Danio rerio

0 known processes

mobkl2a

MOB1, Mps One Binder kinase activator-like 2A (yeast)

(Aliases: fc69e01,wu:fc69e01,zgc:56681,zgc:77552)

mobkl2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.208
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.115
regulation of developmental process GO:0050793 247 0.103
aging GO:0007568 2 0.094
signal transduction GO:0007165 455 0.093
negative regulation of biological process GO:0048519 304 0.091
tube morphogenesis GO:0035239 349 0.085
organelle organization GO:0006996 227 0.081
positive regulation of apoptotic signaling pathway GO:2001235 1 0.079
regulation of biological quality GO:0065008 263 0.079
immune system process GO:0002376 241 0.074
sensory organ development GO:0007423 393 0.071
heart development GO:0007507 313 0.063
mitochondrion organization GO:0007005 4 0.063
regulation of apoptotic process GO:0042981 98 0.062
locomotion GO:0040011 313 0.060
apoptotic process GO:0006915 116 0.058
cell surface receptor signaling pathway GO:0007166 325 0.055
cellular component biogenesis GO:0044085 178 0.055
blood vessel development GO:0001568 246 0.055
positive regulation of protein complex assembly GO:0031334 2 0.055
response to stress GO:0006950 263 0.055
extrinsic apoptotic signaling pathway GO:0097191 3 0.054
meiotic nuclear division GO:0007126 4 0.053
embryo development ending in birth or egg hatching GO:0009792 271 0.053
organelle fusion GO:0048284 3 0.053
meiotic cell cycle process GO:1903046 3 0.051
blood vessel morphogenesis GO:0048514 216 0.051
death GO:0016265 121 0.051
chordate embryonic development GO:0043009 271 0.050
response to other organism GO:0051707 97 0.049
regulation of programmed cell death GO:0043067 101 0.049
cell death GO:0008219 121 0.049
positive regulation of programmed cell death GO:0043068 29 0.049
vasculature development GO:0001944 278 0.048
single organism organelle organization GO:1902589 199 0.048
regulation of cellular component organization GO:0051128 86 0.047
regulation of reproductive process GO:2000241 4 0.047
regulation of response to stimulus GO:0048583 269 0.046
regulation of mitochondrion organization GO:0010821 1 0.045
morphogenesis of an epithelium GO:0002009 333 0.044
positive regulation of catabolic process GO:0009896 4 0.044
single organism membrane fusion GO:0044801 2 0.043
response to chemical GO:0042221 320 0.043
guanosine containing compound metabolic process GO:1901068 4 0.042
cellular response to nutrient levels GO:0031669 2 0.042
stem cell division GO:0017145 1 0.041
cytokinesis GO:0000910 3 0.041
programmed cell death GO:0012501 119 0.040
regulation of signal transduction GO:0009966 225 0.040
single organism metabolic process GO:0044710 217 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
signal transduction in absence of ligand GO:0038034 1 0.037
regulation of cell death GO:0010941 103 0.037
stem cell proliferation GO:0072089 4 0.037
stem cell maintenance GO:0019827 4 0.036
positive regulation of apoptotic process GO:0043065 29 0.035
phosphate containing compound metabolic process GO:0006796 108 0.035
negative regulation of reproductive process GO:2000242 3 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
positive regulation of transport GO:0051050 2 0.034
regulation of metabolic process GO:0019222 359 0.033
segmentation GO:0035282 97 0.033
guanosine containing compound catabolic process GO:1901069 2 0.032
protein metabolic process GO:0019538 183 0.032
phagocytosis GO:0006909 3 0.032
erk1 and erk2 cascade GO:0070371 4 0.032
positive regulation of cell death GO:0010942 29 0.032
nuclear transport GO:0051169 4 0.031
anterior posterior pattern specification GO:0009952 152 0.031
cellular component assembly GO:0022607 170 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
regulation of synapse organization GO:0050807 3 0.031
localization of cell GO:0051674 244 0.031
female sex differentiation GO:0046660 4 0.031
positive regulation of biological process GO:0048518 253 0.031
cortical actin cytoskeleton organization GO:0030866 1 0.031
regulation of signaling GO:0023051 235 0.030
response to external biotic stimulus GO:0043207 97 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
positive regulation of cell cycle GO:0045787 3 0.029
negative regulation of cellular process GO:0048523 283 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
regulation of protein complex assembly GO:0043254 3 0.029
compound eye development GO:0048749 2 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
