Danio rerio

152 known processes

med12

mediator of RNA polymerase II transcription, subunit 12 homolog

med12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.986
Mouse
immune system development GO:0002520 191 0.980
cellular macromolecule metabolic process GO:0044260 391 0.961
regulation of multicellular organismal development GO:2000026 223 0.917
neural tube development GO:0021915 62 0.910
Mouse
ameboidal type cell migration GO:0001667 143 0.856
gene expression GO:0010467 252 0.848
nuclear transport GO:0051169 4 0.814
hematopoietic or lymphoid organ development GO:0048534 191 0.799
rna biosynthetic process GO:0032774 181 0.798
heart jogging GO:0003146 40 0.748
phosphorylation GO:0016310 69 0.727
immune system process GO:0002376 241 0.724
neural tube patterning GO:0021532 33 0.719
regulation of multicellular organismal process GO:0051239 277 0.715
embryonic organ development GO:0048568 381 0.707
positive regulation of cellular metabolic process GO:0031325 94 0.689
cell surface receptor signaling pathway GO:0007166 325 0.683
Mouse
maturation of ssu rrna GO:0030490 1 0.644
vasculature development GO:0001944 278 0.628
head development GO:0060322 303 0.626
intracellular signal transduction GO:0035556 85 0.595
tube morphogenesis GO:0035239 349 0.594
Mouse
nucleocytoplasmic transport GO:0006913 4 0.594
positive regulation of cellular biosynthetic process GO:0031328 68 0.573
convergent extension involved in gastrulation GO:0060027 71 0.568
protein localization to nucleus GO:0034504 3 0.564
phosphate containing compound metabolic process GO:0006796 108 0.563
negative regulation of cellular process GO:0048523 283 0.541
Mouse
embryonic limb morphogenesis GO:0030326 2 0.539
response to biotic stimulus GO:0009607 97 0.532
larval development GO:0002164 2 0.527
regulation of oligodendrocyte differentiation GO:0048713 1 0.485
regulation of primary metabolic process GO:0080090 311 0.467
regulation of signal transduction GO:0009966 225 0.464
cellular nitrogen compound metabolic process GO:0034641 290 0.462
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.448
protein import GO:0017038 3 0.446
mesenchymal cell development GO:0014031 78 0.437
single organism transport GO:0044765 206 0.424
regulation of nitrogen compound metabolic process GO:0051171 251 0.423
digestive tract morphogenesis GO:0048546 231 0.420
establishment of protein localization to organelle GO:0072594 4 0.416
cellular component movement GO:0006928 335 0.416
hematopoietic stem cell differentiation GO:0060218 20 0.406
hepaticobiliary system development GO:0061008 98 0.402
gastrulation GO:0007369 208 0.398
nitrogen compound metabolic process GO:0006807 319 0.397
meiosis i GO:0007127 1 0.396
regulation of multicellular organism growth GO:0040014 4 0.386
digestive system development GO:0055123 289 0.386
regulation of glial cell differentiation GO:0045685 4 0.385
heart morphogenesis GO:0003007 156 0.384
sensory organ development GO:0007423 393 0.382
multicellular organism growth GO:0035264 4 0.366
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.364
lateral line system development GO:0048925 76 0.364
rna processing GO:0006396 25 0.349
positive regulation of transport GO:0051050 2 0.348
positive regulation of cellular process GO:0048522 201 0.339
nuclear import GO:0051170 3 0.331
negative regulation of cytoplasmic transport GO:1903650 2 0.323
macromolecule biosynthetic process GO:0009059 227 0.318
diencephalon development GO:0021536 58 0.316
cardiac atrium development GO:0003230 4 0.310
organic cyclic compound biosynthetic process GO:1901362 223 0.304
eye development GO:0001654 277 0.304
embryonic heart tube morphogenesis GO:0003143 108 0.301
transport GO:0006810 220 0.300
nucleobase containing compound biosynthetic process GO:0034654 205 0.300
regulation of signaling GO:0023051 235 0.298
protein import into nucleus GO:0006606 3 0.294
myeloid cell homeostasis GO:0002262 56 0.293
rostrocaudal neural tube patterning GO:0021903 29 0.291
regulation of transcription dna templated GO:0006355 213 0.282
organelle organization GO:0006996 227 0.281
eye morphogenesis GO:0048592 144 0.278
heart looping GO:0001947 94 0.277
meiotic spindle organization GO:0000212 1 0.272
neural crest cell differentiation GO:0014033 72 0.271
cellular protein metabolic process GO:0044267 129 0.270
macromolecule modification GO:0043412 111 0.266
