Danio rerio

111 known processes

nsfa

N-ethylmaleimide-sensitive factor a

(Aliases: wu:fj33g11,si:bz18k17.1,nsf)

nsfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.985
sensory organ development GO:0007423 393 0.854
neuron differentiation GO:0030182 353 0.785
cellular component assembly GO:0022607 170 0.685
Worm Fly
organelle localization GO:0051640 49 0.640
single organism localization GO:1902578 225 0.563
Worm Fly
neuron projection development GO:0031175 180 0.440
neuron development GO:0048666 262 0.406
establishment of vesicle localization GO:0051650 24 0.373
Fly
synaptic transmission GO:0007268 35 0.373
Fly
response to external stimulus GO:0009605 264 0.350
multicellular organismal signaling GO:0035637 22 0.346
cell cell signaling GO:0007267 52 0.344
Fly
larval development GO:0002164 2 0.338
Worm
neuromuscular process GO:0050905 7 0.311
regulation of multicellular organismal process GO:0051239 277 0.308
Fly
vesicle localization GO:0051648 27 0.289
organelle fusion GO:0048284 3 0.281
Fly
neurological system process GO:0050877 62 0.279
cellular component biogenesis GO:0044085 178 0.275
Worm Fly
establishment of localization GO:0051234 244 0.263
Worm Fly
single organism membrane fusion GO:0044801 2 0.245
Fly
head development GO:0060322 303 0.239
action potential GO:0001508 19 0.232
organelle organization GO:0006996 227 0.201
Worm Fly
ion transport GO:0006811 114 0.193
exocytosis GO:0006887 1 0.193
Fly
regulation of biological quality GO:0065008 263 0.193
transmission of nerve impulse GO:0019226 19 0.191
inorganic ion transmembrane transport GO:0098660 57 0.191
protein complex biogenesis GO:0070271 30 0.189
Worm Fly
macromolecular complex assembly GO:0065003 35 0.189
Worm Fly
larval behavior GO:0030537 5 0.180
brain development GO:0007420 293 0.171
membrane fusion GO:0061025 2 0.170
Fly
transport GO:0006810 220 0.164
Worm Fly
lateral line system development GO:0048925 76 0.150
system process GO:0003008 185 0.150
developmental growth GO:0048589 166 0.149
Fly
cellular protein complex assembly GO:0043623 19 0.149
Worm
neuron neuron synaptic transmission GO:0007270 1 0.143
cellular component movement GO:0006928 335 0.143
reflex GO:0060004 2 0.138
inorganic cation transmembrane transport GO:0098662 50 0.137
regulation of muscle contraction GO:0006937 3 0.137
growth GO:0040007 174 0.129
Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.125
Fly
fertilization GO:0009566 3 0.125
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.119
establishment of synaptic vesicle localization GO:0097480 1 0.118
Fly
establishment of organelle localization GO:0051656 45 0.116
Fly
embryonic organ development GO:0048568 381 0.099
neuromuscular process controlling balance GO:0050885 3 0.096
regulation of membrane potential GO:0042391 23 0.096
chordate embryonic development GO:0043009 271 0.093
morphogenesis of an epithelium GO:0002009 333 0.093
Fly
cell part morphogenesis GO:0032990 246 0.093
regulation of cell development GO:0060284 100 0.092
sensory system development GO:0048880 76 0.092
camera type eye development GO:0043010 222 0.092
nucleoside monophosphate catabolic process GO:0009125 4 0.090
Fly
single organism transport GO:0044765 206 0.087
Worm Fly
specification of symmetry GO:0009799 204 0.084
vesicle organization GO:0016050 6 0.083
Fly
regulation of localization GO:0032879 104 0.083
Fly
embryonic organ morphogenesis GO:0048562 274 0.081
regulation of neuron projection development GO:0010975 40 0.080
single organism organelle organization GO:1902589 199 0.080
Worm Fly
protein complex assembly GO:0006461 30 0.078
Worm Fly
protein complex subunit organization GO:0071822 46 0.074
Worm Fly
embryonic heart tube development GO:0035050 133 0.074
cation transmembrane transport GO:0098655 65 0.073
determination of bilateral symmetry GO:0009855 204 0.073
regulation of synaptic plasticity GO:0048167 1 0.070
Fly
