Danio rerio

0 known processes

myhc4

myosin heavy chain 4

(Aliases: wu:fi38g05,wu:fi17f08,fi38g05)

myhc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
voluntary skeletal muscle contraction GO:0003010 4 0.911
Zebrafish
twitch skeletal muscle contraction GO:0014721 4 0.819
Zebrafish
skeletal myofibril assembly GO:0014866 7 0.774
Zebrafish Mouse Worm Fly
skeletal muscle contraction GO:0003009 5 0.583
Zebrafish
larval development GO:0002164 2 0.465
Worm
regulation of sarcomere organization GO:0060297 2 0.449
Mouse
multicellular organismal movement GO:0050879 8 0.429
Zebrafish
regulation of organelle assembly GO:1902115 4 0.394
Mouse
neuron development GO:0048666 262 0.375
Worm
striated muscle cell differentiation GO:0051146 129 0.344
Zebrafish Mouse Worm Fly
skeletal muscle thin filament assembly GO:0030240 4 0.328
Zebrafish
striated muscle myosin thick filament assembly GO:0071688 6 0.303
Zebrafish Mouse Worm Fly
skeletal muscle fiber development GO:0048741 35 0.303
Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.287
Zebrafish Mouse Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.267
Fly
regulation of primary metabolic process GO:0080090 311 0.250
regulation of metabolic process GO:0019222 359 0.232
Fly
skeletal muscle myosin thick filament assembly GO:0030241 5 0.227
Mouse Worm Fly
cellular aromatic compound metabolic process GO:0006725 295 0.192
Fly
skeletal muscle organ development GO:0060538 78 0.191
Zebrafish Mouse
somatic muscle development GO:0007525 4 0.178
Fly
epithelial tube morphogenesis GO:0060562 148 0.173
cell projection organization GO:0030030 284 0.172
Worm
musculoskeletal movement GO:0050881 8 0.159
Zebrafish
regulation of biological quality GO:0065008 263 0.156
Fly
striated muscle tissue development GO:0014706 110 0.151
Zebrafish Mouse
neuron projection development GO:0031175 180 0.148
Worm
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.143
Zebrafish
locomotion GO:0040011 313 0.136
Worm Fly
neuron differentiation GO:0030182 353 0.136
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.134
Fly
cellular biosynthetic process GO:0044249 286 0.129
organic substance biosynthetic process GO:1901576 289 0.125
signal transduction GO:0007165 455 0.125
Worm
mitochondrion organization GO:0007005 4 0.117
regulation of gene expression GO:0010468 265 0.116
Fly
reactive nitrogen species metabolic process GO:2001057 0 0.115
generation of neurons GO:0048699 385 0.115
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.113
muscle fiber development GO:0048747 52 0.108
Zebrafish Mouse
regulation of muscle contraction GO:0006937 3 0.102
cellular component morphogenesis GO:0032989 336 0.100
Zebrafish Mouse Worm Fly
nephron morphogenesis GO:0072028 2 0.099
regionalization GO:0003002 274 0.098
Zebrafish
muscle system process GO:0003012 20 0.097
Zebrafish Worm Fly
somite development GO:0061053 96 0.093
Zebrafish
muscle organ development GO:0007517 101 0.085
Zebrafish Mouse Fly
inositol lipid mediated signaling GO:0048017 2 0.081
Worm
biosynthetic process GO:0009058 294 0.079
somitogenesis GO:0001756 87 0.078
Zebrafish
somite specification GO:0001757 12 0.078
Zebrafish
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.075
Fly
vasculature development GO:0001944 278 0.073
purine ribonucleotide metabolic process GO:0009150 27 0.073
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.072
specification of organ identity GO:0010092 2 0.072
cell part morphogenesis GO:0032990 246 0.069
protein stabilization GO:0050821 2 0.069
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.068
Fly
reproduction GO:0000003 40 0.068
Worm Fly
system process GO:0003008 185 0.068
Zebrafish Worm Fly
regulation of myotube differentiation GO:0010830 2 0.068
embryonic heart tube development GO:0035050 133 0.068
atp catabolic process GO:0006200 4 0.068
Fly
regulation of metal ion transport GO:0010959 4 0.067
segmentation GO:0035282 97 0.067
Zebrafish
cell migration GO:0016477 237 0.066
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.063
Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.062
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.062
purine nucleoside monophosphate catabolic process GO:0009128 4 0.060
Fly
muscle tissue development GO:0060537 110 0.059
Zebrafish Mouse
cytokinesis GO:0000910 3 0.058
Yeast
muscle structure development GO:0061061 196 0.057
Zebrafish Mouse Worm Fly
regulation of rna metabolic process GO:0051252 224 0.054
embryo development ending in birth or egg hatching GO:0009792 271 0.054
Zebrafish Worm
regulation of cell differentiation GO:0045595 142 0.052
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.052
cell motility GO:0048870 244 0.051
Fly
regulation of striated muscle cell differentiation GO:0051153 6 0.051
Mouse
regulation of cell development GO:0060284 100 0.051
Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.050
heart development GO:0007507 313 0.050
