Danio rerio

134 known processes

nkd1

naked cuticle homolog 1 (Drosophila)

nkd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural tube formation GO:0001841 16 0.953
convergent extension GO:0060026 118 0.903
Mouse
head development GO:0060322 303 0.811
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.766
regionalization GO:0003002 274 0.735
morphogenesis of an epithelium GO:0002009 333 0.687
primary neural tube formation GO:0014020 1 0.681
regulation of cell communication GO:0010646 232 0.666
mesoderm formation GO:0001707 43 0.592
brain development GO:0007420 293 0.576
rna biosynthetic process GO:0032774 181 0.476
rostrocaudal neural tube patterning GO:0021903 29 0.458
signal transduction GO:0007165 455 0.454
determination of bilateral symmetry GO:0009855 204 0.444
heart jogging GO:0003146 40 0.416
embryonic epithelial tube formation GO:0001838 17 0.400
response to fluid shear stress GO:0034405 2 0.365
negative regulation of axon extension GO:0030517 7 0.364
neural tube patterning GO:0021532 33 0.334
cell migration involved in gastrulation GO:0042074 79 0.332
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.330
cilium assembly GO:0042384 58 0.326
gastrulation GO:0007369 208 0.309
locomotion GO:0040011 313 0.308
positive regulation of cellular process GO:0048522 201 0.306
Mouse
bmp signaling pathway GO:0030509 52 0.294
chordate embryonic development GO:0043009 271 0.291
endodermal cell fate determination GO:0007493 2 0.284
regulation of metabolic process GO:0019222 359 0.279
Human
regulation of synapse assembly GO:0051963 3 0.278
embryo development ending in birth or egg hatching GO:0009792 271 0.269
central nervous system development GO:0007417 387 0.262
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.261
tube morphogenesis GO:0035239 349 0.259
digestive tract development GO:0048565 265 0.250
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.248
negative regulation of cellular process GO:0048523 283 0.246
neural tube development GO:0021915 62 0.233
midbrain hindbrain boundary development GO:0030917 23 0.227
regulation of organ morphogenesis GO:2000027 35 0.226
Mouse
positive regulation of biological process GO:0048518 253 0.225
Human Mouse
cellular component morphogenesis GO:0032989 336 0.223
epidermal cell differentiation GO:0009913 36 0.217
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.210
regulation of mesodermal cell fate specification GO:0042661 9 0.205
regulation of multicellular organismal development GO:2000026 223 0.202
Mouse
central nervous system neuron differentiation GO:0021953 74 0.201
determination of left right symmetry GO:0007368 179 0.199
regulation of mesoderm development GO:2000380 11 0.197
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.196
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.181
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.172
Mouse
heterocycle metabolic process GO:0046483 290 0.168
morphogenesis of embryonic epithelium GO:0016331 30 0.167
epithelial tube morphogenesis GO:0060562 148 0.158
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.158
maintenance of location GO:0051235 4 0.154
regulation of canonical wnt signaling pathway GO:0060828 34 0.151
tube closure GO:0060606 1 0.151
protein metabolic process GO:0019538 183 0.148
Human
multicellular organism growth GO:0035264 4 0.148
regulation of response to stimulus GO:0048583 269 0.146
epiboly GO:0090504 41 0.143
positive regulation of map kinase activity GO:0043406 3 0.142
embryonic heart tube morphogenesis GO:0003143 108 0.139
digestive system development GO:0055123 289 0.135
negative regulation of nervous system development GO:0051961 22 0.134
mesodermal cell differentiation GO:0048333 21 0.133
convergent extension involved in gastrulation GO:0060027 71 0.133
regulation of cysteine type endopeptidase activity GO:2000116 21 0.132
regulation of signaling GO:0023051 235 0.131
death GO:0016265 121 0.130
larval development GO:0002164 2 0.129
negative regulation of neuron differentiation GO:0045665 10 0.127
negative regulation of neuron projection development GO:0010977 9 0.124
establishment of localization GO:0051234 244 0.123
negative regulation of biological process GO:0048519 304 0.121
rhombomere formation GO:0021594 12 0.120
negative regulation of chemotaxis GO:0050922 4 0.119
