Danio rerio

85 known processes

nf1a

neurofibromin 1a

(Aliases: si:dkey-15g19.1)

nf1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 85 0.899
Mouse
positive regulation of endothelial cell proliferation GO:0001938 1 0.891
Mouse
neuron neuron synaptic transmission GO:0007270 1 0.889
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.795
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.783
Mouse Fly
cognition GO:0050890 1 0.777
Mouse Fly
regulation of epithelial cell proliferation GO:0050678 3 0.769
Mouse
ribonucleotide biosynthetic process GO:0009260 20 0.764
Mouse Fly
nucleotide biosynthetic process GO:0009165 21 0.756
Mouse Fly
carbohydrate derivative biosynthetic process GO:1901137 43 0.724
Mouse Fly
nucleoside phosphate biosynthetic process GO:1901293 21 0.722
Mouse Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.717
Mouse
regulation of synapse assembly GO:0051963 3 0.715
Fly
locomotion GO:0040011 313 0.683
Mouse
regulation of cell matrix adhesion GO:0001952 1 0.682
Mouse
chemosensory behavior GO:0007635 1 0.681
Fly
signal transduction GO:0007165 455 0.677
regulation of cyclase activity GO:0031279 12 0.663
Mouse Fly
response to chemical GO:0042221 320 0.656
Fly
negative regulation of protein localization to nucleus GO:1900181 2 0.654
Mouse
regulation of synapse organization GO:0050807 3 0.647
Fly
ribose phosphate biosynthetic process GO:0046390 20 0.638
Mouse Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.638
Fly
endothelial cell proliferation GO:0001935 11 0.634
Mouse
cell substrate adhesion GO:0031589 4 0.622
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 5 0.614
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.612
Mouse
negative regulation of synapse assembly GO:0051964 2 0.612
Fly
phosphatidylinositol mediated signaling GO:0048015 2 0.609
Mouse
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.604
Mouse Fly
neuron differentiation GO:0030182 353 0.597
Rat
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.594
Mouse Fly
regulation of neurotransmitter transport GO:0051588 1 0.586
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.584
Mouse
positive regulation of camp biosynthetic process GO:0030819 2 0.581
Mouse Fly
urogenital system development GO:0001655 97 0.577
Mouse
oligodendrocyte differentiation GO:0048709 23 0.575
Mouse
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.559
Mouse Fly
cell migration GO:0016477 237 0.552
Mouse
erk1 and erk2 cascade GO:0070371 4 0.547
myelination GO:0042552 18 0.546
Mouse
cyclic nucleotide metabolic process GO:0009187 18 0.543
Mouse Fly
sensory organ development GO:0007423 393 0.530
Mouse
regulation of camp metabolic process GO:0030814 9 0.530
Mouse Fly
negative regulation of cytoplasmic transport GO:1903650 2 0.529
Mouse
system process GO:0003008 185 0.528
Mouse Fly
negative regulation of protein transport GO:0051224 3 0.514
Mouse
regulation of cell substrate adhesion GO:0010810 1 0.512
Mouse
protein localization to nucleus GO:0034504 3 0.507
Mouse
regulation of developmental process GO:0050793 247 0.507
brain development GO:0007420 293 0.507
Mouse
establishment of protein localization to organelle GO:0072594 4 0.505
Mouse
cell matrix adhesion GO:0007160 4 0.492
Mouse
hemopoiesis GO:0030097 183 0.481
Mouse
neurotransmitter secretion GO:0007269 2 0.481
Mouse
protein import GO:0017038 3 0.481
Mouse
multicellular organism growth GO:0035264 4 0.480
Fly
regulation of protein localization to nucleus GO:1900180 2 0.462
Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.460
Mouse Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.454
regulation of signal transduction GO:0009966 225 0.452
circadian rhythm GO:0007623 19 0.431
Fly
positive regulation of camp metabolic process GO:0030816 2 0.425
Mouse Fly
signal transduction in absence of ligand GO:0038034 1 0.417
Mouse
ossification GO:0001503 23 0.416
Mouse
brain morphogenesis GO:0048854 18 0.415
Mouse
regulation of establishment of protein localization GO:0070201 4 0.414
Mouse
negative regulation of secretion GO:0051048 2 0.404
