Danio rerio

68 known processes

notch1b

notch homolog 1b

(Aliases: etID309871.5,wu:fc55e11)

notch1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.993
Human Mouse Rat Fly
regulation of primary metabolic process GO:0080090 311 0.919
Human Mouse Rat Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.850
Human Mouse Rat Fly
regulation of biosynthetic process GO:0009889 250 0.791
Human Mouse Rat Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.779
Human Mouse Rat Fly
epithelial cell differentiation GO:0030855 116 0.777
Mouse Rat Fly
heart morphogenesis GO:0003007 156 0.768
Human Mouse Rat
vasculature development GO:0001944 278 0.761
embryonic heart tube morphogenesis GO:0003143 108 0.746
Mouse
ear development GO:0043583 127 0.723
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.720
Human Mouse Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.718
Human Mouse Rat Fly
embryonic heart tube development GO:0035050 133 0.703
Mouse
cell fate specification GO:0001708 68 0.683
Zebrafish Mouse Worm Fly
pericardium morphogenesis GO:0003344 1 0.676
Mouse
nucleic acid metabolic process GO:0090304 244 0.672
Human Mouse Rat Fly
aromatic compound biosynthetic process GO:0019438 217 0.670
Human Mouse Rat Fly
embryonic organ morphogenesis GO:0048562 274 0.660
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.649
Human Mouse Rat Fly
determination of left right symmetry GO:0007368 179 0.643
Zebrafish Mouse
gene expression GO:0010467 252 0.642
Human Mouse Rat Fly
regulation of macromolecule metabolic process GO:0060255 317 0.640
Human Mouse Rat Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.638
Human Mouse Rat Fly
negative regulation of biological process GO:0048519 304 0.634
blood vessel morphogenesis GO:0048514 216 0.625
Human Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.623
regulation of gene expression GO:0010468 265 0.597
Human Mouse Rat Fly
morphogenesis of an epithelium GO:0002009 333 0.596
Mouse Fly
rna metabolic process GO:0016070 219 0.595
Human Mouse Rat Fly
actin filament based process GO:0030029 64 0.593
Fly
determination of bilateral symmetry GO:0009855 204 0.582
Zebrafish Mouse
sensory organ development GO:0007423 393 0.563
Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.561
Human Mouse Rat Fly
heterocycle metabolic process GO:0046483 290 0.546
Human Mouse Rat Fly
locomotion GO:0040011 313 0.543
Human Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.540
regulation of rna biosynthetic process GO:2001141 213 0.534
Human Mouse Rat Fly
positive regulation of muscle tissue development GO:1901863 1 0.533
Mouse
blood vessel development GO:0001568 246 0.518
glomerulus vasculature development GO:0072012 2 0.516
Mouse
nitrogen compound metabolic process GO:0006807 319 0.516
Human Mouse Rat Fly
regulation of multicellular organismal process GO:0051239 277 0.510
Human Zebrafish Mouse Rat Fly
cell fate commitment GO:0045165 99 0.497
Zebrafish Mouse Worm Fly
cellular component morphogenesis GO:0032989 336 0.496
digestive tract morphogenesis GO:0048546 231 0.491
Zebrafish Mouse Fly
neural tube development GO:0021915 62 0.487
Mouse
angiogenesis GO:0001525 158 0.478
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.477
Human Mouse Rat Fly
aging GO:0007568 2 0.476
Worm Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.461
Human Mouse Rat Fly
cardiac muscle tissue development GO:0048738 48 0.455
Mouse
embryonic organ development GO:0048568 381 0.449
Zebrafish Mouse Fly
response to chemical GO:0042221 320 0.446
Human Mouse Rat Fly
biological adhesion GO:0022610 40 0.439
Human Fly
striated muscle tissue development GO:0014706 110 0.439
Human Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.421
Zebrafish Mouse Worm
specification of symmetry GO:0009799 204 0.421
Zebrafish Mouse
response to hormone GO:0009725 48 0.421
Human Rat
regulation of epithelial cell proliferation GO:0050678 3 0.420
Mouse
cell substrate adhesion GO:0031589 4 0.407
Human
photoreceptor cell fate commitment GO:0046552 1 0.399
regulation of nucleic acid templated transcription GO:1903506 213 0.396
Human Mouse Rat Fly
skeletal system development GO:0001501 181 0.391
Zebrafish