regulation of synapse organization GO:0050807 3 0.069
Fly
cell projection morphogenesis GO:0048858 244 0.069
multicellular organism growth GO:0035264 4 0.068
ear development GO:0043583 127 0.067
synaptic vesicle localization GO:0097479 1 0.066
Fly
regulation of developmental process GO:0050793 247 0.063
Fly
regulation of synapse assembly GO:0051963 3 0.063
Fly
mitotic cell cycle GO:0000278 64 0.063
epithelial cell differentiation GO:0030855 116 0.061
cellular component morphogenesis GO:0032989 336 0.061
regionalization GO:0003002 274 0.060
establishment of localization in cell GO:0051649 77 0.060
Worm Fly
cellular macromolecular complex assembly GO:0034622 24 0.059
Worm
locomotory behavior GO:0007626 34 0.058
startle response GO:0001964 4 0.057
sensory organ morphogenesis GO:0090596 200 0.056
inner ear development GO:0048839 126 0.056
atp catabolic process GO:0006200 4 0.056
Fly
behavior GO:0007610 74 0.056
signal transduction GO:0007165 455 0.055
neurotransmitter secretion GO:0007269 2 0.054
Fly
regulation of cell shape GO:0008360 1 0.054
beta amyloid formation GO:0034205 1 0.053
neurotransmitter transport GO:0006836 2 0.053
Fly
cell projection organization GO:0030030 284 0.052
localization of cell GO:0051674 244 0.051
small molecule metabolic process GO:0044281 77 0.050
Fly
membrane repolarization GO:0086009 2 0.048
eye development GO:0001654 277 0.048
synaptic vesicle transport GO:0048489 1 0.048
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.047
heart morphogenesis GO:0003007 156 0.046
regulation of multicellular organism growth GO:0040014 4 0.046
synaptic transmission cholinergic GO:0007271 4 0.046
response to abiotic stimulus GO:0009628 122 0.045
vasculature development GO:0001944 278 0.043
blood vessel development GO:0001568 246 0.041
regulation of neuron differentiation GO:0045664 56 0.041
mechanoreceptor differentiation GO:0042490 37 0.040
heart jogging GO:0003146 40 0.040
protein metabolic process GO:0019538 183 0.038
lamellipodium assembly GO:0030032 1 0.037
synaptic vesicle recycling GO:0036465 1 0.037
purine nucleoside monophosphate catabolic process GO:0009128 4 0.036
Fly
mechanosensory lateral line system development GO:0048881 49 0.036
cytoskeleton organization GO:0007010 96 0.035
Worm
regulation of cell communication GO:0010646 232 0.035
Fly
single organism metabolic process GO:0044710 217 0.035
Fly
pigment granule localization GO:0051875 25 0.035
cation transport GO:0006812 81 0.035
homeostatic process GO:0042592 142 0.033
regulation of neuronal synaptic plasticity GO:0048168 1 0.033
Fly
macromolecular complex subunit organization GO:0043933 74 0.033
Worm Fly
determination of left right symmetry GO:0007368 179 0.031
visual perception GO:0007601 17 0.031
sensory perception GO:0007600 39 0.031
inner ear receptor cell development GO:0060119 20 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.030
Fly
chemosensory behavior GO:0007635 1 0.029
transmembrane transport GO:0055085 120 0.029
cellular component assembly involved in morphogenesis GO:0010927 107 0.029
Worm
microtubule based process GO:0007017 60 0.029
regulation of reproductive process GO:2000241 4 0.028
regulation of multicellular organismal development GO:2000026 223 0.027
Fly
kidney development GO:0001822 92 0.027
cellular localization GO:0051641 97 0.026
dopaminergic neuron differentiation GO:0071542 14 0.026
detection of abiotic stimulus GO:0009582 24 0.026
microtubule based transport GO:0010970 10 0.025
cell morphogenesis GO:0000902 289 0.025
single fertilization GO:0007338 3 0.025
response to mechanical stimulus GO:0009612 24 0.025
specification of axis polarity GO:0065001 4 0.024
muscle structure development GO:0061061 196 0.024
Worm
urogenital system development GO:0001655 97 0.024
regulation of cellular component organization GO:0051128 86 0.024
Fly
cytoskeleton dependent cytokinesis GO:0061640 3 0.024
skin development GO:0043588 54 0.024
