Danio rerio

35 known processes

mll

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

(Aliases: im:7148357)

mll biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound biosynthetic process GO:0019438 217 0.999
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.995
Human Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.991
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.989
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.987
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.982
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.974
Human Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.972
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.969
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.968
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.968
Human Mouse Fly
sensory organ development GO:0007423 393 0.963
regulation of transcription dna templated GO:0006355 213 0.961
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.955
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.955
Human Mouse Fly
rna biosynthetic process GO:0032774 181 0.952
Human Mouse Fly
regulation of metabolic process GO:0019222 359 0.946
Human Mouse Fly
transcription dna templated GO:0006351 181 0.944
Human Mouse Fly
negative regulation of gene expression GO:0010629 65 0.944
organic cyclic compound biosynthetic process GO:1901362 223 0.941
Human Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.939
Human Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.938
Human Mouse Fly
regionalization GO:0003002 274 0.935
Mouse
regulation of biosynthetic process GO:0009889 250 0.935
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.925
Human Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.909
Human Mouse Fly
negative regulation of biological process GO:0048519 304 0.904
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.895
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.864
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.864
Human Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.861
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.859
Human Mouse Fly
biosynthetic process GO:0009058 294 0.853
Human Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.828
Human Mouse Fly
forebrain development GO:0030900 96 0.828
cellular nitrogen compound biosynthetic process GO:0044271 218 0.825
Human Mouse Fly
regulation of signaling GO:0023051 235 0.808
inner ear development GO:0048839 126 0.795
regulation of primary metabolic process GO:0080090 311 0.791
Human Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.781
immune system process GO:0002376 241 0.780
bmp signaling pathway GO:0030509 52 0.773
cellular biosynthetic process GO:0044249 286 0.769
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.764
Human Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.763
Human Mouse Fly
head development GO:0060322 303 0.755
ear development GO:0043583 127 0.754
regulation of nucleic acid templated transcription GO:1903506 213 0.738
Human Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.721
embryonic organ development GO:0048568 381 0.680
Mouse
response to chemical GO:0042221 320 0.678
Human Fly
diencephalon development GO:0021536 58 0.667
cell surface receptor signaling pathway GO:0007166 325 0.648
blood vessel morphogenesis GO:0048514 216 0.643
hemopoiesis GO:0030097 183 0.643
negative regulation of cellular process GO:0048523 283 0.633
Mouse
mesenchyme development GO:0060485 127 0.601
central nervous system development GO:0007417 387 0.598
gene expression GO:0010467 252 0.596
Human Mouse Fly
response to external stimulus GO:0009605 264 0.592
Fly
neuron development GO:0048666 262 0.590
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.583
Human Mouse Fly
immune system development GO:0002520 191 0.580
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.570
mesoderm development GO:0007498 88 0.569
connective tissue development GO:0061448 99 0.566
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.563
brain development GO:0007420 293 0.561
regulation of response to stimulus GO:0048583 269 0.554
Human Fly
gastrulation GO:0007369 208 0.552
negative regulation of rna metabolic process GO:0051253 48 0.551
negative regulation of rna biosynthetic process GO:1902679 45 0.536
cell projection organization GO:0030030 284 0.532
Fly
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.517