chordate embryonic development GO:0043009 271 0.391
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.382
Human Mouse Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.372
Human Mouse Rat Fly
retina development in camera type eye GO:0060041 146 0.372
regulation of signaling GO:0023051 235 0.371
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.369
Human Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.368
Human Mouse Rat Fly
cell projection organization GO:0030030 284 0.361
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.359
Mouse
neuron projection development GO:0031175 180 0.352
mesenchymal cell development GO:0014031 78 0.349
Human Mouse
positive regulation of striated muscle tissue development GO:0045844 1 0.341
Mouse
heart process GO:0003015 71 0.340
stem cell development GO:0048864 82 0.339
regulation of rna metabolic process GO:0051252 224 0.337
Human Mouse Rat Fly
heterocycle biosynthetic process GO:0018130 215 0.333
Human Mouse Rat Fly
rna biosynthetic process GO:0032774 181 0.333
Human Mouse Rat Fly
regulation of blood circulation GO:1903522 32 0.329
regulation of cell differentiation GO:0045595 142 0.326
sensory organ morphogenesis GO:0090596 200 0.323
Fly
regulation of metabolic process GO:0019222 359 0.318
Human Mouse Rat Fly
regulation of cellular biosynthetic process GO:0031326 245 0.318
Human Mouse Rat Fly
cell motility GO:0048870 244 0.314
Human Mouse Fly
regulation of cell communication GO:0010646 232 0.314
Mouse Fly
heart contraction GO:0060047 71 0.307
neuron differentiation GO:0030182 353 0.300
heart looping GO:0001947 94 0.299
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.298
Human Mouse Rat Fly
muscle tissue development GO:0060537 110 0.293
Human Mouse Fly
regulation of heart contraction GO:0008016 32 0.292
stem cell differentiation GO:0048863 117 0.285
mesoderm development GO:0007498 88 0.281
Zebrafish Fly
anterior posterior pattern specification GO:0009952 152 0.279
Zebrafish Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.277
Human Mouse Rat Fly
atrioventricular valve formation GO:0003190 3 0.275
Human
regulation of skeletal muscle tissue development GO:0048641 4 0.273
Human
stem cell proliferation GO:0072089 4 0.271
Rat
mesenchymal cell differentiation GO:0048762 87 0.268
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.268
Human Zebrafish Mouse Rat Fly
regulation of localization GO:0032879 104 0.267
Human Zebrafish Mouse
heart valve formation GO:0003188 4 0.264
Human
positive regulation of rna biosynthetic process GO:1902680 57 0.262
Human Mouse Rat Fly
biosynthetic process GO:0009058 294 0.253
Human Mouse Rat Fly
cardiac atrium morphogenesis GO:0003209 2 0.251
Mouse
aorta morphogenesis GO:0035909 3 0.250
aorta development GO:0035904 4 0.247
positive regulation of metabolic process GO:0009893 108 0.242
Human Mouse Rat Fly
regulation of protein complex assembly GO:0043254 3 0.239
eye development GO:0001654 277 0.236
Fly
signal transduction GO:0007165 455 0.236
Human Zebrafish Mouse Rat Fly
cellular biosynthetic process GO:0044249 286 0.235
Human Mouse Rat Fly
transcription dna templated GO:0006351 181 0.234
Human Mouse Rat Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.232
Human Mouse Rat Fly
digestive tract development GO:0048565 265 0.230
Zebrafish Mouse Worm Fly
specification of organ position GO:0010159 3 0.228
blood circulation GO:0008015 87 0.227
Zebrafish
cellular component movement GO:0006928 335 0.227
Human Mouse Fly
positive regulation of gene expression GO:0010628 71 0.227
Human Mouse Rat Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.223
Mouse Fly
trabecula morphogenesis GO:0061383 2 0.223
Mouse
response to organic substance GO:0010033 153 0.222
Human Mouse Rat
camera type eye development GO:0043010 222 0.221
cellular response to chemical stimulus GO:0070887 157 0.221
Human Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.215
Human Mouse
immune system development GO:0002520 191 0.215
Mouse Fly
bmp signaling pathway GO:0030509 52 0.213
Mouse
immune system process GO:0002376 241 0.213
Mouse Fly
digestive system development GO:0055123 289 0.213
Zebrafish Mouse Worm Fly
