Danio rerio

33 known processes

metap2

methionyl aminopeptidase 2

(Aliases: wu:fb98h06,zgc:66250)

metap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myeloid cell differentiation GO:0030099 86 0.441
convergent extension involved in gastrulation GO:0060027 71 0.231
gene expression GO:0010467 252 0.225
immune system process GO:0002376 241 0.183
hematopoietic stem cell differentiation GO:0060218 20 0.182
i kappab kinase nf kappab signaling GO:0007249 4 0.158
muscle organ development GO:0007517 101 0.158
heterocycle biosynthetic process GO:0018130 215 0.156
response to external stimulus GO:0009605 264 0.155
skeletal muscle organ development GO:0060538 78 0.145
cellular macromolecule biosynthetic process GO:0034645 224 0.141
cell cycle GO:0007049 93 0.135
regulation of macromolecule metabolic process GO:0060255 317 0.129
cellular response to external stimulus GO:0071496 2 0.129
morphogenesis of an epithelium GO:0002009 333 0.125
regulation of protein complex assembly GO:0043254 3 0.123
larval development GO:0002164 2 0.118
striated muscle cell differentiation GO:0051146 129 0.118
regulation of gene expression GO:0010468 265 0.116
response to other organism GO:0051707 97 0.110
microtubule based process GO:0007017 60 0.108
muscle structure development GO:0061061 196 0.106
organelle organization GO:0006996 227 0.101
digestive tract development GO:0048565 265 0.101
cellular macromolecule metabolic process GO:0044260 391 0.100
definitive hemopoiesis GO:0060216 18 0.093
hematopoietic or lymphoid organ development GO:0048534 191 0.084
actin filament polymerization GO:0030041 2 0.083
protein polymerization GO:0051258 4 0.082
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.080
neutrophil migration GO:1990266 10 0.079
convergent extension GO:0060026 118 0.079
immune system development GO:0002520 191 0.078
digestive system development GO:0055123 289 0.075
regionalization GO:0003002 274 0.075
regulation of rna metabolic process GO:0051252 224 0.072
homeostasis of number of cells GO:0048872 62 0.070
organic substance biosynthetic process GO:1901576 289 0.070
positive regulation of protein complex assembly GO:0031334 2 0.069
striated muscle tissue development GO:0014706 110 0.069
neuron differentiation GO:0030182 353 0.069
negative regulation of cellular process GO:0048523 283 0.068
nucleic acid metabolic process GO:0090304 244 0.067
muscle cell differentiation GO:0042692 139 0.066
erythrocyte differentiation GO:0030218 54 0.066
hematopoietic progenitor cell differentiation GO:0002244 23 0.066
hemopoiesis GO:0030097 183 0.065
cellular biosynthetic process GO:0044249 286 0.065
regulation of response to stimulus GO:0048583 269 0.064
macrophage differentiation GO:0030225 7 0.064
regulation of primary metabolic process GO:0080090 311 0.063
single organism organelle organization GO:1902589 199 0.062
heterocycle metabolic process GO:0046483 290 0.061
organic cyclic compound metabolic process GO:1901360 301 0.061
death GO:0016265 121 0.060
homeostatic process GO:0042592 142 0.060
positive regulation of cellular component biogenesis GO:0044089 3 0.060
erythrocyte homeostasis GO:0034101 55 0.059
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.059
organic cyclic compound biosynthetic process GO:1901362 223 0.058
cellular response to chemical stimulus GO:0070887 157 0.058
embryonic organ development GO:0048568 381 0.057
biosynthetic process GO:0009058 294 0.056
regulation of biological quality GO:0065008 263 0.055
embryo development ending in birth or egg hatching GO:0009792 271 0.055
Worm
regulation of signal transduction GO:0009966 225 0.054
negative regulation of biological process GO:0048519 304 0.054
regulation of multicellular organismal process GO:0051239 277 0.054
regulation of cellular metabolic process GO:0031323 320 0.054
regulation of protein polymerization GO:0032271 2 0.053
leukocyte migration GO:0050900 15 0.052
cellular nitrogen compound metabolic process GO:0034641 290 0.051
digestive tract morphogenesis GO:0048546 231 0.051
cell surface receptor signaling pathway GO:0007166 325 0.049
aromatic compound biosynthetic process GO:0019438 217 0.049
spermatid differentiation GO:0048515 2 0.049
mitotic cell cycle GO:0000278 64 0.048
myeloid cell homeostasis GO:0002262 56 0.048
cellular response to molecule of bacterial origin GO:0071219 3 0.048
localization of cell GO:0051674 244 0.047
response to biotic stimulus GO:0009607 97 0.047
response to stress GO:0006950 263 0.047
macromolecule biosynthetic process GO:0009059 227 0.046
somite development GO:0061053 96 0.046
vasculature development GO:0001944 278 0.046
signal transduction GO:0007165 455 0.045
epithelial cell morphogenesis GO:0003382 2 0.045
regulation of metabolic process GO:0019222 359 0.044
actin polymerization or depolymerization GO:0008154 2 0.043
spermatid development GO:0007286 2 0.043
negative regulation of multicellular organismal process GO:0051241 69 0.042
angiogenesis GO:0001525 158 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
cellular component movement GO:0006928 335 0.041
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