Mouse
liver development GO:0001889 96 0.403
Mouse
locomotor rhythm GO:0045475 3 0.401
Fly
regulation of synaptic plasticity GO:0048167 1 0.400
Mouse
regulation of gtp catabolic process GO:0033124 2 0.398
Mouse Rat Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.396
Mouse
cell motility GO:0048870 244 0.382
Mouse
regulation of endothelial cell proliferation GO:0001936 1 0.382
Mouse
regulation of nucleotide biosynthetic process GO:0030808 15 0.380
Mouse Fly
nuclear transport GO:0051169 4 0.376
Mouse
immune system development GO:0002520 191 0.374
Mouse
regulation of protein transport GO:0051223 3 0.374
Mouse
hepaticobiliary system development GO:0061008 98 0.373
Mouse
regulation of signaling GO:0023051 235 0.368
negative regulation of ras protein signal transduction GO:0046580 1 0.367
Mouse
axon ensheathment GO:0008366 18 0.365
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.364
Mouse
regulation of cell development GO:0060284 100 0.361
gliogenesis GO:0042063 45 0.357
kidney development GO:0001822 92 0.356
Mouse
regulation of glial cell differentiation GO:0045685 4 0.351
blood vessel morphogenesis GO:0048514 216 0.348
Mouse
generation of neurons GO:0048699 385 0.344
central nervous system development GO:0007417 387 0.340
Mouse
regulation of stem cell proliferation GO:0072091 2 0.339
Mouse
protein import into nucleus GO:0006606 3 0.337
Mouse
cellular component morphogenesis GO:0032989 336 0.336
positive regulation of lyase activity GO:0051349 6 0.334
Mouse Fly
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.321
Mouse Fly
negative regulation of protein kinase activity GO:0006469 4 0.319
Mouse
head development GO:0060322 303 0.318
Mouse
regulation of membrane potential GO:0042391 23 0.313
Mouse
regulation of cell communication GO:0010646 232 0.311
negative regulation of protein import into nucleus GO:0042308 2 0.311
Mouse
cyclic nucleotide biosynthetic process GO:0009190 18 0.305
Mouse Fly
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.305
Mouse
regulation of protein import into nucleus GO:0042306 2 0.304
Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.302
Mouse
negative regulation of intracellular protein transport GO:0090317 3 0.302
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.301
Mouse Rat Fly
single organism nuclear import GO:1902593 3 0.301
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.301
Mouse Rat Fly
single organism transport GO:0044765 206 0.299
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.292
Mouse
positive regulation of gtpase activity GO:0043547 1 0.286
Mouse Fly
regulation of leukocyte differentiation GO:1902105 5 0.285
Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.278
Mouse Fly
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.278
Mouse
single organism localization GO:1902578 225 0.277
Mouse
heterocycle biosynthetic process GO:0018130 215 0.273
Mouse Fly
response to radiation GO:0009314 51 0.273
Mouse
regulation of neurotransmitter secretion GO:0046928 1 0.270
Mouse
response to light stimulus GO:0009416 46 0.267
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.266
Mouse Rat Fly
myeloid cell differentiation GO:0030099 86 0.264
Mouse
regulation of neurogenesis GO:0050767 87 0.260
organophosphate biosynthetic process GO:0090407 23 0.254
Mouse Fly
regulation of biological quality GO:0065008 263 0.254
Mouse Fly
regulation of myeloid cell differentiation GO:0045637 8 0.253
Mouse
negative regulation of signal transduction GO:0009968 94 0.252
cell death GO:0008219 121 0.250
Mouse
regulation of purine nucleotide metabolic process GO:1900542 17 0.247
Mouse Rat Fly
nuclear import GO:0051170 3 0.246
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.242
Mouse Fly
negative regulation of signaling GO:0023057 96 0.239
negative regulation of catalytic activity GO:0043086 21 0.237
Mouse
regulation of nervous system development GO:0051960 90 0.236
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.234
Mouse Fly
gland development GO:0048732 143 0.232
Mouse