organic substance biosynthetic process GO:1901576 289 0.028
growth GO:0040007 174 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
meiotic chromosome segregation GO:0045132 3 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
cellular response to extracellular stimulus GO:0031668 2 0.027
cellular response to external stimulus GO:0071496 2 0.027
response to external stimulus GO:0009605 264 0.027
regulation of cell communication GO:0010646 232 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
regulation of meiotic cell cycle GO:0051445 1 0.026
regulation of protein catabolic process GO:0042176 1 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
golgi vesicle transport GO:0048193 3 0.026
transport GO:0006810 220 0.026
single organism transport GO:0044765 206 0.025
regionalization GO:0003002 274 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
response to bacterium GO:0009617 58 0.025
female gonad development GO:0008585 4 0.025
head development GO:0060322 303 0.024
positive regulation of metabolic process GO:0009893 108 0.024
cellular protein metabolic process GO:0044267 129 0.024
hemopoiesis GO:0030097 183 0.024
response to abiotic stimulus GO:0009628 122 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
negative regulation of kinase activity GO:0033673 4 0.024
regulation of cell activation GO:0050865 1 0.024
lipid storage GO:0019915 1 0.023
adult behavior GO:0030534 2 0.023
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
gtp metabolic process GO:0046039 4 0.023
gene expression GO:0010467 252 0.023
gtp catabolic process GO:0006184 2 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
phosphorus metabolic process GO:0006793 109 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
regulation of primary metabolic process GO:0080090 311 0.023
cellular component movement GO:0006928 335 0.022
protein dephosphorylation GO:0006470 3 0.022
nuclear import GO:0051170 3 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
intracellular signal transduction GO:0035556 85 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
negative regulation of protein kinase activity GO:0006469 4 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of cell shape GO:0008360 1 0.021
multicellular organism growth GO:0035264 4 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
eye development GO:0001654 277 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
regulation of oocyte development GO:0060281 3 0.021
regulation of dendrite development GO:0050773 3 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
embryonic organ development GO:0048568 381 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
immune system development GO:0002520 191 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.020
apoptotic signaling pathway GO:0097190 23 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
neurotransmitter transport GO:0006836 2 0.020
maintenance of location GO:0051235 4 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
neuron differentiation GO:0030182 353 0.020
autophagy GO:0006914 4 0.020
regulation of molecular function GO:0065009 70 0.020
multi organism process GO:0051704 134 0.019
cell motility GO:0048870 244 0.019
somite development GO:0061053 96 0.019
regulation of synapse assembly GO:0051963 3 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
membrane fusion GO:0061025 2 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
odontogenesis of dentin containing tooth GO:0042475 1 0.019
neuroblast proliferation GO:0007405 2 0.019
regulation of mrna processing GO:0050684 3 0.019
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of gene expression GO:0010468 265 0.019
cellular respiration GO:0045333 3 0.019
negative regulation of epithelial cell proliferation GO:0050680 1 0.018
negative regulation of signal transduction GO:0009968 94 0.018
cellular protein catabolic process GO:0044257 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
protein heterooligomerization GO:0051291 1 0.018
convergent extension GO:0060026 118 0.018
cellular amine metabolic process GO:0044106 2 0.018
response to organic substance GO:0010033 153 0.018
negative regulation of nuclear division GO:0051784 3 0.018
cognition GO:0050890 1 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
cellular response to starvation GO:0009267 1 0.018
response to biotic stimulus GO:0009607 97 0.018
secondary metabolic process GO:0019748 3 0.018
response to glucose GO:0009749 3 0.018
