|
|
hormone mediated signaling pathway
|
GO:0009755 |
9 |
0.758
|
Fly |
|
|
signal transduction
|
GO:0007165 |
455 |
0.514
|
Fly |
|
|
cognition
|
GO:0050890 |
1 |
0.505
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.326
|
Mouse Worm |
|
|
female gonad development
|
GO:0008585 |
4 |
0.310
|
Mouse Rat |
|
|
lipid storage
|
GO:0019915 |
1 |
0.284
|
Worm |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.199
|
Mouse Worm |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.195
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.192
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.182
|
Zebrafish Mouse |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.177
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.177
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
387 |
0.175
|
Zebrafish Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.173
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.162
|
Fly |
|
|
segmentation
|
GO:0035282 |
97 |
0.158
|
Fly |
|
|
larval development
|
GO:0002164 |
2 |
0.152
|
Worm |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.150
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.149
|
Fly |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.148
|
Zebrafish Mouse Rat Fly |
|
|
urogenital system development
|
GO:0001655 |
97 |
0.144
|
|
|
|
hormone metabolic process
|
GO:0042445 |
19 |
0.141
|
Mouse |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.139
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.139
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.134
|
Fly |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.133
|
Zebrafish Mouse Rat Fly |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.131
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.129
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.123
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.118
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.117
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.116
|
|
|
|
aging
|
GO:0007568 |
2 |
0.115
|
Mouse |
|
|
death
|
GO:0016265 |
121 |
0.115
|
Worm |
|
|
lipid catabolic process
|
GO:0016042 |
4 |
0.114
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.112
|
Fly |
|
|
homeostatic process
|
GO:0042592 |
142 |
0.112
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.107
|
Mouse |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.107
|
Zebrafish Mouse Rat Fly |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.105
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.105
|
Zebrafish Mouse Rat Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.104
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.102
|
Mouse Rat |
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.100
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.100
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.100
|
Fly |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.099
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
4 |
0.096
|
Mouse Rat |
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.096
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.095
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.094
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
30 |
0.094
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.091
|
Worm |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.091
|
Worm |
|
|
endocrine system development
|
GO:0035270 |
65 |
0.090
|
Zebrafish Mouse |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.089
|
Zebrafish Mouse Rat Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.089
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
1 |
0.088
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.087
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.087
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.085
|
Zebrafish Mouse Fly |
|
|
cell death
|
GO:0008219 |
121 |
0.081
|
Worm |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.080
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.078
|
Zebrafish Mouse Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.077
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.076
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.076
|
Fly |
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.076
|
Zebrafish Mouse Rat Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.074
|
|
|
|
tissue homeostasis
|
GO:0001894 |
25 |
0.074
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.074
|
|
|
|
response to hormone
|
GO:0009725 |
48 |
0.073
|
Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
22 |
0.073
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.072
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.072
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.069
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.069
|
Worm |
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.068
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.068
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.068
|
Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.068
|
Zebrafish Mouse Rat Fly |
|
|
cation homeostasis
|
GO:0055080 |
33 |
0.067
|
|
|
|
post embryonic morphogenesis
|
GO:0009886 |
4 |
0.067
|
Fly |
|
|
protein import
|
GO:0017038 |
3 |
0.067
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.066
|
Zebrafish Mouse Rat Fly |
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.064
|
Mouse |
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.063
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.062
|
Worm |
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.062
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
4 |
0.062
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.062
|
Zebrafish |
|
|
pancreas development
|
GO:0031016 |
84 |
0.062
|
Zebrafish |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.061
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.061
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
45 |
0.061
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.061
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.060
|
Zebrafish Mouse Rat Fly |
|
|
somitogenesis
|
GO:0001756 |
87 |
0.060
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.059
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.059
|
Zebrafish Mouse Rat Fly |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.059
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.059
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
79 |
0.057
|
|
|
|
head development
|
GO:0060322 |
303 |
0.057
|
Zebrafish Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.057
|
|
|
|
lipid homeostasis
|
GO:0055088 |
3 |
0.057
|
Fly |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.057
|
Zebrafish Mouse Fly |
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.056
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.056
|
Worm |
|
|
heart development
|
GO:0007507 |
313 |
0.056
|
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.056
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.055
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.055
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.055
|
Worm |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.055
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
2 |
0.055
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.055
|
|
|
|
system process
|
GO:0003008 |
185 |
0.054
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.053
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.053
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.053
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.053
|
Zebrafish Mouse Rat Fly |
|
|
brain development
|
