Danio rerio

85 known processes

nf1b

neurofibromin 1b

(Aliases: fe06d03,wu:fe06d03,nf1,hm:zehn0874)

nf1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of endothelial cell proliferation GO:0001938 1 0.530
Mouse
blood vessel development GO:0001568 246 0.523
stem cell proliferation GO:0072089 4 0.410
Mouse
regulation of stem cell proliferation GO:0072091 2 0.408
Mouse
positive regulation of camp metabolic process GO:0030816 2 0.375
Mouse Fly
cognition GO:0050890 1 0.352
Mouse Fly
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.351
Mouse Fly
chordate embryonic development GO:0043009 271 0.342
Mouse
regulation of metabolic process GO:0019222 359 0.337
positive regulation of camp biosynthetic process GO:0030819 2 0.326
Mouse Fly
regulation of endothelial cell proliferation GO:0001936 1 0.314
Mouse
artery development GO:0060840 22 0.314
Mouse
regulation of camp metabolic process GO:0030814 9 0.311
Mouse Fly
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.290
Mouse Fly
regulation of synaptic plasticity GO:0048167 1 0.286
Mouse
cellular component morphogenesis GO:0032989 336 0.279
regulation of lyase activity GO:0051339 12 0.270
Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.259
Mouse Fly
heterocycle metabolic process GO:0046483 290 0.258
Mouse Rat Fly
regulation of epithelial cell proliferation GO:0050678 3 0.253
Mouse
regulation of rac protein signal transduction GO:0035020 1 0.249
Mouse
regulation of biosynthetic process GO:0009889 250 0.246
Mouse Fly
vasculature development GO:0001944 278 0.244
aging GO:0007568 2 0.240
Fly
neurotransmitter secretion GO:0007269 2 0.236
Mouse
neuron neuron synaptic transmission GO:0007270 1 0.235
Mouse
signal transduction GO:0007165 455 0.232
nucleoside phosphate biosynthetic process GO:1901293 21 0.231
Mouse Fly
positive regulation of cellular process GO:0048522 201 0.228
Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.228
Mouse
protein import into nucleus GO:0006606 3 0.220
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.218
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.217
Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.215
Mouse Rat Fly
chemosensory behavior GO:0007635 1 0.215
Fly
regulation of neuronal synaptic plasticity GO:0048168 1 0.211
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.210
Mouse Fly
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.208
Mouse Fly
neurotransmitter transport GO:0006836 2 0.208
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.207
Mouse
camera type eye development GO:0043010 222 0.205
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.199
Mouse Rat Fly
artery morphogenesis GO:0048844 14 0.199
Mouse
regulation of response to stimulus GO:0048583 269 0.199
angiogenesis GO:0001525 158 0.197
Mouse
organelle organization GO:0006996 227 0.195
Mouse
response to stress GO:0006950 263 0.193
Mouse Fly
negative regulation of protein phosphorylation GO:0001933 4 0.192
Mouse
nitrogen compound metabolic process GO:0006807 319 0.190
Mouse Rat Fly
regulation of protein import into nucleus GO:0042306 2 0.190
Mouse
regulation of protein transport GO:0051223 3 0.190
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.183
Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.179
Mouse Rat Fly
striated muscle tissue development GO:0014706 110 0.178
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.178
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.175
Mouse Rat Fly
regulation of synapse organization GO:0050807 3 0.173
Fly
regulation of cellular metabolic process GO:0031323 320 0.171
ribose phosphate biosynthetic process GO:0046390 20 0.168
Mouse Fly
regulation of protein localization to nucleus GO:1900180 2 0.167
Mouse
system process GO:0003008 185 0.164
Mouse Fly
cell surface receptor signaling pathway GO:0007166 325 0.161
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.161
Mouse Fly
regulation of establishment of protein localization GO:0070201 4 0.161
Mouse