heart morphogenesis GO:0003007 156 0.018
homeostatic process GO:0042592 142 0.018
digestive tract development GO:0048565 265 0.018
regulation of multicellular organismal development GO:2000026 223 0.017
cellular biosynthetic process GO:0044249 286 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
positive regulation of hydrolase activity GO:0051345 13 0.017
mononuclear cell proliferation GO:0032943 1 0.017
cell proliferation GO:0008283 80 0.017
response to monosaccharide GO:0034284 3 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
response to hexose GO:0009746 3 0.017
positive regulation of cellular process GO:0048522 201 0.017
synaptic vesicle transport GO:0048489 1 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
ameboidal type cell migration GO:0001667 143 0.017
cellular amino acid metabolic process GO:0006520 7 0.016
b cell differentiation GO:0030183 1 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
germ line stem cell maintenance GO:0030718 2 0.016
biosynthetic process GO:0009058 294 0.016
regulation of cell size GO:0008361 29 0.016
ovulation cycle process GO:0022602 2 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
digestive system development GO:0055123 289 0.016
gastrulation GO:0007369 208 0.016
regulation of cytokine production GO:0001817 3 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
macroautophagy GO:0016236 1 0.016
chemosensory behavior GO:0007635 1 0.015
establishment or maintenance of cell polarity GO:0007163 29 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
negative regulation of mitosis GO:0045839 3 0.015
developmental growth GO:0048589 166 0.015
cellular ketone metabolic process GO:0042180 11 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
protein polymerization GO:0051258 4 0.015
cellular component disassembly GO:0022411 1 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of autophagy GO:0010506 3 0.015
lateral inhibition GO:0046331 1 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
amine metabolic process GO:0009308 2 0.015
protein import into nucleus GO:0006606 3 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
urogenital system development GO:0001655 97 0.015
kidney development GO:0001822 92 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
response to corticosteroid GO:0031960 1 0.014
cilium morphogenesis GO:0060271 85 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
negative regulation of defense response GO:0031348 2 0.014
cytokinetic process GO:0032506 2 0.014
regulation of gtpase activity GO:0043087 2 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
somitogenesis GO:0001756 87 0.014
macromolecule modification GO:0043412 111 0.014
synaptic vesicle endocytosis GO:0048488 1 0.014
negative regulation of cell communication GO:0010648 96 0.014
regulation of membrane potential GO:0042391 23 0.014
establishment of localization GO:0051234 244 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of apoptotic signaling pathway GO:2001233 12 0.014
regulation of cell morphogenesis GO:0022604 42 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
rna localization GO:0006403 4 0.014
response to nutrient GO:0007584 3 0.014
regulation of catalytic activity GO:0050790 55 0.014
heterocycle metabolic process GO:0046483 290 0.014
regulation of organ growth GO:0046620 3 0.014
cellular localization GO:0051641 97 0.014
generation of neurons GO:0048699 385 0.014
lymphocyte proliferation GO:0046651 1 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
meiosis i GO:0007127 1 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
defense response to other organism GO:0098542 33 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
system process GO:0003008 185 0.013
neurotransmitter secretion GO:0007269 2 0.013
single organism localization GO:1902578 225 0.013
regulation of blood pressure GO:0008217 1 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
cellular response to oxygen levels GO:0071453 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
positive regulation of catalytic activity GO:0043085 25 0.013
somatic muscle development GO:0007525 4 0.013
organic acid metabolic process GO:0006082 31 0.013
ovulation cycle GO:0042698 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
response to glucocorticoid GO:0051384 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of anatomical structure size GO:0090066 33 0.013
positive regulation of neuron death GO:1901216 1 0.013
