Danio rerio

0 known processes

nfkbiab

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b

(Aliases: ikbaB,wu:fb81f08,fb81f08,NFKBIA,MGC56666,zgc:77616,zgc:56666)

nfkbiab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular biosynthetic process GO:0044249 286 0.964
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.860
Human Mouse
biosynthetic process GO:0009058 294 0.828
Human Mouse Fly
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 1 0.820
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.817
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.816
Human Mouse
negative regulation of biological process GO:0048519 304 0.803
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.798
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.782
Human Mouse
regulation of response to stimulus GO:0048583 269 0.759
Human Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.753
Human Mouse Fly
signal transduction GO:0007165 455 0.736
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.708
Human Mouse
response to stress GO:0006950 263 0.670
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.653
Human Mouse Fly
gene expression GO:0010467 252 0.653
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.633
Human Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.628
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.618
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.618
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.604
Human Mouse
regulation of transcription dna templated GO:0006355 213 0.601
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.586
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.582
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.581
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.578
Human Mouse
positive regulation of biological process GO:0048518 253 0.576
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.571
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.569
Human Mouse
regulation of metabolic process GO:0019222 359 0.568
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.542
Human
response to biotic stimulus GO:0009607 97 0.519
Zebrafish Mouse Fly
negative regulation of cellular process GO:0048523 283 0.501
Human Mouse
regulation of gene expression GO:0010468 265 0.497
Human Mouse
digestive tract development GO:0048565 265 0.496
phagocytosis GO:0006909 3 0.494
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.478
Human Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.452
nucleic acid templated transcription GO:0097659 181 0.429
Human Mouse
immune system development GO:0002520 191 0.428
Mouse
regulation of biosynthetic process GO:0009889 250 0.423
Human Mouse Fly
regulation of biological quality GO:0065008 263 0.422
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.411
mesoderm development GO:0007498 88 0.410
regionalization GO:0003002 274 0.389
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.386
Mouse
response to organic substance GO:0010033 153 0.381
Mouse
heterocycle metabolic process GO:0046483 290 0.378
Human Mouse
regulation of apoptotic process GO:0042981 98 0.373
regulation of signal transduction GO:0009966 225 0.372
Human Mouse
regulation of carbohydrate metabolic process GO:0006109 4 0.362
cellular aromatic compound metabolic process GO:0006725 295 0.358
Human Mouse
rna metabolic process GO:0016070 219 0.357
Human Mouse
intracellular signal transduction GO:0035556 85 0.356
Human Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.356
Mouse
cell projection morphogenesis GO:0048858 244 0.347
negative regulation of protein phosphorylation GO:0001933 4 0.341
multi organism process GO:0051704 134 0.332
Zebrafish Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.318
Human Mouse
transcription dna templated GO:0006351 181 0.318
Human Mouse
positive regulation of cellular process GO:0048522 201 0.308
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.306
Human Mouse
regulation of production of molecular mediator of immune response GO:0002700 1 0.302
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.299
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.299
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.297
Human Mouse Fly
single organism metabolic process GO:0044710 217 0.293
regulation of rna metabolic process GO:0051252 224 0.283
Human Mouse
liver development GO:0001889 96 0.282
immune system process GO:0002376 241 0.272
Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.270
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.268
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.265
