Danio rerio

0 known processes

mbd3a

methyl-CpG binding domain protein 3a

(Aliases: wu:fa98f07)

mbd3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alternative mrna splicing via spliceosome GO:0000380 1 0.468
regulation of mrna splicing via spliceosome GO:0048024 3 0.459
regulation of rna biosynthetic process GO:2001141 213 0.371
cellular macromolecule metabolic process GO:0044260 391 0.320
nucleobase containing compound metabolic process GO:0006139 274 0.298
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.245
organic cyclic compound metabolic process GO:1901360 301 0.236
regulation of macromolecule metabolic process GO:0060255 317 0.220
regulation of cellular metabolic process GO:0031323 320 0.218
nitrogen compound metabolic process GO:0006807 319 0.214
regulation of metabolic process GO:0019222 359 0.189
gene expression GO:0010467 252 0.188
regulation of primary metabolic process GO:0080090 311 0.184
nucleic acid templated transcription GO:0097659 181 0.183
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.173
rna biosynthetic process GO:0032774 181 0.165
regulation of rna metabolic process GO:0051252 224 0.160
organic substance biosynthetic process GO:1901576 289 0.160
regulation of gene expression GO:0010468 265 0.155
negative regulation of biological process GO:0048519 304 0.153
regulation of mrna processing GO:0050684 3 0.153
rna metabolic process GO:0016070 219 0.145
organic cyclic compound biosynthetic process GO:1901362 223 0.143
nucleic acid metabolic process GO:0090304 244 0.142
cellular aromatic compound metabolic process GO:0006725 295 0.140
positive regulation of cellular process GO:0048522 201 0.131
cellular nitrogen compound biosynthetic process GO:0044271 218 0.121
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.119
maintenance of location GO:0051235 4 0.111
negative regulation of macromolecule metabolic process GO:0010605 76 0.103
regulation of nucleic acid templated transcription GO:1903506 213 0.103
proteasomal protein catabolic process GO:0010498 2 0.098
regulation of macromolecule biosynthetic process GO:0010556 225 0.098
ubiquitin dependent protein catabolic process GO:0006511 3 0.093
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.092
regulation of binding GO:0051098 3 0.092
lipid storage GO:0019915 1 0.091
regulation of transcription dna templated GO:0006355 213 0.089
modification dependent macromolecule catabolic process GO:0043632 3 0.088
heart development GO:0007507 313 0.087
heterocycle metabolic process GO:0046483 290 0.085
cellular macromolecule biosynthetic process GO:0034645 224 0.083
cell projection organization GO:0030030 284 0.083
cellular nitrogen compound metabolic process GO:0034641 290 0.080
heterocycle biosynthetic process GO:0018130 215 0.075
development of primary female sexual characteristics GO:0046545 4 0.074
positive regulation of protein complex assembly GO:0031334 2 0.072
regionalization GO:0003002 274 0.071
modification dependent protein catabolic process GO:0019941 3 0.070
regulation of nitrogen compound metabolic process GO:0051171 251 0.067
nuclear transport GO:0051169 4 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.061
regulation of cellular biosynthetic process GO:0031326 245 0.061
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.060
determination of left right symmetry GO:0007368 179 0.060
striated muscle tissue development GO:0014706 110 0.058
mrna splicing via spliceosome GO:0000398 10 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.058
head development GO:0060322 303 0.057
regulation of response to stimulus GO:0048583 269 0.055
cellular amino acid metabolic process GO:0006520 7 0.054
muscle tissue development GO:0060537 110 0.054
negative regulation of metabolic process GO:0009892 86 0.053
dna templated transcription initiation GO:0006352 1 0.053
regulation of signal transduction GO:0009966 225 0.053
intracellular signal transduction GO:0035556 85 0.051
regulation of signaling GO:0023051 235 0.049
cellular protein metabolic process GO:0044267 129 0.049
cell projection morphogenesis GO:0048858 244 0.048
signal transduction GO:0007165 455 0.046
heart morphogenesis GO:0003007 156 0.045
kidney development GO:0001822 92 0.044
cognition GO:0050890 1 0.044
peptidyl lysine methylation GO:0018022 3 0.043
cytoskeleton dependent cytokinesis GO:0061640 3 0.041
death GO:0016265 121 0.041
aromatic compound biosynthetic process GO:0019438 217 0.040
anterior posterior pattern specification GO:0009952 152 0.040