transcription dna templated GO:0006351 181 0.050
myosin filament assembly GO:0031034 6 0.050
Zebrafish Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.049
maintenance of location GO:0051235 4 0.048
embryonic organ morphogenesis GO:0048562 274 0.048
striated muscle cell development GO:0055002 108 0.047
Zebrafish Mouse Worm Fly
cation homeostasis GO:0055080 33 0.047
myotube differentiation GO:0014902 45 0.047
Zebrafish Mouse
protein complex subunit organization GO:0071822 46 0.047
Zebrafish Mouse Worm Fly
multicellular organismal reproductive process GO:0048609 35 0.046
Worm Fly
response to external stimulus GO:0009605 264 0.045
hematopoietic or lymphoid organ development GO:0048534 191 0.045
response to oxidative stress GO:0006979 11 0.044
response to external biotic stimulus GO:0043207 97 0.044
aging GO:0007568 2 0.043
axon development GO:0061564 166 0.043
Worm
cytoskeleton dependent cytokinesis GO:0061640 3 0.043
Yeast
myotube cell development GO:0014904 35 0.042
Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
cellular component movement GO:0006928 335 0.041
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.040
nucleic acid templated transcription GO:0097659 181 0.039
peptidyl serine phosphorylation GO:0018105 1 0.039
blood vessel morphogenesis GO:0048514 216 0.039
blood vessel development GO:0001568 246 0.039
regulation of circadian rhythm GO:0042752 4 0.038
small molecule metabolic process GO:0044281 77 0.038
Fly
organonitrogen compound metabolic process GO:1901564 74 0.038
Fly
embryonic organ development GO:0048568 381 0.037
tube morphogenesis GO:0035239 349 0.037
angiogenesis GO:0001525 158 0.037
extracellular matrix organization GO:0030198 27 0.036
renal system development GO:0072001 94 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.036
positive regulation of dna metabolic process GO:0051054 1 0.036
positive regulation of transport GO:0051050 2 0.035
response to stress GO:0006950 263 0.035
regulation of cellular biosynthetic process GO:0031326 245 0.034
regulation of rna biosynthetic process GO:2001141 213 0.034
single organism metabolic process GO:0044710 217 0.033
Fly
b cell activation GO:0042113 2 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
rna biosynthetic process GO:0032774 181 0.033
meiotic nuclear division GO:0007126 4 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
cytokinetic process GO:0032506 2 0.032
Yeast
negative regulation of metabolic process GO:0009892 86 0.032
multicellular organism growth GO:0035264 4 0.031
amine metabolic process GO:0009308 2 0.031
post embryonic morphogenesis GO:0009886 4 0.031
regulation of developmental process GO:0050793 247 0.031
Mouse
connective tissue development GO:0061448 99 0.031
gene expression GO:0010467 252 0.030
Fly
cellular component biogenesis GO:0044085 178 0.030
Yeast Zebrafish Mouse Worm Fly
cell substrate adhesion GO:0031589 4 0.029
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.029
skeletal system development GO:0001501 181 0.029
skeletal muscle tissue development GO:0007519 67 0.029
Zebrafish Mouse
cartilage development GO:0051216 96 0.029
response to alkaloid GO:0043279 2 0.028
oocyte anterior posterior axis specification GO:0007314 4 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.028
muscle cell development GO:0055001 115 0.028
Zebrafish Mouse Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.028
segment specification GO:0007379 12 0.028
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.028
nephron tubule morphogenesis GO:0072078 1 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
nucleotide metabolic process GO:0009117 28 0.027
Fly
homeostatic process GO:0042592 142 0.026
response to other organism GO:0051707 97 0.026
positive regulation of muscle cell differentiation GO:0051149 1 0.025
death GO:0016265 121 0.025
response to biotic stimulus GO:0009607 97 0.025
skin development GO:0043588 54 0.025
nephron epithelium morphogenesis GO:0072088 1 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
specification of symmetry GO:0009799 204 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
embryonic pattern specification GO:0009880 44 0.024
Zebrafish
extraocular skeletal muscle development GO:0002074 3 0.024
neuron projection morphogenesis GO:0048812 161 0.024
syncytium formation GO:0006949 12 0.023
synaptic transmission cholinergic GO:0007271 4 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
Fly
sequestering of calcium ion GO:0051208 3 0.023
regulation of skeletal muscle fiber development GO:0048742 2 0.023
macromolecule biosynthetic process GO:0009059 227 0.022
regulation of reproductive process GO:2000241 4 0.022
purine nucleotide metabolic process GO:0006163 27 0.022
Fly
peptidyl serine modification GO:0018209 2 0.022
myoblast fusion GO:0007520 10 0.022
outflow tract morphogenesis GO:0003151 1 0.022
cell projection morphogenesis GO:0048858 244 0.022