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.264
Human Mouse
digestive system development GO:0055123 289 0.263
response to external stimulus GO:0009605 264 0.262
Zebrafish Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.260
hepaticobiliary system development GO:0061008 98 0.257
regulation of signaling GO:0023051 235 0.252
Human Mouse
sphingolipid biosynthetic process GO:0030148 2 0.249
protein import into nucleus GO:0006606 3 0.247
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.244
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.243
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.242
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.237
lipid storage GO:0019915 1 0.235
Human
anterior posterior pattern specification GO:0009952 152 0.235
nuclear import GO:0051170 3 0.230
Human Mouse
death GO:0016265 121 0.230
innate immune response activating signal transduction GO:0002758 5 0.227
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.226
Human Mouse
regulation of protein metabolic process GO:0051246 56 0.223
Human
rna biosynthetic process GO:0032774 181 0.221
Human Mouse
response to virus GO:0009615 21 0.221
Zebrafish
regulation of protein transport GO:0051223 3 0.216
Human
establishment of protein localization to organelle GO:0072594 4 0.216
Human Mouse
negative regulation of rna metabolic process GO:0051253 48 0.211
cellular response to external stimulus GO:0071496 2 0.209
antimicrobial humoral response GO:0019730 2 0.209
Fly
response to other organism GO:0051707 97 0.207
Zebrafish Mouse Fly
chordate embryonic development GO:0043009 271 0.201
gland development GO:0048732 143 0.201
negative regulation of gene expression GO:0010629 65 0.200
protein metabolic process GO:0019538 183 0.200
Human
hemopoiesis GO:0030097 183 0.198
Mouse
negative regulation of cell communication GO:0010648 96 0.193
Human Mouse
nuclear transport GO:0051169 4 0.191
Human Mouse
regulation of programmed cell death GO:0043067 101 0.190
negative regulation of cytoplasmic transport GO:1903650 2 0.189
Human
defense response to other organism GO:0098542 33 0.185
Fly
regulation of protein import into nucleus GO:0042306 2 0.183
Human
single organism nuclear import GO:1902593 3 0.183
Human Mouse
gastrulation GO:0007369 208 0.181
organonitrogen compound metabolic process GO:1901564 74 0.180
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.178
Human Mouse Fly
regulation of cell differentiation GO:0045595 142 0.176
Human Mouse
somite development GO:0061053 96 0.175
negative regulation of signal transduction GO:0009968 94 0.174
Human Mouse
neuron differentiation GO:0030182 353 0.174
regulation of intracellular signal transduction GO:1902531 57 0.173
Human
positive regulation of metabolic process GO:0009893 108 0.173
Human Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.172
cell part morphogenesis GO:0032990 246 0.171
dorsal ventral pattern formation GO:0009953 125 0.171
Fly
negative regulation of developmental process GO:0051093 65 0.170
Human Mouse
larval development GO:0002164 2 0.166
response to chemical GO:0042221 320 0.165
Mouse
amide transport GO:0042886 12 0.165
Human
response to cadmium ion GO:0046686 14 0.164
reactive oxygen species biosynthetic process GO:1903409 1 0.162
regulation of cell cycle GO:0051726 52 0.161
generation of neurons GO:0048699 385 0.159
cell death GO:0008219 121 0.158
muscle organ development GO:0007517 101 0.158
segmentation GO:0035282 97 0.157
response to external biotic stimulus GO:0043207 97 0.155
Zebrafish Mouse Fly
ectodermal cell fate specification GO:0001715 2 0.155
regulation of multicellular organismal development GO:2000026 223 0.155
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.154
Fly
primitive erythrocyte differentiation GO:0060319 5 0.154
regulation of protein localization to nucleus GO:1900180 2 0.153
Human
meiotic nuclear division GO:0007126 4 0.152
regulation of cell death GO:0010941 103 0.151
positive regulation of biosynthetic process GO:0009891 68 0.151
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.147
Fly
cellular response to dna damage stimulus GO:0006974 24 0.146
Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.145
programmed cell death GO:0012501 119 0.145
negative regulation of apoptotic process GO:0043066 55 0.144
macromolecule modification GO:0043412 111 0.144
negative regulation of protein localization to nucleus GO:1900181 2 0.141
Human
phosphate containing compound metabolic process GO:0006796 108 0.141
response to radiation GO:0009314 51 0.140
maintenance of location GO:0051235 4 0.140
Human
negative regulation of phosphate metabolic process GO:0045936 13 0.139