osteoclast differentiation GO:0030316 1 0.229
Mouse
positive regulation of cyclase activity GO:0031281 6 0.229
Mouse Fly
spinal cord development GO:0021510 46 0.228
Mouse
leukocyte differentiation GO:0002521 25 0.225
Mouse
ensheathment of neurons GO:0007272 18 0.225
Mouse
vasculature development GO:0001944 278 0.225
intracellular signal transduction GO:0035556 85 0.223
synaptic transmission GO:0007268 35 0.221
Mouse Fly
positive regulation of neuron apoptotic process GO:0043525 1 0.220
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.220
Mouse Fly
rhythmic process GO:0048511 21 0.220
Fly
regulation of synapse structure and activity GO:0050803 5 0.219
Fly
chordate embryonic development GO:0043009 271 0.214
Mouse
gtp metabolic process GO:0046039 4 0.212
Mouse Rat Fly
osteoblast differentiation GO:0001649 5 0.212
Mouse
neural precursor cell proliferation GO:0061351 20 0.211
regulation of cellular component organization GO:0051128 86 0.210
Fly
positive regulation of cell communication GO:0010647 56 0.209
Mouse
negative regulation of leukocyte differentiation GO:1902106 1 0.209
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.208
Mouse
small molecule metabolic process GO:0044281 77 0.205
Mouse Rat Fly
neurotransmitter transport GO:0006836 2 0.203
Mouse
regulation of multicellular organismal development GO:2000026 223 0.203
cell projection organization GO:0030030 284 0.202
cellular component biogenesis GO:0044085 178 0.201
Fly
blood vessel development GO:0001568 246 0.201
regulation of anatomical structure morphogenesis GO:0022603 130 0.198
Mouse
regulation of neuronal synaptic plasticity GO:0048168 1 0.198
Mouse
response to heat GO:0009408 6 0.196
Fly
heart morphogenesis GO:0003007 156 0.193
single organism metabolic process GO:0044710 217 0.193
ras protein signal transduction GO:0007265 7 0.191
Mouse Fly
actin filament based process GO:0030029 64 0.190
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.190
Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.187
negative regulation of intracellular signal transduction GO:1902532 22 0.185
circadian behavior GO:0048512 5 0.185
Fly
negative regulation of intracellular transport GO:0032387 3 0.181
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.180
Mouse
nucleotide metabolic process GO:0009117 28 0.179
Mouse Rat Fly
organonitrogen compound metabolic process GO:1901564 74 0.179
Mouse Rat Fly
action potential GO:0001508 19 0.176
Mouse
negative regulation of cellular process GO:0048523 283 0.175
regulation of multicellular organism growth GO:0040014 4 0.175
Fly
negative regulation of developmental growth GO:0048640 9 0.174
Fly
transport GO:0006810 220 0.172
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.172
Mouse
neuron development GO:0048666 262 0.171
synapse assembly GO:0007416 9 0.171
Fly
death GO:0016265 121 0.168
Mouse
growth GO:0040007 174 0.168
Fly
angiogenesis GO:0001525 158 0.167
Mouse
response to hypoxia GO:0001666 25 0.166
Mouse
behavior GO:0007610 74 0.166
Mouse Fly
negative regulation of neural precursor cell proliferation GO:2000178 1 0.165
Mouse
response to temperature stimulus GO:0009266 15 0.164
Fly
cell morphogenesis GO:0000902 289 0.163
positive regulation of apoptotic process GO:0043065 29 0.161
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.160
Mouse Rat Fly
locomotory behavior GO:0007626 34 0.160
Fly
programmed cell death GO:0012501 119 0.159
Mouse
response to oxygen levels GO:0070482 25 0.159
Mouse
negative regulation of secretion by cell GO:1903531 2 0.159
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.158
cell adhesion GO:0007155 40 0.158
Mouse
camera type eye morphogenesis GO:0048593 108 0.157
Mouse
localization of cell GO:0051674 244 0.156
Mouse
cellular component movement GO:0006928 335 0.156
Mouse
regulation of apoptotic signaling pathway GO:2001233 12 0.154
Mouse
developmental growth GO:0048589 166 0.153
Fly
regulation of lyase activity GO:0051339 12 0.151
Mouse Fly
negative regulation of growth GO:0045926 10 0.150
Fly
negative regulation of cell adhesion GO:0007162 6 0.149