gall bladder development GO:0061010 1 0.119
organic acid metabolic process GO:0006082 31 0.119
regulation of establishment of planar polarity GO:0090175 4 0.112
Mouse
formation of primary germ layer GO:0001704 62 0.111
aging GO:0007568 2 0.108
determination of left right asymmetry in diencephalon GO:0035462 4 0.107
regulation of biological quality GO:0065008 263 0.106
hard palate development GO:0060022 4 0.106
left right pattern formation GO:0060972 19 0.105
divalent inorganic cation homeostasis GO:0072507 22 0.105
regulation of nodal signaling pathway GO:1900107 4 0.104
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.103
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.102
determination of left right asymmetry in nervous system GO:0035545 4 0.101
stem cell maintenance GO:0019827 4 0.101
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.097
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.095
phosphorus metabolic process GO:0006793 109 0.095
regulation of primary metabolic process GO:0080090 311 0.093
Human
regulation of synapse organization GO:0050807 3 0.093
regulation of multicellular organism growth GO:0040014 4 0.092
gpi anchor metabolic process GO:0006505 1 0.092
negative regulation of endodermal cell fate specification GO:0042664 8 0.091
tube formation GO:0035148 25 0.091
regulation of oocyte development GO:0060281 3 0.090
paraxial mesoderm development GO:0048339 8 0.089
regulation of wnt signaling pathway GO:0030111 53 0.089
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.089
positive regulation of gastrulation GO:2000543 2 0.089
positive regulation of neuron apoptotic process GO:0043525 1 0.089
anterior posterior axon guidance GO:0033564 5 0.088
negative regulation of endodermal cell differentiation GO:1903225 8 0.087
negative regulation of signal transduction GO:0009968 94 0.085
central nervous system projection neuron axonogenesis GO:0021952 15 0.084
regulation of bmp signaling pathway GO:0030510 39 0.082
wnt signaling pathway GO:0016055 80 0.081
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.079
mesoderm morphogenesis GO:0048332 51 0.078
regulation of cell differentiation GO:0045595 142 0.077
neuron projection extension GO:1990138 45 0.076
cell proliferation in midbrain GO:0033278 4 0.076
regulation of neuron differentiation GO:0045664 56 0.076
programmed cell death GO:0012501 119 0.076
aorta development GO:0035904 4 0.075
regulation of rna metabolic process GO:0051252 224 0.073
single organism organelle organization GO:1902589 199 0.073
cell cell recognition GO:0009988 1 0.073
oocyte maturation GO:0001556 4 0.073
regulation of cell death GO:0010941 103 0.073
regulation of erk1 and erk2 cascade GO:0070372 4 0.072
organonitrogen compound metabolic process GO:1901564 74 0.071
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.071
cellular carbohydrate metabolic process GO:0044262 4 0.069
regulation of hydrolase activity GO:0051336 28 0.069
dorsal convergence GO:0060030 14 0.069
regulation of endopeptidase activity GO:0052548 23 0.069
cellular macromolecule biosynthetic process GO:0034645 224 0.068
canonical wnt signaling pathway GO:0060070 48 0.067
regulation of cell cell adhesion GO:0022407 13 0.066
neural retina development GO:0003407 49 0.066
stem cell division GO:0017145 1 0.066
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.065
negative regulation of cell projection organization GO:0031345 9 0.065
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.065
optic placode formation GO:0001743 4 0.064
sensory organ morphogenesis GO:0090596 200 0.064
digestive tract morphogenesis GO:0048546 231 0.063
spinal cord anterior posterior patterning GO:0021512 1 0.062
endoderm formation GO:0001706 29 0.062
regulation of heart growth GO:0060420 2 0.061
retinal ganglion cell axon guidance GO:0031290 35 0.061
regulation of cellular metabolic process GO:0031323 320 0.060
neuroblast proliferation GO:0007405 2 0.060
central nervous system neuron axonogenesis GO:0021955 18 0.059
cell surface receptor signaling pathway GO:0007166 325 0.058
proteoglycan metabolic process GO:0006029 14 0.057
rhombomere development GO:0021546 19 0.057
establishment of organelle localization GO:0051656 45 0.057
specification of symmetry GO:0009799 204 0.056
