Danio rerio

0 known processes

msrb3

methionine sulfoxide reductase B3

(Aliases: wu:fc07g04,zgc:86909)

msrb3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.163
organic cyclic compound metabolic process GO:1901360 301 0.130
cellular biosynthetic process GO:0044249 286 0.121
larval development GO:0002164 2 0.116
cellular macromolecule metabolic process GO:0044260 391 0.112
maintenance of location GO:0051235 4 0.101
regulation of multicellular organism growth GO:0040014 4 0.100
signal transduction GO:0007165 455 0.099
regulation of biological quality GO:0065008 263 0.099
locomotion GO:0040011 313 0.098
nitrogen compound metabolic process GO:0006807 319 0.096
positive regulation of biological process GO:0048518 253 0.096
regulation of developmental process GO:0050793 247 0.094
regulation of signaling GO:0023051 235 0.087
organic substance biosynthetic process GO:1901576 289 0.086
single organism metabolic process GO:0044710 217 0.082
aging GO:0007568 2 0.081
multicellular organism growth GO:0035264 4 0.077
transmembrane transport GO:0055085 120 0.076
heterocycle metabolic process GO:0046483 290 0.075
cellular nitrogen compound metabolic process GO:0034641 290 0.073
spermatid development GO:0007286 2 0.071
cellular macromolecule biosynthetic process GO:0034645 224 0.069
cellular nitrogen compound biosynthetic process GO:0044271 218 0.069
regulation of multicellular organismal process GO:0051239 277 0.069
regulation of gene expression GO:0010468 265 0.069
establishment of localization GO:0051234 244 0.065
regulation of response to stimulus GO:0048583 269 0.064
biosynthetic process GO:0009058 294 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.063
spermatid differentiation GO:0048515 2 0.062
macromolecule biosynthetic process GO:0009059 227 0.059
single organism localization GO:1902578 225 0.057
nucleobase containing compound metabolic process GO:0006139 274 0.055
regulation of cell communication GO:0010646 232 0.055
mitochondrion organization GO:0007005 4 0.053
pyruvate metabolic process GO:0006090 1 0.053
organic cyclic compound biosynthetic process GO:1901362 223 0.053
lipid storage GO:0019915 1 0.051
immune system process GO:0002376 241 0.050
nucleic acid metabolic process GO:0090304 244 0.049
growth GO:0040007 174 0.049
transport GO:0006810 220 0.049
nucleobase containing compound biosynthetic process GO:0034654 205 0.048
regulation of cell shape GO:0008360 1 0.047
response to external stimulus GO:0009605 264 0.044
phagocytosis GO:0006909 3 0.043
regulation of cellular metabolic process GO:0031323 320 0.043
aromatic compound biosynthetic process GO:0019438 217 0.043
gene expression GO:0010467 252 0.042
organic acid metabolic process GO:0006082 31 0.039
death GO:0016265 121 0.038
regulation of nucleoside metabolic process GO:0009118 2 0.038
positive regulation of cellular process GO:0048522 201 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.036
protein polymerization GO:0051258 4 0.035
multi organism process GO:0051704 134 0.035
meiotic nuclear division GO:0007126 4 0.034
modification dependent macromolecule catabolic process GO:0043632 3 0.033
single organism transport GO:0044765 206 0.033
regulation of blood pressure GO:0008217 1 0.033
regulation of signal transduction GO:0009966 225 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
intracellular signal transduction GO:0035556 85 0.033
embryonic organ development GO:0048568 381 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
heart development GO:0007507 313 0.032
system process GO:0003008 185 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
cellular component morphogenesis GO:0032989 336 0.032
lateral inhibition GO:0046331 1 0.032
response to stress GO:0006950 263 0.032
response to chemical GO:0042221 320 0.032
nucleic acid templated transcription GO:0097659 181 0.032
gtp catabolic process GO:0006184 2 0.031
g1 s transition of mitotic cell cycle GO:0000082 1 0.031
localization of cell GO:0051674 244 0.031
positive regulation of transport GO:0051050 2 0.030
cell projection organization GO:0030030 284 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
small molecule metabolic process GO:0044281 77 0.030
cellular component movement GO:0006928 335 0.030
organelle organization GO:0006996 227 0.030
liver development GO:0001889 96 0.030
gtp metabolic process GO:0046039 4 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
digestive tract development GO:0048565 265 0.029
protein import into nucleus GO:0006606 3 0.029
neurotransmitter transport GO:0006836 2 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
protein metabolic process GO:0019538 183 0.028
cation transmembrane transport GO:0098655 65 0.028
stem cell proliferation GO:0072089 4 0.028
regulation of metal ion transport GO:0010959 4 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.027
protein localization to nucleus GO:0034504 3 0.027
regulation of primary metabolic process GO:0080090 311 0.027
response to nutrient GO:0007584 3 0.027
regulation of cell projection assembly GO:0060491 4 0.027
transcription dna templated GO:0006351 181 0.027
positive regulation of catabolic process GO:0009896 4 0.027
hepaticobiliary system development GO:0061008 98 0.027
regulation of membrane potential GO:0042391 23 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
alpha amino acid metabolic process GO:1901605 3 0.026
positive regulation of metabolic process GO:0009893 108 0.026
cellular component biogenesis GO:0044085 178 0.026
cellular localization GO:0051641 97 0.026
cellular response to external stimulus GO:0071496 2 0.026
regulation of circadian rhythm GO:0042752 4 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
regulation of neurotransmitter transport GO:0051588 1 0.025
negative regulation of cellular process GO:0048523 283 0.025
cellular component disassembly GO:0022411 1 0.025
amine metabolic process GO:0009308 2 0.024
neurotransmitter secretion GO:0007269 2 0.024
wound healing GO:0042060 90 0.024
ion transport GO:0006811 114 0.023