neural crest cell development GO:0014032 62 0.212
head development GO:0060322 303 0.209
organic substance biosynthetic process GO:1901576 289 0.207
Human Mouse Rat Fly
reproduction GO:0000003 40 0.206
Rat Worm Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.203
Mouse
regulation of organ growth GO:0046620 3 0.202
Mouse
macromolecule biosynthetic process GO:0009059 227 0.201
Human Mouse Rat Fly
cardiac cell development GO:0055006 21 0.201
Mouse
inner ear development GO:0048839 126 0.200
Mouse
central nervous system development GO:0007417 387 0.199
regulation of transcription dna templated GO:0006355 213 0.193
Human Mouse Rat Fly
response to oxygen containing compound GO:1901700 55 0.191
Mouse Rat
ear morphogenesis GO:0042471 64 0.191
inner ear morphogenesis GO:0042472 63 0.191
cellular component assembly GO:0022607 170 0.189
Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.188
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.186
Human Mouse Rat Fly
endoderm development GO:0007492 49 0.180
Zebrafish Mouse
homeostasis of number of cells GO:0048872 62 0.179
Fly
striated muscle cell differentiation GO:0051146 129 0.176
Human Mouse
endocardial cushion formation GO:0003272 2 0.174
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.174
Human Mouse Rat Fly
actin cytoskeleton organization GO:0030036 63 0.172
Fly
organelle assembly GO:0070925 110 0.172
homeostatic process GO:0042592 142 0.170
Fly
cartilage development GO:0051216 96 0.168
Zebrafish
tube morphogenesis GO:0035239 349 0.166
Human Zebrafish Mouse Fly
axon development GO:0061564 166 0.165
regulation of cellular metabolic process GO:0031323 320 0.163
Human Mouse Rat Fly
pericardium development GO:0060039 1 0.160
Mouse
endodermal cell fate specification GO:0001714 17 0.159
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.158
Human Mouse Rat Fly
eye morphogenesis GO:0048592 144 0.158
Fly
skin development GO:0043588 54 0.154
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.150
Human Mouse Rat Fly
atrioventricular valve morphogenesis GO:0003181 6 0.149
Human Mouse
positive regulation of biosynthetic process GO:0009891 68 0.146
Human Mouse Rat Fly
negative regulation of developmental process GO:0051093 65 0.144
response to stress GO:0006950 263 0.143
Zebrafish Mouse Rat
positive regulation of epithelial cell differentiation GO:0030858 2 0.142
Mouse Rat
formation of primary germ layer GO:0001704 62 0.141
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.141
positive regulation of muscle organ development GO:0048636 1 0.141
Mouse
ameboidal type cell migration GO:0001667 143 0.141
Human Fly
generation of neurons GO:0048699 385 0.140
positive regulation of stem cell proliferation GO:2000648 1 0.140
Rat
atrioventricular valve development GO:0003171 11 0.138
Human Mouse
apoptotic process GO:0006915 116 0.136
Human Mouse
skeletal muscle organ development GO:0060538 78 0.134
Human Mouse Fly
septum transversum development GO:0003343 4 0.132
positive regulation of cellular process GO:0048522 201 0.132
Human Zebrafish Mouse Rat Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.132
Zebrafish
cellular lipid catabolic process GO:0044242 3 0.130
epidermis development GO:0008544 48 0.126
Mouse
striated muscle cell development GO:0055002 108 0.123
Human
skeletal system morphogenesis GO:0048705 102 0.121
Zebrafish
response to external stimulus GO:0009605 264 0.120
Human Rat Fly
brain development GO:0007420 293 0.120
epidermal cell differentiation GO:0009913 36 0.119
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.119
Human Zebrafish Mouse Rat Fly
transmembrane transport GO:0055085 120 0.118
positive regulation of biological process GO:0048518 253 0.118
Human Zebrafish Mouse Rat Fly
endocardial cushion morphogenesis GO:0003203 3 0.115
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.114
Human Mouse Rat Fly
response to oxygen levels GO:0070482 25 0.114
Mouse
determination of heart left right asymmetry GO:0061371 117 0.112
Mouse
diencephalon development GO:0021536 58 0.111
Zebrafish
negative regulation of gene expression GO:0010629 65 0.110
Mouse Fly
system process GO:0003008 185 0.109
Zebrafish Fly
