Danio rerio

41 known processes

marcksa

myristoylated alanine rich protein kinase C substrate a

(Aliases: zgc:109978)

marcksa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
zinc ion transmembrane transport GO:0071577 1 0.334
death GO:0016265 121 0.256
regulation of biosynthetic process GO:0009889 250 0.246
central nervous system development GO:0007417 387 0.234
negative regulation of ras protein signal transduction GO:0046580 1 0.231
cell projection organization GO:0030030 284 0.226
gene expression GO:0010467 252 0.220
heterocycle metabolic process GO:0046483 290 0.200
regulation of mrna processing GO:0050684 3 0.185
macromolecule biosynthetic process GO:0009059 227 0.176
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.172
nitrogen compound metabolic process GO:0006807 319 0.165
cellular biosynthetic process GO:0044249 286 0.156
negative regulation of biological process GO:0048519 304 0.154
cell part morphogenesis GO:0032990 246 0.146
regulation of nitrogen compound metabolic process GO:0051171 251 0.135
regulation of mrna splicing via spliceosome GO:0048024 3 0.129
cellular macromolecule metabolic process GO:0044260 391 0.128
cellular macromolecule biosynthetic process GO:0034645 224 0.127
organic substance biosynthetic process GO:1901576 289 0.125
nucleic acid templated transcription GO:0097659 181 0.121
microtubule organizing center organization GO:0031023 1 0.116
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.105
negative regulation of cellular process GO:0048523 283 0.103
regulation of nucleic acid templated transcription GO:1903506 213 0.097
regulation of rna metabolic process GO:0051252 224 0.095
cellular aromatic compound metabolic process GO:0006725 295 0.091
adult behavior GO:0030534 2 0.090
cellular nitrogen compound metabolic process GO:0034641 290 0.087
organic cyclic compound metabolic process GO:1901360 301 0.087
aromatic compound biosynthetic process GO:0019438 217 0.084
cellular component morphogenesis GO:0032989 336 0.084
cell morphogenesis involved in differentiation GO:0000904 195 0.080
sensory organ development GO:0007423 393 0.077
rna metabolic process GO:0016070 219 0.076
cell proliferation GO:0008283 80 0.076
regulation of cellular metabolic process GO:0031323 320 0.075
striated muscle tissue development GO:0014706 110 0.073
negative regulation of gene expression GO:0010629 65 0.071
protein acetylation GO:0006473 2 0.070
positive regulation of transport GO:0051050 2 0.067
regulation of transcription dna templated GO:0006355 213 0.067
nucleic acid metabolic process GO:0090304 244 0.067
transcription dna templated GO:0006351 181 0.066
establishment of localization GO:0051234 244 0.064
embryo development ending in birth or egg hatching GO:0009792 271 0.064
stem cell maintenance GO:0019827 4 0.063
rna biosynthetic process GO:0032774 181 0.059
cell morphogenesis GO:0000902 289 0.058
transport GO:0006810 220 0.057
positive regulation of translation GO:0045727 1 0.057
cell projection morphogenesis GO:0048858 244 0.056
maintenance of location GO:0051235 4 0.054
response to stress GO:0006950 263 0.052
ion transport GO:0006811 114 0.052
programmed cell death GO:0012501 119 0.052
organic cyclic compound biosynthetic process GO:1901362 223 0.052
negative regulation of rna splicing GO:0033119 1 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.050
optic nerve morphogenesis GO:0021631 6 0.048
regulation of gene expression GO:0010468 265 0.048
protein stabilization GO:0050821 2 0.048
growth GO:0040007 174 0.047
single organism transport GO:0044765 206 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.047
positive regulation of cytoskeleton organization GO:0051495 3 0.046
internal peptidyl lysine acetylation GO:0018393 2 0.045
biosynthetic process GO:0009058 294 0.045
nucleocytoplasmic transport GO:0006913 4 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.044
response to wounding GO:0009611 116 0.043
positive regulation of cell activation GO:0050867 1 0.042
cell volume homeostasis GO:0006884 1 0.042
intracellular signal transduction GO:0035556 85 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
apoptotic process GO:0006915 116 0.042
extrinsic apoptotic signaling pathway GO:0097191 3 0.041
cell cycle arrest GO:0007050 1 0.041
chordate embryonic development GO:0043009 271 0.040
protein modification process GO:0036211 100 0.040
