Danio rerio

75 known processes

nr1i2

nuclear receptor subfamily 1, group I, member 2

(Aliases: PXR)

nr1i2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.591
head development GO:0060322 303 0.467
nitrogen compound metabolic process GO:0006807 319 0.371
regulation of primary metabolic process GO:0080090 311 0.362
cellular biosynthetic process GO:0044249 286 0.320
signal transduction GO:0007165 455 0.275
cellular macromolecule metabolic process GO:0044260 391 0.272
small molecule metabolic process GO:0044281 77 0.270
endocrine system development GO:0035270 65 0.262
macromolecule biosynthetic process GO:0009059 227 0.258
brain development GO:0007420 293 0.249
negative regulation of cellular process GO:0048523 283 0.243
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.223
organic cyclic compound metabolic process GO:1901360 301 0.223
generation of neurons GO:0048699 385 0.222
rna biosynthetic process GO:0032774 181 0.218
regulation of metabolic process GO:0019222 359 0.216
regulation of cellular metabolic process GO:0031323 320 0.212
regulation of macromolecule metabolic process GO:0060255 317 0.211
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.202
regulation of rna metabolic process GO:0051252 224 0.197
regulation of transcription dna templated GO:0006355 213 0.196
gene expression GO:0010467 252 0.190
oxoacid metabolic process GO:0043436 31 0.188
locomotion GO:0040011 313 0.184
ameboidal type cell migration GO:0001667 143 0.182
aromatic compound biosynthetic process GO:0019438 217 0.179
nucleic acid templated transcription GO:0097659 181 0.177
regulation of biosynthetic process GO:0009889 250 0.174
cellular nitrogen compound metabolic process GO:0034641 290 0.171
cellular aromatic compound metabolic process GO:0006725 295 0.162
morphogenesis of an epithelium GO:0002009 333 0.161
cellular carbohydrate metabolic process GO:0044262 4 0.159
Fly
diencephalon development GO:0021536 58 0.156
aging GO:0007568 2 0.147
regulation of macromolecule biosynthetic process GO:0010556 225 0.146
biosynthetic process GO:0009058 294 0.143
heterocycle biosynthetic process GO:0018130 215 0.142
organic substance biosynthetic process GO:1901576 289 0.141
gland development GO:0048732 143 0.137
cellular nitrogen compound biosynthetic process GO:0044271 218 0.132
organic cyclic compound biosynthetic process GO:1901362 223 0.131
cellular macromolecule biosynthetic process GO:0034645 224 0.128
regulation of nucleic acid templated transcription GO:1903506 213 0.127
positive regulation of biosynthetic process GO:0009891 68 0.126
Human
nuclear transport GO:0051169 4 0.125
protein import into nucleus GO:0006606 3 0.118
establishment of protein localization to organelle GO:0072594 4 0.118
protein import GO:0017038 3 0.117
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.107
heterocycle metabolic process GO:0046483 290 0.103
negative regulation of biological process GO:0048519 304 0.102
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.101
rna metabolic process GO:0016070 219 0.101
nucleobase containing compound biosynthetic process GO:0034654 205 0.100
nucleic acid metabolic process GO:0090304 244 0.092
regulation of gene expression GO:0010468 265 0.089
regulation of signaling GO:0023051 235 0.088
endocrine process GO:0050886 2 0.088
multicellular organism growth GO:0035264 4 0.087
regionalization GO:0003002 274 0.086
positive regulation of metabolic process GO:0009893 108 0.086
Human Mouse
localization of cell GO:0051674 244 0.083
nucleobase containing compound metabolic process GO:0006139 274 0.082
skeletal system development GO:0001501 181 0.082
connective tissue development GO:0061448 99 0.079
regulation of signal transduction GO:0009966 225 0.078
organic acid metabolic process GO:0006082 31 0.077
protein targeting to nucleus GO:0044744 3 0.077
regulation of carbohydrate metabolic process GO:0006109 4 0.076
Fly
cell surface receptor signaling pathway GO:0007166 325 0.076
organonitrogen compound metabolic process GO:1901564 74 0.076
cartilage development GO:0051216 96 0.075
nuclear import GO:0051170 3 0.074
cell fate commitment GO:0045165 99 0.074
axon ensheathment in central nervous system GO:0032291 2 0.074
single organism nuclear import GO:1902593 3 0.074
transcription from rna polymerase ii promoter GO:0006366 80 0.073
single organism metabolic process GO:0044710 217 0.073
Fly
sensory organ development GO:0007423 393 0.073
apoptotic process GO:0006915 116 0.070
epidermis development GO:0008544 48 0.069
energy reserve metabolic process GO:0006112 2 0.069
Fly
protein localization to nucleus GO:0034504 3 0.069
lipid catabolic process GO:0016042 4 0.068
programmed cell death GO:0012501 119 0.068
dorsal ventral pattern formation GO:0009953 125 0.067
response to stress GO:0006950 263 0.067
Fly
alcohol biosynthetic process GO:0046165 2 0.066
