Danio rerio

25 known processes

mecom

MDS1 and EVI1 complex locus

(Aliases: im:7140716,evi1,prdm3)

mecom biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound biosynthetic process GO:0034654 205 0.966
Human Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.956
regulation of transcription dna templated GO:0006355 213 0.949
Human Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.943
Human Mouse Fly
chordate embryonic development GO:0043009 271 0.940
transcription dna templated GO:0006351 181 0.935
Human Mouse Fly
diencephalon development GO:0021536 58 0.930
nucleic acid templated transcription GO:0097659 181 0.914
Human Mouse Fly
tube morphogenesis GO:0035239 349 0.914
embryonic organ development GO:0048568 381 0.906
localization of cell GO:0051674 244 0.897
Worm
mesenchyme development GO:0060485 127 0.876
mesenchymal cell development GO:0014031 78 0.849
neural crest cell migration GO:0001755 42 0.844
regulation of macromolecule metabolic process GO:0060255 317 0.827
Human Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.825
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.816
Human Mouse Fly
gene expression GO:0010467 252 0.800
Human Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.797
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.795
Human Mouse Fly
negative regulation of biological process GO:0048519 304 0.792
Human Mouse Worm Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.786
macromolecule biosynthetic process GO:0009059 227 0.779
Human Mouse Fly
neural crest cell development GO:0014032 62 0.765
skeletal system development GO:0001501 181 0.764
kidney development GO:0001822 92 0.763
signal transduction GO:0007165 455 0.763
Human
nephron development GO:0072006 31 0.755
heterocycle biosynthetic process GO:0018130 215 0.754
Human Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.749
stem cell development GO:0048864 82 0.741
hindbrain development GO:0030902 91 0.732
sensory organ development GO:0007423 393 0.732
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.720
Human Mouse Fly
head development GO:0060322 303 0.703
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.695
Human Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.680
pronephric nephron development GO:0039019 14 0.672
negative regulation of biosynthetic process GO:0009890 55 0.670
Human Mouse
axonogenesis GO:0007409 152 0.659
regulation of organ growth GO:0046620 3 0.657
regulation of biological quality GO:0065008 263 0.655
Mouse
otic placode formation GO:0043049 23 0.644
embryonic skeletal system morphogenesis GO:0048704 93 0.638
mesenchymal cell differentiation GO:0048762 87 0.619
positive regulation of rna metabolic process GO:0051254 59 0.607
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.606
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.596
Human Mouse Fly
embryonic skeletal system development GO:0048706 97 0.595
embryonic organ morphogenesis GO:0048562 274 0.589
negative regulation of axon guidance GO:1902668 1 0.589
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.584
negative regulation of rna metabolic process GO:0051253 48 0.557
Human Mouse
epithelial tube formation GO:0072175 19 0.555
branching morphogenesis of an epithelial tube GO:0048754 15 0.550
renal tubule morphogenesis GO:0061333 1 0.530
negative regulation of cellular process GO:0048523 283 0.527
Human Mouse Fly
regionalization GO:0003002 274 0.525
ameboidal type cell migration GO:0001667 143 0.522
cellular macromolecule biosynthetic process GO:0034645 224 0.522
Human Mouse Fly
nephron morphogenesis GO:0072028 2 0.518
regulation of cellular biosynthetic process GO:0031326 245 0.504
Human Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.501
Fly
regulation of rna biosynthetic process GO:2001141 213 0.499
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.488
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.485
Fly
nephron epithelium development GO:0072009 16 0.481
epithelial cell differentiation GO:0030855 116 0.478
regulation of anatomical structure morphogenesis GO:0022603 130 0.475
Fly
stem cell differentiation GO:0048863 117 0.459
Fly
regulation of neurogenesis GO:0050767 87 0.458
Worm Fly
appendage development GO:0048736 80 0.456
Mouse
regulation of developmental process GO:0050793 247 0.443
Worm Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.435
brain development GO:0007420 293 0.430
Mouse
rna metabolic process GO:0016070 219 0.430
Human Mouse Fly
