Danio rerio

0 known processes

mknk2b

MAP kinase-interacting serine/threonine kinase 2b

(Aliases: mknk2,wu:fb37e05,wz5090)

mknk2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 4 0.182
response to organic substance GO:0010033 153 0.157
lipid storage GO:0019915 1 0.143
regulation of primary metabolic process GO:0080090 311 0.126
regulation of gene expression GO:0010468 265 0.112
larval development GO:0002164 2 0.107
positive regulation of transport GO:0051050 2 0.092
regulation of cellular ketone metabolic process GO:0010565 7 0.091
cellular nitrogen compound metabolic process GO:0034641 290 0.090
cellular response to growth factor stimulus GO:0071363 39 0.085
regulation of biosynthetic process GO:0009889 250 0.084
programmed cell death GO:0012501 119 0.084
Mouse
cellular response to organic substance GO:0071310 105 0.083
cellular biosynthetic process GO:0044249 286 0.083
protein acetylation GO:0006473 2 0.082
maintenance of location GO:0051235 4 0.082
regulation of neural precursor cell proliferation GO:2000177 3 0.080
regulation of binding GO:0051098 3 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.077
internal protein amino acid acetylation GO:0006475 2 0.077
cellular macromolecule metabolic process GO:0044260 391 0.077
Human Mouse Fly
protein acylation GO:0043543 3 0.074
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.074
regulation of macromolecule biosynthetic process GO:0010556 225 0.073
phosphorus metabolic process GO:0006793 109 0.073
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.073
establishment of protein localization to organelle GO:0072594 4 0.072
regulation of response to stimulus GO:0048583 269 0.072
Fly
response to chemical GO:0042221 320 0.071
Human
amine metabolic process GO:0009308 2 0.069
rna metabolic process GO:0016070 219 0.068
peptidyl lysine acetylation GO:0018394 2 0.068
response to abiotic stimulus GO:0009628 122 0.067
aromatic compound biosynthetic process GO:0019438 217 0.066
cellular ketone metabolic process GO:0042180 11 0.066
nucleic acid templated transcription GO:0097659 181 0.065
negative regulation of protein phosphorylation GO:0001933 4 0.063
positive regulation of biological process GO:0048518 253 0.063
regulation of rna metabolic process GO:0051252 224 0.063
regulation of establishment of protein localization GO:0070201 4 0.063
macromolecule biosynthetic process GO:0009059 227 0.063
heart process GO:0003015 71 0.062
regulation of cellular response to growth factor stimulus GO:0090287 35 0.061
cellular amine metabolic process GO:0044106 2 0.058
lateral inhibition GO:0046331 1 0.057
regulation of cell communication GO:0010646 232 0.057
Fly
cellular response to chemical stimulus GO:0070887 157 0.056
Human
determination of bilateral symmetry GO:0009855 204 0.056
extrinsic apoptotic signaling pathway GO:0097191 3 0.055
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.054
endosome organization GO:0007032 2 0.054
regulation of signal transduction GO:0009966 225 0.053
Fly
regulation of rna biosynthetic process GO:2001141 213 0.053
locomotor rhythm GO:0045475 3 0.053
response to external stimulus GO:0009605 264 0.053
regulation of protein localization to nucleus GO:1900180 2 0.053
single organism localization GO:1902578 225 0.052
phagocytosis GO:0006909 3 0.052
gene expression GO:0010467 252 0.052
cellular protein metabolic process GO:0044267 129 0.052
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.051
regulation of cellular metabolic process GO:0031323 320 0.050
organelle organization GO:0006996 227 0.050
energy reserve metabolic process GO:0006112 2 0.050
positive regulation of response to stimulus GO:0048584 80 0.050
regulation of transcription dna templated GO:0006355 213 0.049
specification of symmetry GO:0009799 204 0.049
cellular protein catabolic process GO:0044257 4 0.048
nephron epithelium morphogenesis GO:0072088 1 0.048
cellular carbohydrate metabolic process GO:0044262 4 0.047
regulation of stem cell differentiation GO:2000736 4 0.047
female sex differentiation GO:0046660 4 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.046
negative regulation of protein kinase activity GO:0006469 4 0.046
protein metabolic process GO:0019538 183 0.046
Human Mouse Fly
heart contraction GO:0060047 71 0.046
positive regulation of neuron apoptotic process GO:0043525 1 0.046
positive regulation of metabolic process GO:0009893 108 0.046
lamellipodium assembly GO:0030032 1 0.045
regulation of signaling GO:0023051 235 0.044
Fly
single organism metabolic process GO:0044710 217 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
regulation of blood circulation GO:1903522 32 0.043
regulation of multicellular organism growth GO:0040014 4 0.043
single organism nuclear import GO:1902593 3 0.043
cell cycle g1 s phase transition GO:0044843 1 0.042
