Danio rerio

0 known processes

nnt

nicotinamide nucleotide transhydrogenase

(Aliases: wu:fa20d10,wu:fc86a04,zgc:76979)

nnt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.440
regulation of mrna splicing via spliceosome GO:0048024 3 0.111
aging GO:0007568 2 0.111
cellular respiration GO:0045333 3 0.111
microtubule organizing center organization GO:0031023 1 0.106
fertilization GO:0009566 3 0.103
regulation of mrna processing GO:0050684 3 0.100
locomotion GO:0040011 313 0.099
maintenance of location GO:0051235 4 0.091
organelle organization GO:0006996 227 0.087
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.085
establishment of localization GO:0051234 244 0.082
centrosome organization GO:0051297 1 0.080
nuclear migration GO:0007097 3 0.078
embryo development ending in birth or egg hatching GO:0009792 271 0.077
single fertilization GO:0007338 3 0.076
spermatid development GO:0007286 2 0.075
mitochondrion organization GO:0007005 4 0.069
pole plasm assembly GO:0007315 4 0.069
germ line stem cell maintenance GO:0030718 2 0.065
protein complex subunit organization GO:0071822 46 0.060
cellular biosynthetic process GO:0044249 286 0.057
maternal determination of anterior posterior axis embryo GO:0008358 4 0.053
regulation of biological quality GO:0065008 263 0.053
regulation of establishment of protein localization GO:0070201 4 0.053
negative regulation of biological process GO:0048519 304 0.051
regulation of macromolecule metabolic process GO:0060255 317 0.050
localization of cell GO:0051674 244 0.049
multicellular organism growth GO:0035264 4 0.049
carboxylic acid metabolic process GO:0019752 22 0.048
regulation of gene expression GO:0010468 265 0.047
protein glycosylation GO:0006486 9 0.047
organism emergence from protective structure GO:0071684 4 0.046
regulation of multicellular organism growth GO:0040014 4 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.045
cytoskeleton organization GO:0007010 96 0.045
pronuclear migration GO:0035046 1 0.044
protein localization to nucleus GO:0034504 3 0.044
lipid storage GO:0019915 1 0.044
positive regulation of transport GO:0051050 2 0.044
cellular component assembly GO:0022607 170 0.044
protein polymerization GO:0051258 4 0.044
cytokinesis GO:0000910 3 0.042
organic substance biosynthetic process GO:1901576 289 0.042
regulation of stem cell differentiation GO:2000736 4 0.042
response to drug GO:0042493 3 0.041
protein import GO:0017038 3 0.041
spermatid differentiation GO:0048515 2 0.040
translational initiation GO:0006413 3 0.040
actin polymerization or depolymerization GO:0008154 2 0.039
stem cell division GO:0017145 1 0.038
negative regulation of cytoplasmic transport GO:1903650 2 0.037
oxoacid metabolic process GO:0043436 31 0.037
meiotic nuclear division GO:0007126 4 0.036
cell motility GO:0048870 244 0.036
phagocytosis GO:0006909 3 0.036
negative regulation of intracellular transport GO:0032387 3 0.035
protein complex assembly GO:0006461 30 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.034
protein n linked glycosylation GO:0006487 1 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.034
muscle cell differentiation GO:0042692 139 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
oocyte anterior posterior axis specification GO:0007314 4 0.032
single organism localization GO:1902578 225 0.032
regulation of protein transport GO:0051223 3 0.032
stem cell maintenance GO:0019827 4 0.032
nucleoside monophosphate catabolic process GO:0009125 4 0.031
positive regulation of secretion GO:0051047 1 0.031
transmembrane transport GO:0055085 120 0.031
cellular component disassembly GO:0022411 1 0.030
ribonucleoside monophosphate catabolic process GO:0009158 4 0.029
myosin filament assembly GO:0031034 6 0.029
single organism metabolic process GO:0044710 217 0.029
Human
cellular amine metabolic process GO:0044106 2 0.027
sensory organ development GO:0007423 393 0.027
microtubule based process GO:0007017 60 0.027
lamellipodium assembly GO:0030032 1 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
cellular protein complex assembly GO:0043623 19 0.026
transport GO:0006810 220 0.026
apoptotic process GO:0006915 116 0.026
regulation of oocyte development GO:0060281 3 0.026
small molecule metabolic process GO:0044281 77 0.026
atp catabolic process GO:0006200 4 0.025
organic acid metabolic process GO:0006082 31 0.025
striated muscle cell differentiation GO:0051146 129 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.024
cellular component movement GO:0006928 335 0.024
mitochondrial transport GO:0006839 2 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
gene expression GO:0010467 252 0.023
cellular component biogenesis GO:0044085 178 0.022
protein import into nucleus GO:0006606 3 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
regulation of protein complex assembly GO:0043254 3 0.022
oogenesis GO:0048477 14 0.022
cell substrate adhesion GO:0031589 4 0.022
regulation of protein catabolic process GO:0042176 1 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
lamellipodium organization GO:0097581 1 0.021
actin filament polymerization GO:0030041 2 0.021
glycoprotein metabolic process GO:0009100 23 0.021
