Danio rerio

14 known processes

npm1

nucleophosmin 1

(Aliases: npm1a,sb:cb487)

npm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribosome biogenesis GO:0042254 9 0.922
Mouse
nuclear export GO:0051168 1 0.888
Mouse
ribonucleoprotein complex biogenesis GO:0022613 13 0.847
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.806
hemopoiesis GO:0030097 183 0.766
cellular nitrogen compound metabolic process GO:0034641 290 0.730
Human Mouse
organelle organization GO:0006996 227 0.687
Human Mouse
immune system development GO:0002520 191 0.630
cellular macromolecule metabolic process GO:0044260 391 0.629
Human Mouse
immune system process GO:0002376 241 0.585
rna processing GO:0006396 25 0.561
Mouse
ribosomal small subunit biogenesis GO:0042274 2 0.553
Mouse
nitrogen compound metabolic process GO:0006807 319 0.530
Human Mouse
heterocycle metabolic process GO:0046483 290 0.524
Human Mouse
nuclear transport GO:0051169 4 0.499
Human Mouse
positive regulation of translation GO:0045727 1 0.482
Human
microtubule organizing center organization GO:0031023 1 0.416
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.404
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.375
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.336
Human Mouse
rna metabolic process GO:0016070 219 0.334
Human Mouse
gene expression GO:0010467 252 0.325
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.251
Human
establishment of localization GO:0051234 244 0.244
Human Mouse
regulation of biological quality GO:0065008 263 0.238
Mouse
ncrna metabolic process GO:0034660 12 0.229
centrosome cycle GO:0007098 1 0.219
Human Mouse
aromatic compound biosynthetic process GO:0019438 217 0.195
Human
single organism organelle organization GO:1902589 199 0.187
Human Mouse
apoptotic process GO:0006915 116 0.177
Human
regulation of deoxyribonuclease activity GO:0032070 1 0.170
Human
macromolecule biosynthetic process GO:0009059 227 0.163
Human
cellular localization GO:0051641 97 0.156
Human Mouse
homeostatic process GO:0042592 142 0.143
Mouse
cell migration GO:0016477 237 0.138
cell proliferation GO:0008283 80 0.127
Human Mouse
cellular component biogenesis GO:0044085 178 0.123
Human Mouse
organelle assembly GO:0070925 110 0.121
Human
regulation of macromolecule metabolic process GO:0060255 317 0.119
Human Mouse
response to chemical GO:0042221 320 0.116
Human
larval development GO:0002164 2 0.116
aging GO:0007568 2 0.113
Human
cell cycle GO:0007049 93 0.109
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.106
Mouse
regulation of mrna processing GO:0050684 3 0.104
Mouse
regulation of multicellular organism growth GO:0040014 4 0.100
cell motility GO:0048870 244 0.098
maturation of ssu rrna GO:0030490 1 0.093
rrna metabolic process GO:0016072 8 0.091
negative regulation of metabolic process GO:0009892 86 0.091
Human Mouse
cellular protein metabolic process GO:0044267 129 0.090
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.090
Human
cell activation GO:0001775 16 0.088
organic substance biosynthetic process GO:1901576 289 0.088
Human
regulation of mrna splicing via spliceosome GO:0048024 3 0.087
Mouse
maintenance of location GO:0051235 4 0.087
protein modification process GO:0036211 100 0.084
Human Mouse
death GO:0016265 121 0.083
Human
programmed cell death GO:0012501 119 0.082
Human
locomotion GO:0040011 313 0.081
centrosome organization GO:0051297 1 0.079
Human Mouse
digestive system development GO:0055123 289 0.078
chromosome organization GO:0051276 31 0.074
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.071
Mouse
macromolecule modification GO:0043412 111 0.071
Human Mouse
protein methylation GO:0006479 13 0.071
cellular component movement GO:0006928 335 0.068
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.068
Human
nucleocytoplasmic transport GO:0006913 4 0.068
Human Mouse
er nucleus signaling pathway GO:0006984 2 0.066
nucleobase containing compound metabolic process GO:0006139 274 0.065
Human Mouse
mrna metabolic process GO:0016071 20 0.063
Mouse
growth GO:0040007 174 0.063
Mouse
translational initiation GO:0006413 3 0.063
cell death GO:0008219 121 0.063
Human
regulation of response to stimulus GO:0048583 269 0.060
Human Mouse
regulation of translational initiation GO:0006446 1 0.060
Human
response to stress GO:0006950 263 0.059
Human Mouse
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.058
