|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.385
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.350
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.339
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.298
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.279
|
Human |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.265
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.260
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.255
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.249
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.240
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.209
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.208
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.205
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.203
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.199
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.199
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.195
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.189
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.184
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.182
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.176
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.175
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.175
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.173
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.172
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.168
|
|
|
|
aging
|
GO:0007568 |
2 |
0.162
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.160
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.159
|
Human |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.157
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.154
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.151
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.143
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.141
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.137
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.136
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.131
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.131
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.130
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.129
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.128
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.125
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.117
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.116
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.115
|
Human Fly |
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.114
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.114
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.113
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.113
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.111
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.107
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.107
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.105
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.102
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.099
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.099
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.096
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.096
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.095
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.094
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.094
|
|
|
|
death
|
GO:0016265 |
121 |
0.094
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.094
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.093
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.092
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.090
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.089
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.089
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.086
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.084
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
3 |
0.084
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.084
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.082
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.082
|
|
|
|
protein stabilization
|
GO:0050821 |
2 |
0.078
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.077
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.077
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.076
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.076
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.074
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.073
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.073
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.073
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.072
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.068
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.068
|
|
|
|
system process
|
GO:0003008 |
185 |
0.067
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.067
|
Human Fly |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.066
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.065
|
Human |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.065
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.065
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.064
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.064
|
|
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.063
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.063
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.063
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.062
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.062
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.059
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.058
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.057
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.056
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
0 |
0.056
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
2 |
0.056
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.055
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.055
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.055
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.054
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
1 |
0.054
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.054
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.053
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.053
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.053
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.052
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.052
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.052
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.051
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.051
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.051
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
4 |
0.051
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.050
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.050
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.050
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
1 |
0.049
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.049
|
Fly |
|
|
response to stress
|
GO:0006950 |
263 |
0.049
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.048
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.048
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.048
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.047
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
4 |
0.046
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.045
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.044
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.044
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.044
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.043
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.043
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.043
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.042
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.042
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.041
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.041
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.041
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.041
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.041
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.040
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.040
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.039
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.039
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.039
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.039
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.039
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.038
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.038
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
1 |
0.038
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.038
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.038
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.038
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.038
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.038
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.037
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.036
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.036
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.036
|
|
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.036
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.035
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.034
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.034
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.034
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.034
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.033
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.033
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.033
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.033
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
2 |
0.033
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.032
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.032
|
Fly |
|
|
growth
|
GO:0040007 |
174 |
0.032
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.032
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.032
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.032
|
Human |
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.032
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.031
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.031
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.031
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.030
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.030
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.030
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.030
|
|
|
|
peptide transport
|
GO:0015833 |
1 |
0.030
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.030
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.029
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.029
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.029
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.029
|
|
|
|
transport
|
GO:0006810 |
220 |
0.029
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.029
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.029
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.029
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.029
|
|
|
|
glucose homeostasis
|
GO:0042593 |
1 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.029
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
1 |
0.028
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
4 |
0.028
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.028
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.028
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.028
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.028
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.028
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.027
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.027
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
1 |
0.027
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.027
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.027
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.027
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.027
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.027
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.026
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
14 |
0.026
|
|
|
|
gastrulation
|
GO:0007369 |
208 |
0.026
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.026
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.026
|
Fly |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
2 |
0.026
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.025
|
|
|
|
pole plasm assembly
|
GO:0007315 |
4 |
0.025
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.025
|
|
|
|
head development
|
GO:0060322 |
303 |
0.025
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.025
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.025
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.025
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.025
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.025
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.025
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.025
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.025
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.025
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
1 |
0.025
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.025
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.024
|
|
|
|
protein acylation
|
GO:0043543 |
3 |
0.024
|
Human |
|
|
defense response
|
GO:0006952 |
47 |
0.024
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
1 |
0.024
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.024
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.024
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.024