regulation of epithelial cell proliferation GO:0050678 3 0.138
regulation of establishment of protein localization GO:0070201 4 0.137
Human
negative regulation of biosynthetic process GO:0009890 55 0.137
cellular response to chemical stimulus GO:0070887 157 0.136
Mouse
embryonic organ development GO:0048568 381 0.136
response to bacterium GO:0009617 58 0.133
Mouse
response to amino acid GO:0043200 2 0.132
somitogenesis GO:0001756 87 0.132
regulation of response to stress GO:0080134 36 0.131
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.129
sensory perception GO:0007600 39 0.128
positive regulation of transcription dna templated GO:0045893 57 0.128
Human Mouse
apoptotic process GO:0006915 116 0.127
regulation of cell communication GO:0010646 232 0.126
Human Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.126
aging GO:0007568 2 0.126
extrinsic apoptotic signaling pathway GO:0097191 3 0.125
neurological system process GO:0050877 62 0.125
single organism transport GO:0044765 206 0.122
Human Mouse Fly
cell morphogenesis GO:0000902 289 0.120
mesenchyme development GO:0060485 127 0.119
meiotic cell cycle process GO:1903046 3 0.119
membrane lipid biosynthetic process GO:0046467 2 0.118
defense response to fungus GO:0050832 2 0.118
Fly
vasculature development GO:0001944 278 0.118
cellular response to starvation GO:0009267 1 0.117
cellular protein metabolic process GO:0044267 129 0.116
Human
regulation of cytokine production GO:0001817 3 0.114
cellular response to reactive oxygen species GO:0034614 2 0.110
positive regulation of gene expression GO:0010628 71 0.110
Human Mouse
locomotion GO:0040011 313 0.108
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.108
Human
central nervous system development GO:0007417 387 0.107
protein targeting to nucleus GO:0044744 3 0.107
Human Mouse
positive regulation of transport GO:0051050 2 0.106
Human
cellular carbohydrate metabolic process GO:0044262 4 0.106
positive regulation of cell communication GO:0010647 56 0.105
negative regulation of cell death GO:0060548 60 0.104
cellular response to biotic stimulus GO:0071216 3 0.104
Mouse
protein localization GO:0008104 40 0.104
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.104
negative regulation of endopeptidase activity GO:0010951 10 0.104
regulation of multicellular organismal process GO:0051239 277 0.104
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.103
single organism biosynthetic process GO:0044711 71 0.103
positive regulation of catabolic process GO:0009896 4 0.102
carbohydrate biosynthetic process GO:0016051 1 0.102
regulation of proteolysis GO:0030162 24 0.102
reactive nitrogen species metabolic process GO:2001057 0 0.101
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.101
peptide transport GO:0015833 1 0.101
Human
meiosis i GO:0007127 1 0.101
positive regulation of rna biosynthetic process GO:1902680 57 0.101
Human Mouse
muscle cell development GO:0055001 115 0.101
primitive hemopoiesis GO:0060215 27 0.100
cellular response to stress GO:0033554 62 0.099
Fly
localization of cell GO:0051674 244 0.099
response to exogenous dsrna GO:0043330 6 0.099
Mouse
production of molecular mediator of immune response GO:0002440 2 0.099
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.098
positive regulation of rna metabolic process GO:0051254 59 0.096
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.095
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.094
Human Mouse
cellular response to extracellular stimulus GO:0031668 2 0.094
regulation of intracellular protein transport GO:0033157 3 0.093
Human
defense response to bacterium GO:0042742 22 0.092
protein import GO:0017038 3 0.092
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.092
cellular component movement GO:0006928 335 0.091
tube morphogenesis GO:0035239 349 0.091
regulation of oxidative stress induced cell death GO:1903201 2 0.091
reciprocal dna recombination GO:0035825 1 0.091
muscle fiber development GO:0048747 52 0.090
protein localization to nucleus GO:0034504 3 0.090
Human Mouse
regulation of endothelial cell proliferation GO:0001936 1 0.090
negative regulation of kinase activity GO:0033673 4 0.088
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.087
Human
organic substance transport GO:0071702 58 0.087
Human Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.086
humoral immune response GO:0006959 5 0.086
Fly
regulation of ectodermal cell fate specification GO:0042665 2 0.084
regulation of multicellular organism growth GO:0040014 4 0.084
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.083