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.039
lipid storage GO:0019915 1 0.039
homeostatic process GO:0042592 142 0.038
response to chemical GO:0042221 320 0.037
morphogenesis of an epithelium GO:0002009 333 0.037
cellular response to organic substance GO:0071310 105 0.036
neuron development GO:0048666 262 0.036
cell cycle GO:0007049 93 0.036
regulation of apoptotic process GO:0042981 98 0.035
nuclear export GO:0051168 1 0.035
protein acylation GO:0043543 3 0.034
regulation of microtubule cytoskeleton organization GO:0070507 3 0.034
gtp metabolic process GO:0046039 4 0.034
ras protein signal transduction GO:0007265 7 0.034
regulation of rna biosynthetic process GO:2001141 213 0.033
cellular component movement GO:0006928 335 0.033
regulation of primary metabolic process GO:0080090 311 0.033
digestive tract morphogenesis GO:0048546 231 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
immune system process GO:0002376 241 0.032
single organism localization GO:1902578 225 0.032
regulation of metabolic process GO:0019222 359 0.032
head development GO:0060322 303 0.031
cellular component assembly GO:0022607 170 0.031
regulation of cell communication GO:0010646 232 0.031
exocytosis GO:0006887 1 0.031
positive regulation of cellular process GO:0048522 201 0.031
g2 m transition of mitotic cell cycle GO:0000086 4 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.030
organelle organization GO:0006996 227 0.030
negative regulation of macromolecule metabolic process GO:0010605 76 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.030
reproduction GO:0000003 40 0.029
digestive tract development GO:0048565 265 0.029
positive regulation of secretion GO:0051047 1 0.029
regulation of wound healing GO:0061041 2 0.029
negative regulation of metabolic process GO:0009892 86 0.029
regulation of cellular response to oxidative stress GO:1900407 2 0.028
microtubule based process GO:0007017 60 0.028
cellular component biogenesis GO:0044085 178 0.028
wound healing GO:0042060 90 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.028
cell death GO:0008219 121 0.028
establishment of protein localization to organelle GO:0072594 4 0.027
epithelial cell morphogenesis GO:0003382 2 0.027
negative regulation of kinase activity GO:0033673 4 0.027
centrosome organization GO:0051297 1 0.026
signal transduction GO:0007165 455 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
larval development GO:0002164 2 0.026
organelle assembly GO:0070925 110 0.026
positive regulation of epithelial cell differentiation GO:0030858 2 0.026
protein metabolic process GO:0019538 183 0.025
regulation of protein complex assembly GO:0043254 3 0.025
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
vasculature development GO:0001944 278 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of signaling GO:0023051 235 0.025
peptidyl lysine acetylation GO:0018394 2 0.025
positive regulation of dna metabolic process GO:0051054 1 0.024
embryonic digestive tract development GO:0048566 4 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of dna templated transcription elongation GO:0032784 3 0.024
response to topologically incorrect protein GO:0035966 2 0.024
response to nutrient GO:0007584 3 0.024
nuclear transport GO:0051169 4 0.024
cell migration GO:0016477 237 0.024
somite development GO:0061053 96 0.024
centrosome cycle GO:0007098 1 0.024
positive regulation of gene expression GO:0010628 71 0.024
positive regulation of carbohydrate metabolic process GO:0045913 1 0.024
regulation of carbohydrate metabolic process GO:0006109 4 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
regulation of establishment of planar polarity GO:0090175 4 0.023
regionalization GO:0003002 274 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
nucleic acid transport GO:0050657 2 0.023
dna catabolic process GO:0006308 1 0.023
optic nerve development GO:0021554 15 0.023
regulation of cell proliferation GO:0042127 37 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
positive regulation of biosynthetic process GO:0009891 68 0.022
muscle tissue development GO:0060537 110 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
cell substrate adhesion GO:0031589 4 0.022
cellular protein metabolic process GO:0044267 129 0.022
single organism organelle organization GO:1902589 199 0.022
alternative mrna splicing via spliceosome GO:0000380 1 0.022
