Danio rerio

18 known processes

nrxn1a

neurexin 1a

nrxn1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
specification of symmetry GO:0009799 204 0.502
striated muscle tissue development GO:0014706 110 0.429
generation of neurons GO:0048699 385 0.313
Zebrafish
skeletal muscle organ development GO:0060538 78 0.286
positive regulation of cellular process GO:0048522 201 0.264
negative regulation of biological process GO:0048519 304 0.227
muscle structure development GO:0061061 196 0.217
embryonic heart tube development GO:0035050 133 0.182
single organism localization GO:1902578 225 0.171
regulation of multicellular organism growth GO:0040014 4 0.160
cellular nitrogen compound metabolic process GO:0034641 290 0.159
regulation of mrna processing GO:0050684 3 0.158
larval development GO:0002164 2 0.149
cellular aromatic compound metabolic process GO:0006725 295 0.147
maintenance of location GO:0051235 4 0.147
regulation of developmental process GO:0050793 247 0.125
vasculature development GO:0001944 278 0.123
segmentation GO:0035282 97 0.112
regulation of mrna splicing via spliceosome GO:0048024 3 0.108
regulation of macromolecule metabolic process GO:0060255 317 0.107
response to organic substance GO:0010033 153 0.105
organic cyclic compound metabolic process GO:1901360 301 0.103
locomotion GO:0040011 313 0.103
Zebrafish
positive regulation of biological process GO:0048518 253 0.097
striated muscle cell development GO:0055002 108 0.097
response to carbohydrate GO:0009743 3 0.095
regulation of multicellular organismal process GO:0051239 277 0.094
organelle fusion GO:0048284 3 0.093
negative regulation of axon extension GO:0030517 7 0.093
regulation of synapse assembly GO:0051963 3 0.091
cellular component assembly GO:0022607 170 0.088
macromolecule biosynthetic process GO:0009059 227 0.082
establishment of localization GO:0051234 244 0.081
skeletal muscle tissue development GO:0007519 67 0.080
synaptic transmission GO:0007268 35 0.078
Zebrafish
localization of cell GO:0051674 244 0.077
neuron development GO:0048666 262 0.077
Zebrafish
cell migration GO:0016477 237 0.075
macromolecular complex subunit organization GO:0043933 74 0.074
regulation of gene expression GO:0010468 265 0.074
lipid storage GO:0019915 1 0.073
determination of left right symmetry GO:0007368 179 0.072
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.071
axonogenesis GO:0007409 152 0.070
Zebrafish
regulation of synapse organization GO:0050807 3 0.070
multicellular organism growth GO:0035264 4 0.069
heart development GO:0007507 313 0.069
cell morphogenesis GO:0000902 289 0.068
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.066
muscle organ development GO:0007517 101 0.066
neuromuscular synaptic transmission GO:0007274 2 0.066
response to chemical GO:0042221 320 0.065
Zebrafish
heterocycle metabolic process GO:0046483 290 0.062
aging GO:0007568 2 0.062
ion transport GO:0006811 114 0.061
single organism transport GO:0044765 206 0.060
myotube differentiation GO:0014902 45 0.060
negative regulation of multicellular organismal process GO:0051241 69 0.059
gene expression GO:0010467 252 0.059
regulation of metabolic process GO:0019222 359 0.056
chemotaxis GO:0006935 104 0.054
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.053
mesoderm development GO:0007498 88 0.053
morphogenesis of an epithelium GO:0002009 333 0.052
regulation of membrane potential GO:0042391 23 0.051
negative regulation of cellular process GO:0048523 283 0.049
cognition GO:0050890 1 0.049
Human
response to wounding GO:0009611 116 0.049
ribosomal small subunit biogenesis GO:0042274 2 0.049
protein metabolic process GO:0019538 183 0.048
cellular component movement GO:0006928 335 0.048
Zebrafish
regionalization GO:0003002 274 0.048
cell motility GO:0048870 244 0.047
regulation of multicellular organismal development GO:2000026 223 0.047
response to glucose GO:0009749 3 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.045
taxis GO:0042330 109 0.045
Zebrafish
regulation of axon extension GO:0030516 24 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.045
muscle cell development GO:0055001 115 0.045
small molecule metabolic process GO:0044281 77 0.044
regulation of signaling GO:0023051 235 0.044
system process GO:0003008 185 0.043
Human
multi organism process GO:0051704 134 0.042
Human
positive regulation of catabolic process GO:0009896 4 0.042
single organism metabolic process GO:0044710 217 0.042
nucleic acid metabolic process GO:0090304 244 0.042
sensory organ morphogenesis GO:0090596 200 0.042
neuron differentiation GO:0030182 353 0.042
Zebrafish
embryonic organ development GO:0048568 381 0.041
regulation of signal transduction GO:0009966 225 0.041
eye morphogenesis GO:0048592 144 0.040
cell part morphogenesis GO:0032990 246 0.040
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.040
spliceosomal complex assembly GO:0000245 1 0.040
somitogenesis GO:0001756 87 0.039
regulation of cell communication GO:0010646 232 0.039