Mouse
forebrain development GO:0030900 96 0.146
Mouse
developmental pigmentation GO:0048066 48 0.146
glial cell proliferation GO:0014009 4 0.144
negative regulation of kinase activity GO:0033673 4 0.144
Mouse
cellular biosynthetic process GO:0044249 286 0.143
Mouse Fly
regulation of cell death GO:0010941 103 0.143
Mouse
cellular component assembly GO:0022607 170 0.143
Fly
negative regulation of tor signaling GO:0032007 2 0.142
muscle structure development GO:0061061 196 0.141
Mouse
wound healing GO:0042060 90 0.138
Mouse
regulation of homeostatic process GO:0032844 9 0.137
Mouse
adrenal gland development GO:0030325 10 0.137
Mouse
cytoskeleton organization GO:0007010 96 0.135
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.135
Mouse Fly
cell part morphogenesis GO:0032990 246 0.134
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.134
Fly
purine ribonucleotide metabolic process GO:0009150 27 0.132
Mouse Rat Fly
positive regulation of biological process GO:0048518 253 0.132
Mouse Fly
negative regulation of map kinase activity GO:0043407 2 0.132
Mouse
melanocyte differentiation GO:0030318 26 0.131
heart development GO:0007507 313 0.130
apoptotic signaling pathway GO:0097190 23 0.130
Mouse
anatomical structure homeostasis GO:0060249 36 0.126
Mouse
stem cell proliferation GO:0072089 4 0.126
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.124
cellular amine metabolic process GO:0044106 2 0.124
positive regulation of signaling GO:0023056 56 0.123
Mouse
establishment of localization GO:0051234 244 0.123
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.123
Mouse
negative regulation of mapk cascade GO:0043409 4 0.123
positive regulation of nucleoside metabolic process GO:0045979 1 0.122
Mouse Fly
regulation of apoptotic process GO:0042981 98 0.122
Mouse
artery development GO:0060840 22 0.122
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.121
small gtpase mediated signal transduction GO:0007264 8 0.120
Mouse Fly
circulatory system process GO:0003013 87 0.120
collagen fibril organization GO:0030199 1 0.118
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.115
Mouse Fly
pigment cell differentiation GO:0050931 38 0.111
cell cell signaling GO:0007267 52 0.111
Mouse Fly
larval development GO:0002164 2 0.111
nucleobase containing compound metabolic process GO:0006139 274 0.110
Mouse Rat Fly
actin cytoskeleton organization GO:0030036 63 0.108
Mouse
neuron projection guidance GO:0097485 86 0.106
taxis GO:0042330 109 0.106
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.104
Mouse
response to wounding GO:0009611 116 0.103
Mouse
regulation of oligodendrocyte differentiation GO:0048713 1 0.102
Mouse
single organism biosynthetic process GO:0044711 71 0.102
Mouse Fly
regulation of cell adhesion GO:0030155 15 0.101
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.100
Mouse Rat Fly
protein localization GO:0008104 40 0.098
Mouse
cellular response to growth factor stimulus GO:0071363 39 0.096
purine nucleotide metabolic process GO:0006163 27 0.095
Mouse Rat Fly
axon guidance GO:0007411 86 0.095
neuromuscular junction development GO:0007528 9 0.095
Fly
negative regulation of cell communication GO:0010648 96 0.094
positive regulation of programmed cell death GO:0043068 29 0.094
Mouse
negative regulation of myeloid cell differentiation GO:0045638 1 0.093
Mouse
embryonic organ development GO:0048568 381 0.093
visual behavior GO:0007632 10 0.093
Mouse
response to stress GO:0006950 263 0.092
Mouse Fly
response to abiotic stimulus GO:0009628 122 0.092
Mouse Fly
neural tube development GO:0021915 62 0.091
Mouse
homeostatic process GO:0042592 142 0.091
Mouse
extracellular matrix organization GO:0030198 27 0.090
Mouse
regulation of bone remodeling GO:0046850 2 0.090
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.089
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.088
Mouse Rat Fly
negative regulation of gliogenesis GO:0014014 1 0.087
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.087
Mouse Fly
multicellular organismal homeostasis GO:0048871 29 0.087
