Danio rerio

0 known processes

napa

N-ethylmaleimide sensitive fusion protein attachment protein alpha

(Aliases: wu:fa26c04,zgc:63906)

napa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism localization GO:1902578 225 0.342
Worm
meiotic nuclear division GO:0007126 4 0.200
single organism transport GO:0044765 206 0.181
Worm
signal transduction GO:0007165 455 0.170
response to biotic stimulus GO:0009607 97 0.157
regulation of signal transduction GO:0009966 225 0.153
establishment of localization GO:0051234 244 0.144
Worm
ubiquitin dependent protein catabolic process GO:0006511 3 0.121
larval development GO:0002164 2 0.111
Worm
modification dependent protein catabolic process GO:0019941 3 0.110
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.109
response to external stimulus GO:0009605 264 0.107
phagocytosis GO:0006909 3 0.104
programmed cell death GO:0012501 119 0.103
Worm
cell death GO:0008219 121 0.100
Worm
morphogenesis of an epithelium GO:0002009 333 0.096
meiotic chromosome segregation GO:0045132 3 0.095
meiotic cell cycle process GO:1903046 3 0.095
regulation of biological quality GO:0065008 263 0.092
regulation of cell death GO:0010941 103 0.091
cellular response to nutrient levels GO:0031669 2 0.087
positive regulation of transport GO:0051050 2 0.083
regulation of cell communication GO:0010646 232 0.081
regulation of response to stimulus GO:0048583 269 0.078
regulation of signaling GO:0023051 235 0.075
modification dependent macromolecule catabolic process GO:0043632 3 0.070
cellular response to extracellular stimulus GO:0031668 2 0.068
regulation of programmed cell death GO:0043067 101 0.066
cell projection organization GO:0030030 284 0.066
cellular protein catabolic process GO:0044257 4 0.065
negative regulation of cellular process GO:0048523 283 0.063
death GO:0016265 121 0.062
Worm
cellular response to starvation GO:0009267 1 0.062
enzyme linked receptor protein signaling pathway GO:0007167 106 0.061
lipid storage GO:0019915 1 0.060
response to chemical GO:0042221 320 0.059
positive regulation of cellular catabolic process GO:0031331 3 0.056
cell surface receptor signaling pathway GO:0007166 325 0.056
cellular response to external stimulus GO:0071496 2 0.054
axonogenesis GO:0007409 152 0.052
response to decreased oxygen levels GO:0036293 25 0.051
negative regulation of biological process GO:0048519 304 0.050
gastrulation GO:0007369 208 0.048
cellular localization GO:0051641 97 0.047
Worm
regulation of protein catabolic process GO:0042176 1 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.046
mitochondrion organization GO:0007005 4 0.045
digestive system development GO:0055123 289 0.045
brain development GO:0007420 293 0.044
aging GO:0007568 2 0.043
autophagy GO:0006914 4 0.043
extrinsic apoptotic signaling pathway GO:0097191 3 0.043
response to other organism GO:0051707 97 0.042
proteasomal protein catabolic process GO:0010498 2 0.042
regulation of apoptotic process GO:0042981 98 0.041
positive regulation of biological process GO:0048518 253 0.041
growth GO:0040007 174 0.041
membrane fusion GO:0061025 2 0.040
chordate embryonic development GO:0043009 271 0.040
organic acid metabolic process GO:0006082 31 0.039
heart development GO:0007507 313 0.039
regulation of cell projection assembly GO:0060491 4 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.038
Worm
cell part morphogenesis GO:0032990 246 0.038
localization of cell GO:0051674 244 0.037
single organism metabolic process GO:0044710 217 0.037
single organism membrane fusion GO:0044801 2 0.037
tube morphogenesis GO:0035239 349 0.036
apoptotic process GO:0006915 116 0.036
Worm
cellular component movement GO:0006928 335 0.036
regulation of metal ion transport GO:0010959 4 0.035
epiboly GO:0090504 41 0.034
regulation of protein ubiquitination GO:0031396 3 0.034
stem cell division GO:0017145 1 0.034
organelle fusion GO:0048284 3 0.034
zymogen activation GO:0031638 3 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.034
maintenance of location GO:0051235 4 0.034
positive regulation of cell cycle GO:0045787 3 0.034
regulation of metabolic process GO:0019222 359 0.034
locomotion GO:0040011 313 0.032
Worm
regulation of cell development GO:0060284 100 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
multi organism process GO:0051704 134 0.031
organelle organization GO:0006996 227 0.031
transport GO:0006810 220 0.031
Worm
apoptotic process involved in development GO:1902742 2 0.031
regulation of reproductive process GO:2000241 4 0.031
endosomal transport GO:0016197 2 0.030
regulation of synapse organization GO:0050807 3 0.030
protein targeting to nucleus GO:0044744 3 0.030
cell projection morphogenesis GO:0048858 244 0.029
guanosine containing compound catabolic process GO:1901069 2 0.029
response to external biotic stimulus GO:0043207 97 0.028
cilium organization GO:0044782 71 0.028
metal ion transport GO:0030001 58 0.028
regulation of cellular metabolic process GO:0031323 320 0.027
digestive tract development GO:0048565 265 0.027
cation transport GO:0006812 81 0.027
cellular component assembly GO:0022607 170 0.027
positive regulation of catabolic process GO:0009896 4 0.027
peptide metabolic process GO:0006518 1 0.027
response to glucocorticoid GO:0051384 1 0.027
