Danio rerio

63 known processes

marcksb

myristoylated alanine rich protein kinase C substrate b

(Aliases: macs,wu:fc44a10,wu:fc19b04,MGC110235,marcks,wu:fb92d04,wu:fb55c06,zgc:110235)

marcksb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 303 0.604
cellular macromolecule biosynthetic process GO:0034645 224 0.556
regulation of protein complex assembly GO:0043254 3 0.481
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.450
dna modification GO:0006304 8 0.446
neuron projection development GO:0031175 180 0.407
heterocycle metabolic process GO:0046483 290 0.398
regulation of nucleic acid templated transcription GO:1903506 213 0.382
regulation of gene expression GO:0010468 265 0.329
transcription dna templated GO:0006351 181 0.323
organic substance biosynthetic process GO:1901576 289 0.313
cellular nitrogen compound biosynthetic process GO:0044271 218 0.297
regulation of nitrogen compound metabolic process GO:0051171 251 0.263
regulation of transcription dna templated GO:0006355 213 0.256
camera type eye morphogenesis GO:0048593 108 0.244
macromolecule biosynthetic process GO:0009059 227 0.239
negative regulation of biological process GO:0048519 304 0.230
Fly
cytokinesis GO:0000910 3 0.222
regulation of biosynthetic process GO:0009889 250 0.218
regulation of cellular biosynthetic process GO:0031326 245 0.218
cell morphogenesis involved in differentiation GO:0000904 195 0.216
nuclear envelope organization GO:0006998 2 0.210
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.205
cell morphogenesis GO:0000902 289 0.203
rna biosynthetic process GO:0032774 181 0.203
eye development GO:0001654 277 0.201
sensory organ morphogenesis GO:0090596 200 0.193
cellular component assembly GO:0022607 170 0.187
cellular aromatic compound metabolic process GO:0006725 295 0.186
nucleic acid metabolic process GO:0090304 244 0.175
camera type eye development GO:0043010 222 0.170
negative regulation of cellular process GO:0048523 283 0.164
Fly
regulation of multicellular organismal process GO:0051239 277 0.164
Fly
cell projection organization GO:0030030 284 0.159
heterocycle biosynthetic process GO:0018130 215 0.150
aromatic compound biosynthetic process GO:0019438 217 0.148
regulation of rna biosynthetic process GO:2001141 213 0.147
rna metabolic process GO:0016070 219 0.144
dna methylation or demethylation GO:0044728 8 0.139
single organism localization GO:1902578 225 0.138
central nervous system development GO:0007417 387 0.136
dna alkylation GO:0006305 8 0.134
rna stabilization GO:0043489 4 0.133
neuron development GO:0048666 262 0.133
positive regulation of cellular process GO:0048522 201 0.132
macromolecular complex subunit organization GO:0043933 74 0.126
regulation of macromolecule metabolic process GO:0060255 317 0.122
striated muscle tissue development GO:0014706 110 0.122
negative regulation of gene expression GO:0010629 65 0.118
negative regulation of nucleic acid templated transcription GO:1903507 45 0.117
protein complex disassembly GO:0043241 1 0.116
cellular macromolecule metabolic process GO:0044260 391 0.115
nucleobase containing compound biosynthetic process GO:0034654 205 0.113
organic cyclic compound metabolic process GO:1901360 301 0.113
dna methylation GO:0006306 8 0.112
single organism organelle organization GO:1902589 199 0.110
regulation of macromolecule biosynthetic process GO:0010556 225 0.106
negative regulation of rna metabolic process GO:0051253 48 0.100
regulation of rna metabolic process GO:0051252 224 0.097
cellular component morphogenesis GO:0032989 336 0.096
maintenance of location GO:0051235 4 0.095
regulation of cellular metabolic process GO:0031323 320 0.094
centrosome cycle GO:0007098 1 0.093
nucleobase containing compound metabolic process GO:0006139 274 0.091
heart morphogenesis GO:0003007 156 0.089
neuron differentiation GO:0030182 353 0.088
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.088
mitotic cell cycle embryonic GO:0045448 2 0.087
biosynthetic process GO:0009058 294 0.086
cell part morphogenesis GO:0032990 246 0.086
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.086
positive regulation of chromosome segregation GO:0051984 1 0.085