single organism metabolic process GO:0044710 217 0.266
regulation of phosphorus metabolic process GO:0051174 43 0.266
somatic muscle development GO:0007525 4 0.264
taxis GO:0042330 109 0.259
aromatic compound biosynthetic process GO:0019438 217 0.259
localization of cell GO:0051674 244 0.259
protein autoubiquitination GO:0051865 3 0.256
single organism nuclear import GO:1902593 3 0.255
negative regulation of protein transport GO:0051224 3 0.250
olfactory bulb development GO:0021772 4 0.248
negative regulation of biological process GO:0048519 304 0.246
Mouse
response to chemical GO:0042221 320 0.245
nucleobase containing compound metabolic process GO:0006139 274 0.244
embryonic hemopoiesis GO:0035162 53 0.242
leukocyte activation GO:0045321 12 0.240
inner ear development GO:0048839 126 0.238
somite development GO:0061053 96 0.236
Mouse
glial cell development GO:0021782 20 0.230
Mouse
neural crest cell development GO:0014032 62 0.229
phosphorus metabolic process GO:0006793 109 0.228
cellular nitrogen compound biosynthetic process GO:0044271 218 0.228
specification of axis polarity GO:0065001 4 0.228
erythrocyte homeostasis GO:0034101 55 0.226
myeloid cell differentiation GO:0030099 86 0.225
aorta development GO:0035904 4 0.223
cellular aromatic compound metabolic process GO:0006725 295 0.223
digestive tract development GO:0048565 265 0.222
kidney development GO:0001822 92 0.218
spindle assembly involved in female meiosis GO:0007056 1 0.217
positive regulation of epithelial cell proliferation GO:0050679 1 0.217
negative regulation of signaling GO:0023057 96 0.216
nucleic acid metabolic process GO:0090304 244 0.215
midbrain hindbrain boundary development GO:0030917 23 0.214
regulation of cellular biosynthetic process GO:0031326 245 0.214
lateral line development GO:0048882 66 0.213
brain development GO:0007420 293 0.213
cellular component morphogenesis GO:0032989 336 0.212
muscle structure development GO:0061061 196 0.207
sensory organ morphogenesis GO:0090596 200 0.205
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.203
morphogenesis of an epithelium GO:0002009 333 0.200
Mouse
determination of left right asymmetry in diencephalon GO:0035462 4 0.199
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.196
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.195
positive regulation of cellular catabolic process GO:0031331 3 0.194
atrial ventricular junction remodeling GO:0003294 2 0.194
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.193
cellular response to organic substance GO:0071310 105 0.192
regulation of developmental process GO:0050793 247 0.192
ribosomal small subunit biogenesis GO:0042274 2 0.192
negative regulation of histone methylation GO:0031061 1 0.189
organic cyclic compound metabolic process GO:1901360 301 0.187
forebrain regionalization GO:0021871 4 0.186
taste bud formation GO:0061195 3 0.185
negative regulation of signal transduction GO:0009968 94 0.182
regulation of gene expression GO:0010468 265 0.182
growth GO:0040007 174 0.180
Mouse
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.179
homeostasis of number of cells GO:0048872 62 0.178
neural crest cell migration GO:0001755 42 0.177
hindbrain development GO:0030902 91 0.177
central nervous system neuron differentiation GO:0021953 74 0.176
camera type eye development GO:0043010 222 0.176
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.176
positive regulation of cell communication GO:0010647 56 0.176
endocardium development GO:0003157 9 0.173
regulation of cell differentiation GO:0045595 142 0.173
renal system development GO:0072001 94 0.173
aorta morphogenesis GO:0035909 3 0.168
regulation of response to stimulus GO:0048583 269 0.168
transcription from rna polymerase ii promoter GO:0006366 80 0.168
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.167
homeostasis of number of cells within a tissue GO:0048873 4 0.167
regulation of metabolic process GO:0019222 359 0.166
cell motility GO:0048870 244 0.164
regulation of macromolecule metabolic process GO:0060255 317 0.162
positive regulation of stem cell proliferation GO:2000648 1 0.162
stem cell differentiation GO:0048863 117 0.160
neuron development GO:0048666 262 0.152
neuron differentiation GO:0030182 353 0.152
mesoderm formation GO:0001707 43 0.151
cell cycle g1 s phase transition GO:0044843 1 0.151
