Danio rerio

28 known processes

mespb

mesoderm posterior b

(Aliases: mespba,mesp-b)

mespb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cardiac cell fate commitment GO:0060911 1 0.843
Mouse
notch signaling pathway GO:0007219 35 0.817
Mouse
gene expression GO:0010467 252 0.671
Human Mouse
somitogenesis GO:0001756 87 0.669
somite rostral caudal axis specification GO:0032525 5 0.663
Mouse
vasculature development GO:0001944 278 0.614
Human
brain development GO:0007420 293 0.610
positive regulation of gene expression GO:0010628 71 0.593
Human Mouse
cellular biosynthetic process GO:0044249 286 0.584
Human Mouse
signal transduction GO:0007165 455 0.561
Mouse
negative regulation of endodermal cell differentiation GO:1903225 8 0.548
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.487
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.483
Human Mouse
positive regulation of notch signaling pathway GO:0045747 3 0.481
Mouse
rna biosynthetic process GO:0032774 181 0.473
Human Mouse
regulation of gene expression GO:0010468 265 0.469
Human Mouse
regulation of rna metabolic process GO:0051252 224 0.463
Human Mouse
oocyte maturation GO:0001556 4 0.457
head development GO:0060322 303 0.442
formation of primary germ layer GO:0001704 62 0.433
Zebrafish Mouse
localization of cell GO:0051674 244 0.426
Mouse
cardiac chamber formation GO:0003207 4 0.422
Human
organic substance biosynthetic process GO:1901576 289 0.418
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.404
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.403
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.394
Human Mouse
biosynthetic process GO:0009058 294 0.393
Human Mouse
aromatic compound biosynthetic process GO:0019438 217 0.387
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.378
Human Mouse
segmentation GO:0035282 97 0.375
cardiac conduction system development GO:0003161 1 0.372
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.352
heart field specification GO:0003128 1 0.347
Mouse
regulation of multicellular organismal development GO:2000026 223 0.341
Mouse
somite development GO:0061053 96 0.340
heart looping GO:0001947 94 0.316
Mouse
digestive tract development GO:0048565 265 0.316
Zebrafish Mouse
cell migration GO:0016477 237 0.313
Mouse
specification of organ identity GO:0010092 2 0.312
Mouse
transcription dna templated GO:0006351 181 0.301
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.300
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.295
Mouse
regulation of notch signaling pathway GO:0008593 16 0.293
Mouse
nucleic acid metabolic process GO:0090304 244 0.289
Human Mouse
regionalization GO:0003002 274 0.289
cellular component movement GO:0006928 335 0.282
Mouse
regulation of signaling GO:0023051 235 0.282
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.281
Human Mouse
muscle organ development GO:0007517 101 0.277
Fly
organic cyclic compound metabolic process GO:1901360 301 0.273
Human Mouse
anterior posterior pattern specification GO:0009952 152 0.273
cell migration to the midline involved in heart development GO:0003318 12 0.273
Mouse
determination of left right symmetry GO:0007368 179 0.271
Mouse
mesodermal cell migration GO:0008078 12 0.271
Mouse
macromolecule biosynthetic process GO:0009059 227 0.269
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.264
Human Mouse
negative regulation of oocyte development GO:0060283 2 0.259
compound eye development GO:0048749 2 0.257
negative regulation of gastrulation GO:2000542 11 0.257
Mouse
negative regulation of biological process GO:0048519 304 0.247
Mouse
cell fate commitment GO:0045165 99 0.228
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.226
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.225
Human Mouse
specification of symmetry GO:0009799 204 0.225
Mouse
cell motility GO:0048870 244 0.224
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.223
Mouse
digestive tract morphogenesis GO:0048546 231 0.220
Zebrafish Mouse
positive regulation of striated muscle cell differentiation GO:0051155 1 0.202
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.200
Human Mouse
embryonic heart tube development GO:0035050 133 0.200
Mouse
regulation of transcription dna templated GO:0006355 213 0.199
Human Mouse
somite specification GO:0001757 12 0.199
central nervous system development GO:0007417 387 0.197
regulation of cellular biosynthetic process GO:0031326 245 0.196
Human Mouse
negative regulation of cellular process GO:0048523 283 0.195
Mouse