nitrogen compound metabolic process GO:0006807 319 0.056
aromatic compound biosynthetic process GO:0019438 217 0.056
mesenchyme morphogenesis GO:0072132 5 0.056
mesoderm development GO:0007498 88 0.055
specification of axis polarity GO:0065001 4 0.055
negative regulation of muscle tissue development GO:1901862 2 0.055
negative regulation of developmental growth GO:0048640 9 0.054
Mouse
negative chemotaxis GO:0050919 1 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.054
Human
mesodermal cell fate specification GO:0007501 12 0.053
regulation of gastrulation GO:0010470 24 0.053
regulation of cellular amino acid metabolic process GO:0006521 0 0.052
regulation of gene expression GO:0010468 265 0.052
negative regulation of multicellular organismal process GO:0051241 69 0.052
rho protein signal transduction GO:0007266 5 0.052
regulation of rna biosynthetic process GO:2001141 213 0.051
sequestering of metal ion GO:0051238 3 0.051
cell morphogenesis involved in differentiation GO:0000904 195 0.050
metal ion homeostasis GO:0055065 26 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
heart morphogenesis GO:0003007 156 0.049
regulation of receptor mediated endocytosis GO:0048259 4 0.049
growth GO:0040007 174 0.047
Mouse
regulation of myelination GO:0031641 1 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.047
cellular component movement GO:0006928 335 0.046
positive regulation of cell adhesion GO:0045785 1 0.046
ectodermal placode morphogenesis GO:0071697 32 0.046
heart development GO:0007507 313 0.046
negative regulation of neurogenesis GO:0050768 20 0.046
fat soluble vitamin metabolic process GO:0006775 4 0.045
olfactory lobe development GO:0021988 4 0.045
hindbrain development GO:0030902 91 0.044
cardiocyte differentiation GO:0035051 44 0.044
positive regulation of cellular protein metabolic process GO:0032270 22 0.044
cell projection organization GO:0030030 284 0.044
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.044
localization of cell GO:0051674 244 0.043
formation of anatomical boundary GO:0048859 14 0.043
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.043
regulation of programmed cell death GO:0043067 101 0.043
ameboidal type cell migration GO:0001667 143 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
negative regulation of cell communication GO:0010648 96 0.042
gastrulation with mouth forming second GO:0001702 44 0.042
multicellular organismal macromolecule metabolic process GO:0044259 2 0.042
mesodermal cell fate commitment GO:0001710 14 0.042
rhombomere boundary formation GO:0021654 10 0.042
cardiac muscle cell differentiation GO:0055007 30 0.041
rhombomere morphogenesis GO:0021593 17 0.041
regulation of reproductive process GO:2000241 4 0.041
phosphorylation GO:0016310 69 0.041
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.041
regulation of cell adhesion GO:0030155 15 0.041
negative regulation of wnt signaling pathway GO:0030178 30 0.040
epithelial tube formation GO:0072175 19 0.040
lateral mesoderm development GO:0048368 23 0.039
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.039
regulation of growth GO:0040008 42 0.039
Mouse
germ line stem cell maintenance GO:0030718 2 0.039
immunoglobulin mediated immune response GO:0016064 3 0.037
negative regulation of nodal signaling pathway GO:1900108 4 0.037
aminoglycan metabolic process GO:0006022 9 0.036
negative regulation of synapse assembly GO:0051964 2 0.036
negative regulation of developmental process GO:0051093 65 0.036
Mouse
axon extension GO:0048675 45 0.036
defense response to fungus GO:0050832 2 0.036
macromolecule biosynthetic process GO:0009059 227 0.036
cerebellar granular layer development GO:0021681 3 0.036
chemosensory behavior GO:0007635 1 0.036
transcription dna templated GO:0006351 181 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.035
posterior lateral line development GO:0048916 38 0.035
anterior posterior pattern specification GO:0009952 152 0.035
regulation of synapse structure and activity GO:0050803 5 0.035
cilium morphogenesis GO:0060271 85 0.034
pancreas development GO:0031016 84 0.034
regulation of peptidase activity GO:0052547 23 0.034
cell projection morphogenesis GO:0048858 244 0.033
apoptotic process involved in development GO:1902742 2 0.033
regulation of cell size GO:0008361 29 0.033