organelle localization GO:0051640 49 0.058
Mouse
negative regulation of biological process GO:0048519 304 0.056
Human Mouse
tube morphogenesis GO:0035239 349 0.055
cell aging GO:0007569 2 0.054
Human
response to external biotic stimulus GO:0043207 97 0.054
cellular response to dsrna GO:0071359 1 0.054
Human
chromatin organization GO:0006325 22 0.053
Human
protein metabolic process GO:0019538 183 0.049
Human Mouse
rrna processing GO:0006364 7 0.049
embryo development ending in birth or egg hatching GO:0009792 271 0.049
establishment of localization in cell GO:0051649 77 0.049
Human Mouse
cellular response to stress GO:0033554 62 0.049
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.049
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 22 0.048
Human Mouse
dna metabolic process GO:0006259 27 0.048
Human
localization of cell GO:0051674 244 0.047
muscle structure development GO:0061061 196 0.045
macromolecular complex subunit organization GO:0043933 74 0.045
Human
cellular response to organic substance GO:0071310 105 0.043
Human
regulation of developmental process GO:0050793 247 0.043
Mouse
positive regulation of cellular process GO:0048522 201 0.043
Human Mouse
response to organic substance GO:0010033 153 0.042
Human
biosynthetic process GO:0009058 294 0.041
Human Mouse
positive regulation of biosynthetic process GO:0009891 68 0.041
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.038
regulation of cellular metabolic process GO:0031323 320 0.037
Human Mouse
multi organism process GO:0051704 134 0.037
ncrna processing GO:0034470 8 0.037
nucleic acid templated transcription GO:0097659 181 0.036
Human
rna biosynthetic process GO:0032774 181 0.036
Human
spindle assembly GO:0051225 2 0.036
positive regulation of cellular metabolic process GO:0031325 94 0.036
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.035
Human Mouse
transport GO:0006810 220 0.034
Human Mouse
regulation of dna catabolic process GO:1903624 1 0.033
Human
microtubule cytoskeleton organization GO:0000226 33 0.033
Human Mouse
cytoskeleton organization GO:0007010 96 0.033
Human Mouse
regulation of signaling GO:0023051 235 0.032
Mouse
developmental process involved in reproduction GO:0003006 27 0.031
cellular response to chemical stimulus GO:0070887 157 0.030
Human
embryonic cranial skeleton morphogenesis GO:0048701 90 0.029
digestive tract development GO:0048565 265 0.028
cell cycle process GO:0022402 53 0.028
Human Mouse
multicellular organism growth GO:0035264 4 0.028
cell growth GO:0016049 57 0.027
Mouse
regulation of gene expression GO:0010468 265 0.027
Human Mouse
single organism metabolic process GO:0044710 217 0.027
Human
determination of heart left right asymmetry GO:0061371 117 0.027
microtubule based process GO:0007017 60 0.027
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
Human
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.027
Mouse
cellular protein modification process GO:0006464 100 0.026
Human Mouse
intracellular transport GO:0046907 32 0.026
Human Mouse
establishment of organelle localization GO:0051656 45 0.026
Mouse
morphogenesis of an epithelium GO:0002009 333 0.025
b cell activation GO:0042113 2 0.025
transcription dna templated GO:0006351 181 0.025
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.025
Human
regulation of multicellular organismal process GO:0051239 277 0.025
regulation of transcription dna templated GO:0006355 213 0.025
Human
negative regulation of cellular metabolic process GO:0031324 77 0.025
Human Mouse
negative regulation of cellular process GO:0048523 283 0.025
Human Mouse
protein localization GO:0008104 40 0.025
Human Mouse
reproductive process GO:0022414 40 0.024
regulation of cellular protein metabolic process GO:0032268 52 0.023
Human Mouse
centrosome duplication GO:0051298 1 0.023
Human Mouse
cellular biosynthetic process GO:0044249 286 0.023
Human Mouse
mononuclear cell proliferation GO:0032943 1 0.023
regulation of cell communication GO:0010646 232 0.022
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
Human
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.022
regulation of cell death GO:0010941 103 0.021
Human
intracellular signal transduction GO:0035556 85 0.021
Mouse
lipid storage GO:0019915 1 0.021
single organism transport GO:0044765 206 0.021
Mouse
hematopoietic progenitor cell differentiation GO:0002244 23 0.021
stem cell development GO:0048864 82 0.020
Mouse
