Danio rerio

0 known processes

march6

membrane-associated ring finger (C3HC4) 6

(Aliases: im:7161807,si:dkey-40c17.2,wu:fa98a02)

march6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component biogenesis GO:0044085 178 0.119
centrosome cycle GO:0007098 1 0.113
cognition GO:0050890 1 0.107
centrosome organization GO:0051297 1 0.099
gtp metabolic process GO:0046039 4 0.095
signal transduction GO:0007165 455 0.092
regulation of protein transport GO:0051223 3 0.082
protein polyubiquitination GO:0000209 4 0.079
tube morphogenesis GO:0035239 349 0.079
microtubule organizing center organization GO:0031023 1 0.078
regulation of establishment of protein localization GO:0070201 4 0.077
nucleobase containing compound metabolic process GO:0006139 274 0.075
protein metabolic process GO:0019538 183 0.074
negative regulation of biological process GO:0048519 304 0.073
larval development GO:0002164 2 0.072
organic cyclic compound metabolic process GO:1901360 301 0.070
endoplasmic reticulum unfolded protein response GO:0030968 2 0.069
heterocycle metabolic process GO:0046483 290 0.068
gtp catabolic process GO:0006184 2 0.067
protein import into nucleus GO:0006606 3 0.066
autophagy GO:0006914 4 0.066
cell migration GO:0016477 237 0.066
single organism metabolic process GO:0044710 217 0.065
protein localization to nucleus GO:0034504 3 0.064
regulation of biosynthetic process GO:0009889 250 0.062
regulation of metabolic process GO:0019222 359 0.061
neuron development GO:0048666 262 0.061
meiotic nuclear division GO:0007126 4 0.061
determination of left right symmetry GO:0007368 179 0.060
positive regulation of transport GO:0051050 2 0.060
cellular component assembly GO:0022607 170 0.059
positive regulation of cellular catabolic process GO:0031331 3 0.058
cellular biosynthetic process GO:0044249 286 0.058
nitrogen compound metabolic process GO:0006807 319 0.058
cellular macromolecule metabolic process GO:0044260 391 0.057
establishment of protein localization to organelle GO:0072594 4 0.057
response to topologically incorrect protein GO:0035966 2 0.056
cellular aromatic compound metabolic process GO:0006725 295 0.054
organic substance biosynthetic process GO:1901576 289 0.052
regulation of circadian rhythm GO:0042752 4 0.052
aging GO:0007568 2 0.051
endosomal transport GO:0016197 2 0.051
organelle assembly GO:0070925 110 0.050
guanosine containing compound catabolic process GO:1901069 2 0.050
positive regulation of nucleotide catabolic process GO:0030813 1 0.049
cell projection morphogenesis GO:0048858 244 0.049
nucleocytoplasmic transport GO:0006913 4 0.048
regulation of protein targeting GO:1903533 2 0.047
establishment of localization GO:0051234 244 0.047
regulation of reproductive process GO:2000241 4 0.047
protein k48 linked ubiquitination GO:0070936 1 0.047
er nucleus signaling pathway GO:0006984 2 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.046
regulation of response to stimulus GO:0048583 269 0.046
protein complex localization GO:0031503 1 0.045
regulation of rna metabolic process GO:0051252 224 0.045
cell surface receptor signaling pathway GO:0007166 325 0.044
regulation of primary metabolic process GO:0080090 311 0.044
positive regulation of gtp catabolic process GO:0033126 1 0.044
nuclear import GO:0051170 3 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
transport GO:0006810 220 0.043
peptide transport GO:0015833 1 0.043
amino acid transport GO:0006865 2 0.043
gastrulation GO:0007369 208 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.040
regulation of transcription dna templated GO:0006355 213 0.040
regulation of carbohydrate metabolic process GO:0006109 4 0.040
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
single organism nuclear import GO:1902593 3 0.039
apoptotic process involved in development GO:1902742 2 0.039
positive regulation of gtpase activity GO:0043547 1 0.039
cell projection organization GO:0030030 284 0.039
protein targeting to nucleus GO:0044744 3 0.038
protein import GO:0017038 3 0.038
embryonic organ development GO:0048568 381 0.038
meiotic cell cycle process GO:1903046 3 0.038
regulation of protein import into nucleus GO:0042306 2 0.037
positive regulation of catabolic process GO:0009896 4 0.037
response to chemical GO:0042221 320 0.037
single organism transport GO:0044765 206 0.037
regulation of signal transduction GO:0009966 225 0.036
small molecule metabolic process GO:0044281 77 0.036
embryonic organ morphogenesis GO:0048562 274 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
guanosine containing compound metabolic process GO:1901068 4 0.036
skeletal system development GO:0001501 181 0.035