regulation of multicellular organism growth GO:0040014 4 0.065
carboxylic acid metabolic process GO:0019752 22 0.063
lipid storage GO:0019915 1 0.063
cellular modified amino acid metabolic process GO:0006575 3 0.063
forebrain development GO:0030900 96 0.061
positive regulation of biological process GO:0048518 253 0.060
Human Mouse
organophosphate biosynthetic process GO:0090407 23 0.060
hindbrain development GO:0030902 91 0.059
single organism biosynthetic process GO:0044711 71 0.058
blood circulation GO:0008015 87 0.058
digestive tract development GO:0048565 265 0.058
response to vitamin GO:0033273 3 0.058
blood vessel development GO:0001568 246 0.058
mesenchymal cell development GO:0014031 78 0.058
positive regulation of transport GO:0051050 2 0.057
regulation of multicellular organismal process GO:0051239 277 0.057
cell morphogenesis GO:0000902 289 0.057
positive regulation of rna metabolic process GO:0051254 59 0.055
Human
nucleocytoplasmic transport GO:0006913 4 0.054
response to nutrient GO:0007584 3 0.054
cellular amino acid metabolic process GO:0006520 7 0.054
single organism localization GO:1902578 225 0.054
Human
positive regulation of nucleic acid templated transcription GO:1903508 57 0.054
Human
retinoic acid receptor signaling pathway GO:0048384 16 0.052
regulation of establishment of protein localization GO:0070201 4 0.052
regulation of biological quality GO:0065008 263 0.051
Zebrafish Fly
regulation of protein transport GO:0051223 3 0.050
g protein coupled receptor signaling pathway GO:0007186 74 0.049
digestive system development GO:0055123 289 0.049
fatty acid transport GO:0015908 1 0.049
response to chemical GO:0042221 320 0.049
regulation of hormone levels GO:0010817 21 0.048
hormone transport GO:0009914 2 0.048
epiboly GO:0090504 41 0.047
circadian sleep wake cycle sleep GO:0050802 1 0.047
positive regulation of cellular biosynthetic process GO:0031328 68 0.045
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.045
camera type eye development GO:0043010 222 0.045
eye morphogenesis GO:0048592 144 0.044
epithelial cell differentiation GO:0030855 116 0.044
hormone mediated signaling pathway GO:0009755 9 0.044
regulation of cell communication GO:0010646 232 0.044
vasculature development GO:0001944 278 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.042
Human
cell death GO:0008219 121 0.041
response to external stimulus GO:0009605 264 0.041
Fly
neural crest cell migration GO:0001755 42 0.041
neural crest cell development GO:0014032 62 0.041
cell proliferation GO:0008283 80 0.041
regulation of neural precursor cell proliferation GO:2000177 3 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
digestive tract morphogenesis GO:0048546 231 0.040
cell motility GO:0048870 244 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
regulation of cell death GO:0010941 103 0.038
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
Human Mouse
lymphangiogenesis GO:0001946 25 0.037
germ line stem cell maintenance GO:0030718 2 0.037
positive regulation of catabolic process GO:0009896 4 0.037
inner ear development GO:0048839 126 0.037
maintenance of location GO:0051235 4 0.037
cognition GO:0050890 1 0.037
positive regulation of gene expression GO:0010628 71 0.036
Human Mouse
regulation of muscle contraction GO:0006937 3 0.036
neural crest cell differentiation GO:0014033 72 0.036
negative regulation of rna metabolic process GO:0051253 48 0.036
Human Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
intracellular receptor signaling pathway GO:0030522 30 0.036
hormone secretion GO:0046879 2 0.035
sensory perception of pain GO:0019233 1 0.035
cellular component movement GO:0006928 335 0.035
embryonic organ morphogenesis GO:0048562 274 0.035
negative regulation of cellular metabolic process GO:0031324 77 0.035
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.034
Human
cell morphogenesis involved in differentiation GO:0000904 195 0.034
regulation of protein targeting GO:1903533 2 0.034
morphogenesis of an epithelial sheet GO:0002011 49 0.034
neuron differentiation GO:0030182 353 0.034
pigmentation GO:0043473 85 0.034
hormone metabolic process GO:0042445 19 0.033
b cell activation GO:0042113 2 0.033
cellular response to external stimulus GO:0071496 2 0.033
regulation of metal ion transport GO:0010959 4 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
endoderm development GO:0007492 49 0.032
response to wounding GO:0009611 116 0.032
cell fate specification GO:0001708 68 0.032
otic vesicle development GO:0071599 42 0.032
circulatory system process GO:0003013 87 0.032
regulation of tube size GO:0035150 2 0.032
transcription dna templated GO:0006351 181 0.032
lipid metabolic process GO:0006629 52 0.031
single organism carbohydrate metabolic process GO:0044723 12 0.031
Fly
steroid hormone mediated signaling pathway GO:0043401 9 0.031
regulation of epithelial cell proliferation GO:0050678 3 0.031