regulation of protein binding GO:0043393 3 0.038
membrane fusion GO:0061025 2 0.038
neurotransmitter secretion GO:0007269 2 0.037
regulation of cellular component organization GO:0051128 86 0.037
heart looping GO:0001947 94 0.037
specification of axis polarity GO:0065001 4 0.037
cellular protein metabolic process GO:0044267 129 0.036
regulation of localization GO:0032879 104 0.036
regulation of axonogenesis GO:0050770 32 0.036
cellular component morphogenesis GO:0032989 336 0.036
Zebrafish
regulation of biological quality GO:0065008 263 0.036
single organism membrane fusion GO:0044801 2 0.036
transcription dna templated GO:0006351 181 0.036
response to hexose GO:0009746 3 0.035
synaptic vesicle localization GO:0097479 1 0.035
cation transport GO:0006812 81 0.035
muscle fiber development GO:0048747 52 0.035
regulation of neurotransmitter secretion GO:0046928 1 0.034
multicellular organismal signaling GO:0035637 22 0.034
positive regulation of transport GO:0051050 2 0.034
cellular response to organic substance GO:0071310 105 0.034
skeletal muscle fiber development GO:0048741 35 0.034
neural crest cell development GO:0014032 62 0.034
ion transmembrane transport GO:0034220 91 0.033
striated muscle cell differentiation GO:0051146 129 0.033
neurotransmitter transport GO:0006836 2 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
exocytosis GO:0006887 1 0.033
anterior posterior pattern specification GO:0009952 152 0.033
regulation of synaptic vesicle transport GO:1902803 1 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
embryonic organ morphogenesis GO:0048562 274 0.032
regulation of neurotransmitter transport GO:0051588 1 0.032
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.032
oocyte maturation GO:0001556 4 0.031
neuron neuron synaptic transmission GO:0007270 1 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.031
i kappab kinase nf kappab signaling GO:0007249 4 0.030
regulation of cellular component size GO:0032535 30 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
catabolic process GO:0009056 32 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
developmental growth GO:0048589 166 0.029
negative regulation of mrna metabolic process GO:1903312 3 0.029
regulation of growth GO:0040008 42 0.029
eye development GO:0001654 277 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
cellular protein modification process GO:0006464 100 0.028
cellular response to external stimulus GO:0071496 2 0.028
adult behavior GO:0030534 2 0.027
Human
negative regulation of cellular component organization GO:0051129 16 0.027
regulation of cell projection organization GO:0031344 44 0.027
regulation of cell morphogenesis GO:0022604 42 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
protein modification process GO:0036211 100 0.026
response to stress GO:0006950 263 0.026
regulation of cell growth GO:0001558 29 0.026
regulation of developmental growth GO:0048638 38 0.026
cellular component biogenesis GO:0044085 178 0.026
cellular catabolic process GO:0044248 27 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
cation transmembrane transport GO:0098655 65 0.026
gtp metabolic process GO:0046039 4 0.026
axon guidance GO:0007411 86 0.026
Zebrafish
transmembrane transport GO:0055085 120 0.025
retina morphogenesis in camera type eye GO:0060042 79 0.025
regulation of locomotion GO:0040012 55 0.025
cellular biosynthetic process GO:0044249 286 0.025
establishment of localization in cell GO:0051649 77 0.025
protein homooligomerization GO:0051260 3 0.024
regulation of neuron projection development GO:0010975 40 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
behavior GO:0007610 74 0.024
Human
macromolecular complex assembly GO:0065003 35 0.024
rna metabolic process GO:0016070 219 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
mrna metabolic process GO:0016071 20 0.023
response to monosaccharide GO:0034284 3 0.023
regulation of biosynthetic process GO:0009889 250 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
mesenchyme development GO:0060485 127 0.023
regulation of cellular component movement GO:0051270 55 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
establishment of monopolar cell polarity GO:0061162 2 0.022
response to alkaloid GO:0043279 2 0.022
positive regulation of cell division GO:0051781 2 0.022
regulation of dna templated transcription in response to stress GO:0043620 0 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
single organism organelle organization GO:1902589 199 0.022
oxoacid metabolic process GO:0043436 31 0.022
neurological system process GO:0050877 62 0.022
Human
synaptic vesicle recycling GO:0036465 1 0.022
rna processing GO:0006396 25 0.022
convergent extension GO:0060026 118 0.022
cellular amine metabolic process GO:0044106 2 0.022
atp catabolic process GO:0006200 4 0.021
growth GO:0040007 174 0.021
regulation of wound healing GO:0061041 2 0.021
sex determination GO:0007530 1 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
heart morphogenesis GO:0003007 156 0.021