positive regulation of cellular component biogenesis GO:0044089 3 0.040
apoptotic process GO:0006915 116 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
neuron differentiation GO:0030182 353 0.039
positive regulation of cell communication GO:0010647 56 0.038
protein metabolic process GO:0019538 183 0.038
regulation of protein catabolic process GO:0042176 1 0.038
response to organic substance GO:0010033 153 0.038
phagocytosis GO:0006909 3 0.038
protein stabilization GO:0050821 2 0.038
single organism metabolic process GO:0044710 217 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
germ line stem cell maintenance GO:0030718 2 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
transcription dna templated GO:0006351 181 0.037
response to chemical GO:0042221 320 0.036
cellular protein catabolic process GO:0044257 4 0.036
transcription from rna polymerase ii promoter GO:0006366 80 0.036
negative regulation of cellular biosynthetic process GO:0031327 55 0.035
positive regulation of transport GO:0051050 2 0.035
neuron development GO:0048666 262 0.034
regulation of reproductive process GO:2000241 4 0.034
biosynthetic process GO:0009058 294 0.034
regulation of mrna metabolic process GO:1903311 6 0.033
urogenital system development GO:0001655 97 0.032
renal system development GO:0072001 94 0.032
macromolecule modification GO:0043412 111 0.032
negative regulation of cellular metabolic process GO:0031324 77 0.031
retina development in camera type eye GO:0060041 146 0.031
oxoacid metabolic process GO:0043436 31 0.031
larval development GO:0002164 2 0.030
positive regulation of biological process GO:0048518 253 0.030
positive regulation of cell cycle GO:0045787 3 0.029
regulation of chromosome segregation GO:0051983 1 0.029
female meiotic division GO:0007143 2 0.029
regulation of molecular function GO:0065009 70 0.029
localization of cell GO:0051674 244 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
cell part morphogenesis GO:0032990 246 0.028
response to corticosteroid GO:0031960 1 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
protein acylation GO:0043543 3 0.027
organic acid metabolic process GO:0006082 31 0.027
response to glucocorticoid GO:0051384 1 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of biological quality GO:0065008 263 0.027
cellular component biogenesis GO:0044085 178 0.027
response to steroid hormone GO:0048545 35 0.027
peptidyl lysine dimethylation GO:0018027 1 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
protein localization to nucleus GO:0034504 3 0.026
negative regulation of nucleic acid templated transcription GO:1903507 45 0.026
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.026
negative regulation of rna metabolic process GO:0051253 48 0.025
somitogenesis GO:0001756 87 0.025
cellular response to stress GO:0033554 62 0.025
muscle organ development GO:0007517 101 0.025
cellular component morphogenesis GO:0032989 336 0.024
negative regulation of gene expression GO:0010629 65 0.024
blood vessel morphogenesis GO:0048514 216 0.024
cell morphogenesis GO:0000902 289 0.024
blood vessel development GO:0001568 246 0.024
regulation of cell communication GO:0010646 232 0.023
peptidyl lysine acetylation GO:0018394 2 0.023
pole plasm assembly GO:0007315 4 0.023
embryonic heart tube development GO:0035050 133 0.023
response to hexose GO:0009746 3 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.023
establishment of rna localization GO:0051236 3 0.023
response to biotic stimulus GO:0009607 97 0.022
regulation of biosynthetic process GO:0009889 250 0.022
rna polyadenylation GO:0043631 2 0.022
response to endogenous stimulus GO:0009719 83 0.022
cellular biosynthetic process GO:0044249 286 0.022
specification of symmetry GO:0009799 204 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
cilium morphogenesis GO:0060271 85 0.022
response to carbohydrate GO:0009743 3 0.022
ameboidal type cell migration GO:0001667 143 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
positive regulation of myeloid cell differentiation GO:0045639 2 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
transport GO:0006810 220 0.021
rna splicing via transesterification reactions GO:0000375 10 0.021
embryonic limb morphogenesis GO:0030326 2 0.021
meiotic cell cycle process GO:1903046 3 0.021
amine metabolic process GO:0009308 2 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
positive regulation of muscle cell differentiation GO:0051149 1 0.020
cellular ketone metabolic process GO:0042180 11 0.020