adult behavior GO:0030534 2 0.023
tissue homeostasis GO:0001894 25 0.022
mechanosensory behavior GO:0007638 2 0.021
posterior lateral line system development GO:0048915 46 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
regulation of neurotransmitter levels GO:0001505 5 0.021
Fly
regulation of nervous system development GO:0051960 90 0.021
Fly
regulation of cell death GO:0010941 103 0.020
heart development GO:0007507 313 0.019
rna localization GO:0006403 4 0.019
pigmentation GO:0043473 85 0.018
metal ion transport GO:0030001 58 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
neuromast development GO:0048884 46 0.017
cellular nitrogen compound catabolic process GO:0044270 15 0.017
Fly
multi organism process GO:0051704 134 0.017
neuronal action potential GO:0019228 18 0.017
gtp metabolic process GO:0046039 4 0.016
epidermis development GO:0008544 48 0.016
notochord cell vacuolation GO:0060036 7 0.016
inner ear receptor cell fate commitment GO:0060120 4 0.016
cell motility GO:0048870 244 0.015
single organism reproductive process GO:0044702 40 0.015
sensory perception of sound GO:0007605 9 0.015
establishment of monopolar cell polarity GO:0061162 2 0.015
cell projection assembly GO:0030031 64 0.015
cognition GO:0050890 1 0.015
positive regulation of signaling GO:0023056 56 0.015
death GO:0016265 121 0.015
Worm
regulation of cell differentiation GO:0045595 142 0.014
hair cell differentiation GO:0035315 32 0.014
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.014
regulation of circadian rhythm GO:0042752 4 0.014
single organism behavior GO:0044708 24 0.014
eye morphogenesis GO:0048592 144 0.014
cranial nerve development GO:0021545 42 0.014
organic substance biosynthetic process GO:1901576 289 0.014
response to stress GO:0006950 263 0.014
organelle assembly GO:0070925 110 0.013
Worm
regulation of cell morphogenesis GO:0022604 42 0.013
macromolecular complex disassembly GO:0032984 1 0.013
Fly
larval locomotory behavior GO:0008345 5 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.013
establishment of spindle localization GO:0051293 12 0.013
cell death GO:0008219 121 0.013
Worm
single organism membrane organization GO:0044802 20 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
Fly
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.012
lipid storage GO:0019915 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
cell migration GO:0016477 237 0.012
ion transmembrane transport GO:0034220 91 0.012
polarized epithelial cell differentiation GO:0030859 4 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
response to light stimulus GO:0009416 46 0.012
epithelial cell development GO:0002064 42 0.012
positive regulation of cellular process GO:0048522 201 0.012
Fly
response to radiation GO:0009314 51 0.012
locomotion GO:0040011 313 0.012
negative regulation of cellular process GO:0048523 283 0.012
positive regulation of developmental process GO:0051094 50 0.012
detection of external stimulus GO:0009581 24 0.012
regulation of neuron migration GO:2001222 2 0.011
mitotic cell cycle process GO:1903047 48 0.011
response to chemical GO:0042221 320 0.011
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
regulation of response to stimulus GO:0048583 269 0.011
retina development in camera type eye GO:0060041 146 0.011
endocardial cell differentiation GO:0060956 5 0.011
regulation of cellular component biogenesis GO:0044087 12 0.011
Fly
aging GO:0007568 2 0.010
regulation of tube size GO:0035150 2 0.010
establishment of epithelial cell apical basal polarity GO:0045198 2 0.010
calcium mediated signaling GO:0019722 2 0.010
positive regulation of alcohol biosynthetic process GO:1902932 1 0.010

nsfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
brachydactyly DOID:0050581 0 0.015
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
dysostosis DOID:1934 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.010