Danio rerio

54 known processes

mylk3

myosin light chain kinase 3

(Aliases: fc41h03,mlck,wu:fc41h03,bZ34G2.1,si:rp71-34g2.1)

mylk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.500
heart morphogenesis GO:0003007 156 0.461
determination of left right symmetry GO:0007368 179 0.397
determination of bilateral symmetry GO:0009855 204 0.301
embryonic heart tube morphogenesis GO:0003143 108 0.287
embryonic heart tube development GO:0035050 133 0.280
specification of symmetry GO:0009799 204 0.237
embryonic organ morphogenesis GO:0048562 274 0.227
determination of heart left right asymmetry GO:0061371 117 0.214
muscle structure development GO:0061061 196 0.205
muscle cell differentiation GO:0042692 139 0.179
regulation of multicellular organismal process GO:0051239 277 0.178
cardiac muscle tissue development GO:0048738 48 0.168
heart contraction GO:0060047 71 0.154
tube morphogenesis GO:0035239 349 0.151
embryonic organ development GO:0048568 381 0.144
heart looping GO:0001947 94 0.141
striated muscle cell development GO:0055002 108 0.139
muscle tissue development GO:0060537 110 0.133
cardiac muscle cell differentiation GO:0055007 30 0.127
cardiac cell development GO:0055006 21 0.119
striated muscle tissue development GO:0014706 110 0.116
morphogenesis of an epithelium GO:0002009 333 0.113
ventricular cardiac muscle tissue development GO:0003229 3 0.106
larval development GO:0002164 2 0.102
system process GO:0003008 185 0.101
regulation of muscle contraction GO:0006937 3 0.100
heart process GO:0003015 71 0.073
positive regulation of blood circulation GO:1903524 2 0.071
cellular component assembly GO:0022607 170 0.069
blood circulation GO:0008015 87 0.069
cardiac muscle cell development GO:0055013 20 0.065
eye morphogenesis GO:0048592 144 0.064
cellular component biogenesis GO:0044085 178 0.064
circulatory system process GO:0003013 87 0.063
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.062
maintenance of location GO:0051235 4 0.059
single organism organelle organization GO:1902589 199 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.052
organelle assembly GO:0070925 110 0.052
blood vessel development GO:0001568 246 0.052
cardiac conduction GO:0061337 3 0.051
eye development GO:0001654 277 0.051
skeletal muscle organ development GO:0060538 78 0.051
muscle cell development GO:0055001 115 0.049
positive regulation of catabolic process GO:0009896 4 0.048
cellular component morphogenesis GO:0032989 336 0.047
epithelial tube morphogenesis GO:0060562 148 0.047
cellular component assembly involved in morphogenesis GO:0010927 107 0.047
locomotion GO:0040011 313 0.043
regulation of response to stimulus GO:0048583 269 0.041
regulation of heart contraction GO:0008016 32 0.040
striated muscle cell differentiation GO:0051146 129 0.040
response to external stimulus GO:0009605 264 0.039
aging GO:0007568 2 0.039
tissue remodeling GO:0048771 4 0.039
neuron differentiation GO:0030182 353 0.038
heterocycle metabolic process GO:0046483 290 0.038
brain development GO:0007420 293 0.037
cardiocyte differentiation GO:0035051 44 0.037
cell surface receptor signaling pathway GO:0007166 325 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.036
positive regulation of transport GO:0051050 2 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
regulation of blood circulation GO:1903522 32 0.035
cation transport GO:0006812 81 0.035
positive regulation of heart contraction GO:0045823 2 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
calcium ion transport into cytosol GO:0060402 3 0.034
regulation of cellular metabolic process GO:0031323 320 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
response to topologically incorrect protein GO:0035966 2 0.032
regulation of stem cell proliferation GO:0072091 2 0.032
protein import GO:0017038 3 0.032
transport GO:0006810 220 0.030
sodium ion transmembrane transport GO:0035725 21 0.030
regulation of sequestering of calcium ion GO:0051282 4 0.030
sensory organ development GO:0007423 393 0.030
cation transmembrane transport GO:0098655 65 0.029
vasculature development GO:0001944 278 0.029
sensory organ morphogenesis GO:0090596 200 0.029
actin filament based movement GO:0030048 1 0.029
single organism localization GO:1902578 225 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
organic substance biosynthetic process GO:1901576 289 0.029