embryonic organ development GO:0048568 381 0.195
Mouse
blood vessel development GO:0001568 246 0.190
Human
regulation of biosynthetic process GO:0009889 250 0.188
Human Mouse
regulation of signal transduction GO:0009966 225 0.186
Mouse
determination of bilateral symmetry GO:0009855 204 0.185
Mouse
response to chemical GO:0042221 320 0.182
muscle attachment GO:0016203 9 0.179
Fly
regulation of organ morphogenesis GO:2000027 35 0.178
Mouse
positive regulation of signaling GO:0023056 56 0.175
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.174
Human Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.174
Mouse
regulation of primary metabolic process GO:0080090 311 0.173
Human Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.173
cellular macromolecule biosynthetic process GO:0034645 224 0.172
Human Mouse
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.171
Mouse
mesodermal cell differentiation GO:0048333 21 0.166
Mouse
negative regulation of endodermal cell fate specification GO:0042664 8 0.165
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.162
Human Mouse
regulation of mesoderm development GO:2000380 11 0.162
Mouse
generation of neurons GO:0048699 385 0.161
mesoderm formation GO:0001707 43 0.159
Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.158
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.157
regulation of embryonic development GO:0045995 47 0.157
Mouse
positive regulation of muscle cell differentiation GO:0051149 1 0.156
Mouse
determination of heart left right asymmetry GO:0061371 117 0.155
Mouse
hemopoiesis GO:0030097 183 0.153
blood vessel morphogenesis GO:0048514 216 0.152
rna metabolic process GO:0016070 219 0.152
Human Mouse
embryonic hemopoiesis GO:0035162 53 0.152
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.152
Human Mouse
eye development GO:0001654 277 0.148
neural retina development GO:0003407 49 0.148
cell surface receptor signaling pathway GO:0007166 325 0.147
Mouse
ameboidal type cell migration GO:0001667 143 0.146
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.146
Human Mouse
angiogenesis GO:0001525 158 0.144
mesodermal cell fate specification GO:0007501 12 0.138
Mouse
nitrogen compound metabolic process GO:0006807 319 0.136
Human Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.128
Mouse
embryonic axis specification GO:0000578 12 0.126
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.125
Human Mouse
neuron projection development GO:0031175 180 0.125
positive regulation of cell fate commitment GO:0010455 1 0.124
Mouse
muscle tissue development GO:0060537 110 0.123
Human
chordate embryonic development GO:0043009 271 0.121
endoderm development GO:0007492 49 0.119
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.117
Mouse
cell fate specification GO:0001708 68 0.114
Mouse
skeletal system development GO:0001501 181 0.114
cell adhesion mediated by integrin GO:0033627 1 0.110
Fly
sensory organ development GO:0007423 393 0.109
tube morphogenesis GO:0035239 349 0.109
Zebrafish Mouse
neuron development GO:0048666 262 0.109
hematopoietic or lymphoid organ development GO:0048534 191 0.103
positive regulation of epithelial cell differentiation GO:0030858 2 0.103
Mouse
striated muscle cell differentiation GO:0051146 129 0.101
Human Mouse
embryonic pattern specification GO:0009880 44 0.100
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.100
Mouse
post anal tail morphogenesis GO:0036342 19 0.099
stem cell division GO:0017145 1 0.099
regulation of metabolic process GO:0019222 359 0.097
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.097
Human Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.096
Mouse
regulation of endodermal cell differentiation GO:1903224 15 0.096
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.095
Human Mouse
photoreceptor cell differentiation GO:0046530 55 0.093
epithelial tube morphogenesis GO:0060562 148 0.093
Mouse
endodermal cell fate specification GO:0001714 17 0.093
Mouse
negative regulation of cell fate commitment GO:0010454 13 0.093
Mouse
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.089
muscle structure development GO:0061061 196 0.088
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 4 0.088
positive regulation of metabolic process GO:0009893 108 0.087
Human Mouse
kupffer s vesicle development GO:0070121 50 0.087
determination of dorsal ventral asymmetry GO:0048262 34 0.087
positive regulation of cell communication GO:0010647 56 0.087
Mouse
sex determination GO:0007530 1 0.087
regulation of endodermal cell fate specification GO:0042663 15 0.086
