Danio rerio

0 known processes

mylz2

myosin, light polypeptide 2, skeletal muscle

(Aliases: sb:cb46,cb46,mlc2f)

mylz2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 64 0.970
Zebrafish
muscle system process GO:0003012 20 0.948
Worm
myofibril assembly GO:0030239 48 0.924
Zebrafish
skeletal muscle thin filament assembly GO:0030240 4 0.915
ventricular cardiac myofibril assembly GO:0055005 4 0.905
Zebrafish
muscle cell development GO:0055001 115 0.894
Zebrafish
skeletal myofibril assembly GO:0014866 7 0.875
embryo development ending in birth or egg hatching GO:0009792 271 0.871
single organism organelle organization GO:1902589 199 0.863
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.852
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.852
Zebrafish
muscle contraction GO:0006936 18 0.811
Worm
myotube differentiation GO:0014902 45 0.788
cellular component assembly GO:0022607 170 0.770
Zebrafish
cytokinesis GO:0000910 3 0.769
cellular component biogenesis GO:0044085 178 0.711
Zebrafish
system process GO:0003008 185 0.697
Zebrafish Worm
purine nucleoside monophosphate catabolic process GO:0009128 4 0.684
muscle cell differentiation GO:0042692 139 0.652
Zebrafish
cellular component morphogenesis GO:0032989 336 0.635
Zebrafish
cellular amino acid biosynthetic process GO:0008652 2 0.623
organelle organization GO:0006996 227 0.600
Zebrafish
biosynthetic process GO:0009058 294 0.583
skeletal muscle contraction GO:0003009 5 0.582
nitrogen compound metabolic process GO:0006807 319 0.581
actomyosin structure organization GO:0031032 53 0.568
Zebrafish
organelle assembly GO:0070925 110 0.551
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.537
generation of neurons GO:0048699 385 0.465
muscle tissue development GO:0060537 110 0.465
Zebrafish Mouse Rat
voluntary skeletal muscle contraction GO:0003010 4 0.464
embryonic heart tube development GO:0035050 133 0.459
musculoskeletal movement GO:0050881 8 0.415
muscle structure development GO:0061061 196 0.408
Zebrafish Mouse Rat Worm
skeletal muscle organ development GO:0060538 78 0.405
Mouse Rat
striated muscle contraction GO:0006941 12 0.399
striated muscle cell development GO:0055002 108 0.396
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.395
atp catabolic process GO:0006200 4 0.371
myosin filament organization GO:0031033 6 0.364
twitch skeletal muscle contraction GO:0014721 4 0.342
ventricular cardiac muscle cell differentiation GO:0055012 6 0.336
Zebrafish
heart development GO:0007507 313 0.328
Zebrafish
multi organism process GO:0051704 134 0.324
Worm
locomotion GO:0040011 313 0.323
Worm
sarcomere organization GO:0045214 26 0.322
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.317
larval development GO:0002164 2 0.312
Worm
neuron development GO:0048666 262 0.308
nucleoside monophosphate catabolic process GO:0009125 4 0.304
striated muscle tissue development GO:0014706 110 0.301
Zebrafish Mouse Rat
actin cytoskeleton organization GO:0030036 63 0.298
Zebrafish
actin filament based movement GO:0030048 1 0.294
heterocycle biosynthetic process GO:0018130 215 0.289
skeletal muscle tissue development GO:0007519 67 0.285
Mouse Rat
macromolecular complex subunit organization GO:0043933 74 0.258
cytoskeleton dependent cytokinesis GO:0061640 3 0.256
sequestering of calcium ion GO:0051208 3 0.230
chordate embryonic development GO:0043009 271 0.225
multicellular organismal movement GO:0050879 8 0.223
behavior GO:0007610 74 0.222
Worm
cardiac myofibril assembly GO:0055003 9 0.222
Zebrafish
positive regulation of biological process GO:0048518 253 0.221
Zebrafish
neuron differentiation GO:0030182 353 0.217
regulation of macromolecule biosynthetic process GO:0010556 225 0.216
reproduction GO:0000003 40 0.207
Worm
signal transduction GO:0007165 455 0.200
regulation of metabolic process GO:0019222 359 0.193
anatomical structure homeostasis GO:0060249 36 0.190
myotube cell development GO:0014904 35 0.184
cellular aromatic compound metabolic process GO:0006725 295 0.167