negative regulation of cellular biosynthetic process GO:0031327 55 0.495
rna metabolic process GO:0016070 219 0.490
Human Mouse Fly
signal transduction GO:0007165 455 0.470
single organism metabolic process GO:0044710 217 0.461
Human Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.455
Human Mouse Fly
system process GO:0003008 185 0.451
transcription from rna polymerase ii promoter GO:0006366 80 0.435
Human Mouse Fly
response to stress GO:0006950 263 0.423
Fly
neuron differentiation GO:0030182 353 0.422
Fly
positive regulation of rna metabolic process GO:0051254 59 0.421
Human Mouse Fly
anterior posterior pattern specification GO:0009952 152 0.419
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.402
positive regulation of nucleic acid templated transcription GO:1903508 57 0.396
Human Mouse Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.395
blood vessel development GO:0001568 246 0.391
negative regulation of nucleic acid templated transcription GO:1903507 45 0.385
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.379
cellular response to external stimulus GO:0071496 2 0.379
regulation of multicellular organismal process GO:0051239 277 0.362
response to organic substance GO:0010033 153 0.359
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.356
stem cell maintenance GO:0019827 4 0.353
negative regulation of cellular metabolic process GO:0031324 77 0.348
determination of left right symmetry GO:0007368 179 0.343
single organism reproductive process GO:0044702 40 0.333
Fly
skeletal system development GO:0001501 181 0.330
protein metabolic process GO:0019538 183 0.329
Human Mouse Fly
cell motility GO:0048870 244 0.327
Fly
regulation of multicellular organism growth GO:0040014 4 0.326
sensory organ morphogenesis GO:0090596 200 0.320
positive regulation of biological process GO:0048518 253 0.317
Human Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.310
vasculature development GO:0001944 278 0.305
tissue regeneration GO:0042246 74 0.301
chromatin organization GO:0006325 22 0.298
Human Mouse Fly
erythrocyte homeostasis GO:0034101 55 0.288
oligodendrocyte differentiation GO:0048709 23 0.287
positive regulation of cellular process GO:0048522 201 0.286
Human Mouse Fly
regulation of cell communication GO:0010646 232 0.286
angiogenesis GO:0001525 158 0.283
determination of heart left right asymmetry GO:0061371 117 0.280
homeostatic process GO:0042592 142 0.278
developmental growth GO:0048589 166 0.272
aging GO:0007568 2 0.268
embryonic organ morphogenesis GO:0048562 274 0.268
myeloid cell differentiation GO:0030099 86 0.266
central nervous system neuron differentiation GO:0021953 74 0.260
erythrocyte differentiation GO:0030218 54 0.254
cellular component movement GO:0006928 335 0.252
Fly
regulation of signal transduction GO:0009966 225 0.251
cellular response to chemical stimulus GO:0070887 157 0.242
Human
locomotion GO:0040011 313 0.241
Fly
localization of cell GO:0051674 244 0.240
Fly
mediolateral intercalation GO:0060031 3 0.235
tube morphogenesis GO:0035239 349 0.232
programmed cell death GO:0012501 119 0.231
regulation of developmental process GO:0050793 247 0.227
negative regulation of metabolic process GO:0009892 86 0.227
reproduction GO:0000003 40 0.227
Fly
skeletal system morphogenesis GO:0048705 102 0.220
positive regulation of macromolecule metabolic process GO:0010604 93 0.219
Human Mouse Fly
eye development GO:0001654 277 0.216
cell proliferation GO:0008283 80 0.212
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.211
embryonic cranial skeleton morphogenesis GO:0048701 90 0.192
regulation of canonical wnt signaling pathway GO:0060828 34 0.191
mesoderm morphogenesis GO:0048332 51 0.191
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.191
determination of bilateral symmetry GO:0009855 204 0.188
inner ear receptor cell differentiation GO:0060113 29 0.188
ovulation cycle GO:0042698 2 0.186
neurological system process GO:0050877 62 0.183
negative regulation of response to stimulus GO:0048585 104 0.181
camera type eye development GO:0043010 222 0.176
neuron projection morphogenesis GO:0048812 161 0.171
Fly
positive regulation of muscle organ development GO:0048636 1 0.169
retina development in camera type eye GO:0060041 146 0.167
positive regulation of cellular biosynthetic process GO:0031328 68 0.165
Human Mouse Fly
wnt signaling pathway GO:0016055 80 0.159