negative regulation of ras protein signal transduction GO:0046580 1 0.085
Fly
retina development in camera type eye GO:0060041 146 0.084
nucleic acid templated transcription GO:0097659 181 0.084
generation of neurons GO:0048699 385 0.083
negative regulation of cellular biosynthetic process GO:0031327 55 0.083
skeletal muscle organ development GO:0060538 78 0.081
muscle tissue development GO:0060537 110 0.081
methylation GO:0032259 22 0.081
chromatin modification GO:0016568 21 0.079
cell projection morphogenesis GO:0048858 244 0.078
negative regulation of transcription dna templated GO:0045892 45 0.078
negative regulation of cellular component organization GO:0051129 16 0.077
digestive system development GO:0055123 289 0.077
regulation of gene expression epigenetic GO:0040029 11 0.076
regulation of cytoskeleton organization GO:0051493 11 0.074
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.074
transcription from rna polymerase ii promoter GO:0006366 80 0.074
regeneration GO:0031099 91 0.073
positive regulation of transport GO:0051050 2 0.072
protein complex subunit organization GO:0071822 46 0.070
cellular component disassembly GO:0022411 1 0.068
axon development GO:0061564 166 0.068
negative regulation of biosynthetic process GO:0009890 55 0.067
protein complex localization GO:0031503 1 0.065
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.064
axonogenesis GO:0007409 152 0.064
cellular component biogenesis GO:0044085 178 0.064
tube morphogenesis GO:0035239 349 0.063
synaptic growth at neuromuscular junction GO:0051124 2 0.062
positive regulation of cellular component biogenesis GO:0044089 3 0.060
positive regulation of gene expression GO:0010628 71 0.057
cellular biosynthetic process GO:0044249 286 0.057
microtubule organizing center organization GO:0031023 1 0.056
peptidyl lysine dimethylation GO:0018027 1 0.055
positive regulation of exocytosis GO:0045921 1 0.055
protein acetylation GO:0006473 2 0.054
negative regulation of cellular metabolic process GO:0031324 77 0.054
embryonic heart tube development GO:0035050 133 0.053
negative regulation of macromolecule metabolic process GO:0010605 76 0.053
retina morphogenesis in camera type eye GO:0060042 79 0.053
regulation of developmental process GO:0050793 247 0.052
Fly
cellular component movement GO:0006928 335 0.051
organelle organization GO:0006996 227 0.051
histone h3 k9 methylation GO:0051567 5 0.051
chromosome organization GO:0051276 31 0.051
regulation of microtubule cytoskeleton organization GO:0070507 3 0.050
regulation of anterior head development GO:2000742 2 0.050
wound healing GO:0042060 90 0.049
regulation of apoptotic process GO:0042981 98 0.046
histone modification GO:0016570 20 0.046
regulation of synapse assembly GO:0051963 3 0.046
regionalization GO:0003002 274 0.045
mitotic cell cycle GO:0000278 64 0.045
neuroblast proliferation GO:0007405 2 0.044
negative regulation of metabolic process GO:0009892 86 0.042
gene silencing GO:0016458 4 0.041
determination of left right symmetry GO:0007368 179 0.041
neural tube patterning GO:0021532 33 0.040
positive regulation of biological process GO:0048518 253 0.040
digestive tract morphogenesis GO:0048546 231 0.040
skeletal muscle tissue development GO:0007519 67 0.040
muscle organ development GO:0007517 101 0.039
protein metabolic process GO:0019538 183 0.039
positive regulation of dna metabolic process GO:0051054 1 0.038
muscle structure development GO:0061061 196 0.038
gene expression GO:0010467 252 0.038
regulation of synapse organization GO:0050807 3 0.037
regulation of cellular component biogenesis GO:0044087 12 0.037
microtubule cytoskeleton organization GO:0000226 33 0.036
growth GO:0040007 174 0.036
histone h3 k9 modification GO:0061647 5 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.035
larval development GO:0002164 2 0.035
regulation of cell communication GO:0010646 232 0.035
Fly
positive regulation of biosynthetic process GO:0009891 68 0.035
macromolecular complex assembly GO:0065003 35 0.035
regulation of stem cell proliferation GO:0072091 2 0.035
negative regulation of cell communication GO:0010648 96 0.034
Fly
regulation of neurogenesis GO:0050767 87 0.033
