Danio rerio

39 known processes

mapk8b

mitogen-activated protein kinase 8b

(Aliases: JNK,mapk8,JNK1,zgc:112379)

mapk8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.421
Human Yeast Mouse Rat Fly
nucleobase containing compound metabolic process GO:0006139 274 0.417
Yeast Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.374
Yeast Rat
gastrulation GO:0007369 208 0.364
regulation of biosynthetic process GO:0009889 250 0.334
Yeast Rat
cellular biosynthetic process GO:0044249 286 0.325
Yeast Rat
aromatic compound biosynthetic process GO:0019438 217 0.315
Yeast Rat
organic substance biosynthetic process GO:1901576 289 0.307
Yeast Rat
immune system process GO:0002376 241 0.289
Fly
peptidyl serine phosphorylation GO:0018105 1 0.285
Human
regulation of macromolecule metabolic process GO:0060255 317 0.282
Human Yeast Mouse Rat Fly
positive regulation of metabolic process GO:0009893 108 0.281
Human Yeast Rat Fly
determination of left right symmetry GO:0007368 179 0.266
Fly
cellular macromolecule metabolic process GO:0044260 391 0.263
Human Yeast Mouse Rat Worm Fly
nucleic acid templated transcription GO:0097659 181 0.258
Yeast Rat
digestive tract development GO:0048565 265 0.256
Fly
biosynthetic process GO:0009058 294 0.250
Yeast Rat
inner ear development GO:0048839 126 0.210
rna biosynthetic process GO:0032774 181 0.208
Yeast Rat
digestive tract morphogenesis GO:0048546 231 0.204
Fly
cellular component movement GO:0006928 335 0.201
Rat Worm Fly
signal transduction GO:0007165 455 0.194
response to external stimulus GO:0009605 264 0.191
Human Fly
organic cyclic compound metabolic process GO:1901360 301 0.181
Yeast Rat Fly
nitrogen compound metabolic process GO:0006807 319 0.179
Yeast Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.174
Yeast Rat
single organism metabolic process GO:0044710 217 0.169
regulation of cellular metabolic process GO:0031323 320 0.161
Human Yeast Rat Fly
nucleic acid metabolic process GO:0090304 244 0.151
Yeast Rat
positive regulation of transport GO:0051050 2 0.151
rna metabolic process GO:0016070 219 0.147
Yeast Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.146
regulation of multicellular organismal process GO:0051239 277 0.144
Mouse
regulation of localization GO:0032879 104 0.141
Human Rat
cell migration involved in gastrulation GO:0042074 79 0.136
intracellular signal transduction GO:0035556 85 0.132
protein localization to nucleus GO:0034504 3 0.132
regulation of nitrogen compound metabolic process GO:0051171 251 0.128
Yeast Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.126
Yeast Rat
stem cell maintenance GO:0019827 4 0.125
digestive system development GO:0055123 289 0.122
Fly
lateral line system development GO:0048925 76 0.121
sequestering of metal ion GO:0051238 3 0.120
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.118
embryonic organ development GO:0048568 381 0.117
Fly
phosphorus metabolic process GO:0006793 109 0.114
regulation of anterior head development GO:2000742 2 0.110
ear development GO:0043583 127 0.109
ameboidal type cell migration GO:0001667 143 0.109
Fly
negative regulation of biological process GO:0048519 304 0.109
Human Yeast Rat Fly
generation of neurons GO:0048699 385 0.107
Rat Fly
positive regulation of biosynthetic process GO:0009891 68 0.107
Yeast Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.107
Yeast Rat
regulation of biological quality GO:0065008 263 0.107
system process GO:0003008 185 0.106
positive regulation of transcription dna templated GO:0045893 57 0.106
Yeast
heterocycle biosynthetic process GO:0018130 215 0.104
Yeast Rat
organonitrogen compound metabolic process GO:1901564 74 0.103
regulation of cellular biosynthetic process GO:0031326 245 0.102
Yeast Rat
embryonic heart tube morphogenesis GO:0003143 108 0.101
neuron development GO:0048666 262 0.100
Rat Fly
regulation of multicellular organism growth GO:0040014 4 0.097
myeloid cell differentiation GO:0030099 86 0.097
anterior head development GO:0097065 2 0.096
cellular response to lipid GO:0071396 39 0.093
Human
mesoderm development GO:0007498 88 0.093
multicellular organism growth GO:0035264 4 0.093
regulation of wound healing GO:0061041 2 0.090
cell migration GO:0016477 237 0.090
Rat Fly
oxoacid metabolic process GO:0043436 31 0.090
central nervous system neuron differentiation GO:0021953 74 0.089