regulation of receptor mediated endocytosis GO:0048259 4 0.105
Zebrafish
muscle cell differentiation GO:0042692 139 0.103
Human Mouse Fly
neural retina development GO:0003407 49 0.103
neuroblast differentiation GO:0014016 1 0.103
Fly
intermediate mesoderm development GO:0048389 2 0.103
epithelial tube morphogenesis GO:0060562 148 0.101
Mouse Fly
regionalization GO:0003002 274 0.100
Zebrafish Mouse Fly
action potential GO:0001508 19 0.100
hemopoiesis GO:0030097 183 0.099
Mouse Fly
negative regulation of rna biosynthetic process GO:1902679 45 0.099
Mouse
nucleic acid templated transcription GO:0097659 181 0.099
Human Mouse Rat Fly
endocardial cushion development GO:0003197 6 0.099
Mouse
lipid catabolic process GO:0016042 4 0.097
photoreceptor cell differentiation GO:0046530 55 0.096
Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.096
Mouse
hematopoietic stem cell differentiation GO:0060218 20 0.095
cardiac muscle cell differentiation GO:0055007 30 0.095
regulation of developmental process GO:0050793 247 0.095
cell migration GO:0016477 237 0.095
Human Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.094
Human Mouse Rat Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.094
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.094
establishment of localization in cell GO:0051649 77 0.093
Mouse
camera type eye morphogenesis GO:0048593 108 0.093
neural crest cell migration GO:0001755 42 0.093
cellular response to hormone stimulus GO:0032870 39 0.093
Human
pharyngeal system development GO:0060037 18 0.092
regulation of vasculature development GO:1901342 33 0.091
Human
regulation of cell cycle GO:0051726 52 0.089
Worm Fly
positive regulation of multicellular organismal process GO:0051240 52 0.089
Human Zebrafish Mouse Rat
cell proliferation GO:0008283 80 0.087
Human Zebrafish Mouse Rat Worm Fly
myeloid cell differentiation GO:0030099 86 0.087
photoreceptor cell fate specification GO:0043704 1 0.086
astrocyte differentiation GO:0048708 1 0.086
Mouse Rat
regulation of heart rate GO:0002027 5 0.085
negative regulation of apoptotic process GO:0043066 55 0.084
Human
renal tubule development GO:0061326 5 0.082
Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.081
Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.081
Mouse
negative regulation of cell communication GO:0010648 96 0.080
Mouse
cell cell signaling GO:0007267 52 0.080
Worm Fly
regulation of cell migration GO:0030334 40 0.080
Human Mouse
negative regulation of biosynthetic process GO:0009890 55 0.080
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.079
Fly
mesenchymal cell proliferation GO:0010463 1 0.079
regulation of epithelial cell differentiation GO:0030856 7 0.079
Mouse Rat
transmission of nerve impulse GO:0019226 19 0.079
positive regulation of transport GO:0051050 2 0.078
mesenchyme development GO:0060485 127 0.078
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.077
Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.077
Mouse
positive regulation of endothelial cell differentiation GO:0045603 2 0.076
Rat
mesoderm formation GO:0001707 43 0.076
Zebrafish
gastrulation GO:0007369 208 0.074
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.073
Human Mouse Rat Fly
pectoral fin morphogenesis GO:0035138 29 0.073
nephron tubule morphogenesis GO:0072078 1 0.072
fin development GO:0033333 77 0.072
fin morphogenesis GO:0033334 53 0.072
muscle cell development GO:0055001 115 0.071
Human Mouse
nephron development GO:0072006 31 0.071
Mouse
cardiac conduction system development GO:0003161 1 0.071
Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.070
Fly
negative regulation of heart contraction GO:0045822 2 0.069
regulation of cardiac muscle tissue development GO:0055024 1 0.068
Mouse
somitogenesis GO:0001756 87 0.066
Zebrafish Mouse
regulation of cell proliferation GO:0042127 37 0.066
Human Mouse Rat Worm Fly
circulatory system process GO:0003013 87 0.066
Zebrafish
neural crest cell differentiation GO:0014033 72 0.065
cardiocyte differentiation GO:0035051 44 0.065
Mouse Fly
pectoral fin development GO:0033339 50 0.064
regulation of stem cell differentiation GO:2000736 4 0.064
Human Mouse Fly