regulation of protein metabolic process GO:0051246 56 0.151
chordate embryonic development GO:0043009 271 0.149
protein targeting to nucleus GO:0044744 3 0.148
system process GO:0003008 185 0.147
blood vessel endothelial cell differentiation GO:0060837 2 0.146
habenula development GO:0021986 9 0.143
blood vessel development GO:0001568 246 0.143
cellular response to stress GO:0033554 62 0.141
regulation of phosphorylation GO:0042325 26 0.140
axon ensheathment GO:0008366 18 0.139
rrna processing GO:0006364 7 0.139
protein modification process GO:0036211 100 0.138
biosynthetic process GO:0009058 294 0.135
embryonic appendage morphogenesis GO:0035113 30 0.131
regulation of nucleocytoplasmic transport GO:0046822 2 0.129
regulation of nervous system development GO:0051960 90 0.129
regulation of intracellular signal transduction GO:1902531 57 0.129
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.128
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.128
regulation of biosynthetic process GO:0009889 250 0.126
establishment of localization in cell GO:0051649 77 0.126
single organism localization GO:1902578 225 0.126
central nervous system formation GO:0021556 1 0.125
cilium organization GO:0044782 71 0.125
spindle assembly involved in meiosis GO:0090306 1 0.123
mesenchyme development GO:0060485 127 0.122
intracellular transport GO:0046907 32 0.121
cell proliferation involved in heart morphogenesis GO:0061323 2 0.119
odontogenesis of dentin containing tooth GO:0042475 1 0.118
cell cycle GO:0007049 93 0.118
protein phosphorylation GO:0006468 47 0.118
regulation of phosphate metabolic process GO:0019220 43 0.118
cellular component biogenesis GO:0044085 178 0.117
rrna metabolic process GO:0016072 8 0.115
cellular response to chemical stimulus GO:0070887 157 0.114
regulation of neurogenesis GO:0050767 87 0.114
g1 s transition of mitotic cell cycle GO:0000082 1 0.114
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.113
embryonic organ morphogenesis GO:0048562 274 0.112
regulation of cellular response to growth factor stimulus GO:0090287 35 0.112
histone deacetylation GO:0016575 2 0.111
neuroblast proliferation GO:0007405 2 0.111
organic substance biosynthetic process GO:1901576 289 0.111
positive regulation of muscle organ development GO:0048636 1 0.110
viral process GO:0016032 1 0.109
multi organism cellular process GO:0044764 2 0.109
cellular localization GO:0051641 97 0.109
endocardium morphogenesis GO:0003160 4 0.109
cellular protein modification process GO:0006464 100 0.108
melanocyte differentiation GO:0030318 26 0.108
positive regulation of signal transduction GO:0009967 56 0.108
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.108
single organism biosynthetic process GO:0044711 71 0.106
ventral spinal cord interneuron specification GO:0021521 3 0.106
central nervous system development GO:0007417 387 0.106
signal transduction by phosphorylation GO:0023014 18 0.105
positive regulation of rna biosynthetic process GO:1902680 57 0.104
regulation of cell communication GO:0010646 232 0.103
positive regulation of catabolic process GO:0009896 4 0.103
axial mesoderm formation GO:0048320 4 0.102
proteasomal protein catabolic process GO:0010498 2 0.101
proepicardium development GO:0003342 4 0.101
hemopoiesis GO:0030097 183 0.101
ncrna processing GO:0034470 8 0.101
neurological system process GO:0050877 62 0.099
blood vessel morphogenesis GO:0048514 216 0.099
regulation of catalytic activity GO:0050790 55 0.099
ensheathment of neurons GO:0007272 18 0.098
regulation of protein ubiquitination GO:0031396 3 0.096
regulation of molecular function GO:0065009 70 0.095
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.095
regulation of heart morphogenesis GO:2000826 17 0.095
spinal cord development GO:0021510 46 0.094
response to other organism GO:0051707 97 0.094
transcription dna templated GO:0006351 181 0.094
organelle assembly GO:0070925 110 0.094
retinal rod cell development GO:0046548 4 0.094
embryonic heart tube development GO:0035050 133 0.093
morphogenesis of follicular epithelium GO:0016333 1 0.093
regulation of cellular metabolic process GO:0031323 320 0.092
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.091
neuron projection development GO:0031175 180 0.091
positive regulation of metabolic process GO:0009893 108 0.090
microtubule polymerization or depolymerization GO:0031109 3 0.090