nucleocytoplasmic transport GO:0006913 4 0.042
g1 s transition of mitotic cell cycle GO:0000082 1 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
regulation of multicellular organismal process GO:0051239 277 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.040
regulation of protein import into nucleus GO:0042306 2 0.039
positive regulation of apoptotic process GO:0043065 29 0.039
erk1 and erk2 cascade GO:0070371 4 0.039
myeloid cell differentiation GO:0030099 86 0.039
nitrogen compound metabolic process GO:0006807 319 0.039
negative regulation of ras protein signal transduction GO:0046580 1 0.038
Fly
cell death GO:0008219 121 0.038
Mouse
lamellipodium organization GO:0097581 1 0.038
autophagy GO:0006914 4 0.038
positive regulation of protein complex assembly GO:0031334 2 0.038
regulation of protein complex assembly GO:0043254 3 0.038
negative regulation of kinase activity GO:0033673 4 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.037
glucose homeostasis GO:0042593 1 0.037
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
carbohydrate biosynthetic process GO:0016051 1 0.036
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.036
heterocycle metabolic process GO:0046483 290 0.036
response to growth factor GO:0070848 39 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
meiotic nuclear division GO:0007126 4 0.036
heart development GO:0007507 313 0.036
regulation of carbohydrate metabolic process GO:0006109 4 0.036
central nervous system development GO:0007417 387 0.035
positive regulation of stress activated mapk cascade GO:0032874 3 0.035
response to biotic stimulus GO:0009607 97 0.035
regulation of meiotic cell cycle GO:0051445 1 0.035
regulation of autophagy GO:0010506 3 0.035
regulation of metabolic process GO:0019222 359 0.035
protein secretion GO:0009306 1 0.034
regulation of metal ion transport GO:0010959 4 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
response to alkaloid GO:0043279 2 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
regulation of protein targeting GO:1903533 2 0.034
neuron development GO:0048666 262 0.034
response to endogenous stimulus GO:0009719 83 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.034
regulation of protein transport GO:0051223 3 0.034
positive regulation of cell death GO:0010942 29 0.033
positive regulation of cellular biosynthetic process GO:0031328 68 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
transcription from rna polymerase ii promoter GO:0006366 80 0.033
internal peptidyl lysine acetylation GO:0018393 2 0.033
nucleic acid metabolic process GO:0090304 244 0.033
negative regulation of biological process GO:0048519 304 0.033
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
response to uv GO:0009411 3 0.032
nuclear transport GO:0051169 4 0.032
transcription dna templated GO:0006351 181 0.032
pyruvate metabolic process GO:0006090 1 0.032
modification of morphology or physiology of other organism GO:0035821 4 0.032
response to drug GO:0042493 3 0.032
stem cell maintenance GO:0019827 4 0.032
positive regulation of cell activation GO:0050867 1 0.032
protein localization to nucleus GO:0034504 3 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
response to stress GO:0006950 263 0.031
protein targeting to nucleus GO:0044744 3 0.031
cell part morphogenesis GO:0032990 246 0.031
negative regulation of protein complex assembly GO:0031333 1 0.031
regulation of cell shape GO:0008360 1 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
modification dependent protein catabolic process GO:0019941 3 0.031
system process GO:0003008 185 0.031
cellular response to endogenous stimulus GO:0071495 68 0.030
development of primary female sexual characteristics GO:0046545 4 0.030
positive regulation of signaling GO:0023056 56 0.030
regulation of cytokine production GO:0001817 3 0.030
biosynthetic process GO:0009058 294 0.030
embryonic organ morphogenesis GO:0048562 274 0.030
insulin like growth factor receptor signaling pathway GO:0048009 4 0.030
regulation of inflammatory response GO:0050727 2 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
negative regulation of map kinase activity GO:0043407 2 0.029
regulation of developmental process GO:0050793 247 0.029
blood vessel development GO:0001568 246 0.029
signal transduction GO:0007165 455 0.029
Human Mouse Fly
germ line stem cell maintenance GO:0030718 2 0.029
positive regulation of catabolic process GO:0009896 4 0.029
ovulation cycle process GO:0022602 2 0.029
microtubule organizing center organization GO:0031023 1 0.029
organic cyclic compound metabolic process GO:1901360 301 0.028
adult behavior GO:0030534 2 0.028
centrosome organization GO:0051297 1 0.028
multicellular organism growth GO:0035264 4 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