transmembrane transport GO:0055085 120 0.028
neuron development GO:0048666 262 0.028
muscle organ development GO:0007517 101 0.028
positive regulation of biological process GO:0048518 253 0.028
gene expression GO:0010467 252 0.028
striated muscle contraction GO:0006941 12 0.028
stem cell maintenance GO:0019827 4 0.028
chemosensory behavior GO:0007635 1 0.027
digestive tract development GO:0048565 265 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
positive regulation of epithelial cell proliferation GO:0050679 1 0.027
meiotic nuclear division GO:0007126 4 0.027
single organism transport GO:0044765 206 0.027
sequestering of metal ion GO:0051238 3 0.027
gtp catabolic process GO:0006184 2 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
branching morphogenesis of a nerve GO:0048755 4 0.026
organelle organization GO:0006996 227 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
cardiac myofibril assembly GO:0055003 9 0.026
regulation of metal ion transport GO:0010959 4 0.025
signal transduction GO:0007165 455 0.025
regulation of protein complex assembly GO:0043254 3 0.025
sequestering of calcium ion GO:0051208 3 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of signal transduction GO:0009966 225 0.023
cell projection organization GO:0030030 284 0.023
regulation of metabolic process GO:0019222 359 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
central nervous system development GO:0007417 387 0.023
membrane repolarization GO:0086009 2 0.023
cytosolic calcium ion transport GO:0060401 3 0.023
gastrulation GO:0007369 208 0.023
actin filament based process GO:0030029 64 0.023
regulation of cell communication GO:0010646 232 0.023
calcium ion import GO:0070509 4 0.023
cytokinesis GO:0000910 3 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
head development GO:0060322 303 0.022
leukocyte proliferation GO:0070661 1 0.022
regulation of biological quality GO:0065008 263 0.022
regulation of synapse assembly GO:0051963 3 0.022
cellular component movement GO:0006928 335 0.022
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
single organism metabolic process GO:0044710 217 0.022
establishment of localization GO:0051234 244 0.022
positive regulation of cellular process GO:0048522 201 0.021
negative regulation of gliogenesis GO:0014014 1 0.021
response to unfolded protein GO:0006986 2 0.021
regulation of system process GO:0044057 40 0.021
mesenchymal cell differentiation GO:0048762 87 0.021
positive regulation of nucleotide catabolic process GO:0030813 1 0.021
protein import into nucleus GO:0006606 3 0.021
response to stress GO:0006950 263 0.021
cellular localization GO:0051641 97 0.020
cytoskeleton organization GO:0007010 96 0.020
chordate embryonic development GO:0043009 271 0.020
rna localization GO:0006403 4 0.020
spermatid differentiation GO:0048515 2 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
neurotransmitter transport GO:0006836 2 0.020
angiogenesis GO:0001525 158 0.020
localization of cell GO:0051674 244 0.020
regulation of membrane repolarization GO:0060306 1 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
skeletal system development GO:0001501 181 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
cell part morphogenesis GO:0032990 246 0.019
neurological system process GO:0050877 62 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
atrial cardiac myofibril assembly GO:0055004 2 0.019
locomotor rhythm GO:0045475 3 0.019
ovulation cycle process GO:0022602 2 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
digestive tract morphogenesis GO:0048546 231 0.019
photoreceptor cell fate commitment GO:0046552 1 0.019
cell morphogenesis GO:0000902 289 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
positive regulation of cell cycle GO:0045787 3 0.018
sarcomere organization GO:0045214 26 0.018
cell projection morphogenesis GO:0048858 244 0.018
regulation of signaling GO:0023051 235 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
negative regulation of biological process GO:0048519 304 0.018
sleep GO:0030431 1 0.018
positive regulation of cytokine production GO:0001819 2 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
cellular protein catabolic process GO:0044257 4 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
ion transport GO:0006811 114 0.018
nuclear import GO:0051170 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
inner ear morphogenesis GO:0042472 63 0.017
