Danio rerio

33 known processes

nexn

nexilin (F actin binding protein)

(Aliases: MGC103442,zgc:103442)

nexn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 196 0.269
modification dependent protein catabolic process GO:0019941 3 0.267
ubiquitin dependent protein catabolic process GO:0006511 3 0.211
cellular component biogenesis GO:0044085 178 0.190
aging GO:0007568 2 0.186
striated muscle cell differentiation GO:0051146 129 0.152
determination of bilateral symmetry GO:0009855 204 0.148
cardiac muscle cell development GO:0055013 20 0.145
response to external stimulus GO:0009605 264 0.144
muscle cell development GO:0055001 115 0.141
circadian sleep wake cycle GO:0042745 2 0.132
digestive tract development GO:0048565 265 0.126
signal transduction GO:0007165 455 0.116
cellular component movement GO:0006928 335 0.101
Human
proteasomal protein catabolic process GO:0010498 2 0.094
organelle assembly GO:0070925 110 0.091
heart looping GO:0001947 94 0.090
regulation of cell projection assembly GO:0060491 4 0.087
neuron development GO:0048666 262 0.087
positive regulation of blood circulation GO:1903524 2 0.085
heart morphogenesis GO:0003007 156 0.083
neuron differentiation GO:0030182 353 0.082
cardiac ventricle formation GO:0003211 1 0.080
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.078
regulation of skeletal muscle fiber development GO:0048742 2 0.077
localization of cell GO:0051674 244 0.075
Human
ventricular cardiac muscle cell differentiation GO:0055012 6 0.072
striated muscle cell development GO:0055002 108 0.072
digestive tract morphogenesis GO:0048546 231 0.071
generation of neurons GO:0048699 385 0.071
regulation of response to stimulus GO:0048583 269 0.071
cardiac myofibril assembly GO:0055003 9 0.071
cell substrate adhesion GO:0031589 4 0.070
cellular protein catabolic process GO:0044257 4 0.069
central nervous system development GO:0007417 387 0.069
regulation of myotube differentiation GO:0010830 2 0.068
cell projection morphogenesis GO:0048858 244 0.068
heart development GO:0007507 313 0.061
positive regulation of heart contraction GO:0045823 2 0.058
embryonic heart tube morphogenesis GO:0003143 108 0.057
cellular component assembly GO:0022607 170 0.056
positive regulation of muscle organ development GO:0048636 1 0.055
regulation of filopodium assembly GO:0051489 2 0.055
striated muscle tissue development GO:0014706 110 0.054
monovalent inorganic cation transport GO:0015672 42 0.053
transmembrane transport GO:0055085 120 0.053
regulation of cell shape GO:0008360 1 0.052
circadian sleep wake cycle process GO:0022410 2 0.052
system process GO:0003008 185 0.051
cell matrix adhesion GO:0007160 4 0.050
regulation of system process GO:0044057 40 0.050
regulation of neurogenesis GO:0050767 87 0.050
negative regulation of protein phosphorylation GO:0001933 4 0.049
cell part morphogenesis GO:0032990 246 0.048
cell projection organization GO:0030030 284 0.048
ventricular cardiac myofibril assembly GO:0055005 4 0.048
taxis GO:0042330 109 0.048
rna localization GO:0006403 4 0.046
cellular response to hormone stimulus GO:0032870 39 0.046
tube morphogenesis GO:0035239 349 0.045
nucleic acid transport GO:0050657 2 0.044
muscle organ development GO:0007517 101 0.044
lipid storage GO:0019915 1 0.044
rna transport GO:0050658 2 0.043
cell morphogenesis involved in differentiation GO:0000904 195 0.043
cell surface receptor signaling pathway GO:0007166 325 0.042
single organism transport GO:0044765 206 0.042
cellular component assembly involved in morphogenesis GO:0010927 107 0.041
regulation of signal transduction GO:0009966 225 0.041
cardiac muscle cell differentiation GO:0055007 30 0.041
cytoskeleton organization GO:0007010 96 0.041
Human
cellular component morphogenesis GO:0032989 336 0.041
multicellular organismal signaling GO:0035637 22 0.039
mitotic cell cycle embryonic GO:0045448 2 0.039
larval development GO:0002164 2 0.038
response to glucocorticoid GO:0051384 1 0.037
regulation of multicellular organismal process GO:0051239 277 0.037
muscle cell differentiation GO:0042692 139 0.036
regulation of cell communication GO:0010646 232 0.036
nucleic acid metabolic process GO:0090304 244 0.036
response to hexose GO:0009746 3 0.035
regulation of signaling GO:0023051 235 0.035
nucleobase containing compound transport GO:0015931 2 0.035
regulation of membrane potential GO:0042391 23 0.034
mechanosensory behavior GO:0007638 2 0.034
chemotaxis GO:0006935 104 0.034
cell morphogenesis GO:0000902 289 0.034
regulation of ion transmembrane transporter activity GO:0032412 2 0.033
regulation of reproductive process GO:2000241 4 0.033
regulation of binding GO:0051098 3 0.033
maintenance of location GO:0051235 4 0.033
heterocycle metabolic process GO:0046483 290 0.032
regulation of reactive oxygen species metabolic process GO:2000377 2 0.032