epithelial cell development GO:0002064 42 0.423
gastrulation GO:0007369 208 0.422
otic vesicle morphogenesis GO:0071600 34 0.416
generation of neurons GO:0048699 385 0.416
Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.412
Human Mouse Fly
type b pancreatic cell development GO:0003323 4 0.411
nitrogen compound metabolic process GO:0006807 319 0.411
Human Mouse Fly
camera type eye development GO:0043010 222 0.410
rhombomere development GO:0021546 19 0.406
nephron tubule morphogenesis GO:0072078 1 0.402
neural crest cell differentiation GO:0014033 72 0.397
biosynthetic process GO:0009058 294 0.397
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.396
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.394
Human Mouse Fly
cell growth GO:0016049 57 0.389
regulation of cell differentiation GO:0045595 142 0.388
Worm Fly
endoderm development GO:0007492 49 0.386
astrocyte differentiation GO:0048708 1 0.385
positive regulation of transcription dna templated GO:0045893 57 0.367
Human Mouse
cartilage development GO:0051216 96 0.366
otic vesicle formation GO:0030916 27 0.366
eye development GO:0001654 277 0.360
renal tubule development GO:0061326 5 0.342
growth GO:0040007 174 0.334
neuron projection development GO:0031175 180 0.332
Fly
immune system development GO:0002520 191 0.328
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.328
Fly
branchiomotor neuron axon guidance GO:0021785 1 0.324
regulation of endodermal cell fate specification GO:0042663 15 0.323
digestive system development GO:0055123 289 0.322
negative regulation of cell differentiation GO:0045596 46 0.317
enzyme linked receptor protein signaling pathway GO:0007167 106 0.317
mesoderm development GO:0007498 88 0.312
cell projection organization GO:0030030 284 0.311
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.304
Human Mouse Fly
embryonic limb morphogenesis GO:0030326 2 0.301
Mouse
negative regulation of gene expression GO:0010629 65 0.300
Human Mouse
cellular biosynthetic process GO:0044249 286 0.296
Human Mouse Fly
embryonic pattern specification GO:0009880 44 0.294
rostrocaudal neural tube patterning GO:0021903 29 0.290
gland development GO:0048732 143 0.288
inner ear development GO:0048839 126 0.288
urogenital system development GO:0001655 97 0.287
Mouse
anterior posterior pattern specification GO:0009952 152 0.286
regulation of rna metabolic process GO:0051252 224 0.286
Human Mouse Fly
immune system process GO:0002376 241 0.275
Mouse
cell migration GO:0016477 237 0.275
Worm
kidney vasculature development GO:0061440 2 0.274
forebrain development GO:0030900 96 0.269
Mouse
regulation of anatomical structure size GO:0090066 33 0.267
cellular macromolecule metabolic process GO:0044260 391 0.267
Human Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.260
pronephric nephron tubule development GO:0039020 2 0.256
apoptotic process involved in development GO:1902742 2 0.254
regulation of multicellular organismal development GO:2000026 223 0.249
Worm Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.248
Human Mouse
anatomical structure arrangement GO:0048532 2 0.246
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.244
Human Mouse
glomerulus vasculature development GO:0072012 2 0.244
positive regulation of biosynthetic process GO:0009891 68 0.237
Human Mouse
inner ear receptor cell differentiation GO:0060113 29 0.237
apoptotic process involved in morphogenesis GO:0060561 2 0.230
sensory organ morphogenesis GO:0090596 200 0.229
positive regulation of biological process GO:0048518 253 0.228
Human Mouse
regulation of stem cell differentiation GO:2000736 4 0.228
nucleobase containing compound metabolic process GO:0006139 274 0.228
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.227
Human Mouse Fly
rhombomere morphogenesis GO:0021593 17 0.226
regulation of axon extension involved in axon guidance GO:0048841 6 0.223
patterning of blood vessels GO:0001569 15 0.223
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.221
Human Mouse Fly
inner ear morphogenesis GO:0042472 63 0.220
convergent extension GO:0060026 118 0.219
organic cyclic compound metabolic process GO:1901360 301 0.219
Human Mouse Fly
nephron epithelium morphogenesis GO:0072088 1 0.215
regulation of axon guidance GO:1902667 8 0.213
nephron tubule epithelial cell differentiation GO:0072160 1 0.209
developmental growth involved in morphogenesis GO:0060560 86 0.206
negative regulation of rna biosynthetic process GO:1902679 45 0.206