positive regulation of dna metabolic process GO:0051054 1 0.021
gland development GO:0048732 143 0.020
regulation of reproductive process GO:2000241 4 0.020
glycoprotein biosynthetic process GO:0009101 21 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
protein complex biogenesis GO:0070271 30 0.020
rna localization GO:0006403 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
inner ear development GO:0048839 126 0.019
negative regulation of metabolic process GO:0009892 86 0.019
carbohydrate derivative biosynthetic process GO:1901137 43 0.019
protein stabilization GO:0050821 2 0.019
cellular transition metal ion homeostasis GO:0046916 3 0.019
acyl coa metabolic process GO:0006637 1 0.019
cell projection organization GO:0030030 284 0.019
pyruvate metabolic process GO:0006090 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
acetyl coa metabolic process GO:0006084 1 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
cellular response to external stimulus GO:0071496 2 0.019
regulation of wound healing GO:0061041 2 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
regulation of cell shape GO:0008360 1 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
protein complex disassembly GO:0043241 1 0.018
heterocycle metabolic process GO:0046483 290 0.018
microtubule cytoskeleton organization GO:0000226 33 0.018
positive regulation of biological process GO:0048518 253 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
positive regulation of jak stat cascade GO:0046427 2 0.018
negative regulation of gene expression GO:0010629 65 0.018
signal transduction GO:0007165 455 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
transcription dna templated GO:0006351 181 0.018
macromolecule glycosylation GO:0043413 9 0.017
nuclear transport GO:0051169 4 0.017
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
protein localization to plasma membrane GO:0072659 1 0.017
cellular protein metabolic process GO:0044267 129 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
ear development GO:0043583 127 0.017
nuclear import GO:0051170 3 0.017
response to chemical GO:0042221 320 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
endosomal transport GO:0016197 2 0.017
membrane invagination GO:0010324 1 0.017
cell migration GO:0016477 237 0.017
positive regulation of catabolic process GO:0009896 4 0.017
negative regulation of catabolic process GO:0009895 3 0.017
regulation of metal ion transport GO:0010959 4 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
methylation GO:0032259 22 0.017
glycosylation GO:0070085 11 0.016
regulation of chromosome segregation GO:0051983 1 0.016
cognition GO:0050890 1 0.016
er to golgi vesicle mediated transport GO:0006888 1 0.016
adult behavior GO:0030534 2 0.016
regulation of protein polymerization GO:0032271 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
nephron morphogenesis GO:0072028 2 0.016
regulation of protein binding GO:0043393 3 0.016
multi organism process GO:0051704 134 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
lateral inhibition GO:0046331 1 0.016
amine metabolic process GO:0009308 2 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of localization GO:0032879 104 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
specification of symmetry GO:0009799 204 0.016
germ cell development GO:0007281 22 0.015
energy reserve metabolic process GO:0006112 2 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
protein homooligomerization GO:0051260 3 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cellular response to retinoic acid GO:0071300 1 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
single organism organelle organization GO:1902589 199 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of mesenchymal cell proliferation GO:0010464 1 0.015
camera type eye development GO:0043010 222 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
myofibril assembly GO:0030239 48 0.015
cellular ketone metabolic process GO:0042180 11 0.015
heart development GO:0007507 313 0.015
regulation of protein targeting GO:1903533 2 0.015
regulation of metabolic process GO:0019222 359 0.015
cell matrix adhesion GO:0007160 4 0.015
detection of stimulus GO:0051606 29 0.015
protein heterooligomerization GO:0051291 1 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
macromolecular complex assembly GO:0065003 35 0.014
centrosome cycle GO:0007098 1 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.014
regulation of receptor mediated endocytosis GO:0048259 4 0.014
epidermal cell differentiation GO:0009913 36 0.014
keratinocyte differentiation GO:0030216 0 0.014
developmental programmed cell death GO:0010623 4 0.014
protein metabolic process GO:0019538 183 0.014
renal tubule morphogenesis GO:0061333 1 0.014
sexual reproduction GO:0019953 36 0.014
neurological system process GO:0050877 62 0.014
estrogen metabolic process GO:0008210 2 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
regulation of primary metabolic process GO:0080090 311 0.014
meiotic cell cycle process GO:1903046 3 0.014
system process GO:0003008 185 0.014
golgi vesicle transport GO:0048193 3 0.014
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.013
