Danio rerio

30 known processes

nar

no arches

nar biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.199
cellular component assembly GO:0022607 170 0.125
organic cyclic compound metabolic process GO:1901360 301 0.107
biosynthetic process GO:0009058 294 0.095
macromolecule modification GO:0043412 111 0.081
regulation of macromolecule metabolic process GO:0060255 317 0.077
organelle organization GO:0006996 227 0.077
nucleic acid metabolic process GO:0090304 244 0.071
nitrogen compound metabolic process GO:0006807 319 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.066
regulation of metabolic process GO:0019222 359 0.064
cellular macromolecule metabolic process GO:0044260 391 0.064
gene expression GO:0010467 252 0.063
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.063
nucleobase containing compound metabolic process GO:0006139 274 0.063
cellular biosynthetic process GO:0044249 286 0.061
response to external stimulus GO:0009605 264 0.061
protein metabolic process GO:0019538 183 0.059
single organism metabolic process GO:0044710 217 0.058
cellular protein metabolic process GO:0044267 129 0.057
negative regulation of nuclear division GO:0051784 3 0.056
cellular component biogenesis GO:0044085 178 0.055
cellular amino acid metabolic process GO:0006520 7 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.048
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.046
negative regulation of biological process GO:0048519 304 0.046
Worm
regulation of binding GO:0051098 3 0.046
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.046
locomotion GO:0040011 313 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.045
macromolecule biosynthetic process GO:0009059 227 0.045
amine metabolic process GO:0009308 2 0.045
heterocycle metabolic process GO:0046483 290 0.045
response to stress GO:0006950 263 0.044
protein localization to nucleus GO:0034504 3 0.044
meiotic chromosome segregation GO:0045132 3 0.042
nuclear transport GO:0051169 4 0.042
rna biosynthetic process GO:0032774 181 0.041
meiosis i GO:0007127 1 0.040
aromatic compound biosynthetic process GO:0019438 217 0.039
regulation of protein ubiquitination GO:0031396 3 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
female meiotic division GO:0007143 2 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
cellular response to molecule of bacterial origin GO:0071219 3 0.038
positive regulation of catabolic process GO:0009896 4 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.037
autophagy GO:0006914 4 0.037
cellular amine metabolic process GO:0044106 2 0.037
ganglioside metabolic process GO:0001573 3 0.037
organic acid metabolic process GO:0006082 31 0.037
nucleic acid transport GO:0050657 2 0.036
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
regulation of nucleic acid templated transcription GO:1903506 213 0.036
morphogenesis of an epithelium GO:0002009 333 0.035
regulation of meiotic cell cycle GO:0051445 1 0.035
oxoacid metabolic process GO:0043436 31 0.034
camera type eye development GO:0043010 222 0.034
regulation of protein complex assembly GO:0043254 3 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.033
brain development GO:0007420 293 0.033
regulation of rna metabolic process GO:0051252 224 0.033
positive regulation of notch signaling pathway GO:0045747 3 0.033
phagocytosis GO:0006909 3 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.032
positive regulation of cellular process GO:0048522 201 0.032
meiotic cell cycle process GO:1903046 3 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
heart development GO:0007507 313 0.031
hemopoiesis GO:0030097 183 0.030
central nervous system development GO:0007417 387 0.030
g1 s transition of mitotic cell cycle GO:0000082 1 0.030
mitotic cell cycle GO:0000278 64 0.030
rna metabolic process GO:0016070 219 0.030
cell projection assembly GO:0030031 64 0.029
regulation of epithelial cell proliferation GO:0050678 3 0.029
protein targeting to nucleus GO:0044744 3 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
cell cycle g1 s phase transition GO:0044843 1 0.029
regulation of cellular component organization GO:0051128 86 0.029
spindle assembly GO:0051225 2 0.029
cellular protein modification process GO:0006464 100 0.029
membrane lipid biosynthetic process GO:0046467 2 0.029
regulation of gene expression GO:0010468 265 0.029
positive regulation of apoptotic signaling pathway GO:2001235 1 0.028
gtp catabolic process GO:0006184 2 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
mitochondrion organization GO:0007005 4 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
positive regulation of transport GO:0051050 2 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
mrna transport GO:0051028 2 0.026
organic substance biosynthetic process GO:1901576 289 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
regulation of mitochondrion organization GO:0010821 1 0.026
protein modification process GO:0036211 100 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
cell cycle GO:0007049 93 0.026
maintenance of location GO:0051235 4 0.026
single organism organelle organization GO:1902589 199 0.026
response to chemical GO:0042221 320 0.026
response to uv GO:0009411 3 0.026
protein import into nucleus GO:0006606 3 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.026
establishment of rna localization GO:0051236 3 0.025
regulation of biosynthetic process GO:0009889 250 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
rna transport GO:0050658 2 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
histone modification GO:0016570 20 0.025
nucleic acid templated transcription GO:0097659 181 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
developmental programmed cell death GO:0010623 4 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
regulation of primary metabolic process GO:0080090 311 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