negative regulation of protein transport GO:0051224 3 0.035
nuclear transport GO:0051169 4 0.035
positive regulation of biological process GO:0048518 253 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
organelle transport along microtubule GO:0072384 1 0.035
lateral inhibition GO:0046331 1 0.033
single organism localization GO:1902578 225 0.032
mitochondrion organization GO:0007005 4 0.032
post golgi vesicle mediated transport GO:0006892 1 0.032
digestive system development GO:0055123 289 0.032
response to uv GO:0009411 3 0.031
rna metabolic process GO:0016070 219 0.031
peptide metabolic process GO:0006518 1 0.031
microtubule based movement GO:0007018 33 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
nucleic acid templated transcription GO:0097659 181 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
small gtpase mediated signal transduction GO:0007264 8 0.030
microtubule based process GO:0007017 60 0.030
regulation of nucleotide catabolic process GO:0030811 2 0.030
negative regulation of protein localization to nucleus GO:1900181 2 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
cellular modified amino acid metabolic process GO:0006575 3 0.029
lipid storage GO:0019915 1 0.029
cellular response to external stimulus GO:0071496 2 0.029
positive regulation of cellular process GO:0048522 201 0.029
organic acid metabolic process GO:0006082 31 0.029
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.028
cellular amide metabolic process GO:0043603 4 0.028
developmental programmed cell death GO:0010623 4 0.028
positive regulation of nucleoside metabolic process GO:0045979 1 0.028
dicarboxylic acid transport GO:0006835 1 0.028
neurotransmitter transport GO:0006836 2 0.028
regulation of protein localization to nucleus GO:1900180 2 0.028
centrosome duplication GO:0051298 1 0.028
cell motility GO:0048870 244 0.028
negative regulation of cytoplasmic transport GO:1903650 2 0.028
cellular component movement GO:0006928 335 0.028
digestive tract development GO:0048565 265 0.028
regulation of rho protein signal transduction GO:0035023 2 0.028
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
regulation of rna biosynthetic process GO:2001141 213 0.027
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.027
cellular response to starvation GO:0009267 1 0.027
mitotic dna integrity checkpoint GO:0044774 4 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
sensory organ development GO:0007423 393 0.027
biosynthetic process GO:0009058 294 0.026
chemosensory behavior GO:0007635 1 0.026
regionalization GO:0003002 274 0.026
digestive tract morphogenesis GO:0048546 231 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
gene expression GO:0010467 252 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.025
i kappab kinase nf kappab signaling GO:0007249 4 0.025
organelle fusion GO:0048284 3 0.025
regulation of cell communication GO:0010646 232 0.025
multicellular organism growth GO:0035264 4 0.025
maintenance of location GO:0051235 4 0.025
translational initiation GO:0006413 3 0.025
carbohydrate biosynthetic process GO:0016051 1 0.025
negative regulation of metabolic process GO:0009892 86 0.024
macromolecule modification GO:0043412 111 0.024
single organism organelle organization GO:1902589 199 0.024
cellular response to unfolded protein GO:0034620 2 0.024
regulation of organelle assembly GO:1902115 4 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
ras protein signal transduction GO:0007265 7 0.024
cellular response to chemical stimulus GO:0070887 157 0.023
cellular response to topologically incorrect protein GO:0035967 2 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
protein dephosphorylation GO:0006470 3 0.023
response to unfolded protein GO:0006986 2 0.023
response to alkaloid GO:0043279 2 0.023
cellular protein catabolic process GO:0044257 4 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
ribosomal small subunit biogenesis GO:0042274 2 0.023
regulation of localization GO:0032879 104 0.023
regulation of cellular metabolic process GO:0031323 320 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of metal ion transport GO:0010959 4 0.022
oxoacid metabolic process GO:0043436 31 0.022
negative regulation of intracellular transport GO:0032387 3 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
compound eye development GO:0048749 2 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
secondary metabolic process GO:0019748 3 0.022
meiosis i GO:0007127 1 0.021
negative regulation of kinase activity GO:0033673 4 0.021
membrane invagination GO:0010324 1 0.021
specification of symmetry GO:0009799 204 0.021