regulation of binding GO:0051098 3 0.013
stem cell proliferation GO:0072089 4 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
hatching GO:0035188 4 0.013
response to amino acid GO:0043200 2 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
atp synthesis coupled electron transport GO:0042773 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
adherens junction organization GO:0034332 4 0.013
muscle structure development GO:0061061 196 0.013
response to external stimulus GO:0009605 264 0.013
protein targeting to nucleus GO:0044744 3 0.013
urogenital system development GO:0001655 97 0.013
protein secretion GO:0009306 1 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cellular localization GO:0051641 97 0.013
cell death GO:0008219 121 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
apoptotic process involved in development GO:1902742 2 0.013
protein complex localization GO:0031503 1 0.013
detection of external stimulus GO:0009581 24 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
acyl coa biosynthetic process GO:0071616 1 0.013
positive regulation of cell cycle GO:0045787 3 0.013
primary neural tube formation GO:0014020 1 0.013
protein depolymerization GO:0051261 1 0.013
mrna splicing via spliceosome GO:0000398 10 0.013
phagocytosis engulfment GO:0006911 1 0.013
thioester metabolic process GO:0035383 1 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
vasculature development GO:0001944 278 0.012
positive regulation of translation GO:0045727 1 0.012
cellular response to starvation GO:0009267 1 0.012
cytoplasm organization GO:0007028 4 0.012
specification of axis polarity GO:0065001 4 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
renal system development GO:0072001 94 0.012
negative regulation of kinase activity GO:0033673 4 0.012
apoptotic process involved in morphogenesis GO:0060561 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
mitotic cell cycle GO:0000278 64 0.012
blood vessel development GO:0001568 246 0.012
regulation of calcium ion transport GO:0051924 2 0.012
organelle localization GO:0051640 49 0.012
regulation of jak stat cascade GO:0046425 3 0.012
regulation of cell activation GO:0050865 1 0.012
syncytium formation GO:0006949 12 0.012
eye development GO:0001654 277 0.011
nuclear division GO:0000280 23 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of cell maturation GO:1903429 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
kidney development GO:0001822 92 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
regulation of synapse assembly GO:0051963 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
activation of mapk activity GO:0000187 3 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
morphogenesis of an epithelial fold GO:0060571 1 0.011
single organism transport GO:0044765 206 0.011
myosin filament organization GO:0031033 6 0.011
regulation of gene silencing GO:0060968 1 0.011
cellular amide metabolic process GO:0043603 4 0.011
protein modification by small protein removal GO:0070646 1 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
spindle localization GO:0051653 12 0.011
actin filament based process GO:0030029 64 0.011
response to topologically incorrect protein GO:0035966 2 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
neuroblast proliferation GO:0007405 2 0.011
cellular protein complex disassembly GO:0043624 1 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
single organism nuclear import GO:1902593 3 0.011
autophagy GO:0006914 4 0.011
developmental growth GO:0048589 166 0.011
liver development GO:0001889 96 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
exocytosis GO:0006887 1 0.011
neutrophil mediated immunity GO:0002446 1 0.011
negative regulation of blood circulation GO:1903523 2 0.011
regulation of jun kinase activity GO:0043506 3 0.011
spindle assembly GO:0051225 2 0.011
regulation of dna replication GO:0006275 3 0.011
establishment of organelle localization GO:0051656 45 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
electron transport chain GO:0022900 2 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
positive regulation of cell division GO:0051781 2 0.010
single organism cellular localization GO:1902580 46 0.010
regulation of blood pressure GO:0008217 1 0.010
gamete generation GO:0007276 33 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
establishment of rna localization GO:0051236 3 0.010
positive regulation of wound healing GO:0090303 1 0.010
segmentation GO:0035282 97 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
detection of abiotic stimulus GO:0009582 24 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
striated muscle cell development GO:0055002 108 0.010
cell junction maintenance GO:0034331 2 0.010
negative regulation of nuclear division GO:0051784 3 0.010
phototransduction GO:0007602 2 0.010
response to fluid shear stress GO:0034405 2 0.010
lymphocyte proliferation GO:0046651 1 0.010

nnt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.023
musculoskeletal system disease DOID:17 0 0.017
inherited metabolic disorder DOID:655 0 0.016
amino acid metabolic disorder DOID:9252 0 0.015
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011