muscle tissue development GO:0060537 110 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
oxoacid metabolic process GO:0043436 31 0.031
neurotransmitter transport GO:0006836 2 0.031
determination of heart left right asymmetry GO:0061371 117 0.031
intracellular signal transduction GO:0035556 85 0.029
positive regulation of skeletal muscle tissue development GO:0048643 1 0.029
cell motility GO:0048870 244 0.029
Human
gastrulation GO:0007369 208 0.029
negative regulation of cellular process GO:0048523 283 0.029
cardiac muscle tissue development GO:0048738 48 0.029
transmission of nerve impulse GO:0019226 19 0.029
somite development GO:0061053 96 0.028
cell projection assembly GO:0030031 64 0.028
determination of left right symmetry GO:0007368 179 0.028
transport GO:0006810 220 0.027
neuron projection development GO:0031175 180 0.027
positive regulation of transport GO:0051050 2 0.027
negative regulation of biological process GO:0048519 304 0.026
branching morphogenesis of a nerve GO:0048755 4 0.026
digestive system development GO:0055123 289 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
sleep GO:0030431 1 0.026
neural crest formation GO:0014029 14 0.025
action potential GO:0001508 19 0.025
negative regulation of phosphate metabolic process GO:0045936 13 0.025
embryonic organ development GO:0048568 381 0.024
long chain fatty acid biosynthetic process GO:0042759 1 0.024
axon development GO:0061564 166 0.024
negative regulation of catalytic activity GO:0043086 21 0.024
endocardial cushion morphogenesis GO:0003203 3 0.024
regulation of dendrite development GO:0050773 3 0.024
regulation of protein complex assembly GO:0043254 3 0.023
cell adhesion GO:0007155 40 0.023
cellular ketone metabolic process GO:0042180 11 0.023
multicellular organismal response to stress GO:0033555 2 0.023
intermediate mesoderm development GO:0048389 2 0.022
female sex differentiation GO:0046660 4 0.022
regulation of transporter activity GO:0032409 2 0.022
convergent extension GO:0060026 118 0.022
specification of symmetry GO:0009799 204 0.021
inorganic ion transmembrane transport GO:0098660 57 0.021
actin filament based process GO:0030029 64 0.021
response to corticosteroid GO:0031960 1 0.021
actin cytoskeleton organization GO:0030036 63 0.021
organic acid metabolic process GO:0006082 31 0.021
microtubule organizing center organization GO:0031023 1 0.021
cognition GO:0050890 1 0.021
myofibril assembly GO:0030239 48 0.021
regulation of membrane repolarization GO:0060306 1 0.021
translational initiation GO:0006413 3 0.021
fertilization GO:0009566 3 0.021
positive regulation of biological process GO:0048518 253 0.020
regulation of cardiac muscle contraction GO:0055117 2 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.020
regulation of cardiac muscle tissue development GO:0055024 1 0.020
chemosensory behavior GO:0007635 1 0.020
cell proliferation GO:0008283 80 0.020
circadian sleep wake cycle sleep GO:0050802 1 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of protein binding GO:0043393 3 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
cellular biosynthetic process GO:0044249 286 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
neurological system process GO:0050877 62 0.018
locomotion GO:0040011 313 0.018
Human
regulation of cytokine production GO:0001817 3 0.018
adherens junction organization GO:0034332 4 0.018
regulation of cell matrix adhesion GO:0001952 1 0.018
ion transport GO:0006811 114 0.018
axoneme assembly GO:0035082 9 0.018
muscle hypertrophy GO:0014896 2 0.018
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
alternative mrna splicing via spliceosome GO:0000380 1 0.018
neuron projection guidance GO:0097485 86 0.018
cardiac cell development GO:0055006 21 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
regulation of biological quality GO:0065008 263 0.017
regulation of gene expression GO:0010468 265 0.017
cell migration GO:0016477 237 0.017
Human
regulation of sarcomere organization GO:0060297 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
atrial cardiac myofibril assembly GO:0055004 2 0.017
spermatid development GO:0007286 2 0.017
single organism organelle organization GO:1902589 199 0.017
negative regulation of translation GO:0017148 1 0.017
response to ketone GO:1901654 1 0.017
amine metabolic process GO:0009308 2 0.017
regulation of receptor activity GO:0010469 2 0.017
response to glucose GO:0009749 3 0.017
regulation of metal ion transport GO:0010959 4 0.017
cellular protein metabolic process GO:0044267 129 0.017
nitrogen compound metabolic process GO:0006807 319 0.016
cellular protein modification process GO:0006464 100 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
establishment of rna localization GO:0051236 3 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
anterior posterior pattern specification GO:0009952 152 0.016