synaptic vesicle endocytosis GO:0048488 1 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
locomotion GO:0040011 313 0.021
cell part morphogenesis GO:0032990 246 0.020
negative regulation of gliogenesis GO:0014014 1 0.020
peptidyl serine modification GO:0018209 2 0.020
liver development GO:0001889 96 0.020
phagocytosis GO:0006909 3 0.020
positive regulation of secretion GO:0051047 1 0.020
negative regulation of reproductive process GO:2000242 3 0.020
organelle organization GO:0006996 227 0.020
negative regulation of intracellular protein transport GO:0090317 3 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.020
programmed cell death GO:0012501 119 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
macroautophagy GO:0016236 1 0.020
axonogenesis GO:0007409 152 0.019
regulation of biological quality GO:0065008 263 0.019
cell cycle process GO:0022402 53 0.019
regulation of gtpase activity GO:0043087 2 0.019
neuron differentiation GO:0030182 353 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
single organism membrane fusion GO:0044801 2 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
cytokinesis GO:0000910 3 0.019
stem cell proliferation GO:0072089 4 0.019
intracellular signal transduction GO:0035556 85 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
membrane fusion GO:0061025 2 0.019
skeletal system morphogenesis GO:0048705 102 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
vacuolar transport GO:0007034 2 0.019
regulation of protein catabolic process GO:0042176 1 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
meiotic chromosome segregation GO:0045132 3 0.019
hormone secretion GO:0046879 2 0.019
response to light stimulus GO:0009416 46 0.019
peptidyl serine phosphorylation GO:0018105 1 0.018
synaptic vesicle transport GO:0048489 1 0.018
homeostatic process GO:0042592 142 0.018
stem cell maintenance GO:0019827 4 0.018
cartilage development GO:0051216 96 0.018
establishment of localization in cell GO:0051649 77 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
synaptic vesicle recycling GO:0036465 1 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
determination of bilateral symmetry GO:0009855 204 0.018
sleep GO:0030431 1 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
regulation of signaling GO:0023051 235 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
apoptotic process GO:0006915 116 0.017
protein modification process GO:0036211 100 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
er to golgi vesicle mediated transport GO:0006888 1 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
embryonic skeletal system development GO:0048706 97 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
hormone transport GO:0009914 2 0.016
gland development GO:0048732 143 0.016
localization of cell GO:0051674 244 0.016
rna biosynthetic process GO:0032774 181 0.016
axon development GO:0061564 166 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of ras gtpase activity GO:0032318 2 0.016
negative regulation of cellular process GO:0048523 283 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.015
locomotor rhythm GO:0045475 3 0.015
regulation of response to oxidative stress GO:1902882 2 0.015
cellular component morphogenesis GO:0032989 336 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
cellular amine metabolic process GO:0044106 2 0.015
regulation of binding GO:0051098 3 0.015
nucleoside phosphate metabolic process GO:0006753 28 0.015
alcohol biosynthetic process GO:0046165 2 0.015
response to radiation GO:0009314 51 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
muscle structure development GO:0061061 196 0.015
cytoplasm organization GO:0007028 4 0.015
cellular ketone metabolic process GO:0042180 11 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
muscle cell differentiation GO:0042692 139 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
transmembrane transport GO:0055085 120 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
golgi vesicle transport GO:0048193 3 0.014
positive regulation of jak stat cascade GO:0046427 2 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
transcription dna templated GO:0006351 181 0.014
chordate embryonic development GO:0043009 271 0.014
positive regulation of cell cycle GO:0045787 3 0.014
neurotransmitter secretion GO:0007269 2 0.014
cellular localization GO:0051641 97 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
regulation of programmed cell death GO:0043067 101 0.014
cellular protein metabolic process GO:0044267 129 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
muscle tissue development GO:0060537 110 0.014