Mouse
positive regulation of cellular process GO:0048522 201 0.086
Mouse Fly
heterocycle metabolic process GO:0046483 290 0.086
Mouse Rat Fly
nitrogen compound metabolic process GO:0006807 319 0.086
Mouse Rat Fly
negative regulation of cellular component organization GO:0051129 16 0.086
Fly
regulation of autophagy GO:0010506 3 0.085
regulation of cellular component movement GO:0051270 55 0.081
Mouse
regulation of system process GO:0044057 40 0.081
regulation of hydrolase activity GO:0051336 28 0.081
Mouse Rat Fly
epithelial cell differentiation GO:0030855 116 0.081
catabolic process GO:0009056 32 0.081
Mouse Rat Fly
sympathetic nervous system development GO:0048485 3 0.080
Mouse
organelle organization GO:0006996 227 0.080
Mouse
regulation of blood vessel size GO:0050880 2 0.080
axon development GO:0061564 166 0.080
regulation of multicellular organismal process GO:0051239 277 0.080
negative regulation of cellular metabolic process GO:0031324 77 0.079
peripheral nervous system development GO:0007422 55 0.079
Mouse
cellular macromolecule localization GO:0070727 21 0.077
Mouse
regulation of cell differentiation GO:0045595 142 0.076
regulation of response to stimulus GO:0048583 269 0.075
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.074
Mouse
regulation of rac protein signal transduction GO:0035020 1 0.074
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.074
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.074
Mouse Fly
regulation of tube size GO:0035150 2 0.074
enzyme linked receptor protein signaling pathway GO:0007167 106 0.073
negative regulation of cell development GO:0010721 26 0.073
Mouse
schwann cell development GO:0014044 9 0.072
Mouse
organic substance transport GO:0071702 58 0.072
Mouse
positive regulation of cell death GO:0010942 29 0.071
Mouse
amine metabolic process GO:0009308 2 0.071
cell projection morphogenesis GO:0048858 244 0.070
regulation of cellular metabolic process GO:0031323 320 0.069
organic cyclic compound metabolic process GO:1901360 301 0.068
Mouse Rat Fly
artery morphogenesis GO:0048844 14 0.068
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.068
Mouse Fly
cellular protein metabolic process GO:0044267 129 0.067
Mouse
negative regulation of catabolic process GO:0009895 3 0.067
positive regulation of cellular component biogenesis GO:0044089 3 0.067
stem cell division GO:0017145 1 0.066
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.066
biosynthetic process GO:0009058 294 0.065
Mouse Fly
meiotic nuclear division GO:0007126 4 0.065
positive regulation of transport GO:0051050 2 0.065
macromolecule modification GO:0043412 111 0.064
Mouse
nucleoside phosphate metabolic process GO:0006753 28 0.064
Mouse Rat Fly
camera type eye development GO:0043010 222 0.064
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.064
regulation of locomotion GO:0040012 55 0.063
Mouse
positive regulation of myeloid cell differentiation GO:0045639 2 0.063
digestive tract development GO:0048565 265 0.063
negative regulation of locomotion GO:0040013 18 0.063
Mouse
negative regulation of cell motility GO:2000146 17 0.063
Mouse
negative regulation of biological process GO:0048519 304 0.063
neuron apoptotic process GO:0051402 20 0.063
Mouse
regulation of localization GO:0032879 104 0.062
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.062
Mouse Fly
negative regulation of angiogenesis GO:0016525 7 0.061
Mouse
aging GO:0007568 2 0.060
Fly
digestive system development GO:0055123 289 0.060
positive regulation of map kinase activity GO:0043406 3 0.060
regulation of cellular response to growth factor stimulus GO:0090287 35 0.059
negative regulation of nervous system development GO:0051961 22 0.059
Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.058
gene expression GO:0010467 252 0.058
negative regulation of neurogenesis GO:0050768 20 0.058
Mouse
cellular ketone metabolic process GO:0042180 11 0.058
regulation of cell shape GO:0008360 1 0.058
nucleic acid metabolic process GO:0090304 244 0.057