myotube differentiation GO:0014902 45 0.016
biological adhesion GO:0022610 40 0.016
negative regulation of developmental process GO:0051093 65 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
small molecule metabolic process GO:0044281 77 0.016
regulation of cell projection organization GO:0031344 44 0.016
meiotic nuclear division GO:0007126 4 0.016
organelle organization GO:0006996 227 0.016
Human
cellular response to starvation GO:0009267 1 0.016
heart process GO:0003015 71 0.016
regulation of blood circulation GO:1903522 32 0.016
somatic muscle development GO:0007525 4 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
positive regulation of cell cycle GO:0045787 3 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
head development GO:0060322 303 0.015
response to carbohydrate GO:0009743 3 0.015
establishment of protein localization to organelle GO:0072594 4 0.014
response to chemical GO:0042221 320 0.014
post embryonic organ development GO:0048569 4 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
protein targeting to membrane GO:0006612 1 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
cellular response to oxygen containing compound GO:1901701 20 0.014
cellular response to organic substance GO:0071310 105 0.014
regulation of ion transmembrane transport GO:0034765 18 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
response to oxygen containing compound GO:1901700 55 0.014
regulation of neurological system process GO:0031644 2 0.014
skeletal muscle tissue development GO:0007519 67 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
protein metabolic process GO:0019538 183 0.013
positive regulation of muscle tissue development GO:1901863 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
response to stress GO:0006950 263 0.013
neurotransmitter secretion GO:0007269 2 0.013
stem cell proliferation GO:0072089 4 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
connective tissue development GO:0061448 99 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of cell development GO:0060284 100 0.013
pigmentation GO:0043473 85 0.013
cardiocyte differentiation GO:0035051 44 0.013
response to nutrient GO:0007584 3 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
multi organism process GO:0051704 134 0.013
single organism biosynthetic process GO:0044711 71 0.013
immune system process GO:0002376 241 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of neurotransmitter transport GO:0051588 1 0.012
establishment of localization GO:0051234 244 0.012
single organism metabolic process GO:0044710 217 0.012
mrna transport GO:0051028 2 0.012
regulation of cellular component organization GO:0051128 86 0.012
Human
smad protein complex assembly GO:0007183 1 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
cellular response to lipid GO:0071396 39 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
membrane repolarization GO:0086009 2 0.012
regulation of jak stat cascade GO:0046425 3 0.012
cardiac conduction system development GO:0003161 1 0.012
gene expression GO:0010467 252 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
cellular lipid metabolic process GO:0044255 36 0.012
somitogenesis GO:0001756 87 0.012
endocardial cushion formation GO:0003272 2 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
stem cell differentiation GO:0048863 117 0.011
muscle fiber development GO:0048747 52 0.011
endocardial cushion development GO:0003197 6 0.011
negative regulation of cell communication GO:0010648 96 0.011
limb bud formation GO:0060174 2 0.011
regulation of bone mineralization GO:0030500 2 0.011
cardiac muscle fiber development GO:0048739 3 0.011
lipid homeostasis GO:0055088 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
actin filament based movement GO:0030048 1 0.011
adult behavior GO:0030534 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
sexual reproduction GO:0019953 36 0.011
single organism localization GO:1902578 225 0.011
response to lipid GO:0033993 60 0.011
translation GO:0006412 5 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
protein import GO:0017038 3 0.011
mrna metabolic process GO:0016071 20 0.011
regulation of blood pressure GO:0008217 1 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of programmed cell death GO:0043067 101 0.010
atrial cardiac muscle cell development GO:0055014 4 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
blood vessel development GO:0001568 246 0.010
skeletal muscle organ development GO:0060538 78 0.010
small molecule catabolic process GO:0044282 3 0.010
regulation of nervous system development GO:0051960 90 0.010
sarcomere organization GO:0045214 26 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010

nexn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
Human
nervous system disease DOID:863 0 0.020
cardiovascular system disease DOID:1287 0 0.011
Human