determination of left right symmetry GO:0007368 179 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.028
organic acid metabolic process GO:0006082 31 0.028
sensory organ development GO:0007423 393 0.028
regulation of glucose import GO:0046324 1 0.028
circulatory system process GO:0003013 87 0.028
cellular protein modification process GO:0006464 100 0.028
Human Mouse Fly
cellular amino acid metabolic process GO:0006520 7 0.028
regulation of protein catabolic process GO:0042176 1 0.028
female gonad development GO:0008585 4 0.027
heart morphogenesis GO:0003007 156 0.027
hormone transport GO:0009914 2 0.027
positive regulation of map kinase activity GO:0043406 3 0.027
negative regulation of blood circulation GO:1903523 2 0.027
regulation of erk1 and erk2 cascade GO:0070372 4 0.027
regulation of mitochondrion organization GO:0010821 1 0.027
positive regulation of cell cycle GO:0045787 3 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
cell projection organization GO:0030030 284 0.027
determination of heart left right asymmetry GO:0061371 117 0.027
small molecule metabolic process GO:0044281 77 0.026
regulation of heart contraction GO:0008016 32 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.026
chordate embryonic development GO:0043009 271 0.026
tube morphogenesis GO:0035239 349 0.026
negative regulation of heart contraction GO:0045822 2 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
interaction with host GO:0051701 4 0.026
cognition GO:0050890 1 0.026
regulation of reactive oxygen species metabolic process GO:2000377 2 0.026
establishment of localization GO:0051234 244 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
cell substrate adhesion GO:0031589 4 0.025
oxoacid metabolic process GO:0043436 31 0.025
protein localization to plasma membrane GO:0072659 1 0.025
single organism membrane fusion GO:0044801 2 0.025
regulation of protein polymerization GO:0032271 2 0.025
positive regulation of nucleic acid templated transcription GO:1903508 57 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.025
regulation of stem cell proliferation GO:0072091 2 0.025
nuclear import GO:0051170 3 0.025
odontogenesis of dentin containing tooth GO:0042475 1 0.024
apoptotic process GO:0006915 116 0.024
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.024
negative regulation of signaling GO:0023057 96 0.024
Fly
cellular component movement GO:0006928 335 0.024
regulation of cell differentiation GO:0045595 142 0.024
regulation of dna replication GO:0006275 3 0.024
aging GO:0007568 2 0.024
oocyte maturation GO:0001556 4 0.024
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.024
positive regulation of immune effector process GO:0002699 3 0.024
cell morphogenesis GO:0000902 289 0.023
eye development GO:0001654 277 0.023
protein import into nucleus GO:0006606 3 0.023
phosphorylation GO:0016310 69 0.023
Human Mouse Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.023
response to unfolded protein GO:0006986 2 0.023
regulation of sodium ion transport GO:0002028 2 0.023
regulation of apoptotic process GO:0042981 98 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.022
Human
growth GO:0040007 174 0.022
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
digestive tract morphogenesis GO:0048546 231 0.022
regulation of glucose transport GO:0010827 1 0.022
positive regulation of notch signaling pathway GO:0045747 3 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
protein phosphorylation GO:0006468 47 0.022
Human Mouse Fly
protein polymerization GO:0051258 4 0.022
negative regulation of cellular process GO:0048523 283 0.022
Fly
positive regulation of jnk cascade GO:0046330 3 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
response to topologically incorrect protein GO:0035966 2 0.021
response to oxidative stress GO:0006979 11 0.021
cellular component morphogenesis GO:0032989 336 0.021
ovulation cycle GO:0042698 2 0.021
lymphocyte proliferation GO:0046651 1 0.021
cell matrix adhesion GO:0007160 4 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
signal transduction in absence of ligand GO:0038034 1 0.021
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.021
stem cell proliferation GO:0072089 4 0.021
positive regulation of cell communication GO:0010647 56 0.021
positive regulation of cell adhesion GO:0045785 1 0.021
positive regulation of secretion GO:0051047 1 0.021
organic substance biosynthetic process GO:1901576 289 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.021
response to light stimulus GO:0009416 46 0.021
regulation of cell death GO:0010941 103 0.021
blood vessel morphogenesis GO:0048514 216 0.021
single organism organelle organization GO:1902589 199 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
homeostatic process GO:0042592 142 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.020