exocytosis GO:0006887 1 0.014
endosome to lysosome transport GO:0008333 1 0.014
cellular response to oxygen levels GO:0071453 1 0.014
hepaticobiliary system development GO:0061008 98 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
renal tubule morphogenesis GO:0061333 1 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
pole plasm assembly GO:0007315 4 0.013
amine metabolic process GO:0009308 2 0.013
cell morphogenesis GO:0000902 289 0.013
neuron projection development GO:0031175 180 0.013
single organism biosynthetic process GO:0044711 71 0.013
cell aging GO:0007569 2 0.013
positive regulation of signaling GO:0023056 56 0.013
germ line stem cell maintenance GO:0030718 2 0.013
neurological system process GO:0050877 62 0.013
energy reserve metabolic process GO:0006112 2 0.013
striated muscle cell differentiation GO:0051146 129 0.013
tissue remodeling GO:0048771 4 0.013
primary neural tube formation GO:0014020 1 0.013
synaptic vesicle localization GO:0097479 1 0.013
phagocytosis engulfment GO:0006911 1 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
camera type eye development GO:0043010 222 0.013
positive regulation of ras gtpase activity GO:0032320 1 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
rna localization GO:0006403 4 0.013
response to nutrient GO:0007584 3 0.013
regulation of dna replication GO:0006275 3 0.013
regulation of transporter activity GO:0032409 2 0.013
central nervous system development GO:0007417 387 0.012
system process GO:0003008 185 0.012
cellular response to stress GO:0033554 62 0.012
vasculature development GO:0001944 278 0.012
negative regulation of tor signaling GO:0032007 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
telomere maintenance GO:0000723 1 0.012
activation of mapk activity GO:0000187 3 0.012
response to organic substance GO:0010033 153 0.012
multi organism process GO:0051704 134 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
neuron projection morphogenesis GO:0048812 161 0.012
regulation of dendrite development GO:0050773 3 0.012
amide biosynthetic process GO:0043604 1 0.012
developmental cell growth GO:0048588 52 0.012
cellular macromolecule localization GO:0070727 21 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
ion homeostasis GO:0050801 41 0.012
regulation of tube size GO:0035150 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
negative regulation of multi organism process GO:0043901 3 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
heart morphogenesis GO:0003007 156 0.012
regulation of organ growth GO:0046620 3 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
response to hydrogen peroxide GO:0042542 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
iron ion homeostasis GO:0055072 4 0.011
single organism cellular localization GO:1902580 46 0.011
connective tissue development GO:0061448 99 0.011
phagosome maturation GO:0090382 1 0.011
growth GO:0040007 174 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
positive regulation of cell communication GO:0010647 56 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
axon cargo transport GO:0008088 2 0.011
sexual reproduction GO:0019953 36 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
death GO:0016265 121 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
organic substance transport GO:0071702 58 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
regulation of wound healing GO:0061041 2 0.011
blood vessel morphogenesis GO:0048514 216 0.011
cell cycle g1 s phase transition GO:0044843 1 0.010
protein secretion GO:0009306 1 0.010
actin filament based movement GO:0030048 1 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
ion transport GO:0006811 114 0.010
rho protein signal transduction GO:0007266 5 0.010
organic substance catabolic process GO:1901575 28 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
rna transport GO:0050658 2 0.010
leukocyte homeostasis GO:0001776 2 0.010
protein modification by small protein removal GO:0070646 1 0.010
nucleic acid metabolic process GO:0090304 244 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
regulation of blood vessel size GO:0050880 2 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
regulation of synapse assembly GO:0051963 3 0.010
regulation of jak stat cascade GO:0046425 3 0.010
regulation of developmental process GO:0050793 247 0.010
dna templated transcription elongation GO:0006354 3 0.010
centrosome localization GO:0051642 1 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
carbohydrate homeostasis GO:0033500 1 0.010

march6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.012