positive regulation of biological process GO:0048518 253 0.020
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.019
Human
heterocycle biosynthetic process GO:0018130 215 0.019
Human
macromolecule methylation GO:0043414 19 0.019
regulation of cell cycle GO:0051726 52 0.019
Human Mouse
amine metabolic process GO:0009308 2 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
response to biotic stimulus GO:0009607 97 0.018
stem cell differentiation GO:0048863 117 0.018
Mouse
dna catabolic process GO:0006308 1 0.017
Human
multicellular organism reproduction GO:0032504 35 0.017
single organism localization GO:1902578 225 0.017
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
Human Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.016
regulation of tube size GO:0035150 2 0.016
gamete generation GO:0007276 33 0.016
regulation of nuclease activity GO:0032069 1 0.016
Human
regulation of signal transduction GO:0009966 225 0.016
Mouse
negative regulation of programmed cell death GO:0043069 58 0.016
Human
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.015
Mouse
negative regulation of mrna metabolic process GO:1903312 3 0.015
Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
determination of left right symmetry GO:0007368 179 0.015
developmental growth GO:0048589 166 0.015
response to virus GO:0009615 21 0.015
regulation of metabolic process GO:0019222 359 0.015
Human Mouse
single organism intracellular transport GO:1902582 25 0.015
Mouse
regulation of mrna metabolic process GO:1903311 6 0.015
Mouse
regulation of organelle organization GO:0033043 29 0.014
Human Mouse
histone modification GO:0016570 20 0.014
nucleoside biosynthetic process GO:0009163 2 0.014
generation of neurons GO:0048699 385 0.014
embryonic heart tube development GO:0035050 133 0.014
posttranscriptional gene silencing GO:0016441 3 0.014
regulation of apoptotic process GO:0042981 98 0.014
Human
protein alkylation GO:0008213 13 0.014
ribosome assembly GO:0042255 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
rna splicing via transesterification reactions GO:0000375 10 0.013
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of programmed cell death GO:0043067 101 0.013
Human
leukocyte proliferation GO:0070661 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
Human Mouse
pyrimidine containing compound biosynthetic process GO:0072528 2 0.013
negative regulation of gene expression GO:0010629 65 0.013
Mouse
regulation of signal transduction by p53 class mediator GO:1901796 9 0.013
Mouse
regulation of growth GO:0040008 42 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
negative regulation of cell death GO:0060548 60 0.012
Human
gastrulation GO:0007369 208 0.012
response to endogenous stimulus GO:0009719 83 0.012
positive regulation of transport GO:0051050 2 0.012
organic substance catabolic process GO:1901575 28 0.012
Human
macromolecule localization GO:0033036 54 0.012
Human Mouse
bicarbonate transport GO:0015701 4 0.012
signal transduction by p53 class mediator GO:0072331 13 0.012
Mouse
signal transduction GO:0007165 455 0.012
Mouse
regulation of rna metabolic process GO:0051252 224 0.011
Human Mouse
rna export from nucleus GO:0006405 1 0.011
Mouse
reciprocal meiotic recombination GO:0007131 1 0.011
regulation of cell differentiation GO:0045595 142 0.011
Mouse
small molecule metabolic process GO:0044281 77 0.011
negative regulation of mrna processing GO:0050686 1 0.011
Mouse
positive regulation of developmental process GO:0051094 50 0.011
embryonic pattern specification GO:0009880 44 0.011
regulation of cell activation GO:0050865 1 0.011
response to other organism GO:0051707 97 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
mitotic cell cycle GO:0000278 64 0.011
protein acetylation GO:0006473 2 0.011
ribonucleoside biosynthetic process GO:0042455 2 0.010
exocrine pancreas development GO:0031017 28 0.010
rna modification GO:0009451 2 0.010
transmembrane transport GO:0055085 120 0.010
zymogen activation GO:0031638 3 0.010
digestive tract morphogenesis GO:0048546 231 0.010
regulation of cardiac muscle contraction GO:0055117 2 0.010
heart looping GO:0001947 94 0.010

npm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.108
musculoskeletal system disease DOID:17 0 0.018
sensory system disease DOID:0050155 0 0.011
nervous system disease DOID:863 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
Human