positive regulation of bmp signaling pathway GO:0030513 10 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
oxoacid metabolic process GO:0043436 31 0.033
regulation of cellular protein metabolic process GO:0032268 52 0.032
regulation of cardiac muscle tissue development GO:0055024 1 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
Mouse
sulfur compound metabolic process GO:0006790 13 0.032
ras protein signal transduction GO:0007265 7 0.032
cilium organization GO:0044782 71 0.032
organelle organization GO:0006996 227 0.032
regulation of signal transduction GO:0009966 225 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.031
sensory organ development GO:0007423 393 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
rhombomere 4 development GO:0021570 5 0.031
embryonic organ development GO:0048568 381 0.031
gland development GO:0048732 143 0.031
neuron projection morphogenesis GO:0048812 161 0.031
hindbrain formation GO:0021576 3 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
regulation of type b pancreatic cell proliferation GO:0061469 1 0.030
cell morphogenesis GO:0000902 289 0.030
kupffer s vesicle development GO:0070121 50 0.030
spemann organizer formation GO:0060061 10 0.030
kidney epithelium development GO:0072073 23 0.030
mesodermal cell migration GO:0008078 12 0.029
activation of mapk activity GO:0000187 3 0.029
negative regulation of cell fate specification GO:0009996 11 0.029
neural precursor cell proliferation GO:0061351 20 0.029
cell death GO:0008219 121 0.029
cellular amine metabolic process GO:0044106 2 0.029
negative regulation of reproductive process GO:2000242 3 0.029
anterior head development GO:0097065 2 0.029
negative regulation of cell differentiation GO:0045596 46 0.029
negative regulation of bmp signaling pathway GO:0030514 13 0.029
small gtpase mediated signal transduction GO:0007264 8 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.028
regulation of neuron projection development GO:0010975 40 0.028
regulation of cell development GO:0060284 100 0.028
pathway restricted smad protein phosphorylation GO:0060389 1 0.028
dorsal ventral neural tube patterning GO:0021904 1 0.028
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.028
nucleic acid metabolic process GO:0090304 244 0.028
cellular protein metabolic process GO:0044267 129 0.028
generation of neurons GO:0048699 385 0.027
embryonic eye morphogenesis GO:0048048 30 0.027
embryonic limb morphogenesis GO:0030326 2 0.027
eye development GO:0001654 277 0.027
hormone transport GO:0009914 2 0.027
positive regulation of neuron death GO:1901216 1 0.027
fat soluble vitamin biosynthetic process GO:0042362 2 0.026
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.026
somatic muscle development GO:0007525 4 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
regulation of nervous system development GO:0051960 90 0.026
epithelial cilium movement GO:0003351 15 0.026
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.026
release of sequestered calcium ion into cytosol GO:0051209 3 0.026
otic placode formation GO:0043049 23 0.026
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.026
positive regulation of mesodermal cell fate specification GO:0048337 1 0.025
catabolic process GO:0009056 32 0.025
Human
neuron differentiation GO:0030182 353 0.025
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.025
sequestering of calcium ion GO:0051208 3 0.025
regulation of activin receptor signaling pathway GO:0032925 5 0.024
olfactory bulb development GO:0021772 4 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
proteoglycan biosynthetic process GO:0030166 12 0.024
small molecule metabolic process GO:0044281 77 0.024
cellular localization GO:0051641 97 0.024
organic substance biosynthetic process GO:1901576 289 0.024
negative regulation of collateral sprouting GO:0048671 2 0.024
amine metabolic process GO:0009308 2 0.024
post embryonic organ development GO:0048569 4 0.024
cellular component maintenance GO:0043954 3 0.024
cell part morphogenesis GO:0032990 246 0.024
regulation of proteolysis GO:0030162 24 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
endothelial cell fate commitment GO:0060839 3 0.023
cell migration GO:0016477 237 0.023
transport GO:0006810 220 0.023