Human Mouse
developmental growth GO:0048589 166 0.204
regulation of cell communication GO:0010646 232 0.202
Human
pronephros development GO:0048793 69 0.201
dendrite guidance GO:0070983 0 0.201
glomerular epithelial cell fate commitment GO:0072314 4 0.200
morphogenesis of a branching epithelium GO:0061138 16 0.199
regulation of metabolic process GO:0019222 359 0.198
Human Mouse Fly
hepaticobiliary system development GO:0061008 98 0.195
dorsal ventral pattern formation GO:0009953 125 0.191
ectodermal placode morphogenesis GO:0071697 32 0.190
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.189
Human Mouse
angiogenesis GO:0001525 158 0.188
axon extension involved in axon guidance GO:0048846 10 0.183
liver development GO:0001889 96 0.182
negative regulation of chemotaxis GO:0050922 4 0.179
blood vessel development GO:0001568 246 0.178
regulation of biomineral tissue development GO:0070167 2 0.170
kidney epithelium development GO:0072073 23 0.166
otic vesicle development GO:0071599 42 0.166
negative regulation of neurogenesis GO:0050768 20 0.165
kupffer s vesicle development GO:0070121 50 0.162
skeletal system morphogenesis GO:0048705 102 0.161
pectoral fin development GO:0033339 50 0.160
rhombomere 5 development GO:0021571 4 0.160
sympathetic ganglion development GO:0061549 2 0.157
regulation of embryonic development GO:0045995 47 0.157
midbrain hindbrain boundary development GO:0030917 23 0.154
glomerulus development GO:0032835 27 0.153
morphogenesis of a branching structure GO:0001763 21 0.152
kidney morphogenesis GO:0060993 15 0.151
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.149
cell surface receptor signaling pathway GO:0007166 325 0.149
cellular component movement GO:0006928 335 0.148
Worm
epithalamus development GO:0021538 10 0.147
semicircular canal development GO:0060872 24 0.145
locomotion GO:0040011 313 0.143
Worm
negative regulation of nervous system development GO:0051961 22 0.142
sympathetic nervous system development GO:0048485 3 0.142
developmental cell growth GO:0048588 52 0.140
cell differentiation involved in kidney development GO:0061005 13 0.140
adrenal gland development GO:0030325 10 0.139
positive regulation of macromolecule metabolic process GO:0010604 93 0.138
Human Mouse
neuron differentiation GO:0030182 353 0.135
Worm Fly
protein metabolic process GO:0019538 183 0.135
Worm
regulation of cell morphogenesis GO:0022604 42 0.135
Fly
regulation of gastrulation GO:0010470 24 0.134
morphogenesis of embryonic epithelium GO:0016331 30 0.133
taxis GO:0042330 109 0.131
renal system vasculature development GO:0061437 2 0.130
response to fibroblast growth factor GO:0071774 22 0.129
cell fate specification GO:0001708 68 0.128
behavior GO:0007610 74 0.127
Worm
cranial nerve development GO:0021545 42 0.125
central nervous system myelination GO:0022010 2 0.125
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.124
regulation of nucleic acid templated transcription GO:1903506 213 0.123
Human Mouse Fly
regulation of endodermal cell differentiation GO:1903224 15 0.122
tissue remodeling GO:0048771 4 0.121
positive regulation of gene expression GO:0010628 71 0.120
Human Mouse
gabaergic neuron differentiation GO:0097154 2 0.120
axon guidance GO:0007411 86 0.120
neuron development GO:0048666 262 0.119
Fly
cellular protein metabolic process GO:0044267 129 0.118
peripheral nervous system neuron differentiation GO:0048934 28 0.118
peripheral nervous system neuron axonogenesis GO:0048936 13 0.118
response to external stimulus GO:0009605 264 0.115
Mouse
olfactory bulb axon guidance GO:0071678 3 0.113
regulation of neuron projection development GO:0010975 40 0.112
Fly
glomerulus morphogenesis GO:0072102 7 0.112
pronephric glomerulus development GO:0039021 13 0.111
stem cell maintenance GO:0019827 4 0.110
angioblast cell differentiation GO:0035779 2 0.110
positive regulation of cellular biosynthetic process GO:0031328 68 0.107
Human Mouse
vasculature development GO:0001944 278 0.107
establishment of localization GO:0051234 244 0.107
Worm
fourth ventricle development GO:0021592 8 0.106
somatic stem cell maintenance GO:0035019 1 0.106
regulation of cell size GO:0008361 29 0.106
neuron projection extension GO:1990138 45 0.106
rhombomere 6 development GO:0021572 4 0.106
female sex differentiation GO:0046660 4 0.105
somite development GO:0061053 96 0.104
negative regulation of nuclear division GO:0051784 3 0.104
epidermal cell differentiation GO:0009913 36 0.104