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.021
cellular response to lipopolysaccharide GO:0071222 3 0.021
cell adhesion GO:0007155 40 0.021
positive regulation of epithelial cell proliferation GO:0050679 1 0.021
regulation of extent of cell growth GO:0061387 29 0.021
regulation of rna metabolic process GO:0051252 224 0.021
regulation of nervous system development GO:0051960 90 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
transmission of nerve impulse GO:0019226 19 0.020
positive regulation of cell cycle GO:0045787 3 0.020
positive regulation of mrna metabolic process GO:1903313 2 0.020
regulation of neurogenesis GO:0050767 87 0.020
negative regulation of rna metabolic process GO:0051253 48 0.020
chordate embryonic development GO:0043009 271 0.020
response to external stimulus GO:0009605 264 0.020
Human Zebrafish
transport GO:0006810 220 0.020
signal transduction GO:0007165 455 0.020
regulation of organelle assembly GO:1902115 4 0.020
neural crest cell migration GO:0001755 42 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
cell death GO:0008219 121 0.019
sensory organ development GO:0007423 393 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
anatomical structure homeostasis GO:0060249 36 0.019
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.019
rna splicing GO:0008380 16 0.019
nucleic acid templated transcription GO:0097659 181 0.019
carbohydrate homeostasis GO:0033500 1 0.019
somite development GO:0061053 96 0.019
cytosolic calcium ion transport GO:0060401 3 0.019
central nervous system development GO:0007417 387 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.018
positive regulation of lipid metabolic process GO:0045834 1 0.018
macromolecular complex disassembly GO:0032984 1 0.018
female sex differentiation GO:0046660 4 0.018
macromolecule modification GO:0043412 111 0.018
nitrogen compound transport GO:0071705 23 0.018
regulation of anatomical structure size GO:0090066 33 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
epithelial cell migration GO:0010631 25 0.017
negative regulation of chemotaxis GO:0050922 4 0.017
regulation of cell development GO:0060284 100 0.017
regulation of response to stress GO:0080134 36 0.017
muscle tissue development GO:0060537 110 0.017
establishment of apical basal cell polarity GO:0035089 2 0.017
negative regulation of muscle cell differentiation GO:0051148 1 0.017
negative regulation of mrna processing GO:0050686 1 0.017
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.017
blood vessel development GO:0001568 246 0.017
neuron projection morphogenesis GO:0048812 161 0.017
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.017
rna localization GO:0006403 4 0.017
cellular response to starvation GO:0009267 1 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
amine metabolic process GO:0009308 2 0.016
negative regulation of developmental process GO:0051093 65 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
pronephros morphogenesis GO:0072114 14 0.016
peptide transport GO:0015833 1 0.016
synaptic vesicle transport GO:0048489 1 0.016
negative regulation of gliogenesis GO:0014014 1 0.016
cellular localization GO:0051641 97 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of metal ion transport GO:0010959 4 0.016
positive regulation of wound healing GO:0090303 1 0.016
organic substance catabolic process GO:1901575 28 0.016
response to nitrogen compound GO:1901698 19 0.016
organelle localization GO:0051640 49 0.015
regulation of cell shape GO:0008360 1 0.015
sequestering of metal ion GO:0051238 3 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
single organism behavior GO:0044708 24 0.015
Human
developmental pigmentation GO:0048066 48 0.015
negative regulation of gene expression GO:0010629 65 0.015
female gonad development GO:0008585 4 0.015
regulation of protein complex assembly GO:0043254 3 0.015
hormone secretion GO:0046879 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
heart jogging GO:0003146 40 0.015
blood vessel morphogenesis GO:0048514 216 0.015
apoptotic process GO:0006915 116 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
ovulation cycle GO:0042698 2 0.015
immune system development GO:0002520 191 0.015
positive regulation of dna templated transcription elongation GO:0032786 1 0.015
cellular response to stress GO:0033554 62 0.015
regulation of cell migration GO:0030334 40 0.015
diencephalon development GO:0021536 58 0.015
phosphorus metabolic process GO:0006793 109 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
Zebrafish
regulation of cell differentiation GO:0045595 142 0.014
wound healing GO:0042060 90 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
myotube cell development GO:0014904 35 0.014
glucose homeostasis GO:0042593 1 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
epithelium migration GO:0090132 25 0.014
negative regulation of cell death GO:0060548 60 0.014
ph reduction GO:0045851 1 0.014
organic substance biosynthetic process GO:1901576 289 0.014