embryonic heart tube development GO:0035050 133 0.057
positive regulation of hydrolase activity GO:0051345 13 0.056
Mouse Fly
axonogenesis GO:0007409 152 0.056
striated muscle tissue development GO:0014706 110 0.056
Mouse
positive regulation of response to stimulus GO:0048584 80 0.056
Mouse
response to organic substance GO:0010033 153 0.056
regulation of cell growth GO:0001558 29 0.056
apoptotic process GO:0006915 116 0.056
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.056
Mouse Rat Fly
negative regulation of cellular protein metabolic process GO:0032269 16 0.056
Mouse
positive regulation of cell proliferation GO:0008284 15 0.055
Mouse
negative regulation of response to stimulus GO:0048585 104 0.055
autophagy GO:0006914 4 0.054
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
Mouse Rat Fly
regulation of mapk cascade GO:0043408 14 0.054
organic cyclic compound biosynthetic process GO:1901362 223 0.054
Mouse Fly
single organism behavior GO:0044708 24 0.053
Mouse Fly
single organism organelle organization GO:1902589 199 0.053
Mouse
regulation of cellular component size GO:0032535 30 0.053
schwann cell differentiation GO:0014037 9 0.053
Mouse
hypothalamus cell differentiation GO:0021979 4 0.053
skeletal muscle organ development GO:0060538 78 0.052
Mouse
positive regulation of nucleotide metabolic process GO:0045981 9 0.052
Mouse Fly
smooth muscle tissue development GO:0048745 1 0.051
Mouse
regulation of immune system process GO:0002682 34 0.051
Mouse
reflex GO:0060004 2 0.051
organophosphate metabolic process GO:0019637 37 0.050
Mouse Rat Fly
ameboidal type cell migration GO:0001667 143 0.050
regulation of axonogenesis GO:0050770 32 0.050
cell projection assembly GO:0030031 64 0.050
protein modification process GO:0036211 100 0.050
Mouse
ribose phosphate metabolic process GO:0019693 27 0.050
Mouse Rat Fly
regulation of biosynthetic process GO:0009889 250 0.049
Mouse Fly
stem cell maintenance GO:0019827 4 0.049
regulation of cell projection organization GO:0031344 44 0.049
organic substance biosynthetic process GO:1901576 289 0.048
Mouse Fly
chemotaxis GO:0006935 104 0.048
signal transduction by phosphorylation GO:0023014 18 0.048
positive regulation of developmental process GO:0051094 50 0.048
Fly
negative regulation of programmed cell death GO:0043069 58 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.047
regulation of vasculature development GO:1901342 33 0.047
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.047
regulation of cysteine type endopeptidase activity GO:2000116 21 0.047
reproductive process GO:0022414 40 0.047
homeostasis of number of cells GO:0048872 62 0.046
regulation of neuron apoptotic process GO:0043523 17 0.046
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.045
neurological system process GO:0050877 62 0.045
Mouse Fly
cellular response to starvation GO:0009267 1 0.045
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.044
cellular amino acid metabolic process GO:0006520 7 0.044
neuron projection development GO:0031175 180 0.044
cellular catabolic process GO:0044248 27 0.044
Mouse Rat Fly
tube morphogenesis GO:0035239 349 0.044
negative regulation of cell migration GO:0030336 17 0.044
Mouse
regulation of growth GO:0040008 42 0.044
Fly
regulation of angiogenesis GO:0045765 26 0.044
Mouse
homeostasis of number of cells within a tissue GO:0048873 4 0.042
cell cycle g1 s phase transition GO:0044843 1 0.042
regulation of glial cell proliferation GO:0060251 4 0.042
regulation of cell morphogenesis GO:0022604 42 0.042
regulation of molecular function GO:0065009 70 0.042
Mouse Rat Fly
myelination in peripheral nervous system GO:0022011 4 0.042
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.041
dicarboxylic acid transport GO:0006835 1 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
Mouse Rat Fly
positive regulation of metabolic process GO:0009893 108 0.041
Mouse Fly
phosphorylation GO:0016310 69 0.041
cellular protein modification process GO:0006464 100 0.041
Mouse
negative regulation of peptidase activity GO:0010466 10 0.041