eye morphogenesis GO:0048592 144 0.103
convergent extension involved in gastrulation GO:0060027 71 0.103
negative chemotaxis GO:0050919 1 0.101
neuron projection guidance GO:0097485 86 0.100
negative regulation of axon extension GO:0030517 7 0.099
heart development GO:0007507 313 0.098
Mouse
regulation of response to stimulus GO:0048583 269 0.097
Human
neural tube development GO:0021915 62 0.096
negative regulation of cellular biosynthetic process GO:0031327 55 0.096
Human Mouse
central nervous system development GO:0007417 387 0.095
Mouse
epithelial cell fate commitment GO:0072148 11 0.095
myelination of lateral line nerve axons GO:0048897 5 0.094
amine metabolic process GO:0009308 2 0.094
negative regulation of multicellular organismal process GO:0051241 69 0.093
Worm
tissue regeneration GO:0042246 74 0.093
embryonic skeletal joint development GO:0072498 3 0.092
autonomic nervous system development GO:0048483 19 0.092
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.092
Human Mouse
renal system development GO:0072001 94 0.090
Mouse
embryonic neurocranium morphogenesis GO:0048702 15 0.090
cell migration involved in heart development GO:0060973 22 0.090
cell morphogenesis GO:0000902 289 0.089
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.089
Human Mouse
positive regulation of metabolic process GO:0009893 108 0.089
Human Mouse
regulation of neuron differentiation GO:0045664 56 0.087
Worm Fly
cell motility GO:0048870 244 0.087
Worm
closure of optic fissure GO:0061386 6 0.087
mechanoreceptor differentiation GO:0042490 37 0.085
nerve development GO:0021675 45 0.084
ear development GO:0043583 127 0.084
regulation of mrna processing GO:0050684 3 0.083
glial cell development GO:0021782 20 0.082
female gonad development GO:0008585 4 0.082
tube formation GO:0035148 25 0.081
neuron fate determination GO:0048664 2 0.080
negative regulation of transcription dna templated GO:0045892 45 0.080
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.079
Human Mouse
auditory receptor cell fate commitment GO:0009912 4 0.079
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.078
muscle cell fate determination GO:0007521 1 0.078
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.077
histone lysine methylation GO:0034968 12 0.076
gliogenesis GO:0042063 45 0.076
regulation of bone mineralization GO:0030500 2 0.076
segmentation GO:0035282 97 0.074
positive regulation of gastrulation GO:2000543 2 0.074
pancreas development GO:0031016 84 0.073
biomineral tissue development GO:0031214 13 0.073
pancreatic a cell development GO:0003322 2 0.070
histone methylation GO:0016571 13 0.070
positive regulation of developmental process GO:0051094 50 0.070
nephric duct development GO:0072176 13 0.069
connective tissue development GO:0061448 99 0.069
retina development in camera type eye GO:0060041 146 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.068
Mouse
negative regulation of stem cell differentiation GO:2000737 2 0.068
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.067
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.066
cellular protein modification process GO:0006464 100 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.065
regulation of cell fate commitment GO:0010453 22 0.064
hair cell differentiation GO:0035315 32 0.064
response to organic substance GO:0010033 153 0.064
nucleic acid metabolic process GO:0090304 244 0.063
Human Mouse Fly
gastrulation with mouth forming second GO:0001702 44 0.063
negative regulation of cellular metabolic process GO:0031324 77 0.063
Human Mouse
regulation of glial cell differentiation GO:0045685 4 0.063
cell proliferation in hindbrain GO:0021534 4 0.063
hypothalamus development GO:0021854 14 0.062
ectodermal placode development GO:0071696 37 0.062
spinal cord development GO:0021510 46 0.061
muscle structure development GO:0061061 196 0.061
negative regulation of developmental process GO:0051093 65 0.061
Worm
embryonic epithelial tube formation GO:0001838 17 0.060
epidermal cell fate specification GO:0009957 4 0.060
neuron fate commitment GO:0048663 26 0.060
lateral inhibition GO:0046331 1 0.060
regulation of cell development GO:0060284 100 0.058
Worm Fly
mesodermal cell fate specification GO:0007501 12 0.058
programmed cell death GO:0012501 119 0.058
Human
negative regulation of neuron differentiation GO:0045665 10 0.058
hematopoietic or lymphoid organ development GO:0048534 191 0.058
Mouse