skeletal system development GO:0001501 181 0.014
cell cell signaling GO:0007267 52 0.014
Zebrafish
positive regulation of cell substrate adhesion GO:0010811 1 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
renal system development GO:0072001 94 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
regulation of neurological system process GO:0031644 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
action potential GO:0001508 19 0.014
gland development GO:0048732 143 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
positive regulation of mrna splicing via spliceosome GO:0048026 1 0.013
protein secretion GO:0009306 1 0.013
tissue migration GO:0090130 37 0.013
regulation of tube size GO:0035150 2 0.013
regulation of cell size GO:0008361 29 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
nephron tubule morphogenesis GO:0072078 1 0.013
angiogenesis GO:0001525 158 0.013
reflex GO:0060004 2 0.013
sprouting angiogenesis GO:0002040 53 0.013
intracellular signal transduction GO:0035556 85 0.013
response to lipid GO:0033993 60 0.013
protein localization GO:0008104 40 0.013
negative regulation of rna splicing GO:0033119 1 0.013
response to vitamin GO:0033273 3 0.013
negative regulation of metabolic process GO:0009892 86 0.013
cell migration involved in heart development GO:0060973 22 0.013
regulation of homeostatic process GO:0032844 9 0.013
homeostatic process GO:0042592 142 0.013
negative regulation of growth GO:0045926 10 0.012
cytokinesis GO:0000910 3 0.012
lipid metabolic process GO:0006629 52 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
energy reserve metabolic process GO:0006112 2 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
protein complex biogenesis GO:0070271 30 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
regulation of receptor activity GO:0010469 2 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
negative regulation of neuron projection regeneration GO:0070571 4 0.012
gtp catabolic process GO:0006184 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
response to oxygen containing compound GO:1901700 55 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
cell projection morphogenesis GO:0048858 244 0.012
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.012
regulation of intracellular ph GO:0051453 1 0.012
regulation of transport GO:0051049 45 0.012
response to inorganic substance GO:0010035 38 0.012
regulation of protein targeting GO:1903533 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
positive regulation of developmental process GO:0051094 50 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
positive regulation of metabolic process GO:0009893 108 0.012
organic acid metabolic process GO:0006082 31 0.012
cellular component disassembly GO:0022411 1 0.012
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of exocytosis GO:0017157 1 0.011
axon development GO:0061564 166 0.011
Zebrafish
retina development in camera type eye GO:0060041 146 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of blood pressure GO:0008217 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
vesicle localization GO:0051648 27 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
regulation of cell motility GO:2000145 46 0.011
regulation of jak stat cascade GO:0046425 3 0.011
mechanosensory behavior GO:0007638 2 0.011
Human
death GO:0016265 121 0.011
biological adhesion GO:0022610 40 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of hormone secretion GO:0046883 2 0.011
cellular lipid metabolic process GO:0044255 36 0.011
positive regulation of cell differentiation GO:0045597 30 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
membrane repolarization GO:0086009 2 0.011
autophagy GO:0006914 4 0.011
regulation of dendrite development GO:0050773 3 0.011
organelle organization GO:0006996 227 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of reproductive process GO:2000241 4 0.011
vesicle organization GO:0016050 6 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
hormone transport GO:0009914 2 0.011
negative regulation of cell projection organization GO:0031345 9 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
convergent extension involved in organogenesis GO:0060029 10 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
synaptic transmission cholinergic GO:0007271 4 0.010
cardiac muscle fiber development GO:0048739 3 0.010
hard palate development GO:0060022 4 0.010
synapse organization GO:0050808 21 0.010
protein complex subunit organization GO:0071822 46 0.010
response to unfolded protein GO:0006986 2 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010
macroautophagy GO:0016236 1 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
muscle cell differentiation GO:0042692 139 0.010

nrxn1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.026
aplastic anemia DOID:12449 0 0.026
disease of anatomical entity DOID:7 0 0.026
bone marrow disease DOID:4961 0 0.026
anemia DOID:2355 0 0.026
hematopoietic system disease DOID:74 0 0.026