negative regulation of biological process GO:0048519 304 0.159
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.155
Mouse
negative regulation of neural precursor cell proliferation GO:2000178 1 0.155
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.155
Mouse Rat Fly
single organism transport GO:0044765 206 0.154
Mouse
ribonucleotide biosynthetic process GO:0009260 20 0.153
Mouse Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.151
Mouse
sensory organ development GO:0007423 393 0.150
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.150
Mouse Fly
response to chemical GO:0042221 320 0.150
Fly
positive regulation of transport GO:0051050 2 0.150
establishment of localization GO:0051234 244 0.148
Mouse
single organism nuclear import GO:1902593 3 0.147
Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.147
Mouse Fly
cyclic nucleotide biosynthetic process GO:0009190 18 0.145
Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.145
Mouse Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.141
Mouse
nuclear import GO:0051170 3 0.140
Mouse
negative regulation of map kinase activity GO:0043407 2 0.139
Mouse
positive regulation of biological process GO:0048518 253 0.139
Mouse Fly
skeletal muscle organ development GO:0060538 78 0.138
Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.135
Mouse
biosynthetic process GO:0009058 294 0.135
Mouse Fly
regulation of nucleotide biosynthetic process GO:0030808 15 0.134
Mouse Fly
cyclic nucleotide metabolic process GO:0009187 18 0.134
Mouse Fly
regulation of cell substrate adhesion GO:0010810 1 0.133
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.132
Mouse Rat Fly
cellular component assembly GO:0022607 170 0.132
Fly
negative regulation of protein localization to nucleus GO:1900181 2 0.132
Mouse
gene expression GO:0010467 252 0.131
immune system development GO:0002520 191 0.129
Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.128
Mouse Fly
regulation of cyclase activity GO:0031279 12 0.128
Mouse Fly
single organism localization GO:1902578 225 0.127
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.127
Mouse Rat Fly
regulation of biological quality GO:0065008 263 0.125
Mouse Fly
guanosine containing compound catabolic process GO:1901069 2 0.125
Mouse Rat Fly
nuclear transport GO:0051169 4 0.123
Mouse
negative regulation of protein transport GO:0051224 3 0.122
Mouse
negative regulation of secretion GO:0051048 2 0.121
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.121
Mouse
cellular biosynthetic process GO:0044249 286 0.120
Mouse Fly
nucleotide biosynthetic process GO:0009165 21 0.119
Mouse Fly
cell substrate adhesion GO:0031589 4 0.118
Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.117
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.116
Mouse Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.116
Mouse Fly
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.116
Mouse
multicellular organism growth GO:0035264 4 0.116
Fly
protein localization to nucleus GO:0034504 3 0.115
Mouse
regulation of signal transduction GO:0009966 225 0.114
regulation of cell communication GO:0010646 232 0.113
response to oxygen levels GO:0070482 25 0.113
Mouse
regulation of localization GO:0032879 104 0.111
Mouse
regulation of gtp catabolic process GO:0033124 2 0.110
Mouse Rat Fly
cell morphogenesis GO:0000902 289 0.108
regulation of cell matrix adhesion GO:0001952 1 0.107
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.105
Mouse Fly
cell matrix adhesion GO:0007160 4 0.105
Mouse
establishment of localization in cell GO:0051649 77 0.105
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.104
Mouse Fly
single organism organelle organization GO:1902589 199 0.104
Mouse
regulation of synapse assembly GO:0051963 3 0.104
Fly
larval development GO:0002164 2 0.104
gtp metabolic process GO:0046039 4 0.103
Mouse Rat Fly
establishment of protein localization to organelle GO:0072594 4 0.103
Mouse
regulation of developmental process GO:0050793 247 0.103