regulation of protein complex assembly GO:0043254 3 0.026
response to glucose GO:0009749 3 0.026
establishment of protein localization to plasma membrane GO:0090002 1 0.026
response to corticosteroid GO:0031960 1 0.025
cell morphogenesis GO:0000902 289 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
positive regulation of programmed cell death GO:0043068 29 0.025
digestive tract morphogenesis GO:0048546 231 0.025
response to carbohydrate GO:0009743 3 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.024
somitogenesis GO:0001756 87 0.024
macroautophagy GO:0016236 1 0.024
cell motility GO:0048870 244 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
central nervous system development GO:0007417 387 0.024
meiosis i GO:0007127 1 0.023
tissue remodeling GO:0048771 4 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
regulation of intracellular signal transduction GO:1902531 57 0.023
peptide transport GO:0015833 1 0.023
developmental programmed cell death GO:0010623 4 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
positive regulation of cellular process GO:0048522 201 0.022
carbohydrate homeostasis GO:0033500 1 0.022
neuron differentiation GO:0030182 353 0.022
embryonic limb morphogenesis GO:0030326 2 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
lateral inhibition GO:0046331 1 0.021
head development GO:0060322 303 0.021
response to nicotine GO:0035094 2 0.021
convergent extension GO:0060026 118 0.021
chromosome organization involved in meiosis GO:0070192 1 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
gastrulation with mouth forming second GO:0001702 44 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.020
hormone transport GO:0009914 2 0.020
cellular ketone metabolic process GO:0042180 11 0.020
cell migration GO:0016477 237 0.020
neurotransmitter transport GO:0006836 2 0.020
microtubule organizing center organization GO:0031023 1 0.020
synaptic vesicle transport GO:0048489 1 0.020
golgi vesicle transport GO:0048193 3 0.020
response to hexose GO:0009746 3 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
immune system process GO:0002376 241 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
neuron projection morphogenesis GO:0048812 161 0.020
cellular protein metabolic process GO:0044267 129 0.020
glucose homeostasis GO:0042593 1 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
female meiotic division GO:0007143 2 0.019
biosynthetic process GO:0009058 294 0.019
erk1 and erk2 cascade GO:0070371 4 0.019
axon development GO:0061564 166 0.019
cellular component biogenesis GO:0044085 178 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
intracellular signal transduction GO:0035556 85 0.018
regulation of response to oxidative stress GO:1902882 2 0.018
nuclear import GO:0051170 3 0.018
developmental growth GO:0048589 166 0.018
regulation of cell shape GO:0008360 1 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
cellular amine metabolic process GO:0044106 2 0.017
regulation of protein transport GO:0051223 3 0.017
response to bacterium GO:0009617 58 0.017
regulation of catalytic activity GO:0050790 55 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
hormone secretion GO:0046879 2 0.017
system process GO:0003008 185 0.017
vasculature development GO:0001944 278 0.017
response to uv GO:0009411 3 0.017
anterior posterior pattern specification GO:0009952 152 0.017
intracellular transport GO:0046907 32 0.017
heart morphogenesis GO:0003007 156 0.017
negative regulation of chemotaxis GO:0050922 4 0.017
protein metabolic process GO:0019538 183 0.017
defense response to other organism GO:0098542 33 0.017
somite development GO:0061053 96 0.017
regulation of cellular component organization GO:0051128 86 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
carboxylic acid metabolic process GO:0019752 22 0.016
macromolecule localization GO:0033036 54 0.016
multicellular organismal homeostasis GO:0048871 29 0.016
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.016
neuron projection guidance GO:0097485 86 0.016
single organism nuclear import GO:1902593 3 0.016
generation of neurons GO:0048699 385 0.016
protein localization to plasma membrane GO:0072659 1 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
lytic vacuole organization GO:0080171 1 0.016
cellular response to decreased oxygen levels GO:0036294 1 0.016
regulation of blood vessel size GO:0050880 2 0.016
neuron projection development GO:0031175 180 0.016
gtp metabolic process GO:0046039 4 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
segmentation GO:0035282 97 0.015
establishment of vesicle localization GO:0051650 24 0.015
regulation of protein targeting GO:1903533 2 0.015
positive regulation of apoptotic process GO:0043065 29 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
adult behavior GO:0030534 2 0.015
tissue homeostasis GO:0001894 25 0.015
regulation of primary metabolic process GO:0080090 311 0.015
homeostatic process GO:0042592 142 0.015
neural tube patterning GO:0021532 33 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
immune system development GO:0002520 191 0.015
oxoacid metabolic process GO:0043436 31 0.015
positive regulation of hydrolase activity GO:0051345 13 0.015
response to drug GO:0042493 3 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