positive regulation of cellular process GO:0048522 201 0.041
gastrulation GO:0007369 208 0.041
locomotion GO:0040011 313 0.040
system process GO:0003008 185 0.040
establishment of protein localization to organelle GO:0072594 4 0.039
cellular component biogenesis GO:0044085 178 0.038
regulation of rna biosynthetic process GO:2001141 213 0.038
antimicrobial humoral response GO:0019730 2 0.038
nucleic acid templated transcription GO:0097659 181 0.038
regulation of nucleic acid templated transcription GO:1903506 213 0.037
response to chemical GO:0042221 320 0.037
cellular response to lipopolysaccharide GO:0071222 3 0.037
cell cycle process GO:0022402 53 0.036
myotube differentiation GO:0014902 45 0.036
myeloid leukocyte migration GO:0097529 12 0.036
rna metabolic process GO:0016070 219 0.036
cytoskeleton organization GO:0007010 96 0.036
anterior posterior pattern specification GO:0009952 152 0.035
meiotic nuclear division GO:0007126 4 0.035
specification of symmetry GO:0009799 204 0.035
proteasomal protein catabolic process GO:0010498 2 0.034
regulation of synapse assembly GO:0051963 3 0.034
protein complex assembly GO:0006461 30 0.034
nitrogen compound metabolic process GO:0006807 319 0.033
cell motility GO:0048870 244 0.033
actin filament based movement GO:0030048 1 0.033
aging GO:0007568 2 0.033
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.033
macrophage chemotaxis GO:0048246 3 0.032
mitochondrion organization GO:0007005 4 0.032
regulation of transcription dna templated GO:0006355 213 0.031
wnt signaling pathway GO:0016055 80 0.031
positive regulation of biological process GO:0048518 253 0.031
regulation of reproductive process GO:2000241 4 0.031
protein metabolic process GO:0019538 183 0.030
Worm
cellular component assembly GO:0022607 170 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
cellular amide metabolic process GO:0043603 4 0.029
aorta development GO:0035904 4 0.029
pronephros morphogenesis GO:0072114 14 0.029
establishment of localization GO:0051234 244 0.029
Worm
gland development GO:0048732 143 0.029
muscle tissue development GO:0060537 110 0.028
regulation of signaling GO:0023051 235 0.028
positive regulation of protein polymerization GO:0032273 2 0.027
neuron projection development GO:0031175 180 0.027
protein complex biogenesis GO:0070271 30 0.027
embryonic heart tube morphogenesis GO:0003143 108 0.027
determination of heart left right asymmetry GO:0061371 117 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
transcription dna templated GO:0006351 181 0.026
protein localization to nucleus GO:0034504 3 0.026
stem cell differentiation GO:0048863 117 0.026
cellular component morphogenesis GO:0032989 336 0.026
generation of neurons GO:0048699 385 0.026
response to lipid GO:0033993 60 0.026
cellular response to nutrient levels GO:0031669 2 0.026
peptide metabolic process GO:0006518 1 0.025
regulation of cell proliferation GO:0042127 37 0.025
blood circulation GO:0008015 87 0.025
leukocyte differentiation GO:0002521 25 0.025
intracellular signal transduction GO:0035556 85 0.025
regulation of response to biotic stimulus GO:0002831 2 0.025
amine metabolic process GO:0009308 2 0.025
organelle assembly GO:0070925 110 0.025
b cell differentiation GO:0030183 1 0.025
positive regulation of map kinase activity GO:0043406 3 0.024
blood vessel morphogenesis GO:0048514 216 0.024
atrioventricular valve formation GO:0003190 3 0.024
somitogenesis GO:0001756 87 0.024
rna biosynthetic process GO:0032774 181 0.024
heart process GO:0003015 71 0.024
response to abiotic stimulus GO:0009628 122 0.024
protein import GO:0017038 3 0.024
regulation of molecular function GO:0065009 70 0.024
maintenance of location GO:0051235 4 0.023
positive regulation of cytokine production GO:0001819 2 0.023
cellular protein catabolic process GO:0044257 4 0.023
phosphorus metabolic process GO:0006793 109 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
regulation of cell activation GO:0050865 1 0.023
single organism nuclear import GO:1902593 3 0.023
nuclear transport GO:0051169 4 0.023
regulation of organelle assembly GO:1902115 4 0.023
regulation of biosynthetic process GO:0009889 250 0.023
canonical wnt signaling pathway GO:0060070 48 0.023
nuclear import GO:0051170 3 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
regulation of neutrophil migration GO:1902622 6 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
single organism transport GO:0044765 206 0.022
negative regulation of signal transduction GO:0009968 94 0.022
regulation of developmental process GO:0050793 247 0.022
phosphorylation GO:0016310 69 0.022
cellular protein metabolic process GO:0044267 129 0.021
regulation of cytokine production GO:0001817 3 0.021
myeloid cell development GO:0061515 32 0.021
granulocyte migration GO:0097530 11 0.021
programmed cell death GO:0012501 119 0.021
regulation of cell communication GO:0010646 232 0.021
granulocyte chemotaxis GO:0071621 11 0.021
regulation of synapse organization GO:0050807 3 0.020
cellular response to organic substance GO:0071310 105 0.020
