Danio rerio

0 known processes

mat1a

methionine adenosyltransferase I, alpha

(Aliases: wu:fi35e01,zgc:55442)

mat1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 3 0.250
multicellular organism growth GO:0035264 4 0.206
Worm
cellular amino acid biosynthetic process GO:0008652 2 0.188
single organism localization GO:1902578 225 0.166
Worm
single organism metabolic process GO:0044710 217 0.138
Worm
small molecule metabolic process GO:0044281 77 0.136
heart development GO:0007507 313 0.130
Zebrafish
intestinal cholesterol absorption GO:0030299 2 0.116
embryo development ending in birth or egg hatching GO:0009792 271 0.116
Worm
regulation of multicellular organism growth GO:0040014 4 0.110
Worm
carboxylic acid metabolic process GO:0019752 22 0.110
response to chemical GO:0042221 320 0.103
single organism transport GO:0044765 206 0.097
Worm
chordate embryonic development GO:0043009 271 0.097
alcohol biosynthetic process GO:0046165 2 0.096
organonitrogen compound metabolic process GO:1901564 74 0.091
maintenance of location GO:0051235 4 0.086
Worm
organic anion transport GO:0015711 15 0.085
oxoacid metabolic process GO:0043436 31 0.079
organonitrogen compound biosynthetic process GO:1901566 47 0.078
response to external stimulus GO:0009605 264 0.077
larval development GO:0002164 2 0.070
Worm
aging GO:0007568 2 0.070
Worm
nitrogen compound metabolic process GO:0006807 319 0.069
cellular amino acid metabolic process GO:0006520 7 0.067
cellular carbohydrate metabolic process GO:0044262 4 0.067
lipid metabolic process GO:0006629 52 0.067
Worm
negative regulation of cellular process GO:0048523 283 0.066
regulation of primary metabolic process GO:0080090 311 0.066
protein metabolic process GO:0019538 183 0.065
Worm
regulation of synapse assembly GO:0051963 3 0.065
cellular biosynthetic process GO:0044249 286 0.063
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.055
embryonic organ development GO:0048568 381 0.055
organic acid metabolic process GO:0006082 31 0.053
system process GO:0003008 185 0.052
ion transport GO:0006811 114 0.052
amine metabolic process GO:0009308 2 0.051
cellular amine metabolic process GO:0044106 2 0.050
organic substance biosynthetic process GO:1901576 289 0.048
Worm
neuron development GO:0048666 262 0.047
cellular response to steroid hormone stimulus GO:0071383 31 0.047
regulation of response to stimulus GO:0048583 269 0.047
lipid storage GO:0019915 1 0.046
Worm
regulation of biological quality GO:0065008 263 0.045
Worm
response to organic substance GO:0010033 153 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
single organism biosynthetic process GO:0044711 71 0.044
regulation of multicellular organismal process GO:0051239 277 0.044
Worm
energy reserve metabolic process GO:0006112 2 0.043
specification of symmetry GO:0009799 204 0.042
striated muscle cell development GO:0055002 108 0.041
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.041
cellular modified amino acid metabolic process GO:0006575 3 0.040
localization of cell GO:0051674 244 0.040
regulation of signaling GO:0023051 235 0.040
developmental growth GO:0048589 166 0.040
Worm
embryonic organ morphogenesis GO:0048562 274 0.038
heterocycle metabolic process GO:0046483 290 0.038
carboxylic acid catabolic process GO:0046395 3 0.037
biosynthetic process GO:0009058 294 0.037
Worm
carboxylic acid biosynthetic process GO:0046394 12 0.036
cellular ketone metabolic process GO:0042180 11 0.035
response to glucose GO:0009749 3 0.035
anion transport GO:0006820 38 0.034
central nervous system development GO:0007417 387 0.034
neuron differentiation GO:0030182 353 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
Worm
positive regulation of cell adhesion GO:0045785 1 0.033
dicarboxylic acid metabolic process GO:0043648 1 0.032
establishment of localization GO:0051234 244 0.032
Worm
regulation of developmental process GO:0050793 247 0.031
Worm
protein localization to plasma membrane GO:0072659 1 0.031
cellular response to organic cyclic compound GO:0071407 38 0.031
cell projection morphogenesis GO:0048858 244 0.030
adult behavior GO:0030534 2 0.030
positive regulation of catabolic process GO:0009896 4 0.030
cell projection organization GO:0030030 284 0.030
intestinal absorption GO:0050892 2 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
transport GO:0006810 220 0.028