type b pancreatic cell development GO:0003323 4 0.023
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.023
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
cardiac muscle tissue development GO:0048738 48 0.023
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.023
positive regulation of striated muscle tissue development GO:0045844 1 0.023
non canonical wnt signaling pathway GO:0035567 13 0.023
Mouse
paraxial mesoderm morphogenesis GO:0048340 2 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
cellular response to retinoic acid GO:0071300 1 0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.022
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.022
biosynthetic process GO:0009058 294 0.022
response to chemical GO:0042221 320 0.022
multicellular organism reproduction GO:0032504 35 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
negative regulation of cell development GO:0010721 26 0.022
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.021
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.021
sulfur compound biosynthetic process GO:0044272 9 0.021
mediolateral intercalation GO:0060031 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
developmental programmed cell death GO:0010623 4 0.021
proteolysis GO:0006508 38 0.020
blood vessel development GO:0001568 246 0.020
regulation of multicellular organismal metabolic process GO:0044246 2 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
foregut morphogenesis GO:0007440 4 0.020
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.020
negative regulation of gastrulation GO:2000542 11 0.020
regulation of sequestering of calcium ion GO:0051282 4 0.020
otic vesicle development GO:0071599 42 0.020
connective tissue development GO:0061448 99 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
photoreceptor cell fate commitment GO:0046552 1 0.020
defense response to other organism GO:0098542 33 0.020
paraxial mesoderm formation GO:0048341 2 0.020
positive regulation of mesoderm development GO:2000382 1 0.020
protein activation cascade GO:0072376 6 0.020
neutrophil migration GO:1990266 10 0.019
cell proliferation involved in heart morphogenesis GO:0061323 2 0.019
apoptotic process GO:0006915 116 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
determination of dorsal ventral asymmetry GO:0048262 34 0.019
transmission of nerve impulse GO:0019226 19 0.019
positive regulation of synapse assembly GO:0051965 1 0.019
apoptotic process involved in morphogenesis GO:0060561 2 0.019
ventricular system development GO:0021591 12 0.019
positive regulation of stress activated mapk cascade GO:0032874 3 0.019
regulation of biosynthetic process GO:0009889 250 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Mouse
nucleic acid templated transcription GO:0097659 181 0.018
positive regulation of apoptotic process GO:0043065 29 0.018
multicellular organismal signaling GO:0035637 22 0.018
optic placode formation involved in camera type eye formation GO:0046619 3 0.018
determination of liver left right asymmetry GO:0071910 11 0.018
regulation of phosphorus metabolic process GO:0051174 43 0.018
cell proliferation in forebrain GO:0021846 3 0.018
negative regulation of axonogenesis GO:0050771 7 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
positive regulation of locomotion GO:0040017 14 0.018
embryonic foregut morphogenesis GO:0048617 1 0.018
positive regulation of oocyte development GO:0060282 1 0.018
heart field specification GO:0003128 1 0.018
cellular response to estradiol stimulus GO:0071392 1 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.017
positive regulation of jun kinase activity GO:0043507 2 0.017
regulation of cell activation GO:0050865 1 0.017
chemotaxis GO:0006935 104 0.017
ectodermal placode formation GO:0060788 26 0.017
negative regulation of axon regeneration GO:0048681 4 0.017
pronephros morphogenesis GO:0072114 14 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
somite development GO:0061053 96 0.017
embryonic hemopoiesis GO:0035162 53 0.017
neural plate regionalization GO:0060897 10 0.017
central nervous system formation GO:0021556 1 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
aminoglycan biosynthetic process GO:0006023 8 0.016
cellular response to organic substance GO:0071310 105 0.016