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.088
cellular response to toxic substance GO:0097237 1 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.086
Yeast Rat Fly
gall bladder development GO:0061010 1 0.084
cellular response to hypoxia GO:0071456 1 0.083
neuron neuron synaptic transmission GO:0007270 1 0.082
regulation of signaling GO:0023051 235 0.081
Mouse Fly
heterocycle metabolic process GO:0046483 290 0.081
Yeast Rat
localization of cell GO:0051674 244 0.079
Rat Fly
mediolateral intercalation GO:0060031 3 0.078
regulation of protein complex assembly GO:0043254 3 0.078
Rat
programmed cell death GO:0012501 119 0.075
Human Mouse Rat
negative regulation of mitosis GO:0045839 3 0.073
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.073
sequestering of calcium ion GO:0051208 3 0.073
hepatocyte proliferation GO:0072574 2 0.073
positive regulation of cellular process GO:0048522 201 0.072
Yeast Mouse Rat Fly
mesodermal cell differentiation GO:0048333 21 0.072
cellular ketone metabolic process GO:0042180 11 0.072
larval development GO:0002164 2 0.071
negative regulation of protein complex assembly GO:0031333 1 0.070
specification of axis polarity GO:0065001 4 0.069
energy homeostasis GO:0097009 3 0.068
homeostatic process GO:0042592 142 0.066
regulation of nucleic acid templated transcription GO:1903506 213 0.065
Yeast Rat
positive regulation of gene expression GO:0010628 71 0.065
Human Yeast
response to monosaccharide GO:0034284 3 0.063
cell cycle GO:0007049 93 0.063
Yeast
gland development GO:0048732 143 0.062
Zebrafish
hemopoiesis GO:0030097 183 0.062
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.062
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.062
Yeast
nucleobase containing compound biosynthetic process GO:0034654 205 0.062
Yeast Rat
response to stress GO:0006950 263 0.061
macromolecule biosynthetic process GO:0009059 227 0.060
Yeast Rat
negative regulation of sequestering of calcium ion GO:0051283 4 0.060
otolith development GO:0048840 32 0.056
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.055
cellular amino acid metabolic process GO:0006520 7 0.055
cellular response to reactive oxygen species GO:0034614 2 0.055
Mouse Fly
positive regulation of camp metabolic process GO:0030816 2 0.055
regulation of heart rate GO:0002027 5 0.054
regulation of cell adhesion GO:0030155 15 0.054
chordate embryonic development GO:0043009 271 0.054
carboxylic acid metabolic process GO:0019752 22 0.053
regulation of transcription dna templated GO:0006355 213 0.052
Yeast Rat
response to organic substance GO:0010033 153 0.052
Human Rat
convergent extension involved in gastrulation GO:0060027 71 0.052
protein polymerization GO:0051258 4 0.051
Rat
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.051
negative regulation of nuclear division GO:0051784 3 0.051
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.051
positive regulation of multicellular organismal process GO:0051240 52 0.051
Mouse
wound healing GO:0042060 90 0.051
Fly
response to hydrogen peroxide GO:0042542 3 0.050
Mouse Rat
neuron projection development GO:0031175 180 0.050
Rat Fly
response to endogenous stimulus GO:0009719 83 0.049
Rat
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.049
regulation of protein transport GO:0051223 3 0.049
cell cell signaling GO:0007267 52 0.048
regulation of sequestering of calcium ion GO:0051282 4 0.048
camera type eye development GO:0043010 222 0.048
extrinsic apoptotic signaling pathway GO:0097191 3 0.047
neurotransmitter secretion GO:0007269 2 0.046
response to drug GO:0042493 3 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Fly
signal transduction by phosphorylation GO:0023014 18 0.045
cellular response to decreased oxygen levels GO:0036294 1 0.045
myeloid cell development GO:0061515 32 0.045
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
Yeast Rat
regulation of cytokine production GO:0001817 3 0.043
response to growth factor GO:0070848 39 0.043
cell morphogenesis involved in differentiation GO:0000904 195 0.043
Fly
spinal cord anterior posterior patterning GO:0021512 1 0.042
detection of abiotic stimulus GO:0009582 24 0.042
negative regulation of response to external stimulus GO:0032102 9 0.042
phosphorylation GO:0016310 69 0.041
regulation of jak stat cascade GO:0046425 3 0.041
opioid receptor signaling pathway GO:0038003 3 0.041