brain development GO:0007420 293 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
regulation of epithelial to mesenchymal transition GO:0010717 3 0.020
mononuclear cell proliferation GO:0032943 1 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
protein import GO:0017038 3 0.020
positive regulation of oocyte development GO:0060282 1 0.020
mitochondrial transport GO:0006839 2 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
dna templated transcription elongation GO:0006354 3 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
gtp catabolic process GO:0006184 2 0.020
pathway restricted smad protein phosphorylation GO:0060389 1 0.020
cell proliferation GO:0008283 80 0.020
skin development GO:0043588 54 0.020
positive regulation of transcription dna templated GO:0045893 57 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
Fly
response to other organism GO:0051707 97 0.019
negative regulation of stem cell differentiation GO:2000737 2 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
cell cycle arrest GO:0007050 1 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
Human Mouse Fly
hormone secretion GO:0046879 2 0.019
transport GO:0006810 220 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
regulation of organelle assembly GO:1902115 4 0.019
positive regulation of myeloid cell differentiation GO:0045639 2 0.019
nitric oxide biosynthetic process GO:0006809 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
negative regulation of cytokine production GO:0001818 1 0.019
response to fluid shear stress GO:0034405 2 0.019
endocrine process GO:0050886 2 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
membrane fusion GO:0061025 2 0.019
positive regulation of protein polymerization GO:0032273 2 0.019
regulation of cell activation GO:0050865 1 0.019
regionalization GO:0003002 274 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.018
positive regulation of rna biosynthetic process GO:1902680 57 0.018
regulation of localization GO:0032879 104 0.018
macromolecule modification GO:0043412 111 0.018
Human Mouse Fly
entrainment of circadian clock GO:0009649 2 0.018
organic substance transport GO:0071702 58 0.018
neuroblast proliferation GO:0007405 2 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
regulation of phosphorylation GO:0042325 26 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
embryonic organ development GO:0048568 381 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
Mouse
death GO:0016265 121 0.018
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.018
hemopoiesis GO:0030097 183 0.018
Human
glucose import GO:0046323 2 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
heart looping GO:0001947 94 0.017
stem cell division GO:0017145 1 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
negative regulation of metabolic process GO:0009892 86 0.017
generation of neurons GO:0048699 385 0.017
negative regulation of catabolic process GO:0009895 3 0.017
actin filament polymerization GO:0030041 2 0.017
peptide transport GO:0015833 1 0.017
gtp metabolic process GO:0046039 4 0.017
interspecies interaction between organisms GO:0044419 4 0.017
immune system development GO:0002520 191 0.017
Human
peptidyl serine modification GO:0018209 2 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.017
regulation of hormone secretion GO:0046883 2 0.017
modulation by virus of host morphology or physiology GO:0019048 1 0.017
macromolecule deacylation GO:0098732 3 0.017
regulation of circadian rhythm GO:0042752 4 0.017
cellular component disassembly GO:0022411 1 0.017
olfactory lobe development GO:0021988 4 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
regulation of blood vessel size GO:0050880 2 0.017
centrosome cycle GO:0007098 1 0.017
covalent chromatin modification GO:0016569 20 0.017
leukocyte proliferation GO:0070661 1 0.017
viral process GO:0016032 1 0.017
multi organism cellular process GO:0044764 2 0.016
negative regulation of signal transduction GO:0009968 94 0.016
Fly
positive regulation of cytokine production GO:0001819 2 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
positive regulation of neuron death GO:1901216 1 0.016
membrane invagination GO:0010324 1 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
renal tubule morphogenesis GO:0061333 1 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
Fly
muscle cell migration GO:0014812 4 0.016
regulation of tube size GO:0035150 2 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
nephron morphogenesis GO:0072028 2 0.016
response to oxygen containing compound GO:1901700 55 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
negative regulation of neural precursor cell proliferation GO:2000178 1 0.016
olfactory bulb development GO:0021772 4 0.016
