Danio rerio

0 known processes

nek4

NIMA (never in mitosis gene a)-related kinase 4

(Aliases: MGC64176,zgc:64176)

nek4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.232
Mouse
larval development GO:0002164 2 0.200
cellular nitrogen compound metabolic process GO:0034641 290 0.073
heterocycle metabolic process GO:0046483 290 0.072
central nervous system development GO:0007417 387 0.069
organic cyclic compound metabolic process GO:1901360 301 0.061
meiotic nuclear division GO:0007126 4 0.061
cellular protein metabolic process GO:0044267 129 0.061
Mouse
generation of neurons GO:0048699 385 0.057
nucleic acid metabolic process GO:0090304 244 0.051
macromolecule biosynthetic process GO:0009059 227 0.051
brain development GO:0007420 293 0.051
single organism metabolic process GO:0044710 217 0.050
aging GO:0007568 2 0.050
Human
nitrogen compound metabolic process GO:0006807 319 0.049
cellular ketone metabolic process GO:0042180 11 0.049
biosynthetic process GO:0009058 294 0.047
protein targeting to nucleus GO:0044744 3 0.046
nucleocytoplasmic transport GO:0006913 4 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
negative regulation of cellular process GO:0048523 283 0.043
nuclear transport GO:0051169 4 0.042
organelle organization GO:0006996 227 0.042
establishment of protein localization to organelle GO:0072594 4 0.041
regulation of signaling GO:0023051 235 0.040
protein modification process GO:0036211 100 0.040
Mouse
single organism transport GO:0044765 206 0.040
meiotic cell cycle process GO:1903046 3 0.039
regulation of signal transduction GO:0009966 225 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
protein metabolic process GO:0019538 183 0.036
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.034
protein import into nucleus GO:0006606 3 0.033
macromolecule modification GO:0043412 111 0.032
Mouse
multi organism process GO:0051704 134 0.031
establishment of localization GO:0051234 244 0.031
cellular biosynthetic process GO:0044249 286 0.030
rna metabolic process GO:0016070 219 0.030
signal transduction GO:0007165 455 0.029
maintenance of location GO:0051235 4 0.029
positive regulation of transport GO:0051050 2 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
response to stress GO:0006950 263 0.027
Human
amine metabolic process GO:0009308 2 0.027
single organism nuclear import GO:1902593 3 0.027
regulation of protein transport GO:0051223 3 0.027
regulation of primary metabolic process GO:0080090 311 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
nuclear import GO:0051170 3 0.026
cellular amine metabolic process GO:0044106 2 0.026
regulation of synapse organization GO:0050807 3 0.026
negative regulation of response to stimulus GO:0048585 104 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
transport GO:0006810 220 0.025
protein localization to nucleus GO:0034504 3 0.025
positive regulation of cellular process GO:0048522 201 0.025
cellular protein modification process GO:0006464 100 0.024
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.024
regulation of response to stimulus GO:0048583 269 0.024
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
positive regulation of biological process GO:0048518 253 0.024
head development GO:0060322 303 0.023
cellular localization GO:0051641 97 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
negative regulation of biological process GO:0048519 304 0.023
regulation of binding GO:0051098 3 0.023
organic substance biosynthetic process GO:1901576 289 0.023
membrane lipid biosynthetic process GO:0046467 2 0.023
response to drug GO:0042493 3 0.023
multicellular organism growth GO:0035264 4 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
cell death GO:0008219 121 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
homeostatic process GO:0042592 142 0.022
regulation of response to cytokine stimulus GO:0060759 3 0.022
cell migration GO:0016477 237 0.021
protein import GO:0017038 3 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
positive regulation of catabolic process GO:0009896 4 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
Mouse
apoptotic process GO:0006915 116 0.021
cellular lipid metabolic process GO:0044255 36 0.021
negative regulation of cell death GO:0060548 60 0.020
cell motility GO:0048870 244 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
cellular component movement GO:0006928 335 0.020
negative regulation of cell communication GO:0010648 96 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
b cell activation GO:0042113 2 0.019
fertilization GO:0009566 3 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
gene expression GO:0010467 252 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
g2 dna damage checkpoint GO:0031572 3 0.018
regulation of synapse assembly GO:0051963 3 0.018
regulation of biological quality GO:0065008 263 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
negative regulation of signal transduction GO:0009968 94 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of cell communication GO:0010646 232 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
adult behavior GO:0030534 2 0.017
locomotion GO:0040011 313 0.017
single organism localization GO:1902578 225 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
regulation of cell activation GO:0050865 1 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