rhythmic process GO:0048511 21 0.156
protein modification process GO:0036211 100 0.155
Human Mouse Fly
homeostasis of number of cells GO:0048872 62 0.155
mesoderm formation GO:0001707 43 0.153
hindbrain development GO:0030902 91 0.152
positive regulation of rna biosynthetic process GO:1902680 57 0.152
Human Mouse Fly
macromolecule modification GO:0043412 111 0.149
Human Mouse Fly
positive regulation of signaling GO:0023056 56 0.147
artery development GO:0060840 22 0.146
generation of neurons GO:0048699 385 0.141
Fly
negative regulation of biosynthetic process GO:0009890 55 0.140
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.139
Human Mouse Fly
optic placode formation involved in camera type eye formation GO:0046619 3 0.139
oocyte maturation GO:0001556 4 0.138
negative regulation of signal transduction GO:0009968 94 0.138
positive regulation of cell communication GO:0010647 56 0.138
maintenance of location GO:0051235 4 0.137
gliogenesis GO:0042063 45 0.135
positive regulation of metabolic process GO:0009893 108 0.134
Human Mouse Fly
axonogenesis GO:0007409 152 0.133
Fly
heart development GO:0007507 313 0.132
regulation of biological quality GO:0065008 263 0.132
response to endogenous stimulus GO:0009719 83 0.131
striated muscle tissue development GO:0014706 110 0.130
specification of symmetry GO:0009799 204 0.128
organ formation GO:0048645 17 0.127
cellular protein modification process GO:0006464 100 0.125
Human Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.125
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.124
Human Mouse Fly
gland development GO:0048732 143 0.124
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.123
embryonic eye morphogenesis GO:0048048 30 0.122
regulation of cell differentiation GO:0045595 142 0.122
mesenchymal cell differentiation GO:0048762 87 0.121
cellular response to organic substance GO:0071310 105 0.120
axon guidance GO:0007411 86 0.119
Fly
behavior GO:0007610 74 0.119
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.118
regulation of embryonic development GO:0045995 47 0.117
regulation of protein metabolic process GO:0051246 56 0.114
Mouse
growth GO:0040007 174 0.114
cognition GO:0050890 1 0.114
regulation of epithelial cell proliferation GO:0050678 3 0.113
multi organism process GO:0051704 134 0.113
Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.112
pancreas development GO:0031016 84 0.111
neuron projection development GO:0031175 180 0.111
Fly
positive regulation of biosynthetic process GO:0009891 68 0.111
Human Mouse Fly
ear morphogenesis GO:0042471 64 0.109
positive regulation of cell cycle GO:0045787 3 0.108
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.108
response to wounding GO:0009611 116 0.107
developmental maturation GO:0021700 34 0.105
negative regulation of smoothened signaling pathway GO:0045879 6 0.104
female gonad development GO:0008585 4 0.103
embryonic digestive tract morphogenesis GO:0048557 3 0.102
regulation of cell development GO:0060284 100 0.101
small molecule metabolic process GO:0044281 77 0.101
epithalamus development GO:0021538 10 0.101
multicellular organism growth GO:0035264 4 0.100
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.099
ovulation cycle process GO:0022602 2 0.099
morphogenesis of an epithelium GO:0002009 333 0.098
specification of organ position GO:0010159 3 0.097
cellular response to endogenous stimulus GO:0071495 68 0.097
cartilage development GO:0051216 96 0.095
positive regulation of gene expression GO:0010628 71 0.094
Human Mouse Fly
spinal cord anterior posterior patterning GO:0021512 1 0.093
metencephalon development GO:0022037 27 0.092
single fertilization GO:0007338 3 0.091
segment polarity determination GO:0007367 1 0.091
camera type eye morphogenesis GO:0048593 108 0.090
epithelial tube morphogenesis GO:0060562 148 0.089
cellular response to nutrient levels GO:0031669 2 0.089
chordate embryonic development GO:0043009 271 0.089
apoptotic signaling pathway GO:0097190 23 0.088
cell morphogenesis involved in differentiation GO:0000904 195 0.087
Fly
eye morphogenesis GO:0048592 144 0.087
response to radiation GO:0009314 51 0.086
development of primary female sexual characteristics GO:0046545 4 0.086
regulation of growth GO:0040008 42 0.085
heart valve formation GO:0003188 4 0.085
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.084
Fly
glucose homeostasis GO:0042593 1 0.083