Worm
determination of heart left right asymmetry GO:0061371 117 0.028
generation of neurons GO:0048699 385 0.028
tube morphogenesis GO:0035239 349 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
Worm
regulation of synapse organization GO:0050807 3 0.027
regulation of sodium ion transport GO:0002028 2 0.027
cartilage development GO:0051216 96 0.026
cellular lipid catabolic process GO:0044242 3 0.026
insulin like growth factor receptor signaling pathway GO:0048009 4 0.025
signal transduction GO:0007165 455 0.025
small molecule catabolic process GO:0044282 3 0.025
cellular lipid metabolic process GO:0044255 36 0.025
organelle organization GO:0006996 227 0.025
cellular response to external stimulus GO:0071496 2 0.025
phosphate containing compound metabolic process GO:0006796 108 0.024
multicellular organismal response to stress GO:0033555 2 0.024
small molecule biosynthetic process GO:0044283 16 0.024
positive regulation of gtp catabolic process GO:0033126 1 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
cellular response to estrogen stimulus GO:0071391 24 0.024
cell part morphogenesis GO:0032990 246 0.024
cellular response to lipid GO:0071396 39 0.024
regulation of cell communication GO:0010646 232 0.023
cognition GO:0050890 1 0.023
regulation of localization GO:0032879 104 0.023
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.022
response to endogenous stimulus GO:0009719 83 0.022
lipid digestion GO:0044241 3 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
organic acid biosynthetic process GO:0016053 12 0.022
regulation of endothelial cell proliferation GO:0001936 1 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
negative regulation of biological process GO:0048519 304 0.022
Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.022
determination of bilateral symmetry GO:0009855 204 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
post embryonic organ development GO:0048569 4 0.021
Worm
morphogenesis of an epithelium GO:0002009 333 0.020
organic acid catabolic process GO:0016054 3 0.020
branched chain amino acid metabolic process GO:0009081 1 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
stem cell maintenance GO:0019827 4 0.020
response to steroid hormone GO:0048545 35 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
cellular localization GO:0051641 97 0.019
Worm
phagocytosis GO:0006909 3 0.019
cell substrate adhesion GO:0031589 4 0.019
hormone metabolic process GO:0042445 19 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
pyrimidine containing compound metabolic process GO:0072527 3 0.019
head development GO:0060322 303 0.019
cellular response to organic substance GO:0071310 105 0.019
macromolecule localization GO:0033036 54 0.018
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.018
camera type eye development GO:0043010 222 0.018
organophosphate biosynthetic process GO:0090407 23 0.017
skeletal system development GO:0001501 181 0.017
determination of left right symmetry GO:0007368 179 0.017
striated muscle cell differentiation GO:0051146 129 0.017
Zebrafish
cell matrix adhesion GO:0007160 4 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
response to vitamin GO:0033273 3 0.016
immune system process GO:0002376 241 0.016
cell morphogenesis GO:0000902 289 0.016
brain development GO:0007420 293 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
embryonic heart tube development GO:0035050 133 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
response to estrogen GO:0043627 27 0.016
cell surface receptor signaling pathway GO:0007166 325 0.015
cellular hormone metabolic process GO:0034754 19 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
regulation of gene expression GO:0010468 265 0.015
Worm
skeletal system morphogenesis GO:0048705 102 0.015
muscle cell development GO:0055001 115 0.015
Zebrafish
embryonic skeletal system development GO:0048706 97 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
nucleic acid metabolic process GO:0090304 244 0.015
cellular component movement GO:0006928 335 0.015
zymogen activation GO:0031638 3 0.015
cell death GO:0008219 121 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
fatty acid transport GO:0015908 1 0.014
regulation of lipid transport GO:0032368 4 0.014
regionalization GO:0003002 274 0.014
response to hormone GO:0009725 48 0.014