positive regulation of multi organism process GO:0043902 3 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
regulation of cellular component organization GO:0051128 86 0.020
regulation of canonical wnt signaling pathway GO:0060828 34 0.020
lipid homeostasis GO:0055088 3 0.020
protein targeting to nucleus GO:0044744 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of metal ion transport GO:0010959 4 0.019
actin mediated cell contraction GO:0070252 1 0.019
leukocyte proliferation GO:0070661 1 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
negative regulation of nervous system development GO:0051961 22 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
stem cell maintenance GO:0019827 4 0.019
leukocyte chemotaxis GO:0030595 12 0.019
cell projection organization GO:0030030 284 0.019
venous blood vessel development GO:0060841 9 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
tube morphogenesis GO:0035239 349 0.019
positive regulation of cell cycle GO:0045787 3 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
b cell activation GO:0042113 2 0.019
axon development GO:0061564 166 0.019
regulation of protein metabolic process GO:0051246 56 0.019
muscle cell development GO:0055001 115 0.018
pericardium development GO:0060039 1 0.018
cell part morphogenesis GO:0032990 246 0.018
regulation of inflammatory response GO:0050727 2 0.018
circulatory system process GO:0003013 87 0.018
endosomal transport GO:0016197 2 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
muscle attachment GO:0016203 9 0.018
multi organism process GO:0051704 134 0.017
Worm
exocrine system development GO:0035272 28 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
protein acetylation GO:0006473 2 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
lymphocyte proliferation GO:0046651 1 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.017
growth GO:0040007 174 0.017
heart looping GO:0001947 94 0.017
regulation of calcium ion transport GO:0051924 2 0.016
monocyte differentiation GO:0030224 2 0.016
response to external biotic stimulus GO:0043207 97 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
protein modification process GO:0036211 100 0.016
neutrophil chemotaxis GO:0030593 10 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
central nervous system development GO:0007417 387 0.016
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
lipid storage GO:0019915 1 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
negative regulation of developmental process GO:0051093 65 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
cellular chemical homeostasis GO:0055082 17 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
epidermis development GO:0008544 48 0.015
brain development GO:0007420 293 0.015
tissue remodeling GO:0048771 4 0.015
female gonad development GO:0008585 4 0.015
sensory organ development GO:0007423 393 0.015
neuroblast proliferation GO:0007405 2 0.015
actin cytoskeleton organization GO:0030036 63 0.015
positive regulation of molecular function GO:0044093 33 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
meiotic chromosome segregation GO:0045132 3 0.015
interspecies interaction between organisms GO:0044419 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of cell shape GO:0008360 1 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
erythrocyte maturation GO:0043249 8 0.014
protein import into nucleus GO:0006606 3 0.014
muscle fiber development GO:0048747 52 0.014
connective tissue development GO:0061448 99 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.014
eye photoreceptor cell development GO:0042462 30 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
somatic stem cell maintenance GO:0035019 1 0.014
determination of left right symmetry GO:0007368 179 0.014
cellular ketone metabolic process GO:0042180 11 0.014
embryonic heart tube development GO:0035050 133 0.014
single organism metabolic process GO:0044710 217 0.014
positive regulation of translation GO:0045727 1 0.014
small molecule metabolic process GO:0044281 77 0.014
striated muscle cell development GO:0055002 108 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
segmentation GO:0035282 97 0.014
heart morphogenesis GO:0003007 156 0.014
protein acylation GO:0043543 3 0.014
sleep GO:0030431 1 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
cell proliferation GO:0008283 80 0.013
protein complex subunit organization GO:0071822 46 0.013
regulation of circadian sleep wake cycle GO:0042749 1 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
establishment of endothelial barrier GO:0061028 3 0.013
head development GO:0060322 303 0.013
regulation of growth GO:0040008 42 0.013
cell death GO:0008219 121 0.013
positive regulation of cytokine biosynthetic process GO:0042108 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
mononuclear cell proliferation GO:0032943 1 0.013
negative regulation of wnt signaling pathway GO:0030178 30 0.013
regulation of response to external stimulus GO:0032101 31 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of cell migration GO:0030334 40 0.013
circadian sleep wake cycle sleep GO:0050802 1 0.013