Mouse
cardiac muscle cell differentiation GO:0055007 30 0.086
Human
endodermal cell differentiation GO:0035987 19 0.086
Mouse
germ cell development GO:0007281 22 0.086
negative regulation of macromolecule metabolic process GO:0010605 76 0.085
Mouse
regulation of response to stimulus GO:0048583 269 0.082
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.082
anterior posterior axis specification GO:0009948 20 0.081
Mouse
digestive system development GO:0055123 289 0.080
Zebrafish Mouse
single organism metabolic process GO:0044710 217 0.078
heart development GO:0007507 313 0.078
Human Mouse
heart morphogenesis GO:0003007 156 0.078
Human Mouse
mesoderm development GO:0007498 88 0.076
Zebrafish Mouse Fly
negative regulation of mesodermal cell fate specification GO:0042662 3 0.075
Mouse
epithelial cell differentiation GO:0030855 116 0.075
Human Mouse
negative regulation of reproductive process GO:2000242 3 0.075
axis specification GO:0009798 43 0.073
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.073
rhombomere development GO:0021546 19 0.073
cardiac atrium development GO:0003230 4 0.073
Human
positive regulation of cellular biosynthetic process GO:0031328 68 0.072
Human Mouse
negative regulation of gene expression GO:0010629 65 0.071
Mouse
immune system process GO:0002376 241 0.071
embryonic organ morphogenesis GO:0048562 274 0.070
Mouse
establishment or maintenance of cell polarity GO:0007163 29 0.070
multicellular organism growth GO:0035264 4 0.070
regulation of reproductive process GO:2000241 4 0.070
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.070
Mouse
larval development GO:0002164 2 0.070
heart jogging GO:0003146 40 0.069
cellular response to biotic stimulus GO:0071216 3 0.069
cellular protein modification process GO:0006464 100 0.068
regulation of cell differentiation GO:0045595 142 0.067
Mouse
bmp signaling pathway involved in heart jogging GO:0003303 14 0.067
cellular amine metabolic process GO:0044106 2 0.066
cellular component biogenesis GO:0044085 178 0.066
convergent extension involved in gastrulation GO:0060027 71 0.066
oxoacid metabolic process GO:0043436 31 0.066
single organism biosynthetic process GO:0044711 71 0.066
regulation of oocyte development GO:0060281 3 0.066
lateral mesoderm development GO:0048368 23 0.065
Mouse
cardioblast migration GO:0003260 7 0.063
Mouse
convergent extension involved in organogenesis GO:0060029 10 0.062
Mouse
maintenance of location GO:0051235 4 0.062
peripheral nervous system development GO:0007422 55 0.062
biological adhesion GO:0022610 40 0.062
Fly
negative regulation of embryonic development GO:0045992 11 0.060
Mouse
immune system development GO:0002520 191 0.060
negative regulation of cellular metabolic process GO:0031324 77 0.060
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.060
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.058
Mouse
cellular protein metabolic process GO:0044267 129 0.057
eye photoreceptor cell differentiation GO:0001754 45 0.057
bmp signaling pathway involved in heart development GO:0061312 15 0.057
positive regulation of macromolecule metabolic process GO:0010604 93 0.057
Human Mouse
sexual reproduction GO:0019953 36 0.056
appendage development GO:0048736 80 0.056
Fly
cellular carbohydrate metabolic process GO:0044262 4 0.056
hepaticobiliary system development GO:0061008 98 0.056
Mouse
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.056
bmp signaling pathway GO:0030509 52 0.055
cartilage morphogenesis GO:0060536 13 0.055
striated muscle tissue development GO:0014706 110 0.055
Human
regulation of gastrulation GO:0010470 24 0.054
Mouse
protein complex biogenesis GO:0070271 30 0.053
negative regulation of cell fate specification GO:0009996 11 0.053
Mouse
regulation of cellular metabolic process GO:0031323 320 0.053
Human Mouse
cell death GO:0008219 121 0.053
astrocyte differentiation GO:0048708 1 0.053
mesoderm morphogenesis GO:0048332 51 0.052
Zebrafish Mouse
protein metabolic process GO:0019538 183 0.052
cellular response to lipopolysaccharide GO:0071222 3 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.052
regulation of developmental process GO:0050793 247 0.052
Mouse
locomotion GO:0040011 313 0.051
Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.051
morphogenesis of an epithelium GO:0002009 333 0.051
Mouse
eye photoreceptor cell development GO:0042462 30 0.050
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.050
Mouse
stem cell development GO:0048864 82 0.050