cellular protein metabolic process GO:0044267 129 0.032
regulation of stem cell differentiation GO:2000736 4 0.032
sensory organ development GO:0007423 393 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
signal transduction GO:0007165 455 0.031
Fly
negative regulation of chromosome organization GO:2001251 1 0.031
tissue regeneration GO:0042246 74 0.031
negative regulation of rna biosynthetic process GO:1902679 45 0.029
regulation of primary metabolic process GO:0080090 311 0.029
macromolecule methylation GO:0043414 19 0.029
protein acylation GO:0043543 3 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of mrna stability GO:0043488 4 0.028
mesenchymal cell differentiation GO:0048762 87 0.028
immune system process GO:0002376 241 0.028
anterior head development GO:0097065 2 0.028
g2 m transition of mitotic cell cycle GO:0000086 4 0.027
adult behavior GO:0030534 2 0.026
Fly
posttranscriptional regulation of gene expression GO:0010608 14 0.026
regulation of epithelial to mesenchymal transition GO:0010717 3 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
mrna stabilization GO:0048255 4 0.025
multi organism process GO:0051704 134 0.025
embryonic organ development GO:0048568 381 0.025
anterior posterior pattern specification GO:0009952 152 0.025
transport GO:0006810 220 0.025
dna templated transcription initiation GO:0006352 1 0.025
neuron projection morphogenesis GO:0048812 161 0.025
regulation of chromosome segregation GO:0051983 1 0.025
regulation of metabolic process GO:0019222 359 0.024
regulation of cell differentiation GO:0045595 142 0.024
cytoskeleton organization GO:0007010 96 0.023
regulation of neuron projection development GO:0010975 40 0.023
centrosome organization GO:0051297 1 0.023
muscle cell differentiation GO:0042692 139 0.023
developmental growth GO:0048589 166 0.023
positive regulation of cytoskeleton organization GO:0051495 3 0.022
determination of bilateral symmetry GO:0009855 204 0.022
regulation of signal transduction GO:0009966 225 0.022
Fly
peptidyl lysine acetylation GO:0018394 2 0.022
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
establishment of localization GO:0051234 244 0.021
single organism transport GO:0044765 206 0.021
fin regeneration GO:0031101 51 0.021
hemopoiesis GO:0030097 183 0.021
peptidyl lysine methylation GO:0018022 3 0.021
regulation of dna methylation GO:0044030 5 0.020
ameboidal type cell migration GO:0001667 143 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
cytokinetic process GO:0032506 2 0.020
response to organic substance GO:0010033 153 0.020
Fly
positive regulation of transcription dna templated GO:0045893 57 0.020
specification of symmetry GO:0009799 204 0.019
stem cell maintenance GO:0019827 4 0.019
multicellular organism growth GO:0035264 4 0.019
regulation of localization GO:0032879 104 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
lateral inhibition GO:0046331 1 0.019
heart development GO:0007507 313 0.019
sequestering of metal ion GO:0051238 3 0.018
cell death GO:0008219 121 0.018
Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.018
protein methylation GO:0006479 13 0.018
nucleobase containing compound transport GO:0015931 2 0.018
regulation of wound healing GO:0061041 2 0.018
centrosome duplication GO:0051298 1 0.018
regulation of growth rate GO:0040009 1 0.017
protein localization to nucleus GO:0034504 3 0.017
appendage morphogenesis GO:0035107 56 0.017
retinoic acid metabolic process GO:0042573 9 0.017
organelle assembly GO:0070925 110 0.017
cell proliferation GO:0008283 80 0.017
regulation of wnt signaling pathway GO:0030111 53 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
nerve development GO:0021675 45 0.017
muscle cell development GO:0055001 115 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
posttranscriptional gene silencing by rna GO:0035194 3 0.016
positive regulation of translation GO:0045727 1 0.016
energy reserve metabolic process GO:0006112 2 0.016
spermatid differentiation GO:0048515 2 0.016
regulation of histone h3 k9 methylation GO:0051570 2 0.016
modification of morphology or physiology of other organism GO:0035821 4 0.016
protein sumoylation GO:0016925 2 0.016