cell migration GO:0016477 237 0.031
embryonic organ development GO:0048568 381 0.031
positive regulation of cell cycle GO:0045787 3 0.030
multicellular organismal metabolic process GO:0044236 2 0.030
determination of bilateral symmetry GO:0009855 204 0.030
gtp catabolic process GO:0006184 2 0.030
pituitary gland development GO:0021983 16 0.030
regulation of protein localization to nucleus GO:1900180 2 0.030
skin development GO:0043588 54 0.029
catechol containing compound metabolic process GO:0009712 2 0.029
negative regulation of rna biosynthetic process GO:1902679 45 0.029
Human Mouse
peptide transport GO:0015833 1 0.029
neuroblast proliferation GO:0007405 2 0.029
nerve development GO:0021675 45 0.029
cellular response to oxygen levels GO:0071453 1 0.029
retina development in camera type eye GO:0060041 146 0.028
pancreas development GO:0031016 84 0.028
organelle organization GO:0006996 227 0.028
death GO:0016265 121 0.028
larval development GO:0002164 2 0.028
regulation of protein import into nucleus GO:0042306 2 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
Human
polyol metabolic process GO:0019751 1 0.028
sensory organ morphogenesis GO:0090596 200 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
Human
stem cell fate commitment GO:0048865 1 0.028
regulation of intracellular protein transport GO:0033157 3 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
regulation of locomotion GO:0040012 55 0.027
eye development GO:0001654 277 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.027
Human Mouse
ear development GO:0043583 127 0.027
stem cell proliferation GO:0072089 4 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
neuron development GO:0048666 262 0.027
negative regulation of metabolic process GO:0009892 86 0.027
Human Mouse
mitochondrion organization GO:0007005 4 0.026
response to extracellular stimulus GO:0009991 10 0.026
Fly
regulation of developmental process GO:0050793 247 0.026
system process GO:0003008 185 0.026
tissue regeneration GO:0042246 74 0.026
macromolecule modification GO:0043412 111 0.026
negative regulation of gene expression GO:0010629 65 0.026
Human Mouse
wound healing GO:0042060 90 0.026
vascular process in circulatory system GO:0003018 6 0.026
positive regulation of blood circulation GO:1903524 2 0.025
action potential GO:0001508 19 0.025
stem cell development GO:0048864 82 0.025
regulation of apoptotic process GO:0042981 98 0.025
homeostatic process GO:0042592 142 0.025
Zebrafish Fly
reactive nitrogen species metabolic process GO:2001057 0 0.025
regulation of sodium ion transport GO:0002028 2 0.025
immune system development GO:0002520 191 0.025
epidermal cell fate specification GO:0009957 4 0.024
reactive oxygen species biosynthetic process GO:1903409 1 0.024
cell projection morphogenesis GO:0048858 244 0.024
hepaticobiliary system development GO:0061008 98 0.024
embryonic limb morphogenesis GO:0030326 2 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
adenohypophysis development GO:0021984 15 0.024
regulation of intracellular signal transduction GO:1902531 57 0.024
regulation of blood vessel size GO:0050880 2 0.024
phosphorus metabolic process GO:0006793 109 0.024
cell part morphogenesis GO:0032990 246 0.024
meiotic nuclear division GO:0007126 4 0.024
negative regulation of nucleic acid templated transcription GO:1903507 45 0.024
Human Mouse
tube morphogenesis GO:0035239 349 0.023
cellular localization GO:0051641 97 0.023
regulation of binding GO:0051098 3 0.023
response to alkaloid GO:0043279 2 0.023
response to organic substance GO:0010033 153 0.023
small molecule catabolic process GO:0044282 3 0.023
regulation of programmed cell death GO:0043067 101 0.023
immune system process GO:0002376 241 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
Human Mouse
specification of symmetry GO:0009799 204 0.023
ventral spinal cord development GO:0021517 35 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
sleep GO:0030431 1 0.023
ear morphogenesis GO:0042471 64 0.023
skeletal system morphogenesis GO:0048705 102 0.023
axonogenesis GO:0007409 152 0.022
regulation of calcium ion transport GO:0051924 2 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
glial cell migration GO:0008347 3 0.022
small molecule biosynthetic process GO:0044283 16 0.022
neuron projection guidance GO:0097485 86 0.022
cellular component disassembly GO:0022411 1 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.021
astrocyte differentiation GO:0048708 1 0.021
regulation of circadian rhythm GO:0042752 4 0.021
carbohydrate metabolic process GO:0005975 12 0.021
Fly
cranial nerve development GO:0021545 42 0.021
mesoderm development GO:0007498 88 0.021
central nervous system neuron differentiation GO:0021953 74 0.021
regulation of fatty acid metabolic process GO:0019217 1 0.021
camera type eye morphogenesis GO:0048593 108 0.021