protein acylation GO:0043543 3 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
protein polymerization GO:0051258 4 0.024
mitotic dna integrity checkpoint GO:0044774 4 0.024
eye development GO:0001654 277 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of developmental process GO:0050793 247 0.024
Worm
positive regulation of protein complex assembly GO:0031334 2 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
signal transduction GO:0007165 455 0.023
transcription dna templated GO:0006351 181 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
nucleobase containing compound transport GO:0015931 2 0.023
cell projection organization GO:0030030 284 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
cellular protein catabolic process GO:0044257 4 0.023
protein sumoylation GO:0016925 2 0.023
alpha amino acid metabolic process GO:1901605 3 0.022
cellular component movement GO:0006928 335 0.022
single organism nuclear import GO:1902593 3 0.022
protein n linked glycosylation GO:0006487 1 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
aging GO:0007568 2 0.022
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
rna 3 end processing GO:0031123 2 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
cell aging GO:0007569 2 0.022
cellular component disassembly GO:0022411 1 0.022
regulation of protein transport GO:0051223 3 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
myeloid cell homeostasis GO:0002262 56 0.021
smoothened signaling pathway GO:0007224 30 0.021
retina development in camera type eye GO:0060041 146 0.021
immune system development GO:0002520 191 0.021
regulation of chromosome segregation GO:0051983 1 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
larval development GO:0002164 2 0.020
Worm
centrosome organization GO:0051297 1 0.020
protein import GO:0017038 3 0.020
nuclear import GO:0051170 3 0.020
sialylation GO:0097503 4 0.020
axonogenesis GO:0007409 152 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
stem cell maintenance GO:0019827 4 0.020
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
glycolipid biosynthetic process GO:0009247 1 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
erythrocyte differentiation GO:0030218 54 0.019
cellular response to stress GO:0033554 62 0.019
macromolecular complex assembly GO:0065003 35 0.019
taxis GO:0042330 109 0.019
macromolecule glycosylation GO:0043413 9 0.019
liver development GO:0001889 96 0.019
positive regulation of epithelial cell proliferation GO:0050679 1 0.019
transport GO:0006810 220 0.019
ceramide biosynthetic process GO:0046513 1 0.019
positive regulation of secretion GO:0051047 1 0.019
regulation of response to stimulus GO:0048583 269 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
regulation of signaling GO:0023051 235 0.018
response to other organism GO:0051707 97 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
homeostasis of number of cells GO:0048872 62 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of cytokine production GO:0001817 3 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of transcription dna templated GO:0006355 213 0.018
sphingolipid biosynthetic process GO:0030148 2 0.018
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.018
multicellular organism growth GO:0035264 4 0.018
single organism membrane fusion GO:0044801 2 0.018
fertilization GO:0009566 3 0.017
protein localization to plasma membrane GO:0072659 1 0.017
immune system process GO:0002376 241 0.017
cell part morphogenesis GO:0032990 246 0.017
membrane fusion GO:0061025 2 0.017
cytoskeleton organization GO:0007010 96 0.017
regulation of synapse assembly GO:0051963 3 0.017
regulation of signal transduction by p53 class mediator GO:1901796 9 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
Worm
meiotic spindle organization GO:0000212 1 0.017
negative regulation of cytokine production GO:0001818 1 0.017
single organism localization GO:1902578 225 0.017
estrogen metabolic process GO:0008210 2 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
tube morphogenesis GO:0035239 349 0.017
positive regulation of cytokine production GO:0001819 2 0.016
actin filament polymerization GO:0030041 2 0.016
regulation of cell activation GO:0050865 1 0.016
muscle structure development GO:0061061 196 0.016
activation of mapk activity GO:0000187 3 0.016
mrna 3 end processing GO:0031124 2 0.016
neurotransmitter transport GO:0006836 2 0.016
positive regulation of cell cycle GO:0045787 3 0.016
spindle assembly involved in meiosis GO:0090306 1 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
mononuclear cell proliferation GO:0032943 1 0.016
stem cell proliferation GO:0072089 4 0.016
cytokinesis GO:0000910 3 0.016
head development GO:0060322 303 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.016
small molecule metabolic process GO:0044281 77 0.015
regulation of biological quality GO:0065008 263 0.015
regulation of cell projection assembly GO:0060491 4 0.015
apoptotic process involved in development GO:1902742 2 0.015
regulation of protein metabolic process GO:0051246 56 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
generation of neurons GO:0048699 385 0.015
neuroblast proliferation GO:0007405 2 0.015
leukocyte proliferation GO:0070661 1 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
digestive system development GO:0055123 289 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of organ growth GO:0046620 3 0.015
negative regulation of mitosis GO:0045839 3 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
nuclear division GO:0000280 23 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
cellular response to radiation GO:0071478 4 0.015
cell projection morphogenesis GO:0048858 244 0.015
lymphocyte proliferation GO:0046651 1 0.015
erythrocyte homeostasis GO:0034101 55 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
rna polyadenylation GO:0043631 2 0.015