neuron differentiation GO:0030182 353 0.022
negative regulation of mrna processing GO:0050686 1 0.021
muscle structure development GO:0061061 196 0.021
transmembrane transport GO:0055085 120 0.021
epithelial cell development GO:0002064 42 0.021
rna stabilization GO:0043489 4 0.021
centrosome duplication GO:0051298 1 0.021
cation transport GO:0006812 81 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
epithelial cell morphogenesis involved in gastrulation GO:0003381 1 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
stem cell differentiation GO:0048863 117 0.020
camera type eye development GO:0043010 222 0.020
response to organic substance GO:0010033 153 0.020
cranial nerve development GO:0021545 42 0.020
eye development GO:0001654 277 0.020
mrna metabolic process GO:0016071 20 0.020
cellular response to dsrna GO:0071359 1 0.020
regulation of oxidative stress induced cell death GO:1903201 2 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
macromolecule modification GO:0043412 111 0.019
establishment of rna localization GO:0051236 3 0.019
amine metabolic process GO:0009308 2 0.019
tube morphogenesis GO:0035239 349 0.019
striated muscle cell development GO:0055002 108 0.018
regulation of response to stimulus GO:0048583 269 0.018
metal ion transport GO:0030001 58 0.018
negative regulation of cell communication GO:0010648 96 0.018
cell cycle g2 m phase transition GO:0044839 4 0.018
neuron projection morphogenesis GO:0048812 161 0.018
embryonic organ development GO:0048568 381 0.018
regulation of signal transduction GO:0009966 225 0.018
regulation of organelle assembly GO:1902115 4 0.018
water transport GO:0006833 15 0.018
convergent extension involved in gastrulation GO:0060027 71 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
determination of bilateral symmetry GO:0009855 204 0.018
blood vessel morphogenesis GO:0048514 216 0.017
neuron projection development GO:0031175 180 0.017
spermatid differentiation GO:0048515 2 0.017
response to external stimulus GO:0009605 264 0.017
phagocytosis GO:0006909 3 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.017
hemopoiesis GO:0030097 183 0.017
multicellular organism growth GO:0035264 4 0.017
response to vitamin GO:0033273 3 0.017
microtubule cytoskeleton organization GO:0000226 33 0.017
negative regulation of signal transduction GO:0009968 94 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
sequestering of metal ion GO:0051238 3 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
anterior posterior pattern specification GO:0009952 152 0.017
camera type eye morphogenesis GO:0048593 108 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
negative regulation of developmental process GO:0051093 65 0.016
autophagy GO:0006914 4 0.016
rna transport GO:0050658 2 0.016
locomotion GO:0040011 313 0.016
rna processing GO:0006396 25 0.016
epithelial cell differentiation GO:0030855 116 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of circadian rhythm GO:0042752 4 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.016
translation GO:0006412 5 0.016
regulation of localization GO:0032879 104 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
secondary metabolic process GO:0019748 3 0.015
rna export from nucleus GO:0006405 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
aging GO:0007568 2 0.015
cellular ketone metabolic process GO:0042180 11 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of developmental process GO:0050793 247 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
regulation of cell death GO:0010941 103 0.015
positive regulation of exocytosis GO:0045921 1 0.015
regulation of rna splicing GO:0043484 8 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
meiotic nuclear division GO:0007126 4 0.015
positive regulation of catabolic process GO:0009896 4 0.015
digestive system development GO:0055123 289 0.015
response to organic cyclic compound GO:0014070 51 0.015
oxoacid metabolic process GO:0043436 31 0.015
muscle cell development GO:0055001 115 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
cell matrix adhesion GO:0007160 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
translational initiation GO:0006413 3 0.014
regulation of translational initiation GO:0006446 1 0.014
angiogenesis GO:0001525 158 0.014
regulation of programmed cell death GO:0043067 101 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