organonitrogen compound metabolic process GO:1901564 74 0.166
regulation of sarcomere organization GO:0060297 2 0.163
organic substance biosynthetic process GO:1901576 289 0.163
regulation of cellular metabolic process GO:0031323 320 0.162
regulation of muscle contraction GO:0006937 3 0.158
Worm
lymphoid lineage cell migration GO:0097534 4 0.157
heart process GO:0003015 71 0.155
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.152
somite development GO:0061053 96 0.151
regulation of primary metabolic process GO:0080090 311 0.149
gene expression GO:0010467 252 0.148
cell division GO:0051301 20 0.146
cell part morphogenesis GO:0032990 246 0.145
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.140
response to stress GO:0006950 263 0.138
somitogenesis GO:0001756 87 0.132
reactive nitrogen species metabolic process GO:2001057 0 0.130
cellular component assembly involved in morphogenesis GO:0010927 107 0.130
Zebrafish
cell projection organization GO:0030030 284 0.130
cell motility GO:0048870 244 0.123
establishment of localization GO:0051234 244 0.122
cellular nitrogen compound metabolic process GO:0034641 290 0.117
axon development GO:0061564 166 0.115
cytoskeleton organization GO:0007010 96 0.112
Zebrafish
cellular protein complex assembly GO:0043623 19 0.111
calcium ion homeostasis GO:0055074 19 0.109
cell projection morphogenesis GO:0048858 244 0.108
neuron projection development GO:0031175 180 0.107
somite specification GO:0001757 12 0.106
lymphoid lineage cell migration into thymus GO:0097535 4 0.106
heterocycle metabolic process GO:0046483 290 0.104
multicellular organismal reproductive process GO:0048609 35 0.103
Worm
anterior posterior pattern specification GO:0009952 152 0.103
blood circulation GO:0008015 87 0.103
Zebrafish
multi organism reproductive process GO:0044703 36 0.101
Worm
regulation of transcription dna templated GO:0006355 213 0.099
growth plate cartilage morphogenesis GO:0003422 1 0.098
adult behavior GO:0030534 2 0.094
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.093
regulation of macromolecule metabolic process GO:0060255 317 0.093
muscle fiber development GO:0048747 52 0.093
cation homeostasis GO:0055080 33 0.092
myosin filament assembly GO:0031034 6 0.091
cell migration GO:0016477 237 0.091
heart morphogenesis GO:0003007 156 0.091
cell morphogenesis GO:0000902 289 0.089
positive regulation of nucleoside metabolic process GO:0045979 1 0.089
protein complex subunit organization GO:0071822 46 0.088
nucleic acid metabolic process GO:0090304 244 0.085
skeletal muscle fiber development GO:0048741 35 0.083
regulation of nitrogen compound metabolic process GO:0051171 251 0.082
cardiac cell development GO:0055006 21 0.082
Zebrafish
mitotic cell cycle GO:0000278 64 0.081
cellular component movement GO:0006928 335 0.080
nucleic acid templated transcription GO:0097659 181 0.080
regulation of purine nucleotide catabolic process GO:0033121 2 0.078
single organism metabolic process GO:0044710 217 0.078
cardiac muscle fiber development GO:0048739 3 0.077
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.077
somatic muscle development GO:0007525 4 0.076
endocardial cushion formation GO:0003272 2 0.076
neuron projection morphogenesis GO:0048812 161 0.075
membrane repolarization GO:0086009 2 0.074
taxis GO:0042330 109 0.073
aging GO:0007568 2 0.073
protein complex assembly GO:0006461 30 0.073
cardiocyte differentiation GO:0035051 44 0.072
Zebrafish
regulation of response to stimulus GO:0048583 269 0.071
Worm
regulation of cellular component organization GO:0051128 86 0.067
regulation of metal ion transport GO:0010959 4 0.065
axonogenesis GO:0007409 152 0.064
positive regulation of cellular metabolic process GO:0031325 94 0.063
regulation of cell communication GO:0010646 232 0.063
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.062
ribonucleotide metabolic process GO:0009259 27 0.062
muscle organ development GO:0007517 101 0.061
Mouse Rat Worm
purine nucleotide metabolic process GO:0006163 27 0.060