bone remodeling GO:0046849 2 0.050
cell proliferation GO:0008283 80 0.050
cell migration involved in heart formation GO:0060974 10 0.050
Mouse
homeostatic process GO:0042592 142 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.048
Mouse
regulation of stem cell differentiation GO:2000736 4 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.047
Human Mouse
endodermal cell fate commitment GO:0001711 18 0.047
Mouse
mesodermal cell fate commitment GO:0001710 14 0.046
Mouse
positive regulation of transport GO:0051050 2 0.045
negative regulation of mitosis GO:0045839 3 0.044
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.044
eye morphogenesis GO:0048592 144 0.044
negative regulation of cell communication GO:0010648 96 0.044
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.044
Human Mouse
somatic muscle development GO:0007525 4 0.043
anatomical structure homeostasis GO:0060249 36 0.043
regulation of heart morphogenesis GO:2000826 17 0.043
Mouse
lateral line system development GO:0048925 76 0.042
regulation of cell matrix adhesion GO:0001952 1 0.042
regulation of cytokine production GO:0001817 3 0.041
regulation of dna replication GO:0006275 3 0.041
canonical wnt signaling pathway GO:0060070 48 0.041
Mouse
apoptotic process GO:0006915 116 0.041
positive regulation of response to stimulus GO:0048584 80 0.040
Mouse
positive regulation of cytokine production GO:0001819 2 0.040
cartilage development GO:0051216 96 0.040
negative regulation of rna metabolic process GO:0051253 48 0.040
Mouse
regulation of canonical wnt signaling pathway GO:0060828 34 0.040
Mouse
hepatocyte differentiation GO:0070365 1 0.040
Mouse
macromolecule modification GO:0043412 111 0.039
post embryonic organ development GO:0048569 4 0.039
Fly
positive regulation of multicellular organismal process GO:0051240 52 0.039
Mouse
mesenchyme development GO:0060485 127 0.039
Mouse
organic acid metabolic process GO:0006082 31 0.039
smooth muscle contraction GO:0006939 2 0.038
pectoral fin morphogenesis GO:0035138 29 0.038
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.038
endoderm formation GO:0001706 29 0.038
Mouse
regulation of protein complex assembly GO:0043254 3 0.038
neuron projection morphogenesis GO:0048812 161 0.038
dna templated transcription initiation GO:0006352 1 0.038
negative regulation of cell death GO:0060548 60 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.037
Human Mouse
floor plate morphogenesis GO:0033505 12 0.037
negative regulation of rna biosynthetic process GO:1902679 45 0.036
Mouse
germ line stem cell maintenance GO:0030718 2 0.036
camera type eye development GO:0043010 222 0.036
myeloid cell development GO:0061515 32 0.035
retina development in camera type eye GO:0060041 146 0.035
pancreas development GO:0031016 84 0.035
stem cell proliferation GO:0072089 4 0.035
neuroblast proliferation GO:0007405 2 0.035
negative regulation of biosynthetic process GO:0009890 55 0.035
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.035
lipid storage GO:0019915 1 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.035
cell migration involved in heart development GO:0060973 22 0.034
Mouse
response to retinoic acid GO:0032526 6 0.034
protein modification process GO:0036211 100 0.034
positive regulation of rna biosynthetic process GO:1902680 57 0.034
Human Mouse
regulation of cell fate commitment GO:0010453 22 0.034
Mouse
microtubule based process GO:0007017 60 0.034
amine metabolic process GO:0009308 2 0.034
lateral inhibition GO:0046331 1 0.033
dorsal ventral pattern formation GO:0009953 125 0.033
positive regulation of nucleic acid templated transcription GO:1903508 57 0.033
Human Mouse
regulation of binding GO:0051098 3 0.033
ear development GO:0043583 127 0.033
cellular ketone metabolic process GO:0042180 11 0.033
retina homeostasis GO:0001895 12 0.033
regulation of cellular component movement GO:0051270 55 0.033
organelle localization GO:0051640 49 0.032
cell part morphogenesis GO:0032990 246 0.032
positive regulation of muscle tissue development GO:1901863 1 0.032
developmental induction GO:0031128 10 0.032
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.032
connective tissue development GO:0061448 99 0.032
negative regulation of apoptotic process GO:0043066 55 0.032
response to carbohydrate GO:0009743 3 0.032
positive regulation of transcription dna templated GO:0045893 57 0.031
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.031
Mouse
thyroid gland development GO:0030878 12 0.031
regulation of cell migration GO:0030334 40 0.031