determination of bilateral symmetry GO:0009855 204 0.023
positive regulation of gene expression GO:0010628 71 0.023
regulation of biosynthetic process GO:0009889 250 0.023
programmed cell death GO:0012501 119 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
rna metabolic process GO:0016070 219 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
regulation of cell activation GO:0050865 1 0.023
regulation of cell substrate adhesion GO:0010810 1 0.023
cardiac atrium development GO:0003230 4 0.023
regulation of ion transmembrane transporter activity GO:0032412 2 0.022
negative regulation of biological process GO:0048519 304 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
positive regulation of response to stimulus GO:0048584 80 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
single organism organelle organization GO:1902589 199 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of systemic arterial blood pressure GO:0003073 1 0.021
atp catabolic process GO:0006200 4 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
nuclear import GO:0051170 3 0.021
regulation of tube size GO:0035150 2 0.021
hormone secretion GO:0046879 2 0.021
regulation of synapse assembly GO:0051963 3 0.021
stem cell maintenance GO:0019827 4 0.021
homeostatic process GO:0042592 142 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
guanosine containing compound metabolic process GO:1901068 4 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
hormone transport GO:0009914 2 0.020
response to drug GO:0042493 3 0.020
cell motility GO:0048870 244 0.020
oxoacid metabolic process GO:0043436 31 0.020
cation transport GO:0006812 81 0.020
specification of symmetry GO:0009799 204 0.020
regulation of neurotransmitter secretion GO:0046928 1 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
regulation of hormone secretion GO:0046883 2 0.020
developmental growth GO:0048589 166 0.019
cell morphogenesis GO:0000902 289 0.019
cellular protein catabolic process GO:0044257 4 0.019
cellular protein metabolic process GO:0044267 129 0.019
protein complex disassembly GO:0043241 1 0.019
positive regulation of cell activation GO:0050867 1 0.019
single organism nuclear import GO:1902593 3 0.019
small molecule catabolic process GO:0044282 3 0.019
cellular response to nutrient levels GO:0031669 2 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
regulation of blood vessel size GO:0050880 2 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.018
immune system development GO:0002520 191 0.018
dicarboxylic acid metabolic process GO:0043648 1 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
behavior GO:0007610 74 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
gastrulation GO:0007369 208 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
regulation of rna metabolic process GO:0051252 224 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
cellular ketone metabolic process GO:0042180 11 0.018
cellular response to xenobiotic stimulus GO:0071466 35 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
nuclear transport GO:0051169 4 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
organelle localization GO:0051640 49 0.018
organic substance transport GO:0071702 58 0.018
cell migration GO:0016477 237 0.017
membrane fusion GO:0061025 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
response to organic substance GO:0010033 153 0.017
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.017
response to corticosteroid GO:0031960 1 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
digestive tract morphogenesis GO:0048546 231 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
regulation of binding GO:0051098 3 0.017
cell part morphogenesis GO:0032990 246 0.017
blood circulation GO:0008015 87 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
establishment of localization in cell GO:0051649 77 0.017
protein import GO:0017038 3 0.017
response to wounding GO:0009611 116 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
neurological system process GO:0050877 62 0.017
cellular amine metabolic process GO:0044106 2 0.017
cell substrate adhesion GO:0031589 4 0.017
release of sequestered calcium ion into cytosol GO:0051209 3 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
rna biosynthetic process GO:0032774 181 0.016
actin filament polymerization GO:0030041 2 0.016
negative regulation of cell differentiation GO:0045596 46 0.016
centrosome organization GO:0051297 1 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
macromolecular complex disassembly GO:0032984 1 0.016
macromolecule modification GO:0043412 111 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
regulation of protein polymerization GO:0032271 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
positive regulation of notch signaling pathway GO:0045747 3 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
regulation of cell death GO:0010941 103 0.015
regulation of synapse organization GO:0050807 3 0.015
immune response GO:0006955 28 0.015
regulation of transporter activity GO:0032409 2 0.015
ion transmembrane transport GO:0034220 91 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
inorganic cation transmembrane transport GO:0098662 50 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
central nervous system development GO:0007417 387 0.015
regulation of protein complex assembly GO:0043254 3 0.015
b cell activation GO:0042113 2 0.015
gland development GO:0048732 143 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
cellular respiration GO:0045333 3 0.015
regulation of molecular function GO:0065009 70 0.015
cell projection morphogenesis GO:0048858 244 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
digestive system development GO:0055123 289 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
locomotor rhythm GO:0045475 3 0.014
actin filament based movement GO:0030048 1 0.014
phagocytosis engulfment GO:0006911 1 0.014
oxidation reduction process GO:0055114 41 0.014
determination of left right symmetry GO:0007368 179 0.014