leukocyte proliferation GO:0070661 1 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
negative regulation of immune response GO:0050777 2 0.013
cell morphogenesis GO:0000902 289 0.012
regulation of blood vessel size GO:0050880 2 0.012
establishment of localization in cell GO:0051649 77 0.012
lipid homeostasis GO:0055088 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
sequestering of metal ion GO:0051238 3 0.012
innate immune response GO:0045087 13 0.012
protein stabilization GO:0050821 2 0.012
somatic stem cell maintenance GO:0035019 1 0.012
response to carbohydrate GO:0009743 3 0.012
defense response to bacterium GO:0042742 22 0.012
neurological system process GO:0050877 62 0.012
cellular aldehyde metabolic process GO:0006081 4 0.012
regulation of hydrolase activity GO:0051336 28 0.012
positive regulation of camp biosynthetic process GO:0030819 2 0.012
hormone secretion GO:0046879 2 0.012
regulation of hormone secretion GO:0046883 2 0.012
regulation of dna replication GO:0006275 3 0.012
exocytosis GO:0006887 1 0.012
calcium mediated signaling GO:0019722 2 0.012
camera type eye development GO:0043010 222 0.012
regulation of cellular component size GO:0032535 30 0.012
sequestering of calcium ion GO:0051208 3 0.012
activation of mapk activity GO:0000187 3 0.012
sensory organ morphogenesis GO:0090596 200 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of inflammatory response GO:0050727 2 0.012
cellular protein modification process GO:0006464 100 0.012
apical junction assembly GO:0043297 1 0.012
response to amine GO:0014075 1 0.012
intracellular mrna localization GO:0008298 1 0.012
glial cell migration GO:0008347 3 0.012
response to endogenous stimulus GO:0009719 83 0.012
regulation of cell projection assembly GO:0060491 4 0.012
glucose homeostasis GO:0042593 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
post embryonic organ development GO:0048569 4 0.012
atp catabolic process GO:0006200 4 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
response to topologically incorrect protein GO:0035966 2 0.011
negative regulation of cell death GO:0060548 60 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
positive regulation of cell communication GO:0010647 56 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
b cell activation GO:0042113 2 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
angiogenesis GO:0001525 158 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
cell cycle arrest GO:0007050 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
rna metabolic process GO:0016070 219 0.011
protein localization to microtubule cytoskeleton GO:0072698 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
multicellular organismal response to stress GO:0033555 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
digestive tract morphogenesis GO:0048546 231 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
hormone transport GO:0009914 2 0.011
protein polyubiquitination GO:0000209 4 0.011
cell projection morphogenesis GO:0048858 244 0.011
synaptic vesicle recycling GO:0036465 1 0.011
branching morphogenesis of an epithelial tube GO:0048754 15 0.011
post embryonic morphogenesis GO:0009886 4 0.011
negative regulation of dna replication GO:0008156 2 0.011
defense response GO:0006952 47 0.011
regulation of protein metabolic process GO:0051246 56 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
regulation of protein transport GO:0051223 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
ovarian follicle development GO:0001541 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
renal tubule morphogenesis GO:0061333 1 0.011
single organism membrane organization GO:0044802 20 0.011
skeletal system morphogenesis GO:0048705 102 0.011
cytoskeleton organization GO:0007010 96 0.011
regulation of peptidase activity GO:0052547 23 0.011
microtubule based process GO:0007017 60 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
cell cycle GO:0007049 93 0.010
cell part morphogenesis GO:0032990 246 0.010
cilium organization GO:0044782 71 0.010
pole plasm assembly GO:0007315 4 0.010
oxoacid metabolic process GO:0043436 31 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
fertilization GO:0009566 3 0.010
entrainment of circadian clock GO:0009649 2 0.010
cell cycle process GO:0022402 53 0.010
mitotic cell cycle GO:0000278 64 0.010
myeloid cell homeostasis GO:0002262 56 0.010
regulation of tube size GO:0035150 2 0.010

mobkl2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.013