cell activation GO:0001775 16 0.089
cranial nerve development GO:0021545 42 0.089
negative regulation of cell adhesion GO:0007162 6 0.087
cardiac atrium morphogenesis GO:0003209 2 0.086
regulation of protein catabolic process GO:0042176 1 0.085
sensory system development GO:0048880 76 0.085
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.085
olfactory lobe development GO:0021988 4 0.083
microtubule based process GO:0007017 60 0.083
leukocyte proliferation GO:0070661 1 0.082
generation of neurons GO:0048699 385 0.082
wnt signaling pathway GO:0016055 80 0.082
Mouse
cell proliferation GO:0008283 80 0.082
regulation of macromolecule biosynthetic process GO:0010556 225 0.082
atrioventricular valve formation GO:0003190 3 0.081
taste bud morphogenesis GO:0061194 3 0.080
regulation of production of molecular mediator of immune response GO:0002700 1 0.079
cellular response to endogenous stimulus GO:0071495 68 0.079
autophagy GO:0006914 4 0.079
negative regulation of nervous system development GO:0051961 22 0.079
single organism intracellular transport GO:1902582 25 0.078
positive regulation of ras protein signal transduction GO:0046579 1 0.078
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.078
leukocyte chemotaxis GO:0030595 12 0.078
forebrain development GO:0030900 96 0.078
nerve development GO:0021675 45 0.077
regulation of proteolysis GO:0030162 24 0.076
embryonic digestive tract morphogenesis GO:0048557 3 0.076
enzyme linked receptor protein signaling pathway GO:0007167 106 0.075
auditory receptor cell fate commitment GO:0009912 4 0.075
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 5 0.075
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.075
pigment cell differentiation GO:0050931 38 0.074
establishment of localization GO:0051234 244 0.074
mesodermal cell fate commitment GO:0001710 14 0.074
positive regulation of glial cell differentiation GO:0045687 1 0.074
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.074
arterial endothelial cell differentiation GO:0060842 2 0.074
rhombomere boundary formation GO:0021654 10 0.073
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.073
mesenchymal cell differentiation GO:0048762 87 0.073
determination of dorsal ventral asymmetry GO:0048262 34 0.072
positive regulation of nucleic acid templated transcription GO:1903508 57 0.072
regulation of glucose transport GO:0010827 1 0.071
regulation of immune system process GO:0002682 34 0.070
cell migration involved in heart development GO:0060973 22 0.070
regulation of epithelial cell proliferation GO:0050678 3 0.070
calcium ion transport into cytosol GO:0060402 3 0.069
nuclear export GO:0051168 1 0.069
regulation of cellular protein catabolic process GO:1903362 1 0.069
ribosome biogenesis GO:0042254 9 0.069
negative regulation of protein import into nucleus GO:0042308 2 0.068
cellular biosynthetic process GO:0044249 286 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.068
regulation of meiotic cell cycle GO:0051445 1 0.068
regulation of protein import into nucleus GO:0042306 2 0.068
axon development GO:0061564 166 0.067
response to stress GO:0006950 263 0.067
regulation of cell projection assembly GO:0060491 4 0.067
somitogenesis GO:0001756 87 0.067
Mouse
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.066
endoderm development GO:0007492 49 0.066
gland development GO:0048732 143 0.066
urogenital system development GO:0001655 97 0.066
positive regulation of transcription dna templated GO:0045893 57 0.066
macromolecule localization GO:0033036 54 0.065
pronephros development GO:0048793 69 0.065
mapk cascade GO:0000165 18 0.065
cell differentiation in spinal cord GO:0021515 40 0.065
endodermal cell fate determination GO:0007493 2 0.064
semicircular canal morphogenesis GO:0048752 18 0.064
biological adhesion GO:0022610 40 0.064
single organism cellular localization GO:1902580 46 0.063
regulation of cell proliferation GO:0042127 37 0.063
forebrain neuron differentiation GO:0021879 14 0.063
organelle localization GO:0051640 49 0.063
negative regulation of granulocyte chemotaxis GO:0071623 3 0.063
circulatory system process GO:0003013 87 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.063
regulation of myelination GO:0031641 1 0.062
ear development GO:0043583 127 0.062
negative regulation of mitotic cell cycle GO:0045930 11 0.062