negative regulation of cytoplasmic transport GO:1903650 2 0.102
Mouse
single organism biosynthetic process GO:0044711 71 0.102
Mouse Fly
hemopoiesis GO:0030097 183 0.101
Mouse
negative regulation of kinase activity GO:0033673 4 0.101
Mouse
negative regulation of cellular process GO:0048523 283 0.101
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.100
Mouse Rat Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.100
regulation of erk1 and erk2 cascade GO:0070372 4 0.099
locomotion GO:0040011 313 0.098
Mouse
positive regulation of neuron apoptotic process GO:0043525 1 0.098
Mouse
sympathetic nervous system development GO:0048485 3 0.098
Mouse
positive regulation of metabolic process GO:0009893 108 0.098
Mouse Fly
regulation of cytoplasmic transport GO:1903649 4 0.097
Mouse
positive regulation of cyclase activity GO:0031281 6 0.097
Mouse Fly
regulation of cellular response to growth factor stimulus GO:0090287 35 0.097
cell migration GO:0016477 237 0.095
Mouse
developmental growth GO:0048589 166 0.095
Fly
regulation of primary metabolic process GO:0080090 311 0.094
Mouse Rat Fly
negative regulation of gliogenesis GO:0014014 1 0.093
Mouse
regulation of signaling GO:0023051 235 0.093
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.092
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.092
Mouse
somite development GO:0061053 96 0.091
response to external stimulus GO:0009605 264 0.091
negative regulation of secretion by cell GO:1903531 2 0.089
Mouse
forebrain development GO:0030900 96 0.089
Mouse
heart development GO:0007507 313 0.088
regulation of multicellular organismal process GO:0051239 277 0.087
regulation of multicellular organism growth GO:0040014 4 0.086
Fly
response to abiotic stimulus GO:0009628 122 0.086
Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.085
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.084
Mouse Fly
cellular component movement GO:0006928 335 0.083
Mouse
erk1 and erk2 cascade GO:0070371 4 0.083
protein import GO:0017038 3 0.083
Mouse
negative regulation of synapse assembly GO:0051964 2 0.081
Fly
cell motility GO:0048870 244 0.081
Mouse
head development GO:0060322 303 0.079
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.079
Mouse Fly
negative regulation of ras protein signal transduction GO:0046580 1 0.079
Mouse
glial cell proliferation GO:0014009 4 0.079
ameboidal type cell migration GO:0001667 143 0.078
locomotor rhythm GO:0045475 3 0.078
Fly
regulation of apoptotic process GO:0042981 98 0.078
Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.078
Mouse
rna biosynthetic process GO:0032774 181 0.077
synaptic growth at neuromuscular junction GO:0051124 2 0.077
Fly
endothelial cell proliferation GO:0001935 11 0.077
Mouse
organophosphate biosynthetic process GO:0090407 23 0.077
Mouse Fly
regulation of neurotransmitter secretion GO:0046928 1 0.077
Mouse
transport GO:0006810 220 0.077
Mouse
spinal cord development GO:0021510 46 0.076
Mouse
positive regulation of gtpase activity GO:0043547 1 0.076
Mouse Fly
pigmentation GO:0043473 85 0.075
Mouse
osteoclast differentiation GO:0030316 1 0.075
Mouse
epithelial cell differentiation GO:0030855 116 0.074
cell projection morphogenesis GO:0048858 244 0.074
regulation of neurotransmitter transport GO:0051588 1 0.074
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.074
Mouse
regulation of multicellular organismal development GO:2000026 223 0.073
negative regulation of intracellular protein transport GO:0090317 3 0.072
Mouse
hepaticobiliary system development GO:0061008 98 0.072
Mouse
neural precursor cell proliferation GO:0061351 20 0.071
cellular component biogenesis GO:0044085 178 0.071
Fly
death GO:0016265 121 0.070
Mouse
central nervous system development GO:0007417 387 0.070
Mouse
cellular protein modification process GO:0006464 100 0.069
Mouse
regulation of gene expression GO:0010468 265 0.069
muscle organ development GO:0007517 101 0.069
Mouse
cellular ketone metabolic process GO:0042180 11 0.068