camera type eye photoreceptor cell differentiation GO:0060219 19 0.031
embryonic cranial skeleton morphogenesis GO:0048701 90 0.031
aorta morphogenesis GO:0035909 3 0.031
cell cell signaling GO:0007267 52 0.031
Mouse
protein complex assembly GO:0006461 30 0.030
cell projection morphogenesis GO:0048858 244 0.030
response to organic substance GO:0010033 153 0.030
regulation of cell activation GO:0050865 1 0.030
specification of organ position GO:0010159 3 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.030
intracellular signal transduction GO:0035556 85 0.030
spemann organizer formation at the embryonic shield GO:0060063 2 0.030
cardiac chamber morphogenesis GO:0003206 12 0.029
Human Mouse
positive regulation of secretion GO:0051047 1 0.029
single organism organelle organization GO:1902589 199 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
positive regulation of cellular process GO:0048522 201 0.029
Human Mouse
embryonic digestive tract development GO:0048566 4 0.029
regulation of mesodermal cell fate specification GO:0042661 9 0.029
Mouse
negative regulation of mesoderm development GO:2000381 5 0.029
Mouse
heart valve formation GO:0003188 4 0.028
small molecule metabolic process GO:0044281 77 0.028
negative regulation of smoothened signaling pathway GO:0045879 6 0.028
nerve development GO:0021675 45 0.028
endocrine system development GO:0035270 65 0.028
cell cycle GO:0007049 93 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of cell motility GO:2000145 46 0.028
cell cell signaling involved in cell fate commitment GO:0045168 12 0.027
Mouse
regulation of organ growth GO:0046620 3 0.027
regulation of protein metabolic process GO:0051246 56 0.027
stem cell maintenance GO:0019827 4 0.027
protein phosphorylation GO:0006468 47 0.027
oogenesis GO:0048477 14 0.027
response to lipid GO:0033993 60 0.026
sensory system development GO:0048880 76 0.026
regulation of biological quality GO:0065008 263 0.026
positive regulation of developmental process GO:0051094 50 0.026
Mouse
programmed cell death GO:0012501 119 0.026
fatty acid biosynthetic process GO:0006633 4 0.026
regulation of cell fate specification GO:0042659 20 0.025
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.025
Mouse
gall bladder development GO:0061010 1 0.025
camera type eye morphogenesis GO:0048593 108 0.025
central nervous system neuron differentiation GO:0021953 74 0.025
positive regulation of biological process GO:0048518 253 0.025
Human Mouse
neuron differentiation GO:0030182 353 0.025
dorsal convergence GO:0060030 14 0.025
regulation of wnt signaling pathway GO:0030111 53 0.025
Mouse
cellular response to organic substance GO:0071310 105 0.025
pronephros development GO:0048793 69 0.025
aging GO:0007568 2 0.025
endocrine pancreas development GO:0031018 27 0.024
positive regulation of protein complex assembly GO:0031334 2 0.024
cell projection organization GO:0030030 284 0.024
regulation of cell maturation GO:1903429 1 0.024
gamete generation GO:0007276 33 0.024
floor plate formation GO:0021508 12 0.024
floor plate development GO:0033504 15 0.024
forebrain development GO:0030900 96 0.024
lymphocyte proliferation GO:0046651 1 0.024
positive regulation of cellular protein metabolic process GO:0032270 22 0.024
endodermal cell fate determination GO:0007493 2 0.023
positive regulation of signal transduction GO:0009967 56 0.023
Mouse
wnt signaling pathway GO:0016055 80 0.023
Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.023
cell substrate junction assembly GO:0007044 2 0.023
centrosome organization GO:0051297 1 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
Mouse
positive regulation of dna metabolic process GO:0051054 1 0.023
muscle cell differentiation GO:0042692 139 0.023
Human Mouse
cell morphogenesis GO:0000902 289 0.023
cell differentiation in spinal cord GO:0021515 40 0.023
retina layer formation GO:0010842 24 0.022
ventral spinal cord development GO:0021517 35 0.022
brain morphogenesis GO:0048854 18 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
Human Mouse
skeletal muscle organ development GO:0060538 78 0.022
Fly
positive regulation of rna metabolic process GO:0051254 59 0.022
Human Mouse
pharyngeal muscle development GO:0043282 4 0.022
mitotic cell cycle process GO:1903047 48 0.022
oocyte development GO:0048599 14 0.022
sensory organ morphogenesis GO:0090596 200 0.022
inner ear development GO:0048839 126 0.022
cardiac muscle tissue development GO:0048738 48 0.022
Human