GO:0007420 |
293 |
0.053
|
Zebrafish Fly |
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
1 |
0.052
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
74 |
0.052
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.052
|
Zebrafish |
|
|
ovulation cycle
|
GO:0042698 |
2 |
0.052
|
Mouse |
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
1 |
0.051
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
2 |
0.051
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.051
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.049
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.049
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.049
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.048
|
Zebrafish Mouse Rat Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.048
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.048
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.048
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.048
|
|
|
|
transport
|
GO:0006810 |
220 |
0.047
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.047
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.047
|
Fly |
|
|
renal system development
|
GO:0072001 |
94 |
0.047
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.046
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.046
|
Zebrafish Mouse Rat Fly |
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.046
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.046
|
Zebrafish Mouse Rat Fly |
|
|
photoreceptor cell fate commitment
|
GO:0046552 |
1 |
0.046
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.045
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.044
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.044
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.044
|
Zebrafish Mouse Rat Fly |
|
|
growth
|
GO:0040007 |
174 |
0.044
|
Worm |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.044
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.044
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
23 |
0.043
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.042
|
Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.042
|
Worm |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
3 |
0.042
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.042
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.042
|
Mouse Worm Fly |
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.042
|
Zebrafish Mouse Rat Fly |
|
|
embryonic camera type eye development
|
GO:0031076 |
29 |
0.041
|
|
|
|
myotube differentiation
|
GO:0014902 |
45 |
0.041
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.041
|
Worm |
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.041
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.041
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.041
|
|
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.040
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.040
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.040
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.040
|
Zebrafish Mouse Worm Fly |
|
|
regulation of receptor activity
|
GO:0010469 |
2 |
0.040
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
2 |
0.039
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
3 |
0.039
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.039
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
109 |
0.039
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.039
|
|
|
|
neural retina development
|
GO:0003407 |
49 |
0.039
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
4 |
0.039
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.039
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.038
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.038
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.038
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.038
|
Zebrafish Mouse Rat Fly |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.038
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.037
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.037
|
Fly |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.037
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.037
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.037
|
Mouse |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.037
|
Zebrafish Mouse Rat Fly |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.036
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.036
|
Worm |
|
|
circulatory system process
|
GO:0003013 |
87 |
0.035
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.035
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.035
|
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.035
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.035
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.035
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.035
|
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.035
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.035
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.034
|
|
|
|
regulation of response to nutrient levels
|
GO:0032107 |
1 |
0.034
|
|
|
|
ion homeostasis
|
GO:0050801 |
41 |
0.034
|
|
|
|
mechanosensory behavior
|
GO:0007638 |
2 |
0.034
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
32 |
0.034
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.034
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.033
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.033
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.033
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.033
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.032
|
Zebrafish Mouse Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.032
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.032
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.032
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.032
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.032
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.031
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.031
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
7 |
0.031
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.031
|
Zebrafish Mouse Rat Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.031
|
Fly |
|
|
long chain fatty acid metabolic process
|
GO:0001676 |
1 |
0.031
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.030
|
Zebrafish Mouse Rat Fly |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.030
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.030
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.030
|
|
|
|
negative regulation of feeding behavior
|
GO:2000252 |
2 |
0.030
|
|
|
|
diencephalon development
|
GO:0021536 |
58 |
0.030
|
Zebrafish |
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.029
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.029
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.028
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
3 |
0.028
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.028
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.028
|
Zebrafish Mouse Fly |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.028
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
1 |
0.028
|
|
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
1 |
0.027
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.027
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.027
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
26 |
0.027
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.027
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
19 |
0.027
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.027
|
Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
3 |
0.026
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.026
|
|
|
|
somatic muscle development
|
GO:0007525 |
4 |
0.026
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.026
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.026
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
2 |
0.026
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.026
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
3 |
0.026
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.025
|
|
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.025
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.025
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.025
|
Zebrafish Mouse Rat Fly |
|
|
peptide transport
|
GO:0015833 |
1 |
0.025
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
42 |
0.025
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
10 |
0.025
|
|
|
|
long chain fatty acid transport
|
GO:0015909 |
1 |
0.025
|
|
|
|
hormone transport
|
GO:0009914 |
2 |
0.025
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.025
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
6 |
0.025
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.025
|
Zebrafish |
|
|
sex determination
|
GO:0007530 |
1 |
0.024
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
10 |
0.024
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.024
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.024
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.024
|
Fly |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.024
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.024
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
2 |
0.023
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
3 |
0.023
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.023
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.023
|
|
|
|
camera type eye photoreceptor cell differentiation
|
GO:0060219 |
19 |
0.023
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
2 |
0.023
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.023
|
|
|
|
tissue remodeling
|
GO:0048771 |
4 |
0.023
|
|
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.023
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.023
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.023
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
65 |
0.023
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.023
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.023
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.023
|
Zebrafish Mouse Rat Fly |
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.022
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.022
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
1 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
13 |
0.022
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.022
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of cell division
|
GO:0051781 |
2 |
0.022
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.022
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
10 |
0.022
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.022
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.022
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.022
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.022
|
Worm |
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.022
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.022
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
2 |
0.022
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.022
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
2 |
0.022
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.022
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
2 |
0.022
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
3 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.021
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.021
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
4 |
0.021
|
|
|
|
water homeostasis
|
GO:0030104 |
4 |
0.021
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.021
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
2 |
0.021
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
2 |
0.021
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.021
|
|
|
|
protein secretion
|
GO:0009306 |
1 |
0.021
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
2 |
0.021
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
3 |
0.021
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.021
|
|
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.021
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.021
|
|
|
|
fatty acid transport
|
GO:0015908 |
1 |
0.021
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
13 |
0.020
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.020
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.020
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
3 |
0.020
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.020
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
25 |
0.020
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.020
|
|
|
|
cation transport
|
GO:0006812 |
81 |
0.020
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.020
|
Zebrafish Mouse Fly |
|
|
cellular hormone metabolic process
|
GO:0034754 |
19 |
0.020
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
19 |
0.019
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.019
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
1 |
0.019
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.019
|
Zebrafish Mouse Fly |
|
|
adult behavior
|
GO:0030534 |
2 |
0.019
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.019
|
Zebrafish Mouse Rat Fly |
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.019
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.019
|
|
|
|
chemical homeostasis
|
GO:0048878 |
49 |
0.019
|
Fly |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.019
|
Mouse |
|
|
cell matrix adhesion
|
GO:0007160 |
4 |
0.019
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.019
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.018
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.018
|
Mouse |
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
1 |
0.018
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.018
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.018
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.018
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
2 |
0.018
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
10 |
0.018
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.018
|
|
|
|
single organism behavior
|
GO:0044708 |
24 |
0.018
|
Fly |
|
|
protein homooligomerization
|
GO:0051260 |
3 |
0.018
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.018
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.018
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
2 |
0.017
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.017
|
|
|
|
transmembrane transport
|
GO:0055085 |
120 |
0.017
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.017
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
3 |
0.017
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
2 |
0.017
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.017
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.017
|
|
|
|
photoreceptor cell fate specification
|
GO:0043704 |
1 |
0.017
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.017
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.017
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.017
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.017