regulation of circadian rhythm GO:0042752 4 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
phagocytosis GO:0006909 3 0.017
regulation of protein transport GO:0051223 3 0.017
myofibril assembly GO:0030239 48 0.017
neuron projection development GO:0031175 180 0.017
negative regulation of signaling GO:0023057 96 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
retina development in camera type eye GO:0060041 146 0.017
convergent extension involved in gastrulation GO:0060027 71 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
skeletal muscle tissue development GO:0007519 67 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
regulation of transcription dna templated GO:0006355 213 0.016
er nucleus signaling pathway GO:0006984 2 0.016
neurotransmitter secretion GO:0007269 2 0.016
wnt signaling pathway GO:0016055 80 0.016
actin cytoskeleton organization GO:0030036 63 0.016
lipid storage GO:0019915 1 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cellular response to topologically incorrect protein GO:0035967 2 0.016
lens fiber cell morphogenesis GO:0070309 3 0.016
amine metabolic process GO:0009308 2 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
rna metabolic process GO:0016070 219 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of localization GO:0032879 104 0.016
multi organism reproductive process GO:0044703 36 0.016
biosynthetic process GO:0009058 294 0.016
cellular response to unfolded protein GO:0034620 2 0.016
notochord development GO:0030903 54 0.015
protein dephosphorylation GO:0006470 3 0.015
startle response GO:0001964 4 0.015
negative regulation of signal transduction GO:0009968 94 0.015
regulation of neurogenesis GO:0050767 87 0.015
protein secretion GO:0009306 1 0.015
oxoacid metabolic process GO:0043436 31 0.015
negative regulation of cellular process GO:0048523 283 0.015
positive regulation of secretion GO:0051047 1 0.015
nucleic acid transport GO:0050657 2 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
regulation of gene expression GO:0010468 265 0.015
organic acid metabolic process GO:0006082 31 0.015
smooth muscle contraction GO:0006939 2 0.015
outflow tract morphogenesis GO:0003151 1 0.014
epithelial cell differentiation GO:0030855 116 0.014
regulation of calcium ion transport GO:0051924 2 0.014
inner ear development GO:0048839 126 0.014
stem cell proliferation GO:0072089 4 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
regulation of reproductive process GO:2000241 4 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
rna transport GO:0050658 2 0.014
gtp metabolic process GO:0046039 4 0.014
neuron projection morphogenesis GO:0048812 161 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
multi organism process GO:0051704 134 0.014
cellular biosynthetic process GO:0044249 286 0.014
somatic muscle development GO:0007525 4 0.014
axon development GO:0061564 166 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
female gonad development GO:0008585 4 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
digestive system development GO:0055123 289 0.014
camera type eye development GO:0043010 222 0.014
protein modification process GO:0036211 100 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
cranial nerve development GO:0021545 42 0.013
establishment of rna localization GO:0051236 3 0.013
detection of mechanical stimulus GO:0050982 11 0.013
fin development GO:0033333 77 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
developmental programmed cell death GO:0010623 4 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
axon guidance GO:0007411 86 0.013
compound eye development GO:0048749 2 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
response to abiotic stimulus GO:0009628 122 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
metal ion transport GO:0030001 58 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
regulation of tube size GO:0035150 2 0.013
nucleic acid templated transcription GO:0097659 181 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of binding GO:0051098 3 0.013
blood vessel morphogenesis GO:0048514 216 0.013
cellular amine metabolic process GO:0044106 2 0.013
regulation of developmental process GO:0050793 247 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
cardiac atrium morphogenesis GO:0003209 2 0.012
ion transmembrane transport GO:0034220 91 0.012