cellular modified amino acid metabolic process GO:0006575 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
cardiac chamber formation GO:0003207 4 0.014
response to ketone GO:1901654 1 0.014
cellular amide metabolic process GO:0043603 4 0.014
regionalization GO:0003002 274 0.014
regulation of reproductive process GO:2000241 4 0.014
neuron differentiation GO:0030182 353 0.014
regulation of calcium ion transport GO:0051924 2 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
organic acid catabolic process GO:0016054 3 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
transmission of nerve impulse GO:0019226 19 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of developmental growth GO:0048638 38 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
blood vessel morphogenesis GO:0048514 216 0.013
tube morphogenesis GO:0035239 349 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
response to monosaccharide GO:0034284 3 0.013
plasma membrane repair GO:0001778 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
branched chain amino acid metabolic process GO:0009081 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
regulation of programmed cell death GO:0043067 101 0.013
apoptotic process GO:0006915 116 0.013
neuron projection morphogenesis GO:0048812 161 0.013
generation of neurons GO:0048699 385 0.013
lamellipodium organization GO:0097581 1 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of localization GO:0032879 104 0.013
cell aging GO:0007569 2 0.013
phosphorylation GO:0016310 69 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
single organism biosynthetic process GO:0044711 71 0.013
nucleic acid transport GO:0050657 2 0.013
response to hexose GO:0009746 3 0.013
cell death GO:0008219 121 0.013
positive regulation of secretion GO:0051047 1 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
connective tissue development GO:0061448 99 0.013
membrane invagination GO:0010324 1 0.013
regulation of cellular component organization GO:0051128 86 0.013
negative regulation of signaling GO:0023057 96 0.013
response to unfolded protein GO:0006986 2 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
regulation of growth GO:0040008 42 0.013
cell cell signaling GO:0007267 52 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of establishment of protein localization GO:0070201 4 0.012
adult behavior GO:0030534 2 0.012
response to glucose GO:0009749 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
embryonic heart tube development GO:0035050 133 0.012
tissue remodeling GO:0048771 4 0.012
autophagy GO:0006914 4 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
mitochondrial transport GO:0006839 2 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
entrainment of circadian clock GO:0009649 2 0.012
astrocyte differentiation GO:0048708 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
response to topologically incorrect protein GO:0035966 2 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular component assembly GO:0022607 170 0.012
lipid homeostasis GO:0055088 3 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
glucose homeostasis GO:0042593 1 0.012
sequestering of metal ion GO:0051238 3 0.012
cellular catabolic process GO:0044248 27 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
glial cell migration GO:0008347 3 0.012
peptide metabolic process GO:0006518 1 0.012
mechanosensory behavior GO:0007638 2 0.011
germ line stem cell maintenance GO:0030718 2 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
protein homooligomerization GO:0051260 3 0.011
renal system development GO:0072001 94 0.011
peptidyl serine modification GO:0018209 2 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of receptor activity GO:0010469 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
metal ion transport GO:0030001 58 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
head development GO:0060322 303 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
cognition GO:0050890 1 0.011
regulation of wound healing GO:0061041 2 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
cellular protein modification process GO:0006464 100 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
neuronal action potential GO:0019228 18 0.011
neuron development GO:0048666 262 0.011
regulation of mrna processing GO:0050684 3 0.011
circulatory system process GO:0003013 87 0.011
chordate embryonic development GO:0043009 271 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
muscle cell development GO:0055001 115 0.011
peptide transport GO:0015833 1 0.011
response to hormone GO:0009725 48 0.011
regulation of filopodium assembly GO:0051489 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
lipid catabolic process GO:0016042 4 0.011
methylation GO:0032259 22 0.011
mesoderm development GO:0007498 88 0.011
rna localization GO:0006403 4 0.011
calcium mediated signaling GO:0019722 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
positive regulation of cell communication GO:0010647 56 0.010
neuroblast proliferation GO:0007405 2 0.010
amino acid transport GO:0006865 2 0.010
negative regulation of blood circulation GO:1903523 2 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
meiotic cell cycle process GO:1903046 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010
cellular response to stress GO:0033554 62 0.010
regeneration GO:0031099 91 0.010
sequestering of calcium ion GO:0051208 3 0.010
lymphocyte proliferation GO:0046651 1 0.010
regulation of protein transport GO:0051223 3 0.010
cytokinesis GO:0000910 3 0.010
negative regulation of kinase activity GO:0033673 4 0.010
response to alkaloid GO:0043279 2 0.010
smooth muscle contraction GO:0006939 2 0.010
chondrocyte development GO:0002063 4 0.010

msrb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.018
disease of anatomical entity DOID:7 0 0.018
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.016
musculoskeletal system disease DOID:17 0 0.015
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
nervous system disease DOID:863 0 0.011