regulation of anterior head development GO:2000742 2 0.016
cell proliferation in hindbrain GO:0021534 4 0.016
granulocyte migration GO:0097530 11 0.016
negative regulation of metabolic process GO:0009892 86 0.016
single organism reproductive process GO:0044702 40 0.016
carbohydrate derivative biosynthetic process GO:1901137 43 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
negative regulation of muscle organ development GO:0048635 5 0.016
cytoskeleton organization GO:0007010 96 0.016
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 1 0.016
hatching GO:0035188 4 0.016
protein localization to plasma membrane GO:0072659 1 0.016
calcium ion homeostasis GO:0055074 19 0.016
mesenchyme development GO:0060485 127 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
response to external biotic stimulus GO:0043207 97 0.016
positive regulation of neuron projection development GO:0010976 9 0.016
nodal signaling pathway GO:0038092 7 0.016
skeletal system morphogenesis GO:0048705 102 0.016
regulation of cellular component organization GO:0051128 86 0.015
pericardium morphogenesis GO:0003344 1 0.015
cell cycle GO:0007049 93 0.015
positive regulation of cell cycle GO:0045787 3 0.015
pectoral fin development GO:0033339 50 0.015
protein targeting to nucleus GO:0044744 3 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
regulation of organelle organization GO:0033043 29 0.015
cellular response to fluid shear stress GO:0071498 1 0.015
cranial nerve morphogenesis GO:0021602 15 0.015
cellular homeostasis GO:0019725 26 0.015
liver development GO:0001889 96 0.015
regulation of developmental growth GO:0048638 38 0.015
Mouse
homeostatic process GO:0042592 142 0.015
negative regulation of cellular component organization GO:0051129 16 0.015
cell cell signaling involved in cell fate commitment GO:0045168 12 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
regulation of cardiac muscle cell differentiation GO:2000725 1 0.014
embryonic camera type eye formation GO:0060900 10 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
embryonic heart tube development GO:0035050 133 0.014
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.014
peptide transport GO:0015833 1 0.014
spindle localization GO:0051653 12 0.014
heart looping GO:0001947 94 0.014
midbrain development GO:0030901 28 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
septum transversum development GO:0003343 4 0.014
neuron development GO:0048666 262 0.014
positive regulation of muscle organ development GO:0048636 1 0.014
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
fourth ventricle development GO:0021592 8 0.014
pronephros development GO:0048793 69 0.013
single organismal cell cell adhesion GO:0016337 29 0.013
embryonic camera type eye development GO:0031076 29 0.013
rhombomere 5 development GO:0021571 4 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
synapse assembly GO:0007416 9 0.013
single organism localization GO:1902578 225 0.013
appendage development GO:0048736 80 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
Human
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
rna metabolic process GO:0016070 219 0.013
positive regulation of programmed cell death GO:0043068 29 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
carbohydrate homeostasis GO:0033500 1 0.013
immune system process GO:0002376 241 0.013
regulation of locomotion GO:0040012 55 0.013
digestive tract mesoderm development GO:0007502 1 0.013
regulation of biomineral tissue development GO:0070167 2 0.013
multicellular organismal reproductive process GO:0048609 35 0.012
type b pancreatic cell proliferation GO:0044342 1 0.012
regulation of bone mineralization GO:0030500 2 0.012
single organism metabolic process GO:0044710 217 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
hepatic duct development GO:0061011 2 0.012
reproduction GO:0000003 40 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
Mouse
cartilage development GO:0051216 96 0.012

nkd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
musculoskeletal system disease DOID:17 0 0.085
connective tissue disease DOID:65 0 0.085
bone disease DOID:0080001 0 0.060
bone development disease DOID:0080006 0 0.048
dysostosis DOID:1934 0 0.048
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026