cell part morphogenesis GO:0032990 246 0.064
mechanoreceptor differentiation GO:0042490 37 0.063
Mouse
cellular response to hypoxia GO:0071456 1 0.063
Mouse
cell proliferation involved in heart morphogenesis GO:0061323 2 0.063
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.062
response to light stimulus GO:0009416 46 0.062
programmed cell death GO:0012501 119 0.060
Human Mouse
neuron development GO:0048666 262 0.060
nephron epithelium development GO:0072009 16 0.060
Mouse
artery morphogenesis GO:0048844 14 0.060
Mouse
glial cell migration GO:0008347 3 0.060
Fly
proepicardium development GO:0003342 4 0.059
ventricular cardiac muscle tissue development GO:0003229 3 0.058
Mouse
neurological system process GO:0050877 62 0.057
Fly
artery development GO:0060840 22 0.057
Mouse
rhombomere boundary formation GO:0021654 10 0.057
negative regulation of neurogenesis GO:0050768 20 0.056
Zebrafish Mouse Rat Fly
cell migration involved in gastrulation GO:0042074 79 0.056
keratinocyte differentiation GO:0030216 0 0.056
Mouse
meiotic nuclear division GO:0007126 4 0.056
Worm
death GO:0016265 121 0.055
Human Mouse
regulation of molecular function GO:0065009 70 0.055
Mouse
negative regulation of cell death GO:0060548 60 0.054
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.054
Human Zebrafish Mouse Rat Fly
intracellular signal transduction GO:0035556 85 0.054
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.053
Human Mouse Rat Fly
single organism reproductive process GO:0044702 40 0.053
Mouse Rat Worm Fly
regulation of system process GO:0044057 40 0.053
enzyme linked receptor protein signaling pathway GO:0007167 106 0.052
Mouse
neuron projection morphogenesis GO:0048812 161 0.052
oligodendrocyte differentiation GO:0048709 23 0.052
Zebrafish Mouse Rat
negative regulation of cellular metabolic process GO:0031324 77 0.051
Mouse
cellular component biogenesis GO:0044085 178 0.051
Mouse Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.049
regulation of neurogenesis GO:0050767 87 0.049
Zebrafish Mouse Rat Fly
regulation of nervous system development GO:0051960 90 0.049
Zebrafish Mouse Rat Fly
heart valve development GO:0003170 14 0.048
Human Mouse
multicellular organismal signaling GO:0035637 22 0.048
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.048
pancreas development GO:0031016 84 0.048
Zebrafish
cognition GO:0050890 1 0.048
Fly
response to inorganic substance GO:0010035 38 0.047
response to peptide hormone GO:0043434 6 0.047
negative regulation of cell fate specification GO:0009996 11 0.046
negative regulation of rna metabolic process GO:0051253 48 0.045
Mouse
arterial endothelial cell differentiation GO:0060842 2 0.045
Mouse
gastrulation with mouth forming second GO:0001702 44 0.045
morphogenesis of an epithelial sheet GO:0002011 49 0.044
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.044
Human
cellular response to external stimulus GO:0071496 2 0.043
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.043
Mouse Rat
developmental growth GO:0048589 166 0.043
Zebrafish Mouse Rat
regulation of signal transduction GO:0009966 225 0.043
Mouse Fly
multicellular organism reproduction GO:0032504 35 0.043
Rat Worm Fly
embryonic pectoral fin morphogenesis GO:0035118 24 0.043
leukocyte differentiation GO:0002521 25 0.042
cellular localization GO:0051641 97 0.042
Mouse
negative regulation of programmed cell death GO:0043069 58 0.042
Human
protein metabolic process GO:0019538 183 0.042
Fly
hormone secretion GO:0046879 2 0.042
rhombomere development GO:0021546 19 0.042
heart valve morphogenesis GO:0003179 8 0.041
Human Mouse
peptide transport GO:0015833 1 0.041
regulation of cell death GO:0010941 103 0.041
Human Mouse
positive regulation of molecular function GO:0044093 33 0.041
regulation of cell development GO:0060284 100 0.040
Human Zebrafish Mouse Rat Fly
renal system vasculature development GO:0061437 2 0.040
Mouse
lipid metabolic process GO:0006629 52 0.040
negative regulation of signal transduction GO:0009968 94 0.040
Mouse
regulation of membrane potential GO:0042391 23 0.040
craniofacial suture morphogenesis GO:0097094 2 0.040
cellular lipid metabolic process GO:0044255 36 0.039