locomotion GO:0040011 313 0.014
Worm
response to nutrient GO:0007584 3 0.014
response to lipid GO:0033993 60 0.014
regulation of signal transduction GO:0009966 225 0.014
single organism organelle organization GO:1902589 199 0.014
response to carbohydrate GO:0009743 3 0.014
defense response to fungus GO:0050832 2 0.013
peptide transport GO:0015833 1 0.013
eye development GO:0001654 277 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
long chain fatty acid transport GO:0015909 1 0.013
gtp catabolic process GO:0006184 2 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
Worm
sensory organ development GO:0007423 393 0.013
neuron projection morphogenesis GO:0048812 161 0.013
phosphorus metabolic process GO:0006793 109 0.013
blood coagulation fibrin clot formation GO:0072378 3 0.013
wound healing GO:0042060 90 0.013
negative regulation of dna replication GO:0008156 2 0.013
blood vessel development GO:0001568 246 0.013
growth GO:0040007 174 0.013
Worm
glucose homeostasis GO:0042593 1 0.013
astrocyte differentiation GO:0048708 1 0.013
melanin metabolic process GO:0006582 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
positive regulation of transport GO:0051050 2 0.013
regulation of sterol transport GO:0032371 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
regulation of dendrite development GO:0050773 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
lipid homeostasis GO:0055088 3 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
organic hydroxy compound transport GO:0015850 14 0.012
sensory organ morphogenesis GO:0090596 200 0.012
retina development in camera type eye GO:0060041 146 0.012
meiotic nuclear division GO:0007126 4 0.012
glial cell migration GO:0008347 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
response to corticosteroid GO:0031960 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
Worm
response to oxygen containing compound GO:1901700 55 0.012
phenol containing compound biosynthetic process GO:0046189 4 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
organic hydroxy compound biosynthetic process GO:1901617 6 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
negative regulation of signaling GO:0023057 96 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of metabolic process GO:0019222 359 0.012
Worm
cellular amide metabolic process GO:0043603 4 0.012
response to monosaccharide GO:0034284 3 0.012
cellular response to endogenous stimulus GO:0071495 68 0.011
s adenosylmethionine metabolic process GO:0046500 1 0.011
axon development GO:0061564 166 0.011
taxis GO:0042330 109 0.011
antimicrobial humoral response GO:0019730 2 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
multi organism process GO:0051704 134 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of reproductive process GO:2000241 4 0.011
gastrulation GO:0007369 208 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
septum transversum development GO:0003343 4 0.011
response to organic cyclic compound GO:0014070 51 0.011
response to hexose GO:0009746 3 0.011
oocyte maturation GO:0001556 4 0.011
regulation of growth GO:0040008 42 0.011
Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
gene expression GO:0010467 252 0.011
Worm
ribonucleoside biosynthetic process GO:0042455 2 0.011
positive regulation of biological process GO:0048518 253 0.011
Worm
positive regulation of metabolic process GO:0009893 108 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
catechol containing compound biosynthetic process GO:0009713 2 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.010
membrane invagination GO:0010324 1 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
cellular protein metabolic process GO:0044267 129 0.010
Worm
regeneration GO:0031099 91 0.010
negative regulation of defense response GO:0031348 2 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
secondary metabolic process GO:0019748 3 0.010
monocarboxylic acid catabolic process GO:0072329 3 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010

mat1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.022
lipid metabolism disorder DOID:3146 0 0.016
bone marrow disease DOID:4961 0 0.013
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
hematopoietic system disease DOID:74 0 0.013
amyloidosis DOID:9120 0 0.010
acquired metabolic disease DOID:0060158 0 0.010