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.082
heart development GO:0007507 313 0.082
response to nitrogen compound GO:1901698 19 0.082
Mouse
cell motility GO:0048870 244 0.082
cell proliferation GO:0008283 80 0.080
Mouse
cell migration GO:0016477 237 0.078
negative regulation of molecular function GO:0044092 23 0.078
Human
negative regulation of multicellular organismal process GO:0051241 69 0.078
Mouse
positive regulation of signaling GO:0023056 56 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.077
positive regulation of protein metabolic process GO:0051247 23 0.077
Human
positive regulation of nucleic acid templated transcription GO:1903508 57 0.076
Human Mouse
anatomical structure homeostasis GO:0060249 36 0.076
regulation of mitotic cell cycle GO:0007346 25 0.076
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.076
Human
ameboidal type cell migration GO:0001667 143 0.076
protein modification process GO:0036211 100 0.076
regulation of cytokine biosynthetic process GO:0042035 1 0.075
stem cell proliferation GO:0072089 4 0.075
negative regulation of mapk cascade GO:0043409 4 0.075
response to lipid GO:0033993 60 0.075
Mouse
microtubule organizing center organization GO:0031023 1 0.074
positive regulation of cell cycle GO:0045787 3 0.074
regulation of transport GO:0051049 45 0.074
Human
proteasomal protein catabolic process GO:0010498 2 0.073
ubiquitin dependent protein catabolic process GO:0006511 3 0.073
cellular localization GO:0051641 97 0.072
Human Mouse
inner ear development GO:0048839 126 0.072
carbohydrate metabolic process GO:0005975 12 0.072
negative regulation of rna biosynthetic process GO:1902679 45 0.071
anterior posterior axis specification GO:0009948 20 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.070
negative regulation of hydrolase activity GO:0051346 10 0.070
mitotic cell cycle GO:0000278 64 0.069
sensory organ morphogenesis GO:0090596 200 0.068
autophagy GO:0006914 4 0.068
bmp signaling pathway GO:0030509 52 0.068
positive regulation of cellular biosynthetic process GO:0031328 68 0.068
Human Mouse Fly
camera type eye development GO:0043010 222 0.067
positive regulation of signal transduction GO:0009967 56 0.067
neuron development GO:0048666 262 0.067
regulation of cell proliferation GO:0042127 37 0.067
Mouse
cellular protein catabolic process GO:0044257 4 0.067
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.067
negative regulation of intracellular protein transport GO:0090317 3 0.066
Human
negative regulation of intracellular transport GO:0032387 3 0.065
Human
cellular response to organic substance GO:0071310 105 0.064
Mouse
regulation of developmental process GO:0050793 247 0.064
Human Mouse
blood vessel morphogenesis GO:0048514 216 0.064
regulation of cytoplasmic transport GO:1903649 4 0.064
Human
regulation of ectoderm development GO:2000383 2 0.063
cellular component biogenesis GO:0044085 178 0.063
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.063
activation of innate immune response GO:0002218 6 0.063
Mouse
very long chain fatty acid metabolic process GO:0000038 4 0.062
very long chain fatty acid biosynthetic process GO:0042761 4 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.062
reactive oxygen species metabolic process GO:0072593 6 0.061
cellular response to nutrient levels GO:0031669 2 0.060
regulation of phosphorus metabolic process GO:0051174 43 0.060
negative regulation of map kinase activity GO:0043407 2 0.060
regulation of carbohydrate biosynthetic process GO:0043255 1 0.060
single organism organelle organization GO:1902589 199 0.060
nitric oxide metabolic process GO:0046209 2 0.060
activation of mapkkk activity GO:0000185 1 0.060
negative regulation of signaling GO:0023057 96 0.059
Human Mouse
endocrine system development GO:0035270 65 0.059
long chain fatty acid biosynthetic process GO:0042759 1 0.059
response to endogenous stimulus GO:0009719 83 0.058
Mouse
negative regulation of mitotic cell cycle GO:0045930 11 0.058
pancreas development GO:0031016 84 0.058
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.057
negative regulation of mitosis GO:0045839 3 0.056
head development GO:0060322 303 0.055
regulation of nucleocytoplasmic transport GO:0046822 2 0.054
Human
skeletal muscle tissue development GO:0007519 67 0.054
negative regulation of catabolic process GO:0009895 3 0.054
positive regulation of jnk cascade GO:0046330 3 0.054
regulation of anatomical structure morphogenesis GO:0022603 130 0.054
regulation of innate immune response GO:0045088 11 0.054
Mouse
negative regulation of protein import into nucleus GO:0042308 2 0.053
Human