vasculogenesis GO:0001570 41 0.039
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.039
cranial nerve development GO:0021545 42 0.039
cardiac cell fate commitment GO:0060911 1 0.039
Fly
axon guidance GO:0007411 86 0.038
Fly
chemotaxis GO:0006935 104 0.038
Human Fly
morphogenesis of a branching epithelium GO:0061138 16 0.038
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.038
Fly
skeletal muscle tissue development GO:0007519 67 0.037
Human Mouse Fly
regulation of mesodermal cell fate specification GO:0042661 9 0.037
Zebrafish
otic vesicle development GO:0071599 42 0.036
notochord development GO:0030903 54 0.036
cellular response to growth factor stimulus GO:0071363 39 0.036
Human
neuron fate determination GO:0048664 2 0.036
cellular response to organic substance GO:0071310 105 0.035
Human
semicircular canal development GO:0060872 24 0.035
muscle structure development GO:0061061 196 0.035
Human Mouse Worm Fly
appendage development GO:0048736 80 0.035
Mouse Fly
mesodermal cell fate commitment GO:0001710 14 0.035
Zebrafish
pigment cell differentiation GO:0050931 38 0.035
cardiac muscle cell development GO:0055013 20 0.035
germ cell development GO:0007281 22 0.035
Fly
regulation of binding GO:0051098 3 0.034
phosphorus metabolic process GO:0006793 109 0.034
Fly
dorsal aorta morphogenesis GO:0035912 3 0.034
negative regulation of metabolic process GO:0009892 86 0.034
Mouse Fly
response to alkaloid GO:0043279 2 0.034
negative regulation of muscle cell differentiation GO:0051148 1 0.034
Human Mouse
regeneration GO:0031099 91 0.033
Zebrafish Rat
developmental programmed cell death GO:0010623 4 0.033
Mouse
localization of cell GO:0051674 244 0.033
Human Mouse Fly
nephron epithelium morphogenesis GO:0072088 1 0.033
cytoskeleton organization GO:0007010 96 0.032
Fly
camera type eye photoreceptor cell differentiation GO:0060219 19 0.032
neuron fate commitment GO:0048663 26 0.031
Mouse
negative regulation of nervous system development GO:0051961 22 0.031
Zebrafish Mouse Rat Fly
cranial suture morphogenesis GO:0060363 1 0.031
cellular response to organic cyclic compound GO:0071407 38 0.031
regulation of mesenchymal cell proliferation GO:0010464 1 0.031
branching morphogenesis of an epithelial tube GO:0048754 15 0.031
Mouse
protein localization GO:0008104 40 0.031
Mouse
response to other organism GO:0051707 97 0.031
Rat Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.031
positive regulation of developmental process GO:0051094 50 0.031
Human Zebrafish Mouse Rat
cellular response to oxygen containing compound GO:1901701 20 0.030
pigmentation GO:0043473 85 0.030
gland development GO:0048732 143 0.030
Zebrafish Mouse Fly
positive regulation of cell differentiation GO:0045597 30 0.029
Human Zebrafish Mouse Rat
semicircular canal morphogenesis GO:0048752 18 0.029
cell death GO:0008219 121 0.029
Human Mouse
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.029
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.029
Mouse
growth GO:0040007 174 0.029
Zebrafish Mouse Rat Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.029
Mouse
atrial ventricular junction remodeling GO:0003294 2 0.029
regulation of chemotaxis GO:0050920 18 0.028
Human
regulation of heart growth GO:0060420 2 0.028
Mouse
protein modification process GO:0036211 100 0.028
Fly
multicellular organismal macromolecule metabolic process GO:0044259 2 0.028
regulation of locomotion GO:0040012 55 0.028
Human Mouse
endocardium formation GO:0060214 1 0.028
regulation of protein metabolic process GO:0051246 56 0.028
single organism organelle organization GO:1902589 199 0.028
Fly
regulation of cell fate specification GO:0042659 20 0.028
Zebrafish Fly
regulation of striated muscle tissue development GO:0016202 6 0.028
Human Mouse
axonogenesis GO:0007409 152 0.028
tissue regeneration GO:0042246 74 0.028
Zebrafish Rat
multicellular organismal homeostasis GO:0048871 29 0.028
appendage morphogenesis GO:0035107 56 0.028
Mouse Fly
regulation of cellular component organization GO:0051128 86 0.027
Human Zebrafish Mouse Worm Fly
pharyngeal muscle development GO:0043282 4 0.027
Worm
endocrine system development GO:0035270 65 0.027