response to organic substance GO:0010033 153 0.060
positive regulation of transcription dna templated GO:0045893 57 0.060
small molecule metabolic process GO:0044281 77 0.060
response to other organism GO:0051707 97 0.060
mitotic cell cycle process GO:1903047 48 0.058
embryonic organ development GO:0048568 381 0.054
rna biosynthetic process GO:0032774 181 0.054
purine containing compound metabolic process GO:0072521 29 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.050
regulation of skeletal muscle fiber development GO:0048742 2 0.050
positive regulation of metabolic process GO:0009893 108 0.050
regulation of heart growth GO:0060420 2 0.050
regionalization GO:0003002 274 0.050
post embryonic organ development GO:0048569 4 0.049
regulation of rna biosynthetic process GO:2001141 213 0.049
cell cycle process GO:0022402 53 0.048
heart looping GO:0001947 94 0.048
maintenance of location GO:0051235 4 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.047
carbohydrate derivative metabolic process GO:1901135 61 0.046
single organism biosynthetic process GO:0044711 71 0.046
regulation of developmental process GO:0050793 247 0.045
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
cellular biosynthetic process GO:0044249 286 0.044
regulation of anatomical structure morphogenesis GO:0022603 130 0.044
oxoacid metabolic process GO:0043436 31 0.043
cellular macromolecule metabolic process GO:0044260 391 0.043
regulation of nitric oxide mediated signal transduction GO:0010749 1 0.042
lipid storage GO:0019915 1 0.041
negative regulation of cellular process GO:0048523 283 0.041
atp metabolic process GO:0046034 5 0.040
cardiac muscle contraction GO:0060048 6 0.039
cardiac muscle tissue development GO:0048738 48 0.039
Zebrafish
reactive oxygen species metabolic process GO:0072593 6 0.039
cellular macromolecule biosynthetic process GO:0034645 224 0.039
phosphate containing compound metabolic process GO:0006796 108 0.039
heterocycle catabolic process GO:0046700 15 0.038
oogenesis GO:0048477 14 0.038
aromatic compound biosynthetic process GO:0019438 217 0.038
ventricular cardiac muscle tissue development GO:0003229 3 0.038
response to external stimulus GO:0009605 264 0.037
striated muscle myosin thick filament assembly GO:0071688 6 0.037
ribose phosphate metabolic process GO:0019693 27 0.037
macromolecular complex assembly GO:0065003 35 0.037
mitochondrion organization GO:0007005 4 0.037
purine ribonucleotide metabolic process GO:0009150 27 0.036
connective tissue development GO:0061448 99 0.036
protein complex disassembly GO:0043241 1 0.036
organic acid metabolic process GO:0006082 31 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
Zebrafish Worm
digestive system development GO:0055123 289 0.035
reactive oxygen species biosynthetic process GO:1903409 1 0.035
blood vessel development GO:0001568 246 0.035
cell cycle GO:0007049 93 0.035
embryonic heart tube morphogenesis GO:0003143 108 0.035
regulation of protein complex assembly GO:0043254 3 0.035
cellular modified amino acid metabolic process GO:0006575 3 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.033
transport GO:0006810 220 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.033
regulation of catalytic activity GO:0050790 55 0.032
rna metabolic process GO:0016070 219 0.032
cellular macromolecular complex assembly GO:0034622 24 0.031
oocyte anterior posterior axis specification GO:0007314 4 0.031
muscle organ morphogenesis GO:0048644 8 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
adherens junction organization GO:0034332 4 0.031
actin filament organization GO:0007015 15 0.031
cardiac muscle cell development GO:0055013 20 0.029
Zebrafish
tube morphogenesis GO:0035239 349 0.029
response to drug GO:0042493 3 0.029
regulation of protein polymerization GO:0032271 2 0.029
phosphorus metabolic process GO:0006793 109 0.029
regulation of signal transduction GO:0009966 225 0.029
positive regulation of rna biosynthetic process GO:1902680 57 0.028
cell matrix adhesion GO:0007160 4 0.028