meiotic chromosome segregation GO:0045132 3 0.053
response to growth factor GO:0070848 39 0.053
stem cell maintenance GO:0019827 4 0.053
spindle assembly GO:0051225 2 0.053
regulation of blood coagulation GO:0030193 1 0.053
dicarboxylic acid transport GO:0006835 1 0.052
axis specification GO:0009798 43 0.052
Fly
regulation of sterol transport GO:0032371 3 0.052
Human
sexual reproduction GO:0019953 36 0.051
Fly
response to lipopolysaccharide GO:0032496 13 0.051
Mouse
nephron morphogenesis GO:0072028 2 0.051
defense response GO:0006952 47 0.051
Mouse Fly
cell projection organization GO:0030030 284 0.051
neuron projection development GO:0031175 180 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.050
locomotor rhythm GO:0045475 3 0.050
cell growth GO:0016049 57 0.050
modification dependent macromolecule catabolic process GO:0043632 3 0.049
regulation of protein catabolic process GO:0042176 1 0.049
regulation of response to external stimulus GO:0032101 31 0.049
Fly
neuron projection morphogenesis GO:0048812 161 0.049
detection of abiotic stimulus GO:0009582 24 0.049
response to reactive oxygen species GO:0000302 5 0.048
estrogen metabolic process GO:0008210 2 0.048
regulation of immune response GO:0050776 14 0.048
Mouse Fly
ectoderm development GO:0007398 9 0.048
mitochondrion organization GO:0007005 4 0.047
cellular protein modification process GO:0006464 100 0.047
regulation of localization GO:0032879 104 0.047
Human
system process GO:0003008 185 0.047
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.046
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.046
response to abiotic stimulus GO:0009628 122 0.046
epithelial to mesenchymal transition GO:0001837 21 0.046
cellular response to endogenous stimulus GO:0071495 68 0.046
regulation of cell development GO:0060284 100 0.046
positive regulation of cell death GO:0010942 29 0.046
response to oxygen containing compound GO:1901700 55 0.045
Mouse
hair cell differentiation GO:0035315 32 0.045
response to light stimulus GO:0009416 46 0.045
amino acid transport GO:0006865 2 0.045
negative regulation of nucleic acid templated transcription GO:1903507 45 0.044
cell fate specification GO:0001708 68 0.044
regulation of gastrulation GO:0010470 24 0.044
cognition GO:0050890 1 0.044
negative regulation of nuclear division GO:0051784 3 0.044
cellular protein localization GO:0034613 20 0.044
Human Mouse
female gonad development GO:0008585 4 0.043
negative regulation of catalytic activity GO:0043086 21 0.042
negative regulation of protein transport GO:0051224 3 0.042
Human
regulation of defense response to virus by host GO:0050691 1 0.042
regulation of nucleotide catabolic process GO:0030811 2 0.041
myeloid cell differentiation GO:0030099 86 0.041
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.041
striated muscle cell development GO:0055002 108 0.041
regulation of stem cell proliferation GO:0072091 2 0.041
organelle fission GO:0048285 23 0.041
homeostatic process GO:0042592 142 0.041
mitotic nuclear division GO:0007067 18 0.041
skeletal muscle organ development GO:0060538 78 0.041
mechanoreceptor differentiation GO:0042490 37 0.041
regulation of wound healing GO:0061041 2 0.041
regulation of dna templated transcription in response to stress GO:0043620 0 0.041
establishment of localization in cell GO:0051649 77 0.041
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.040
cellular component assembly involved in morphogenesis GO:0010927 107 0.040
Fly
g1 s transition of mitotic cell cycle GO:0000082 1 0.040
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.040
determination of left right symmetry GO:0007368 179 0.040
single organism cellular localization GO:1902580 46 0.040
Human Mouse
renal system development GO:0072001 94 0.040
positive regulation of programmed cell death GO:0043068 29 0.040
positive regulation of response to stimulus GO:0048584 80 0.040
Mouse Fly
cytoskeleton organization GO:0007010 96 0.040
peptidyl serine modification GO:0018209 2 0.039
mesoderm formation GO:0001707 43 0.039
eye development GO:0001654 277 0.039
regulation of protein targeting GO:1903533 2 0.039
Human
regulation of cell fate commitment GO:0010453 22 0.039
response to oxidative stress GO:0006979 11 0.039
negative chemotaxis GO:0050919 1 0.039
positive regulation of apoptotic signaling pathway GO:2001235 1 0.039
regulation of nucleoside metabolic process GO:0009118 2 0.039
regulation of jak stat cascade GO:0046425 3 0.038
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.038
p38mapk cascade GO:0038066 1 0.037
neuron projection guidance GO:0097485 86 0.037
response to inorganic substance GO:0010035 38 0.037