regulation of circadian rhythm GO:0042752 4 0.020
generation of neurons GO:0048699 385 0.020
small molecule metabolic process GO:0044281 77 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
post embryonic organ development GO:0048569 4 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
regulation of protein ubiquitination GO:0031396 3 0.019
regulation of translational initiation GO:0006446 1 0.019
cellular component movement GO:0006928 335 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
chordate embryonic development GO:0043009 271 0.019
cell motility GO:0048870 244 0.019
positive regulation of chromosome segregation GO:0051984 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
convergent extension GO:0060026 118 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
response to monosaccharide GO:0034284 3 0.019
odontogenesis of dentin containing tooth GO:0042475 1 0.019
single organism organelle organization GO:1902589 199 0.019
neuron projection morphogenesis GO:0048812 161 0.019
regulation of protein complex assembly GO:0043254 3 0.018
locomotion GO:0040011 313 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
forebrain development GO:0030900 96 0.018
female gonad development GO:0008585 4 0.018
cellular protein modification process GO:0006464 100 0.018
endocardial cushion formation GO:0003272 2 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
phosphorus metabolic process GO:0006793 109 0.018
optic placode formation involved in camera type eye formation GO:0046619 3 0.018
neural tube patterning GO:0021532 33 0.018
biological adhesion GO:0022610 40 0.018
protein acetylation GO:0006473 2 0.018
muscle structure development GO:0061061 196 0.018
aorta development GO:0035904 4 0.018
programmed cell death GO:0012501 119 0.017
cell cycle arrest GO:0007050 1 0.017
heart looping GO:0001947 94 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
regulation of programmed cell death GO:0043067 101 0.017
posterior lateral line system development GO:0048915 46 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
stem cell differentiation GO:0048863 117 0.017
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.017
transcription from rna polymerase iii promoter GO:0006383 1 0.017
central nervous system development GO:0007417 387 0.017
positive regulation of metabolic process GO:0009893 108 0.017
rna localization GO:0006403 4 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
determination of bilateral symmetry GO:0009855 204 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
cell proliferation GO:0008283 80 0.016
regulation of hormone secretion GO:0046883 2 0.016
somite development GO:0061053 96 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
response to hormone GO:0009725 48 0.016
sex determination GO:0007530 1 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
telomere organization GO:0032200 1 0.016
positive regulation of chromosome organization GO:2001252 1 0.016
vasculature development GO:0001944 278 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
adult behavior GO:0030534 2 0.016
brain development GO:0007420 293 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
camera type eye morphogenesis GO:0048593 108 0.015
lipid homeostasis GO:0055088 3 0.015
negative regulation of catabolic process GO:0009895 3 0.015
organelle organization GO:0006996 227 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
mrna metabolic process GO:0016071 20 0.015
developmental programmed cell death GO:0010623 4 0.015
recombinational repair GO:0000725 1 0.015
protein modification process GO:0036211 100 0.015
signal transduction by p53 class mediator GO:0072331 13 0.015
stem cell division GO:0017145 1 0.015
regulation of erythrocyte differentiation GO:0045646 2 0.015
regulation of cell differentiation GO:0045595 142 0.015
negative regulation of biosynthetic process GO:0009890 55 0.015
response to stress GO:0006950 263 0.015
single organism transport GO:0044765 206 0.015
sensory organ development GO:0007423 393 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
neuron projection development GO:0031175 180 0.015
regulation of cell death GO:0010941 103 0.015
cellular response to organic substance GO:0071310 105 0.015
protein homooligomerization GO:0051260 3 0.015
response to glucose GO:0009749 3 0.014
rna transport GO:0050658 2 0.014
cytokinesis GO:0000910 3 0.014
single organism reproductive process GO:0044702 40 0.014
cell fate specification GO:0001708 68 0.014
