation of dna metabolic process GO:0051054 1 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
germ line stem cell maintenance GO:0030718 2 0.024
kidney epithelium development GO:0072073 23 0.024
embryonic limb morphogenesis GO:0030326 2 0.024
chemical homeostasis GO:0048878 49 0.024
regulation of localization GO:0032879 104 0.024
cell cycle arrest GO:0007050 1 0.024
negative regulation of molecular function GO:0044092 23 0.024
inositol lipid mediated signaling GO:0048017 2 0.024
single organism intracellular transport GO:1902582 25 0.024
actin polymerization or depolymerization GO:0008154 2 0.023
protein o linked glycosylation GO:0006493 4 0.023
positive regulation of signaling GO:0023056 56 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
system process GO:0003008 185 0.023
cellular component maintenance GO:0043954 3 0.023
positive regulation of chromosome organization GO:2001252 1 0.023
regulation of apoptotic signaling pathway GO:2001233 12 0.023
determination of dorsal identity GO:0048263 13 0.023
catecholamine metabolic process GO:0006584 2 0.023
specification of symmetry GO:0009799 204 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
regulation of transport GO:0051049 45 0.023
axis specification GO:0009798 43 0.023
forebrain development GO:0030900 96 0.023
oocyte anterior posterior axis specification GO:0007314 4 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
metal ion transport GO:0030001 58 0.023
regulation of cell fate commitment GO:0010453 22 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
central nervous system neuron axonogenesis GO:0021955 18 0.023
defense response to bacterium GO:0042742 22 0.023
lymphocyte proliferation GO:0046651 1 0.022
mesenchymal cell differentiation GO:0048762 87 0.022
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.022
female sex differentiation GO:0046660 4 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
stem cell maintenance GO:0019827 4 0.022
tissue remodeling GO:0048771 4 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.022
positive regulation of muscle cell differentiation GO:0051149 1 0.022
regulation of response to cytokine stimulus GO:0060759 3 0.022
phagocytosis engulfment GO:0006911 1 0.022
i kappab kinase nf kappab signaling GO:0007249 4 0.022
sarcomere organization GO:0045214 26 0.022
mitotic cell cycle GO:0000278 64 0.022
regulation of catalytic activity GO:0050790 55 0.022
positive regulation of rna biosynthetic process GO:1902680 57 0.022
response to monosaccharide GO:0034284 3 0.022

mapk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
musculoskeletal system disease DOID:17 0 0.042
bone disease DOID:0080001 0 0.039
connective tissue disease DOID:65 0 0.039
cardiovascular system disease DOID:1287 0 0.036
muscular disease DOID:0080000 0 0.029
muscle tissue disease DOID:66 0 0.029