regulation of signal transduction GO:0009966 225 0.041
Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.041
Yeast Rat
positive regulation of secretion by cell GO:1903532 1 0.041
convergent extension GO:0060026 118 0.041
regulation of response to cytokine stimulus GO:0060759 3 0.041
positive regulation of biological process GO:0048518 253 0.040
Human Yeast Mouse Rat Fly
cell cycle process GO:0022402 53 0.040
Yeast
formation of primary germ layer GO:0001704 62 0.040
positive regulation of reproductive process GO:2000243 2 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
morphogenesis of an epithelium GO:0002009 333 0.038
Fly
organic substance transport GO:0071702 58 0.038
regulation of primary metabolic process GO:0080090 311 0.038
Human Yeast Rat Fly
mesoderm morphogenesis GO:0048332 51 0.037
positive regulation of cell cycle GO:0045787 3 0.037
regulation of cell differentiation GO:0045595 142 0.036
Yeast
embryonic camera type eye morphogenesis GO:0048596 19 0.036
regulation of blood pressure GO:0008217 1 0.036
liver development GO:0001889 96 0.035
Zebrafish
response to food GO:0032094 1 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
Yeast Rat
embryonic skeletal system development GO:0048706 97 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
regulation of multicellular organismal development GO:2000026 223 0.034
Mouse
regulation of ion transmembrane transporter activity GO:0032412 2 0.034
cellular hormone metabolic process GO:0034754 19 0.034
meiotic nuclear division GO:0007126 4 0.034
macromolecule modification GO:0043412 111 0.034
Human Yeast Mouse Rat Worm Fly
positive regulation of signaling GO:0023056 56 0.034
Mouse
estrogen metabolic process GO:0008210 2 0.034
positive regulation of rna biosynthetic process GO:1902680 57 0.033
Yeast
neuron projection extension GO:1990138 45 0.033
Fly
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
regulation of response to stimulus GO:0048583 269 0.033
Mouse Fly
cell death GO:0008219 121 0.032
Human Mouse Rat
regulation of circadian rhythm GO:0042752 4 0.032
locomotion GO:0040011 313 0.032
Rat Fly
stem cell differentiation GO:0048863 117 0.032
thrombocyte differentiation GO:0002574 4 0.031
pancreas development GO:0031016 84 0.031
otic placode formation GO:0043049 23 0.031
cellular component assembly GO:0022607 170 0.031
Yeast Rat
regulation of phosphate metabolic process GO:0019220 43 0.030
Fly
response to hexose GO:0009746 3 0.030
regulation of reproductive process GO:2000241 4 0.030
diencephalon development GO:0021536 58 0.030
somite development GO:0061053 96 0.030
protein localization GO:0008104 40 0.030
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.030
Yeast
positive regulation of cellular metabolic process GO:0031325 94 0.029
Yeast Rat Fly
cellular protein modification process GO:0006464 100 0.029
Human Yeast Mouse Rat Worm Fly
eye development GO:0001654 277 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
aging GO:0007568 2 0.029
Worm
regulation of cell activation GO:0050865 1 0.029
optic placode formation GO:0001743 4 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
Yeast Rat
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.029
heart looping GO:0001947 94 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
Yeast
regulation of gastrulation GO:0010470 24 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
negative regulation of epithelial cell proliferation GO:0050680 1 0.028
regulation of locomotion GO:0040012 55 0.028
Rat
germ line stem cell maintenance GO:0030718 2 0.028
regulation of cell communication GO:0010646 232 0.028
Mouse Fly
regulation of cellular component organization GO:0051128 86 0.028
Human Rat
positive regulation of secretion GO:0051047 1 0.027
cellular response to oxygen levels GO:0071453 1 0.027
positive regulation of rna metabolic process GO:0051254 59 0.027
Yeast
axon extension GO:0048675 45 0.027
Fly
endocrine system development GO:0035270 65 0.027
regulation of cell motility GO:2000145 46 0.027
Rat
regulation of cellular amine metabolic process GO:0033238 0 0.026
nuclear transport GO:0051169 4 0.026
specification of symmetry GO:0009799 204 0.026
regulation of cell cell adhesion GO:0022407 13 0.026
lymphocyte proliferation GO:0046651 1 0.026
cellular response to organic substance GO:0071310 105 0.026
Human