cilium morphogenesis GO:0060271 85 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
dna metabolic process GO:0006259 27 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
spermatid development GO:0007286 2 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
cellular macromolecular complex assembly GO:0034622 24 0.015
embryonic skeletal joint development GO:0072498 3 0.015
histone methylation GO:0016571 13 0.015
negative regulation of signal transduction GO:0009968 94 0.015
Fly
negative regulation of neuron projection regeneration GO:0070571 4 0.015
regulation of growth GO:0040008 42 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
protein alkylation GO:0008213 13 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regulation of ion transport GO:0043269 22 0.014
cell aging GO:0007569 2 0.014
covalent chromatin modification GO:0016569 20 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
macromolecular complex disassembly GO:0032984 1 0.014
epithelial cell development GO:0002064 42 0.014
digestive tract development GO:0048565 265 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
protein complex assembly GO:0006461 30 0.014
oxoacid metabolic process GO:0043436 31 0.014
mitotic cytokinesis GO:0000281 3 0.014
exocytosis GO:0006887 1 0.014
cell death in response to oxidative stress GO:0036473 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
translational initiation GO:0006413 3 0.013
actin filament based process GO:0030029 64 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
microtubule based process GO:0007017 60 0.013
mitotic cell cycle process GO:1903047 48 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
membrane organization GO:0061024 21 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
Fly
positive regulation of reproductive process GO:2000243 2 0.012
stem cell differentiation GO:0048863 117 0.012
regulation of dna metabolic process GO:0051052 11 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
endodermal cell fate determination GO:0007493 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
convergent extension GO:0060026 118 0.012
response to chemical GO:0042221 320 0.012
Fly
nucleocytoplasmic transport GO:0006913 4 0.012
negative regulation of axon regeneration GO:0048681 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
rna transport GO:0050658 2 0.012
midbrain development GO:0030901 28 0.012
wnt signaling pathway GO:0016055 80 0.012
sensory perception of light stimulus GO:0050953 19 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
establishment of organelle localization GO:0051656 45 0.011
response to wounding GO:0009611 116 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
cellular nitrogen compound catabolic process GO:0044270 15 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
negative regulation of chromatin modification GO:1903309 1 0.011
regulation of nervous system development GO:0051960 90 0.011
cation homeostasis GO:0055080 33 0.011
chordate embryonic development GO:0043009 271 0.011
mitotic nuclear division GO:0007067 18 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of cell death GO:0010941 103 0.011
axon guidance GO:0007411 86 0.011
ion transport GO:0006811 114 0.010
stem cell proliferation GO:0072089 4 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
establishment of blood brain barrier GO:0060856 2 0.010
atp catabolic process GO:0006200 4 0.010
stem cell development GO:0048864 82 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.010
3 utr mediated mrna stabilization GO:0070935 3 0.010
organelle localization GO:0051640 49 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of embryonic development GO:0045995 47 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
dna catabolic process GO:0006308 1 0.010
vasculature development GO:0001944 278 0.010
telomere organization GO:0032200 1 0.010
protein modification process GO:0036211 100 0.010

marcksb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.025
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.015
organ system cancer DOID:0050686 0 0.012
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
colorectal cancer DOID:9256 0 0.011