dna templated transcription elongation GO:0006354 3 0.062
cellular protein catabolic process GO:0044257 4 0.062
endodermal digestive tract morphogenesis GO:0061031 2 0.061
regulation of rna biosynthetic process GO:2001141 213 0.061
bmp signaling pathway involved in heart jogging GO:0003303 14 0.061
response to external stimulus GO:0009605 264 0.060
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.060
rna metabolic process GO:0016070 219 0.060
small gtpase mediated signal transduction GO:0007264 8 0.060
swim bladder maturation GO:0048796 5 0.060
cell projection organization GO:0030030 284 0.060
liver development GO:0001889 96 0.059
programmed cell death GO:0012501 119 0.059
formation of primary germ layer GO:0001704 62 0.059
positive regulation of cellular component biogenesis GO:0044089 3 0.058
axonogenesis GO:0007409 152 0.058
divalent inorganic cation homeostasis GO:0072507 22 0.058
membrane hyperpolarization GO:0060081 1 0.058
erythrocyte differentiation GO:0030218 54 0.056
hematopoietic progenitor cell differentiation GO:0002244 23 0.056
pore complex assembly GO:0046931 2 0.056
cilium or flagellum dependent cell motility GO:0001539 4 0.056
response to abiotic stimulus GO:0009628 122 0.056
positive regulation of macromolecule metabolic process GO:0010604 93 0.056
angiogenesis GO:0001525 158 0.056
midbrain development GO:0030901 28 0.056
regulation of protein phosphorylation GO:0001932 18 0.055
negative regulation of cell communication GO:0010648 96 0.055
mitotic g2 dna damage checkpoint GO:0007095 3 0.055
locomotion GO:0040011 313 0.055
regulation of cell activation GO:0050865 1 0.055
muscle cell differentiation GO:0042692 139 0.055
regulation of glial cell proliferation GO:0060251 4 0.055
specification of organ axis polarity GO:0010084 2 0.054
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.053
proximal distal pattern formation GO:0009954 1 0.053
muscle organ development GO:0007517 101 0.053
negative regulation of nuclear division GO:0051784 3 0.053
regulation of systemic arterial blood pressure GO:0003073 1 0.053
negative regulation of protein localization to nucleus GO:1900181 2 0.053
regulation of mapk cascade GO:0043408 14 0.053
otolith morphogenesis GO:0032474 8 0.053
meiotic nuclear division GO:0007126 4 0.053
mitotic cell cycle process GO:1903047 48 0.052
apoptotic process GO:0006915 116 0.052
response to endogenous stimulus GO:0009719 83 0.052
stem cell development GO:0048864 82 0.052
endoderm formation GO:0001706 29 0.052
protein metabolic process GO:0019538 183 0.052
regulation of establishment of protein localization GO:0070201 4 0.052
regulation of protein transport GO:0051223 3 0.052
cell migration GO:0016477 237 0.051
adult behavior GO:0030534 2 0.051
negative regulation of response to stimulus GO:0048585 104 0.051
cellular component assembly GO:0022607 170 0.051
neural plate pattern specification GO:0060896 12 0.050
cell morphogenesis GO:0000902 289 0.050
glial cell proliferation GO:0014009 4 0.050
cardiac endothelial cell differentiation GO:0003348 5 0.050
embryonic eye morphogenesis GO:0048048 30 0.050
heterocycle metabolic process GO:0046483 290 0.050
regulation of protein localization to nucleus GO:1900180 2 0.050
regulation of membrane potential GO:0042391 23 0.049
regulation of eye photoreceptor cell development GO:0042478 2 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.049
regulation of retina development in camera type eye GO:1902866 2 0.049
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.049
death GO:0016265 121 0.049
regulation of stem cell proliferation GO:0072091 2 0.048
positive regulation of rna metabolic process GO:0051254 59 0.048
nitric oxide biosynthetic process GO:0006809 2 0.048
regulation of biological quality GO:0065008 263 0.048
endocardial cell differentiation GO:0060956 5 0.047
stem cell division GO:0017145 1 0.047
regulation of neurological system process GO:0031644 2 0.047
nucleic acid templated transcription GO:0097659 181 0.046
convergent extension GO:0060026 118 0.046
cell adhesion GO:0007155 40 0.046
regulation of skeletal muscle cell differentiation GO:2001014 1 0.046
regulation of protein modification process GO:0031399 29 0.046
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.046
response to external biotic stimulus GO:0043207 97 0.045
floor plate morphogenesis GO:0033505 12 0.045