negative regulation of response to stimulus GO:0048585 104 0.026
Fly
neuron differentiation GO:0030182 353 0.026
Rat Fly
protein metabolic process GO:0019538 183 0.026
Human Yeast Mouse Rat Worm Fly
cellular amine metabolic process GO:0044106 2 0.026
transcription dna templated GO:0006351 181 0.026
Yeast Rat
response to chemical GO:0042221 320 0.025
Human Yeast Mouse Rat Fly
response to lipopolysaccharide GO:0032496 13 0.025
Human
cognition GO:0050890 1 0.025
response to glucose GO:0009749 3 0.025
regulation of inflammatory response GO:0050727 2 0.025
catechol containing compound metabolic process GO:0009712 2 0.025
growth GO:0040007 174 0.025
Fly
response to abiotic stimulus GO:0009628 122 0.025
Human Yeast Rat Worm Fly
response to wounding GO:0009611 116 0.025
Fly
biological adhesion GO:0022610 40 0.025
regulation of response to nutrient levels GO:0032107 1 0.024
regulation of cell death GO:0010941 103 0.024
Human Mouse Rat
cellular response to growth factor stimulus GO:0071363 39 0.024
muscle cell differentiation GO:0042692 139 0.024
single organism organelle organization GO:1902589 199 0.024
Human Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.024
Human Yeast Rat
positive regulation of cellular component biogenesis GO:0044089 3 0.024
Rat
internal peptidyl lysine acetylation GO:0018393 2 0.024
hormone secretion GO:0046879 2 0.024
peptidyl serine modification GO:0018209 2 0.024
Human
gene expression GO:0010467 252 0.023
Human Yeast Mouse Rat
forebrain development GO:0030900 96 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.023
Yeast Rat
muscle cell development GO:0055001 115 0.023
otic vesicle development GO:0071599 42 0.023
somitogenesis GO:0001756 87 0.023
amine metabolic process GO:0009308 2 0.023
regulation of transport GO:0051049 45 0.022
leukocyte activation GO:0045321 12 0.022
cell substrate adhesion GO:0031589 4 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.022
response to decreased oxygen levels GO:0036293 25 0.022
neuropeptide signaling pathway GO:0007218 11 0.022
regulation of defense response GO:0031347 14 0.021
connective tissue development GO:0061448 99 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
Fly
dorsal convergence GO:0060030 14 0.021
glutamate receptor signaling pathway GO:0007215 1 0.021
mononuclear cell proliferation GO:0032943 1 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
determination of heart left right asymmetry GO:0061371 117 0.020
response to oxygen levels GO:0070482 25 0.020
protein phosphorylation GO:0006468 47 0.020
Human Yeast Mouse Rat Worm Fly
cytosolic calcium ion transport GO:0060401 3 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
hepatic duct development GO:0061011 2 0.020
cell fate commitment GO:0045165 99 0.020
adult behavior GO:0030534 2 0.020
regulation of embryonic development GO:0045995 47 0.020
mesoderm formation GO:0001707 43 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.019
Yeast Rat
leukocyte proliferation GO:0070661 1 0.019
synaptic transmission cholinergic GO:0007271 4 0.019
small molecule metabolic process GO:0044281 77 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
Human
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of cellular component movement GO:0051270 55 0.019
Rat
regulation of cellular response to oxidative stress GO:1900407 2 0.019
protein import into nucleus GO:0006606 3 0.019
hepaticobiliary system development GO:0061008 98 0.019
Zebrafish
cellular component biogenesis GO:0044085 178 0.019
Yeast Rat
negative regulation of secretion GO:0051048 2 0.019
regulation of circadian sleep wake cycle GO:0042749 1 0.019
organelle organization GO:0006996 227 0.019
Human Rat
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.019
positive regulation of cell adhesion GO:0045785 1 0.018
regulation of protein metabolic process GO:0051246 56 0.018
Human Fly
protein import GO:0017038 3 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
Yeast
cell morphogenesis GO:0000902 289 0.018
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
Yeast Rat
habenula development GO:0021986 9 0.018
regulation of gene expression GO:0010468 265 0.018
Human Yeast Mouse Rat
regulation of response to external stimulus GO:0032101 31 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
axis specification GO:0009798 43 0.018
cell motility GO:0048870 244 0.018
Rat Fly
multicellular organismal homeostasis GO:0048871 29 0.018