nucleic acid metabolic process GO:0090304 244 0.068
positive regulation of nucleoside metabolic process GO:0045979 1 0.068
Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.067
Mouse
neuron differentiation GO:0030182 353 0.067
Rat
amino acid transport GO:0006865 2 0.067
carbohydrate derivative biosynthetic process GO:1901137 43 0.067
Mouse Fly
brain morphogenesis GO:0048854 18 0.067
Mouse
transcription dna templated GO:0006351 181 0.066
rna metabolic process GO:0016070 219 0.066
skeletal muscle tissue development GO:0007519 67 0.066
Mouse
heart morphogenesis GO:0003007 156 0.065
regulation of blood vessel size GO:0050880 2 0.065
positive regulation of lyase activity GO:0051349 6 0.065
Mouse Fly
growth GO:0040007 174 0.065
Fly
gland development GO:0048732 143 0.064
Mouse
positive regulation of cell cycle GO:0045787 3 0.064
ras protein signal transduction GO:0007265 7 0.064
Mouse Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.063
Mouse
negative regulation of mapk cascade GO:0043409 4 0.063
localization of cell GO:0051674 244 0.063
Mouse
brain development GO:0007420 293 0.062
Mouse
camera type eye morphogenesis GO:0048593 108 0.062
Mouse
regulation of tube size GO:0035150 2 0.061
protein modification process GO:0036211 100 0.061
Mouse
regulation of glial cell differentiation GO:0045685 4 0.061
positive regulation of nucleotide catabolic process GO:0030813 1 0.061
Mouse Fly
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.061
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.061
Mouse Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.060
positive regulation of secretion by cell GO:1903532 1 0.060
neuroblast proliferation GO:0007405 2 0.060
Mouse
organic substance transport GO:0071702 58 0.060
Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.059
dicarboxylic acid transport GO:0006835 1 0.058
behavior GO:0007610 74 0.058
Mouse Fly
phosphate containing compound metabolic process GO:0006796 108 0.057
macromolecule modification GO:0043412 111 0.057
Mouse
response to radiation GO:0009314 51 0.056
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.056
Mouse Rat Fly
cell death GO:0008219 121 0.056
Mouse
generation of neurons GO:0048699 385 0.056
regulation of molecular function GO:0065009 70 0.055
Mouse Rat Fly
somitogenesis GO:0001756 87 0.055
anatomical structure homeostasis GO:0060249 36 0.055
Mouse
negative regulation of myeloid cell differentiation GO:0045638 1 0.054
Mouse
single organism metabolic process GO:0044710 217 0.053
regulation of cellular ketone metabolic process GO:0010565 7 0.053
regulation of cell death GO:0010941 103 0.053
Mouse
intracellular signal transduction GO:0035556 85 0.053
leukocyte differentiation GO:0002521 25 0.053
Mouse
muscle structure development GO:0061061 196 0.052
Mouse
ribose phosphate metabolic process GO:0019693 27 0.052
Mouse Rat Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.052
negative regulation of leukocyte differentiation GO:1902106 1 0.052
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.052
Mouse
apoptotic process GO:0006915 116 0.052
Mouse
nucleic acid templated transcription GO:0097659 181 0.052
negative regulation of protein import into nucleus GO:0042308 2 0.051
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.051
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
programmed cell death GO:0012501 119 0.050
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.050
Mouse
homeostatic process GO:0042592 142 0.050
Mouse
phosphatidylinositol mediated signaling GO:0048015 2 0.050
Mouse
amine metabolic process GO:0009308 2 0.050
actin cytoskeleton organization GO:0030036 63 0.050
Mouse
negative regulation of cell communication GO:0010648 96 0.050
collagen fibril organization GO:0030199 1 0.050
Mouse
cell projection assembly GO:0030031 64 0.049
phagocytosis GO:0006909 3 0.049
response to wounding GO:0009611 116 0.049
Mouse
stem cell division GO:0017145 1 0.049