otic vesicle morphogenesis GO:0071600 34 0.027
hormone biosynthetic process GO:0042446 3 0.027
regulation of carbohydrate biosynthetic process GO:0043255 1 0.027
cell cycle GO:0007049 93 0.027
Worm Fly
i kappab kinase nf kappab signaling GO:0007249 4 0.027
Fly
heart formation GO:0060914 13 0.027
Rat
lipid storage GO:0019915 1 0.027
somite development GO:0061053 96 0.027
Zebrafish Mouse
swim bladder maturation GO:0048796 5 0.027
regulation of biological quality GO:0065008 263 0.027
Zebrafish Fly
regulation of cell activation GO:0050865 1 0.026
regulation of neural precursor cell proliferation GO:2000177 3 0.026
Rat
dorsal aorta development GO:0035907 4 0.026
epithelial cell migration GO:0010631 25 0.026
Human Fly
mitotic cell cycle GO:0000278 64 0.026
Fly
regulation of reproductive process GO:2000241 4 0.026
Mouse
neuronal action potential GO:0019228 18 0.026
mesodermal cell differentiation GO:0048333 21 0.026
Zebrafish
regulation of catalytic activity GO:0050790 55 0.026
Mouse
water homeostasis GO:0030104 4 0.026
response to peptide GO:1901652 6 0.025
Mouse
central nervous system neuron differentiation GO:0021953 74 0.025
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.025
Zebrafish Fly
outflow tract morphogenesis GO:0003151 1 0.025
regulation of cellular component biogenesis GO:0044087 12 0.025
Mouse Fly
kidney development GO:0001822 92 0.025
Zebrafish Mouse
retinal cone cell differentiation GO:0042670 12 0.024
cardiac muscle cell proliferation GO:0060038 5 0.024
Mouse
negative regulation of mesodermal cell fate specification GO:0042662 3 0.024
nerve development GO:0021675 45 0.024
myotube differentiation GO:0014902 45 0.024
Human Mouse
somatic stem cell maintenance GO:0035019 1 0.024
Zebrafish
peripheral nervous system development GO:0007422 55 0.024
kupffer s vesicle development GO:0070121 50 0.023
hormone transport GO:0009914 2 0.023
response to growth factor GO:0070848 39 0.023
Human
cellular response to decreased oxygen levels GO:0036294 1 0.023
Mouse
mesoderm morphogenesis GO:0048332 51 0.023
Zebrafish
blood vessel endothelial cell migration GO:0043534 18 0.023
Human
cardiogenic plate morphogenesis GO:0003142 1 0.023
tissue remodeling GO:0048771 4 0.022
otolith development GO:0048840 32 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
forebrain development GO:0030900 96 0.022
Zebrafish Mouse
cellular response to peptide hormone stimulus GO:0071375 5 0.022
embryonic hemopoiesis GO:0035162 53 0.022
Fly
lipid oxidation GO:0034440 1 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
Rat Worm Fly
maintenance of location GO:0051235 4 0.022
response to lipid GO:0033993 60 0.022
Rat
kidney vasculature development GO:0061440 2 0.022
Mouse
multi organism process GO:0051704 134 0.022
Rat Worm Fly
cell adhesion GO:0007155 40 0.021
Human Fly
oocyte maturation GO:0001556 4 0.021
negative regulation of cell motility GO:2000146 17 0.021
Human
small molecule metabolic process GO:0044281 77 0.021
regulation of bone mineralization GO:0030500 2 0.021
regulation of muscle organ development GO:0048634 9 0.021
Human Mouse
regulation of embryonic development GO:0045995 47 0.021
Zebrafish Mouse
connective tissue development GO:0061448 99 0.021
Zebrafish Mouse
positive regulation of intracellular signal transduction GO:1902533 15 0.021
Mouse
myeloid cell homeostasis GO:0002262 56 0.021
taxis GO:0042330 109 0.021
Human Fly
regulation of angiogenesis GO:0045765 26 0.021
Human
epithelial cell fate commitment GO:0072148 11 0.021
Mouse
somatic muscle development GO:0007525 4 0.021
hair cell differentiation GO:0035315 32 0.021
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
floor plate development GO:0033504 15 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.020

notch1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.568
Human
nervous system disease DOID:863 0 0.087
musculoskeletal system disease DOID:17 0 0.061
disease of metabolism DOID:0014667 0 0.032
cardiovascular system disease DOID:1287 0 0.023
Human
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
heart disease DOID:114 0 0.021
Human
cardiomyopathy DOID:0050700 0 0.021
muscle tissue disease DOID:66 0 0.021