cellular response to topologically incorrect protein GO:0035967 2 0.016
golgi vesicle transport GO:0048193 3 0.016
response to glucose GO:0009749 3 0.016
protein modification process GO:0036211 100 0.016
Human Mouse Fly
regulation of response to cytokine stimulus GO:0060759 3 0.016
carbohydrate homeostasis GO:0033500 1 0.016
protein heterooligomerization GO:0051291 1 0.016
cell projection morphogenesis GO:0048858 244 0.015
negative regulation of cell communication GO:0010648 96 0.015
Fly
positive regulation of signal transduction GO:0009967 56 0.015
negative regulation of catalytic activity GO:0043086 21 0.015
regulation of circadian sleep wake cycle GO:0042749 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
head development GO:0060322 303 0.015
regulation of catalytic activity GO:0050790 55 0.015
protein complex disassembly GO:0043241 1 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
cellular response to radiation GO:0071478 4 0.015
multi organism process GO:0051704 134 0.015
muscle structure development GO:0061061 196 0.015
regulation of reproductive process GO:2000241 4 0.015
exocytosis GO:0006887 1 0.015
protein polyubiquitination GO:0000209 4 0.015
response to inorganic substance GO:0010035 38 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to starvation GO:0009267 1 0.015
regulation of biological quality GO:0065008 263 0.015
phagocytosis engulfment GO:0006911 1 0.015
convergent extension involved in gastrulation GO:0060027 71 0.015
positive regulation of protein metabolic process GO:0051247 23 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
leukocyte differentiation GO:0002521 25 0.015
positive regulation of leukocyte mediated immunity GO:0002705 1 0.015
cell motility GO:0048870 244 0.015
protein complex localization GO:0031503 1 0.015
sphingolipid biosynthetic process GO:0030148 2 0.015
defense response to fungus GO:0050832 2 0.015
nephron tubule morphogenesis GO:0072078 1 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of jak stat cascade GO:0046425 3 0.015
activation of mapk activity GO:0000187 3 0.015
regulation of filopodium assembly GO:0051489 2 0.015
zymogen activation GO:0031638 3 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
Fly
vasculature development GO:0001944 278 0.014
cytokinesis GO:0000910 3 0.014
peptidyl threonine modification GO:0018210 1 0.014
pigmentation GO:0043473 85 0.014
digestive system development GO:0055123 289 0.014
negative regulation of protein import into nucleus GO:0042308 2 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
cellular transition metal ion homeostasis GO:0046916 3 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
response to external biotic stimulus GO:0043207 97 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
response to vitamin GO:0033273 3 0.014
epithelial cell differentiation GO:0030855 116 0.014
centrosome duplication GO:0051298 1 0.014
regulation of molecular function GO:0065009 70 0.014
smad protein complex assembly GO:0007183 1 0.014
epidermis development GO:0008544 48 0.014
response to radiation GO:0009314 51 0.014
convergent extension GO:0060026 118 0.014
neurological system process GO:0050877 62 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
septum transversum development GO:0003343 4 0.014
neuron death GO:0070997 21 0.014
adherens junction organization GO:0034332 4 0.014
sex determination GO:0007530 1 0.014
positive regulation of molecular function GO:0044093 33 0.014
lipid homeostasis GO:0055088 3 0.014
proepicardium development GO:0003342 4 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
regulation of erythrocyte differentiation GO:0045646 2 0.014
ear development GO:0043583 127 0.014
medulla oblongata development GO:0021550 4 0.014
regulation of protein deacetylation GO:0090311 2 0.013
somatic muscle development GO:0007525 4 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
membrane lipid biosynthetic process GO:0046467 2 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
regulation of dna templated transcription in response to stress GO:0043620 0 0.013
spindle assembly GO:0051225 2 0.013
protein depolymerization GO:0051261 1 0.013
meiosis i GO:0007127 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
cell migration GO:0016477 237 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
histone deacetylation GO:0016575 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013

mknk2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.020
organ system cancer DOID:0050686 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017
cardiomyopathy DOID:0050700 0 0.016
muscular disease DOID:0080000 0 0.016
heart disease DOID:114 0 0.016
cardiovascular system disease DOID:1287 0 0.016
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.016
disease of metabolism DOID:0014667 0 0.014