wnt signaling pathway GO:0016055 80 0.018
cell proliferation GO:0008283 80 0.018
neurotransmitter transport GO:0006836 2 0.017
regulation of calcium ion transport GO:0051924 2 0.017
regulation of intracellular signal transduction GO:1902531 57 0.017
Fly
cell projection morphogenesis GO:0048858 244 0.017
Fly
kidney development GO:0001822 92 0.017
negative regulation of cell differentiation GO:0045596 46 0.017
Yeast
carbohydrate homeostasis GO:0033500 1 0.017
neuron projection guidance GO:0097485 86 0.017
Fly
regulation of hormone secretion GO:0046883 2 0.017
regulation of membrane potential GO:0042391 23 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
locomotor rhythm GO:0045475 3 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.016
ovulation cycle GO:0042698 2 0.016
positive regulation of epithelial cell differentiation GO:0030858 2 0.016
brain development GO:0007420 293 0.016
maintenance of location GO:0051235 4 0.016
negative regulation of cellular process GO:0048523 283 0.016
Human Yeast Rat Fly
ovulation cycle process GO:0022602 2 0.016
chemotaxis GO:0006935 104 0.016
Fly
response to ethanol GO:0045471 6 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
response to corticosteroid GO:0031960 1 0.016
regulation of apoptotic process GO:0042981 98 0.016
Human Mouse Rat
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.015
regulation of developmental process GO:0050793 247 0.015
Yeast Mouse
organic acid metabolic process GO:0006082 31 0.015
cellular localization GO:0051641 97 0.015
Worm
response to lipid GO:0033993 60 0.015
Human Rat
heart contraction GO:0060047 71 0.015
macromolecular complex assembly GO:0065003 35 0.015
Rat
positive regulation of striated muscle cell differentiation GO:0051155 1 0.015
immune system development GO:0002520 191 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
negative regulation of gene expression GO:0010629 65 0.015
negative regulation of signaling GO:0023057 96 0.015
Fly
cellular response to biotic stimulus GO:0071216 3 0.015
Human
sensory system development GO:0048880 76 0.015
regulation of cell cycle process GO:0010564 20 0.015
Yeast
sensory organ morphogenesis GO:0090596 200 0.015
regulation of protein catabolic process GO:0042176 1 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
cellular component morphogenesis GO:0032989 336 0.014
Yeast Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
Mouse
regulation of nucleotide biosynthetic process GO:0030808 15 0.014
regulation of dna templated transcription in response to stress GO:0043620 0 0.014
Yeast
cell adhesion GO:0007155 40 0.014
positive regulation of cell activation GO:0050867 1 0.014
axonogenesis GO:0007409 152 0.014
Fly
regulation of mitotic cell cycle GO:0007346 25 0.014
peripheral nervous system neuron differentiation GO:0048934 28 0.014
embryonic heart tube development GO:0035050 133 0.014
cell death in response to oxidative stress GO:0036473 2 0.014
olfactory lobe development GO:0021988 4 0.014
epithelium regeneration GO:1990399 14 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of response to wounding GO:1903034 11 0.014
cell part morphogenesis GO:0032990 246 0.014
Fly
cell adhesion mediated by integrin GO:0033627 1 0.014
positive regulation of multi organism process GO:0043902 3 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.014
establishment of localization GO:0051234 244 0.014
Worm Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
embryonic limb morphogenesis GO:0030326 2 0.014
reproduction GO:0000003 40 0.014
Yeast Fly
single organism behavior GO:0044708 24 0.014
heart jogging GO:0003146 40 0.014
endoderm development GO:0007492 49 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
positive regulation of defense response GO:0031349 9 0.013
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.013
tissue homeostasis GO:0001894 25 0.013
positive regulation of immune effector process GO:0002699 3 0.013
developmental cell growth GO:0048588 52 0.013
Fly
negative regulation of map kinase activity GO:0043407 2 0.013
Fly
response to organic cyclic compound GO:0014070 51 0.013
Rat
response to inorganic substance GO:0010035 38 0.013
Mouse Rat Fly
response to carbohydrate GO:0009743 3 0.013
somatic stem cell maintenance GO:0035019 1 0.013
circulatory system process GO:0003013 87 0.013