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.017
|
Worm |
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
1 |
0.017
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.017
|
|
|
|
neural tube patterning
|
GO:0021532 |
33 |
0.017
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.016
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.016
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.016
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.016
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.016
|
Zebrafish Mouse Rat Fly |
|
|
hindbrain development
|
GO:0030902 |
91 |
0.016
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.016
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.016
|
Worm |
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.016
|
Mouse Rat Worm |
|
|
cellular ion homeostasis
|
GO:0006873 |
17 |
0.016
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.016
|
Zebrafish Mouse Rat Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.016
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.016
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
91 |
0.016
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.016
|
|
|
|
autophagy
|
GO:0006914 |
4 |
0.016
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.016
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
1 |
0.016
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.016
|
|
|
|
androgen metabolic process
|
GO:0008209 |
2 |
0.015
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
38 |
0.015
|
Worm |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.015
|
Zebrafish Mouse Fly |
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.015
|
|
|
|
pectoral fin development
|
GO:0033339 |
50 |
0.015
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.015
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.015
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.015
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
4 |
0.015
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.015
|
Zebrafish Mouse Fly |
|
|
post embryonic organ development
|
GO:0048569 |
4 |
0.015
|
Worm Fly |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
3 |
0.015
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.015
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.015
|
Mouse Worm |
|
|
ion transport
|
GO:0006811 |
114 |
0.015
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.015
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.015
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.015
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.015
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
3 |
0.015
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
30 |
0.014
|
|
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.014
|
|
|
|
membrane repolarization
|
GO:0086009 |
2 |
0.014
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
10 |
0.014
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.014
|
Worm |
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.014
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.014
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
23 |
0.014
|
|
|
|
regulation of protein processing
|
GO:0070613 |
10 |
0.014
|
|
|
|
retina layer formation
|
GO:0010842 |
24 |
0.014
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
21 |
0.014
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.014
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
35 |
0.014
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.014
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
2 |
0.014
|
Mouse |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.014
|
Zebrafish Mouse Rat Fly |
|
|
lymphangiogenesis
|
GO:0001946 |
25 |
0.014
|
|
|
|
otic vesicle development
|
GO:0071599 |
42 |
0.014
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.014
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
17 |
0.014
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.014
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.014
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.014
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.014
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
2 |
0.014
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.014
|
|
|
|
protein polymerization
|
GO:0051258 |
4 |
0.013
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.013
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.013
|
Zebrafish Mouse Rat Fly |
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.013
|
Mouse Rat Worm |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.013
|
Zebrafish Mouse Fly |
|
|
vasculature development
|
GO:0001944 |
278 |
0.013
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.013
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.013
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.013
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.013
|
Mouse |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.013
|
Zebrafish Mouse Rat Fly |
|
|
axon guidance
|
GO:0007411 |
86 |
0.013
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.013
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
9 |
0.013
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.013
|
Zebrafish Mouse Rat Fly |
|
|
inner ear morphogenesis
|
GO:0042472 |
63 |
0.013
|
|
|
|
specification of axis polarity
|
GO:0065001 |
4 |
0.013
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
4 |
0.013
|
|
|
|
bone remodeling
|
GO:0046849 |
2 |
0.013
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.013
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.013
|
|
|
|
protein localization
|
GO:0008104 |
40 |
0.013
|
Mouse |
|
|
skin development
|
GO:0043588 |
54 |
0.013
|
|
|
|
steroid metabolic process
|
GO:0008202 |
7 |
0.013
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.013
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
1 |
0.013
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.013
|
|
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.013
|
Mouse Worm |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.013
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.013
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
2 |
0.013
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
4 |
0.012
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.012
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.012
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.012
|
Fly |
|
|
immune system process
|
GO:0002376 |
241 |
0.012
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.012
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
10 |
0.012
|
|
|
|
regulation of bone remodeling
|
GO:0046850 |
2 |
0.012
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.012
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.012
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.012
|
Zebrafish Mouse Fly |
|
|
opioid receptor signaling pathway
|
GO:0038003 |
3 |
0.012
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.012
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.012
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
21 |
0.012
|
Mouse |
|
|
intracellular transport
|
GO:0046907 |
32 |
0.012
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.012
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.012
|
|
|
|
epiboly
|
GO:0090504 |
41 |
0.012
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
4 |
0.012
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
4 |
0.012
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.012
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
16 |
0.012
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
29 |
0.011
|
|