lipid biosynthetic process GO:0008610 22 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
cell proliferation involved in heart morphogenesis GO:0061323 2 0.021
positive regulation of neural precursor cell proliferation GO:2000179 1 0.021
regulation of protein phosphorylation GO:0001932 18 0.021
cellular response to oxygen levels GO:0071453 1 0.021
positive regulation of endothelial cell migration GO:0010595 2 0.021
organ formation GO:0048645 17 0.021
Mouse
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
oligodendrocyte cell fate specification GO:0021778 4 0.021
cardiogenic plate morphogenesis GO:0003142 1 0.021
skeletal system morphogenesis GO:0048705 102 0.020
cardiac chamber development GO:0003205 19 0.020
Human Mouse
negative regulation of nuclear division GO:0051784 3 0.020
negative regulation of cell differentiation GO:0045596 46 0.020
Mouse
skin development GO:0043588 54 0.020
negative regulation of developmental process GO:0051093 65 0.020
Mouse
response to endogenous stimulus GO:0009719 83 0.020
paraxial mesoderm development GO:0048339 8 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
positive regulation of cell activation GO:0050867 1 0.020
regulation of locomotion GO:0040012 55 0.020
tissue remodeling GO:0048771 4 0.020
spinal cord development GO:0021510 46 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
skeletal muscle tissue development GO:0007519 67 0.019
axonogenesis GO:0007409 152 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
regulation of apoptotic process GO:0042981 98 0.019
regulation of cardiac muscle tissue development GO:0055024 1 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
myotube differentiation GO:0014902 45 0.018
positive regulation of muscle organ development GO:0048636 1 0.018
positive regulation of cell differentiation GO:0045597 30 0.018
Mouse
regulation of stem cell proliferation GO:0072091 2 0.018
urogenital system development GO:0001655 97 0.018
regulation of synapse assembly GO:0051963 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
embryonic digestive tract morphogenesis GO:0048557 3 0.018
embryonic appendage morphogenesis GO:0035113 30 0.018
periodic partitioning GO:0007365 1 0.018
death GO:0016265 121 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
vasculogenesis GO:0001570 41 0.017
regulation of localization GO:0032879 104 0.017
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.017
single fertilization GO:0007338 3 0.017
leukocyte proliferation GO:0070661 1 0.017
regulation of vasculature development GO:1901342 33 0.016
phosphorus metabolic process GO:0006793 109 0.016
lateral line development GO:0048882 66 0.016
positive regulation of protein metabolic process GO:0051247 23 0.016
regulation of developmental growth GO:0048638 38 0.016
peripheral nervous system neuron development GO:0048935 22 0.016
foregut morphogenesis GO:0007440 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
arterial endothelial cell differentiation GO:0060842 2 0.016
response to oxygen containing compound GO:1901700 55 0.016
photoreceptor cell fate commitment GO:0046552 1 0.016
abducens nucleus development GO:0021742 2 0.016
endothelial cell fate commitment GO:0060839 3 0.016
pharyngeal system development GO:0060037 18 0.015
septum transversum development GO:0003343 4 0.015
response to stress GO:0006950 263 0.015
aorta development GO:0035904 4 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
determination of dorsal identity GO:0048263 13 0.015
epidermis development GO:0008544 48 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
appendage morphogenesis GO:0035107 56 0.015
Fly
adherens junction organization GO:0034332 4 0.015
glial cell migration GO:0008347 3 0.015
cellular component morphogenesis GO:0032989 336 0.015
pectoral fin development GO:0033339 50 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
regulation of cell development GO:0060284 100 0.015
cell cycle process GO:0022402 53 0.015
cell substrate adhesion GO:0031589 4 0.015
fin development GO:0033333 77 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
swim bladder development GO:0048794 19 0.015
pigmentation GO:0043473 85 0.015
cellular response to growth factor stimulus GO:0071363 39 0.015

mespb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.281
Human
bone disease DOID:0080001 0 0.281
Human
disease of anatomical entity DOID:7 0 0.281
Human
musculoskeletal system disease DOID:17 0 0.281
Human
connective tissue disease DOID:65 0 0.281
Human
dysostosis DOID:1934 0 0.248
Human
nervous system disease DOID:863 0 0.022