positive regulation of cellular process GO:0048522 201 0.028
regulation of rna metabolic process GO:0051252 224 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
catabolic process GO:0009056 32 0.027
regulation of anatomical structure size GO:0090066 33 0.026
body morphogenesis GO:0010171 16 0.026
protein metabolic process GO:0019538 183 0.026
intracellular signal transduction GO:0035556 85 0.025
germ cell development GO:0007281 22 0.025
digestive tract development GO:0048565 265 0.025
regulation of ion transmembrane transporter activity GO:0032412 2 0.025
multicellular organism reproduction GO:0032504 35 0.025
Worm
defense response GO:0006952 47 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of cytoskeleton organization GO:0051493 11 0.025
purine nucleoside monophosphate metabolic process GO:0009126 5 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
transcription dna templated GO:0006351 181 0.025
mitotic cytokinesis GO:0000281 3 0.025
regulation of actin filament based process GO:0032970 9 0.024
positive regulation of macromolecule metabolic process GO:0010604 93 0.024
muscle tissue morphogenesis GO:0060415 7 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
organophosphate metabolic process GO:0019637 37 0.024
pole plasm assembly GO:0007315 4 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
angiogenesis GO:0001525 158 0.023
regulation of actin cytoskeleton organization GO:0032956 8 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
positive regulation of gene expression GO:0010628 71 0.022
heart contraction GO:0060047 71 0.022
Zebrafish
regulation of myotube differentiation GO:0010830 2 0.022
protein polymerization GO:0051258 4 0.022
macromolecule catabolic process GO:0009057 15 0.022
single organism localization GO:1902578 225 0.022
skeletal muscle myosin thick filament assembly GO:0030241 5 0.021
protein complex biogenesis GO:0070271 30 0.021
reproductive process GO:0022414 40 0.021
Worm
regulation of striated muscle contraction GO:0006942 2 0.021
nucleoside phosphate metabolic process GO:0006753 28 0.021
regulation of transporter activity GO:0032409 2 0.021
localization of cell GO:0051674 244 0.021
rna localization GO:0006403 4 0.021
response to nutrient GO:0007584 3 0.020
regulation of transmembrane transport GO:0034762 18 0.020
regulation of reproductive process GO:2000241 4 0.020
defense response to other organism GO:0098542 33 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
er nucleus signaling pathway GO:0006984 2 0.020
regulation of gene expression GO:0010468 265 0.020
axonal fasciculation GO:0007413 11 0.019
renal system development GO:0072001 94 0.019
protein stabilization GO:0050821 2 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
endocardial cushion morphogenesis GO:0003203 3 0.019
actin filament polymerization GO:0030041 2 0.018
tissue remodeling GO:0048771 4 0.018
protein acylation GO:0043543 3 0.018
cardiac muscle tissue morphogenesis GO:0055008 7 0.018
regulation of biological quality GO:0065008 263 0.018
response to external biotic stimulus GO:0043207 97 0.018
negative regulation of biological process GO:0048519 304 0.018
cellular localization GO:0051641 97 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
divalent inorganic cation homeostasis GO:0072507 22 0.017
regulation of sequestering of calcium ion GO:0051282 4 0.017
protein import into nucleus GO:0006606 3 0.017
response to wounding GO:0009611 116 0.017
nitric oxide biosynthetic process GO:0006809 2 0.017
segmentation GO:0035282 97 0.017
regulation of protein complex disassembly GO:0043244 1 0.017
post embryonic morphogenesis GO:0009886 4 0.017
response to chemical GO:0042221 320 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
amine metabolic process GO:0009308 2 0.017
ribonucleoside triphosphate metabolic process GO:0009199 9 0.016
programmed cell death GO:0012501 119 0.016
protein localization to nucleus GO:0034504 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of signaling GO:0023051 235 0.016