regulation of metabolic process GO:0019222 359 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
immune system process GO:0002376 241 0.016
response to corticosteroid GO:0031960 1 0.016
positive regulation of cell activation GO:0050867 1 0.016
negative regulation of response to cytokine stimulus GO:0060761 2 0.016
regulation of biosynthetic process GO:0009889 250 0.016
transcription dna templated GO:0006351 181 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
localization of cell GO:0051674 244 0.016
response to organic substance GO:0010033 153 0.016
negative regulation of defense response GO:0031348 2 0.016
small molecule metabolic process GO:0044281 77 0.016
regulation of cytokine mediated signaling pathway GO:0001959 3 0.016
regulation of jak stat cascade GO:0046425 3 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
positive regulation of cell division GO:0051781 2 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.015
neuron differentiation GO:0030182 353 0.015
regulation of developmental process GO:0050793 247 0.015
Human
membrane invagination GO:0010324 1 0.015
oxoacid metabolic process GO:0043436 31 0.015
sensory organ development GO:0007423 393 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
cellular response to radiation GO:0071478 4 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
regulation of protein targeting GO:1903533 2 0.015
glycolipid biosynthetic process GO:0009247 1 0.014
single organism organelle organization GO:1902589 199 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of rna metabolic process GO:0051252 224 0.014
developmental process involved in reproduction GO:0003006 27 0.014
response to monosaccharide GO:0034284 3 0.014
cellular protein catabolic process GO:0044257 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
cilium morphogenesis GO:0060271 85 0.014
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.014
cilium assembly GO:0042384 58 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
response to hexose GO:0009746 3 0.013
hindbrain development GO:0030902 91 0.013
organic substance transport GO:0071702 58 0.013
glycerolipid biosynthetic process GO:0045017 1 0.013
vacuolar transport GO:0007034 2 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
forebrain cell migration GO:0021885 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
cellular response to organic substance GO:0071310 105 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
death GO:0016265 121 0.013
rna biosynthetic process GO:0032774 181 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
regulation of protein catabolic process GO:0042176 1 0.013
negative regulation of immune response GO:0050777 2 0.012
regulation of protein metabolic process GO:0051246 56 0.012
cell projection morphogenesis GO:0048858 244 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
cellular response to light stimulus GO:0071482 4 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
tube closure GO:0060606 1 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
acylglycerol homeostasis GO:0055090 2 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
organelle assembly GO:0070925 110 0.012
leukocyte proliferation GO:0070661 1 0.012
lipid storage GO:0019915 1 0.011
tyrosine phosphorylation of stat protein GO:0007260 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
primary neural tube formation GO:0014020 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
nuclear export GO:0051168 1 0.011
protein acylation GO:0043543 3 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cellular response to stress GO:0033554 62 0.011
Human
chromosome organization involved in meiosis GO:0070192 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
regulation of cell shape GO:0008360 1 0.011
tube morphogenesis GO:0035239 349 0.011
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 4 0.011
negative regulation of signaling GO:0023057 96 0.011
mitochondrion organization GO:0007005 4 0.011
determination of bilateral symmetry GO:0009855 204 0.011
Zebrafish
triglyceride homeostasis GO:0070328 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
mitotic cell cycle GO:0000278 64 0.011
Human
programmed cell death GO:0012501 119 0.011
digestive system development GO:0055123 289 0.011
protein localization to plasma membrane GO:0072659 1 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
histone h3 k4 methylation GO:0051568 2 0.010
positive regulation of cell cycle GO:0045787 3 0.010
response to nutrient GO:0007584 3 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
protein phosphorylation GO:0006468 47 0.010
Mouse
regulation of wnt signaling pathway GO:0030111 53 0.010
response to external stimulus GO:0009605 264 0.010
regulation of lipid transport GO:0032368 4 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
transmembrane transport GO:0055085 120 0.010
regulation of chromosome segregation GO:0051983 1 0.010
catecholamine metabolic process GO:0006584 2 0.010
mitotic g2 m transition checkpoint GO:0044818 3 0.010
response to nicotine GO:0035094 2 0.010
hormone transport GO:0009914 2 0.010
regulation of cell division GO:0051302 12 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
cell part morphogenesis GO:0032990 246 0.010

nek4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
musculoskeletal system disease DOID:17 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012