embryonic skeletal system development GO:0048706 97 0.082
t cell activation GO:0042110 6 0.081
circadian sleep wake cycle process GO:0022410 2 0.080
cell morphogenesis GO:0000902 289 0.079
Fly
canonical wnt signaling pathway GO:0060070 48 0.078
regulation of cell death GO:0010941 103 0.078
embryonic hemopoiesis GO:0035162 53 0.074
Mouse
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.073
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.071
dorsal ventral pattern formation GO:0009953 125 0.071
axis specification GO:0009798 43 0.071
apoptotic process GO:0006915 116 0.071
digestive system development GO:0055123 289 0.071
axon development GO:0061564 166 0.069
Fly
epidermis development GO:0008544 48 0.069
regulation of bmp signaling pathway GO:0030510 39 0.069
cellular component morphogenesis GO:0032989 336 0.068
Fly
response to light stimulus GO:0009416 46 0.067
response to fibroblast growth factor GO:0071774 22 0.067
regulation of neurogenesis GO:0050767 87 0.067
wound healing GO:0042060 90 0.066
cellular component assembly GO:0022607 170 0.066
Human
kidney development GO:0001822 92 0.066
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.066
myeloid cell homeostasis GO:0002262 56 0.066
steroid hormone mediated signaling pathway GO:0043401 9 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.065
Human Mouse Fly
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.065
negative regulation of multicellular organismal process GO:0051241 69 0.065
lateral line system development GO:0048925 76 0.065
skin development GO:0043588 54 0.064
somitogenesis GO:0001756 87 0.064
axon extension GO:0048675 45 0.063
specification of organ identity GO:0010092 2 0.063
regulation of cardiac muscle tissue development GO:0055024 1 0.063
macromolecule localization GO:0033036 54 0.063
sexual reproduction GO:0019953 36 0.062
Fly
regulation of cellular protein metabolic process GO:0032268 52 0.062
Mouse
epithelial cell differentiation GO:0030855 116 0.062
female sex differentiation GO:0046660 4 0.061
negative regulation of signaling GO:0023057 96 0.060
heart morphogenesis GO:0003007 156 0.059
positive regulation of map kinase activity GO:0043406 3 0.059
regulation of wnt signaling pathway GO:0030111 53 0.059
circadian sleep wake cycle sleep GO:0050802 1 0.059
anterior head development GO:0097065 2 0.058
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.057
regulation of programmed cell death GO:0043067 101 0.057
urogenital system development GO:0001655 97 0.055
positive regulation of transcription dna templated GO:0045893 57 0.055
Human Mouse Fly
cell projection morphogenesis GO:0048858 244 0.055
Fly
meiotic nuclear division GO:0007126 4 0.055
cell part morphogenesis GO:0032990 246 0.054
Fly
inner ear morphogenesis GO:0042472 63 0.054
phosphorylation GO:0016310 69 0.054
positive regulation of apoptotic signaling pathway GO:2001235 1 0.054
retina morphogenesis in camera type eye GO:0060042 79 0.053
glial cell differentiation GO:0010001 42 0.053
regulation of intracellular signal transduction GO:1902531 57 0.053
liver development GO:0001889 96 0.053
fin regeneration GO:0031101 51 0.052
embryonic skeletal system morphogenesis GO:0048704 93 0.052
sequestering of calcium ion GO:0051208 3 0.052
regulation of cell migration GO:0030334 40 0.051
regulation of apoptotic process GO:0042981 98 0.050
fertilization GO:0009566 3 0.050
ectodermal placode morphogenesis GO:0071697 32 0.050
cellular response to extracellular stimulus GO:0031668 2 0.050
stem cell proliferation GO:0072089 4 0.050
regulation of multicellular organismal development GO:2000026 223 0.050
bmp signaling pathway involved in heart development GO:0061312 15 0.050
renal system development GO:0072001 94 0.050
negative regulation of developmental process GO:0051093 65 0.050
positive regulation of cellular catabolic process GO:0031331 3 0.049
regulation of locomotion GO:0040012 55 0.049
regulation of nervous system development GO:0051960 90 0.049
positive regulation of catabolic process GO:0009896 4 0.049
atrioventricular valve formation GO:0003190 3 0.048
defense response GO:0006952 47 0.048
bmp signaling pathway involved in heart jogging GO:0003303 14 0.048
optic placode formation GO:0001743 4 0.047
positive regulation of multicellular organismal process GO:0051240 52 0.047
lipid storage GO:0019915 1 0.046
circadian sleep wake cycle GO:0042745 2 0.045