cellular carbohydrate metabolic process GO:0044262 4 0.039
cell cycle process GO:0022402 53 0.039
response to endogenous stimulus GO:0009719 83 0.039
single organism cellular localization GO:1902580 46 0.038
Mouse
smooth muscle contraction GO:0006939 2 0.038
negative regulation of metabolic process GO:0009892 86 0.037
g1 s transition of mitotic cell cycle GO:0000082 1 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.037
Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
Mouse
multi organism cellular process GO:0044764 2 0.037
regulation of phosphorylation GO:0042325 26 0.037
cell growth GO:0016049 57 0.036
Fly
positive regulation of molecular function GO:0044093 33 0.036
Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.036
Mouse Rat Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
response to external stimulus GO:0009605 264 0.035
regulation of gene expression GO:0010468 265 0.035
positive regulation of cellular biosynthetic process GO:0031328 68 0.035
Mouse Fly
skeletal muscle tissue development GO:0007519 67 0.035
Mouse
positive regulation of positive chemotaxis GO:0050927 4 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
regulation of phosphorus metabolic process GO:0051174 43 0.035
cell fate commitment GO:0045165 99 0.034
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.034
Mouse
regulation of cell activation GO:0050865 1 0.034
regulation of kinase activity GO:0043549 15 0.034
Mouse
neuron projection morphogenesis GO:0048812 161 0.033
protein secretion GO:0009306 1 0.033
regulation of cell size GO:0008361 29 0.033
positive regulation of secretion GO:0051047 1 0.032
negative regulation of cellular component movement GO:0051271 18 0.032
Mouse
epithelium migration GO:0090132 25 0.032
phosphorus metabolic process GO:0006793 109 0.032
positive regulation of cell cycle GO:0045787 3 0.032
regulation of transport GO:0051049 45 0.032
Mouse
cell proliferation GO:0008283 80 0.032
exocytosis GO:0006887 1 0.032
eye morphogenesis GO:0048592 144 0.032
Mouse
renal system development GO:0072001 94 0.031
Mouse
transmission of nerve impulse GO:0019226 19 0.031
Mouse
neuron projection extension GO:1990138 45 0.031
cation transmembrane transport GO:0098655 65 0.031
regulation of cytokine production GO:0001817 3 0.031
nucleobase containing compound catabolic process GO:0034655 15 0.031
Mouse Rat Fly
reproduction GO:0000003 40 0.031
cilium organization GO:0044782 71 0.031
positive regulation of catalytic activity GO:0043085 25 0.031
Mouse Fly
negative regulation of developmental process GO:0051093 65 0.031
Mouse Fly
cellular response to oxygen levels GO:0071453 1 0.030
somatic stem cell maintenance GO:0035019 1 0.030
cellular response to external stimulus GO:0071496 2 0.030
macromolecule localization GO:0033036 54 0.030
Mouse
organic substance catabolic process GO:1901575 28 0.030
Mouse Rat Fly
regulation of blood pressure GO:0008217 1 0.030
regulation of map kinase activity GO:0043405 5 0.029
Mouse
protein acylation GO:0043543 3 0.029
cellular response to nutrient levels GO:0031669 2 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
tissue homeostasis GO:0001894 25 0.029
Mouse
positive regulation of phosphorus metabolic process GO:0010562 21 0.029
Mouse Fly
neuroblast proliferation GO:0007405 2 0.029
Mouse
skeletal system development GO:0001501 181 0.029
cell substrate junction assembly GO:0007044 2 0.029
commissural neuron axon guidance GO:0071679 3 0.029
glial cell differentiation GO:0010001 42 0.029
organic acid metabolic process GO:0006082 31 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
Mouse
response to growth factor GO:0070848 39 0.028
regulation of mesenchymal cell proliferation GO:0010464 1 0.028
positive regulation of biosynthetic process GO:0009891 68 0.028
Mouse Fly
cilium morphogenesis GO:0060271 85 0.028
rna biosynthetic process GO:0032774 181 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028

nf1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.090
cardiovascular system disease DOID:1287 0 0.037