photoreceptor cell fate specification GO:0043704 1 0.012
female sex differentiation GO:0046660 4 0.012
developmental growth GO:0048589 166 0.012
lymphocyte proliferation GO:0046651 1 0.012
establishment of localization in cell GO:0051649 77 0.012
adult behavior GO:0030534 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
regulation of protein catabolic process GO:0042176 1 0.012
heart valve formation GO:0003188 4 0.012
regulation of organelle assembly GO:1902115 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
regulation of cytokine production GO:0001817 3 0.012
cell fate specification GO:0001708 68 0.012
protein homooligomerization GO:0051260 3 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
regulation of neurological system process GO:0031644 2 0.012
regulation of cell activation GO:0050865 1 0.012
response to chemical GO:0042221 320 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
protein metabolic process GO:0019538 183 0.012
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.012
negative regulation of defense response GO:0031348 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of blood pressure GO:0008217 1 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
regulation of jak stat cascade GO:0046425 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
fin morphogenesis GO:0033334 53 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of transporter activity GO:0032409 2 0.012
transcription dna templated GO:0006351 181 0.012
single organism nuclear import GO:1902593 3 0.011
negative regulation of neurogenesis GO:0050768 20 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
mitochondrion organization GO:0007005 4 0.011
cilium morphogenesis GO:0060271 85 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.011
mitochondrial transport GO:0006839 2 0.011
embryonic skeletal joint development GO:0072498 3 0.011
ion homeostasis GO:0050801 41 0.011
meiotic cell cycle process GO:1903046 3 0.011
somitogenesis GO:0001756 87 0.011
hormone secretion GO:0046879 2 0.011
connective tissue development GO:0061448 99 0.011
cardiac atrium development GO:0003230 4 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of epidermis development GO:0045682 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
spermatid development GO:0007286 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cellular response to external stimulus GO:0071496 2 0.011
cellular response to nutrient levels GO:0031669 2 0.011
cell substrate adhesion GO:0031589 4 0.011
cell matrix adhesion GO:0007160 4 0.011
regulation of biosynthetic process GO:0009889 250 0.011
cellular response to starvation GO:0009267 1 0.011
somite development GO:0061053 96 0.011
glial cell migration GO:0008347 3 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
muscle fiber development GO:0048747 52 0.011
regulation of blood vessel size GO:0050880 2 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
pericardium development GO:0060039 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
protein targeting to nucleus GO:0044744 3 0.011
endocrine system development GO:0035270 65 0.010
convergent extension GO:0060026 118 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
regulation of wound healing GO:0061041 2 0.010
response to carbohydrate GO:0009743 3 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
post embryonic organ development GO:0048569 4 0.010
cardiac conduction system development GO:0003161 1 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
nerve development GO:0021675 45 0.010
axonogenesis GO:0007409 152 0.010
regionalization GO:0003002 274 0.010
atrial cardiac muscle cell development GO:0055014 4 0.010
nuclear transport GO:0051169 4 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
gland development GO:0048732 143 0.010

mylk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.096
disease of anatomical entity DOID:7 0 0.096
muscle tissue disease DOID:66 0 0.069
musculoskeletal system disease DOID:17 0 0.069
intrinsic cardiomyopathy DOID:0060036 0 0.069
cardiomyopathy DOID:0050700 0 0.069
myopathy DOID:423 0 0.069
heart disease DOID:114 0 0.069
muscular disease DOID:0080000 0 0.069
hypertrophic cardiomyopathy DOID:11984 0 0.069
immune system disease DOID:2914 0 0.019
nervous system disease DOID:863 0 0.017
hematopoietic system disease DOID:74 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011