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.014
nucleic acid transport GO:0050657 2 0.014
positive regulation of multi organism process GO:0043902 3 0.014
meiosis i GO:0007127 1 0.014
meiotic nuclear division GO:0007126 4 0.014
cellular component disassembly GO:0022411 1 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.014
cellular response to external stimulus GO:0071496 2 0.013
response to uv GO:0009411 3 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
cell adhesion GO:0007155 40 0.013
regulation of metal ion transport GO:0010959 4 0.013
membrane invagination GO:0010324 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
lateral inhibition GO:0046331 1 0.013
rna splicing GO:0008380 16 0.013
adherens junction assembly GO:0034333 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
immune system development GO:0002520 191 0.013
carbohydrate homeostasis GO:0033500 1 0.013
hormone secretion GO:0046879 2 0.013
pronephros morphogenesis GO:0072114 14 0.013
hormone transport GO:0009914 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
positive regulation of programmed cell death GO:0043068 29 0.013
male meiosis GO:0007140 2 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
axonogenesis GO:0007409 152 0.012
chemical homeostasis GO:0048878 49 0.012
mrna processing GO:0006397 14 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
endocrine hormone secretion GO:0060986 2 0.012
positive regulation of immune effector process GO:0002699 3 0.012
kidney morphogenesis GO:0060993 15 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
regulation of anterior head development GO:2000742 2 0.012
locomotor rhythm GO:0045475 3 0.012
gtp catabolic process GO:0006184 2 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of cytokine production GO:0001817 3 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
regeneration GO:0031099 91 0.012
behavior GO:0007610 74 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
rna export from nucleus GO:0006405 1 0.012
multicellular organism growth GO:0035264 4 0.012
atp catabolic process GO:0006200 4 0.012
endodermal cell fate determination GO:0007493 2 0.012
posterior lateral line neuromast primordium migration GO:0048920 12 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
mesenchyme development GO:0060485 127 0.012
regulation of signal transduction by p53 class mediator GO:1901796 9 0.012
cellular component assembly GO:0022607 170 0.012
regulation of protein phosphorylation GO:0001932 18 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
positive regulation of embryonic development GO:0040019 3 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
nuclear export GO:0051168 1 0.011
response to abiotic stimulus GO:0009628 122 0.011
negative regulation of cell communication GO:0010648 96 0.011
regulation of transferase activity GO:0051338 16 0.011
epithelial cell differentiation GO:0030855 116 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
protein import GO:0017038 3 0.011
cellular response to light stimulus GO:0071482 4 0.011
lipid localization GO:0010876 11 0.011
regulation of developmental process GO:0050793 247 0.011
segmentation GO:0035282 97 0.011
stem cell proliferation GO:0072089 4 0.011
response to growth factor GO:0070848 39 0.011
peptidyl lysine trimethylation GO:0018023 1 0.011
homeostatic process GO:0042592 142 0.011
regulation of protein binding GO:0043393 3 0.011
forebrain cell migration GO:0021885 1 0.011
neuroblast proliferation GO:0007405 2 0.011
cellular response to growth factor stimulus GO:0071363 39 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
palate development GO:0060021 8 0.011
response to lipid GO:0033993 60 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
chromosome organization GO:0051276 31 0.011
regulation of apoptotic process GO:0042981 98 0.010
cell aging GO:0007569 2 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
cell migration GO:0016477 237 0.010
tube closure GO:0060606 1 0.010
cellular response to radiation GO:0071478 4 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010
protein phosphorylation GO:0006468 47 0.010
muscle cell differentiation GO:0042692 139 0.010
histone deacetylation GO:0016575 2 0.010
regulation of axonogenesis GO:0050770 32 0.010
regulation of protein import into nucleus GO:0042306 2 0.010

mbd3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
disease of anatomical entity DOID:7 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
disease of cellular proliferation DOID:14566 0 0.012