regulation of oligodendrocyte differentiation GO:0048713 1 0.021
establishment of localization GO:0051234 244 0.020
Human
fertilization GO:0009566 3 0.020
startle response GO:0001964 4 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
compound eye development GO:0048749 2 0.020
regulation of response to stimulus GO:0048583 269 0.020
transport GO:0006810 220 0.020
Human
response to food GO:0032094 1 0.020
mononuclear cell proliferation GO:0032943 1 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.019
Human Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
pectoral fin development GO:0033339 50 0.019
anterior posterior pattern specification GO:0009952 152 0.019
cellular ketone metabolic process GO:0042180 11 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of molecular function GO:0065009 70 0.019
long chain fatty acid transport GO:0015909 1 0.019
keratinocyte differentiation GO:0030216 0 0.019
cellular response to organic substance GO:0071310 105 0.019
central nervous system myelin formation GO:0032289 1 0.019
developmental growth GO:0048589 166 0.019
defense response to fungus GO:0050832 2 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.018
mesenchyme development GO:0060485 127 0.018
cellular amine metabolic process GO:0044106 2 0.018
regulation of hormone secretion GO:0046883 2 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
reactive oxygen species metabolic process GO:0072593 6 0.018
response to hexose GO:0009746 3 0.018
embryonic skeletal system development GO:0048706 97 0.018
negative regulation of protein transport GO:0051224 3 0.018
b cell differentiation GO:0030183 1 0.018
macromolecular complex disassembly GO:0032984 1 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
Human Mouse
female gonad development GO:0008585 4 0.018
positive regulation of cell activation GO:0050867 1 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
gtp metabolic process GO:0046039 4 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
establishment of localization in cell GO:0051649 77 0.018
positive regulation of lipid catabolic process GO:0050996 1 0.018
sympathetic nervous system development GO:0048485 3 0.018
exocytosis GO:0006887 1 0.018
negative regulation of dna replication GO:0008156 2 0.018
positive regulation of immune effector process GO:0002699 3 0.017
amine metabolic process GO:0009308 2 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
Human
smooth muscle contraction GO:0006939 2 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of cytokine production GO:0001817 3 0.017
response to decreased oxygen levels GO:0036293 25 0.017
inner ear morphogenesis GO:0042472 63 0.017
regulation of organ growth GO:0046620 3 0.017
cellular component morphogenesis GO:0032989 336 0.017
central nervous system myelination GO:0022010 2 0.017
regulation of inflammatory response GO:0050727 2 0.017
lipid homeostasis GO:0055088 3 0.017
Zebrafish Fly
cellular protein metabolic process GO:0044267 129 0.017
monoamine transport GO:0015844 1 0.016
cellular response to hypoxia GO:0071456 1 0.016
organ regeneration GO:0031100 1 0.016
embryonic heart tube development GO:0035050 133 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
Human Mouse
phenol containing compound metabolic process GO:0018958 5 0.016
neuron projection morphogenesis GO:0048812 161 0.016
carboxylic acid catabolic process GO:0046395 3 0.016
chemosensory behavior GO:0007635 1 0.016
response to monosaccharide GO:0034284 3 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of blood pressure GO:0008217 1 0.016
floor plate development GO:0033504 15 0.016
response to nutrient levels GO:0031667 10 0.016
Fly
single organism transport GO:0044765 206 0.016
Human
negative regulation of molecular function GO:0044092 23 0.016
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.016
segmentation GO:0035282 97 0.015
chemical homeostasis GO:0048878 49 0.015
Zebrafish Fly
catecholamine metabolic process GO:0006584 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
intracellular signal transduction GO:0035556 85 0.015
determination of left right symmetry GO:0007368 179 0.015
regulation of lipid catabolic process GO:0050994 2 0.015
response to lipid GO:0033993 60 0.015
aorta morphogenesis GO:0035909 3 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
response to uv GO:0009411 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Human Mouse
regulation of vascular permeability GO:0043114 5 0.015
regulation of dna replication GO:0006275 3 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of protein catabolic process GO:0042176 1 0.015
embryonic appendage morphogenesis GO:0035113 30 0.015
single organism cellular localization GO:1902580 46 0.015
liver development GO:0001889 96 0.015
regulation of protein complex assembly GO:0043254 3 0.014
response to drug GO:0042493 3 0.014
Human