negative regulation of cell communication GO:0010648 96 0.045
hair cell differentiation GO:0035315 32 0.045
establishment of localization GO:0051234 244 0.045
Human
leukocyte differentiation GO:0002521 25 0.044
regulation of protein complex assembly GO:0043254 3 0.044
positive regulation of stem cell proliferation GO:2000648 1 0.043
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.042
developmental cell growth GO:0048588 52 0.042
regulation of cellular component movement GO:0051270 55 0.042
gamete generation GO:0007276 33 0.042
Fly
regulation of anterior head development GO:2000742 2 0.042
regulation of autophagy GO:0010506 3 0.041
cell death GO:0008219 121 0.041
regulation of erk1 and erk2 cascade GO:0070372 4 0.041
mesodermal cell differentiation GO:0048333 21 0.040
organelle organization GO:0006996 227 0.040
Human Mouse Fly
dorsal convergence GO:0060030 14 0.040
morphogenesis of embryonic epithelium GO:0016331 30 0.040
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.039
heart formation GO:0060914 13 0.039
cell proliferation involved in heart morphogenesis GO:0061323 2 0.039
specification of axis polarity GO:0065001 4 0.038
formation of primary germ layer GO:0001704 62 0.038
regulation of hormone levels GO:0010817 21 0.038
central nervous system neuron development GO:0021954 29 0.038
carbohydrate homeostasis GO:0033500 1 0.038
reproductive process GO:0022414 40 0.038
Fly
lymphocyte activation GO:0046649 10 0.037
regulation of axon extension GO:0030516 24 0.037
hepatocyte proliferation GO:0072574 2 0.037
embryonic pattern specification GO:0009880 44 0.037
regulation of neuron differentiation GO:0045664 56 0.036
cellular response to stress GO:0033554 62 0.036
Fly
gastrulation with mouth forming second GO:0001702 44 0.036
erk1 and erk2 cascade GO:0070371 4 0.036
developmental process involved in reproduction GO:0003006 27 0.035
pericardium development GO:0060039 1 0.035
positive regulation of muscle tissue development GO:1901863 1 0.035
response to nitrogen compound GO:1901698 19 0.035
heart jogging GO:0003146 40 0.035
ectoderm development GO:0007398 9 0.035
ovarian follicle development GO:0001541 2 0.035
exocytosis GO:0006887 1 0.034
cellular response to hormone stimulus GO:0032870 39 0.034
kidney morphogenesis GO:0060993 15 0.034
muscle fiber development GO:0048747 52 0.034
regulation of heart growth GO:0060420 2 0.034
positive regulation of signal transduction GO:0009967 56 0.034
nephron tubule morphogenesis GO:0072078 1 0.034
b cell activation GO:0042113 2 0.034
regulation of behavior GO:0050795 24 0.034
muscle cell differentiation GO:0042692 139 0.034
response to oxygen containing compound GO:1901700 55 0.033
foregut morphogenesis GO:0007440 4 0.033
adrenal gland development GO:0030325 10 0.033
regulation of stem cell differentiation GO:2000736 4 0.032
negative regulation of cell death GO:0060548 60 0.032
positive regulation of neural precursor cell proliferation GO:2000179 1 0.032
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.032
histone modification GO:0016570 20 0.032
Human Mouse Fly
embryonic digestive tract development GO:0048566 4 0.031
cell growth GO:0016049 57 0.031
cell migration GO:0016477 237 0.030
Fly
convergent extension GO:0060026 118 0.030
otic placode formation GO:0043049 23 0.030
larval development GO:0002164 2 0.030
skeletal muscle tissue development GO:0007519 67 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.030
cellular localization GO:0051641 97 0.030
innate immune response GO:0045087 13 0.030
hepatic duct development GO:0061011 2 0.030
regulation of localization GO:0032879 104 0.030
Human
negative regulation of apoptotic process GO:0043066 55 0.030
ectodermal placode formation GO:0060788 26 0.030
negative regulation of mesodermal cell fate specification GO:0042662 3 0.029
regulation of axonogenesis GO:0050770 32 0.029
hormone biosynthetic process GO:0042446 3 0.029
mitotic cell cycle GO:0000278 64 0.028
epithelial cell development GO:0002064 42 0.028
cellular protein metabolic process GO:0044267 129 0.028
Human Mouse Fly
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.028
forebrain regionalization GO:0021871 4 0.028
embryonic heart tube morphogenesis GO:0003143 108 0.028
positive regulation of alcohol biosynthetic process GO:1902932 1 0.028
regulation of cellular response to drug GO:2001038 1 0.028
Human
negative regulation of feeding behavior GO:2000252 2 0.027