pharyngeal muscle development GO:0043282 4 0.022
immune system process GO:0002376 241 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
muscle attachment GO:0016203 9 0.022
determination of left right symmetry GO:0007368 179 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.021
purine nucleoside monophosphate metabolic process GO:0009126 5 0.021
Fly
regulation of biosynthetic process GO:0009889 250 0.021
regulation of calcium ion transport GO:0051924 2 0.021
rna metabolic process GO:0016070 219 0.021
regulation of cytokine mediated signaling pathway GO:0001959 3 0.020
renal tubule morphogenesis GO:0061333 1 0.020
cell fate specification GO:0001708 68 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
heterocycle metabolic process GO:0046483 290 0.020
Fly
smooth muscle tissue development GO:0048745 1 0.020
patterning of blood vessels GO:0001569 15 0.020
defense response to other organism GO:0098542 33 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
g protein coupled receptor signaling pathway GO:0007186 74 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
protein metabolic process GO:0019538 183 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.020
appendage morphogenesis GO:0035107 56 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
Fly
regulation of bmp signaling pathway GO:0030510 39 0.019
regulation of dendrite development GO:0050773 3 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of transcription dna templated GO:0006355 213 0.019
pole plasm assembly GO:0007315 4 0.019
single organism membrane fusion GO:0044801 2 0.018
protein acetylation GO:0006473 2 0.018
response to growth factor GO:0070848 39 0.018
protein complex biogenesis GO:0070271 30 0.018
Zebrafish Mouse Worm Fly
hemopoiesis GO:0030097 183 0.018
blood circulation GO:0008015 87 0.018
myosin filament organization GO:0031033 6 0.017
Zebrafish Mouse Worm Fly
extracellular matrix assembly GO:0085029 1 0.017
cellular amine metabolic process GO:0044106 2 0.017
ear development GO:0043583 127 0.017
digestive tract development GO:0048565 265 0.017
regulation of protein complex assembly GO:0043254 3 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
tissue remodeling GO:0048771 4 0.017
axonogenesis GO:0007409 152 0.017
regulation of transporter activity GO:0032409 2 0.017
regulation of signal transduction GO:0009966 225 0.017
cellular response to endogenous stimulus GO:0071495 68 0.016
negative regulation of cellular process GO:0048523 283 0.016
immune system development GO:0002520 191 0.016
cardiac chamber morphogenesis GO:0003206 12 0.016
cognition GO:0050890 1 0.016
organelle assembly GO:0070925 110 0.016
Zebrafish Mouse Worm Fly
response to nutrient GO:0007584 3 0.016
regulation of muscle cell differentiation GO:0051147 6 0.016
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
kidney development GO:0001822 92 0.016
localization of cell GO:0051674 244 0.016
Fly
negative regulation of apoptotic process GO:0043066 55 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
sarcomerogenesis GO:0048769 4 0.015
macromolecular complex assembly GO:0065003 35 0.015
Zebrafish Mouse Worm Fly
growth GO:0040007 174 0.015
negative regulation of biological process GO:0048519 304 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of cell communication GO:0010646 232 0.015
regulation of synapse organization GO:0050807 3 0.015
forebrain development GO:0030900 96 0.015
muscle cell migration GO:0014812 4 0.015
response to chemical GO:0042221 320 0.015
macromolecule catabolic process GO:0009057 15 0.015
regulation of response to stimulus GO:0048583 269 0.015
regulation of mrna processing GO:0050684 3 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
multi organism process GO:0051704 134 0.015
Worm Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
bmp signaling pathway GO:0030509 52 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
cardiac muscle myosin thick filament assembly GO:0071690 1 0.014
neurotransmitter secretion GO:0007269 2 0.014
actin filament based movement GO:0030048 1 0.014
digestive system development GO:0055123 289 0.014
wound healing GO:0042060 90 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
organic substance catabolic process GO:1901575 28 0.014
Fly
response to organic substance GO:0010033 153 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
anterior posterior pattern specification GO:0009952 152 0.014
Zebrafish
regulation of cell activation GO:0050865 1 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cellular metal ion homeostasis GO:0006875 16 0.014
axonal fasciculation GO:0007413 11 0.014
Worm
organ formation GO:0048645 17 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
Zebrafish Mouse Worm Fly
protein complex assembly GO:0006461 30 0.014
Zebrafish Mouse Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of blood pressure GO:0008217 1 0.013