single organism localization GO:1902578 225 0.013
Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.013
Human Mouse Fly
axon extension involved in axon guidance GO:0048846 10 0.013
hormone transport GO:0009914 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
Human
determination of dorsal identity GO:0048263 13 0.012
regulation of response to stress GO:0080134 36 0.012
Fly
skeletal muscle organ development GO:0060538 78 0.012
forebrain cell migration GO:0021885 1 0.012
inner ear morphogenesis GO:0042472 63 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
pharyngeal muscle development GO:0043282 4 0.012
urogenital system development GO:0001655 97 0.012
embryonic camera type eye formation GO:0060900 10 0.012
response to bacterium GO:0009617 58 0.012
Human Fly
negative regulation of stem cell differentiation GO:2000737 2 0.012
multi organism process GO:0051704 134 0.012
Human Yeast Fly
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
myofibril assembly GO:0030239 48 0.012
cellular response to radiation GO:0071478 4 0.012
peptide transport GO:0015833 1 0.012
tissue regeneration GO:0042246 74 0.012
response to cadmium ion GO:0046686 14 0.012
Mouse Fly
regulation of hormone levels GO:0010817 21 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
ion transport GO:0006811 114 0.012
hypothalamus development GO:0021854 14 0.012
regulation of bone mineralization GO:0030500 2 0.012
tissue remodeling GO:0048771 4 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
circadian sleep wake cycle GO:0042745 2 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
phagocytosis GO:0006909 3 0.011
Fly
cardiac cell fate commitment GO:0060911 1 0.011
negative regulation of cell communication GO:0010648 96 0.011
Fly
regulation of phosphorus metabolic process GO:0051174 43 0.011
Fly
response to unfolded protein GO:0006986 2 0.011
tube morphogenesis GO:0035239 349 0.011
Fly
neuromuscular synaptic transmission GO:0007274 2 0.011
endocytosis GO:0006897 16 0.011
Fly
negative regulation of programmed cell death GO:0043069 58 0.011
Human Rat
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.011
taxis GO:0042330 109 0.011
Fly
embryonic eye morphogenesis GO:0048048 30 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
protein modification process GO:0036211 100 0.011
Human Yeast Mouse Rat Worm Fly
negative regulation of defense response GO:0031348 2 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
single organism cell adhesion GO:0098602 29 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
mitochondrion organization GO:0007005 4 0.011
positive regulation of developmental process GO:0051094 50 0.011
Mouse
peripheral nervous system neuron development GO:0048935 22 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
muscle structure development GO:0061061 196 0.011
neurological system process GO:0050877 62 0.011
nuclear export GO:0051168 1 0.011
positive regulation of phosphorus metabolic process GO:0010562 21 0.011
intracellular mrna localization GO:0008298 1 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
cellular protein localization GO:0034613 20 0.010
regulation of cell cycle GO:0051726 52 0.010
Yeast
cellular response to extracellular stimulus GO:0031668 2 0.010
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.010
transport GO:0006810 220 0.010
Worm Fly
establishment of protein localization to organelle GO:0072594 4 0.010
single organism biosynthetic process GO:0044711 71 0.010
Yeast
bone remodeling GO:0046849 2 0.010
cell division GO:0051301 20 0.010
ectodermal placode development GO:0071696 37 0.010
cell projection organization GO:0030030 284 0.010
Rat Fly
calcium ion transport GO:0006816 18 0.010
protein acylation GO:0043543 3 0.010
response to light stimulus GO:0009416 46 0.010
Human
blood circulation GO:0008015 87 0.010
cellular response to unfolded protein GO:0034620 2 0.010
sensory organ development GO:0007423 393 0.010
blood vessel development GO:0001568 246 0.010
cellular calcium ion homeostasis GO:0006874 13 0.010

mapk8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
organ system cancer DOID:0050686 0 0.019
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
cardiovascular system disease DOID:1287 0 0.017
disease of metabolism DOID:0014667 0 0.013
bone development disease DOID:0080006 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012