Danio rerio

0 known processes

mthfd2

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

(Aliases: MGC91891,zgc:91891,MGC174756,wu:fe12e11,wu:fb38b11)

mthfd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular modified amino acid metabolic process GO:0006575 3 0.112
epithelial tube morphogenesis GO:0060562 148 0.090
organonitrogen compound biosynthetic process GO:1901566 47 0.087
pyrimidine containing compound metabolic process GO:0072527 3 0.058
single organism transport GO:0044765 206 0.055
small molecule biosynthetic process GO:0044283 16 0.047
larval development GO:0002164 2 0.043
negative regulation of protein localization to nucleus GO:1900181 2 0.043
ion transport GO:0006811 114 0.043
single organism localization GO:1902578 225 0.041
cellular amino acid biosynthetic process GO:0008652 2 0.040
organic acid metabolic process GO:0006082 31 0.038
maintenance of location GO:0051235 4 0.035
multicellular organism growth GO:0035264 4 0.034
regulation of multicellular organism growth GO:0040014 4 0.033
carboxylic acid metabolic process GO:0019752 22 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
tube morphogenesis GO:0035239 349 0.029
regulation of skeletal muscle fiber development GO:0048742 2 0.029
striated muscle tissue development GO:0014706 110 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
aging GO:0007568 2 0.028
protein import GO:0017038 3 0.028
establishment of localization GO:0051234 244 0.027
embryonic organ development GO:0048568 381 0.026
rna localization GO:0006403 4 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
transport GO:0006810 220 0.023
cellular localization GO:0051641 97 0.023
protein localization to nucleus GO:0034504 3 0.023
regulation of reproductive process GO:2000241 4 0.023
nucleobase containing compound transport GO:0015931 2 0.022
amine metabolic process GO:0009308 2 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
cellular amine metabolic process GO:0044106 2 0.021
adult behavior GO:0030534 2 0.021
regulation of synapse organization GO:0050807 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
sensory organ development GO:0007423 393 0.021
embryonic organ morphogenesis GO:0048562 274 0.020
lipid storage GO:0019915 1 0.020
biosynthetic process GO:0009058 294 0.020
nuclear transport GO:0051169 4 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
head development GO:0060322 303 0.020
digestive system development GO:0055123 289 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
cellular component movement GO:0006928 335 0.019
digestive tract development GO:0048565 265 0.019
negative regulation of kinase activity GO:0033673 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
stem cell proliferation GO:0072089 4 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of cytokine production GO:0001817 3 0.018
brain development GO:0007420 293 0.018
protein targeting to nucleus GO:0044744 3 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
chordate embryonic development GO:0043009 271 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of biological quality GO:0065008 263 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
camera type eye development GO:0043010 222 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
cell part morphogenesis GO:0032990 246 0.017
cellular ketone metabolic process GO:0042180 11 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of metal ion transport GO:0010959 4 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
posttranscriptional gene silencing by rna GO:0035194 3 0.016
localization of cell GO:0051674 244 0.016
small molecule metabolic process GO:0044281 77 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
adherens junction organization GO:0034332 4 0.016
regulation of dendrite development GO:0050773 3 0.016
nuclear import GO:0051170 3 0.016
regionalization GO:0003002 274 0.016
cellular biosynthetic process GO:0044249 286 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
cellular response to external stimulus GO:0071496 2 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
negative regulation of biological process GO:0048519 304 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
negative regulation of map kinase activity GO:0043407 2 0.014
morphogenesis of embryonic epithelium GO:0016331 30 0.014
regulation of protein transport GO:0051223 3 0.014
protein import into nucleus GO:0006606 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of catabolic process GO:0009896 4 0.014
heart development GO:0007507 313 0.014
muscle structure development GO:0061061 196 0.014
stem cell maintenance GO:0019827 4 0.013
phagocytosis GO:0006909 3 0.013
retina development in camera type eye GO:0060041 146 0.013
single organism nuclear import GO:1902593 3 0.013
cellular protein catabolic process GO:0044257 4 0.013
gtp metabolic process GO:0046039 4 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
central nervous system development GO:0007417 387 0.013
specification of symmetry GO:0009799 204 0.013
gtp catabolic process GO:0006184 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
membrane invagination GO:0010324 1 0.013
regulation of myotube differentiation GO:0010830 2 0.013
regulation of multicellular organismal process GO:0051239 277 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
convergent extension GO:0060026 118 0.012
eye development GO:0001654 277 0.012
gastrulation GO:0007369 208 0.012
muscle cell development GO:0055001 115 0.012
regulation of cell shape GO:0008360 1 0.012
single organism metabolic process GO:0044710 217 0.012
regulation of binding GO:0051098 3 0.012
exocytosis GO:0006887 1 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
microtubule organizing center organization GO:0031023 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of oocyte development GO:0060281 3 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
striated muscle cell differentiation GO:0051146 129 0.011
heart morphogenesis GO:0003007 156 0.011
cell motility GO:0048870 244 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
cell migration GO:0016477 237 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cell substrate adhesion GO:0031589 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
striated muscle cell development GO:0055002 108 0.011
establishment of rna localization GO:0051236 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
locomotion GO:0040011 313 0.011
leukocyte proliferation GO:0070661 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
tube closure GO:0060606 1 0.011
regulation of protein targeting GO:1903533 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
neuronal action potential GO:0019228 18 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
endosomal transport GO:0016197 2 0.010
interspecies interaction between organisms GO:0044419 4 0.010
muscle fiber development GO:0048747 52 0.010
deoxyribose phosphate metabolic process GO:0019692 1 0.010
rna transport GO:0050658 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of cell activation GO:0050865 1 0.010
response to amino acid GO:0043200 2 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
regulation of gtpase activity GO:0043087 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010

mthfd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
immune system disease DOID:2914 0 0.011
musculoskeletal system disease DOID:17 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010