negative regulation of gene expression GO:0010629 65 0.013
epithelial cell development GO:0002064 42 0.013
limb bud formation GO:0060174 2 0.013
skeletal muscle tissue development GO:0007519 67 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
cell migration GO:0016477 237 0.013
negative regulation of cell communication GO:0010648 96 0.013
retinal rod cell development GO:0046548 4 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
cellular response to starvation GO:0009267 1 0.013
ribosomal small subunit biogenesis GO:0042274 2 0.012
regulation of organ growth GO:0046620 3 0.012
chemical homeostasis GO:0048878 49 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
meiotic cell cycle process GO:1903046 3 0.012
phagocytosis GO:0006909 3 0.012
neuron development GO:0048666 262 0.012
small molecule catabolic process GO:0044282 3 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
positive regulation of metabolic process GO:0009893 108 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
regulation of cell motility GO:2000145 46 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
regulation of cytokine biosynthetic process GO:0042035 1 0.012
eye development GO:0001654 277 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
regulation of neurological system process GO:0031644 2 0.012
gastrulation with mouth forming second GO:0001702 44 0.012
response to oxygen containing compound GO:1901700 55 0.012
embryonic hemopoiesis GO:0035162 53 0.012
transport GO:0006810 220 0.012
Worm
urogenital system development GO:0001655 97 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
circadian sleep wake cycle GO:0042745 2 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
entrainment of circadian clock by photoperiod GO:0043153 1 0.012
metal ion transport GO:0030001 58 0.012
cell proliferation involved in heart morphogenesis GO:0061323 2 0.012
locomotor rhythm GO:0045475 3 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of protein transport GO:0051223 3 0.012
response to organic substance GO:0010033 153 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
cell projection morphogenesis GO:0048858 244 0.011
heart contraction GO:0060047 71 0.011
chordate embryonic development GO:0043009 271 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.011
autophagy GO:0006914 4 0.011
multicellular organism growth GO:0035264 4 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
germ cell development GO:0007281 22 0.011
positive regulation of catabolic process GO:0009896 4 0.011
heart valve formation GO:0003188 4 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
regulation of organelle organization GO:0033043 29 0.011
cellular protein modification process GO:0006464 100 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
cellular amine metabolic process GO:0044106 2 0.011
tissue migration GO:0090130 37 0.011
somatic muscle development GO:0007525 4 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
negative regulation of multi organism process GO:0043901 3 0.011
lymphocyte activation GO:0046649 10 0.011
cell chemotaxis GO:0060326 17 0.011
macromolecule modification GO:0043412 111 0.011
actin filament based process GO:0030029 64 0.011
negative regulation of protein transport GO:0051224 3 0.011
mesenchyme development GO:0060485 127 0.011
regulation of cellular component movement GO:0051270 55 0.011
fat soluble vitamin metabolic process GO:0006775 4 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
cognition GO:0050890 1 0.011
protein complex localization GO:0031503 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
peptidyl amino acid modification GO:0018193 16 0.011
dorsal ventral pattern formation GO:0009953 125 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
spindle assembly involved in mitosis GO:0090307 1 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
organic acid catabolic process GO:0016054 3 0.010
myotube cell development GO:0014904 35 0.010
regulation of programmed cell death GO:0043067 101 0.010
regulation of nervous system development GO:0051960 90 0.010
cell morphogenesis GO:0000902 289 0.010
regulation of blood vessel size GO:0050880 2 0.010
embryonic cranial skeleton morphogenesis GO:0048701 90 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
divalent inorganic cation homeostasis GO:0072507 22 0.010
regulation of binding GO:0051098 3 0.010
cytokine metabolic process GO:0042107 1 0.010
female sex differentiation GO:0046660 4 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
mitotic cell cycle process GO:1903047 48 0.010
spliceosomal complex assembly GO:0000245 1 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
stem cell proliferation GO:0072089 4 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
cytokinesis GO:0000910 3 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
cell matrix adhesion GO:0007160 4 0.010

metap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
disease of anatomical entity DOID:7 0 0.020
organ system cancer DOID:0050686 0 0.019
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.014
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013