positive regulation of developmental process GO:0051094 50 0.013
mesenchymal cell proliferation GO:0010463 1 0.013
negative regulation of transcription dna templated GO:0045892 45 0.013
transport GO:0006810 220 0.013
Worm
vesicle mediated transport GO:0016192 22 0.013
Worm
positive regulation of rna biosynthetic process GO:1902680 57 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
chordate embryonic development GO:0043009 271 0.013
Zebrafish
positive regulation of cell activation GO:0050867 1 0.013
adult behavior GO:0030534 2 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
mesenchyme development GO:0060485 127 0.013
chemotaxis GO:0006935 104 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
Fly
intracellular mrna localization GO:0008298 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
alcohol biosynthetic process GO:0046165 2 0.013
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.013
sequestering of metal ion GO:0051238 3 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.012
sleep GO:0030431 1 0.012
histone h3 k4 methylation GO:0051568 2 0.012
nitric oxide metabolic process GO:0046209 2 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
organism emergence from protective structure GO:0071684 4 0.012
determination of bilateral symmetry GO:0009855 204 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
protein acylation GO:0043543 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
stem cell differentiation GO:0048863 117 0.012
cytoskeleton organization GO:0007010 96 0.012
Yeast Zebrafish Mouse Worm Fly
fertilization GO:0009566 3 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
striated muscle contraction GO:0006941 12 0.012
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.012
neuron recognition GO:0008038 18 0.012
Worm
lateral line development GO:0048882 66 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
notochord development GO:0030903 54 0.012
mechanosensory behavior GO:0007638 2 0.012
protein localization to nucleus GO:0034504 3 0.012
stem cell proliferation GO:0072089 4 0.012
leukocyte proliferation GO:0070661 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cell fate commitment GO:0045165 99 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
auditory receptor cell fate commitment GO:0009912 4 0.011
cardiac muscle fiber development GO:0048739 3 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
centrosome cycle GO:0007098 1 0.011
actin cytoskeleton organization GO:0030036 63 0.011
Yeast Zebrafish Mouse Worm Fly
regulation of neurotransmitter transport GO:0051588 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
lipid metabolic process GO:0006629 52 0.011
cellular ketone metabolic process GO:0042180 11 0.011
cellular homeostasis GO:0019725 26 0.011
lymphoid lineage cell migration into thymus GO:0097535 4 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
aromatic compound catabolic process GO:0019439 15 0.011
Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
positive regulation of biological process GO:0048518 253 0.011
defense response GO:0006952 47 0.011
neuronal action potential GO:0019228 18 0.011
mesoderm development GO:0007498 88 0.011
myeloid cell homeostasis GO:0002262 56 0.011
circadian sleep wake cycle GO:0042745 2 0.011
camera type eye development GO:0043010 222 0.011
regulation of cell projection assembly GO:0060491 4 0.011
peptidyl lysine methylation GO:0018022 3 0.011
endocytosis GO:0006897 16 0.011
Worm
membrane fusion GO:0061025 2 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
actomyosin structure organization GO:0031032 53 0.011
Yeast Zebrafish Mouse Worm Fly
regulation of cell fate specification GO:0042659 20 0.011
negative regulation of gene expression GO:0010629 65 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
multicellular organism reproduction GO:0032504 35 0.011
Worm Fly
meiotic cell cycle process GO:1903046 3 0.011
chemical homeostasis GO:0048878 49 0.011
convergent extension GO:0060026 118 0.010
inner ear development GO:0048839 126 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
sensory system development GO:0048880 76 0.010
muscle tissue morphogenesis GO:0060415 7 0.010
regulation of gene expression epigenetic GO:0040029 11 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
cellular response to growth factor stimulus GO:0071363 39 0.010
regulation of localization GO:0032879 104 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
Fly
positive regulation of cell division GO:0051781 2 0.010

myhc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
sensory system disease DOID:0050155 0 0.047
eye and adnexa disease DOID:1492 0 0.030
eye disease DOID:5614 0 0.030
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.015
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.011
mitochondrial metabolism disease DOID:700 0 0.011
musculoskeletal system disease DOID:17 0 0.011