protein complex biogenesis GO:0070271 30 0.014
cognition GO:0050890 1 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
cellular component morphogenesis GO:0032989 336 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
regionalization GO:0003002 274 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
protein localization to microtubule cytoskeleton GO:0072698 1 0.014
cytoskeleton organization GO:0007010 96 0.014
regulation of hormone secretion GO:0046883 2 0.014
meiotic spindle organization GO:0000212 1 0.014
gtp catabolic process GO:0006184 2 0.014
chemical homeostasis GO:0048878 49 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
cation transmembrane transport GO:0098655 65 0.013
synaptic vesicle localization GO:0097479 1 0.013
neuroblast proliferation GO:0007405 2 0.013
neurological system process GO:0050877 62 0.013
regulation of autophagy GO:0010506 3 0.013
cellular response to drug GO:0035690 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
blood vessel development GO:0001568 246 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of gtpase activity GO:0043087 2 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
negative regulation of signal transduction GO:0009968 94 0.013
lipid catabolic process GO:0016042 4 0.013
regulation of protein metabolic process GO:0051246 56 0.013
synaptic transmission GO:0007268 35 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
protein heterooligomerization GO:0051291 1 0.013
establishment of localization in cell GO:0051649 77 0.013
Worm
post embryonic organ development GO:0048569 4 0.013
negative regulation of defense response GO:0031348 2 0.013
regulation of cysteine type endopeptidase activity GO:2000116 21 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
regulation of cell size GO:0008361 29 0.013
protein localization to nucleus GO:0034504 3 0.013
protein complex subunit organization GO:0071822 46 0.013
pigment granule localization GO:0051875 25 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of cell activation GO:0050865 1 0.013
organic substance biosynthetic process GO:1901576 289 0.013
positive regulation of cell death GO:0010942 29 0.013
protein complex assembly GO:0006461 30 0.013
neuron development GO:0048666 262 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
calcium mediated signaling GO:0019722 2 0.012
stem cell maintenance GO:0019827 4 0.012
response to stress GO:0006950 263 0.012
regulation of peptidase activity GO:0052547 23 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of organ growth GO:0046620 3 0.012
negative regulation of cell death GO:0060548 60 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
glial cell migration GO:0008347 3 0.012
protein polyubiquitination GO:0000209 4 0.012
regulation of binding GO:0051098 3 0.012
organic substance transport GO:0071702 58 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.012
cell cycle process GO:0022402 53 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
response to alkaloid GO:0043279 2 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
centrosome cycle GO:0007098 1 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
negative regulation of secretion GO:0051048 2 0.012
regulation of synapse assembly GO:0051963 3 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
proteolysis GO:0006508 38 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
cytokinesis GO:0000910 3 0.011
protein import GO:0017038 3 0.011
small molecule metabolic process GO:0044281 77 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
chromosome segregation GO:0007059 12 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cell cell signaling GO:0007267 52 0.011
pigment granule transport GO:0051904 19 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
regulation of cytokine production GO:0001817 3 0.011
positive regulation of molecular function GO:0044093 33 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.010
lysosomal transport GO:0007041 2 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
cellular component disassembly GO:0022411 1 0.010
regulation of developmental process GO:0050793 247 0.010
regulation of endopeptidase activity GO:0052548 23 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
positive regulation of metabolic process GO:0009893 108 0.010
ion transport GO:0006811 114 0.010
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.010
response to monosaccharide GO:0034284 3 0.010
vesicle localization GO:0051648 27 0.010
tissue regeneration GO:0042246 74 0.010
protein homooligomerization GO:0051260 3 0.010
blood circulation GO:0008015 87 0.010
cellular amide metabolic process GO:0043603 4 0.010
organelle localization GO:0051640 49 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010
cellular response to oxygen levels GO:0071453 1 0.010
negative regulation of kinase activity GO:0033673 4 0.010
organelle assembly GO:0070925 110 0.010
neurotransmitter secretion GO:0007269 2 0.010

napa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.013
colon carcinoma DOID:1520 0 0.010
large intestine cancer DOID:5672 0 0.010
colon cancer DOID:219 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010
intestinal cancer DOID:10155 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010
colorectal cancer DOID:9256 0 0.010