cranial nerve development GO:0021545 42 0.027
response to dexamethasone GO:0071548 1 0.027
hormone mediated signaling pathway GO:0009755 9 0.027
regulation of receptor activity GO:0010469 2 0.027
hormone secretion GO:0046879 2 0.027
activation of mapk activity GO:0000187 3 0.027
gall bladder development GO:0061010 1 0.027
response to hormone GO:0009725 48 0.027
response to growth factor GO:0070848 39 0.027
positive regulation of protein metabolic process GO:0051247 23 0.026
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.025
mesodermal cell fate commitment GO:0001710 14 0.025
muscle tissue development GO:0060537 110 0.025
organophosphate metabolic process GO:0019637 37 0.025
cardiac cell fate commitment GO:0060911 1 0.025
autophagy GO:0006914 4 0.025
cellular response to growth factor stimulus GO:0071363 39 0.025
sequestering of metal ion GO:0051238 3 0.025
mesenchymal cell development GO:0014031 78 0.025
regulation of cell motility GO:2000145 46 0.025
cell migration involved in gastrulation GO:0042074 79 0.024
leukocyte activation GO:0045321 12 0.024
lymphocyte differentiation GO:0030098 9 0.024
positive regulation of cytokine production GO:0001819 2 0.024
forebrain generation of neurons GO:0021872 14 0.024
circadian rhythm GO:0007623 19 0.024
positive regulation of cell proliferation GO:0008284 15 0.024
determination of dorsal ventral asymmetry GO:0048262 34 0.023
methylation GO:0032259 22 0.023
Human Mouse Fly
regulation of gtp catabolic process GO:0033124 2 0.023
chromatin modification GO:0016568 21 0.023
Human Mouse Fly
cell adhesion GO:0007155 40 0.023
cerebellum development GO:0021549 17 0.023
muscle structure development GO:0061061 196 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.023
positive regulation of developmental process GO:0051094 50 0.023
mononuclear cell proliferation GO:0032943 1 0.023
arterial endothelial cell differentiation GO:0060842 2 0.023
thalamus development GO:0021794 6 0.022
cytosolic calcium ion transport GO:0060401 3 0.022
hepaticobiliary system development GO:0061008 98 0.022
death GO:0016265 121 0.022
regulation of phosphorylation GO:0042325 26 0.022
peptide transport GO:0015833 1 0.022
pronephros development GO:0048793 69 0.022
pigmentation GO:0043473 85 0.021
cell activation GO:0001775 16 0.021
positive regulation of striated muscle tissue development GO:0045844 1 0.021
macromolecular complex assembly GO:0065003 35 0.021
Human
hematopoietic progenitor cell differentiation GO:0002244 23 0.021
regulation of heart morphogenesis GO:2000826 17 0.021
stem cell differentiation GO:0048863 117 0.020
regulation of response to stress GO:0080134 36 0.020
Fly
cardiac muscle cell differentiation GO:0055007 30 0.020
regulation of response to external stimulus GO:0032101 31 0.020
glial cell migration GO:0008347 3 0.020
chemical homeostasis GO:0048878 49 0.020
lipid metabolic process GO:0006629 52 0.020
determination of left right asymmetry in nervous system GO:0035545 4 0.020
otic vesicle development GO:0071599 42 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
Human Mouse Fly
regulation of signal transduction by p53 class mediator GO:1901796 9 0.020
somatic muscle development GO:0007525 4 0.020
regulation of gene expression epigenetic GO:0040029 11 0.020
Mouse
renal tubule morphogenesis GO:0061333 1 0.020
reproductive structure development GO:0048608 5 0.020
cell cell signaling GO:0007267 52 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.019
response to abiotic stimulus GO:0009628 122 0.019
regulation of chondrocyte differentiation GO:0032330 1 0.019
cellular response to starvation GO:0009267 1 0.019
regulation of neurological system process GO:0031644 2 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
embryonic heart tube development GO:0035050 133 0.019
endoderm development GO:0007492 49 0.019
endocrine pancreas development GO:0031018 27 0.019

mll disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.218
bone development disease DOID:0080006 0 0.073
bone disease DOID:0080001 0 0.073
musculoskeletal system disease DOID:17 0 0.073
connective tissue disease DOID:65 0 0.073
osteochondrodysplasia DOID:2256 0 0.044
disease of cellular proliferation DOID:14566 0 0.029
pfeiffer syndrome DOID:14705 0 0.027
acrocephalosyndactylia DOID:12960 0 0.027
dysostosis DOID:1934 0 0.027
synostosis DOID:11971 0 0.027
cancer DOID:162 0 0.023
cleidocranial dysplasia DOID:13994 0 0.021