hypothalamus cell differentiation GO:0021979 4 0.057
cell death GO:0008219 121 0.056
Human
axon ensheathment in central nervous system GO:0032291 2 0.056
epithelial cell morphogenesis GO:0003382 2 0.056
ear morphogenesis GO:0042471 64 0.056
macromolecule methylation GO:0043414 19 0.054
regulation of heart growth GO:0060420 2 0.054
negative regulation of cell growth GO:0030308 7 0.053
mesoderm morphogenesis GO:0048332 51 0.053
negative regulation of mitosis GO:0045839 3 0.053
wound healing GO:0042060 90 0.052
regulation of axon extension GO:0030516 24 0.052
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.052
Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.052
embryonic digestive tract morphogenesis GO:0048557 3 0.051
regulation of mrna splicing via spliceosome GO:0048024 3 0.051
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.050
Human Mouse
cell part morphogenesis GO:0032990 246 0.050
Fly
cell migration to the midline involved in heart development GO:0003318 12 0.050
glomerular visceral epithelial cell fate commitment GO:0072149 4 0.049
embryonic skeletal joint morphogenesis GO:0060272 3 0.049
glandular epithelial cell differentiation GO:0002067 9 0.049
distal tubule development GO:0072017 1 0.048
nephric duct morphogenesis GO:0072178 7 0.048
cellular component assembly GO:0022607 170 0.048
ventricular system development GO:0021591 12 0.048
facial nerve morphogenesis GO:0021610 1 0.048
embryonic appendage morphogenesis GO:0035113 30 0.048
Mouse
axon development GO:0061564 166 0.047
response to chemical GO:0042221 320 0.047
negative regulation of axonogenesis GO:0050771 7 0.047
sex determination GO:0007530 1 0.047
endodermal cell fate commitment GO:0001711 18 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.047
response to endogenous stimulus GO:0009719 83 0.046
embryonic digestive tract development GO:0048566 4 0.046
digestive tract morphogenesis GO:0048546 231 0.046
forebrain regionalization GO:0021871 4 0.046
positive regulation of nucleic acid templated transcription GO:1903508 57 0.046
Human Mouse
regulation of cell cycle GO:0051726 52 0.045
Human
system process GO:0003008 185 0.045
regulation of locomotion GO:0040012 55 0.044
Worm
embryonic camera type eye formation GO:0060900 10 0.044
limbic system development GO:0021761 16 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.043
Human Mouse
fin development GO:0033333 77 0.043
muscle tissue development GO:0060537 110 0.041
positive regulation of embryonic development GO:0040019 3 0.041
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.040
nephron tubule development GO:0072080 4 0.040
synaptic target recognition GO:0008039 1 0.040
regulation of protein metabolic process GO:0051246 56 0.040
wnt signaling pathway GO:0016055 80 0.040
striated muscle tissue development GO:0014706 110 0.039
epidermis development GO:0008544 48 0.039
response to stress GO:0006950 263 0.039
Human Mouse
rhombomere 5 morphogenesis GO:0021664 1 0.039
pectoral fin morphogenesis GO:0035138 29 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
axis specification GO:0009798 43 0.038
response to oxygen containing compound GO:1901700 55 0.038
habenula development GO:0021986 9 0.037
response to glucocorticoid GO:0051384 1 0.037
larval development GO:0002164 2 0.036
Worm
otolith development GO:0048840 32 0.036
negative regulation of cell development GO:0010721 26 0.036
negative regulation of apoptotic process GO:0043066 55 0.036
fin morphogenesis GO:0033334 53 0.036
cell differentiation in spinal cord GO:0021515 40 0.036
regulation of cellular component organization GO:0051128 86 0.036
Fly
formation of primary germ layer GO:0001704 62 0.035
regulation of protein complex assembly GO:0043254 3 0.035
central nervous system neuron differentiation GO:0021953 74 0.035
hindbrain morphogenesis GO:0021575 22 0.035
multicellular organismal signaling GO:0035637 22 0.035
blood vessel morphogenesis GO:0048514 216 0.035
regulation of bone remodeling GO:0046850 2 0.034
neural plate anterior posterior regionalization GO:0021999 8 0.034
glomerular basement membrane development GO:0032836 5 0.034
branching morphogenesis of a nerve GO:0048755 4 0.034
regulation of endothelial cell differentiation GO:0045601 3 0.034
chemotaxis GO:0006935 104 0.033
cardioblast migration GO:0003260 7 0.033
cell proliferation GO:0008283 80 0.033
Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.033
Fly
negative regulation of reproductive process GO:2000242 3 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.033