organonitrogen compound biosynthetic process GO:1901566 47 0.016
nitric oxide metabolic process GO:0046209 2 0.016
regulation of cytokine mediated signaling pathway GO:0001959 3 0.015
gastrulation GO:0007369 208 0.015
cell substrate adhesion GO:0031589 4 0.015
organic substance catabolic process GO:1901575 28 0.015
regulation of calcium ion transport GO:0051924 2 0.015
positive regulation of catabolic process GO:0009896 4 0.015
aromatic compound catabolic process GO:0019439 15 0.015
negative regulation of kinase activity GO:0033673 4 0.015
regulation of organelle organization GO:0033043 29 0.015
glycosyl compound metabolic process GO:1901657 11 0.015
regulation of cell development GO:0060284 100 0.015
calcium ion import GO:0070509 4 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
nucleoside metabolic process GO:0009116 11 0.014
regulation of blood pressure GO:0008217 1 0.014
directional locomotion GO:0033058 1 0.014
oocyte development GO:0048599 14 0.014
regulation of circadian rhythm GO:0042752 4 0.014
chemotaxis GO:0006935 104 0.014
p38mapk cascade GO:0038066 1 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
positive regulation of transport GO:0051050 2 0.014
nucleotide metabolic process GO:0009117 28 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
positive regulation of striated muscle cell differentiation GO:0051155 1 0.013
regulation of membrane potential GO:0042391 23 0.013
nucleoside biosynthetic process GO:0009163 2 0.013
intestinal epithelial cell differentiation GO:0060575 3 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of cellular component size GO:0032535 30 0.013
regulation of cell shape GO:0008360 1 0.013
cellular response to organic substance GO:0071310 105 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
regulation of mrna processing GO:0050684 3 0.012
venous blood vessel morphogenesis GO:0048845 3 0.012
small molecule catabolic process GO:0044282 3 0.012
eye development GO:0001654 277 0.012
cellular divalent inorganic cation homeostasis GO:0072503 13 0.012
regulation of protein binding GO:0043393 3 0.012
female gamete generation GO:0007292 14 0.012
response to activity GO:0014823 14 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
vasculature development GO:0001944 278 0.012
myoblast fusion GO:0007520 10 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
positive regulation of muscle cell differentiation GO:0051149 1 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
stem cell differentiation GO:0048863 117 0.011
protein depolymerization GO:0051261 1 0.011
pharyngeal muscle development GO:0043282 4 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.011
post embryonic development GO:0009791 7 0.011
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.011
positive regulation of hydrolase activity GO:0051345 13 0.011
cellular amine metabolic process GO:0044106 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
vesicle mediated transport GO:0016192 22 0.011
nucleoside triphosphate biosynthetic process GO:0009142 2 0.011
skeletal system development GO:0001501 181 0.010
homeostatic process GO:0042592 142 0.010
nuclear division GO:0000280 23 0.010
regulation of locomotion GO:0040012 55 0.010
cellular metal ion homeostasis GO:0006875 16 0.010

mylz2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.282
musculoskeletal system disease DOID:17 0 0.121
myopathy DOID:423 0 0.025
muscular disease DOID:0080000 0 0.025
heart disease DOID:114 0 0.025
cardiomyopathy DOID:0050700 0 0.025
intrinsic cardiomyopathy DOID:0060036 0 0.025
cardiovascular system disease DOID:1287 0 0.025
muscle tissue disease DOID:66 0 0.025
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.019
osteochondrodysplasia DOID:2256 0 0.018
osteogenesis imperfecta DOID:12347 0 0.018
bone development disease DOID:0080006 0 0.018
bone disease DOID:0080001 0 0.018
connective tissue disease DOID:65 0 0.018
distal arthrogryposis DOID:0050646 0 0.014
gastrointestinal system cancer DOID:3119 0 0.013