myeloid cell differentiation GO:0030099 86 0.015
renal tubule morphogenesis GO:0061333 1 0.015
protein acetylation GO:0006473 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
single organism transport GO:0044765 206 0.015
rna processing GO:0006396 25 0.015
negative regulation of protein kinase activity GO:0006469 4 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
regulation of protein binding GO:0043393 3 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
regulation of autophagy GO:0010506 3 0.014
gland development GO:0048732 143 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
meiosis ii GO:0007135 1 0.014
regulation of synapse organization GO:0050807 3 0.014
single organism biosynthetic process GO:0044711 71 0.014
organelle fusion GO:0048284 3 0.014
spermatid differentiation GO:0048515 2 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
heart morphogenesis GO:0003007 156 0.014
positive regulation of signal transduction GO:0009967 56 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
response to lipid GO:0033993 60 0.013
germ line stem cell division GO:0042078 1 0.013
regulation of molecular function GO:0065009 70 0.013
response to organic substance GO:0010033 153 0.013
rna modification GO:0009451 2 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
lipid storage GO:0019915 1 0.013
primary neural tube formation GO:0014020 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
rna localization GO:0006403 4 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
reciprocal dna recombination GO:0035825 1 0.013
hepaticobiliary system development GO:0061008 98 0.013
regulation of dna replication GO:0006275 3 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
protein secretion GO:0009306 1 0.013
sister chromatid cohesion GO:0007062 2 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
cellular response to starvation GO:0009267 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
positive regulation of muscle tissue development GO:1901863 1 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
axon development GO:0061564 166 0.013
protein stabilization GO:0050821 2 0.013
cellular component morphogenesis GO:0032989 336 0.013
heart looping GO:0001947 94 0.012
regulation of gtpase activity GO:0043087 2 0.012
nuclear export GO:0051168 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
positive regulation of neuron death GO:1901216 1 0.012
reciprocal meiotic recombination GO:0007131 1 0.012
cell morphogenesis GO:0000902 289 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
establishment of localization GO:0051234 244 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
glycosphingolipid biosynthetic process GO:0006688 1 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
positive regulation of leukocyte migration GO:0002687 2 0.012
negative regulation of leukocyte differentiation GO:1902106 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
adherens junction organization GO:0034332 4 0.012
regulation of protein targeting GO:1903533 2 0.012
cellular response to oxygen levels GO:0071453 1 0.012
centrosome cycle GO:0007098 1 0.012
negative regulation of cellular process GO:0048523 283 0.012
cell cycle process GO:0022402 53 0.012
tube closure GO:0060606 1 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
histone deacetylation GO:0016575 2 0.012
defense response to bacterium GO:0042742 22 0.012
somatic stem cell maintenance GO:0035019 1 0.012
xenobiotic metabolic process GO:0006805 4 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
protein complex assembly GO:0006461 30 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
neuronal action potential GO:0019228 18 0.011
regulation of signal transduction GO:0009966 225 0.011
female gonad development GO:0008585 4 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of organelle organization GO:0033043 29 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
positive regulation of embryonic development GO:0040019 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
digestive tract development GO:0048565 265 0.011
protein complex biogenesis GO:0070271 30 0.011
chemotaxis GO:0006935 104 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
urogenital system development GO:0001655 97 0.011
renal system development GO:0072001 94 0.011
organ regeneration GO:0031100 1 0.011
homeostatic process GO:0042592 142 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
protein dephosphorylation GO:0006470 3 0.011
intracellular signal transduction GO:0035556 85 0.011
glycoprotein biosynthetic process GO:0009101 21 0.011
compound eye development GO:0048749 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
response to drug GO:0042493 3 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
pronuclear migration GO:0035046 1 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
macromolecule localization GO:0033036 54 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
osteoclast differentiation GO:0030316 1 0.011
eye morphogenesis GO:0048592 144 0.010
zymogen activation GO:0031638 3 0.010
neuron differentiation GO:0030182 353 0.010
neuron projection development GO:0031175 180 0.010
response to corticosteroid GO:0031960 1 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
membrane invagination GO:0010324 1 0.010
nephron morphogenesis GO:0072028 2 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
Worm
regulation of type i interferon production GO:0032479 2 0.010
embryonic organ development GO:0048568 381 0.010
cellular response to hypoxia GO:0071456 1 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010
negative regulation of signaling GO:0023057 96 0.010
cellular localization GO:0051641 97 0.010
atp catabolic process GO:0006200 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010

nar disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.023
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011