macromolecule biosynthetic process GO:0009059 227 0.048
negative regulation of phosphate metabolic process GO:0045936 13 0.048
positive regulation of biosynthetic process GO:0009891 68 0.048
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.048
dopaminergic neuron differentiation GO:0071542 14 0.047
cellular protein catabolic process GO:0044257 4 0.047
actin filament based process GO:0030029 64 0.047
Mouse
myeloid cell differentiation GO:0030099 86 0.047
Mouse
proteasomal protein catabolic process GO:0010498 2 0.047
tube morphogenesis GO:0035239 349 0.047
regulation of transcription dna templated GO:0006355 213 0.047
oligodendrocyte differentiation GO:0048709 23 0.047
Mouse
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.046
Mouse
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.046
Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.046
small molecule metabolic process GO:0044281 77 0.046
Mouse Rat Fly
kidney development GO:0001822 92 0.046
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.045
Mouse Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.045
Fly
adrenal gland development GO:0030325 10 0.045
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.045
Mouse Rat Fly
nucleocytoplasmic transport GO:0006913 4 0.045
Mouse
negative regulation of intracellular transport GO:0032387 3 0.045
Mouse
regulation of protein targeting GO:1903533 2 0.045
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.045
Mouse Fly
phosphorylation GO:0016310 69 0.044
regionalization GO:0003002 274 0.044
positive regulation of cell communication GO:0010647 56 0.044
Mouse
positive regulation of map kinase activity GO:0043406 3 0.044
regulation of inflammatory response GO:0050727 2 0.044
maintenance of location GO:0051235 4 0.044
organonitrogen compound biosynthetic process GO:1901566 47 0.044
Mouse Fly
macromolecular complex subunit organization GO:0043933 74 0.044
Mouse
meiotic nuclear division GO:0007126 4 0.044
response to hypoxia GO:0001666 25 0.043
Mouse
cellular amine metabolic process GO:0044106 2 0.043
peptidyl serine phosphorylation GO:0018105 1 0.043
signal transduction in absence of ligand GO:0038034 1 0.043
Mouse
multi organism process GO:0051704 134 0.043
protein phosphorylation GO:0006468 47 0.043
Mouse
embryonic organ development GO:0048568 381 0.043
regulation of cell differentiation GO:0045595 142 0.043
negative regulation of signaling GO:0023057 96 0.043
liver development GO:0001889 96 0.043
Mouse
response to organic substance GO:0010033 153 0.043
eye morphogenesis GO:0048592 144 0.042
Mouse
g protein coupled receptor signaling pathway GO:0007186 74 0.042
regulation of cell morphogenesis GO:0022604 42 0.042
negative regulation of response to stimulus GO:0048585 104 0.042
positive regulation of signaling GO:0023056 56 0.042
Mouse
regulation of rna metabolic process GO:0051252 224 0.042
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.042
regulation of vasculature development GO:1901342 33 0.041
Mouse
small gtpase mediated signal transduction GO:0007264 8 0.041
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.040
cellular protein metabolic process GO:0044267 129 0.040
Mouse
regulation of cell shape GO:0008360 1 0.040
lymph vessel development GO:0001945 27 0.039
organic acid metabolic process GO:0006082 31 0.039
modification dependent protein catabolic process GO:0019941 3 0.039
positive regulation of stem cell proliferation GO:2000648 1 0.039
cellular amino acid metabolic process GO:0006520 7 0.039
neurological system process GO:0050877 62 0.038
Mouse Fly
negative regulation of signal transduction GO:0009968 94 0.038
response to drug GO:0042493 3 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
regulation of rna biosynthetic process GO:2001141 213 0.038
stem cell maintenance GO:0019827 4 0.038
regulation of immune system process GO:0002682 34 0.038
Mouse
cell part morphogenesis GO:0032990 246 0.037
muscle tissue development GO:0060537 110 0.037
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.037