stem cell differentiation GO:0048863 117 0.014
inositol phosphate biosynthetic process GO:0032958 1 0.014
inositol phosphate metabolic process GO:0043647 1 0.014
protein polymerization GO:0051258 4 0.014
cell cell signaling GO:0007267 52 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of cellular process GO:0048522 201 0.014
Human
neurological system process GO:0050877 62 0.014
organic hydroxy compound metabolic process GO:1901615 16 0.014
trabecula morphogenesis GO:0061383 2 0.014
response to transition metal nanoparticle GO:1990267 28 0.014
regulation of gtpase activity GO:0043087 2 0.014
single organism organelle organization GO:1902589 199 0.014
growth GO:0040007 174 0.014
adult behavior GO:0030534 2 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
peripheral nervous system development GO:0007422 55 0.014
intracellular mrna localization GO:0008298 1 0.014
response to other organism GO:0051707 97 0.014
heart development GO:0007507 313 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
macromolecule localization GO:0033036 54 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
multi organism process GO:0051704 134 0.013
positive regulation of glial cell differentiation GO:0045687 1 0.013
oxidation reduction process GO:0055114 41 0.013
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
gastrulation GO:0007369 208 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
aorta development GO:0035904 4 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
rna localization GO:0006403 4 0.013
nitric oxide metabolic process GO:0046209 2 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
axon development GO:0061564 166 0.013
negative regulation of signal transduction GO:0009968 94 0.013
regulation of embryonic development GO:0045995 47 0.013
somatic muscle development GO:0007525 4 0.013
cellular component biogenesis GO:0044085 178 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
fatty acid catabolic process GO:0009062 1 0.013
positive regulation of carbohydrate metabolic process GO:0045913 1 0.013
urogenital system development GO:0001655 97 0.013
positive regulation of cytokine production GO:0001819 2 0.013
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.013
fatty acid oxidation GO:0019395 1 0.013
protein complex disassembly GO:0043241 1 0.013
water homeostasis GO:0030104 4 0.013
cell substrate adhesion GO:0031589 4 0.013
positive regulation of neuron death GO:1901216 1 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
organophosphate metabolic process GO:0019637 37 0.012
zymogen activation GO:0031638 3 0.012
regulation of alcohol biosynthetic process GO:1902930 1 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
fin morphogenesis GO:0033334 53 0.012
regulation of gastrulation GO:0010470 24 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
lymph vessel development GO:0001945 27 0.012
appendage morphogenesis GO:0035107 56 0.012
phagocytosis engulfment GO:0006911 1 0.012
collagen biosynthetic process GO:0032964 2 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
regulation of cell development GO:0060284 100 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
lateral line system development GO:0048925 76 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
muscle cell differentiation GO:0042692 139 0.012
negative regulation of epithelial cell migration GO:0010633 1 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
protein secretion GO:0009306 1 0.012
regulation of reproductive process GO:2000241 4 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cellular response to nutrient levels GO:0031669 2 0.012
lymph vessel morphogenesis GO:0036303 25 0.012
developmental programmed cell death GO:0010623 4 0.012
neuronal action potential GO:0019228 18 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
spinal cord motor neuron differentiation GO:0021522 26 0.012
negative regulation of cell death GO:0060548 60 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
cell proliferation in hindbrain GO:0021534 4 0.011
ectodermal placode formation GO:0060788 26 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
ectodermal placode morphogenesis GO:0071697 32 0.011
hatching gland development GO:0048785 3 0.011
regulation of growth GO:0040008 42 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.011
lateral inhibition GO:0046331 1 0.011
leukocyte activation GO:0045321 12 0.011
positive regulation of secretion GO:0051047 1 0.011
multi organism cellular process GO:0044764 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
response to hormone GO:0009725 48 0.011
cilium morphogenesis GO:0060271 85 0.011

nr1i2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.129
connective tissue disease DOID:65 0 0.053
bone disease DOID:0080001 0 0.053
musculoskeletal system disease DOID:17 0 0.053
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017