protein polyubiquitination GO:0000209 4 0.045
spinal cord dorsal ventral patterning GO:0021513 5 0.045
negative regulation of gliogenesis GO:0014014 1 0.045
primitive hemopoiesis GO:0060215 27 0.045
retina layer formation GO:0010842 24 0.044
cytoplasmic transport GO:0016482 11 0.044
negative regulation of intracellular protein transport GO:0090317 3 0.044
astrocyte differentiation GO:0048708 1 0.044
septum transversum development GO:0003343 4 0.044
stem cell fate commitment GO:0048865 1 0.044
regulation of protein targeting GO:1903533 2 0.044
segment polarity determination GO:0007367 1 0.043
cytoskeleton organization GO:0007010 96 0.043
homeostatic process GO:0042592 142 0.043
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.043
nucleic acid transport GO:0050657 2 0.043
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.043
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.043
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.043
cellular response to growth factor stimulus GO:0071363 39 0.042
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.042
forebrain anterior posterior pattern specification GO:0021797 3 0.042
epithelial tube morphogenesis GO:0060562 148 0.042
Mouse
endocardial cushion morphogenesis GO:0003203 3 0.041
connective tissue development GO:0061448 99 0.041
forebrain generation of neurons GO:0021872 14 0.041
cell migration involved in gastrulation GO:0042074 79 0.040
regulation of establishment of planar polarity GO:0090175 4 0.040
Mouse
tissue regeneration GO:0042246 74 0.040
protein localization GO:0008104 40 0.040
paraxial mesoderm morphogenesis GO:0048340 2 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.040
regulation of cell shape GO:0008360 1 0.040
neuronal action potential GO:0019228 18 0.040
floor plate formation GO:0021508 12 0.040
regulation of cell aging GO:0090342 1 0.039
mesenchymal cell proliferation GO:0010463 1 0.039
determination of left right asymmetry in nervous system GO:0035545 4 0.039
endothelial cell fate commitment GO:0060839 3 0.039
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
negative regulation of developmental process GO:0051093 65 0.039
Mouse
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.039
cilium assembly GO:0042384 58 0.039
regulation of programmed cell death GO:0043067 101 0.039
positive regulation of phosphorus metabolic process GO:0010562 21 0.038
pancreas development GO:0031016 84 0.038
neuron projection regeneration GO:0031102 16 0.038
negative regulation of catabolic process GO:0009895 3 0.038
ion homeostasis GO:0050801 41 0.037
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.037
positive regulation of nucleotide catabolic process GO:0030813 1 0.037
positive regulation of biosynthetic process GO:0009891 68 0.037
medial fin morphogenesis GO:0035141 14 0.037
optic placode formation involved in camera type eye formation GO:0046619 3 0.037
i kappab kinase nf kappab signaling GO:0007249 4 0.037
notochord development GO:0030903 54 0.037
unidimensional cell growth GO:0009826 5 0.037
regulation of neuron differentiation GO:0045664 56 0.037
regulation of cell cycle GO:0051726 52 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
positive regulation of chromosome organization GO:2001252 1 0.036
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.036
positive regulation of wound healing GO:0090303 1 0.036
telencephalon development GO:0021537 14 0.036
skin development GO:0043588 54 0.036
regulation of organ growth GO:0046620 3 0.036
commissural neuron axon guidance GO:0071679 3 0.035
regulation of cellular protein metabolic process GO:0032268 52 0.035

med12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
endocrine gland cancer DOID:170 0 0.389
cancer DOID:162 0 0.389
disease of cellular proliferation DOID:14566 0 0.389
organ system cancer DOID:0050686 0 0.389
disease of anatomical entity DOID:7 0 0.122
immune system disease DOID:2914 0 0.109
aplastic anemia DOID:12449 0 0.109
bone marrow disease DOID:4961 0 0.109
anemia DOID:2355 0 0.109
hematopoietic system disease DOID:74 0 0.109
gastrointestinal system cancer DOID:3119 0 0.063
respiratory system cancer DOID:0050615 0 0.047
lung cancer DOID:1324 0 0.047
colon carcinoma DOID:1520 0 0.038
large intestine cancer DOID:5672 0 0.038
colon cancer DOID:219 0 0.038
intestinal cancer DOID:10155 0 0.038
colorectal cancer DOID:9256 0 0.038