Human Mouse
regeneration GO:0031099 91 0.033
semicircular canal morphogenesis GO:0048752 18 0.032
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.032
pronephric glomerulus morphogenesis GO:0035775 6 0.032
telencephalon development GO:0021537 14 0.032
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.032
epithelial cell differentiation involved in kidney development GO:0035850 13 0.031
regulation of cell projection organization GO:0031344 44 0.031
Fly
rhombomere boundary formation GO:0021654 10 0.031
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.031
sprouting angiogenesis GO:0002040 53 0.030
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.030
neural tube patterning GO:0021532 33 0.030
somitogenesis GO:0001756 87 0.030
catechol containing compound biosynthetic process GO:0009713 2 0.030
auditory receptor cell differentiation GO:0042491 15 0.030
catecholamine biosynthetic process GO:0042423 2 0.030
negative regulation of nucleic acid templated transcription GO:1903507 45 0.030
Human Mouse
liver morphogenesis GO:0072576 8 0.029
cardiac muscle tissue development GO:0048738 48 0.029
camera type eye morphogenesis GO:0048593 108 0.029
aging GO:0007568 2 0.029
negative regulation of signaling GO:0023057 96 0.029
Human
endoderm formation GO:0001706 29 0.028
catechol containing compound metabolic process GO:0009712 2 0.028
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.028
regulation of protein glycosylation GO:0060049 3 0.028
vasculogenesis GO:0001570 41 0.028
inner ear receptor cell fate commitment GO:0060120 4 0.028
regulation of blood vessel size GO:0050880 2 0.028
cell migration involved in gastrulation GO:0042074 79 0.027
palate development GO:0060021 8 0.027
single organism localization GO:1902578 225 0.027
endocrine pancreas development GO:0031018 27 0.027
positive regulation of multicellular organismal process GO:0051240 52 0.027
transport GO:0006810 220 0.027
Worm
response to growth factor GO:0070848 39 0.027
regulation of developmental growth GO:0048638 38 0.027
regulation of filopodium assembly GO:0051489 2 0.026
regulation of jak stat cascade GO:0046425 3 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
pancreatic d cell differentiation GO:0003311 2 0.026
cellular response to nutrient levels GO:0031669 2 0.026
mitochondrion organization GO:0007005 4 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
Human Mouse
hemopoiesis GO:0030097 183 0.025
Mouse
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.025
regulation of cell proliferation GO:0042127 37 0.025
Mouse Fly
regulation of tube size GO:0035150 2 0.025
axon extension GO:0048675 45 0.025
cellular response to retinoic acid GO:0071300 1 0.025
cell migration involved in vasculogenesis GO:0035441 1 0.025
appendage morphogenesis GO:0035107 56 0.024
Mouse
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.024
digestive tract development GO:0048565 265 0.024
regulation of growth GO:0040008 42 0.024
peripheral nervous system development GO:0007422 55 0.023
macromolecule modification GO:0043412 111 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.023
peptide metabolic process GO:0006518 1 0.022
cellular amine metabolic process GO:0044106 2 0.022
response to monosaccharide GO:0034284 3 0.022
regulation of sarcomere organization GO:0060297 2 0.022
regulation of chemotaxis GO:0050920 18 0.022
positive regulation of axon guidance GO:1902669 1 0.022
anterior commissure morphogenesis GO:0021960 3 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.021
optic nerve development GO:0021554 15 0.021
muscle organ development GO:0007517 101 0.021
negative regulation of cellular component movement GO:0051271 18 0.021
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.021
regulation of cellular response to growth factor stimulus GO:0090287 35 0.021
regulation of cell growth GO:0001558 29 0.020
developmental pigmentation GO:0048066 48 0.020
regulation of cell migration GO:0030334 40 0.020
Worm
ectodermal placode formation GO:0060788 26 0.020
optomotor response GO:0071632 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020

mecom disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.186
organ system cancer DOID:0050686 0 0.145
cancer DOID:162 0 0.145
urinary system cancer DOID:3996 0 0.114
kidney cancer DOID:263 0 0.035
cell type cancer DOID:0050687 0 0.034
disease of anatomical entity DOID:7 0 0.023
urinary system disease DOID:18 0 0.023