protein secretion GO:0009306 1 0.037
response to light stimulus GO:0009416 46 0.037
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.037
multicellular organismal homeostasis GO:0048871 29 0.037
Mouse
regulation of muscle contraction GO:0006937 3 0.036
urogenital system development GO:0001655 97 0.036
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.036
single organism cellular localization GO:1902580 46 0.036
Mouse
regulation of cell migration GO:0030334 40 0.036
Mouse
cellular response to oxygen levels GO:0071453 1 0.036
cellular response to chemical stimulus GO:0070887 157 0.036
regulation of catalytic activity GO:0050790 55 0.036
Mouse Rat Fly
negative regulation of catabolic process GO:0009895 3 0.036
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.035
purine nucleotide metabolic process GO:0006163 27 0.035
Mouse Rat Fly
immune system process GO:0002376 241 0.035
Mouse
digestive system development GO:0055123 289 0.035
cell proliferation GO:0008283 80 0.034
neuron development GO:0048666 262 0.034
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.034
Mouse
regulation of cytokine production GO:0001817 3 0.034
eye development GO:0001654 277 0.034
Mouse
protein targeting to nucleus GO:0044744 3 0.034
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
regulation of glial cell proliferation GO:0060251 4 0.033
cellular response to external stimulus GO:0071496 2 0.033
hypothalamus cell differentiation GO:0021979 4 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.033
synaptic vesicle localization GO:0097479 1 0.033
response to biotic stimulus GO:0009607 97 0.033
segmentation GO:0035282 97 0.033
smooth muscle tissue development GO:0048745 1 0.032
Mouse
smooth muscle contraction GO:0006939 2 0.032
transcription from rna polymerase ii promoter GO:0006366 80 0.032
positive regulation of molecular function GO:0044093 33 0.032
Mouse Fly
regulation of blood pressure GO:0008217 1 0.032
response to external biotic stimulus GO:0043207 97 0.032
positive regulation of catalytic activity GO:0043085 25 0.032
Mouse Fly
visual behavior GO:0007632 10 0.031
Mouse
regulation of mesenchymal cell proliferation GO:0010464 1 0.031
sensory perception of chemical stimulus GO:0007606 3 0.031
macromolecule localization GO:0033036 54 0.031
Mouse
chemotaxis GO:0006935 104 0.031
regulation of autophagy GO:0010506 3 0.031
cytoskeleton organization GO:0007010 96 0.031
Mouse
exocytosis GO:0006887 1 0.031
regulation of protein complex assembly GO:0043254 3 0.031
regulation of locomotion GO:0040012 55 0.030
Mouse
positive regulation of cell proliferation GO:0008284 15 0.030
Mouse
regulation of hydrolase activity GO:0051336 28 0.030
Mouse Rat Fly
negative regulation of metabolic process GO:0009892 86 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
embryonic heart tube development GO:0035050 133 0.030
defense response GO:0006952 47 0.029
tissue homeostasis GO:0001894 25 0.029
Mouse
sprouting angiogenesis GO:0002040 53 0.029
regulation of nervous system development GO:0051960 90 0.029
oxoacid metabolic process GO:0043436 31 0.029
lipid storage GO:0019915 1 0.029
regulation of intracellular protein transport GO:0033157 3 0.029
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.029
Mouse
response to other organism GO:0051707 97 0.029
carboxylic acid metabolic process GO:0019752 22 0.029
determination of left right symmetry GO:0007368 179 0.029
protein acetylation GO:0006473 2 0.029
regulation of bone remodeling GO:0046850 2 0.028
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
synaptic transmission GO:0007268 35 0.028
Mouse Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.028
secondary metabolic process GO:0019748 3 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
positive regulation of hydrolase activity GO:0051345 13 0.028
Mouse Fly
cell projection organization GO:0030030 284 0.028
positive regulation of gene expression GO:0010628 71 0.028