female gonad development GO:0008585 4 0.014
melanin metabolic process GO:0006582 2 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
system process GO:0003008 185 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of organ morphogenesis GO:2000027 35 0.014
spermatid development GO:0007286 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
protein localization GO:0008104 40 0.013
cilium morphogenesis GO:0060271 85 0.013
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.013
muscle organ development GO:0007517 101 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
positive regulation of reproductive process GO:2000243 2 0.013
regulation of cellular component organization GO:0051128 86 0.013
cranial nerve morphogenesis GO:0021602 15 0.013
cell aging GO:0007569 2 0.013
divalent inorganic cation homeostasis GO:0072507 22 0.013
regulation of protein transport GO:0051223 3 0.013
negative regulation of biosynthetic process GO:0009890 55 0.012
negative regulation of axon regeneration GO:0048681 4 0.012
regulation of epidermis development GO:0045682 2 0.012
somatic cell dna recombination GO:0016444 1 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
single organism metabolic process GO:0044710 217 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
mitotic cell cycle GO:0000278 64 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of gene expression epigenetic GO:0040029 11 0.012
blood vessel development GO:0001568 246 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
female sex differentiation GO:0046660 4 0.012
cell cycle process GO:0022402 53 0.012
ion transmembrane transport GO:0034220 91 0.012
protein secretion GO:0009306 1 0.012
mitotic cell cycle process GO:1903047 48 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
axonogenesis GO:0007409 152 0.012
spindle assembly GO:0051225 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
negative regulation of neuron projection regeneration GO:0070571 4 0.012
regulation of metal ion transport GO:0010959 4 0.012
protein complex localization GO:0031503 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
muscle cell differentiation GO:0042692 139 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.011
primary neural tube formation GO:0014020 1 0.011
regulation of cell activation GO:0050865 1 0.011
cellular homeostasis GO:0019725 26 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
glucose homeostasis GO:0042593 1 0.011
adherens junction organization GO:0034332 4 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of multi organism process GO:0043902 3 0.011
regulation of neurological system process GO:0031644 2 0.011
polarized epithelial cell differentiation GO:0030859 4 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
regulation of embryonic development GO:0045995 47 0.011
behavior GO:0007610 74 0.011
protein localization to nucleus GO:0034504 3 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
actin filament polymerization GO:0030041 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
adherens junction assembly GO:0034333 1 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
cellular localization GO:0051641 97 0.011
sensory system development GO:0048880 76 0.011
nucleobase containing compound transport GO:0015931 2 0.011
embryonic heart tube development GO:0035050 133 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
organic cyclic compound catabolic process GO:1901361 15 0.010
cytoskeleton organization GO:0007010 96 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regeneration GO:0031099 91 0.010
tube closure GO:0060606 1 0.010
nerve development GO:0021675 45 0.010
actin filament based process GO:0030029 64 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
cellular response to external stimulus GO:0071496 2 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
immune system development GO:0002520 191 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
mechanosensory behavior GO:0007638 2 0.010

marcksa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.085
disease of cellular proliferation DOID:14566 0 0.085
organ system cancer DOID:0050686 0 0.085
physical disorder DOID:0080015 0 0.046
disease of anatomical entity DOID:7 0 0.038
congenital nervous system abnormality DOID:2490 0 0.023
nervous system disease DOID:863 0 0.015