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.037
regulation of bmp signaling pathway GO:0030510 39 0.037
mitotic cell cycle process GO:1903047 48 0.037
osteoclast differentiation GO:0030316 1 0.036
cellular response to growth factor stimulus GO:0071363 39 0.036
regulation of stem cell differentiation GO:2000736 4 0.036
multi organism reproductive process GO:0044703 36 0.036
Fly
fatty acid elongation GO:0030497 1 0.036
response to peptide GO:1901652 6 0.036
Mouse
regulation of cell migration GO:0030334 40 0.036
establishment of localization GO:0051234 244 0.036
Human Mouse Fly
regulation of reproductive process GO:2000241 4 0.036
small molecule metabolic process GO:0044281 77 0.035
protein polymerization GO:0051258 4 0.035
skin development GO:0043588 54 0.035
response to alkaloid GO:0043279 2 0.035
organelle organization GO:0006996 227 0.035
regulation of p38mapk cascade GO:1900744 1 0.035
microtubule based process GO:0007017 60 0.035
positive regulation of cell adhesion GO:0045785 1 0.035
positive regulation of neuron apoptotic process GO:0043525 1 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.034
response to molecule of bacterial origin GO:0002237 14 0.034
Mouse
negative regulation of programmed cell death GO:0043069 58 0.034
positive regulation of apoptotic process GO:0043065 29 0.034
nitrogen compound transport GO:0071705 23 0.034
Human
mesoderm morphogenesis GO:0048332 51 0.034
transport GO:0006810 220 0.033
Human Mouse Fly
notch signaling pathway GO:0007219 35 0.033
Mouse
detection of stimulus GO:0051606 29 0.033
multicellular organism growth GO:0035264 4 0.033
regulation of cysteine type endopeptidase activity GO:2000116 21 0.033
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.033
Human
cellular component disassembly GO:0022411 1 0.033
striated muscle cell differentiation GO:0051146 129 0.033
carbohydrate homeostasis GO:0033500 1 0.033
wound healing GO:0042060 90 0.032
guanosine containing compound catabolic process GO:1901069 2 0.032
erythrocyte differentiation GO:0030218 54 0.032
muscle cell differentiation GO:0042692 139 0.032
cellular macromolecule localization GO:0070727 21 0.032
Human Mouse
cell fate commitment GO:0045165 99 0.032
guanosine containing compound metabolic process GO:1901068 4 0.031
amine metabolic process GO:0009308 2 0.031
regulation of cellular protein metabolic process GO:0032268 52 0.031
Human
single organism localization GO:1902578 225 0.031
Human Mouse Fly
growth GO:0040007 174 0.031
negative regulation of cellular catabolic process GO:0031330 3 0.031
chemotaxis GO:0006935 104 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
Mouse
negative regulation of cell cycle GO:0045786 14 0.031
female sex differentiation GO:0046660 4 0.031
cell cycle GO:0007049 93 0.030
response to wounding GO:0009611 116 0.030
positive regulation of immune effector process GO:0002699 3 0.030
Fly
nitric oxide biosynthetic process GO:0006809 2 0.030
regulation of cellular protein catabolic process GO:1903362 1 0.030
tissue homeostasis GO:0001894 25 0.030
nephron epithelium morphogenesis GO:0072088 1 0.030
negative regulation of cell differentiation GO:0045596 46 0.029
Human Mouse
cytokine metabolic process GO:0042107 1 0.029
response to decreased oxygen levels GO:0036293 25 0.029
regeneration GO:0031099 91 0.029
cellular response to organonitrogen compound GO:0071417 5 0.029
hematopoietic stem cell migration GO:0035701 4 0.029
nuclear division GO:0000280 23 0.029
embryonic hemopoiesis GO:0035162 53 0.029
ectodermal cell differentiation GO:0010668 2 0.029
peripheral nervous system development GO:0007422 55 0.028
muscle tissue development GO:0060537 110 0.028
germ line stem cell maintenance GO:0030718 2 0.028
glucose import GO:0046323 2 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
muscle structure development GO:0061061 196 0.028
macromolecule localization GO:0033036 54 0.028
Human Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.028
brain development GO:0007420 293 0.028
morphogenesis of an epithelium GO:0002009 333 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
ectoderm formation GO:0001705 2 0.027
endocrine process GO:0050886 2 0.027
regulation of catalytic activity GO:0050790 55 0.027
response to glucose GO:0009749 3 0.027
gtp metabolic process GO:0046039 4 0.027
epiboly GO:0090504 41 0.027
centrosome cycle GO:0007098 1 0.027
positive regulation of gtp catabolic process GO:0033126 1 0.027

nfkbiab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.071
disease of anatomical entity DOID:7 0 0.071
primary immunodeficiency disease DOID:612 0 0.042