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.024
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.024
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
0 |
0.023
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.023
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.023
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.023
|
|
|
|
spindle assembly
|
GO:0051225 |
2 |
0.023
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.023
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.023
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.022
|
|
|
|
rna processing
|
GO:0006396 |
25 |
0.022
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.022
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.022
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.022
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
1 |
0.022
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
16 |
0.021
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.021
|
Fly |
|
|
adherens junction assembly
|
GO:0034333 |
1 |
0.021
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.021
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.021
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
4 |
0.021
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.021
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
2 |
0.021
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.021
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.021
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.021
|
|
|
|
tissue remodeling
|
GO:0048771 |
4 |
0.021
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.021
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.021
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
53 |
0.021
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.020
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
1 |
0.020
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.020
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
2 |
0.020
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.020
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.020
|
|
|
|
lateral line development
|
GO:0048882 |
66 |
0.020
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.020
|
|
|
|
cellular component disassembly
|
GO:0022411 |
1 |
0.020
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
33 |
0.020
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.020
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.020
|
|
|
|
hormone transport
|
GO:0009914 |
2 |
0.020
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.020
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.020
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.019
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.019
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.019
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.019
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.019
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.019
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.019
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.019
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
4 |
0.019
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.019
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.019
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.019
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.019
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
1 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.019
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
1 |
0.019
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.019
|
|
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.019
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
1 |
0.019
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.019
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.018
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.018
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.018
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.018
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.018
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.018
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.018
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
1 |
0.018
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.018
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.018
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.018
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
1 |
0.018
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
2 |
0.018
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.018
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.018
|
|
|
|
renal system development
|
GO:0072001 |
94 |
0.018
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.018
|
|
|
|
response to growth factor
|
GO:0070848 |
39 |
0.018
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.018
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.018
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.018
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
1 |
0.018
|
|
|
|
female gonad development
|
GO:0008585 |
4 |
0.017
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.017
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.017
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
16 |
0.017
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.017
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.017
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
1 |
0.017
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.017
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.017
|
|
|
|
nephron development
|
GO:0072006 |
31 |
0.017
|
|
|
|
translational initiation
|
GO:0006413 |
3 |
0.017
|
|
|
|
ovulation cycle
|
GO:0042698 |
2 |
0.017
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
1 |
0.017
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
2 |
0.017
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.016
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.016
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.016
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.016
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.016
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.016
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
2 |
0.016
|
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.016
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
1 |
0.016
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.016
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.016
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.016
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.016
|
Human |
|
|
kidney development
|
GO:0001822 |
92 |
0.016
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.016
|
|
|
|
cytoplasm organization
|
GO:0007028 |
4 |
0.016
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.016
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.016
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.016
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.016
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.016
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.015
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.015
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.015
|
|
|
|
ribosome assembly
|
GO:0042255 |
1 |
0.015
|
|
|
|
urogenital system development
|
GO:0001655 |
97 |
0.015
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
1 |
0.015
|
|
|
|
response to oxidative stress
|
GO:0006979 |
11 |
0.015
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
71 |
0.015
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
1 |
0.015
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.015
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.015
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
2 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.015
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.015
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.015
|
|
|
|
ribosomal small subunit biogenesis
|
GO:0042274 |
2 |
0.015
|
|
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.015
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.015
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.015
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.015
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
2 |
0.015
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.015
|
|
|
|
protein complex disassembly
|
GO:0043241 |
1 |
0.015
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
35 |
0.015
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
3 |
0.014
|
|
|
|
rna localization
|
GO:0006403 |
4 |
0.014
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.014
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.014
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.014
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.014
|
Human Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.014
|
|
|
|
positive regulation of translation
|
GO:0045727 |
1 |
0.014
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.014
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.014
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.014
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
3 |
0.014
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.014
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
2 |
0.014
|
|
|
|
muscle system process
|
GO:0003012 |
20 |
0.014
|
|
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.014
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.014
|
|
|
|
protein secretion
|
GO:0009306 |
1 |
0.014
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
2 |
0.014
|
|
|
|
gene silencing by rna
|
GO:0031047 |
4 |
0.014
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
2 |
0.014
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
23 |
0.014
|
|
|
|
action potential
|
GO:0001508 |
19 |
0.014
|
|
|
|
locomotor rhythm
|
GO:0045475 |
3 |
0.014
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
2 |
0.014
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.014
|
|
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.014
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
2 |
0.014
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.013
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.013
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.013
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
30 |
0.013
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
2 |
0.013
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
1 |
0.013
|
|
|
|
ion homeostasis
|
GO:0050801 |
41 |
0.013
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.013
|
|
|
|
centrosome cycle
|
GO:0007098 |
1 |
0.013
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.013
|
|
|
|
heart contraction
|
GO:0060047 |
71 |
0.013
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.013
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.013
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
25 |
0.013
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
30 |
0.013
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.013
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.013
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.013
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.013
|
|
|
|
negative regulation of translation
|
GO:0017148 |
1 |
0.013
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.013
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
1 |
0.013
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
1 |
0.013
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.013
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
2 |
0.013
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.013
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.013
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.013
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.013
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.013
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.013
|
|
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.013
|
|
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
2 |
0.013
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.013
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.013
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.012
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
2 |
0.012
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.012
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.012
|
|
|
|
protein complex assembly
|
GO:0006461 |
30 |
0.012
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.012
|
Human Fly |
|
|
heart process
|
GO:0003015 |
71 |
0.012
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.012
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.012
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.012
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.012
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
4 |
0.012
|
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.012
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.012
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
4 |
0.012
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.012
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.012
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
3 |
0.012
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.012
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.012
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
21 |
0.012
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.012
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
4 |
0.012
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
2 |
0.012
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
1 |
0.012
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.012
|
|
|
|
bone remodeling
|
GO:0046849 |
2 |
0.012
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
3 |
0.012
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.012
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.012
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
3 |
0.012
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.011
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
1 |
0.011
|
|