cell cycle g1 s phase transition GO:0044843 1 0.028
response to temperature stimulus GO:0009266 15 0.028
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.028
negative regulation of angiogenesis GO:0016525 7 0.028
Mouse
intracellular transport GO:0046907 32 0.028
Mouse
regulation of oligodendrocyte differentiation GO:0048713 1 0.027
Mouse
anterior posterior pattern specification GO:0009952 152 0.027
wound healing GO:0042060 90 0.027
Mouse
regulation of purine nucleotide metabolic process GO:1900542 17 0.027
Mouse Rat Fly
hormone transport GO:0009914 2 0.027
organelle assembly GO:0070925 110 0.027
adherens junction organization GO:0034332 4 0.027
digestive tract morphogenesis GO:0048546 231 0.027
peptidyl lysine acetylation GO:0018394 2 0.027
development of primary female sexual characteristics GO:0046545 4 0.027
protein metabolic process GO:0019538 183 0.027
Mouse
cytokinesis GO:0000910 3 0.027
positive regulation of secretion GO:0051047 1 0.027
positive regulation of developmental process GO:0051094 50 0.027
Fly
mitochondrion organization GO:0007005 4 0.026
peptidyl serine modification GO:0018209 2 0.026
cilium morphogenesis GO:0060271 85 0.026
positive regulation of catabolic process GO:0009896 4 0.026
Mouse Fly
regulation of transport GO:0051049 45 0.026
Mouse
cytoplasm organization GO:0007028 4 0.026
regulation of intracellular signal transduction GO:1902531 57 0.026
regulation of cellular component movement GO:0051270 55 0.026
Mouse
female gonad development GO:0008585 4 0.026
cell morphogenesis involved in differentiation GO:0000904 195 0.026
circulatory system process GO:0003013 87 0.026
protein localization to plasma membrane GO:0072659 1 0.026
cellular response to hypoxia GO:0071456 1 0.025
female sex differentiation GO:0046660 4 0.025
regulation of cell development GO:0060284 100 0.025
mesenchyme development GO:0060485 127 0.025
negative regulation of developmental process GO:0051093 65 0.025
Mouse Fly
autophagy GO:0006914 4 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
Mouse Rat Fly
regulation of protein catabolic process GO:0042176 1 0.025
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
synaptic vesicle transport GO:0048489 1 0.024
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.024
regulation of myeloid leukocyte differentiation GO:0002761 5 0.024
Mouse
regulation of angiogenesis GO:0045765 26 0.024
Mouse
regulation of reproductive process GO:2000241 4 0.024
regulation of phosphate metabolic process GO:0019220 43 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
mesoderm development GO:0007498 88 0.024
startle response GO:0001964 4 0.023
muscle cell differentiation GO:0042692 139 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.023
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
Mouse
striated muscle cell differentiation GO:0051146 129 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
Mouse
regulation of cell activation GO:0050865 1 0.023
negative regulation of defense response GO:0031348 2 0.023
cell fate commitment GO:0045165 99 0.023
regulation of dendrite morphogenesis GO:0048814 3 0.022
renal system development GO:0072001 94 0.022
Mouse
regulation of dendrite development GO:0050773 3 0.022
cellular response to decreased oxygen levels GO:0036294 1 0.022
hormone secretion GO:0046879 2 0.022
nucleoside phosphate metabolic process GO:0006753 28 0.022
Mouse Rat Fly
purine ribonucleotide metabolic process GO:0009150 27 0.022
Mouse Rat Fly
locomotory behavior GO:0007626 34 0.022
Fly
cyclic purine nucleotide metabolic process GO:0052652 18 0.022
Mouse Fly
rhythmic process GO:0048511 21 0.022
Fly
protein acylation GO:0043543 3 0.022
cellular response to growth factor stimulus GO:0071363 39 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.022
cellular response to radiation GO:0071478 4 0.022
regulation of cell proliferation GO:0042127 37 0.021
sleep GO:0030431 1 0.021
rna localization GO:0006403 4 0.021

nf1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022